| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 1 | 1 | 1 2001 ANNUAL REVIEW OF GENETICS 35():209-241
Hakem R; Mak TW
Animal models of tumor-suppressor genes | 9 | 0
|
| 2 | 2 | 2 2001 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 1551(2):F1-F37
Zornig M; Hueber AO; Baum W; Evan G
Apoptosis regulators and their role in tumorigenesis | 24 | 2
|
| 3 | 1 | 3 2001 BIOESSAYS 23(10):947-953
Blagosklonny MV
Paradox of Bcl-2 (and p53): why may apoptosis-regulating proteins be irrelevant to cell death? | 5 | 0
|
| 4 | 1 | 4 2001 BRITISH JOURNAL OF CANCER 85(12):1813-1823
Balint E; Vousden KH
Activation and activities of the p53 tumour suppressor protein | 19 | 0
|
| 5 | 1 | 5 2001 CANCER AND METASTASIS REVIEWS 20(1-2):3-11
Grossman D; Altieri DC
Drug resistance in melanoma: Mechanisms, apoptosis, and new potential therapeutic targets | 1 | 1
|
| 6 | 2 | 6 2001 CANCER RESEARCH 61(13):5303-5306
van der Velden PA; Metzelaar-Blok JAW; Bergman W; Hurks HMH; Frants RR; Gruis NA; Jager MJ
Promoter hypermethylation: A common cause of reduced p16(INK4a) expression in uveal melanoma | 5 | 0
|
| 7 | 3 | 7 2001 CANCER RESEARCH 61(18):6660-6664
Robles AI; Bemmels NA; Foraker AB; Harris CC
APAF-1 is a transcriptional target of p53 in DNA damage-induced apoptosis | 20 | 2
|
| 8 | 1 | 8 2001 CANCER RESEARCH 61(23):8395-8400
Guo Z; Shi YK; Yoshida H; Mak TW; Zacksenhaus E
Inactivation of the retinoblastoma tumor suppressor induces apoptosis protease-activating factor-1 dependent and independent apoptotic pathways during embryogenesis | 9 | 2
|
| 9 | 2 | 9 2001 CELL DEATH AND DIFFERENTIATION 8(11):1066-1075
El-Deiry WS
Insights into cancer therapeutic design based on p53 and TRAIL receptor signaling | 7 | 0
|
| 10 | 1 | 10 2001 CURRENT OPINION IN CELL BIOLOGY 13(3):332-337
Ryan KM; Phillips AC; Vousden KH
Regulation and function of the p53 tumor suppressor protein | 73 | 5
|
| 11 | 2 | 11 2001 EUROPEAN JOURNAL OF HISTOCHEMISTRY 45(4):311-318
Steinbeck RG
Pathologic mitoses and pathology of mitosis in tumorigenesis | 1 | 0
|
| 12 | 1 | 12 2001 FEBS LETTERS 505(2):206-212
Kamarajan P; Sun NK; Sun CL; Chao CCK
Apaf-1 overexpression partially overcomes apoptotic resistance in a cisplatin-selected HeLa cell line | 5 | 0
|
| 13 | 1 | 13 2001 GENE 277(1-2):15-30
Cadwell C; Zambetti GP
The effects of wild-type p53 tumor suppressor activity and mutant p53 gain-of-function on cell growth | 4 | 0
|
| 14 | 1 | 14 2001 GENES CHROMOSOMES & CANCER 32(4):311-323
McBurney MW; Lau S; Jardine K; Yang XF; Davies B
Reexpression of a cluster of silenced transgenes is associated with their rearrangement | 1 | 0
|
| 15 | 1 | 15 2001 INTERNATIONAL JOURNAL OF CANCER 93(5):617-622
Helmbach H; Rossmann E; Kern MA; Schadendorf D
Drug-resistance in human melanoma | 11 | 2
|
| 16 | 1 | 16 2001 INTERNATIONAL JOURNAL OF CANCER 95(6):388-393
Kumar R; Smeds J; Berggren P; Straume O; Rozell BL; Akslen LA; Hemminki K
A single nucleotide polymorphism in the 3 ' untranslated region of the CDKN2A gene is common in sporadic primary melanomas but mutations in the CDKN2B, CDKN2C, CDK4 and p53 genes are rare | 8 | 0
|
| 17 | 1 | 17 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 19(3):473-488
Sinkovics JG; Horvath JC
Virological and immunological connotations of apoptotic and anti-apoptotic forces in neoplasia | 0 | 0
|
| 18 | 1 | 18 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(36):34244-34251
Wolf BB; Schuler M; Li W; Eggers-Sedlet B; Lee W; Tailor P; Fitzgerald P; Mills GB; Green DR
Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity | 12 | 8
|
| 19 | 1 | 19 2001 JOURNAL OF CELL BIOLOGY 153(5):999-1009
Foghsgaard L; Wissing D; Mauch D; Lademann U; Bastholm L; Boes M; Elling F; Leist M; Jaattela M
Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor | 51 | 1
|
| 20 | 1 | 20 2001 JOURNAL OF MOLECULAR MEDICINE-JMM 79(8):428-436
Teitz T; Lahti JM; Kidd VJ
Aggressive childhood neuroblastomas do not express caspase-8: an important component of programmed cell death | 6 | 1
|
| 21 | 2 | 21 2001 JOURNAL OF NEUROSCIENCE 21(19):7439-7446
Yakovlev AG; Ota K; Wang GP; Movsesyan V; Bao WL; Yoshihara K; Faden AI
Differential expression of apoptotic protease-activating factor-1 and caspase-3 genes and susceptibility to apoptosis during brain development and after traumatic brain injury | 14 | 2
|
| 22 | 1 | 22 2001 LANCET 358(9279):345-346
Eichhorst ST; Krammer PH
Derangement of apoptosis in cancer | 0 | 0
|
| 23 | 1 | 23 2001 MOLECULAR AND CELLULAR BIOLOGY 21(11):3684-3691
Mandic A; Viktorsson K; Molin M; Akusjarvi G; Eguchi H; Hayashi SI; Toi M; Hansson J; Linder S; Shoshan MC
Cisplatin induces the proapoptotic conformation of Bak in a Delta MEKK1-dependent manner | 10 | 0
|
| 24 | 1 | 24 2001 NATURE 409(6817):141-+
Jones PA
Cancer - Death and methylation | 16 | 9
|
| 25 | 0 | 25 2001 NATURE 409(6817):207-211
Soengas MS; Capodieci P; Polsky D; Mora J; Esteller M; Opitz-Araya X; McCombie R; Herman JG; Gerald WL; Lazebnik YA; Cordon-Cardo C; Lowe SW
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma | 147 | 147
|
| 26 | 1 | 26 2001 NATURE 411(6835):342-348
Evan GI; Vousden KH
Proliferation, cell cycle and apoptosis in cancer | 157 | 15
|
| 27 | 1 | 27 2001 NATURE CELL BIOLOGY 3(6):552-558
Moroni MC; Hickman ES; Denchi EL; Caprara G; Colli E; Cecconi F; Muller H; Helin K
Apaf-1 is a transcriptional target for E2F and p53 | 70 | 16
|
| 28 | 1 | 28 2001 NATURE REVIEWS CANCER 1(2):142-150
Hersey P; Zhang XD
How melanoma cells evade trail-induced apoptosis | 5 | 0
|
| 29 | 1 | 29 2001 NATURE REVIEWS CANCER 1(3):233-240
Soussi T; Beroud C
Assessing TP53 status in human tumours to evaluate clinical outcome | 20 | 1
|
| 30 | 2 | 30 2001 NATURE REVIEWS MOLECULAR CELL BIOLOGY 2(3):163-163
Mitchell A
Silent but deadly | 0 | 0
|
| 31 | 1 | 31 2001 NATURE STRUCTURAL BIOLOGY 8(5):394-401
Shi YG
A structural view of mitochondria-mediated apoptosis | 43 | 5
|
| 32 | 1 | 32 2001 ONCOGENE 20(36):5043-5053
Janicke RU; Engels IH; Dunkern T; Kaina B; Schulze-Osthoff K; Porter AG
Ionizing radiation but not anticancer drugs causes cell cycle arrest and failure to activate the mitochondrial death pathway in MCF-7 breast carcinoma cells | 5 | 0
|
| 33 | 1 | 33 2001 ONCOGENE 20(53):7787-7796
Zhu WG; Dai ZY; Ding HM; Srinivasan K; Hall J; Duan WR; Villalona-Calero MA; Plass C; Otterson GA
Increased expression of unmethylated CDKN2D by 5-aza-2 '- deoxycytidine in human lung cancer cells | 5 | 1
|
| 34 | 1 | 34 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(17):9683-9687
Honarpour N; Gilbert SL; Lahn BT; Wang XD; Herz J
Apaf-1 deficiency and neural tube closure defects are found in fog mice | 7 | 2
|
| 35 | 1 | 35 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(19):10833-10838
Ruefli AA; Ausserlechner MJ; Bernhard D; Sutton VR; Tainton KM; Kofler R; Smyth MJ; Johnstone RW
The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species | 9 | 2
|
| 36 | 1 | 36 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(23):13312-13317
Sotillo R; Garcia JF; Ortega S; Martin J; Dubus P; Barbacid M; Malumbres M
Invasive melanoma in Cdk4-targeted mice | 15 | 2
|
| 37 | 1 | 37 2001 TRENDS IN CELL BIOLOGY 11(8):343-+
Huang P; Oliff A
Signaling pathways in apoptosis as potential targets-for cancer therapy | 10 | 1
|
| 38 | 1 | 38 2001 TRENDS IN GENETICS 17(10):569-573
Devilee P; Cleton-Jansen AM; Cornelisse CJ
Ever since Knudson | 12 | 0
|
| 39 | 1 | 39 2001 TRENDS IN MOLECULAR MEDICINE 7(5):191-194
