| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 1 | 0 | 1 2001 NATURE 414(6865):799-806
Saltiel AR; Kahn CR
Insulin signalling and the regulation of glucose and lipid metabolism | 136 | 136
|
| 2 | 1 | 2 2002 BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY 16(5):709-731
Haque M; Sanyal AJ
The metabolic abnormalities associated with non-alcoholic fatty liver disease | 0 | 0
|
| 3 | 1 | 3 2002 CELL 111(3):293-303
Brazil DP; Park J; Hemmings BA
PKB binding proteins: Getting in on the akt | 11 | 0
|
| 4 | 1 | 4 2002 CURRENT BIOLOGY 12(7):R236-R238
Lizcano JM; Alessi DR
The insulin signalling pathway | 6 | 1
|
| 5 | 1 | 5 2002 CURRENT BIOLOGY 12(15):1293-1300
Ikeya T; Galic M; Belawat P; Nairz K; Hafen E
Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila | 7 | 0
|
| 6 | 1 | 6 2002 CURRENT BIOLOGY 12(21):1871-1876
Tengholm A; Meyer T
A PI3-kinase signaling code for insulin-triggered insertion of glucose transporters into the plasma membrane | 4 | 0
|
| 7 | 1 | 7 2002 CURRENT MEDICINAL CHEMISTRY 9(24):2231-2242
Laborde E; Manchem VP
Small molecule activators of the insulin receptor: Potential new therapeutic agents for the treatment of diabetes mellitus | 0 | 0
|
| 8 | 1 | 8 2002 CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE 5(4):371-375
Le Roith D; Kim H; Fernandez AM; Accili D
Inactivation of muscle insulin and IGF-I receptors and insulin responsiveness | 0 | 0
|
| 9 | 1 | 9 2002 CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT 5(4):500-512
Tobin JF; Tam S
Recent advances in the development of small molecule inhibitors of PTP1B for the treatment of insulin resistance and type 2 diabetes | 4 | 0
|
| 10 | 1 | 10 2002 CURRENT OPINION IN GENETICS & DEVELOPMENT 12(5):565-571
Saucedo LJ; Edgar BA
Why size matters: altering cell size | 6 | 0
|
| 11 | 1 | 11 2002 CURRENT OPINION IN MOLECULAR THERAPEUTICS 4(3):236-241
Jurgens M; Schrader M
Peptidomic approaches in proteomic research | 1 | 0
|
| 12 | 2 | 12 2002 CURRENT SCIENCE 83(10):1190-1191
Ehtesham NZ
Does resistin resist insulin? | 2 | 0
|
| 13 | 1 | 13 2002 DIABETES 51():S434-S442
MacDonald PE; El-kholy W; Riedel MJ; Salapatek AMF; Light PE; Wheeler MB
The multiple actions of GLP-1 on the process of glucose- stimulated insulin secretion | 4 | 0
|
| 14 | 1 | 14 2002 DIABETES 51(9):2734-2741
Nishizawa H; Shimomura H; Kishida K; Maeda N; Kuriyama H; Nagaretani H; Matsuda M; Kondo H; Furuyama N; Kihara S; Nakamura T; Tochino Y; Funahashi T; Matsuzawa Y
Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein | 19 | 0
|
| 15 | 1 | 15 2002 DIABETES-METABOLISM RESEARCH AND REVIEWS 18(4):305-310
Ren J; Davidoff AJ
alpha 2-Heremans Schmid glycoprotein, a putative inhibitor of tyrosine kinase, prevents glucose toxicity associated with cardiomyocyte dysfunction | 1 | 0
|
| 16 | 2 | 16 2002 ENDOCRINE 19(3):257-266
Kulkarni RN; Okada T
Tissue-specific targeting of the insulin receptor gene | 0 | 0
|
| 17 | 1 | 17 2002 ENDOCRINOLOGY 143(10):3766-3772
Ribaux P; Gjinovci A; Sadowski HB; Iynedjian PB
Discrimination between signaling pathways in regulation of specific gene expression by insulin and growth hormone in hepatocytes | 0 | 0
|
| 18 | 1 | 18 2002 ENDOCRINOLOGY 143(11):4295-4303
Gavete ML; Agote M; Martin MA; Alvarez C; Escriva F
Effects of chronic undernutrition on glucose uptake and glucose transporter proteins in rat heart | 1 | 0
|
| 19 | 1 | 19 2002 ENDOCRINOLOGY 143(12):4563-4569
Shimizu S; Maegawa H; Egawa K; Shi K; Bryer-Ash M; Kashiwagi A
Mechanism for differential effect of protein-tyrosine phosphatase 1B on Akt versus mitogen-activated protein kinase in 3T3-L1 adipocytes | 1 | 0
|
| 20 | 1 | 20 2002 GENES & DEVELOPMENT 16(17):2286-2299
Prober DA; Edgar BA
