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Nodes: 158,
Authors: 657,
Journals: 82,
Outer References: 7071,
Words: 655
Collection span: 2002 - 2005
View: Overview. Sorted by date.
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 1 | 0 | 54 | 1 2002 AUG 23 CELL 110(4):521-529 Schroder ARW; Shinn P; Chen HM; Berry C; Ecker JR; et al. HIV-1 integration in the human genome favors active genes and local hotspots | 157 | 157 |
| 2 | 1 | 7 | 4 2002 NOV 14 NATURE 420(6912):116-118 Check E Gene therapy: A tragic setback | 10 | 44 |
| 3 | 1 | 18 | 3 2002 NOV [15] MOLECULAR THERAPY 6(5):570-571 Bushman F Targeting retroviral integration? | 9 | 10 |
| 4 | 1 | 9 | 2 2002 DEC [15] GENE THERAPY 9(23):1561-1562 Lemoine NR Risks and benefits of gene therapy for immunodeficiency: a reality check | 0 | 6 |
| 5 | 1 | 56 | 33 2003 JAN 3 JOURNAL OF BIOLOGICAL CHEMISTRY 278(1):372-381 Cherepanov P; Maertens G; Proost P; Devreese B; Van Beeumen J; et al. HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells | 14 | 30 |
| 6 | 1 | 29 | 12 2003 FEB 15 BLOOD 101(4):1284-1289 Woods NB; Muessig A; Schmidt M; Flygare J; Olsson K; et al. Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis | 13 | 27 |
| 7 | 1 | 132 | 47 2003 FEB [15] NATURE REVIEWS IMMUNOLOGY 3(2):97-107 Peterlin BM; Trono D Hide, shield and strike back: How HIV-infected cells avoid immune eradication | 2 | 15 |
| 8 | 3 | 207 | 13 2003 MAR 15 BLOOD 101(6):2099-2114 Baum C; Dullmann J; Li ZX; Fehse B; Meyer J; et al. Side effects of retroviral gene transfer into hematopoietic stem cells | 21 | 71 |
| 9 | 1 | 58 | 14 2003 MAR 15 BLOOD 101(6):2191-2198 Laufs S; Gentner B; Nagy KZ; Jauch A; Benner A; et al. Retroviral vector integration occurs in preferred genomic targets of human bone marrow-repopulating cells | 12 | 20 |
| 10 | 1 | 19 | 9 2003 MAR 24 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 13(6):1175-1177 Zhao L; O'Reilly MK; Shultz MD; Chmielewski J Interfacial peptide inhibitors of HIV-1 integrase activity and dimerization | 1 | 6 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 11 | 3 | 192 | 8 2003 APR 7 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1640(1):1-24 Brenner S; Malech HL Current developments in the design of onco-retrovirus and lentivirus vector systems for hematopoietic cell gene therapy | 3 | 11 |
| 12 | 1 | 57 | 15 2003 APR 15 BLOOD 101(8):2932-2939 Rivella S; May C; Chadburn A; Riviere I; Sadelain M A novel murine model of Cooley anemia and its rescue by lentiviral-mediated human beta-globin gene transfer | 6 | 16 |
| 13 | 1 | 33 | 26 2003 APR 15 EMBO JOURNAL 22(8):1868-1877 Jordan A; Bisgrove D; Verdin E HIV reproducibly establishes a latent infection after acute infection of T cells in vitro | 9 | 19 |
| 14 | 3 | 49 | 53 2003 MAY 13 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(10):5586-5588 Sandmeyer S Integration by design | 8 | 13 |
| 15 | 1 | 36 | 54 2003 MAY 13 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(10):5891-5895 Zhu YX; Dai JB; Fuerst PG; Voytas DF Controlling integration specificity of a yeast retrotransposon | 9 | 15 |
| 16 | 1 | 20 | 42 2003 MAY [15] NATURE BIOTECHNOLOGY 21(5):569-572 Ikeda Y; Takeuchi Y; Martin F; Cosset FL; Mitrophanous K; et al. Continuous high-titer HIV-1 vector production | 0 | 8 |
| 17 | 3 | 120 | 46 2003 MAY [15] NATURE REVIEWS GENETICS 4(5):346-358 Thomas CE; Ehrhardt A; Kay MA Progress and problems with the use of viral vectors for gene therapy | 9 | 81 |
| 18 | 1 | 176 | 48 2003 MAY [15] NATURE REVIEWS NEUROSCIENCE 4(5):353-364 Davidson BL; Breakefield XO Viral vectors for gene delivery to the nervous system | 0 | 19 |
| 19 | 1 | 3 | 41 2003 JUN 5 NATURE 423(6940):573-574 Check E Harmful potential of viral vectors fuels doubts over gene therapy | 0 | 4 |
| 20 | 2 | 15 | 56 2003 JUN 13 SCIENCE 300(5626):1670-1671 Trono D Picking the right spot | 1 | 2 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 21 | 2 | 18 | 57 2003 JUN 13 SCIENCE 300(5626):1749-1751 Wu XL; Li Y; Crise B; Burgess SM Transcription start regions in the human genome are favored targets for MLV integration | 66 | 98 |
