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Tue Aug 31 16:33:13 2004
Naturally secreted oligomers of amyloid beta protein potently
inhibit hippocampal long-term potentiation in vivo

Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R,
Wolfe MS, Rowan MJ, Selkoe DJ
NATURE 416 (6880): 535-539 APR 4 2002
and the citing papers

Nodes: 246
Authors: 958, Journals: 112, Outer References: 9412
Collection span: 2002 - 2004
View: Overview. Sorted by year, source, volume, issue, page.
Page 1:  1 (1)  2 (101)  3 (201)
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
11491 2002 AMERICAN JOURNAL OF PATHOLOGY 161(5):1935-1948
Sousa MM; Fernandes R; Palha JA; Taboada A; Vieira P; Saraiva MJ
Evidence for early cytotoxic aggregates in transgenic mice for human transthyretin Leu55Pro
27
211002 2002 ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 37 37:31-40
Morgan TE; Krafft GA
Emerging themes in Alzheimer's disease research: Paradigm shift in drug discovery
00
311553 2002 ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS 3:67-99
Selkoe DJ; Podlisny MB
Deciphering the genetic basis of Alzheimer's disease
222
41344 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 296(5):1317-1321
Rovira C; Arbez N; Mariani J
A beta(25-35) and A beta(1-40) act on different calcium channels in CA1 hippocampal neurons
04
52535 2002 BIOCHEMICAL SOCIETY TRANSACTIONS 30:574-578
Wisniewski T; Brown DR; Sigurdsson EM
Therapeutics in Alzheimer's and prion diseases
01
61456 2002 EMBO JOURNAL 21(22):6005-6014
Sandilands A; Hutcheson AM; Long HA; Prescott AR; Vrensen G; Loster J; Klopp N; Lutz RB; Graw J; Masaki S; Dobson CM; MacPhee CE; Quinlan RA
Altered aggregation properties of mutant gamma-crystallins cause inherited cataract
313
71447 2002 FASEB JOURNAL 16(13)
Kim HJ; Chae SC; Lee DK; Chromy B; Lee SC; Park YC; Klein WL; Krafft GA; Hong ST
Selective neuronal degeneration induced by soluble oligomeric amyloid beta-protein
00
81578 2002 FREE RADICAL BIOLOGY AND MEDICINE 33(9):1194-1199
Smith MA; Casadesus G; Joseph JA; Perry G
Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain
09
91649 2002 FREE RADICAL RESEARCH 36(12):1307-1313
Butterfield DA
Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: Implications for neurodegeneration in Alzheimer's disease brain. A review
232
1026810 2002 HUMAN MOLECULAR GENETICS 11(23):2895-2904
Chan HYE; Warrick JM; Andriola I; Merry D; Bonini NM
Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila
319
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
1112611 2002 HUMAN MOLECULAR GENETICS 11(25):3209-3219
Deery EC; Vithana EN; Newbold RJ; Gallon VA; Bhattacharya SS; Warren MJ; Hunt DM; Wilkie SE
Disease mechanism for retinitis pigmentosa (RP11) caused by mutations in the splicing factor gene PRPF31
06
1213512 2002 INTERNATIONAL IMMUNOPHARMACOLOGY 2(13-14):1833-1840
Jong YJI; Dalemar LR; Seehra K; Baenziger NL
Bradykinin receptor modulation in cellular models of aging and Alzheimer's disease
01
1316913 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(35):32046-32053
Dahlgren KN; Manelli AM; Stine WB; Baker LK; Krafft GA; LaDu MJ
Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability
2437
1415514 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(36):33012-33017
