Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIR1 in mediating auxin response
Schwechheimer C, Serino G, Callis J, Crosby WL, Lyapina S, Deshaies RJ, Gray WM, Estelle M, Deng XW
SCIENCE
292 (5520): 1379-1382 MAY 18 2001
and the citing papers.

#	Cited nodes	Nodes / Authors	GCS	LCS
1	1	1 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(4):876-882 Schmidt LS; Warren MB; Nickerson ML; Weirich G; Matrosova V; Toro JR; Turner ML; Duray P; Merino M; Hewitt S; Pavlovich CP; Glenn G; Greenberg CR; Linehan WM; Zbar B Birt-Hogg-Dube syndrome, a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia, maps to chromosome 17p11.2	22	0
2	2	2 2001 CURRENT BIOLOGY 11(16):R643-R646 Seeger M; Gordon C; Dubiel W Protein stability: The COP9 signalosome gets in on the act	9	3
3	1	3 2001 CURRENT OPINION IN PLANT BIOLOGY 4(5):382-386 Leyser O Auxin signalling: the beginning, the middle and the end	18	4
4	1	4 2001 CURRENT OPINION IN PLANT BIOLOGY 4(6):478-487 Assaad FF Of weeds and men: what genomes teach us about plant cell biology	7	1
5	4	5 2001 DEVELOPMENTAL CELL 1(5):595-604 Rogg LE; Bartel B Auxin signaling: Derepression through regulated proteolysis	11	2
6	1	6 2001 FASEB JOURNAL 15(13):U221-U238 Lu CR; Li Y; Zhao YL; Xing GC; Tang F; Wang QM; Sun YH; Wei HD; Yang XM; Wu CS; Chen JG; Guan KL; Zhang CG; Chen HP; He FC Intracrine hepatopoietin potentiates AP-1 activity through JAB1 independent of MAPK pathway	0	0
7	2	7 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(44):40998-41004 Wilson MP; Sun Y; Cao L; Majerus PW Inositol 1,3,4-trisphosphate 5/6-kinase is a protein kinase that phosphorylates the transcription factors c-Jun and ATF-2	9	5
8	2	8 2001 JOURNAL OF PLANT GROWTH REGULATION 20(3):195-197 Jones AM Keeping the momentum in auxin research	0	0
9	1	9 2001 JOURNAL OF PLANT GROWTH REGULATION 20(3):255-264 Chen JG Dual auxin signaling pathways control cell elongation and division	4	0
10	2	10 2001 JOURNAL OF PLANT GROWTH REGULATION 20(3):265-273 Ward SP; Estelle M Auxin signaling involves regulated protein degradation by the ubiquitin-proteasome pathway	6	2
11	3	11 2001 JOURNAL OF PLANT GROWTH REGULATION 20(3):274-280 Tian Q; Reed JW Molecular links between light and auxin signaling pathways	4	0
12	1	12 2001 JOURNAL OF PLANT GROWTH REGULATION 20(3):281-291 Guilfoyle TJ; Hagen G Auxin response factors	4	1
13	1	13 2001 PLANT CELL 13(9):1983-1986 Okamoto H; Qu L; Deng XW Does EID1 aid the fine-tuning of phytochrome A signal transduction in Arabidopsis?	1	1
14	3	14 2001 PLANT CELL 13(10):2161-2163 Eckardt NA Auxin and the power of the proteasome in plants	0	0
15	1	15 2001 PLANT CELL 13(10):2349-2360 Ramos JA; Zenser N; Leyser O; Callis J Rapid degradation of auxin/indoleacetic acid proteins requires conserved amino acids of domain II and is proteasome dependent	25	10
16	2	16 2001 PLANT CELL 13(11):2393-2407 Peng ZH; Serino G; Deng XW Molecular characterization of subunit 6 of the COP9 signalosome and its role in multifaceted developmental processes in Arabidopsis	14	12
17	1	17 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(20):11795-11800 Zenser N; Ellsmore A; Leasure C; Callis J Auxin modulates the degradation rate of Aux/IAA proteins	23	12
18	4	18 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(24):14162-14167 Dill A; Jung HS; Sun TP The DELLA motif is essential for gibberellin-induced degradation of RGA	31	3
19	1	19 2001 SCIENCE 292(5520):1379-1382 Schwechheimer C; Serino G; Callis J; Crosby WL; Lyapina S; Deshaies RJ; Gray WM; Estelle M; Deng XW Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIR1 in mediating auxin response	119	119
20	1	20 2001 SCIENCE 292(5520):1382-1385 Lyapina S; Cope G; Shevchenko A; Serino G; Tsuge T; Zhou CS; Wolf DA; Wei N; Shevchenko A; Deshaies RJ Promotion of NEDD8-CUL1 conjugate cleavage by COP9 signalosome	122	78
21	3	21 2001 TRENDS IN CELL BIOLOGY 11(10):420-426 Schwechheimer C; Deng XW COP9 signalosome revisited: a novel mediator of protein degradation	59	28
22	2	22 2001 TRENDS IN PLANT SCIENCE 6(8):379-386 Kim TH; Hofmann K; von Arnim AG; Chamovitz DA PCI complexes: pretty complex interactions in diverse signaling pathways	25	10
23	2	23 2001 TRENDS IN PLANT SCIENCE 6(9):420-425 Reed JW Roles and activities of Aux/IAA proteins in Arabidopsis	35	9
24	1	24 2001 TRENDS IN PLANT SCIENCE 6(10):463-470 Bachmair A; Novatchkova M; Potuschak T; Eisenhaber F Ubiquitylation in plants: a post-genomic look at a post- translational modification	27	7
25	2	25 2002 ADVANCES IN IMMUNOLOGY, VOL 80 80():1-70 Rock KL; York IA; Saric T; Goldberg AL Protein degradation and the generation of MHC class I-presented peptides	18	0
26	1	26 2002 ANNUAL REVIEW OF PLANT BIOLOGY 53():329-355 Nagy F; Schafer E Phytochromes control photomorphogenesis by differentially regulated, interacting signaling pathways in higher plants	20	3
27	4	27 2002 ANNUAL REVIEW OF PLANT BIOLOGY 53():377-398 Leyser O Molecular genetics of auxin signaling	12	2
28	2	28 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 290(1):1-10 Hasselgren PO; Wray C; Mammen J Molecular regulation of muscle cachexia: It may be more than the proteasome	15	0
29	5	29 2002 BMC CELL BIOLOGY 3():art. no.-30 Yi CL; Wang HY; Wei N; Deng XW An initial biochemical and cell biological characterization of the mammalian homologue of a central plant developmental switch, COP1	0	0
30	5	30 2002 BMC GENETICS 3():art. no.-15 Wee S; Hetfeld B; Dubiel W; Wolf DA Conservation of the COP9/signalosome in budding yeast	8	0
31	2	31 2002 CHINESE SCIENCE BULLETIN 47(18):1497-1501 Wang HY; Huang J; Lai Z; Xue YB F-box proteins in flowering plants	0	0
32	3	32 2002 CURRENT BIOLOGY 12(10):R352-R354 Gray WM Plant defence: A new weapon in the arsenal	2	0
33	2	33 2002 CURRENT BIOLOGY 12(8):667-672 Yang XM; Menon S; Lykke-Andersen K; Tsuge T; Xiao D; Wang XP; Rodriguez-Suarez RJ; Zhang H; Wei N The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1	17	11
34	2	34 2002 CURRENT OPINION IN CELL BIOLOGY 14(2):180-188 Quail PH Photosensory perception and signalling in plant cells: new paradigms?	20	2
35	5	35 2002 DEVELOPMENT 129(19):4399-4409 Oron E; Mannervik M; Rencus S; Harari-Steinberg O; Neuman-Silberberg S; Sega D; Chamovitz DA COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster	8	4
