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Mon May 1 15:08:57 2006

Papers by RJ Lefkowitz

Nodes: 972, Authors: 1059, Journals: 155, Outer References: 9343, Words: 1778
Yearly output  |  Document Type  |  Language  |  Institution  |  Institution with Subdivision  |  Country
Collection span: 1970 - 2006
View: Overview   Sorted by year, source, volume, issue, page.

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#LCRNCRNode / Date / Journal / AuthorLCSGCS
9011539901 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (8): 6258-6267
Tohgo A; Choy EW; Gesty-Palmer D; Pierce KL; Laporte S; et al.
The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation
1055
902926902 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (16): 14498-14506
Shenoy SK; Lefkowitz RJ
Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination
438
9031759903 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (24): 21663-21671
Miller WE; Houtz DA; Nelson CD; Kolattukudy PE; Lefkowitz RJ
G-protein-coupled receptor (GPCR) kinase phosphorylation and beta-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR
215
9041748904 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (28): 26295-26301
Hu LYA; Chen W; Martin NP; Whalen EJ; Premont RT; et al.
GIPC interacts with the beta(1)-adrenergic receptor and regulates beta(1)-adrenergic receptor-mediated ERK activation
217
9051550905 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (37): 35403-35411
Rapacciuolo A; Suvarna S; Barki-Harrington L; Luttrell LM; Cong M; et al.
Protein kinase A and G protein-coupled receptor kinase phosphorylation mediates beta-1 adrenergic receptor endocytosis through different pathways
125
9061033906 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (43): 41581-41584
Vines CM; Revankar CM; Maestas DC; LaRusch LL; Cimino DF; et al.
N-formyl peptide receptors internalize but do not recycle in the absence of arrestins
219
907423907 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (46): 45954-45959
Martin NP; Lefkowitz RJ; Shenoy SK
Regulation of V2 vasopressin receptor degradation by agonist-promoted ubiquitination
217
9081036908 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (51): 51334-51339
Povsic TJ; Kohout TA; Lefkowitz RJ
beta-arrestin1 mediates insulin-like growth factor 1 (IGF-1) activation of phosphatidylinositol 3-kinase (PI3K) and anti-apoptosis
612
909839909 2003 JOURNAL OF CLINICAL INVESTIGATION 112 (4): 566-574
Walker JKL; Fong AM; Lawson BL; Savov JD; Patel DD; et al.
beta-arrestin-2 regulates the development of allergic asthma
111
910532910 2003 JOURNAL OF IMMUNOLOGY 171 (11): 6128-6134
Kavelaars A; Vroon A; Raatgever RP; Fong AM; Premont RT; et al.
Increased acute inflammation, leukotriene B-4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6
19
#LCRNCRNode / Date / Journal / AuthorLCSGCS
911755911 2003 JOURNAL OF NEUROSCIENCE 23 (32): 10265-10273
Bohn LM; Gainetdinov RR; Sotnikova TD; Medvedev IO; Lefkowitz RJ; et al.
Enhanced rewarding properties of morphine, but not cocaine, in beta arrestin-2 knock-out mice
413
9124288912 2003 MOLECULAR PHARMACOLOGY 63 (1): 9-18
Kohout TA; Lefkowitz RJ
Regulation of g protein-coupled receptor kinases and arrestins during receptor desensitization
491
9131365913 2003 NEURON 38 (2): 291-303
Gainetdinov RR; Bohn LM; Sotnikova TD; Cyr M; Laakso A; et al.
Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice
735
914944914 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100 (3): 940-945
Baillie GS; Sood A; McPhee I; Gall I; Perry SJ; et al.
beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from G(s) to G(i)
149
9151428915 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100 (4): 1740-1744
Ahn S; Nelson CD; Garrison TR; Miller WE; Lefkowitz RJ
Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference
1644
9161330916 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100 (19): 10782-10787
Wei HJ; Ahn S; Shenoy SK; Karnik SS; Hunyady L; et al.
Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
1141
9171458917 2003 SCIENCE 300 (5623): 1256-1262
Lodowski DT; Pitcher JA; Capel WD; Lefkowitz RJ; Tesmer JJG
Keeping G proteins at bay: A complex between G protein-coupled receptor kinase 2 and G beta gamma
672
918922918 2003 SCIENCE 301 (5638): 1391-1394
Chen W; ten Berge D; Brown J; Ahn S; Hu LA; et al.
Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4
333
919425919 2003 SCIENCE 301 (5638): 1394-1397
Chen W; Kirkbride KC; How T; Nelson CD; Mo JY; et al.
beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling
143
920545920 2004 AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 286 (2): L312-L319
Walker JKL; Gainetdinov RR; Feldman DS; McFawn PK; Caron MG; et al.
G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation
17
#LCRNCRNode / Date / Journal / AuthorLCSGCS
92142164921 2004 ANNUAL REVIEW OF NEUROSCIENCE 27: 107-144
Gainetdinov RR; Premont RT; Bohn LM; Lefkowitz RJ; Caron MG
Desensitization of G protein-coupled receptors and neuronal functions
141
922650922 2004 BRITISH JOURNAL OF PHARMACOLOGY 141 (1): 55-64
Terman GW; Jin WZ; Cheong YP; Lowe J; Caron MG; et al.
G-protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal
18
9231135923 2004 CELLULAR SIGNALLING 16 (12): 1397-1403
Martin NP; Whalen EJ; Zamah MA; Pierce KL; Lefkowitz RJ
PKA-mediated phosphorylation of the beta(1)-adrenergic receptor promotes G(s)/G(i) switching
06
92400924 2004 CIRCULATION 110 (17): 92-92
Chakir K; Zhang SJ; Rhee MH; Blumer K; Lefkowitz RJ; et al.
Use-dependent beta 2-adrenergic receptor-GI coupling requires RGS and beta-ARK/PKA-mediated receptor phosphorylation
00
9251750925 2004 CURRENT OPINION IN CELL BIOLOGY 16 (2): 162-168
Lefkowitz RJ; Whalen EJ
beta-arrestins: traffic cops of cell signaling
241
92600926 2004 FASEB JOURNAL 18 (4): A463-A463
Walker JKL; Lawson BL; Schwartz DA; Lefkowitz RJ
beta-arrestin-2 regulation of lung eosinophilia in a mouse model of Th2-type airway inflammation
00
92700927 2004 FASEB JOURNAL 18 (8): C1-C1
Lefkowitz RJ
Seven-membrane spanning receptors
00
92800928 2004 FASEB JOURNAL 18 (8): C159-C159
Wang Q; Zhao JL; Brady A; Lefkowitz RJ; Greengard P; et al.
Spinophilin is a functional antagonist of arrestin in vitro and in vivo
00
929636929 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (3): 1810-1818
McLaughlin JP; Myers LC; Zarek PE; Caron MG; Lefkowitz RJ; et al.
Prolonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerance
112
9301430930 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (9): 7807-7811
Ahn S; Wei HJ; Garrison TR; Lefkowitz RJ
Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2
1020
#LCRNCRNode / Date / Journal / AuthorLCSGCS
931642931 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (24): 25590-25597
Galliera E; Jala VR; Trent JO; Bonecchi R; Signorelli P; et al.
beta-arrestin-dependent constitutive internalization of the human chemokine decoy receptor D6
011
9321440932 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (34): 35518-35525
Ahn SK; Shenoy SK; Wei HJ; Lefkowitz RJ
Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor
924
933929933 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (46): 48255-48261
Wei HJ; Ahn S; Barnes WG; Lefkowitz RJ
Stable interaction between beta-arrestin 2 and angiotensin type 1A receptor is required for beta-arrestin 2-mediated activation of extracellular signal-regulated kinases 1 and 2
06
934732934 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (53): 55419-55424
Ge L; Shenoy SK; Lefkowitz RJ; DeFea K
Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2
14
9351032935 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (53): 55744-55753
Xiao KH; Shenoy SK; Nobles K; Lefkowitz RJ
Activation-dependent conformational changes in beta-arrestin 2
16
936845936 2004 JOURNAL OF CLINICAL INVESTIGATION 113 (10): 1379-1382
Freedman NJ; Lefkowitz RJ
Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation
09
93700937 2004 JOURNAL OF CLINICAL ONCOLOGY 22 (14): 320S-320S
Shah MA; Kortmansky J; Gonen M; Tse A; Lefkowitz RJ; et al.
A phase I study of weekly irinotecan (CPT), cisplatin (CIS) and flavopiridol (F).
