GCS >= 120
Nodes: 55, Links: 94
GCS >= 120; Min: 120, Max: 1680 (GCS scaled)
1. 6 1952 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 74 (9): 2286-2292
KOSHLAND DE
EFFECT OF CATALYSTS ON THE HYDROLYSIS OF ACETYL PHOSPHATE - NUCLEOPHILIC DISPLACEMENT MECHANISMS IN ENZYMATIC REACTIONS
LCR: 1 NCR: 34 LCS: 5 GCS: 170
2. 8 1953 BIOLOGICAL REVIEWS OF THE CAMBRIDGE PHILOSOPHICAL SOCIETY 28 (4): 416-436
KOSHLAND DE
STEREOCHEMISTRY AND THE MECHANISM OF ENZYMATIC REACTIONS
LCR: 3 NCR: 90 LCS: 10 GCS: 380
3. 30 1958 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 44 (2): 98-104
KOSHLAND DE
APPLICATION OF A THEORY OF ENZYME SPECIFICITY TO PROTEIN SYNTHESIS
LCR: 3 NCR: 27 LCS: 16 GCS: 629
4. 37 1960 ADVANCES IN ENZYMOLOGY AND RELATED SUBJECTS OF BIOCHEMISTRY 22: 45-97
KOSHLAND DE
THE ACTIVE SITE AND ENZYME ACTION
LCR: 8 NCR: 219 LCS: 7 GCS: 229
5. 42 1960 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 82 (13): 3329-3333
THOMA JA; KOSHLAND DE
COMPETITIVE INHIBITION BY SUBSTRATE DURING ENZYME ACTION - EVIDENCE FOR THE INDUCEDFIT THEORY
LCR: 2 NCR: 16 LCS: 13 GCS: 132
6. 49 1962 JOURNAL OF BIOLOGICAL CHEMISTRY 237 (8): 2493-&
RAY WJ; KOSHLAND DE
IDENTIFICATION OF AMINO ACIDS INVOLVED IN PHOSPHOGLUCOMUTASE ACTION
LCR: 2 NCR: 35 LCS: 9 GCS: 241
7. 54 1963 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 28: 473-&
KOSHLAND DE
ROLE OF FLEXIBILITY IN ENZYME ACTION
LCR: 4 NCR: 20 LCS: 5 GCS: 141
8. 67 1964 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 86 (7): 1448-&
KOSHLAND DE; KARKHANIS YD; LATHAM HG
ENVIRONMENTALLY-SENSITIVE REAGENT WITH SELECTIVITY FOR TRYPTOPHAN RESIDUE IN PROTEINS
LCR: 1 NCR: 7 LCS: 5 GCS: 180
9. 76 1965 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 87 (5): 1126-&
HORTON HR; KOSHLAND DE
A HIGHLY REACTIVE COLORED REAGENT WITH SELECTIVITY FOR TRYPTOPHAN RESIDUE IN PROTEINS - 2-HYDROXY-5-NITROBENZYL BROMIDE
LCR: 2 NCR: 18 LCS: 4 GCS: 211
10. 78 1966 BIOCHEMISTRY 5 (1): 365-&
KOSHLAND DE; NEMETHY G; FILMER D
COMPARISON OF EXPERIMENTAL BINDING DATA AND THEORETICAL MODELS IN PROTEINS CONTAINING SUBUNITS
LCR: 2 NCR: 24 LCS: 38 GCS: 1680
11. 81 1966 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 88 (9): 2057-&
HOARE DG; KOSHLAND DE
A PROCEDURE FOR SELECTIVE MODIFICATION OF CARBOXYL GROUPS IN PROTEINS
LCR: 1 NCR: 22 LCS: 3 GCS: 131
12. 83 1966 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 56 (5): 1606-&
NEET KE; KOSHLAND DE
CONVERSION OF SERINE AT ACTIVE SITE OF SUBTILISIN TO CYSTEINE - A CHEMICAL MUTATION
LCR: 3 NCR: 31 LCS: 2 GCS: 147
13. 87 1967 JOURNAL OF BIOLOGICAL CHEMISTRY 242 (10): 2447-&
HOARE DG; KOSHLAND DE
A METHOD FOR QUANTITATIVE MODIFICATION AND ESTIMATION OF CARBOXYLIC ACID GROUPS IN PROTEINS
LCR: 1 NCR: 21 LCS: 4 GCS: 849
14. 89 1967 JOURNAL OF BIOLOGICAL CHEMISTRY 242 (24): 5771-&
BARMAN TE; KOSHLAND DE