36	2	36 2002 DEVELOPMENTAL BIOLOGY 251(2):333-347 Smith P; Leung-Chiu WM; Montgomery R; Orsborn A; Kuznicki K; Gressman-Coberly E; Mutapcic L; Bennett K The GLH proteins, Caenorhabditis elegans P granule components, associate with CSN-5 and KGB-1, proteins necessary for fertility, and with ZYX-1, a predicted cytoskeletal protein	1	1
37	2	37 2002 EMBO REPORTS 3(2):171-176 Wan M; Cao XS; Wu YL; Bai ST; Wu LY; Shi XM; Wang N; Cao X Jab1 antagonizes TGF-beta signaling by inducing Smad4 degradation	14	1
38	2	38 2002 EMBO REPORTS 3(2):177-182 Ohh M; Kim WY; Moslehi JJ; Chen YZ; Chau V; Read MA; Kaelin WG An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells	22	5
39	9	39 2002 EMBO REPORTS 3(11):1042-1048 Schafer E; Bowler C Phytochrome-mediated photoperception and signal transduction in higher plants	2	0
40	4	40 2002 FEBS LETTERS 527(1-3):15-21 Alves KH; Bochard V; Rety S; Jalinot P Association of the mammalian proto-oncoprotein Int-6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome	3	1
41	5	41 2002 GENE 298(2):109-119 Lier S; Paululat A The proteasome regulatory particle subunit Rpn6 is required for Drosophila development and interacts physically with signalosome subunit Alien/CSN2	3	0
42	3	42 2002 GENES & DEVELOPMENT 16(5):554-559 Suzuki G; Yanagawa Y; Kwok SF; Matsui M; Deng XW Arabidopsis COP10 is a ubiquitin-conjugating enzyme variant that acts together with COP1 and the COP9 signalosome in repressing photomorphogenesis	15	12
43	1	43 2002 GENES & DEVELOPMENT 16(10):1247-1259 Holm M; Ma LG; Qu LJ; Deng XW Two interacting bZIP proteins are direct targets of COP1- mediated control of light-dependent gene expression in Arabidopsis	16	8
44	2	44 2002 GENES & DEVELOPMENT 16(17):2207-2212 Ritchie KJ; Malakhov MP; Hetherington CJ; Zhou LM; Little MT; Malakhova OA; Sipe JC; Orkin SH; Zhang DE Dysregulation of protein modification by ISG15 results in brain cell injury	5	1
45	1	45 2002 GENES & DEVELOPMENT 16(18):2403-2414 Ou CY; Lin YF; Chen YJ; Chien CT Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development	9	3
46	5	46 2002 IMMUNOLOGICAL REVIEWS 186():189-207 Rossetti G; Collinge M; Bender JR; Molteni R; Pardi R Integrin-dependent regulation of gene expression in leukocytes	2	0
47	12	47 2002 INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 220 220():185-223 Kim TH; Kim BH; von Arnim AG Repressors of photomorphogenesis	3	0
48	2	48 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(1):516-527 Wu K; Chen A; Tan PL; Pan ZQ The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34	17	7
49	2	49 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(3):2302-2310 Tomoda K; Kubota Y; Arata Y; Mori S; Maeda M; Tanaka T; Yoshida M; Yoneda-Kato N; Kato JY The cytoplasmic shuttling and subsequent degradation of p27(Kip1) mediated by Jab1/CSN5 and the COP9 signalosome complex	23	7
50	3	50 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(26):23253-23259 Amir RE; Iwai K; Ciechanover A The NEDD8 pathway is essential for SCF beta-TrCp-mediated ubiquitination and processing of the NF-kappa B precursor p105	3	1
51	7	51 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(48):45759-45764 Sun Y; Wilson MP; Majerus PW Inositol 1,3,4-trisphosphate 5/6-kinase associates with the COP9 signalosome by binding to CSN1	5	5
52	4	52 2002 JOURNAL OF CELL SCIENCE 115(3):467-473 Bech-Otschir D; Seeger M; Dubiel W The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis	18	0
53	4	53 2002 MOLECULAR BIOLOGY OF THE CELL 13(2):646-655 Wang XP; Kang DM; Feng SH; Serino G; Schwechheimer C; Wei N CSN1N-terminal-dependent activity is required for arabidopsis development but not for Rub1/Nedd8 deconjugation of cullins: A structure-function study of CSN1 subunit of COP9 signalosome	7	7
54	4	54 2002 MOLECULAR BIOLOGY OF THE CELL 13(6):1916-1928 Shen WH; Parmentier Y; Hellmann H; Lechner E; Dong AW; Masson J; Granier F; Lepiniec L; Estelle M; Genschik P Null mutation of AtCUL1 causes arrest in early embryogenesis in Arabidopsis	16	7
55	2	55 2002 MOLECULAR ENDOCRINOLOGY 16(2):315-330 Fan MY; Long XH; Bailey JA; Reed CA; Osborne E; Gize EA; Kirk EA; Bigsby RM; Nephew KP The activating enzyme of NEDD8 inhibits steroid receptor function	6	1
56	3	56 2002 NATURE REVIEWS MOLECULAR CELL BIOLOGY 3(2):85-93 Quail PH Phytochrome photosensory signalling networks	40	4
57	3	57 2002 NEURON 33(1):35-46 Suh GSB; Poeck B; Chouard T; Oron E; Segal D; Chamovitz DA; Zipursky SL Drosophila JAB1/CSN5 acts in photoreceptor cells to induce glial cells	16	8
58	2	58 2002 NEW PHYTOLOGIST 154(3):553-590 Moller SG; Ingles PJ; Whitelam GC The cell biology of phytochrome signalling	7	1
59	2	59 2002 ONCOGENE 21(22):3507-3516 Gemmill RM; Bemis LT; Lee JP; Sozen MA; Baron A; Zeng C; Erickson PF; Hooper JE; Drabkin HA The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway	3	0
60	6	60 2002 PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY 61(2):73-76 Peart JR; Shirasu K "To degrade or not to degrade?" - the emerging question in plant disease resistance	3	2
61	6	61 2002 PHYSIOLOGICAL REVIEWS 82(2):373-428 Glickman MH; Ciechanover A The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction	114	2
62	6	62 2002 PLANT CELL 14():S5-S8 Dodds PN; Schwechheimer C A breakdown in defense signaling	3	0
63	1	63 2002 PLANT CELL 14(1):17-32 Smalle J; Kurepa J; Yang PZ; Babiychuk E; Kushnir S; Durski A; Vierstra RD Cytokinin growth responses in Arabidopsis involve the 26S proteasome subunit RPN12	21	6
64	6	64 2002 PLANT CELL 14():S81-S95 Kepinski S; Leyser O Ubiquitination and auxin signaling: A degrading story	12	3
65	3	65 2002 PLANT CELL 14(7):1483-1496 Liu Y; Schiff M; Serino G; Deng XW; Dinesh-Kumar SP Role of SCF ubiquitin-ligase and the COP9 signalosome in the N gene-mediated resistance response to Tobacco mosaic virus	13	1
66	3	66 2002 PLANT CELL 14(8):1919-1935 Xu LH; Liu FQ; Lechner E; Genschik P; Crosby WL; Ma H; Peng W; Huang DF; Xie DX The SCFCOl1 ubiquitin-ligase complexes are required for jasmonate response in Arabidopsis	30	12
67	6	67 2002 PLANT CELL 14(9):2137-2144 Gray WM; Hellmann H; Dharmasiri S; Estelle M Role of the Arabidopsis RING-H2 protein RBX1 in RUB modification and SCF function	9	3