| 22 | 2 | 61 | 16 2003 JUN 15 BLOOD 101(12):4717-4724 Ramezani A; Hawley TS; Hawley RG Performance-and safety-enhanced lentiviral vectors containing the human interferon-beta scaffold attachment region and the chicken beta-globin insulator | 7 | 19 |
| 23 | 1 | 47 | 49 2003 JUN 15 NUCLEIC ACIDS RESEARCH 31(12):3248-3256 Rampalli S; Kulkarni A; Kumar P; Mogare D; Galande S; et al. Stimulation of Tat-independent transcriptional processivity from the HIV-1 LTR promoter by matrix attachment regions | 2 | 6 |
| 24 | 1 | 40 | 51 2003 JUN 19 ONCOGENE 22(25):3911-3916 Peterlini-Brechot P; Saigo K; Murakami Y; Chami M; Gozuacik D; et al. Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene | 0 | 0 |
| 25 | 1 | 64 | 11 2003 [JUN 30] BIOTECHNOLOGY & GENETIC ENGINEERING REVIEWS, VOL 20 20:77-100 Gentile A; D'Alessandro L; Medico E Gene trapping: a multi-purpose tool for functional genomics | 0 | 0 |
| 26 | 1 | 150 | 19 2003 [JUN 30] CELLULAR FACTORS INVOLVED IN EARLY STEPS OF RETROVIRAL REPLICATON 281:179-208 Dvorin JD; Malim MH Intracellular trafficking of HIV-1 cores: Journey to the center of the cell | 3 | 5 |
| 27 | 1 | 35 | 31 2003 [JUN 30] HEMATOPOIETIC STEM CELLS 2002: GENETICS AND FUNCTION 996:101-111 Nienhuis AW; Hanawa H; Sawai N; Sorrentino BP; Persons DA Development of gene therapy for hemoglobin disorders | 0 | 1 |
| 28 | 1 | 20 | 32 2003 JUL 1 JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES 33(3):308-320 Mack KD; Jin X; Yu S; Wei R; Kapp L; et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression | 4 | 6 |
| 29 | 2 | 288 | 20 2003 JUL [15] CURRENT HIV RESEARCH 1(3):343-362 Pumfery A; Deng LW; Maddukuri A; de la Fuente C; Li H; et al. Chromatin remodeling and modification during HIV-1 tat-activated transcription | 1 | 6 |
| 30 | 1 | 33 | 28 2003 JUL [15] GENOME RESEARCH 13(7):1765-1774 Khambata-Ford S; Liu YY; Gleason C; Dickson M; Altman RB; et al. Identification of promoter regions in the human genome by using a retroviral plasmid library-based functional reporter gene assay | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 31 | 1 | 29 | 43 2003 JUL [15] NATURE GENETICS 34(3):297-302 Nakai H; Montini E; Fuess S; Storm TA; Grompe M; et al. AAV serotype 2 vectors preferentially integrate into active genes in mice | 16 | 55 |
| 32 | 1 | 120 | 44 2003 JUL [15] NATURE MEDICINE 9(7):853-860 Stevenson M HIV-1 pathogenesis | 2 | 24 |
| 33 | 2 | 98 | 45 2003 JUL [15] NATURE REVIEWS CANCER 3(7):477-488 Kohn DB; Sadelain M; Glorioso JC Occurrence of leukaemia following gene therapy of X-linked SCID | 6 | 44 |
| 34 | 1 | 25 | 58 2003 AUG 1 SCIENCE 301(5633):653-657 Alonso JM; Stepanova AN; Leisse TJ; Kim CJ; Chen HM; et al. Genome-wide Insertional mutagenesis of Arabidopsis thaliana | 1 | 201 |
| 35 | 6 | 52 | 22 2003 AUG [15] CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(4):376-382 Portlock JL; Calos MP Site-specific genomic strategies for gene therapy | 1 | 1 |
| 36 | 1 | 62 | 35 2003 AUG [15] JOURNAL OF VIROLOGY 77(15):8227-8236 Lin X; Irwin D; Kanazawa S; Huang L; Romeo J; et al. Transcriptional profiles of latent human immunodeficiency virus in infected individuals: Effects of tat on the host and reservoir | 2 | 9 |
| 37 | 1 | 73 | 38 2003 AUG [15] MOLECULAR THERAPY 8(2):196-206 Li MJ; Bauer G; Michienzi A; Yee JK; Lee NS; et al. Inhibition of HIV-1 infection by lentiviral vectors expressing pol III-promoted anti-HIV RNAs | 1 | 16 |
| 38 | 2 | 25 | 40 2003 AUG [15] MONATSSCHRIFT KINDERHEILKUNDE 151(8):869-874 Urschel S; Schmidt S; Hoffmann F; Chedville G; Fischer A; et al. Somatic gene therapy for X-chromosomal recessive severe combined immunodeficiency (X-SCID) | 0 | 0 |
| 39 | 1 | 37 | 52 2003 AUG [15] PLANT CELL 15(8):1771-1780 Miyao A; Tanaka K; Murata K; Sawaki H; Takeda S; et al. Target site specificity of the Tos17 retrotransposon shows a preference for insertion within genes and against insertion in retrotransposon-rich regions of the genome | 0 | 17 |