Satyamoorthy K; Bogenrieder T; Herlyn M
No longer a molecular black box - new clues to apoptosis and drug resistance in melanoma | 6 | 3
|
| 40 | 1 | 40 2002 ADVANCES IN CANCER RESEARCH, VOL 85 85():145-174
Ng CP; Bonavida B
A new challenge for successful immunotherapy by tumors that are resistant to apoptosis: Two complementary signals to overcome cross-resistance | 2 | 0
|
| 41 | 6 | 41 2002 ANNALS OF MEDICINE 34(6):451-469
Ding HF; Fisher DE
Induction of apoptosis in cancer: new therapeutic opportunities | 0 | 0
|
| 42 | 1 | 42 2002 ANTICANCER RESEARCH 22(2A):659-664
Jin X; Burke W; Rothman K; Lin J
Resistance to p53-mediated growth suppression in human ovarian cancer cells retain endogenous wild-type p53 | 0 | 0
|
| 43 | 1 | 43 2002 ANTICANCER RESEARCH 22(4):1959-1964
Han ZY; Ribbizi I; Pantazis P; Wyche J; Darnowski J; Calabresi P
The antibacterial drug taurolidine induces apoptosis by a mitochondrial cytochrome c-dependent mechanism | 0 | 0
|
| 44 | 2 | 44 2002 ANTICANCER RESEARCH 22(6C):4115-4120
Hsu S; Yu FS; Lewis J; Singh B; Borke J; Osaki T; Athar M; Schuster R
Induction of p57 is required for cell survival when exposed to green tea polyphenols | 0 | 0
|
| 45 | 5 | 45 2002 APOPTOSIS 7(2):167-171
Hickman ES; Helin K
The regulation of APAF1 expression during development and tumourigenesis | 0 | 0
|
| 46 | 2 | 46 2002 BIOCHIMIE 84(2-3):113-121
Waterhouse NJ; Ricci JE; Green DR
And all of a sudden it's over: mitochondrial outer-membrane permeabilization in apoptosis | 8 | 0
|
| 47 | 1 | 47 2002 BLOOD 99(1):372-374
Kratz CP; Emerling BM; Bonifas J; Wang W; Green ED; Le Beau MM; Shannon KM
Genomic structure of the PIK3CG gene on chromosome band 7q22 and evaluation as a candidate myeloid tumor suppressor | 1 | 0
|
| 48 | 2 | 48 2002 BLOOD 99(6):1885-1893
Zhang B; Gojo I; Fenton RG
Myeloid cell factor-1 is a critical survival factor for multiple myeloma | 7 | 0
|
| 49 | 1 | 49 2002 BLOOD 99(12):4540-4546
ten Berge RL; Meijer CJLM; Dukers DF; Kummer JA; Bladergroen BA; Vos W; Hack CE; Ossenkoppele GJ; Oudejans JJ
Expression levels of apoptosis-related proteins predict clinical outcome in anaplastic large cell lymphoma | 1 | 0
|
| 50 | 1 | 50 2002 BLOOD 100(1):36-42
Dukers DF; Meijer CJLM; ten Berge RL; Vos W; Ossenkoppele GJ; Oudejans JJ
High numbers of active caspase 3-positive Reed-Sternberg cells in pretreatment biopsy specimens of patients with Hodgkin disease predict favorable clinical outcome | 0 | 0
|
| 51 | 1 | 51 2002 BMC CANCER 2():art. no.-29
Yu J; Ni M; Xu J; Zhang HY; Gao BM; Gu JR; Chen JG; Zhang LS; Wu MC; Zhen SS; Zhu JD
Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis | 0 | 0
|
| 52 | 1 | 52 2002 BRITISH JOURNAL OF CANCER 86(6):893-898
Gerhard MC; Schmid RM; Hacker G
Analysis of the cytochrome c-dependent apoptosis apparatus in cells from human pancreatic carcinoma | 0 | 0
|
| 53 | 1 | 53 2002 BRITISH JOURNAL OF CANCER 87(8):924-932
Schmidt M; Hovelmann S; Beckers TL
A novel form of constitutively active farnesylated Akt I prevents mammary epithelial cells from anoikis and suppresses chemotherapy-induced apoptosis | 0 | 0
|
| 54 | 1 | 54 2002 BRITISH JOURNAL OF HAEMATOLOGY 117(2):333-342
Liu FT; Kelsey SM; Newland AC; Jia L
Liposomal encapsulation diminishes daunorubicin-induced generation of reactive oxygen species, depletion of ATP and necrotic cell death in human leukaemic cells | 6 | 1
|
| 55 | 1 | 55 2002 CANCER BIOLOGY & THERAPY 1(1):14-17
Satyamoorthy K; Herlyn M
Cellular and molecular biology of human melanoma | 1 | 0
|
| 56 | 3 | 56 2002 CANCER BIOLOGY & THERAPY 1(4):380-387
Cilensek ZM; Yehiely F; Kular RK; Deiss LP
A member of the GAGE family of tumor antigens is an anti- apoptotic gene that confers resistance to Fas/CD95/AP0-1, interferon-gamma, taxol and gamma-irradiation | 0 | 0