Mohajeri MH; Saini K; Schultz JG; Wollmer MA; Hock C; Nitsch RM
Passive immunization against beta-amyloid peptide protects central nervous system (CNS) neurons from increased vulnerability associated with an Alzheimer's disease-causing mutation
18
1514815 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(43):40173-40176
Hou LM; Kang I; Marchant RE; Zagorski MG
Methionine 35 oxidation reduces fibril assembly of the amyloid A beta-(1-42) peptide of Alzheimer's disease
712
1613516 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(43):41032-41037
Poirier MA; Li HL; Macosko J; Cai SW; Amzel M; Ross CA
Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization
827
1716517 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(45):42881-42890
Lashuel HA; Hartley DM; Balakhaneh D; Aggarwal A; Teichberg S; Callaway DJE
New class of inhibitors of amyloid-beta fibril formation - Implications for the mechanism of pathogenesis in Alzheimer's disease
16
1821518 2002 JOURNAL OF CLINICAL INVESTIGATION 110(9):1219-1220
Perlmutter DH
The cellular response to aggregated proteins associated with human disease
02
1918019 2002 JOURNAL OF CLINICAL INVESTIGATION 110(9):1221-1232
Horwich A
Protein aggregation in disease: a role for folding intermediates forming specific multimeric interactions
319
2016520 2002 JOURNAL OF CLINICAL INVESTIGATION 110(10):1375-1381
Selkoe DJ
Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease
222
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
2114921 2002 JOURNAL OF MOLECULAR BIOLOGY 319(5):1279-1290
Wurth C; Guimard NK; Hecht MH
Mutations that reduce aggregation of the Alzheimer's A beta 42 peptide: an unbiased search for the sequence determinants of A beta amyloidogenesis
212
2218322 2002 JOURNAL OF NEUROCHEMISTRY 83(3):481-489
Bahr BA; Bendiske J
The neuropathogenic contributions of lysosomal dysfunction
120
23115423 2002 JOURNAL OF NEUROSCIENCE RESEARCH 69(5):567-577
Kirkitadze MD; Bitan G; Teplow DB
Paradigm shifts in Alzheimer's disease and other neuro degenerative disorders: The emerging role of oligomeric assemblies
1029
2417224 2002 JOURNAL OF NEUROSCIENCE RESEARCH 70(3):298-308
Watson JB; Khorasani H; Persson A; Huang KP; Huang FL; O'Dell TJ
Age-related deficits in long-term potentiation are insensitive to hydrogen peroxide: Coincidence with enhanced autophosphorylation of Ca2+/calmodulin-dependent protein kinase II
01
25169825 2002 JOURNAL OF NEUROSCIENCE RESEARCH 70(3):402-437
Teter B; Ashford JW
Neuroplasticity in Alzheimer's disease
03
2613126 2002 JOURNAL OF PEPTIDE SCIENCE 8(10):578-588
Rabanal F; Tusell JM; Sastre L; Quintero MR; Cruz M; Grillo D; Pons M; Albericio F; Serratosa J; Giralt E
Structural, kinetic and cytotoxicity aspects of 12-28 beta-amyloid protein fragment: A reappraisal
11
271227 2002 LANCET 359(9313):1214-1214
Frankish H
Researchers uncover a shared mechanism for protein aggregation disorders
00
2812728 2002 MOLECULAR BRAIN RESEARCH 106(1-2):94-100
Kubo T; Nishimura S; Oda T
Amyloid beta-peptide alters the distribution of early endosomes and inhibits phosphorylation of Akt in the presence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)
00
29118829 2002 MOLECULAR NEUROBIOLOGY 26(2-3):299-316
Echeverria V; Cuello AC
Intracellular A-beta amyloid, a sign for worse things to come?