Interactions between Ras1, dMyc, and dPI3K signaling in the developing Drosophila wing | 9 | 0
|
| 21 | 1 | 21 2002 GENES & DEVELOPMENT 16(24):3213-3222
Laustsen PG; Michael MD; Crute BE; Cohen SE; Ueki K; Kulkarni RN; Keller SR; Lienhard GE; Kahn CR
Lipoatrophic diabetes in Irs1(-/-)/Irs3(-/-) double knockout mice | 2 | 0
|
| 22 | 1 | 22 2002 GLUCOSE METABOLISM IN THE BRAIN 51():103-158
Heininger K
The cerebral glucose-fatty acid cycle: Evolutionary roots, regulation, and (patho) physiological importance | 0 | 0
|
| 23 | 1 | 23 2002 HORMONE AND METABOLIC RESEARCH 34(11-12):650-654
Fisher FM; McTernan PG; Valsamakis G; Chetty R; Harte AL; Anwar AJ; Starcynski J; Crocker J; Barnett AH; McTernan CL; Kumar S
Differences in adiponectin protein expression: Effect of fat depots and type 2 diabetic status | 1 | 0
|
| 24 | 1 | 24 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(11):9133-9138
Kupriyanova TA; Kandror V; Kandror KV
Isolation and characterization of the two major intracellular Glut4 storage compartments | 5 | 0
|
| 25 | 1 | 25 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(25):22581-22589
Kiely PA; Sant A; O'Connor R
RACK1 is an insulin-like growth factor 1 (IGF-1) receptor- interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death | 8 | 0
|
| 26 | 1 | 26 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(28):25233-25238
Hresko RC; Mueckler M
Identification of pp68 as the tyrosine-phosphorylated form of SYNCRIP/NSAP1 - A cytoplasmic RNA-binding protein | 1 | 0
|
| 27 | 1 | 27 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(31):27975-27981
Treins C; Giorgetti-Peraldi S; Murdaca J; Semenza GL; Van Obberghen E
Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway | 22 | 2
|
| 28 | 1 | 28 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(33):30153-30158
Kimura A; Mora S; Shigematsu S; Pessin JE; Saltiel AR
The insulin receptor catalyzes the tyrosine phosphorylation of caveolin-1 | 5 | 0
|
| 29 | 1 | 29 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(46):43545-43548
Notkins AL
Immunologic and genetic factors in type 1 diabetes | 1 | 1
|
| 30 | 1 | 30 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(46):44278-44284
Lin DH; Sterling H; Lerea KM; Giebisch G; Wang WH
Protein kinase C (PKC)-induced phosphorylation of ROMK1 is essential for the surface expression of ROMK1 channels | 1 | 0
|
| 31 | 1 | 31 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(50):48115-48121
Gao ZG; Hwang D; Bataille F; Lefevre M; York D; Quon M; Ye JP
Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex | 11 | 3
|
| 32 | 1 | 32 2002 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 87(6):2474-2480
Goldstein BJ
Protein-tyrosine phosphatases: Emerging targets for therapeutic intervention in type 2 diabetes and related states of insulin resistance | 7 | 1
|
| 33 | 1 | 33 2002 JOURNAL OF CLINICAL INVESTIGATION 109(9):1193-1201
Kushner JA; Ye J; Schubert M; Burks DJ; Dow MA; Flint CL; Dutta S; Wright CVE; Montminy MR; White MF
Pdx1 restores beta cell function in Irs2 knockout mice | 12 | 1
|
| 34 | 2 | 34 2002 JOURNAL OF CLINICAL INVESTIGATION 110(12):1839-1847
Kitamura T; Nakae J; Kitamura Y; Kido Y; Biggs WH; Wright CVE; White MF; Arden KC; Accili D
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth | 4 | 1
|
| 35 | 1 | 35 2002 JOURNAL OF ENDOCRINOLOGY 175(3):727-733
Fasshauer M; Klein J; Lossner U; Paschke R
Isoproterenol is a positive regulator of the suppressor of cytokine signaling-3 gene expression in 3T3-L1 adipocytes | 1 | 0
|
| 36 | 1 | 36 2002 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 34(9):1091-1097
Hue L; Beauloye C; Marsin AS; Bertrand L; Horman S; Rider MH
Insulin and ischemia stimulate glycolysis by acting on the same targets through different and opposing signaling pathways | 2 | 1