|
| 57 | 4 | 57 2002 CANCER CELL 1(1):19-30
Green DR; Evan GI
A matter of life and death | 35 | 2
|
| 58 | 2 | 58 2002 CANCER CELL 1(3):289-298
Schmitt CA; Fridman JS; Yang M; Baranov E; Hoffman RM; Lowe SW
Dissecting p53 tumor suppressor functions in vivo | 18 | 1
|
| 59 | 2 | 59 2002 CANCER CELL 2(4):275-278
Houghton AN; Polsky D
Focus on melanoma | 0 | 0
|
| 60 | 1 | 60 2002 CANCER CHEMOTHERAPY AND PHARMACOLOGY 49(2):167-175
Quto SS; Ng CE
Comparison of apoptotic, necrotic and clonogenic cell death and inhibition of cell growth following camptothecin and X- radiation treatment in a human melanoma and a human fibroblast cell line | 0 | 0
|
| 61 | 2 | 61 2002 CANCER LETTERS 185(2):181-189
Wotawa A; Solier S; Logette E; Solary E; Corcos L
Differential influence of etoposide on two caspase-2 mRNA isoforms in leukemic cells | 3 | 0
|
| 62 | 1 | 62 2002 CANCER RESEARCH 62(3):924-931
Liu JR; Opipari AW; Tan LJ; Jiang YB; Zhang YJ; Tang HJ; Nunez G
Dysfunctional apoptosome activation in ovarian cancer: Implications for chemoresistance | 9 | 4
|
| 63 | 1 | 63 2002 CANCER RESEARCH 62(4):961-966
Liang G; Gonzales FA; Jones PA; Orntoft TF; Thykjaer T
Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2 '- deoxycytidine | 11 | 2
|
| 64 | 2 | 64 2002 CANCER RESEARCH 62(6):1648-1653
Torok NJ; Higuchi H; Bronk S; Gores GJ
Nitric oxide inhibits apoptosis downstream of cytochrome c release by nitrosylating caspase 9 | 4 | 0
|
| 65 | 2 | 65 2002 CANCER RESEARCH 62(16):4685-4689
Machover D; Zittoun J; Saffroy R; Broet P; Giraudier S; Magnaldo T; Goldschmidt E; Debuire B; Orrico M; Tan YY; Mishal Z; Chevallier O; Tonetti C; Jouault H; Ulusakarya A; Tanguy ML; Metzger G; Hoffman RM
Treatment of cancer cells with methioninase produces DNA hypomethylation and increases DNA synthesis | 0 | 0
|
| 66 | 3 | 66 2002 CANCER RESEARCH 62(20):5920-5929
Neef R; Kuske MA; Prols E; Johnson JP
Identification of the human PHLDA1/TDAG51 gene: Down-regulation in metastatic melanoma contributes to apoptosis resistance and growth deregulation | 0 | 0
|
| 67 | 6 | 67 2002 CELL 108(2):153-164
Johnstone RW; Ruefli AA; Lowe SW
Apoptosis: A link between cancer genetics and chemotherapy | 58 | 6
|
| 68 | 1 | 68 2002 CELL 109():S97-S107
Rathmell JC; Thompson CB
Pathways of apoptosis in lymphocyte development, homeostasis, and disease | 14 | 1
|
| 69 | 4 | 69 2002 CELL DEATH AND DIFFERENTIATION 9(2):96-98
Pru JK; Tilly JL
Genomic plasticity in cell death susceptibility | 0 | 0
|
| 70 | 3 | 70 2002 CURRENT OPINION IN CELL BIOLOGY 14(6):715-720
Adams JM; Cory S
Apoptosomes: engines for caspase activation | 0 | 0
|
| 71 | 2 | 71 2002 CURRENT OPINION IN GENETICS & DEVELOPMENT 12(1):60-66
Hickman ES; Moroni MC; Helin K
The role of p53 and pRB in apoptosis and cancer | 6 | 0
|
| 72 | 1 | 72 2002 EXPERT OPINION ON INVESTIGATIONAL DRUGS 11(1):75-85
Hersey P
Advances in the non-surgical treatment of melanoma | 2 | 0
|
| 73 | 1 | 73 2002 GENES & DEVELOPMENT 16(1):33-45
Deng YB; Lin YH; Wu XW
TRAIL-induced apoptosis requires Bax-dependent mitochondria release of Smac/DIABLO | 39 | 2
|
| 74 | 2 | 74 2002 INTERNATIONAL JOURNAL OF CANCER 98(3):323-330
Bush JA; Li G
Cancer chemoresistance: the relationship between p53 and multidrug transporters | 5 | 0
|
| 75 | 2 | 75 2002 INTERNATIONAL JOURNAL OF CANCER 100(5):615-617
Middleton MR; Thatcher N; McMurry TBH; McElhinney RS; Donnelly DJ; Margison GP
Effect of O-6-(4-bromothenyl)guanine on different temozolomide schedules in a human melanoma xenograft model | 0 | 0
|
| 76 | 1 | 76 2002 INTERNATIONAL JOURNAL OF HYPERTHERMIA 18(2):153-164
Wachsberger PR; Burd R; Wahl ML; Leeper DB
Betulinic acid sensitization of low pH adapted human melanoma cells to hyperthermia | 0 | 0