68	7	68 2002 PLANT CELL 14(10):2553-2563 Schwechheimer C; Serino G; Deng XW Multiple ubiquitin ligase-mediated processes require COP9 signalosome and AXR1 function	19	9
69	6	69 2002 PLANT CELL 14(12):3057-3071 del Pozo JC; Boniotti MB; Gutierrez C Arabidopsis E2Fc functions in cell division and is degraded by the ubiquitin-SCFAtSKP2 pathway in response to light	6	0
70	2	70 2002 PLANT MOLECULAR BIOLOGY 49(3-4):401-409 Dharmasiri S; Estelle M The role of regulated protein degradation in auxin response	14	3
71	1	71 2002 PLANT MOLECULAR BIOLOGY 49(3-4):411-426 Swarup R; Parry G; Graham N; Allen T; Bennett M Auxin cross-talk: integration of signalling pathways to control plant development	12	0
72	2	72 2002 PLANT MOLECULAR BIOLOGY 50(6):971-980 Ellis C; Turner JG; Devoto A Protein complexes mediate signalling in plant responses to hormones, light, sucrose and pathogens	4	2
73	1	73 2002 PLANTA 214(4):497-504 Berger S Jasmonate-related mutants of Arabidopsis as tools for studying stress signaling	13	1
74	1	74 2002 PLANTA 215(1):127-133 Molnar G; Bancos S; Nagy F; Szekeres M Characterisation of BRH1, a brassinosteroid-responsive RING-H2 gene from Arabidopsis thaliana	1	0
75	2	75 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(16):10865-10869 Peart JR; Lu R; Sadanandom A; Malcuit I; Moffett P; Brice DC; Schauser L; Jaggard DAW; Xiao SY; Coleman MJ; Dow M; Jones JDG; Shirasu K; Baulcombe DC Ubiquitin ligase-associated protein SGT1 is required for host and nonhost disease resistance in plants	31	5
76	2	76 2002 SCIENCE 295(5562):2032-2033 Nishimura M; Somerville S Plant biology - Resisting attack	1	0
77	3	77 2002 SCIENCE 295(5562):2073-2076 Azevedo C; Sadanandom A; Kitagawa K; Freialdenhoven A; Shirasu K; Schulze-Lefert P The RAR1 interactor SGT1, an essential component of R gene- triggered disease resistance	62	14
78	12	78 2002 SCIENCE 297(5582):793-797 Hellmann H; Estelle M Plant development: Regulation by protein degradation	29	10
79	4	79 2002 SCIENCE 298(5593):608-611 Cope GA; Suh GSB; Aravind L; Schwarz SE; Zipursky SL; Koonin EV; Deshaies RJ Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1	44	18
80	6	80 2002 TRENDS IN CELL BIOLOGY 12(7):308-311 Frugis G; Chua NH Ubiquitin-mediated proteolysis in plant hormone signal transduction	3	0
81	5	81 2003 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 42(4):392-411 Weiler EW Sensory principles of higher plants	0	0
82	3	82 2003 ANNUAL REVIEW OF PLANT BIOLOGY 54():23-61 Martin GB; Bogdanove AJ; Sessa G Understanding the functions of plant disease resistance proteins	2	0
83	13	83 2003 ANNUAL REVIEW OF PLANT BIOLOGY 54():165-182 Serino G; Deng XW THE COP9 signalosome: Regulating plant development through the control of proteolysis	2	1
84	4	84 2003 CELL 113(3):357-367 Groisman R; Polanowska J; Kuraoka I; Sawada J; Saijo M; Drapkin R; Kisselev AF; Tanaka K; Nakatani Y The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage	7	2
85	20	85 2003 CELL 114(6):663-671 Cope GA; Deshaies RJ COP9 signalosome: A multifunctional regulator of SCF and other cullin-based ubiquitin Ligases	0	0
86	5	86 2003 CURRENT BIOLOGY 12(13):R504-R505 Peng ZH; Shen YP; Feng SH; Wang XP; Chitteti BN; Vierstra RD; Deng XW Evidence for a physical association of the COP9 signalosome, the proteasome, and specific SCF E3 ligases in vivo	0	0
87	6	87 2003 CURRENT BIOLOGY 13(11):911-921 Pintard L; Kurz T; Glaser S; Willis JH; Peter M; Bowerman B Neddylation and deneddylation of CUL-3 is required to target MEI-1/katanin for degradation at the meiosis-to-mitosis transition in C-elegans	7	1
88	6	88 2003 DEVELOPMENT 130(5):969-981 Ma LG; Zhao HY; Deng XW Analysis of the mutational effects of the COP/DET/FUS loci on genome expression profiles reveals their overlapping yet not identical roles in regulating Arabidopsis seedling development	4	0
89	3	89 2003 DEVELOPMENTAL BIOLOGY 254(1):149-160 Tenbaum SP; Juenemann S; Schlitt T; Bernal J; Renkawitz R; Munoz A; Baniahmad A Alien/CSN2 gene expression is regulated by thyroid hormone in rat brain	0	0
90	5	90 2003 DEVELOPMENTAL BIOLOGY 260(2):289-297 Sullivan JA; Deng XW From seed to seed: the role of photoreceptors in Arabidopsis development	0	0
91	7	91 2003 DEVELOPMENTAL CELL 4(5):699-710 Doronkin S; Djagaeva I; Beckendorf SK The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis	1	1
92	8	92 2003 EMBO JOURNAL 22(6):1302-1312 Uhle S; Medalia O; Waldron R; Dumdey R; Henklein P; Bech-Otschir D; Huang X; Berse M; Sperling J; Schade R; Dubiel W Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome	1	1
93	10	93 2003 EMBO JOURNAL 22(8):1762-1770 Dharmasiri S; Dharmasiri N; Hellmann H; Estelle M The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis	2	2
94	10	94 2003 EMBO JOURNAL 22(13):3314-3325 Hellmann H; Hobbie L; Chapman A; Dharmasiri S; Dharmasiri N; del Pozo C; Reinhardt D; Estelle M Arabidopsis AXR6 encodes CUL1 implicating SCF E3 ligases in auxin regulation of embryogenesis	1	1
95	3	95 2003 FEBS LETTERS 541(1-3):102-108 Hwang JW; Min KW; Tamura T; Yoon JB TIP120A associates with unneddylated cullin 1 and regulates its neddylation	1	1
96	7	96 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(31):28882-28891 Wu K; Yamoah K; Dolios G; Gan-Erdene T; Tan PL; Chen A; Lee CG; Wei N; Wilkinson KD; Wang R; Pan ZQ DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1	2	0
97	5	97 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(44):43645-43653 Sun Y; Mochizuki Y; Majerus PW Inositol 1,3,4-trisphosphate 5/6-kinase inhibits tumor necrosis factor-induced apoptosis	0	0
98	6	98 2003 JOURNAL OF EXPERIMENTAL BOTANY 54(385):1175-1181 Koyama T; Okada T; Kitajima S; Ohme-Takagi M; Shinshi H; Sato F Isolation of tobacco ubiquitin-conjugating enzyme cDNA in a yeast two-hybrid system with tobacco ERF3 as bait and its characterization of specific interaction	0	0
99	3	99 2003 MOLECULAR AND CELLULAR BIOLOGY 23(9):3274-3286 Lagrange T; Hakimi MA; Pontier D; Courtois F; Alcaraz JP; Grunwald D; Lam E; Lerbs-Mache S Transcription factor IIB (TFIIB)-related protein (pBrp), a plant-specific member of the TFIIB-related protein family	0	0
100	10	100 2003 MOLECULAR AND CELLULAR BIOLOGY 23(19):6790-6797 Lykke-Andersen K; Schaefer L; Menon S; Deng XW; Miller JB; Wei N Disruption of the COP2 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death	0	0

