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Fri Oct 31 14:51:10 2003
Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon
Lykke-Andersen J, Shu MD, Steitz JA
CELL
103 (7): 1121-1131 DEC 22 2000
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101 2000 CELL 103(7):1121-1131
LykkeAndersen J; Shu MD; Steitz JA
Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon
7979
222 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(5):989-1001
Schwarze U; Schievink WI; Petty E; Jaff MR; Babovic-Vuksanovic D; Cherry KJ; Pepin M; Byers PH
Haploinsufficiency for one COL3A1 allele of type III procollagen results in a phenotype similar to the vascular form of Ehlers-Danlos syndrome, Ehlers-Danlos syndrome type IV
60
323 2001 BIOFACTORS 14(1-4):37-42
Maquat LE
Evidence that selenium deficiency results in the cytoplasmic decay of GPx1 mRNA dependent on pre-mRNA splicing proteins bound to the mRNA exon-exon junction
30
414 2001 CELL 104(2):173-176
Maquat LE; Carmichael GG
Quality control of mRNA function
9618
535 2001 CELL 106(5):607-617
Ishigaki Y; Li XJ; Serin G; Maquat LE
Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20
4514
676 2001 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 66():313-320
Maquat LE; Serin G
Nonsense-mediated mRNA decay: Insights into mechanism from the cellular abundance of human Upf1, Upf2, Upf3, and Upf3X proteins
11
747 2001 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 66():321-328
Gonzalez CI; Wang W; Peltz SW
Nonsense-mediated mRNA decay in Saccharomyces cerevisiae: A quality control mechanism that degrades transcripts harboring premature termination codons
00
818 2001 CURRENT BIOLOGY 11(3):R88-R91
Lykke-Andersen J
mRNA quality control: Marking the message for life or death
410
919 2001 CURRENT OPINION IN CELL BIOLOGY 13(3):320-325
Mitchell P; Tollervey D
MRNA turnover
315
10110 2001 EMBO JOURNAL 20(4):880-890
Wang WR; Czaplinski K; Rao Y; Peltz SW
The role of Upf proteins in modulating the translation read- through of nonsense-containing transcripts
3520
11111 2001 EMBO JOURNAL 20(17):4987-4997
Le Hir H; Gatfield D; Izaurralde E; Moore MJ
The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay
830
12212 2001 EMBO JOURNAL 20(22):6424-6433
Kataoka N; Diem MD; Kim VN; Yong J; Dreyfuss G
Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex
307
13113 2001 FEBS LETTERS 498(2-3):157-163
Gama-Carvalho M; Carmo-Fonseca M
The rules and roles of nucleocytoplasmic shuttling proteins
110
14114 2001 GENE 268(1-2):153-164
Aronoff R; Baran R; Hodgkin J
Molecular identification of smg-4, required for mRNA surveillance in C. elegans
66
15315 2001 GENE 274(1-2):15-25
Gonzalez CI; Bhattacharya A; Wang WR; Peltz SW
Nonsense-mediated mRNA decay in Saccharomyces cerevisiae
213
16316 2001 GENES & DEVELOPMENT 15(17):2215-2228
Yamashita A; Ohnishi T; Kashima I; Taya Y; Ohno S
Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay
1712
17617 2001 GENES & DEVELOPMENT 15(21):2781-2785
Wilusz CJ; Wang WR; Peltz SW
Curbing the nonsense: the activation and regulation of mRNA surveillance
245
18218 2001 JOURNAL OF IMMUNOLOGY 167(12):6901-6911
Watanabe Y; Magor KE; Parham P
Exon 5 encoding the transmembrane region of HLA-A contains a transitional region for the induction of nonsense-mediated mRNA decay
30
19119 2001 MOLECULAR CELL 8(2):383-396
Mazza C; Ohno M; Segref A; Mattaj IW; Cusack S
Crystal structure of the human nuclear cap binding complex
100
20320 2001 MOLECULES AND CELLS 12(1):1-10
Kim VN; Dreyfuss G
Nuclear mRNA binding proteins couple pre-mRNA splicing and post-splicing events
60