|
| 77 | 1 | 77 2002 INTERNATIONAL JOURNAL OF ONCOLOGY 20(6):1319-1322
Cheung KJ; Li G
The tumour suppressor p33(ING1) does not enhance camptothecin- induced cell death in melanoma cells | 0 | 0
|
| 78 | 2 | 78 2002 JOURNAL OF BIOCHEMISTRY 131(1):131-135
Ota K; Yakovlev AG; Itaya A; Kameoka M; Tanaka Y; Yoshihara K
Alteration of apoptotic protease-activating factor-1 (APAF-1)- dependent apoptotic pathway during development of rat brain and liver | 0 | 0
|
| 79 | 1 | 79 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(4):2790-2797
Mochizuki T; Asai A; Saito N; Tanaka S; Katagiri H; Asano T; Nakane M; Tamura A; Kuchino Y; Kitanaka C; Kirino T
Akt protein kinase inhibits non-apoptotic programmed cell death induced by ceramide | 5 | 0
|
| 80 | 1 | 80 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(7):4932-4944
Ivanov VN; Krasilnikov M; Ronai Z
Regulation of Fas expression by STAT3 and c-Jun is mediated by phosphatidylinositol 3-kinase-AKT signaling | 4 | 0
|
| 81 | 1 | 81 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(13):11345-11351
Sun XM; Bratton SB; Butterworth M; MacFarlane M; Cohen GM
Bcl-2 and Bcl-x(L) inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein | 16 | 0
|
| 82 | 2 | 82 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(31):27643-27650
Gilmore AP; Valentijn AJ; Wang PB; Ranger AM; Bundred N; O'Hare MJ; Wakeling A; Korsmeyer SJ; Streuli CH
Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor | 7 | 0
|
| 83 | 2 | 83 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(42):39760-39768
Furukawa Y; Nishimura N; Furukawa Y; Satoh M; Endo H; Iwase S; Yamada H; Matsuda M; Kano Y; Nakamura M
Apaf-1 is a mediator of E2F-1-induced apoptosis | 2 | 0
|
| 84 | 1 | 84 2002 JOURNAL OF DERMATOLOGICAL SCIENCE 29(3):159-165
Nickoloff BJ
Cutaneous dendritic cells in the crossfire between innate and adaptive immunity | 0 | 0
|
| 85 | 1 | 85 2002 JOURNAL OF IMMUNOLOGY 169(2):847-855
Chawla-Sarkar M; Leaman DW; Jacobs BS; Borden EC
IFN-beta pretreatment sensitizes human melanoma cells to TRAIL/Apo2 ligand-induced apoptosis | 0 | 0
|
| 86 | 2 | 86 2002 JOURNAL OF INVESTIGATIVE DERMATOLOGY 118(6):923-932
Helmbach H; Kern MA; Rossmann E; Renz K; Kissel C; Gschwendt B; Schadendorf D
Drug resistance towards etoposide and cisplatin in human melanoma cells is associated with drug-dependent apoptosis deficiency | 2 | 0
|
| 87 | 2 | 87 2002 JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS 7(1):17-26
Dlugosz A; Merlino G; Yuspa SH
Progress in cutaneous cancer research | 0 | 0
|
| 88 | 1 | 88 2002 JOURNAL OF LEUKOCYTE BIOLOGY 71(6):907-920
Igney FH; Krammer PH
Immune escape of tumors: apoptosis resistance and tumor counterattack | 3 | 0
|
| 89 | 1 | 89 2002 JOURNAL OF ORAL PATHOLOGY & MEDICINE 31(3):125-133
Whyte DA; Broton CE; Shillitoe EJ
The unexplained survival of cells in oral cancer: what is the role of p53? | 0 | 0
|
| 90 | 3 | 90 2002 JOURNAL OF PEPTIDE SCIENCE 8(10):543-560
Salgado J; Garcia-Saez AJ; Malet G; Mingarro I; Perez-Paya E
Peptides in apoptosis research | 0 | 0
|
| 91 | 1 | 91 2002 JOURNAL OF VIROLOGY 76(9):4547-4558
Cuconati A; Degenhardt K; Sundararajan R; Anschel A; White E
Bak and Bax function to limit adenovirus replication through apoptosis induction | 4 | 0
|
| 92 | 3 | 92 2002 M S-MEDECINE SCIENCES 18(8-9):861-873
Salary E; Bettaieb A; Dubrez-Daloz L; Garrido C
Alteration of cell death-related genes in human diseases | 0 | 0
|
| 93 | 1 | 93 2002 MELANOMA RESEARCH 12(1):3-8
Herlyn M
Emerging concepts and technologies in melanoma research | 1 | 0
|
| 94 | 1 | 94 2002 MELANOMA RESEARCH 12(6):523-528
Furukawa H; Fujita H; Kokubu I; Yamamoto Y; Sasaki S; Chodon T; Okubo Y; Sugihara T; Kuzumaki N