|
| 37 | 1 | 37 2002 LABORATORY INVESTIGATION 82(9):1155-1166
Piguet PF; Da Kan C; Vesin C
Role of the tumor necrosis factor receptor 2 (TNFR2) in cerebral malaria in mice | 1 | 0
|
| 38 | 1 | 38 2002 MICROSCOPY RESEARCH AND TECHNIQUE 59(4):317-324
Chiba T; Yamaza H; Higami Y; Shimokawa I
Anti-aging effects of caloric restriction: Involvement of neuroendocrine adaptation by peripheral signaling | 1 | 0
|
| 39 | 1 | 39 2002 MOLECULAR BIOLOGY OF THE CELL 13(11):3943-3954
Shumay E; Song XS; Wang HY; Malbon CC
pp60Src mediates insulin-stimulated sequestration of the beta(2)-adrenergic receptor: Insulin stimulates pp60Src phosphorylation and activation | 0 | 0
|
| 40 | 1 | 40 2002 NACHRICHTEN AUS DER CHEMIE 50(5):590-595
Schultz C; Dinkel C
Phosphatidylinosites: Information sources of the other type | 0 | 0
|
| 41 | 1 | 41 2002 NATURE 420(6913):333-336
Hirosumi J; Tuncman G; Chang LF; Gorgun CZ; Uysal KT; Maeda K; Karin M; Hotamisligil GS
A central role for JNK in obesity and insulin resistance | 28 | 4
|
| 42 | 1 | 42 2002 NATURE 420(6917):821-824
Bose A; Guilherme A; Robida SI; Nicoloro SMC; Zhou QL; Jiang ZY; Pomerleau DP; Czech MP
Glucose transporter recycling in response to insulin is facilitated by myosin Myo1c | 2 | 0
|
| 43 | 1 | 43 2002 NATURE MEDICINE 8(7):731-737
Maeda N; Shimomura I; Kishida K; Nishizawa H; Matsuda M; Nagaretani H; Furuyama N; Kondo H; Takahashi M; Arita Y; Komuro R; Ouchi N; Kihara S; Tochino Y; Okutomi K; Horie M; Takeda S; Aoyama T; Funahashi T; Matsuzawa Y
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30 | 70 | 4
|
| 44 | 1 | 44 2002 NATURE REVIEWS DRUG DISCOVERY 1(9):696-709
Johnson TO; Ermolieff J; Jirousek MR
Protein tyrosine phosphatase 1B inhibitors for diabetes | 14 | 2
|
| 45 | 1 | 45 2002 ONCOGENE 21(46):7131-7136
Viniegra JG; Losa JH; Sanchez-Arevalo VJ; Cobo CP; Soria VMF; Cajal SRY; Sanchez-Prieto R
Modulation of PI3K/Akt pathway by E1a mediates sensitivity to cisplatin | 2 | 0
|
| 46 | 1 | 46 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(12):8301-8305
Danesh FR; Sadeghi MM; Amro N; Philips C; Zeng LX; Lin S; Sahai A; Kanwar YS
3-hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/p21 signaling pathway: Implications for diabetic nephropathy | 10 | 0
|
| 47 | 1 | 47 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(16):10587-10592
Yechoor VK; Patti ME; Saccone R; Kahn CR
Coordinated patterns of gene expression for substrate and energy metabolism in skeletal muscle of diabetic mice | 4 | 1
|
| 48 | 1 | 48 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(25):16105-16110
Hori Y; Rulifson IC; Tsai BC; Heit JJ; Cahoy JD; Kim SK
Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells | 8 | 0
|
| 49 | 1 | 49 2002 SWISS MEDICAL WEEKLY 132(19-20):241-252
Kohler HP
Insulin resistance syndrome: interaction with coagulation and fibrinolysis | 3 | 0
|
| 50 | 1 | 50 2002 TRENDS IN BIOCHEMICAL SCIENCES 27(7):352-360
Burgering BMT; Kops GJPL
Cell cycle and death control: long live Forkheads | 22 | 0
|
| 51 | 1 | 51 2002 TRENDS IN ENDOCRINOLOGY AND METABOLISM 13(6):240-245
Najjar SM
Regulation of insulin action by CEACAM1 | 1 | 0
|
| 52 | 1 | 52 2003 AMERICAN JOURNAL OF CARDIOLOGY 92(4A):3J-9J
Hsueh WA; Law R
The central role of fat and effect of peroxisome proliferatorm- activated receptor-gamma on progression of insulin resistance and cardiovascular disease | 1 | 0
|
| 53 | 1 | 53 2003 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 285(1):C222-C235
Cohen AW; Razani B; Wang XB; Combs TP; Williams TM; Scherer PE; Lisanti MP
Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue | 0 | 0
|
| 54 | 1 | 54 2003 AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 284(4):E655-E662