21121 2001 NATURE BIOTECHNOLOGY 19(5):413-414
Culbertson MR
Sense versus nonsense in DNA diagnostics
21
22222 2001 NATURE REVIEWS MOLECULAR CELL BIOLOGY 2(4):237-246
Wilusz CJ; Wormington M; Peltz SW
The cap-to-tail guide to mRNA turnover
1005
23123 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(16):8991-8996
Rutter J; Michnoff CH; Harper SM; Gardner KH; McKnight SL
PAS kinase: An evolutionarily conserved PAS domain-regulated serine/threonine kinase
100
24324 2001 SCIENCE 293(5536):1832-1836
Kim VN; Kataoka N; Dreyfuss G
Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex
5831
25225 2001 SCIENCE 293(5536):1836-1839
Lykke-Andersen J; Shu MD; Steitz JA
Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1
660
26526 2001 TRENDS IN GENETICS 17(11):646-653
Mango SE
Stop making nonSense: the C-elegans smg genes
141
27127 2002 BIOCHIMIE 84(8):821-837
Tourriere H; Chebli K; Tazi J
mRNA degradation machines in eukaryotic cells
50
28228 2002 CELL 108(4):523-531
Reed R; Hurt E
A conserved rnRNA export machinery coupled to pre-mRNA splicing
662
29329 2002 CURRENT BIOLOGY 12(13):1060-1067
Dostie J; Dreyfuss G
Translation is required to remove Y14 from mRNAs in the cytoplasm
143
301030 2002 EMBO JOURNAL 21(13):3536-3545
Lejeune F; Ishigaki Y; Li XJ; Maquat LE
The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling
167
31231 2002 EMBO REPORTS 3(3):274-279
Wang J; Gudikote JP; Olivas OR; Wilkinson MF
Boundary-independent polar nonsense-mediated decay
72
32132 2002 GENE 298(2):121-127
Zhang KB; Dion N; Fuchs B; Damron T; Gitelis S; Irwin R; O'Connor M; Schwartz H; Scully SP; Rock MG; Bolander ME; Sarkar G
The human homolog of yeast SEP1 is a novel candidate tumor suppressor gene in osteogenic sarcoma
00
33133 2002 GENE EXPRESSION 10(1-2):79-92
Singh R
RNA-protein interactions that regulate pre-mRNA splicing
40
34534 2002 GENETICS 161(4):1465-1482
Shirley RL; Ford AS; Richards MR; Albertini M; Culbertson MR
Nuclear import of Upf3p is mediated by importin-alpha/-beta and export to the cytoplasm is required for a functional nonsense- mediated mRNA decay pathway in yeast
32
35135 2002 HORMONE RESEARCH 58(2):53-66
Mullis PE; Deladoey J; Dannies PS
Molecular and cellular basis of isolated dominant-negative growth hormone deficiency, IGHD type II: Insights on the secretory pathway of peptide hormones
10
36136 2002 HUMAN GENETICS 110(6):527-531
Ahmed ZM; Smith TN; Riazuddin S; Makishima T; Ghosh M; Bokhari S; Menon PSN; Deshmukh D; Griffith AJ; Riazuddin S; Friedman TB; Wilcox ER
Nonsyndromic recessive deafness DFNB18 and Usher syndrome type IC are allelic mutations of USHIC
70
37337 2002 HUMAN MOLECULAR GENETICS 11(3):331-335
Brocke KS; Neu-Yilik G; Gehring NH; Hentze MW; Kulozik AE
The human intronless melanocortin 4-receptor gene is NMD insensitive
82
38338 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(21):18489-18493
Wang J; Vock VM; Li SL; Olivas OR; Wilkinson MF
A quality control pathway that down-regulates aberrant T-cell receptor (TCR) transcripts by a mechanism requiring UPF2 and translation
104
39739 2002 JOURNAL OF CELL SCIENCE 115(15):3033-3038
Wagner E; Lykke-Andersen J
mRNA surveillance: the perfect persist
144
40440 2002 JOURNAL OF CLINICAL INVESTIGATION 109(1):3-6
Byers PH
Killing the messenger: new insights into nonsense-mediated mRNA decay
252
41341 2002 JOURNAL OF LIPID RESEARCH 43(11):1908-1919
Tarugi P; Ballarini G; Bembi B; Battisti C; Palmeri S; Panzani F; Di Leo E; Martini C; Federico A; Calandra S
Niemann-Pick type C disease: mutations of NPC1 gene and evidence of abnormal expression of some mutant alleles in fibroblasts