Cited
nodes

LCS

1 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(4):876-882
Schmidt LS; Warren MB; Nickerson ML; Weirich G; Matrosova V; Toro JR; Turner ML; Duray P; Merino M; Hewitt S; Pavlovich CP; Glenn G; Greenberg CR; Linehan WM; Zbar B
Birt-Hogg-Dube syndrome, a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia, maps to chromosome 17p11.2

2 2001 CURRENT BIOLOGY 11(16):R643-R646
Seeger M; Gordon C; Dubiel W
Protein stability: The COP9 signalosome gets in on the act

3 2001 CURRENT OPINION IN PLANT BIOLOGY 4(5):382-386
Leyser O
Auxin signalling: the beginning, the middle and the end

4 2001 CURRENT OPINION IN PLANT BIOLOGY 4(6):478-487
Assaad FF
Of weeds and men: what genomes teach us about plant cell biology

5 2001 DEVELOPMENTAL CELL 1(5):595-604
Rogg LE; Bartel B
Auxin signaling: Derepression through regulated proteolysis

6 2001 FASEB JOURNAL 15(13):U221-U238
Lu CR; Li Y; Zhao YL; Xing GC; Tang F; Wang QM; Sun YH; Wei HD; Yang XM; Wu CS; Chen JG; Guan KL; Zhang CG; Chen HP; He FC
Intracrine hepatopoietin potentiates AP-1 activity through JAB1 independent of MAPK pathway

7 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(44):40998-41004
Wilson MP; Sun Y; Cao L; Majerus PW
Inositol 1,3,4-trisphosphate 5/6-kinase is a protein kinase that phosphorylates the transcription factors c-Jun and ATF-2

8 2001 JOURNAL OF PLANT GROWTH REGULATION 20(3):195-197
Jones AM
Keeping the momentum in auxin research

9 2001 JOURNAL OF PLANT GROWTH REGULATION 20(3):255-264
Chen JG
Dual auxin signaling pathways control cell elongation and division

10 2001 JOURNAL OF PLANT GROWTH REGULATION 20(3):265-273
Ward SP; Estelle M
Auxin signaling involves regulated protein degradation by the ubiquitin-proteasome pathway

11 2001 JOURNAL OF PLANT GROWTH REGULATION 20(3):274-280
Tian Q; Reed JW
Molecular links between light and auxin signaling pathways

12 2001 JOURNAL OF PLANT GROWTH REGULATION 20(3):281-291
Guilfoyle TJ; Hagen G
Auxin response factors

13 2001 PLANT CELL 13(9):1983-1986
Okamoto H; Qu L; Deng XW
Does EID1 aid the fine-tuning of phytochrome A signal transduction in Arabidopsis?

14 2001 PLANT CELL 13(10):2161-2163
Eckardt NA
Auxin and the power of the proteasome in plants

15 2001 PLANT CELL 13(10):2349-2360
Ramos JA; Zenser N; Leyser O; Callis J
Rapid degradation of auxin/indoleacetic acid proteins requires conserved amino acids of domain II and is proteasome dependent

16 2001 PLANT CELL 13(11):2393-2407
Peng ZH; Serino G; Deng XW
Molecular characterization of subunit 6 of the COP9 signalosome and its role in multifaceted developmental processes in Arabidopsis

17 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(20):11795-11800
Zenser N; Ellsmore A; Leasure C; Callis J
Auxin modulates the degradation rate of Aux/IAA proteins

18 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(24):14162-14167
Dill A; Jung HS; Sun TP
The DELLA motif is essential for gibberellin-induced degradation of RGA

19 2001 SCIENCE 292(5520):1379-1382
Schwechheimer C; Serino G; Callis J; Crosby WL; Lyapina S; Deshaies RJ; Gray WM; Estelle M; Deng XW
Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIR1 in mediating auxin response