Crowther GJ; Milstein JM; Jubrias SA; Kushmerick MJ; Gronka RK; Conley KE
Altered energetic properties in skeletal muscle of men with well-controlled insulin-dependent (type 1) diabetes | 0 | 0
|
| 55 | 2 | 55 2003 AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 284(4):E663-E670
Asante-Appiah E; Kennedy BP
Protein tyrosine phosphatases: the quest for negative regulators of insulin action | 0 | 0
|
| 56 | 1 | 56 2003 AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 284(5):E863-E873
Lam TKT; Carpentier A; Lewis GF; van de Werve G; Fantus IG; Giacca A
Mechanisms of the free fatty acid-induced increase in hepatic glucose production | 2 | 1
|
| 57 | 1 | 57 2003 AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 285(2):E303-E310
Rachdaoui N; Sebastian BM; Nagy LE
Chronic ethanol feeding impairs endothelin-1-stimulated glucose uptake via decreased G alpha(11) expression in rat adipocytes | 1 | 0
|
| 58 | 2 | 58 2003 AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 285(4):E685-E692
Barthel A; Schmoll D
Novel concepts in insulin regulation of hepatic gluconeogenesis | 0 | 0
|
| 59 | 1 | 59 2003 ANNUAL REVIEW OF PHYSIOLOGY 65():313-332
Kitamura T; Kahn CR; Accili E
Insulin receptor knockout mice | 1 | 0
|
| 60 | 2 | 60 2003 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 416(2):164-170
Maebuchi M; Machidori M; Urade R; Ogawa T; Moriyama T
Low resistin levels in adipose tissues and serum in high-fat fed mice and genetically obese mice: development of an ELISA system for quantification of resistin | 0 | 0
|
| 61 | 1 | 61 2003 AVIATION SPACE AND ENVIRONMENTAL MEDICINE 74(10):1091-1100
Steinkraus LW; Cayce W; Golding A
Diabetes mellitus type 2 in aviators: A preventable disease | 0 | 0
|
| 62 | 1 | 62 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 300(2):261-267
Clampit JE; Meuth JL; Smith HT; Reilly RM; Jirousek MR; Trevillyan JM; Rondinone CM
Reduction of protein-tyrosine phosphatase-1B increases insulin signaling in FAO hepatoma cells | 0 | 0
|
| 63 | 1 | 63 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 304(2):399-404
Lee HJ; Koh GY
Shear stress activates Tie2 receptor tyrosine kinase in human endothelial cells | 0 | 0
|
| 64 | 1 | 64 2003 BIOCHEMICAL PHARMACOLOGY 65(2):249-257
Kumar N; Dey CS
Development of insulin resistance and reversal by thiazolidinediones in C2C12 skeletal muscle cells | 0 | 0
|
| 65 | 1 | 65 2003 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 13(11):1887-1890
Xin ZL; Oost TK; Abad-Zapatero C; Hajduk PJ; Pei ZH; Szczepankiewicz BG; Hutchins CW; Ballaron SJ; Stashko MA; Lubben T; Trevillyan JM; Jirousek MR; Liu G
Potent, selective inhibitors of protein tyrosine phosphatase 1B | 3 | 0
|
| 66 | 2 | 66 2003 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 13(19):3129-3132
Pei ZH; Li XF; Liu G; Abad-Zapatero C; Lubben T; Zhang TY; Ballaron SJ; Hutchins CW; Trevillyan JM; Jirouseka MR
Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors | 0 | 0
|
| 67 | 1 | 67 2003 BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 67(6):1272-1277
Asai Y; Yamada K; Watanabe T; Keng VW; Noguchi T
Insulin stimulates expression of the pyruvate kinase m gene in 3T3-L1 adipocytes | 0 | 0
|
| 68 | 2 | 68 2003 BLOOD 101(3):907-914
Kietzmann T; Samoylenko A; Roth U; Jungermann K
Hypoxia-inducible factor-1 and hypoxia response elements mediate the induction of plasminogen activator inhibitor-1 gene expression by insulin in primary rat hepatocytes | 1 | 0
|
| 69 | 2 | 69 2003 CELL 113(2):144-145
Saltiel AR
Muscle or fat? Rho bridges the GAP | 0 | 0
|
| 70 | 1 | 70 2003 CIRCULATION 108(13):1541-1545
Haffner S; Taegtmeyer H
Epidemic obesity and the metabolic syndrome | 1 | 0
|
| 71 | 1 | 71 2003 CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 30(9):643-648