00
938248938 2004 JOURNAL OF NEUROSCIENCE 24 (19): 4576-4584
Xu M; Petraschka M; McLaughlin JP; Westenbroek RE; Caron MG; et al.
Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance
015
93900939 2004 JOURNAL OF PHARMACOLOGICAL SCIENCES 94: 2P-2P
Lefkowitz RJ
beta-arrestins: Master regulators of seven membrane spanning receptors
00
940533940 2004 MOLECULAR AND CELLULAR BIOLOGY 24 (20): 8929-8937
Usui I; Imamura T; Huang J; Satoh H; Shenoy SK; et al.
beta-arrestin-1 competitively inhibits insulin-induced ubiquitination and degradation of insulin receptor substrate 1
00
#LCRNCRNode / Date / Journal / AuthorLCSGCS
941637941 2004 MOLECULAR PHARMACOLOGY 66 (1): 106-112
Bohn LM; Dykstra LA; Lefkowitz RJ; Caron MG; Barak LS
Relative opioid efficacy is determined by the complements of the G protein-coupled receptor desensitization machinery
010
942215942 2004 NATURE METHODS 1 (3): 191-193
Shenoy SK; Lefkowitz RJ
Resonating to the music of ubiquitination
00
9431765943 2004 NEURON 42 (4): 581-593
Fukuto HS; Ferkey DM; Apicella AJ; Lans H; Sharmeen T; et al.
G protein-coupled receptor kinase function is essential for chemosensation in C-elegans
011
94402944 2004 NEW YORK TIMES BOOK REVIEW : 5-5
Lefkowitz RJ
The 'Secret Goldfish' (Derivation of the title)
00
9451240945 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (23): 8603-8607
Witherow DS; Garrison TR; Miller WE; Lefkowitz RJ
beta-Arrestin inhibits NF-kappa B activity by means of its interaction with the NF-kappa B inhibitor I kappa B alpha
17
946543946 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (32): 11886-11890
Dinudom A; Fotia AB; Lefkowitz RJ; Young JA; Kumar S; et al.
The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na+ channels
08
9471332947 2004 SCIENCE 304 (5679): 1940-1944
Wang Q; Zhao JL; Brady AE; Feng J; Allen PB; et al.
Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors
014
948328948 2004 SCIENCE 306 (5705): 2257-2260
Chen W; Ren XR; Nelson CD; Barak LS; Chen JK; et al.
Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2
023
94954104949 2004 TRENDS IN PHARMACOLOGICAL SCIENCES 25 (8): 413-422
Lefkowitz RJ
Historical review: A brief history and personal retrospective of seven-transmembrane receptors
031
950022950 2005 AMERICAN JOURNAL OF ROENTGENOLOGY 184 (2): 487-490
Gollub MJ; Lefkowitz RJ; Moskowitz CS; Ilson D; Kelsen D; et al.
Pelvic CT in patients with esophageal cancer
02
#LCRNCRNode / Date / Journal / AuthorLCSGCS
9511346951 2005 BIOCHEMICAL JOURNAL 387: 573-584
Milasta S; Evans NA; Ormiston L; Wilson S; Lefkowitz RJ; et al.
The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation
01
95200952 2005 BIOPHYSICAL JOURNAL 88 (1): 554A-554A
Xiao KH; Shenoy SK; Nobles K; Oas TG; Lefkowitz RJ
Activation dependent conformational changes in beta-arrestin 2
00
953951953 2005 CELL 122 (2): 261-273
Beaulieu JM; Sotnikova TD; Marion S; Lefkowitz RJ; Gainetdinov RR; et al.
An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
08
9541132954 2005 CIRCULATION 111 (5): 591-597
Tachibana H; Prasad SVN; Lefkowitz RJ; Koch WJ; Rockman HA
Level of beta-adrenergic receptor kinase 1 inhibition determines degree of cardiac dysfunction after chronic pressure overload-induced heart failure
02
95500955 2005 CIRCULATION 112 (17): U26-U26
Shenoy SK; Drake MT; Nelson CD; Houtz DA; Xiao KH; et al.
beta-arrestin-dependent, G-protein-independent ERK1/2 activation by the beta(2)-adrenergic receptor
00
95600956 2005 CIRCULATION 112 (17): U47-U47
Shenoy SK; Drake MT; Nelson CD; Houtz DA; Xiao KH; et al.