Identification of a novel gelsolin truncate in the vertical and metastatic phase malignant melanomas | 0 | 0
|
| 95 | 2 | 95 2002 MOLECULAR CANCER THERAPEUTICS 1(9):679-686
Cui HJ; Schroering A; Ding HF
p53 mediates DNA damaging drug-induced apoptosis through a caspase-9-dependent pathway in SH-SY5Y neuroblastoma cells | 0 | 0
|
| 96 | 2 | 96 2002 MOLECULAR CELL 9(3):459-470
Shi YG
Mechanisms of caspase activation and inhibition during apoptosis | 43 | 4
|
| 97 | 1 | 97 2002 MOLECULAR GENETICS AND METABOLISM 75(1):1-16
Fruhwald MC; Plass C
Global and gene-specific methylation patterns in cancer: Aspects of tumor biology and clinical potential | 3 | 0
|
| 98 | 1 | 98 2002 NATURE GENETICS 31(2):141-149
Suzuki H; Gabrielson E; Chen W; Anbazhagan R; van Engeland M; Weijenberg MP; Herman JG; Baylin SB
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer | 14 | 0
|
| 99 | 1 | 99 2002 NATURE GENETICS 32(2):306-311
Bernal JA; Luna R; Espina A; Lazaro I; Ramos-Morales F; Romero F; Arias C; Silva A; Tortolero M; Pintor-Toro JA
Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis | 1 | 0
|
| 100 | 2 | 100 2002 NATURE MEDICINE 8(3):216-218
Roth W; Reed JC
Apoptosis and cancer: When BAX is TRAILing away | 2 | 0
|
| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 101 | 3 | 101 2002 NATURE REVIEWS CANCER 2(4):277-288
Igney FH; Krammer PH
Death and anti-death: Tumour resistance to apoptosis | 18 | 2
|
| 102 | 6 | 102 2002 NATURE REVIEWS CANCER 2(8):594-604
Vousden KH; Lu X
Live or let die: The cell's response to p53 | 16 | 1
|
| 103 | 1 | 103 2002 NATURE REVIEWS CANCER 2(10):727-739
Kerbel R; Folkman J
Clinical translation of angiogenesis inhibitors | 12 | 0
|
| 104 | 2 | 104 2002 NATURE REVIEWS DRUG DISCOVERY 1(4):287-299
Johnstone RW
Histone-deacetylase inhibitors: Novel drugs for the treatment of cancer | 16 | 0
|
| 105 | 2 | 105 2002 NATURE REVIEWS GENETICS 3(6):415-428
Jones PA; Baylin SB
The fundamental role of epigenetic events in cancer | 60 | 2
|
| 106 | 3 | 106 2002 NATURE REVIEWS MOLECULAR CELL BIOLOGY 3(10):779-787
Baehrecke EH
How death shapes life during development | 2 | 0
|
| 107 | 1 | 107 2002 NEOPLASIA 4(3):218-227
Basu A; Das M; Qanungo S; Fan CJ; DuBois G; Haldar S
Proteasomal degradation of human peptidyl prolyl isomerase Pin1-pointing phospho Bcl2 toward dephosphorylation | 3 | 0
|
| 108 | 2 | 108 2002 ONCOGENE 21(1):1-8
Wu GS; Ding ZH
Caspase 9 is required for p53-dependent apoptosis and chemosensitivity in a human ovarian cancer cell line | 4 | 0
|
| 109 | 1 | 109 2002 ONCOGENE 21(12):1848-1858
Teitz T; Wei T; Liu D; Valentine V; Valentine M; Grenet J; Lahti JM; Kidd VJ
Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN | 2 | 2
|
| 110 | 1 | 110 2002 ONCOGENE 21(26):4149-4157
Qanungo S; Basu A; Das M; Haldar S
2-methoxyestradiol induces mitochondria dependent apoptotic signaling in pancreatic cancer cells | 2 | 0
|
| 111 | 2 | 111 2002 ONCOGENE 21(35):5427-5440
Esteller M
CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future | 4 | 0
|
| 112 | 2 | 112 2002 ONCOGENE 21(35):5462-5482
Widschwendter M; Jones PA
DNA methylation and breast carcinogenesis | 1 | 0
|
| 113 | 2 | 113 2002 ONCOGENE 21(42):6498-6509
Santoni-Rugiu E; Duro D; Farkas T; Mathiasen IS; Jaattela M; Bartek J; Lukas J
E2F activity is essential for survival of Myc-overexpressing human cancer cells | 1 | 0
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| 114 | 1 | 114 2002 ONCOGENE 21(49):7497-7506
Winn RA; Bremnes RM; Bemis L; Franklin WA; Miller YE; Cool C; Heasley LE
gamma-Catenin expression is reduced or absent in a subset of human lung cancers and re-expression inhibits transformed cell growth | 0 | 0
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| 115 | 2 | 115 2002 ONCOGENE 21(57):8786-8803