| 40 | 3 | 69 | 34 2003 AUG 29 JOURNAL OF BIOLOGICAL CHEMISTRY 278(35):33528-33539 Maertens G; Cherepanov P; Pluymers W; Busschots K; De Clercq E; et al. LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells | 9 | 21 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 41 | 1 | 53 | 29 2003 SEP [15] GENOME RESEARCH 13(9):1984-1997 Bowen NJ; Jordan IK; Epstein JA; Wood V; Levin HL Retrotransposons and their recognition of pol II promoters: A comprehensive survey of the transposable elements from the complete genome sequence of Schizosaccharomyces pombe | 1 | 6 |
| 42 | 1 | 15 | 30 2003 SEP [15] GENOME RESEARCH 13(9):1998-2004 Versteeg R; van Schaik BDC; van Batenburg MF; Roos M; Monajemi R; et al. The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern for domains of highly and weakly expressed genes | 4 | 29 |
| 43 | 3 | 65 | 17 2003 OCT 1 BLOOD 102(7):2403-2411 Ehrhardt A; Xu H; Dillow AM; Bellinger DA; Nichols TC; et al. A gene-deleted adenoviral vector results in phenotypic correction of canine hemophilia B without liver toxicity or thrombocytopenia | 0 | 6 |
| 44 | 5 | 246 | 21 2003 OCT [15] CURRENT HIV RESEARCH 1(4):419-439 Cockrell AS; Kafri T HIV-1 vectors: Fulfillment of expectations, further advancements, and still a way to go | 0 | 1 |
| 45 | 8 | 37 | 23 2003 OCT [15] CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(5):458-462 Baum C; Fehse B Mutagenesis by retroviral transgene insertion: Risk assessment and potential alternatives | 1 | 2 |
| 46 | 6 | 96 | 24 2003 OCT [15] CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(5):508-516 Persons DA Update on gene therapy for hemoglobin disorders | 2 | 3 |
| 47 | 2 | 144 | 25 2003 OCT [15] CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(5):529-540 Poeschla EM Non-primate lentiviral vectors | 1 | 4 |
| 48 | 1 | 35 | 39 2003 OCT [15] MOLECULAR THERAPY 8(4):674-687 Mitchell R; Chiang CY; Berry C; Bushman F Global analysis of cellular transcription following infection with an HIV-based vector | 1 | 5 |
| 49 | 7 | 18 | 18 2003 OCT 17 CELL 115(2):135-138 Bushman FD Targeting survival: Integration site selection by retroviruses and LTR-retrotransposons | 12 | 20 |
| 50 | 4 | 9 | 59 2003 OCT 17 SCIENCE 302(5644):400-401 Williams DA; Baum C Gene therapy - New challenges ahead | 3 | 16 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 51 | 2 | 38 | 60 2003 OCT 17 SCIENCE 302(5644):415-419 Hacein-Bey-Abina S; Von Kalle C; Schmidt M; McCcormack MP; Wulffraat N; et al. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1 | 36 | 174 |
| 52 | 1 | 33 | 50 2003 NOV 1 NUCLEIC ACIDS RESEARCH 31(21):6180-6190 Tsai CL; Chatterji M; Schatz DG DNA mismatches and GC-rich motifs target transposition by the RAG1/RAG2 transposase | 0 | 6 |
| 53 | 4 | 99 | 5 2003 NOV-DEC [NOV 15] ARCHIVES OF MEDICAL RESEARCH 34(6):589-599 Bueren JA; Guenechea G; Casado JA; Lamana ML; Segovia JC Genetic modification of hematopoietic stem cells: recent advances in the gene therapy of inherited diseases | 0 | 0 |
| 54 | 2 | 19 | 10 2003 NOV [15] BIOTECHNIQUES 35(5):1072-+ Yao AQ; Chiu R; Vora A; Brown DB; Grandgenett D; et al. Avian retrovirus integrase-enhanced transgene integration into mammalian cell DNA in vivo | 0 | 1 |
| 55 | 3 | 32 | 27 2003 NOV [15] GENE THERAPY 10(24):1999-2004 Gaspar HB; Howe S; Thrasher AJ Gene therapy progress and prospects: gene therapy for severe combined immunodeficiency | 1 | 5 |
| 56 | 2 | 3 | 55 2003 NOV [15] QJM-AN INTERNATIONAL JOURNAL OF MEDICINE 96(11):873-874 Berry C Misplaced | 0 | 0 |
| 57 | 1 | 37 | 7 2003 NOV 21 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 311(3):641-648 Hejnar J; Elleder D; Hajkova P; Walter J; Blazkova J; et al. Demethylation of host-cell DNA at the site of avian retrovirus integration | 0 | 0 |
| 58 | 1 | 34 | 6 2003 DEC [15] ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 23(12):2266-2272 Herder C; Tonn T; Oostendorp R; Becker S; Keller U; et al. Sustained expansion and transgene expression of coagulation factor VIII-transduced cord blood-derived endothelial progenitor cells | 0 | 3 |
| 59 | 3 | 86 | 36 2003 DEC [15] JOURNAL OF VIROLOGY 77(23):12507-12522 Violot S; Hong SS; Rakotobe D; Petit C; Gay B; et al. The human Polycomb group EED protein interacts with the integrase of human immunodeficiency virus type 1 | 5 | 6 |