30
42142 2002 JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM 15():1301-1310
Mullis PE; Deladoey J; Dannies PS
New GH-1 gene mutations: Expanding the spectrum of causes of isolated growth hormone deficiency
00
43143 2002 METHODS 26(2):142-150
Coller J; Wickens M
Tethered function assays using 3 ' untranslated regions
00
44244 2002 MOLECULAR AND CELLULAR BIOLOGY 22(10):3301-3315
Cosson B; Couturier A; Chabelskaya S; Kiktev D; Inge-Vechtomov S; Philippe M; Zhouravleva G
Poly(A)-binding protein acts in translation termination via eukaryotic release factor 3 interaction and does not influence [PSI+] propagation
80
45945 2002 MOLECULAR AND CELLULAR BIOLOGY 22(23):8114-8121
Lykke-Andersen J
Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay
80
46246 2002 MOLECULES AND CELLS 14(3):323-331
Shim J; Karin M
The control of mRNA stability in response to extracellular stimuli
00
47447 2002 NATURE 416(6880):499-506
Maniatis T; Reed R
An extensive network of coupling among gene expression machines
1112
48448 2002 NATURE CELL BIOLOGY 4(6):E144-E147
Wilkinson MF; Bin Shyu A
RNA surveillance by nuclear scanning?
132
49149 2002 NATURE GENETICS 32(4):579-581
Ramoz N; Rueda LA; Bouadjar B; Montoya LS; Orth G; Favre M
Mutations in two adjacent novel genes are associated with epidermodysplasia verruciformis
30
50150 2002 NUCLEIC ACIDS RESEARCH 30(10):2232-2243
Carastro LM; Tan CK; Selg M; Jack HM; So AG; Downey KM
Identification of delta helicase as the bovine homolog of HUPF1: demonstration of an interaction with the third subunit of DNA polymerase delta
21
51251 2002 NUCLEIC ACIDS RESEARCH 30(11):2398-2406
Hashimoto Y; Zhang C; Kawauchi J; Imoto I; Adachi MT; Inazawa J; Amagasa T; Hai T; Kitajima S
An alternatively spliced isoform of transcriptional repressor ATF3 and its induction by stress stimuli
20
52152 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(20):12663-12668
Wang ZR; Jiao XF; Carr-Schmid A; Kiledjian M
The hDcp2 protein is a mammalian mRNA decapping enzyme
30
53653 2002 PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 72 72():129-164
Dodson RE; Shapiro DJ
Regulation of pathways of mRNA destabilization and stabilization
30
54154 2002 PROTEIN SENSORS AND REACTIVE OXYGEN SPECIES, PT A, SELENOPROTEINS AND THIOREDOXIN 347():49-57
Sun XL; Maquat LE
Nonsense-mediated decay: Assaying for effects on selenoprotein mRNAs
00
55355 2002 SCIENCE 298(5592):419-422
Mendell JT; Rhys CMJP; Dietz HC
Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts
168
56556 2003 BIOCHEMICAL JOURNAL 373():775-783
Schell T; Kocher T; Wilm M; Seraphin B; Kulozik AE; Hentze MW
Complexes between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cells
00
57157 2003 CANCER LETTERS 193(2):127-131
Hisatomi H; Tanemura H; Iizuka T; Katsumata K; Nagao K; Sumida H; Udagawa H; Hikiji K
Differential alternative splicing expressions of thymidylate synthase isoforms
00
58558 2003 CELLULAR AND MOLECULAR LIFE SCIENCES 60(4):639-647
McKendrick L
What's new in translation initiation? The first translation determines the fate of mRNA
00
59259 2003 CLINICAL AND EXPERIMENTAL IMMUNOLOGY 131(2):280-286
Baracho GV; Nudelman V; Isaac L
Molecular characterization of homozygous hereditary factor I deficiency
00
60260 2003 CURRENT GENETICS 43(3):171-177
Kebaara B; Nazarenus T; Taylor R; Atkin AL
Genetic background affects relative nonsense mRNA accumulation in wild-type and upf mutant yeast strains
00
61961 2003 CURRENT OPINION IN GENETICS & DEVELOPMENT 13(2):207-214
Culbertson MR; Leeds PF
Looking at mRNA decay pathways through the window of molecular evolution