Debatin KM; Poncet D; Kroemer G
Chemotherapy: targeting the mitochondrial cell death pathway | 0 | 0
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| 116 | 2 | 116 2002 ONCOGENE 21(57):8843-8851
Devarajan E; Sahin AA; Chen JS; Krishnamurthy RR; Aggarwal N; Brun AM; Sapino A; Zhang F; Sharma D; Yang XH; Tora AD; Mehta K
Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance | 0 | 0
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| 117 | 2 | 117 2002 PHARMACOGENOMICS 3(5):603-623
Mellinghoff IK; Sawyers CL
The emergence of resistance to targeted cancer therapeutics | 0 | 0
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| 118 | 2 | 118 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(7):4197-4202
Shiozaki EN; Chai JJ; Shi Y
Oligomerization and activation of caspase-9, induced by Apaf-1 CARD | 1 | 0
|
| 119 | 1 | 119 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(9):6136-6141
Liu TX; Zhou Y; Kanki JP; Deng M; Rhodes J; Yang HW; Sheng XM; Zon LI; Look AT
Evolutionary conservation of zebrafish linkage group 14 with frequently deleted regions of human chromosome 5 in myeloid malignancies | 2 | 0
|
| 120 | 1 | 120 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(14):9433-9438
Smith G; Carey FA; Beattie J; Wilkie MJV; Lightfoot TJ; Coxhead J; Garner RC; Steele RJC; Wolf CR
Mutations in APC, Kirsten-ras, and p53 - alternative genetic pathways to colorectal cancer | 3 | 0
|
| 121 | 3 | 121 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(14):9492-9497
MacLachan TK; El-Deiry WS
Apoptotic threshold is lowered by p53 transactivation of caspase-6 | 1 | 0
|
| 122 | 1 | 122 2002 REPRODUCTION 123(3):341-353
Liu Y; Ganesan TS
Tumour suppressor genes in sporadic epithelial ovarian cancer | 2 | 0
|
| 123 | 4 | 123 2002 TRENDS IN MOLECULAR MEDICINE 8(5):212-220
Mathiasen IS; Jaattela M
Triggering caspase-independent cell death to combat cancer | 3 | 0
|
| 124 | 1 | 124 2003 ANTICANCER RESEARCH 23(1A):99-105
Luu Y; Li G
The p53-stabilizing compound, CP-31398, does not enhance chemosensitivity in human melanoma cells | 0 | 0
|
| 125 | 2 | 125 2003 APOPTOSIS 8(1):5-9
Watari A; Yutsudo M
Multi-functional gene ASY/Nogo/RTN-X/RTN4: Apoptosis, tumor suppression, and inhibition of neuronal regeneration | 0 | 0
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| 126 | 4 | 126 2003 BULLETIN DU CANCER 90(1):9-17
Segal-Bendirdjian E; Hillion J; Belmokhtar CA
Current concepts on apoptotic signalling pathways: new targets for anticancer strategies | 0 | 0
|
| 127 | 3 | 127 2003 CANCER RESEARCH 63(4):831-837
Yang LL; Mashima T; Sato S; Mochizuki M; Sakamoto H; Yamori T; Oh-hara T; Tsuruo T
Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: Therapeutic effect of a novel polyarginine-conjugated Smac peptide | 0 | 0
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| 128 | 2 | 128 2003 CANCER RESEARCH 63(7):1639-1643
Spugnardi M; Tommasi S; Dammann R; Pfeifer GP; Hoon DSB
Epigenetic inactivation of RAS Association Domain Family Protein 1 (RASSF1A) in malignant cutaneous melanoma | 0 | 0
|
| 129 | 1 | 129 2003 CANCER RESEARCH 63(7):1712-1721
Kandasamy K; Srinivasula SM; Alnemri ES; Thompson CB; Korsmeyer SJ; Bryant JL; Srivastava RK
Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)- induced mitochondrial disruption and apoptosis: Differential regulation of cytochrome c and Smac/DIABLO release | 0 | 0
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| 130 | 5 | 130 2003 CELL STRUCTURE AND FUNCTION 28(1):3-9
Yoshida H
The role of Apaf-1 in programmed cell death: From worm to tumor | 0 | 0
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| 131 | 1 | 131 2003 CURRENT SCIENCE 84(3):430-434
Gope ML; Gope R