119

20 2001 SCIENCE 292(5520):1382-1385
Lyapina S; Cope G; Shevchenko A; Serino G; Tsuge T; Zhou CS; Wolf DA; Wei N; Shevchenko A; Deshaies RJ
Promotion of NEDD8-CUL1 conjugate cleavage by COP9 signalosome

122

21 2001 TRENDS IN CELL BIOLOGY 11(10):420-426
Schwechheimer C; Deng XW
COP9 signalosome revisited: a novel mediator of protein degradation

22 2001 TRENDS IN PLANT SCIENCE 6(8):379-386
Kim TH; Hofmann K; von Arnim AG; Chamovitz DA
PCI complexes: pretty complex interactions in diverse signaling pathways

23 2001 TRENDS IN PLANT SCIENCE 6(9):420-425
Reed JW
Roles and activities of Aux/IAA proteins in Arabidopsis

24 2001 TRENDS IN PLANT SCIENCE 6(10):463-470
Bachmair A; Novatchkova M; Potuschak T; Eisenhaber F
Ubiquitylation in plants: a post-genomic look at a post- translational modification

25 2002 ADVANCES IN IMMUNOLOGY, VOL 80 80():1-70
Rock KL; York IA; Saric T; Goldberg AL
Protein degradation and the generation of MHC class I-presented peptides

26 2002 ANNUAL REVIEW OF PLANT BIOLOGY 53():329-355
Nagy F; Schafer E
Phytochromes control photomorphogenesis by differentially regulated, interacting signaling pathways in higher plants

27 2002 ANNUAL REVIEW OF PLANT BIOLOGY 53():377-398
Leyser O
Molecular genetics of auxin signaling

28 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 290(1):1-10
Hasselgren PO; Wray C; Mammen J
Molecular regulation of muscle cachexia: It may be more than the proteasome

29 2002 BMC CELL BIOLOGY 3():art. no.-30
Yi CL; Wang HY; Wei N; Deng XW
An initial biochemical and cell biological characterization of the mammalian homologue of a central plant developmental switch, COP1

30 2002 BMC GENETICS 3():art. no.-15
Wee S; Hetfeld B; Dubiel W; Wolf DA
Conservation of the COP9/signalosome in budding yeast

31 2002 CHINESE SCIENCE BULLETIN 47(18):1497-1501
Wang HY; Huang J; Lai Z; Xue YB
F-box proteins in flowering plants

32 2002 CURRENT BIOLOGY 12(10):R352-R354
Gray WM
Plant defence: A new weapon in the arsenal

33 2002 CURRENT BIOLOGY 12(8):667-672
Yang XM; Menon S; Lykke-Andersen K; Tsuge T; Xiao D; Wang XP; Rodriguez-Suarez RJ; Zhang H; Wei N
The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1

34 2002 CURRENT OPINION IN CELL BIOLOGY 14(2):180-188
Quail PH
Photosensory perception and signalling in plant cells: new paradigms?

35 2002 DEVELOPMENT 129(19):4399-4409
Oron E; Mannervik M; Rencus S; Harari-Steinberg O; Neuman-Silberberg S; Sega D; Chamovitz DA
COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster

36 2002 DEVELOPMENTAL BIOLOGY 251(2):333-347
Smith P; Leung-Chiu WM; Montgomery R; Orsborn A; Kuznicki K; Gressman-Coberly E; Mutapcic L; Bennett K
The GLH proteins, Caenorhabditis elegans P granule components, associate with CSN-5 and KGB-1, proteins necessary for fertility, and with ZYX-1, a predicted cytoskeletal protein

37 2002 EMBO REPORTS 3(2):171-176
Wan M; Cao XS; Wu YL; Bai ST; Wu LY; Shi XM; Wang N; Cao X
Jab1 antagonizes TGF-beta signaling by inducing Smad4 degradation

38 2002 EMBO REPORTS 3(2):177-182
Ohh M; Kim WY; Moslehi JJ; Chen YZ; Chau V; Read MA; Kaelin WG
An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells

39 2002 EMBO REPORTS 3(11):1042-1048
Schafer E; Bowler C
Phytochrome-mediated photoperception and signal transduction in higher plants

40 2002 FEBS LETTERS 527(1-3):15-21
Alves KH; Bochard V; Rety S; Jalinot P
Association of the mammalian proto-oncoprotein Int-6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome

41 2002 GENE 298(2):109-119
Lier S; Paululat A
The proteasome regulatory particle subunit Rpn6 is required for Drosophila development and interacts physically with signalosome subunit Alien/CSN2

42 2002 GENES & DEVELOPMENT 16(5):554-559
Suzuki G; Yanagawa Y; Kwok SF; Matsui M; Deng XW
Arabidopsis COP10 is a ubiquitin-conjugating enzyme variant that acts together with COP1 and the COP9 signalosome in repressing photomorphogenesis

43 2002 GENES & DEVELOPMENT 16(10):1247-1259
Holm M; Ma LG; Qu LJ; Deng XW
Two interacting bZIP proteins are direct targets of COP1- mediated control of light-dependent gene expression in Arabidopsis

44 2002 GENES & DEVELOPMENT 16(17):2207-2212
Ritchie KJ; Malakhov MP; Hetherington CJ; Zhou LM; Little MT; Malakhova OA; Sipe JC; Orkin SH; Zhang DE
Dysregulation of protein modification by ISG15 results in brain cell injury

45 2002 GENES & DEVELOPMENT 16(18):2403-2414
Ou CY; Lin YF; Chen YJ; Chien CT
Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development

46 2002 IMMUNOLOGICAL REVIEWS 186():189-207
Rossetti G; Collinge M; Bender JR; Molteni R; Pardi R
Integrin-dependent regulation of gene expression in leukocytes

47 2002 INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 220 220():185-223
Kim TH; Kim BH; von Arnim AG
Repressors of photomorphogenesis

48 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(1):516-527
Wu K; Chen A; Tan PL; Pan ZQ
The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34

49 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(3):2302-2310
Tomoda K; Kubota Y; Arata Y; Mori S; Maeda M; Tanaka T; Yoshida M; Yoneda-Kato N; Kato JY
The cytoplasmic shuttling and subsequent degradation of p27(Kip1) mediated by Jab1/CSN5 and the COP9 signalosome complex

50 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(26):23253-23259
Amir RE; Iwai K; Ciechanover A
The NEDD8 pathway is essential for SCF beta-TrCp-mediated ubiquitination and processing of the NF-kappa B precursor p105

51 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(48):45759-45764
Sun Y; Wilson MP; Majerus PW
Inositol 1,3,4-trisphosphate 5/6-kinase associates with the COP9 signalosome by binding to CSN1

52 2002 JOURNAL OF CELL SCIENCE 115(3):467-473
Bech-Otschir D; Seeger M; Dubiel W
The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis

53 2002 MOLECULAR BIOLOGY OF THE CELL 13(2):646-655
Wang XP; Kang DM; Feng SH; Serino G; Schwechheimer C; Wei N
CSN1N-terminal-dependent activity is required for arabidopsis development but not for Rub1/Nedd8 deconjugation of cullins: A structure-function study of CSN1 subunit of COP9 signalosome

54 2002 MOLECULAR BIOLOGY OF THE CELL 13(6):1916-1928
Shen WH; Parmentier Y; Hellmann H; Lechner E; Dong AW; Masson J; Granier F; Lepiniec L; Estelle M; Genschik P
Null mutation of AtCUL1 causes arrest in early embryogenesis in Arabidopsis

55 2002 MOLECULAR ENDOCRINOLOGY 16(2):315-330
Fan MY; Long XH; Bailey JA; Reed CA; Osborne E; Gize EA; Kirk EA; Bigsby RM; Nephew KP
The activating enzyme of NEDD8 inhibits steroid receptor function

56 2002 NATURE REVIEWS MOLECULAR CELL BIOLOGY 3(2):85-93
Quail PH
Phytochrome photosensory signalling networks

57 2002 NEURON 33(1):35-46
Suh GSB; Poeck B; Chouard T; Oron E; Segal D; Chamovitz DA; Zipursky SL
Drosophila JAB1/CSN5 acts in photoreceptor cells to induce glial cells

58 2002 NEW PHYTOLOGIST 154(3):553-590
Moller SG; Ingles PJ; Whitelam GC
The cell biology of phytochrome signalling

59 2002 ONCOGENE 21(22):3507-3516
Gemmill RM; Bemis LT; Lee JP; Sozen MA; Baron A; Zeng C; Erickson PF; Hooper JE; Drabkin HA
The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway

60 2002 PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY 61(2):73-76
Peart JR; Shirasu K
"To degrade or not to degrade?" - the emerging question in plant disease resistance

61 2002 PHYSIOLOGICAL REVIEWS 82(2):373-428
Glickman MH; Ciechanover A
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction

114

62 2002 PLANT CELL 14():S5-S8
Dodds PN; Schwechheimer C
A breakdown in defense signaling

63 2002 PLANT CELL 14(1):17-32
Smalle J; Kurepa J; Yang PZ; Babiychuk E; Kushnir S; Durski A; Vierstra RD
Cytokinin growth responses in Arabidopsis involve the 26S proteasome subunit RPN12

64 2002 PLANT CELL 14():S81-S95
Kepinski S; Leyser O
Ubiquitination and auxin signaling: A degrading story

65 2002 PLANT CELL 14(7):1483-1496
Liu Y; Schiff M; Serino G; Deng XW; Dinesh-Kumar SP
Role of SCF ubiquitin-ligase and the COP9 signalosome in the N gene-mediated resistance response to Tobacco mosaic virus

66 2002 PLANT CELL 14(8):1919-1935
Xu LH; Liu FQ; Lechner E; Genschik P; Crosby WL; Ma H; Peng W; Huang DF; Xie DX
The SCFCOl1 ubiquitin-ligase complexes are required for jasmonate response in Arabidopsis

67 2002 PLANT CELL 14(9):2137-2144
Gray WM; Hellmann H; Dharmasiri S; Estelle M
Role of the Arabidopsis RING-H2 protein RBX1 in RUB modification and SCF function

68 2002 PLANT CELL 14(10):2553-2563
Schwechheimer C; Serino G; Deng XW
Multiple ubiquitin ligase-mediated processes require COP9 signalosome and AXR1 function

69 2002 PLANT CELL 14(12):3057-3071
del Pozo JC; Boniotti MB; Gutierrez C
Arabidopsis E2Fc functions in cell division and is degraded by the ubiquitin-SCFAtSKP2 pathway in response to light

70 2002 PLANT MOLECULAR BIOLOGY 49(3-4):401-409
Dharmasiri S; Estelle M
The role of regulated protein degradation in auxin response

71 2002 PLANT MOLECULAR BIOLOGY 49(3-4):411-426
Swarup R; Parry G; Graham N; Allen T; Bennett M
Auxin cross-talk: integration of signalling pathways to control plant development

72 2002 PLANT MOLECULAR BIOLOGY 50(6):971-980
Ellis C; Turner JG; Devoto A
Protein complexes mediate signalling in plant responses to hormones, light, sucrose and pathogens

73 2002 PLANTA 214(4):497-504
Berger S
Jasmonate-related mutants of Arabidopsis as tools for studying stress signaling

74 2002 PLANTA 215(1):127-133
Molnar G; Bancos S; Nagy F; Szekeres M
Characterisation of BRH1, a brassinosteroid-responsive RING-H2 gene from Arabidopsis thaliana

75 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(16):10865-10869
Peart JR; Lu R; Sadanandom A; Malcuit I; Moffett P; Brice DC; Schauser L; Jaggard DAW; Xiao SY; Coleman MJ; Dow M; Jones JDG; Shirasu K; Baulcombe DC
Ubiquitin ligase-associated protein SGT1 is required for host and nonhost disease resistance in plants

76 2002 SCIENCE 295(5562):2032-2033
Nishimura M; Somerville S
Plant biology - Resisting attack

77 2002 SCIENCE 295(5562):2073-2076
Azevedo C; Sadanandom A; Kitagawa K; Freialdenhoven A; Shirasu K; Schulze-Lefert P
The RAR1 interactor SGT1, an essential component of R gene- triggered disease resistance

78 2002 SCIENCE 297(5582):793-797
Hellmann H; Estelle M
Plant development: Regulation by protein degradation

79 2002 SCIENCE 298(5593):608-611
Cope GA; Suh GSB; Aravind L; Schwarz SE; Zipursky SL; Koonin EV; Deshaies RJ
Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1

80 2002 TRENDS IN CELL BIOLOGY 12(7):308-311
Frugis G; Chua NH
Ubiquitin-mediated proteolysis in plant hormone signal transduction

81 2003 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 42(4):392-411
Weiler EW
Sensory principles of higher plants

82 2003 ANNUAL REVIEW OF PLANT BIOLOGY 54():23-61
Martin GB; Bogdanove AJ; Sessa G
Understanding the functions of plant disease resistance proteins

83 2003 ANNUAL REVIEW OF PLANT BIOLOGY 54():165-182
Serino G; Deng XW
THE COP9 signalosome: Regulating plant development through the control of proteolysis

84 2003 CELL 113(3):357-367
Groisman R; Polanowska J; Kuraoka I; Sawada J; Saijo M; Drapkin R; Kisselev AF; Tanaka K; Nakatani Y
The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