beta-arrestin dependent, G protein independent ERIK1/2 activation by the beta 2 adrenergic receptor
00
95700957 2005 CIRCULATION 112 (17): U237-U237
Rajagopal K; Whalen EJ; Violin JD; Rockman HA; Lefkowitz RJ
Beta-arrestin 2-dependent positive inotropic and lusitropic responses to angiotensin II receptor stimulation in cardiomyocytes
00
958046958 2005 CLINICAL CANCER RESEARCH 11 (10): 3836-3845
Shah MA; Kortmansky J; Motwani M; Drobnjak M; Gonen M; et al.
A phase I clinical trial of the sequential combination of irinotecan followed by flavopiridol
02
95900959 2005 FASEB JOURNAL 19 (5): A1099-A1099
Wang Q; Zhao JL; Lefkowitz RJ; Greengard P; Limbird L
Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors
00
960951960 2005 JOURNAL OF BIOLOGICAL CHEMISTRY 280 (9): 8041-8050
Barnes WG; Reiter E; Violin JD; Ren XR; Milligan G; et al.
beta-arrestin 1 and G(alpha q/11) coordinately activate RhoA and stress fiber formation following receptor stimulation
07
#LCRNCRNode / Date / Journal / AuthorLCSGCS
9611846961 2005 JOURNAL OF BIOLOGICAL CHEMISTRY 280 (15): 15315-15324
Shenoy SK; Lefkowitz RJ
Receptor-specific ubiquitination of beta-arrestin directs assembly and targeting of seven-transmembrane receptor signalosomes
18
9621339962 2005 JOURNAL OF BIOLOGICAL CHEMISTRY 280 (26): 24412-24419
Girnita L; Shenoy SK; Sehat B; Vasilcanu R; Girnita A; et al.
beta-arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase
24
96300963 2005 JOURNAL OF BONE AND MINERAL RESEARCH 20 (9): S182-S182
Gesty-Palmer D; Reiter E; Spurney RF; Luttrell LM; Lefkowitz RJ
Distinct conformations of the parathyroid hormone receptor mediate G protein and beta-arrestin dependent activation of ERK1/2.
00
964824964 2005 JOURNAL OF CLINICAL INVESTIGATION 115 (11): 2971-2974
Rajagopal K; Lefkowitz RJ; Rockman HA
When 7 transmembrane receptors are not G protein-coupled receptors
00
96500965 2005 JOURNAL OF MOLECULAR NEUROSCIENCE 26 (2-3): 293-294
Lefkowitz RJ
Summary of Wenner-Gren international symposium receptor-receptor interactions among heptaspanning membrane receptors: From structure to function
00
9661159966 2005 MOLECULAR PHARMACOLOGY 67 (4): 1229-1236
Hunton DL; Barnes WG; Kim J; Ren XR; Violin JD; et al.
beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis
14
967415967 2005 NATURE CELL BIOLOGY 7 (12): 1059-1061
Shenoy SK; Lefkowitz RJ
Receptor regulation: beta-arrestin moves up a notch
00
9682137968 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (5): 1442-1447
Kim J; Ahn S; Ren XR; Whalen EJ; Reiter E; et al.
Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling
310
9692637969 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (5): 1448-1453
Ren XR; Reiter E; Ahn S; Kim J; Chen W; et al.
Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor
28
970020970 2006 AMERICAN JOURNAL OF SURGERY 191 (1): 134-138
Sarela AI; Lefkowitz RJ; Brennan MF; Karpeh MS
Selection of patients with gastric adenocarcinoma for laparoscopic staging
00
#LCRNCRNode / Date / Journal / AuthorLCSGCS
9712253971 2006 JOURNAL OF BIOLOGICAL CHEMISTRY 281 (2): 1261-1273
Shenoy SK; Drake MT; Nelson CD; Houtz DA; Xiao KH; et al.
beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta 2 adrenergic receptor
01
9721247972 2006 JOURNAL OF BIOLOGICAL CHEMISTRY 281 (16): 10856-10864
Gesty-Palmer D; Chen MY; Reiter E; Ahn S; Nelson CD; et al.
Distinct beta-arrestin-and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation
00

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