Xie P; Liu ML; Gu YP; Lu J; Xu X; Zeng WM; Song HP
Oestrogen improves glucose metabolism and insulin signal transduction in HEPG2 cells | 0 | 0
|
| 72 | 1 | 72 2003 CLINICAL CHEMISTRY AND LABORATORY MEDICINE 41(9):1266-1278
Dominiczak MH
Obesity, glucose intolerance and diabetes and their links to cardiovascular disease. Implications for laboratory medicine | 0 | 0
|
| 73 | 1 | 73 2003 CLINICAL ENDOCRINOLOGY 59(3):267-277
Gurnell M
PPAR gamma and metabolism: insights from the study of human genetic variants | 0 | 0
|
| 74 | 1 | 74 2003 COORDINATION CHEMISTRY REVIEWS 237(1-2):13-22
Crans DC; Yang LQ; Alfano JA; Chi LAH; Jin WZ; Mahroof-Tahir M; Robbins K; Toloue MM; Chan LK; Plante AJ; Grayson RZ; Willsky GR
(4-hydroxypyridine-2,6-dicarboxylato)oxovanadate(V) - a new insulin-like compound: chemistry, effects on myoblast and yeast cell growth and effects on hyperglycemia in rats with STZ- induced diabetes | 0 | 0
|
| 75 | 1 | 75 2003 CRITICAL CARE MEDICINE 31(2):634-635
Annane D; Melchior JC
Hormone replacement therapy for the critically ill | 1 | 0
|
| 76 | 2 | 76 2003 CURRENT BIOLOGY 13(14):R574-R576
Kanzaki M; Pessin JE
Insulin signaling: GLUT4 vesicles exit via the exocyst | 0 | 0
|
| 77 | 1 | 77 2003 CURRENT DRUG TARGETS 4(6):493-503
Stentz FB; Kitabchi AE
Activated T lymphocytes in type 2 diabetes: Implications from in vitro studies | 0 | 0
|
| 78 | 1 | 78 2003 CURRENT PHARMACEUTICAL DESIGN 9(15):1177-1189
Somsak L; Nagy V; Hadady Z; Docsa T; Gergely P
Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: Recent developments | 1 | 0
|
| 79 | 1 | 79 2003 CURRENT TOPICS IN MEDICINAL CHEMISTRY 3(7):749-757
Ramachandran C
Protein tyrosine phosphatase 1B: A novel target for type 2 diabetes and obesity | 0 | 0
|
| 80 | 1 | 80 2003 DIABETES 52(5):1280-1283
Sesti G; Cardellini M; Marini MA; Frontoni S; D'Adamo M; Del Guerra S; Lauro D; De Nicolais P; Sbraccia P; Del Prato S; Gambardella S; Federici M; Marchetti P; Lauro R
A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects | 0 | 0
|
| 81 | 1 | 81 2003 DIABETES 52(8):1943-1950
Miyazaki Y; He H; Mandarino LJ; DeFronzo RA
Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients | 0 | 0
|
| 82 | 1 | 82 2003 DIABETES 52(8):2129-2136
Huang TJ; Price SA; Chilton L; Calcutt NA; Tomlinson DR; Verkhratsky A; Fernyhough P
Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia | 0 | 0
|
| 83 | 1 | 83 2003 DIABETES 52(10):2554-2561
Borradaile NM; de Dreu LE; Huff MW
Inhibition of net HepG2 cell apolipoprotein B secretion by the citrus flavonoid naringenin involves activation of phosphatidylinositol 3-kinase, independent of insulin receptor substrate-1 phosphorylation | 0 | 0
|
| 84 | 1 | 84 2003 DIABETOLOGIA 46(7):990-995
Jellema A; Zeegers MPA; Feskens EJM; Dagnelie PC; Mensink RP
Gly972Arg variant in the insulin receptor substrate-1 gene and association with Type 2 diabetes: a meta-analysis of 27 studies | 0 | 0
|
| 85 | 1 | 85 2003 EMBO JOURNAL 22(11):2679-2691
Chiang SH; Hwang J; Legendre M; Zhang M; Kimura A; Saltiel AR
TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport | 0 | 0
|
| 86 | 2 | 86 2003 EMBO JOURNAL 22(18):4666-4676
Mora A; Davies AM; Bertrand L; Sharif I; Budas GR; Jovanovic S; Mouton V; Kahn CR; Lucocq JM; Gray GA; Jovanovic A; Alessi DR
Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia | 0 | 0
|
| 87 | 1 | 87 2003 ENDOCRINE REVIEWS 24(1):91-101
Shi YG; Taylor SI; Tan SL; Sonenberg N
When translation meets metabolism: Multiple links to diabetes | 0 | 0
|
| 88 | 1 | 88 2003 ENDOCRINOLOGY 144(8):3456-3462
Voshol PJ; Haemmerle G; Ouwens DM; Zimmermann R; Zechner R; Teusink B; Maassen JA; Havekes LM; Romijn JA
Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase- deficient mice | 0 | 0
|