85 2003 CELL 114(6):663-671
Cope GA; Deshaies RJ
COP9 signalosome: A multifunctional regulator of SCF and other cullin-based ubiquitin Ligases

86 2003 CURRENT BIOLOGY 12(13):R504-R505
Peng ZH; Shen YP; Feng SH; Wang XP; Chitteti BN; Vierstra RD; Deng XW
Evidence for a physical association of the COP9 signalosome, the proteasome, and specific SCF E3 ligases in vivo

87 2003 CURRENT BIOLOGY 13(11):911-921
Pintard L; Kurz T; Glaser S; Willis JH; Peter M; Bowerman B
Neddylation and deneddylation of CUL-3 is required to target MEI-1/katanin for degradation at the meiosis-to-mitosis transition in C-elegans

88 2003 DEVELOPMENT 130(5):969-981
Ma LG; Zhao HY; Deng XW
Analysis of the mutational effects of the COP/DET/FUS loci on genome expression profiles reveals their overlapping yet not identical roles in regulating Arabidopsis seedling development

89 2003 DEVELOPMENTAL BIOLOGY 254(1):149-160
Tenbaum SP; Juenemann S; Schlitt T; Bernal J; Renkawitz R; Munoz A; Baniahmad A
Alien/CSN2 gene expression is regulated by thyroid hormone in rat brain

90 2003 DEVELOPMENTAL BIOLOGY 260(2):289-297
Sullivan JA; Deng XW
From seed to seed: the role of photoreceptors in Arabidopsis development

91 2003 DEVELOPMENTAL CELL 4(5):699-710
Doronkin S; Djagaeva I; Beckendorf SK
The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis

92 2003 EMBO JOURNAL 22(6):1302-1312
Uhle S; Medalia O; Waldron R; Dumdey R; Henklein P; Bech-Otschir D; Huang X; Berse M; Sperling J; Schade R; Dubiel W
Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome

93 2003 EMBO JOURNAL 22(8):1762-1770
Dharmasiri S; Dharmasiri N; Hellmann H; Estelle M
The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis

94 2003 EMBO JOURNAL 22(13):3314-3325
Hellmann H; Hobbie L; Chapman A; Dharmasiri S; Dharmasiri N; del Pozo C; Reinhardt D; Estelle M
Arabidopsis AXR6 encodes CUL1 implicating SCF E3 ligases in auxin regulation of embryogenesis

95 2003 FEBS LETTERS 541(1-3):102-108
Hwang JW; Min KW; Tamura T; Yoon JB
TIP120A associates with unneddylated cullin 1 and regulates its neddylation

96 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(31):28882-28891
Wu K; Yamoah K; Dolios G; Gan-Erdene T; Tan PL; Chen A; Lee CG; Wei N; Wilkinson KD; Wang R; Pan ZQ
DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1

97 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(44):43645-43653
Sun Y; Mochizuki Y; Majerus PW
Inositol 1,3,4-trisphosphate 5/6-kinase inhibits tumor necrosis factor-induced apoptosis

98 2003 JOURNAL OF EXPERIMENTAL BOTANY 54(385):1175-1181
Koyama T; Okada T; Kitajima S; Ohme-Takagi M; Shinshi H; Sato F
Isolation of tobacco ubiquitin-conjugating enzyme cDNA in a yeast two-hybrid system with tobacco ERF3 as bait and its characterization of specific interaction

99 2003 MOLECULAR AND CELLULAR BIOLOGY 23(9):3274-3286
Lagrange T; Hakimi MA; Pontier D; Courtois F; Alcaraz JP; Grunwald D; Lam E; Lerbs-Mache S
Transcription factor IIB (TFIIB)-related protein (pBrp), a plant-specific member of the TFIIB-related protein family

100

100 2003 MOLECULAR AND CELLULAR BIOLOGY 23(19):6790-6797
Lykke-Andersen K; Schaefer L; Menon S; Deng XW; Miller JB; Wei N
Disruption of the COP2 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death

#	Cited nodes	Nodes / Authors	GCS	LCS
101	7	101 2003 MOLECULAR CELL 11(4):927-938 Zhou CS; Wee S; Rhee E; Naumann M; Dubiel W; Wolf DA Fission yeast COP9/signalosome suppresses cullin acivity through recruitment of the deubiquitylating enzyme Ubp12p	4	2
102	6	102 2003 MOLECULAR ENDOCRINOLOGY 17(3):356-365 Fan MY; Bigsby RM; Nephew KP The NEDD8 pathway is required for proteasome-mediated degradation of human estrogen receptor (ER)-alpha and essential for the anti proliferative activity of ICI 182,780 in ER alpha- positive breast cancer cells	4	0
103	7	103 2003 MOLECULAR MICROBIOLOGY 49(3):717-730 Busch S; Eckert SE; Krappmann S; Braus GH The COP9 signalosome is an essential regulator of development in the filamentous fungus Aspergillus nidulans	0	0
104	9	104 2003 MOLECULAR PLANT PATHOLOGY 4(4):287-296 Tor M; Yemm A; Holub E The role of proteolysis in R gene mediated defence in plants	0	0
105	10	105 2003 NEW PHYTOLOGIST 157(3):449-463 Halliday KJ; Fankhauser C Phytochrome-hormonal signalling networks	0	0
106	2	106 2003 PLANT CELL 15(3):580-581 Eckardt NA Characterization of the last subunit of the Arabidopsis COP9 signalosome	0	0
107	8	107 2003 PLANT CELL 15(3):719-731 Serinoa G; Su HW; Peng ZH; Tsuge T; Weia N; Gu HY; Deng XW Characterization of the last subunit of the Arabidopsis COP9 signalosome: Implications for the overall structure and origin of the complex	4	3
108	12	108 2003 PLANT CELL 15(5):1071-1082 Wang XP; Feng SH; Nakayama N; Crosby WL; Irish V; Deng XW; Wei N The COP9 signalosome interacts with SCFUFO and participates in Arabidopsis flower development	4	3
109	9	109 2003 PLANT CELL 15(5):1083-1094 Feng SH; Ma LG; Wang XP; Xie DX; Dinesh-Kumar SP; Wei N; Deng XW The COP9 signalosome interacts physically with SCFCOI1 and modulates jasmonate responses	6	4
110	1	110 2003 PLANT JOURNAL 35(1):57-70 Kanyuka K; Praekelt U; Franklin KA; Billingham OE; Hooley R; Whitelam GC; Halliday KJ Mutations in the huge Arabidopsis gene BIG affect a range of hormone and light responses	0	0
111	7	111 2003 PLANT JOURNAL 36(5):643-651 Tian Q; Nagpal P; Reed JW Regulation of Arabidopsis SHY2/IAA3 protein turnover	0	0
112	6	112 2003 PLANT PHYSIOLOGY 131(3):1302-1312 Rober-Kleber N; Albrechtova JTP; Fleig S; Huck N; Michalke W; Wagner E; Speth V; Neuhaus G; Fischer-Iglesias C Plasma membrane H+-ATPase is involved in auxin-mediated cell elongation during wheat embryo development	0	0
113	3	113 2003 PLANT PHYSIOLOGY 133(1):203-217 Zhao DZ; Ni WM; Feng BM; Han TF; Petrasek MG; Ma H Members of the Arabidopsis-SKP1-like gene family xhibit a variety of expression patterns and may play diverse roles in Arabidopsis	0	0
114	5	114 2003 PLANT PHYSIOLOGY 133(3):1135-1147 Oono Y; Ooura C; Rahman A; Aspuria ET; Hayashi K; Tanaka A; Uchimiya H p-chlorophenoxyisobutyric acid impairs auxin response in Arabidopsis root	0	0
115	5	115 2003 TRENDS IN BIOCHEMICAL SCIENCES 28(6):321-328 Schwartz DC; Hochstrasser M A superfamily of protein tags: ubiquitin, SUMO and related modifiers	1	0
116	10	116 2003 TRENDS IN CELL BIOLOGY 13(10):507-509 Li L; Deng XW The COP9 signalosome: an alternative lid for the 26S proteasome?	0	0
117	4	117 2003 TRENDS IN GENETICS 19(7):409-413 Cheong JJ; Choi YD Methyl jasmonate as a vital substance in plants	0	0
118	14	118 2003 TRENDS IN PLANT SCIENCE 8(3):135-142 Vierstra RD The ubiquitin/26S proteasome pathway, the complex last chapter in the life of many plant proteins	8	0
119	4	119 2003 TRENDS IN PLANT SCIENCE 8(4):172-178 Wang HY; Deng XW Dissecting the phytochrome A-dependent signaling network in higher plants	1	0
120	6	120 2003 TRENDS IN PLANT SCIENCE 8(6):252-258 Shirasu K; Schulze-Lefert P Complex formation, promiscuity and multi-functionality: protein interactions in disease-resistance pathways	2	0