00
62662 2003 EMBO JOURNAL 22(3):641-650
Anders KR; Grimson A; Anderson P
SMG-5, required for C-elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A
11
63263 2003 EMBO JOURNAL 22(15):3951-3959
Takahashi S; Araki Y; Sakuno T; Katada T
Interaction between Ski7p and Upf1p is required for nonsense- mediated 3 '-to-5 ' mRNA decay in yeast
00
64864 2003 EMBO JOURNAL 22(15):3960-3970
Gatfield D; Unterholzner L; Ciccarelli FD; Bork P; Izaurralde E
Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways
10
65265 2003 EMBO JOURNAL 22(15):3971-3982
Chester A; Somasekaram A; Tzimina M; Jarmuz A; Gisbourne J; O'Keefe R; Scott J; Navaratnam N
The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay
00
66266 2003 EMBO JOURNAL 22(20):5571-5581
Grskovic M; Hentze MW; Gebauer F
A co-repressor assembly nucleated by Sex-lethal in the 3 ' UTR mediates translational control of Drosophila msl-2 mRNA
00
67367 2003 GENES & DEVELOPMENT 17(4):461-475
Szymczyna BR; Bowman J; McCracken S; Pineda-Lucena A; Lu Y; Cox B; Lambermon M; Graveley BR; Arrowsmith CH; Blencowe BJ
Structure and function of the PWI motif: a novel nucleic acid- binding domain that facilitates pre-mRNA processing
00
68368 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(17):15291-15296
Yang TY; McNally BA; Ferrone S; Liu Y; Zheng P
A single-nucleotide deletion leads to rapid degradation of TAP- 1 mRNA in a melanoma cell line
10
69269 2003 JOURNAL OF MEDICAL GENETICS 40(5):360-363
Naz S; Alasti F; Mowjoodi A; Riazuddin S; Sanati MH; Friedman TB; Griffith AJ; Wilcox ER; Riazuddin S
Distinctive audiometric profile associated with DFNB21 alleles of TECTA
00
70270 2003 JOURNAL OF NEUROLOGY 250(5):581-587
Ito T; Takeshima Y; Yagi M; Kamei S; Wada H; Nakamura H; Matsuo M
Analysis of dystrophin mRNA from skeletal muscle but not from lymphocytes led to identification of a novel nonsense mutation in a carrier of Duchenne muscular dystrophy
00
71471 2003 MOLECULAR AND CELLULAR BIOLOGY 23(14):4805-4813
Chen CYA; Shyu AB
Rapid deadenylation triggered by a nonsense codon precedes decay of the RNA body in a mammalian cytoplasmic nonsense- mediated decay pathway
10
72872 2003 MOLECULAR CELL 11(4):939-949
Gehring NH; Neu-Yilik G; Schell T; Hentze MW; Kulozik AE
Y14 and hUpf3b form an NMD-activating complex
74
73473 2003 MOLECULAR CELL 12(1):5-14
Jurica MS; Moore MJ
Pre-mRNA splicing: Awash in a sea of proteins
10
74674 2003 MOLECULAR CELL 12(3):675-687
Lejeune F; Li XJ; Maquat LE
Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities
10
75275 2003 NUCLEIC ACIDS RESEARCH 31(12):3157-3165
Kebaara B; Nazarenus T; Taylor R; Forch A; Atkin AL
The Upf-dependent decay of wild-type PPR1 mRNA depends on its 5 '-UTR and first 92 ORF nucleotides
00
76576 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(1):189-192
Lewis BP; Green RE; Brenner SE
Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans
50
77977 2003 RNA-A PUBLICATION OF THE RNA SOCIETY 9(1):77-87
Chiu SY; Serin G; Ohara O; Maquat LE
Characterization of human Smg5/7a: A protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1
31
78978 2003 TRENDS IN BIOCHEMICAL SCIENCES 28(4):215-220
Le Hir H; Nott A; Moore MJ
How introns influence and enhance eukaryotic gene expression
40
79979 2003 TRENDS IN BIOCHEMICAL SCIENCES 28(9):464-466
Singh G; Lykke-Andersen J
New insights into the formation of active nonsensemediated decay complexes
00
80180 2003 YEAST 20(10):913-920
Runner VM; Brewster JL
A genetic screen for yeast genes induced by sustained osmotic stress
00

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