06
3023230 2002 MOLECULAR VISION 8(39):372-388
Chen T; Li XL; Yang Y; Church RL
Localization of lens intrinsic membrane protein MP19 and mutant protein MP19(To3) using fluorescent expression vectors
02
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
3111031 2002 NATURE 416(6880):483-484
Ellis RJ; Pinheiro TJT
Danger - misfolding proteins
927
3203032 2002 NATURE 416(6880):535-539
Walsh DM; Klyubin I; Fadeeva JV; Cullen WK; Anwyl R; Wolfe MS; Rowan MJ; Selkoe DJ
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
245255
3311333 2002 NATURE 418(6895):291-291
Lashuel HA; Hartley D; Petre BM; Walz T; Lansbury PT
Neurodegenerative disease - Amyloid pores from pathogenic mutations
2093
3431534 2002 NATURE MEDICINE 8(11):1195-1196
Haass C
New hope for Alzheimer disease vaccine
17
3513635 2002 NATURE MEDICINE 8(11):1263-1269
McLaurin J; Cecal R; Kierstead ME; Tian X; Phinney AL; Manea M; French JE; Lambermon MHL; Darabie AA; Brown ME; Janus C; Chishti MA; Horne P; Westaway D; Fraser PE; Mount HTJ; Przybylski M; St George-Hyslop P
Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis
540
3613036 2002 NATURE MEDICINE 8(11):1270-1275
Hock C; Konietzko U; Papassotiropoulos A; Wollmer A; Streffer J; von Rotz RC; Davey G; Moritz E; Nitsch RM
Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease
537
371237 2002 NATURE REVIEWS DRUG DISCOVERY 1(5):329-329
Smith A
The early results of misfolding
00
3839638 2002 NATURE REVIEWS DRUG DISCOVERY 1(11):859-866
Wolfe MS
Therapeutic strategies for Alzheimer's disease
126
391239 2002 NATURE REVIEWS MOLECULAR CELL BIOLOGY 3(5):314-314
Smith A
Neurodegenerative disease - The early results of misfolding
00
401240 2002 NATURE REVIEWS NEUROSCIENCE 3(5):335-335
Smith A
Neurodegenerative disorders - The early results of misfolding
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
4115341 2002 NATURE STRUCTURAL BIOLOGY 9(5):323-325
Kelly JW
Towards an understanding of amyloidogenesis
210
4214142 2002 NEUROBIOLOGY OF DISEASE 11(2):330-340
Kumar-Singh S; Julliams A; Nuydens R; Ceuterick C; Labeur C; Serneels S; Vennekens K; Van Osta P; Geerts H; De Strooper B; Van Broeckhoven C
In vitro studies of Flemish, Dutch, and wild-type beta-amyloid provide evidence for two-staged neurotoxicity
02
43124143 2002 NEUROMOLECULAR MEDICINE 2(2):167-196
Chan SL; Furukawa K; Mattson MP
Presenilins and APP in neuritic and synaptic plasticity - Implications for the pathogenesis of Alzheimer's disease
08
4413944 2002 NEURON 34(6):905-919
Watase K; Weeber EJ; Xu BS; Antalffy B; Yuva-Paylor L; Hashimoto K; Kano M; Atkinson R; Sun YL; Armstrong DL; Sweatt JD; Orr HT; Paylor R; Zoghbi HY
A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration
539
4512345 2002 NEURON 35(1):9-12
Muchowskil PJ
Protein misfolding, amyloid formation, and neurodegeneration: A critical role for molecular chaperones?