A COLORIMETRIC PROCEDURE FOR QUANTITATIVE DETERMINATION OF TRYPTOPHAN RESIDUES IN PROTEINS
LCR: 2 NCR: 20 LCS: 2 GCS: 294
15. 94 1968 ANNUAL REVIEW OF BIOCHEMISTRY 37: 359-&
KOSHLAND DE; NEET KE
CATALYTIC AND REGULATORY PROPERTIES OF ENZYMES
LCR: 13 NCR: 250 LCS: 12 GCS: 486
16. 95 1968 BIOCHEMISTRY 7 (11): 4011-&
CONWAY A; KOSHLAND DE
NEGATIVE COOPERATIVITY IN ENZYME ACTION . BINDING OF DIPHOSPHOPYRIDINE NUCLEOTIDE TO GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE
LCR: 6 NCR: 44 LCS: 12 GCS: 435
17. 96 1968 BIOCHIMICA ET BIOPHYSICA ACTA 160 (2): 272-&
CARRAWAY KL; KOSHLAND DE
REACTION OF TYROSINE RESIDUES IN PROTEINS WITH CARBODIIMIDE REAGENTS
LCR: 1 NCR: 6 LCS: 2 GCS: 175
18. 102 1969 BIOCHEMISTRY 8 (11): 4656-&
TEIPEL J; KOSHLAND DE
SIGNIFICANCE OF INTERMEDIARY PLATEAU REGIONS IN ENZYME SATURATION CURVES
LCR: 3 NCR: 16 LCS: 2 GCS: 173
19. 108 1969 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 62 (4): 1121-&
LEVITZKI A; KOSHLAND DE
NEGATIVE COOPERATIVITY IN REGULATORY ENZYMES
LCR: 5 NCR: 26 LCS: 8 GCS: 414
20. 113 1970 BIOCHEMISTRY 9 (17): 3337-&
COOK RA; KOSHLAND DE
POSITIVE AND NEGATIVE COOPERATIVITY IN YEAST GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE
LCR: 3 NCR: 21 LCS: 6 GCS: 132
21. 122 1970 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 66 (2): 445-&
STORM DR; KOSHLAND DE
A SOURCE FOR SPECIAL CATALYTIC POWER OF ENZYMES - ORBITAL STEERIN
LCR: 2 NCR: 33 LCS: 8 GCS: 163
22. 125 1971 BIOCHEMISTRY 10 (5): 792-&
TEIPEL JW; KOSHLAND DE
KINETIC ASPECTS OF CONFORMATIONAL CHANGES IN PROTEINS .1. RATE OF REGAIN OF ENZYME ACTIVITY FROM DENATURED PROTEINS
LCR: 2 NCR: 25 LCS: 2 GCS: 173
23. 128 1971 BIOCHEMISTRY 10 (18): 3371-&
LEVITZKI A; STALLCUP WB; KOSHLAND DE
HALF-OF-SITES REACTIVITY AND CONFORMATIONAL STATES OF CYTIDINE TRIPHOSPHATE SYNTHETASE
LCR: 4 NCR: 32 LCS: 12 GCS: 205
24. 146 1972 NATURE-NEW BIOLOGY 236 (65): 120-&
DAHLQUIS.FW; LOVELY P; KOSHLAND DE
QUANTITATIVE ANALYSIS OF BACTERIAL MIGRATION IN CHEMOTAXIS
LCR: 0 NCR: 15 LCS: 0 GCS: 121
25. 147 1972 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 69 (9): 2509-&
MACNAB RM; KOSHLAND DE
GRADIENT-SENSING MECHANISM IN BACTERIAL CHEMOTAXIS
LCR: 0 NCR: 14 LCS: 61 GCS: 475
26. 154 1973 SCIENCE 181 (4094): 60-63
TSANG N; MACNAB R; KOSHLAND DE
COMMON MECHANISM FOR REPELLENTS AND ATTRACTANTS IN BACTERIAL CHEMOTAXIS
LCR: 2 NCR: 17 LCS: 28 GCS: 149
27. 178 1975 JOURNAL OF MOLECULAR BIOLOGY 95 (2): 201-212
CORNISHBOWDEN A; KOSHLAND DE
DIAGNOSTIC USES OF HILL (LOGIT AND NERNST) PLOTS
LCR: 4 NCR: 21 LCS: 1 GCS: 182
28. 181 1975 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 72 (2): 710-713
SPUDICH JL; KOSHLAND DE
QUANTITATION OF SENSORY RESPONSE IN BACTERIAL CHEMOTAXIS
LCR: 3 NCR: 22 LCS: 31 GCS: 158
29. 201 1977 JOURNAL OF BIOLOGICAL CHEMISTRY 252 (8): 2793-2795
VANDERWERF P; KOSHLAND DE