| 60 | 2 | 67 | 37 2003 DEC [15] JOURNAL OF VIROLOGY 77(24):13084-13092 Mansharamani M; Graham DRM; Monie D; Lee KK; Hildreth JEK; et al. Barrier-to-autointegration factor BAF binds p55 Gag and matrix and is a host component of human immunodeficiency virus type 1 virions | 3 | 6 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 61 | 7 | 64 | 61 2004 JAN-MAR [JAN 15] AIDS REVIEWS 6(1):13-21 Cereseto A; Giacca M Integration site selection by retroviruses | 0 | 0 |
| 62 | 4 | 97 | 83 2004 JAN [15] CURRENT GENOMICS 5(1):19-35 Buchschacher GL Safety considerations associated with development and clinical application of lentiviral vector systems for gene transfer | 0 | 0 |
| 63 | 2 | 36 | 95 2004 JAN [15] FRONTIERS IN BIOSCIENCE 9:255-261 Shiramizu B; Gartner S; Cho M; Liu YL; Pyron N; et al. Assessment of HIV-1 DNA copies per cell by real-time polymerase chain reaction | 0 | 1 |
| 64 | 5 | 54 | 125 2004 JAN [15] MOLECULAR THERAPY 9(1):5-13 Baum C; von Kalle C; Staal FJT; Li ZX; Fehse B; et al. Chance or necessity? Insertional mutagenesis in gene therapy and its consequences | 4 | 9 |
| 65 | 2 | 67 | 144 2004 JAN [15] WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE 16(1):23-33 Chandler LA; Sosnowski BA Gene therapy for cutaneous wound repair | 0 | 2 |
| 66 | 1 | 101 | 97 2004 FEB 4 GENE 326:1-11 Marcello A; Lusic M; Pegoraro G; Pellegrini V; Beltram F; et al. Nuclear organization and the control of HIV-1 transcription | 0 | 2 |
| 67 | 4 | 58 | 124 2004 FEB 13 MOLECULAR CELL 13(3):403-414 Hickman AB; Ronning DR; Perez ZN; Kotin RM; Dyda F The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces | 0 | 4 |
| 68 | 1 | 165 | 71 2004 FEB [15] BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY 39:3-16 Kelm JM; Kramer BP; Gonzalez-Nicolini V; Ley B; Fussenegger M Synergies of microtissue design, viral transduction and adjustable transgene expression for regenerative medicine | 0 | 2 |
| 69 | 4 | 165 | 109 2004 FEB [15] JOURNAL OF GENE MEDICINE 6:S67-S82 Pages JC; Bru T Toolbox for retrovectorologists | 0 | 2 |
| 70 | 1 | 158 | 110 2004 FEB [15] JOURNAL OF GENE MEDICINE 6:S95-S104 Saenz DT; Poeschla EM FIV: from lentivirus to lentivector | 0 | 4 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 71 | 1 | 57 | 116 2004 FEB [15] JOURNAL OF VIROLOGY 78(3):1301-1313 Tan WJ; Zhu K; Segal DJ; Barbas CF; Chow SA Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein E2C direct integration of viral DNA into specific sites | 3 | 5 |
| 72 | 7 | 81 | 126 2004 FEB [15] MOLECULAR THERAPY 9(2):147-156 Izsvak Z; Ivics Z Sleeping Beauty transposition: Biology and applications for molecular therapy | 2 | 12 |
| 73 | 5 | 84 | 137 2004 MAR 12 SCIENCE 303(5664):1626-1632 Kazazian HH Mobile elements: Drivers of genome evolution | 0 | 36 |
| 74 | 2 | 22 | 77 2004 MAR [15] CELLULAR AND MOLECULAR LIFE SCIENCES 61(6):721-726 Tsyba L; Rynditch AV; Boeri E; Jabbari K; Bernardi G Distribution of HIV-1 in the genomes of AIDS patients | 0 | 0 |
| 75 | 2 | 113 | 80 2004 MAR [15] CURRENT GENE THERAPY 4(1):65-77 Fuller M; Anson DS Can the use of HIV-1 derived gene transfer vectors for clinical application be justified? | 0 | 0 |
| 76 | 2 | 45 | 111 2004 MAR [15] JOURNAL OF GENE MEDICINE 6(3):268-277 van Griensven J; Zhan XJ; Van Maele B; Pluymers W; Michiels M; et al. Expression of HIV-1 integrase in CEM cells inhibits HIV-1 replication | 0 | 0 |
| 77 | 1 | 46 | 112 2004 MAR [15] JOURNAL OF HUMAN GENETICS 49(3):154-165 Ozawa T; Itoyama T; Sadamori N; Yamada Y; Hata T; et al. Rapid isolation of viral integration site reveals frequent integration of HTLV-1 into expressed loci | 0 | 0 |
| 78 | 2 | 24 | 106 2004 APR 8 JOURNAL OF BIOTECHNOLOGY 109(1-2):193-199 Sandberg LM; Bjurling A; Busson P; Vasi J; Lemmens R Thiophilic interaction chromatography for supercoiled plasmid DNA purification | 0 | 3 |
| 79 | 4 | 183 | 84 2004 APR [15] CURRENT HIV RESEARCH 2(2):99-111 Hamer DH Can HIV be cured? Mechanisms of HIV persistence and strategies to combat it | 0 | 1 |
| 80 | 2 | 55 | 100 2004 APR [15] HUMAN GENE THERAPY 15(4):361-372 Vargas J; Gusella GL; Najfeld V; Klotman ME; Cara A Novel integrase-defective lentiviral episomal vectors for gene transfer | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 81 | 6 | 85 | 103 2004 APR [15] JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 113(4):595-603 Chinen J; Puck JM Successes and risks of gene therapy in primary immunodeficiencies | 0 | 5 |