432
4623446 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99:16407-16411
Bonini NM
Chaperoning brain degeneration
426
4728347 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99:16412-16418
Sakahira H; Breuer P; Hayer-Hartl MK; Hartl FU
Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity
420
4817948 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99:16419-16426
Chiti F; Calamai M; Taddei N; Stefani M; Ramponi G; Dobson CM
Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases
423
4914949 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(13):8666-8671
Edbauer D; Winkler E; Haass C; Steiner H
Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation
369
5012850 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(20):13217-13221
Vitolo OV; Sant'Angelo A; Costanzo V; Battaglia F; Arancio O; Shelanski M
Amyloid beta-peptide inhibition of the PKA/CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signaling
920
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
51150651 2002 PROGRESS IN NEUROBIOLOGY 68(3):209-245
Auld DS; Kornecook TJ; Bastianetto S; Quirion R
Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies
119
5217452 2002 SCIENCE 296(5575):1991-1995
Taylor JP; Hardy J; Fischbeck KH
Biomedicine - Toxic proteins in neurodegenerative disease
9105
5319153 2002 SCIENCE 297(5580):353-356
Hardy J; Selkoe DJ
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
41281
5413454 2002 SCIENCE 298(5594):789-791
Selkoe DJ
Alzheimer's disease is a synaptic failure
2198
5511855 2002 SCIENCE 298(5595):963-964
Selkoe DJ; Hardy J
The search for an amyloid solution - Response
11
5612056 2002 STRUCTURE 10(8):1031-1036
Wetzel R
Ideas of order for amyloid fibril structure
222
5724957 2003 AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS 10(2):80-85
Robakis NK
An Alzheimer's disease hypothesis based on transcriptional dysregulation
01
5823558 2003 ANNALS OF NEUROLOGY 54(6):781-789
Lu DC; Shaked GM; Masliah E; Bredesen DE; Koo EH
Amyloid beta protein toxicity mediated by the formation of amyloid-beta protein precursor complexes
11
59619959 2003 ANNUAL REVIEW OF NEUROSCIENCE 26:267-298
Caughey B; Lansbury PT
Protofibrils, pores, fibrils, and neurodegeneration: Separating the responsible protein aggregates from the innocent bystanders
731
60717860 2003 ANNUAL REVIEW OF NEUROSCIENCE 26:627-656
Bonini NM; Fortini ME
Human neurodegenerative disease modeling using Drosophila
03
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
61115061 2003 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 43:545-584
Selkoe DJ; Schenk D
Alzheimer's disease: Molecular understanding predicts amyloid-based therapeutics
729
6214762 2003 BEHAVIOURAL BRAIN RESEARCH 147(1-2):73-82
Romano A; Serafino A; Krasnowska E; Ciotti MT; Calissano P; Ruberti F; Galli C
Neuronal fibrillogenesis: amyloid fibrils from primary neuronal cultures impair long-term memory in the crab Chasmagnathus
00
63518263 2003 BEHAVIOURAL PHARMACOLOGY 14(5-6):419-438
Higgins GA; Jacobsen H
Transgenic mouse models of Alzheimer's disease: phenotype and application
02
6412064 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 301(3):699-703
Takata K; Kitamura Y; Kakimura J; Shibagaki K; Tsuchiya D; Taniguchi T; Smith MA; Perry G; Shimohama S
Role of high mobility group protein-1 (HMG1) in amyloid-beta homeostasis
02
6523765 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 303(2):496-503
Tobisawa S; Hozumi Y; Arawaka S; Koyama S; Wada M; Nagai M; Aoki M; Itoyama Y; Goto K; Kato T
Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice
02
6625866 2003 BIOCHEMISTRY 42(15):4492-4498
Kumita JR; Weston CJ; Choo-Smith LP; Woolley GA; Smart OS
Prevention of peptide fibril formation in an aqueous environment by mutation of a single residue to Aib
01
6714867 2003 BIOCHEMISTRY 42(31):9507-9514
Wang SSS; Tobler SA; Good TA; Fernandez EJ
Hydrogen exchange-mass spectrometry analysis of beta-Amyloid peptide structure
12
6837968 2003 BIOCHEMISTRY 42(36):10863-10873
Cottingham MG; Voskuil JLA; Vaux DJT
The intact human acetylcholinesterase C-terminal oligomerization domain is alpha-helical in situ and in isolation, but a shorter fragment forms beta-sheet-rich amyloid fibrils and protofibrillar oligomers
04
6934469 2003 BIOCHEMISTRY 42(40):11682-11692
Miller DL; Currie JR; Mehta PD; Potempska A; Hwang YW; Wegiel J
Humoral immune response to fibrillar beta-amyloid peptide
01
7097670 2003 BIOCHEMISTRY 42(44):12749-12760
Chromy BA; Nowak RJ; Lambert MP; Viola KL; Chang L; Velasco PT; Jones BW; Fernandez SJ; Lacor PN; Horowitz P; Finch CE; Krafft GA; Klein WL
Self-assembly of A beta(1-42) into globular neurotoxins
14
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
7142771 2003 BIOCHEMISTRY 42(48):14092-14098
Kheterpal I; Lashuel HA; Hartley DM; Wlaz T; Lansbury PT; Wetzel R
A beta protofibrils possess a stable core structure resistant to hydrogen exchange
13
7226072 2003 BIOESSAYS 25(3):283-288
Robinson SR; Bishop GM; Munch G
Alzheimer vaccine: amyloid-beta on trial
25
7331273 2003 BIOESSAYS 25(10):1024-1024
Koudinova NV
Alzheimer's amyloid beta oligomers and lipoprotein apoA beta: mistaken identity is possible
11
7413774 2003 BRAIN RESEARCH 968(2):263-272
Raymond CR; Ireland DR; Abraham WC
NMDA receptor regulation by amyloid-beta does not account for its inhibition of LTP in rat hippocampus
44
7512175 2003 BRAIN RESEARCH 990(1-2):141-147
Tohda C; Tamura T; Komatsu K
Repair of amyloid beta(25-35)-induced memory impairment and synaptic loss by a Kampo formula, Zokumei-to
11
7616676 2003 CHEMISTRY & BIOLOGY 10(2):149-159
Kapurniotu A; Buck A; Weber M; Schmauder A; Hirsch T; Bernhagen J; Tatarek-Nossol M
Conformational restriction via cyclization in beta-amyloid peptide A beta(1-28) leads to an inhibitor of A beta(1-28) amyloidogenesis and cytotoxicity
00
77513777 2003 CNS DRUGS 17(9):641-652
Butterfield DA; Pocernich CB
The glutamatergic system and Alzheimer's disease - Therapeutic implications
04
7839178 2003 CURRENT MEDICINAL CHEMISTRY 10(24):2651-2659
Butterfield DA
Amyloid beta-peptide [1-42]-associated free radical-induced oxidative stress and neurodegeneration in Alzheimer's disease grain: Mechanisms and consequences
00
7958179 2003 CURRENT OPINION IN GENETICS & DEVELOPMENT 13(3):253-261
Berke SJS; Paulson HL
Protein aggregation and the ubiquitin proteasome pathway: gaining the UPPer hand on neurodegeneration
318
8057180 2003 CURRENT OPINION IN RHEUMATOLOGY 15(6):737-744
Askanas V; Engel WK
Proposed pathogenetic cascade of inclusion-body myositis: importance of amyloid-beta, misfolded proteins, predisposing genes, and aging
02
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
8148781 2003 CURRENT OPINION IN STRUCTURAL BIOLOGY 13(2):146-159
Thirumalai D; Klimov DK; Dima RI
Emerging ideas on the molecular basis of protein and peptide aggregation
213
8228382 2003 CYTOGENETIC AND GENOME RESEARCH 100(1-4):261-275
Kobayashi T; Kakizuka A
Molecular analyses of Machado-Joseph disease
03
8336483 2003 EMBO JOURNAL 22(3):355-361
Temussi PA; Masino L; Pastore A
From Alzheimer to Huntington: why is a structural understanding so difficult?