IDENTIFICATION OF A GAMMA-GLUTAMYL METHYL-ESTER IN BACTERIAL-MEMBRANE PROTEIN INVOLVED IN CHEMOTAXIS
LCR: 1 NCR: 22 LCS: 20 GCS: 132
30. 204 1977 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 74 (2): 533-537
SPRINGER WR; KOSHLAND DE
IDENTIFICATION OF A PROTEIN METHYLTRANSFERASE AS CHER GENE PRODUCT IN BACTERIAL SENSING SYSTEM
LCR: 2 NCR: 25 LCS: 46 GCS: 267
31. 217 1978 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 75 (8): 3659-3663
STOCK JB; KOSHLAND DE
PROTEIN METHYLESTERASE INVOLVED IN BACTERIAL SENSING
LCR: 5 NCR: 36 LCS: 40 GCS: 230
32. 228 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254 (19): 9695-9702
CLARKE S; KOSHLAND DE
MEMBRANE-RECEPTORS FOR ASPARTATE AND SERINE IN BACTERIAL CHEMOTAXIS
LCR: 5 NCR: 26 LCS: 38 GCS: 156
33. 242 1980 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 77 (12): 7157-7161
WANG EA; KOSHLAND DE
RECEPTOR STRUCTURE IN THE BACTERIAL SENSING SYSTEM
LCR: 8 NCR: 36 LCS: 33 GCS: 124
34. 244 1981 ANNUAL REVIEW OF BIOCHEMISTRY 50: 765-782
KOSHLAND DE
BIOCHEMISTRY OF SENSING AND ADAPTATION IN A SIMPLE BACTERIAL SYSTEM
LCR: 21 NCR: 90 LCS: 27 GCS: 194
35. 252 1981 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 78 (11): 6840-6844
GOLDBETER A; KOSHLAND DE
AN AMPLIFIED SENSITIVITY ARISING FROM COVALENT MODIFICATION IN BIOLOGICAL-SYSTEMS
LCR: 2 NCR: 26 LCS: 14 GCS: 216
36. 258 1982 NATURE 300 (5891): 458-460
LAPORTE DC; KOSHLAND DE
A PROTEIN WITH KINASE AND PHOSPHATASE-ACTIVITIES INVOLVED IN REGULATION OF TRICARBOXYLIC-ACID CYCLE
LCR: 1 NCR: 11 LCS: 15 GCS: 153
37. 260 1982 SCIENCE 217 (4556): 220-225
KOSHLAND DE; GOLDBETER A; STOCK JB
AMPLIFICATION AND ADAPTATION IN REGULATORY AND SENSORY SYSTEMS
LCR: 7 NCR: 51 LCS: 21 GCS: 193
38. 270 1983 NATURE 305 (5932): 286-290
LAPORTE DC; KOSHLAND DE
PHOSPHORYLATION OF ISOCITRATE DEHYDROGENASE AS A DEMONSTRATION OF ENHANCED SENSITIVITY IN COVALENT REGULATION
LCR: 4 NCR: 22 LCS: 20 GCS: 123
39. 271 1983 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 80 (16): 4894-4898
GUTTERSON NI; KOSHLAND DE
REPLACEMENT AND AMPLIFICATION OF BACTERIAL GENES WITH SEQUENCES ALTERED INVITRO
LCR: 6 NCR: 37 LCS: 2 GCS: 179
40. 272 1983 SCIENCE 220 (4601): 1016-1020
RUSSO AF; KOSHLAND DE
SEPARATION OF SIGNAL TRANSDUCTION AND ADAPTATION FUNCTIONS OF THE ASPARTATE RECEPTOR IN BACTERIAL SENSING
LCR: 11 NCR: 47 LCS: 50 GCS: 193
41. 296 1985 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 82 (23): 7989-7993
STOCK A; KOSHLAND DE; STOCK J
HOMOLOGIES BETWEEN THE SALMONELLA-TYPHIMURIUM CHEY PROTEIN AND PROTEINS INVOLVED IN THE REGULATION OF CHEMOTAXIS, MEMBRANE-PROTEIN SYNTHESIS, AND SPORULATION
LCR: 10 NCR: 43 LCS: 8 GCS: 141
42. 326 1986 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83 (16): 5822-5824
BOLLAG GE; ROTH RA; BEAUDOIN J; MOCHLYROSEN D; KOSHLAND DE
PROTEIN-KINASE-C DIRECTLY PHOSPHORYLATES THE INSULIN-RECEPTOR INVITRO AND REDUCES ITS PROTEIN-TYROSINE KINASE-ACTIVITY