| 89 | 2 | 89 2003 EUROPEAN JOURNAL OF BIOCHEMISTRY 270(5):791-798
Bilton RL; Booker GW
The subtle side to hypoxia inducible factor (HIF alpha) regulation | 1 | 0
|
| 90 | 1 | 90 2003 EUROPEAN JOURNAL OF BIOCHEMISTRY 270(13):2773-2781
Aiston S; Coghlan MP; Agius L
Inactivation of phosphorylase is a major component of the mechanism by which insulin stimulates hepatic glycogen synthesis | 0 | 0
|
| 91 | 1 | 91 2003 FASEB JOURNAL 17(8):U552-U575
Hribal ML; Perego L; Lovari S; Andreozzi F; Menghini R; Perego C; Finzi G; Usellini L; Placidi C; Capella C; Guzzi V; Lauro D; Bertuzzi F; Davalli A; Pozza G; Pontiroli A; Federici M; Lauro R; Brunetti A; Folli F; Sesti G
Chronic hyperglycemia impairs insulin secretion by affecting insulin receptor expression, splicing, and signaling in RIN beta-cell line and human islets of Langerhans | 0 | 0
|
| 92 | 2 | 92 2003 GENES & DEVELOPMENT 17(7):813-818
Nelson DW; Padgett RW
Insulin worms its way into the spotlight | 0 | 0
|
| 93 | 1 | 93 2003 GENES & DEVELOPMENT 17(19):2450-2464
Verheijen MHG; Chrast R; Burrola P; Lemke G
Local regulation of fat metabolism in peripheral nerves | 0 | 0
|
| 94 | 1 | 94 2003 HYPERTENSION 41(3):763-767
Rahmouni K; Haynes WG; Morgan DA; Mark AL
Intracellular mechanisms involved in leptin regulation of sympathetic outflow | 1 | 0
|
| 95 | 1 | 95 2003 INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY 84(2):83-89
Pickavance LC; Widdowson PS; Foster JR; Williams G; Wilding JPH
Chronic treatment with the thiazolidinedione, MCC-555, is associated with reductions in nitric oxide synthase activity and beta-cell apoptosis in the pancreas of the Zucker Diabetic Fatty rat | 0 | 0
|
| 96 | 1 | 96 2003 JOURNAL OF APPLIED PHYSIOLOGY 94(6):2127-2134
Gauthier MS; Couturier K; Latour JG; Lavoie JM
Concurrent exercise prevents high-fat-diet-induced macrovesicular hepatic steatosis | 0 | 0
|
| 97 | 2 | 97 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(5):2896-2902
Lee YH; Giraud J; Davis RJ; White MF
c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade | 8 | 1
|
| 98 | 1 | 98 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(12):10022-10027
Parker GJ; Lund KC; Taylor RP; McClain DA
Insulin resistance of glycogen synthase mediated by O-linked N- acetylglucosamine | 3 | 0
|
| 99 | 1 | 99 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(20):18440-18447
Horike N; Takemori H; Katoh Y; Doi J; Min L; Asano T; Sun XJ; Yamamoto H; Kasayama S; Muraoka M; Nonaka Y; Okamoto M
Adipose-specific expression, phosphorylation of Ser(794) in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2 | 1 | 0
|
| 100 | 1 | 100 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(24):21607-21614
Murata H; Hresko RC; Mueckler M
Reconstitution of phosphoinositide 3-kinase-dependent insulin signaling in a cell-free system | 2 | 1
|
| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 101 | 2 | 101 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(24):21615-21622
Hresko RC; Murata H; Mueckler M
Phosphoinositide-dependent kinase-2 is a distinct protein kinase enriched in a novel cytoskeletal fraction associated with adipocyte plasma membranes | 0 | 0
|
| 102 | 4 | 102 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(27):24944-24950
Gao ZG; Zuberi A; Quon MJ; Dong ZG; Ye JP
Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in tumor necrosis factor-treated cells through targeting multiple serine kinases | 0 | 0
|
| 103 | 2 | 103 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(29):26550-26557
Gual P; Gonzalez T; Gremeaux T; Barres R; Le Marchand-Brustel Y; Tanti JF
Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes | 0 | 0
|
| 104 | 3 | 104 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(31):28359-28362