116
8413584 2003 EUROPEAN JOURNAL OF BIOCHEMISTRY 270(4):654-663
Frost D; Gorman PM; Yip CM; Chakrabartty A
Co-incorporation of A beta 40 and A beta 42 to form mixed pre-fibrillar aggregates
12
85530885 2003 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 35(11):1505-1535
Ling Y; Morgan K; Kalsheker N
Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer's disease
35
8657486 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(13):11612-11622
Stine WB; Dahlgren KN; Krafft GA; LaDu MJ
In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis
716
8727087 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(15):13047-13055
Nucifora FC; Ellerby LM; Wellington CL; Wood JD; Herring WJ; Sawa A; Hayden MR; Dawson VL; Dawson TM; Ross CA
Nuclear localization of a non-caspase truncation product of atrophin-1, with an expanded polyglutamine repeat, increases cellular toxicity
05
8856588 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(25):23187-23195
Qahwash I; Weiland KL; Lu YF; Sarver RW; Kletzien RF; Yan RQ
Identification of a mutant amyloid peptide that predominantly forms neurotoxic protofibrillar aggregates
11
8915389 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(26):23221-23226
Morelli L; Llovera R; Gonzalez SA; Affranchino JL; Prelli F; Frangione B; Ghiso J; Castano EM
Differential degradation of amyloid beta genetic variants associated with hereditary dementia or stroke by insulin-degrading enzyme
34
9042890 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(26):23648-23655
Yoshiike Y; Chui DH; Akagi T; Tanaka N; Takashima A
Specific compositions of amyloid-beta peptides as the determinant of toxic beta-aggregation
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
9125891 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(30):27971-27980
Minogue AM; Schmid AW; Fogarty MP; Moore AC; Campbell VA; Herron CE; Lynch MA
Activation of the c-Jun N-terminal kinase signaling cascade mediates the effect of amyloid-beta on long term potentiation and cell death in hippocampus - A role for interleukin-1 beta?
04
9223492 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(36):34717-34724
Tanaka M; Machida Y; Nishikawa Y; Akagi T; Hashikawa T; Fujisawa T; Nukina N
Expansion of polyglutamine induces the formation of quasi-aggregate in the early stage of protein fibrillization
01
9313893 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(37):34874-34881
Chalifour RJ; McLaughlin RW; Lavoie L; Morissette C; Tremblay N; Boule M; Sarazin P; Stea D; Lacombe D; Tremblay P; Gervais F
Stereoselective interactions of peptide inhibitors with the beta-amyloid peptide
02
9456794 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(37):34882-34889
Bitan G; Vollers SS; Teplow DB
Elucidation of primary structure elements controlling early amyloid beta-protein oligomerization
25
9514495 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(37):35317-35324
Schmechel A; Zentgraf H; Scheuermann S; Fritz G; Pipkorn RD; Reed J; Beyreuther K; Bayer TA; Multhaup G
Alzheimer beta-amyloid homodimers facilitate A beta fibrillization and the generation of conformational antibodies
00
9622496 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(39):37314-37320
Leissring MA; Lu A; Condron MM; Teplow DB; Stein RL; Farris W; Selkoe DJ
Kinetics of amyloid beta-protein degradation determined by novel fluorescence-and fluorescence polarization-based assays
11
9724797 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(42):41452-41461
Busch A; Engemann S; Lurz R; Okazawa H; Lehrach H; Wanker EE
Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin - A potential mechanism for loss of huntingtin function in Huntington's disease
04
9814898 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(43):41890-41899
Kim SJ; Sung JY; Um JW; Hattori N; Mizuno Y; Tanaka K; Paik SR; Kim J; Chung KC
Parkin cleaves intracellular alpha-synuclein inclusions via the activation of calpain
12
9926099 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(44):42959-42965
Barnham KJ; Ciccotosto GD; Tickler AK; Ali FE; Smith DG; Williamson NA; Lam YH; Carrington D; Tew D; Kocak G; Volitakis I; Separovic F; Barrow CJ; Wade JD; Masters CL; Cherny RA; Curtain CC; Bush AI; Cappai R
Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation
410
100139100 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(46):46179-46187
Murakami K; Irie K; Morimoto A; Ohigashi H; Shindo M; Nagao M; Shimizu T; Shirasawa T
Neurotoxicity and physicochemical properties of A beta mutant peptides from cerebral amyloid angiopathy - Implication for the pathogenesis of cerebral amyloid angiopathy and Alzheimer's disease
11

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