| 82 | 2 | 18 | 132 2004 APR 30 MOLECULES AND CELLS 17(2):297-303 Park SW; Choi SY A stable gene transfer system for hematopoietic progenitor cells from human bone marrow using pseudotyped retroviral vectors | 0 | 0 |
| 83 | 2 | 50 | 101 2004 MAY [15] HUMAN GENE THERAPY 15(5):445-456 Bao LL; Jaligam V; Zhang XY; Kutner RH; Kantrow SP; et al. Stable transgene expression in tumors and metastases after transduction with lentiviral vectors based on human immunodeficiency virus type 1 | 0 | 1 |
| 84 | 1 | 36 | 133 2004 MAY [15] NATURE STRUCTURAL & MOLECULAR BIOLOGY 11(5):435-442 Yu Q; Konig R; Pillai S; Chiles K; Kearney M; et al. Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome | 0 | 28 |
| 85 | 2 | 58 | 140 2004 MAY [15] TRENDS IN CELL BIOLOGY 14(5):261-266 Segura-Totten M; Wilson KL BAF: roles in chromatin, nuclear structure and retrovirus integration | 0 | 6 |
| 86 | 8 | 80 | 72 2004 JUN 1 BLOOD 103(11):4062-4069 Hanawa H; Hematti P; Keyvanfar K; Metzger ME; Krouse A; et al. Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus-based lentiviral vector system | 4 | 6 |
| 87 | 1 | 45 | 90 2004 JUN [15] EUROPEAN JOURNAL OF IMMUNOLOGY 34(6):1705-1714 Oswald-Richter K; Grill SM; Leelawong M; Unutmaz D HIV infection of primary human T cells is determined by tunable thresholds of T cell activation | 1 | 2 |
| 88 | 4 | 43 | 117 2004 JUN [15] JOURNAL OF VIROLOGY 78(11):5848-5855 Taganov KD; Cuesta I; Daniel R; Cirillo LA; Katz RA; et al. Integrase-specific enhancement and suppression of retroviral DNA integration by compacted chromatin structure in vitro | 2 | 3 |
| 89 | 3 | 71 | 118 2004 JUN [15] JOURNAL OF VIROLOGY 78(12):6122-6133 Han YF; Lassen K; Monie D; Sedaghat AR; Shimoji S; et al. Resting CD4(+) T cells from human immunodeficiency virus type I (HIV-1)-infected individuals carry integrated HIV-1 Genomes within actively transcribed host genes | 3 | 4 |
| 90 | 3 | 27 | 127 2004 JUN [15] MOLECULAR THERAPY 9(6):923-931 Zielske SP; Lingas KT; Li Y; Gerson SL Limited lentiviral transgene expression with increasing copy number in an MGMT selection model: Lack of copy number selection by drug treatment | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 91 | 4 | 141 | 63 2004 [JUN 30] ANNUAL REVIEW OF GENETICS 38:61-85 Goff SP Genetic control of retrovirus susceptibility in mammalian cells | 0 | 1 |
| 92 | 3 | 110 | 64 2004 [JUN 30] ANNUAL REVIEW OF GENETICS 38:819-845 McCarty DM; Young SM; Samulski RJ Integration of adeno-associated virus (AAV) and recombinant AAV vectors | 0 | 1 |
| 93 | 2 | 59 | 76 2004 [JUN 30] CELLULAR AND MOLECULAR BIOLOGY 50:581-589 Kellebrew DA; Troelstrup D; Shiramizu B Preferential HIV-1 integration sites in macrophages and HIV-associated malignancies | 0 | 0 |
| 94 | 2 | 75 | 89 2004 [JUN 30] CURRENT TOPICS IN MEDICINAL CHEMISTRY 4(9):979-990 Anthony NJ HIV-1 integrase: A target for new AIDS chemotherapeutics | 0 | 1 |
| 95 | 2 | 45 | 94 2004 [JUN 30] FOLIA BIOLOGICA 50(3-4):107-119 Hughes SH The RCAS vector system | 0 | 0 |
| 96 | 2 | 172 | 134 2004 [JUN 30] NGF AND RELATED MOLECULES IN HEALTH AND DISEASE 146:451-476 Hendriks WTJ; Ruitenberg MJ; Blits B; Boer GJ; Verhaagen J Viral vector-mediated gene transfer of neurotrophins to promote regeneration of the injured spinal cord | 0 | 5 |
| 97 | 1 | 33 | 68 2004 JUL 2 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 319(3):879-887 Unsinger J; Lindenmaier W; May T; Hauser H; Wirth D Stable and strictly controlled expression of LTR-flanked autoregulated expression cassettes upon adenoviral transfer | 0 | 2 |
| 98 | 2 | 63 | 85 2004 JUL [15] CURRENT HIV RESEARCH 2(3):215-221 Killebrew D; Shiramizu B Pathogenesis of HIV-associated non-Hodgkin lymphoma | 0 | 0 |
| 99 | 4 | 243 | 91 2004 JUL [15] EXPERT OPINION ON BIOLOGICAL THERAPY 4(7):1073-1091 Prieto J; Qian C; Hernandez-Alcoceba R; Gonzalez-Aseguinolaza G; Mazzolini G; et al. Gene therapy of liver diseases | 0 | 0 |