Effect of sodium butyrate on methylation pattern of retinoblastoma (RB1) gene in human colon tumour cell line HT29 | 0 | 0
|
| 132 | 2 | 132 2003 GENES & DEVELOPMENT 17(5):629-637
Kennedy NJ; Sluss HK; Jones SN; Bar-Sagi D; Flavell RA; Davis RJ
Suppression of Ras-stimulated transformation by the JNK signal transduction pathway | 0 | 0
|
| 133 | 1 | 133 2003 HUMAN MOLECULAR GENETICS 12(7):791-801
Dai ZY; Zhu WG; Morrison CD; Brena RM; Smiraglia DJ; Raval A; Wu YZ; Rush LJ; Ross P; Molina JR; Otterson GA; Plass C
A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes | 0 | 0
|
| 134 | 1 | 134 2003 INTERNATIONAL JOURNAL OF CANCER 104(5):527-532
Smalley KSM
A pivotal role for ERK in the oncogenic behaviour of malignant melanoma? | 0 | 0
|
| 135 | 2 | 135 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(10):8238-8243
Flynn J; Fang JY; Mikovits JA; Reich NO
A potent cell-active allosteric inhibitor of murine DNA cytosine C-5 methyltransferase | 0 | 0
|
| 136 | 4 | 136 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(14):12579-12589
Henderson C; Mizzau M; Paroni G; Maestro R; Schneider C; Brancolini C
Role of caspases, bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) suberoylanilide hydroxamic acid and (SAHA) | 0 | 0
|
| 137 | 5 | 137 2003 JOURNAL OF CELLULAR BIOCHEMISTRY 88(5):885-898
Shivapurkar N; Reddy J; Chaudhary PM; Gazdar AF
Apoptosis and lung cancer: A review | 0 | 0
|
| 138 | 4 | 138 2003 JOURNAL OF INVESTIGATIVE DERMATOLOGY 120(1):48-55
Bowen AR; Hanks AN; Allen SM; Alexander A; Diedrich MJ; Grossman D
Apoptosis regulators and responses in human melanocytic and keratinocytic cells | 0 | 0
|
| 139 | 2 | 139 2003 JOURNAL OF INVESTIGATIVE DERMATOLOGY 120(4):648-654
Pennati M; Binda M; Colella G; Folini M; Citti L; Villa R; Daidone MG; Zaffaroni N
Radiosensitization of human melanoma cells by ribozyme-mediated inhibition of survivin expression | 0 | 0
|
| 140 | 1 | 140 2003 JOURNAL OF ORGANIC CHEMISTRY 68(7):2760-2764
Saravanan P; Corey EJ
A short, stereocontrolled, and practical synthesis of alpha- methylomuralide, a potent inhibitor of proteasome function | 0 | 0
|
| 141 | 2 | 141 2003 JOURNAL OF PATHOLOGY 199(3):275-288
Hussein MR; Haemel AK; Wood GS
Apoptosis and melanoma: molecular mechanisms | 0 | 0
|
| 142 | 2 | 142 2003 LANCET ONCOLOGY 4(3):177-185
Lonning PE
Study of suboptimum treatment response: lessons from breast cancer | 0 | 0
|
| 143 | 1 | 143 2003 MOLECULAR AND CELLULAR BIOLOGY 23(1):206-215
Kondo Y; Shen LL; Issa JPJ
Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer | 0 | 0
|
| 144 | 1 | 144 2003 MOLECULAR ENDOCRINOLOGY 17(4):600-609
Horwitz GA; Miklovsky I; Heaney AP; Ren SG; Melmed S
Human pituitary tumor-transforming gene (PTTG1) motif suppresses prolactin expression | 0 | 0
|
| 145 | 4 | 145 2003 ONCOGENE 22(3):451-455
Fu WN; Bertoni F; Kelsey SM; McElwaine SM; Cotter FE; Newland AC; Jia L
Role of DNA methylation in the suppression of Apaf-1 protein in human leukaemia | 0 | 0
|
| 146 | 3 | 146 2003 PLASTIC AND RECONSTRUCTIVE SURGERY 111(4):1481-1496
Gastman BR; Futrell JW; Manders EK
Apoptosis and plastic surgery | 0 | 0
|
| 147 | 1 | 147 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(7):4173-4178
Thiebault K; Mazelin L; Pays L; Llambi F; Joly MO; Scoazec JY; Saurin JC; Romeo G; Mehlen P
The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment | 0 | 0
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| 148 | 2 | 148 2003 RADIATION RESEARCH 159(3):328-335
Burd R; Lavorgna SN; Daskalakis C; Wachsberger PR; Wahl ML; Biaglow JE; Stevens CW; Leeper DB
Tumor oxygenation and acidification are increased in melanoma xenografts after exposure to hyperglycemia and meta-iodo- benzylguanidine | 0 | 0
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