Okamoto H; Accili D
In vivo mutagenesis of the insulin receptor | 0 | 0
|
| 105 | 1 | 105 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(33):30835-30842
Greenberg CC; Meredith KN; Yan LM; Brady MJ
Protein targeting to glycogen overexpression results in the specific enhancement of glycogen storage in 3T3-L1 adipocytes | 0 | 0
|
| 106 | 1 | 106 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(33):30843-30848
Lin JD; Tarr PT; Yang RJ; Rhee J; Puigserver P; Newgard CB; Spiegelman BM
PGC-1 beta in the regulation of hepatic glucose and energy metabolism | 0 | 0
|
| 107 | 1 | 107 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(36):33609-33612
Minokoshi Y; Kahn CR; Kahn BB
Tissue-specific ablation of the GLUT4 glucose transporter or the insulin receptor challenges assumptions about insulin action and glucose homeostasis | 0 | 0
|
| 108 | 1 | 108 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(40):38796-38802
Sekoguchi E; Sato N; Yasui A; Fukada S; Nimura Y; Aburatani H; Ikeda K; Matsuura A
A novel mitochondrial carnitine-acylcarnitine translocase induced by partial hepatectomy and fasting | 0 | 0
|
| 109 | 1 | 109 2003 JOURNAL OF CARDIOVASCULAR RISK 10(2):121-128
Ginsberg HN; Stalenhoef AFH
The metabolic syndrome: targeting dyslipidaemia to reduce coronary risk | 0 | 0
|
| 110 | 1 | 110 2003 JOURNAL OF CELLULAR PHYSIOLOGY 196(1):89-97
Serra C; Federici M; Buongiorno A; Senni MI; Morelli S; Segratella E; Pascuccio M; Tiveron C; Mattei E; Tatangelo L; Lauro R; Molinaro M; Giaccari A; Bouche M
Transgenic mice with dominant negative PKC-theta in skeletal muscle: A new model of insulin resistance and obesity | 0 | 0
|
| 111 | 1 | 111 2003 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 88(1):317-322
D'Alfonso R; Marini MA; Frittitta L; Sorge R; Frontoni S; Porzio O; Mariani LM; Lauro D; Gambardella S; Trischitta V; Federici M; Lauro R; Sesti G
Polymorphisms of the insulin receptor subtrate-2 in patients with type 2 diabetes | 0 | 0
|
| 112 | 1 | 112 2003 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 88(2):627-636
Addy CL; Gavrila A; Tsiodras S; Brodovicz K; Karchmer AW; Mantzoros CS
Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy | 5 | 0
|
| 113 | 1 | 113 2003 JOURNAL OF EXPERIMENTAL MEDICINE 198(6):877-888
Matsuki T; Horai R; Sudo K; Iwakura Y
IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditions | 0 | 0
|
| 114 | 1 | 114 2003 JOURNAL OF INORGANIC BIOCHEMISTRY 95(1):1-13
Jakusch T; Jin WZ; Yang LQ; Kiss T; Crans DC
Vanadium(IV/V) speciation of pyridine-2,6-dicarboxylic acid and 4-hydroxy-pyridine-2,6-dicarboxylic acid complexes: potentiometry, EPR spectroscopy and comparison across oxidation states | 0 | 0
|
| 115 | 1 | 115 2003 JOURNAL OF NUCLEAR CARDIOLOGY 10(3):311-323
Bajaj M; DeFronzo RA
Metabolic and molecular basis of insulin resistance | 0 | 0
|
| 116 | 1 | 116 2003 JOURNAL OF SURGICAL RESEARCH 109(2):92-100
Madibally SV; Solomon V; Mitchell RN; Van De Water L; Yarmush ML; Toner M
Influence of insulin therapy on burn wound healing in rats | 1 | 0
|
| 117 | 1 | 117 2003 KIDNEY INTERNATIONAL 64(1):63-70
Lewin E; Garfia B; Almaden Y; Rodriguez M; Olgaard K
Autoregulation in the parathyroid glands by PTH/PTHrP receptor ligands in normal and uremic rats | 0 | 0
|
| 118 | 1 | 118 2003 LIFE SCIENCES 73(11):1369-1381
Hirata AE; Alvarez-Rojas F; Carvalheira JBC; Carvalho CRD; Dolnikoff MS; Saad MJA
Modulation of IR/PTP1B interaction and downstream signaling in insulin sensitive tissues of MSG-rats | 0 | 0
|
| 119 | 2 | 119 2003 M S-MEDECINE SCIENCES 19(8-9):834-839
Capeau J
Insulin signaling: Mechanisms altered in insulin resistance | 0 | 0
|
| 120 | 1 | 120 2003 MECHANISMS OF AGEING AND DEVELOPMENT 124(7):819-827
Dominici FP; Argentino DP; Bartke A; Turyn D