| 100 | 3 | 179 | 123 2004 JUL [15] MEDICAL SCIENCE MONITOR 10(7):RA155-RA165 Yang QE Eradication of HIV in infected patients: Some potential approaches | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 101 | 4 | 38 | 128 2004 JUL [15] MOLECULAR THERAPY 10(1):27-36 Yao SY; Sukonnik T; Kean T; Bharadwaj RR; Pasceri P; et al. Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications | 0 | 0 |
| 102 | 3 | 33 | 69 2004 JUL 30 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 320(3):998-1006 Condiotti R; Curran MA; Nolan GP; Giladi H; Ketzinel-Gilad M; et al. Prolonged liver-specific transgene expression by a non-primate lentiviral vector | 0 | 0 |
| 103 | 2 | 82 | 142 2004 AUG 1 VIROLOGY 325(2):328-339 Albright AV; Vos RM; Gonzalez-Scarano F Low-level HIV replication in mixed glial cultures is associated with alterations in the processing of p55(Gag) | 0 | 1 |
| 104 | 4 | 94 | 79 2004 AUG [15] CURRENT DRUG METABOLISM 5(4):291-304 Witvrouw M; Van Maele B; Vercammen J; Hantson A; Engelborghs Y; et al. Novel inhibitors of HIV-1 integration | 1 | 1 |
| 105 | 1 | 61 | 86 2004 AUG [15] CURRENT OPINION IN MICROBIOLOGY 7(4):400-406 Delelis O; Lehmann-Che J; Saib A Foamy viruses - a world apart | 0 | 0 |
| 106 | 2 | 37 | 87 2004 AUG [15] CURRENT OPINION IN MICROBIOLOGY 7(4):407-411 Trkola A HIV-host interactions: vital to the virus and key to its inhibition | 0 | 0 |
| 107 | 2 | 38 | 114 2004 AUG [15] JOURNAL OF MOLECULAR EVOLUTION 59(2):227-238 Zhang R; Zhang CT Isochore structures in the genome of the plant Arabidopsis thaliana | 0 | 0 |
| 108 | 1 | 61 | 119 2004 AUG [15] JOURNAL OF VIROLOGY 78(16):8421-8436 Logan AC; Haas DL; Kafri T; Kohn DB Integrated self-inactivating lentiviral vectors produce full-length genomic transcripts competent for encapsidation and integration | 0 | 1 |
| 109 | 9 | 39 | 135 2004 AUG [15] PLOS BIOLOGY 2(8):1127-1137 Mitchell RS; Beitzel BF; Schroder ARW; Shinn P; Chen HM; et al. Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences | 0 | 0 |
| 110 | 8 | 216 | 96 2004 SEP 1 FRONTIERS IN BIOSCIENCE 9:3187-3208 Turlure F; Devroe E; Silver PA; Engelman A Human cell proteins and human immunodeficiency virus DNA integration | 3 | 4 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 111 | 2 | 54 | 75 2004 SEP 3 CELL 118(5):555-566 Gilbert N; Boyle S; Fiegler H; Woodfine K; Carter NP; et al. Chromatin architecture of the human genome: Gene-rich domains are enriched in open chromatin fibers | 1 | 7 |
| 112 | 2 | 111 | 65 2004 SEP-OCT [SEP 15] ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS 52(5):297-306 Pomerantz RJ Ludwik Hirszfeld Memorial Lecture: HIV-1 reservoirs: major molecular obstacles to viral eradication | 0 | 0 |
| 113 | 12 | 49 | 66 2004 SEP [15] BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY 17(3):493-503 Li ZX; Modlich U; Baum C Safety and efficacy in retrovirally modified haematopoietic cell therapy | 0 | 0 |
| 114 | 7 | 128 | 81 2004 SEP [15] CURRENT GENE THERAPY 4(3):263-276 Haviernik P; Bunting KD Safety concerns related to hematopoietic stem cell gene transfer using retroviral vectors | 0 | 0 |
| 115 | 6 | 126 | 92 2004 SEP [15] EXPERT OPINION ON BIOLOGICAL THERAPY 4(9):1423-1434 Barese CN; Goebel WS; Dinauer MC Gene therapy for chronic granulomatous disease | 0 | 0 |
| 116 | 1 | 49 | 102 2004 SEP [15] INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 36(9):1767-1775 Liou LY; Herrmann CH; Rice AR HIV-1 infection and regulation of Tat function in macrophages | 0 | 0 |
| 117 | 4 | 79 | 120 2004 SEP [15] JOURNAL OF VIROLOGY 78(17):9524-9537 Llano M; Vanegas M; Fregoso O; Saenz D; Chung S; et al. LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes | 4 | 4 |
| 118 | 7 | 195 | 129 2004 SEP [15] MOLECULAR THERAPY 10(3):417-431 Horn PA; Morris JC; Neff T; Kiem HP Stem cell gene transfer-efficacy and safety in large animal studies | 0 | 0 |
| 119 | 4 | 26 | 70 2004 SEP 17 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 322(2):672-677 Kulkarni A; Pavithra L; Rampalli S; Mogare D; Babu K; et al. HIV-1 integration sites are flanked by potential MARs that alone can act as promoters | 1 | 1 |