LCR: 0 NCR: 24 LCS: 3 GCS: 243
43. 356 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262 (5): 2291-2297
MOCHLYROSEN D; KOSHLAND DE
DOMAIN-STRUCTURE AND PHOSPHORYLATION OF PROTEIN-KINASE-C
LCR: 0 NCR: 30 LCS: 10 GCS: 161
44. 362 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262 (22): 10422-10425
THORSNESS PE; KOSHLAND DE
INACTIVATION OF ISOCITRATE DEHYDROGENASE BY PHOSPHORYLATION IS MEDIATED BY THE NEGATIVE CHARGE OF THE PHOSPHATE
LCR: 2 NCR: 26 LCS: 13 GCS: 184
45. 382 1987 SCIENCE 237 (4822): 1596-1600
FALKE JJ; KOSHLAND DE
GLOBAL FLEXIBILITY IN A SENSORY RECEPTOR - A SITE-DIRECTED CROSS-LINKING APPROACH
LCR: 6 NCR: 41 LCS: 31 GCS: 209
46. 395 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263 (13): 6268-6275
MILLIGAN DL; KOSHLAND DE
SITE-DIRECTED CROSS-LINKING - ESTABLISHING THE DIMERIC STRUCTURE OF THE ASPARTATE RECEPTOR OF BACTERIAL CHEMOTAXIS
LCR: 7 NCR: 43 LCS: 28 GCS: 185
47. 397 1988 NATURE 331 (6156): 499-504
KOSHLAND DE; MITCHISON TJ; KIRSCHNER MW
POLEWARDS CHROMOSOME MOVEMENT DRIVEN BY MICROTUBULE DEPOLYMERIZATION INVITRO
LCR: 0 NCR: 35 LCS: 0 GCS: 225
48. 431 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264 (36): 21770-21778
SANDERS DA; GILLECECASTRO BL; STOCK AM; BURLINGAME AL; KOSHLAND DE
IDENTIFICATION OF THE SITE OF PHOSPHORYLATION OF THE CHEMOTAXIS RESPONSE REGULATOR PROTEIN, CHEY
LCR: 2 NCR: 62 LCS: 2 GCS: 224
49. 433 1989 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 86 (22): 8635-8639
HURLEY JH; THORSNESS PE; RAMALINGAM V; HELMERS NH; KOSHLAND DE; et al.
STRUCTURE OF A BACTERIAL ENZYME REGULATED BY PHOSPHORYLATION, ISOCITRATE DEHYDROGENASE
LCR: 3 NCR: 39 LCS: 15 GCS: 158
50. 487 1990 SCIENCE 249 (4967): 408-411
FLINT AJ; PALADINI RD; KOSHLAND DE
AUTOPHOSPHORYLATION OF PROTEIN KINASE-C AT 3-SEPARATED REGIONS OF ITS PRIMARY SEQUENCE
LCR: 2 NCR: 33 LCS: 1 GCS: 120
51. 489 1990 SCIENCE 249 (4972): 1012-1016
HURLEY JH; DEAN AM; SOHL JL; KOSHLAND DE; STROUD RM
REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE-SITE
LCR: 6 NCR: 24 LCS: 18 GCS: 188
52. 500 1991 BIOCHEMISTRY 30 (35): 8671-8678
HURLEY JH; DEAN AM; KOSHLAND DE; STROUD RM
CATALYTIC MECHANISM OF NADP+-DEPENDENT ISOCITRATE DEHYDROGENASE - IMPLICATIONS FROM THE STRUCTURES OF MAGNESIUM ISOCITRATE AND NADP+ COMPLEXES
LCR: 5 NCR: 41 LCS: 19 GCS: 184
53. 532 1991 SCIENCE 254 (5036): 1342-1347
MILBURN MV; PRIVE GG; MILLIGAN DL; SCOTT WG; YEH J; et al.
3-DIMENSIONAL STRUCTURES OF THE LIGAND-BINDING DOMAIN OF THE BACTERIAL ASPARTATE RECEPTOR WITH AND WITHOUT A LIGAND
LCR: 8 NCR: 47 LCS: 26 GCS: 264
54. 573 1992 SCIENCE 258 (5090): 1861-1861
KOSHLAND DE
THE MOLECULE OF THE YEAR
LCR: 0 NCR: 0 LCS: 0 GCS: 151
55. 574 1992 SCIENCE 258 (5090): 1862-1865
CULOTTA E; KOSHLAND DE
NO NEWS IS GOOD-NEWS
LCR: 0 NCR: 1 LCS: 0 GCS: 266