Cited
nodes

Nodes / Authors

GCS

LCS

101

101 2003 MOLECULAR CELL 11(4):927-938
Zhou CS; Wee S; Rhee E; Naumann M; Dubiel W; Wolf DA
Fission yeast COP9/signalosome suppresses cullin acivity through recruitment of the deubiquitylating enzyme Ubp12p

102

102 2003 MOLECULAR ENDOCRINOLOGY 17(3):356-365
Fan MY; Bigsby RM; Nephew KP
The NEDD8 pathway is required for proteasome-mediated degradation of human estrogen receptor (ER)-alpha and essential for the anti proliferative activity of ICI 182,780 in ER alpha- positive breast cancer cells

103

103 2003 MOLECULAR MICROBIOLOGY 49(3):717-730
Busch S; Eckert SE; Krappmann S; Braus GH
The COP9 signalosome is an essential regulator of development in the filamentous fungus Aspergillus nidulans

104

104 2003 MOLECULAR PLANT PATHOLOGY 4(4):287-296
Tor M; Yemm A; Holub E
The role of proteolysis in R gene mediated defence in plants

105

105 2003 NEW PHYTOLOGIST 157(3):449-463
Halliday KJ; Fankhauser C
Phytochrome-hormonal signalling networks

106

106 2003 PLANT CELL 15(3):580-581
Eckardt NA
Characterization of the last subunit of the Arabidopsis COP9 signalosome

107

107 2003 PLANT CELL 15(3):719-731
Serinoa G; Su HW; Peng ZH; Tsuge T; Weia N; Gu HY; Deng XW
Characterization of the last subunit of the Arabidopsis COP9 signalosome: Implications for the overall structure and origin of the complex

108

108 2003 PLANT CELL 15(5):1071-1082
Wang XP; Feng SH; Nakayama N; Crosby WL; Irish V; Deng XW; Wei N
The COP9 signalosome interacts with SCFUFO and participates in Arabidopsis flower development

109

109 2003 PLANT CELL 15(5):1083-1094
Feng SH; Ma LG; Wang XP; Xie DX; Dinesh-Kumar SP; Wei N; Deng XW
The COP9 signalosome interacts physically with SCFCOI1 and modulates jasmonate responses

110

110 2003 PLANT JOURNAL 35(1):57-70
Kanyuka K; Praekelt U; Franklin KA; Billingham OE; Hooley R; Whitelam GC; Halliday KJ
Mutations in the huge Arabidopsis gene BIG affect a range of hormone and light responses

111

111 2003 PLANT JOURNAL 36(5):643-651
Tian Q; Nagpal P; Reed JW
Regulation of Arabidopsis SHY2/IAA3 protein turnover

112

112 2003 PLANT PHYSIOLOGY 131(3):1302-1312
Rober-Kleber N; Albrechtova JTP; Fleig S; Huck N; Michalke W; Wagner E; Speth V; Neuhaus G; Fischer-Iglesias C
Plasma membrane H+-ATPase is involved in auxin-mediated cell elongation during wheat embryo development

113

113 2003 PLANT PHYSIOLOGY 133(1):203-217
Zhao DZ; Ni WM; Feng BM; Han TF; Petrasek MG; Ma H
Members of the Arabidopsis-SKP1-like gene family xhibit a variety of expression patterns and may play diverse roles in Arabidopsis

114

114 2003 PLANT PHYSIOLOGY 133(3):1135-1147
Oono Y; Ooura C; Rahman A; Aspuria ET; Hayashi K; Tanaka A; Uchimiya H
p-chlorophenoxyisobutyric acid impairs auxin response in Arabidopsis root

115

115 2003 TRENDS IN BIOCHEMICAL SCIENCES 28(6):321-328
Schwartz DC; Hochstrasser M
A superfamily of protein tags: ubiquitin, SUMO and related modifiers

116

116 2003 TRENDS IN CELL BIOLOGY 13(10):507-509
Li L; Deng XW
The COP9 signalosome: an alternative lid for the 26S proteasome?

117

117 2003 TRENDS IN GENETICS 19(7):409-413
Cheong JJ; Choi YD
Methyl jasmonate as a vital substance in plants

118

118 2003 TRENDS IN PLANT SCIENCE 8(3):135-142
Vierstra RD
The ubiquitin/26S proteasome pathway, the complex last chapter in the life of many plant proteins

119

119 2003 TRENDS IN PLANT SCIENCE 8(4):172-178
Wang HY; Deng XW
Dissecting the phytochrome A-dependent signaling network in higher plants

120

120 2003 TRENDS IN PLANT SCIENCE 8(6):252-258
Shirasu K; Schulze-Lefert P
Complex formation, promiscuity and multi-functionality: protein interactions in disease-resistance pathways