| 120 | 14 | 108 | 62 2004 OCT-DEC [OCT 15] AIDS REVIEWS 6(4):199-207 Lehmann-Che J; Saib A Early stages of HIV replication: How to hijack cellular functions for a successful infection | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 121 | 7 | 38 | 73 2004 OCT 15 BLOOD 104(8):2281-2290 Hanawa H; Hargrove PW; Kepes S; Srivastava DK; Nienhuis AW; et al. Extended beta-globin locus control region elements promote consistent therapeutic expression of a gamma-globin lentiviral vector in murine beta-thalassemia | 0 | 0 |
| 122 | 7 | 66 | 78 2004 OCT [15] CELLULAR AND MOLECULAR LIFE SCIENCES 61(19-20):2588-2596 Wu X; Burgess SM Integration target site selection for retroviruses and transposable elements | 0 | 0 |
| 123 | 3 | 38 | 88 2004 OCT [15] CURRENT OPINION IN MICROBIOLOGY 7(5):555-559 Trkola A HIV-host interactions: vital to the virus and key to its inhibition (vol 7, pg 555, 2004) | 1 | 1 |
| 124 | 7 | 54 | 98 2004 OCT [15] GENE THERAPY 11:S3-S9 Barquinero J; Eixarch H; Perez-Melgosa M Retroviral vectors: new applications for an old tool | 0 | 0 |
| 125 | 7 | 22 | 107 2004 OCT [15] JOURNAL OF CLINICAL INVESTIGATION 114(7):889-891 von Kalle C; Baum C; Williams DA Lenti in red: progress in gene therapy for human hemoglobinopathies | 0 | 0 |
| 126 | 3 | 73 | 108 2004 OCT [15] JOURNAL OF CLINICAL INVESTIGATION 114(7):953-962 Imren S; Fabry ME; Westerman KA; Pawliuk R; Tang P; et al. High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells | 1 | 1 |
| 127 | 2 | 50 | 113 2004 OCT 15 JOURNAL OF INFECTIOUS DISEASES 190(8):1429-1437 Ylisastigui L; Coull JJ; Rucker VC; Melander C; Bosch RJ; et al. Polyamides reveal a role for repression in latency within resting T cells of HIV-infected donors | 0 | 0 |
| 128 | 2 | 42 | 121 2004 OCT [15] JOURNAL OF VIROLOGY 78(19):10747-10754 Ciuffi A; Bleiber G; Munoz M; Martinez R; Loeuillet C; et al. Entry and transcription as key determinants of differences in CD4 T-cell permissiveness to human immunodeficiency virus type 1 infection | 0 | 0 |
| 129 | 5 | 34 | 130 2004 OCT [15] MOLECULAR THERAPY 10(4):660-670 Recchia A; Perani L; Sartori D; Olgiati C; Mavilio F Site-specific integration of functional transgenes into the human genome by adeno/AAV hybrid vectors | 0 | 0 |
| 130 | 8 | 138 | 138 2004 OCT [15] SEMINARS IN HEMATOLOGY 41(4):303-318 von Kalle C; Fehse B; Layh-Schmitt G; Schmidt M; Kelly P; et al. Stem cell clonality and genotoxicity in hematopoietic cells: Gene activation side effects should be avoidable | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 131 | 1 | 53 | 143 2004 NOV 10 VIROLOGY 329(1):77-88 Mannioui A; Schiffer C; Felix N; Nelson E; Brussel A; et al. Cell cycle regulation of human immunodeficiency virus type 1 integration in T cells: antagonistic effects of nuclear envelope breakdown and chromatin condensation | 0 | 0 |
| 132 | 4 | 105 | 99 2004 NOV [15] GENETICS 168(3):1159-1176 Aye M; Irwin B; Beliakova-Bethell N; Chen E; Garrus J; et al. Host factors that affect Ty3 retrotransposition in Saccharomyces cerevisiae | 0 | 0 |
| 133 | 7 | 39 | 115 2004 NOV [15] JOURNAL OF VIROLOGICAL METHODS 121(2):127-136 Hahm SH; Yi YS; Lee DK; Noh MJ; Yun L; et al. Construction of retroviral vectors with enhanced efficiency of transgene expression | 0 | 0 |
| 134 | 6 | 43 | 122 2004 NOV [15] JOURNAL OF VIROLOGY 78(21):11656-11663 Narezkina A; Taganov KD; Litwin S; Stoyanova R; Hayashi J; et al. Genome-wide analyses of avian sarcoma virus integration sites | 3 | 3 |
| 135 | 5 | 45 | 131 2004 NOV [15] MOLECULAR THERAPY 10(5):874-881 Laufs S; Nagy KZ; Giordano FA; Hotz-Wagenblatt A; Zeller WJ; et al. Insertion of retroviral vectors in NOD/SCID repopulating human peripheral blood progenitor cells occurs preferentially in the vicinity of transcription start regions and in introns | 0 | 0 |
| 136 | 6 | 79 | 141 2004 NOV [15] TRENDS IN MOLECULAR MEDICINE 10(11):525-531 Lassen K; Han YF; Zhou Y; Siliciano J; Siliciano RF The multifactorial nature of HIV-1 latency | 1 | 1 |
| 137 | 10 | 59 | 104 2004 NOV 19 JOURNAL OF BIOLOGICAL CHEMISTRY 279(47):48883-48892 Cherepanov P; Devroe E; Silver PA; Engelman A Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase | 0 | 0 |
| 138 | 6 | 41 | 74 2004 DEC 1 BLOOD 104(12):3445-3453 Puthenveetil G; Scholes J; Carbonell D; Oureshi N; Xia P; et al. Successful correction of the human beta-thalassemia major phenotype using a lentiviral vector | 0 | 0 |