The dwarf mutation decreases high dose insulin responses in skeletal muscle, the opposite of effects in liver | 0 | 0
|
| 121 | 2 | 121 2003 METABOLISM-CLINICAL AND EXPERIMENTAL 52(6):705-712
Wu XD; Hardy VE; Joseph JI; Jabbour S; Mahadev K; Zhu L; Goldstein BJ
Tyrosine phosphatase activity in human adipocytes is strongly correlated with insulin-stimulated glucose uptake and is a target of insulin-induced oxidative inhibition | 0 | 0
|
| 122 | 1 | 122 2003 METABOLISM-CLINICAL AND EXPERIMENTAL 52(8):987-992
Papineau D; Gagnon AM; Sorisky A
Apoptosis of human abdominal preadipocytes before and after differentiation into adipocytes in culture | 0 | 0
|
| 123 | 2 | 123 2003 MOLECULAR & CELLULAR PROTEOMICS 2(6):399-404
Korc M
Diabetes mellitus in the era of proteomics | 0 | 0
|
| 124 | 1 | 124 2003 MOLECULAR AND CELLULAR BIOLOGY 23(6):2096-2108
Galic S; Klingler-Hoffmann M; Fodero-Tavoletti MT; Puryer MA; Meng TC; Tonks NK; Tiganis T
Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP | 0 | 0
|
| 125 | 1 | 125 2003 MOLECULAR AND CELLULAR BIOLOGY 23(8):2720-2732
Foti D; Iuliano R; Chiefari E; Brunetti A
A nucleoprotein complex containing sp1, C/EBP beta, and HMGI-Y controls human insulin receptor gene transcription | 0 | 0
|
| 126 | 2 | 126 2003 MOLECULAR AND CELLULAR BIOLOGY 23(17):6255-6266
Li Y; Eitan S; Wu J; Evans CJ; Kieffer B; Sun XJ; Polakiewicz RD
Morphine induces desensitization of insulin receptor signaling | 0 | 0
|
| 127 | 1 | 127 2003 NATURE 422(6932):629-633
Inoue M; Chang L; Hwang J; Chiang SH; Saltiel AR
The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin | 6 | 1
|
| 128 | 1 | 128 2003 NATURE REVIEWS DRUG DISCOVERY 2(5):340-340
Brazil M
GPR40 no longer an orphan | 0 | 0
|
| 129 | 1 | 129 2003 OBESITY RESEARCH 11(4):586-590
Yang WS; Lee WJ; Huang KC; Lee KC; Chao CL; Chen CL; Tai TY; Chuang LM
mRNA level of the insulin-signaling molecule SORBS1 in the adipose depots of nondiabetic women | 0 | 0
|
| 130 | 1 | 130 2003 ORGANIC LETTERS 5(3):255-257
Schlueter U; Lu J; Fraser-Reid B
Synthetic approaches to heavily lipidated phosphoglyceroinositides | 0 | 0
|
| 131 | 1 | 131 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(6):3445-3449
Yamashita T; Hashiramoto A; Haluzik M; Mizukami H; Beck S; Norton A; Kono M; Tsuji S; Daniotti JL; Werth N; Sandhoff R; Sandhoff K; Proia RL
Enhanced insulin sensitivity in mice lacking ganglioside GM3 | 1 | 0
|
| 132 | 1 | 132 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(11):6825-6830
Conarello SL; Li ZH; Ronan J; Roy RS; Zhu L; Jiang GQ; Liu F; Woods J; Zycband E; Moller DE; Thornberry NA; Zhang BB
Mice lacking dipeptidyl peptidase IV are protected against obesity and insulin resistance | 2 | 0
|
| 133 | 2 | 133 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(14):8466-8471
Patti ME; Butte AJ; Crunkhorn S; Cusi K; Berria R; Kashyap S; Miyazaki Y; Kohane I; Costello M; Saccone R; Landaker EJ; Goldfine AB; Mun E; DeFronzo R; Finlayson J; Kahn CR; Mandarino LJ
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1 | 1 | 0
|
| 134 | 1 | 134 2003 REPRODUCTION 126(1):91-99
Augustin R; Pocar P; Wrenzycki C; Niemann H; Fischer B
Mitogenic and anti-apoptotic activity of insulin on bovine embryos produced in vitro | 0 | 0
|
| 135 | 1 | 135 2003 TRENDS IN CELL BIOLOGY 13(2):79-85
Oldham S; Hafen E
Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control | 7 | 1
|
| 136 | 2 | 136 2003 TRENDS IN ENDOCRINOLOGY AND METABOLISM 14(4):169-175
Morral N
Novel targets and therapeutic strategies for type 2 diabetes | 0 | 0
|
| 137 | 1 | 137 2003 TRENDS IN ENDOCRINOLOGY AND METABOLISM 14(5):214-221
Agarwal AK; Garg A
Congenital generalized lipodystrophy: significance of triglyceride biosynthetic pathways | 0 | 0
|