| 139 | 1 | 91 | 67 2004 DEC [15] BEST PRACTICE & RESEARCH IN CLINICAL OBSTETRICS & GYNAECOLOGY 18(6):941-958 Flake AW In utero stem cell transplantation | 0 | 0 |
| 140 | 3 | 217 | 82 2004 DEC [15] CURRENT GENE THERAPY 4(4):357-372 Tomanin R; Scarpa M Why do we need new gene therapy viral vectors? Characteristics, limitations and future perspectives of viral vector transduction | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 141 | 7 | 53 | 136 2004 DEC [15] PLOS BIOLOGY 2(12):2183-2190 Hematti P; Hong BK; Ferguson C; Adler R; Hanawa H; et al. Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells | 0 | 0 |
| 142 | 4 | 58 | 139 2004 DEC [15] TRANSGENIC RESEARCH 13(6):513-522 Pfeifer A Lentiviral transgenesis | 0 | 0 |
| 143 | 2 | 33 | 93 2004 DEC 17 FEBS LETTERS 578(3):291-296 Boese A; Sommer P; Gaussin A; Reimann A; Nehrbass U Ini1/hSNF5 is dispensable for retrovirus-induced cytoplasmic accumulation of PML and does not interfere with integration | 0 | 0 |
| 144 | 6 | 48 | 105 2004 DEC 31 JOURNAL OF BIOLOGICAL CHEMISTRY 279(53):55570-55577 Llano M; Delgado S; Vanegas M; Poeschla EM Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase | 0 | 0 |
| 145 | 3 | 77 | 150 2005 JAN [15] JOURNAL OF VIROLOGY 79(1):67-78 Nielsen AA; Sorensen AB; Schmidt J; Pedersen FS Analysis of wild-type and mutant SL3-3 murine leukemia virus insertions in the c-myc promoter during lymphomagenesis reveals target site hot spots, virus-dependent patterns, and frequent error-prone gap repair | 0 | 0 |
| 146 | 4 | 10 | 155 2005 JAN [15] PLOS MEDICINE 2(1):22-24 Fischer A; Cavazzana-Calvo M Integration of retroviruses: A fine balance between efficiency and danger | 0 | 0 |
| 147 | 3 | 180 | 158 2005 JAN [15] SPRINGER SEMINARS IN IMMUNOPATHOLOGY 26(3):309-328 Larsson M HIV-1 and the hijacking of dendritic cells: a tug of war | 0 | 0 |
| 148 | 9 | 20 | 156 2005 FEB 1 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102(5):1275-1276 Engelman A The ups and downs of gene expression and retroviral DNA integration | 0 | 0 |
| 149 | 4 | 19 | 157 2005 FEB 1 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102(5):1436-1441 Maxfield LF; Fraize CD; Coffin JM Relationship between retroviral DNA-integration-site selection and host cell transcription | 1 | 1 |
| 150 | 5 | 114 | 146 2005 FEB [15] CURRENT GENE THERAPY 5(1):25-35 Yi Y; Hahm SH; Lee KH Retroviral gene therapy: Safety issues and possible solutions | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 151 | 4 | 69 | 147 2005 FEB [15] CURRENT GENE THERAPY 5(1):121-132 Qasim W; Gaspar HB; Thrasher AJ T cell suicide gene therapy to aid haematopoietic stem cell transplantation | 0 | 0 |
| 152 | 2 | 294 | 148 2005 FEB [15] CURRENT GENOMICS 6(1):13-37 Kremer EJ Gene transfer to the central nervous system: Current state of the art of the viral vectors | 0 | 0 |
| 153 | 2 | 72 | 151 2005 FEB [15] JOURNAL OF VIROLOGY 79(3):1645-1654 Leonard JN; Schaffer DV Computational design of antiviral RNA interference strategies that resist human immunodeficiency virus escape | 0 | 0 |
| 154 | 4 | 87 | 149 2005 MAR [15] CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT 8(2):199-206 Herzog RW Recent advances in hepatic gene transfer: More efficacy and less immunogenicity | 0 | 0 |
| 155 | 4 | 32 | 152 2005 MAR [15] JOURNAL OF VIROLOGY 79(6):3606-3614 Nakai H; Wu XL; Fuess S; Storm TA; Munroe D; et al. Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver | 0 | 0 |
| 156 | 9 | 63 | 153 2005 MAR [15] MOLECULAR AND CELLULAR BIOLOGY 25(6):2085-2094 Yant SR; Wu XL; Huang Y; Garrison B; Burgess SM; et al. High-resolution genome-wide mapping of transposon integration in mammals | 0 | 0 |
| 157 | 6 | 98 | 154 2005 MAR [15] NATURE REVIEWS DRUG DISCOVERY 4(3):236-248 Pommier Y; Johnson AA; Marchand C Integrase inhibitors to treat HIV/AIDS | 0 | 0 |
| 158 | 3 | 43 | 145 2005 APR 8 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 329(2):646-652 Chen ZYJ; Kren BT; Wong PYP; Low WC; Steer CJ Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference | 0 | 0 |
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