| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 1 | 0 | 1 2000 MOLECULAR CELL 6(6):1389-1399
Lindsten T; Ross AJ; King A; Zong WX; Rathmell JC; Shiels HA; Ulrich E; Waymire KG; Mahar P; Frauwirth K; Chen YF; Wei M; Eng VM; Adelman DM; Simon MC; Ma A; Golden JA; Evan G; Korsmeyer SJ; MacGregor GR; Thompson CB
The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues | 82 | 82
|
| 2 | 2 | 2 2001 BIOCHEMICAL SOCIETY TRANSACTIONS 29():684-688
Schuler M; Green DR
Mechanisms of p53-dependent apoptosis | 12 | 2
|
| 3 | 2 | 3 2001 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 1551(2):F1-F37
Zornig M; Hueber AO; Baum W; Evan G
Apoptosis regulators and their role in tumorigenesis | 18 | 0
|
| 4 | 5 | 4 2001 CELL AND TISSUE RESEARCH 306(3):347-361
Antonsson B
Bax and other pro-apoptotic Bcl-2 family "killer-proteins" and their victim, the mitochondrion | 10 | 0
|
| 5 | 2 | 5 2001 CELL DEATH AND DIFFERENTIATION 8(11):1066-1075
El-Deiry WS
Insights into cancer therapeutic design based on p53 and TRAIL receptor signaling | 4 | 0
|
| 6 | 2 | 6 2001 DEVELOPMENTAL BIOLOGY 239(2):295-308
Ross AJ; Amy SP; Mahar PL; Lindsten T; Knudson CM; Thompson CB; Korsmeyer SJ; MacGregor GR
BCLW mediates survival of postmitotic Sertoli cells by regulating BAX activity | 1 | 0
|
| 7 | 3 | 7 2001 DEVELOPMENTAL CELL 1(5):645-653
Bouillet P; Cory S; Zhang LC; Strasser A; Adams JM
Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist bim | 8 | 3
|
| 8 | 2 | 8 2001 EMBO JOURNAL 20(22):6306-6315
Makin GWJ; Corfe BM; Griffiths GJ; Thistlethwaite A; Hickman JA; Dive C
Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate | 5 | 2
|
| 9 | 2 | 9 2001 GENES & DEVELOPMENT 15(12):1481-1486
Zong WX; Lindsten T; Ross AJ; MacGregor GR; Thompson CB
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak | 61 | 23
|
| 10 | 6 | 10 2001 GENES & DEVELOPMENT 15(22):2922-2933
Wang XD
The expanding role of mitochondria in apoptosis | 62 | 6
|
| 11 | 1 | 11 2001 HIV-ASSOCIATED CARDIOVASCULAR DISEASE: CLINICAL AND BIOLOGICAL INSIGHTS 946():95-107
Szondy Z; Toth R; Szegezdi E; Reichert U; Ancian P; Fesus L
Cell death in HIV pathogenesis and its modulation by retinoids | 1 | 0
|
| 12 | 1 | 12 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(29):27432-27440
Zhao YG; Li SC; Childs EE; Kuharsky DK; Yin XM
Activation of pro-death Bcl-2 family proteins and mitochondria apoptosis pathway in tumor necrosis factor-alpha-induced liver injury | 8 | 1
|
| 13 | 2 | 13 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(36):34307-34317
Wang GQ; Gastman BR; Wieckowski E; Goldstein LA; Gambotto A; Kim TH; Fang BL; Rabinovitz A; Yin XM; Rabinowich H
A role for mitochondrial Bak in apoptotic response to anticancer drugs | 13 | 0
|
| 14 | 2 | 14 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(48):45120-45127
Sundararajan R; Cuconati A; Nelson D; White E
Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K | 9 | 3
|
| 15 | 1 | 15 2001 JOURNAL OF CELL BIOLOGY 153(6):1265-1276
Nechushtan A; Smith CL; Lamensdorf I; Yoon SH; Youle RJ
Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis | 31 | 5
|
| 16 | 1 | 16 2001 MOLECULAR AND CELLULAR BIOLOGY 21(22):7653-7662
Eischen CM; Roussel MF; Korsmeyer SJ; Cleveland JL
Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis | 5 | 1
|
| 17 | 1 | 17 2001 NATURE 412(6842):95-99
Li LY; Luo L; Wang XD
Endonuclease G is an apoptotic DNase when released from mitochondria | 110 | 9
|
| 18 | 2 | 18 2001 NATURE GENETICS 28(2):113-118
Ranger AM; Malynn BA; Korsmeyer SJ
Mouse models of cell death | 28 | 4
|
| 19 | 1 | 19 2001 NEUROSCIENCE 106(2):263-274
Honarpour N; Tabuchi K; Stark JM; Hammer RE; Sudhof TC; Parada LF; Wang X; Richardson JA; Herz J
Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of APAF-1 | 1 | 0
|
| 20 | 1 | 20 2001 ONCOGENE 20(40):5718-5725
Seidel MG; Look AT
E2A-HLF usurps control of evolutionarily conserved survival pathways | 0 | 0
|
| 21 | 1 | 21 2001 SCIENCE 292(5517):727-730
Wei MC; Zong WX; Cheng EHY; Lindsten T; Panoutsakopoulou V; Ross AJ; Roth KA; MacCregor GR; Thompson CB; Korsmeyer SJ
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death | 191 | 48
|
| 22 | 2 | 22 2001 SCIENTIST 15(13):1-+
Pray L
Life or death in cells | 0 | 0
|
| 23 | 1 | 23 2001 TRENDS IN CELL BIOLOGY 11(11):S22-S26
Makin G; Dive C
Apoptosis and cancer chemotherapy | 3 | 0
|
| 24 | 1 | 24 2001 TRENDS IN PHARMACOLOGICAL SCIENCES 22(6):306-315
Bratton SB; Cohen GM
Apoptotic death sensor: an organelle's alter ego? | 21 | 1
|
| 25 | 1 | 25 2002 ACTA PHYSIOLOGICA SCANDINAVICA 175(2):147-156
Westerlind KC; McCarty HL; Gibson KJ; Strange R
Effect of exercise on the rat mammary gland: implications for carcinogenesis | 0 | 0
|
| 26 | 2 | 26 2002 AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 282(4):L727-L734
Santore MT; McClintock DS; Lee VY; Budinger GRS; Chandel NS
Anoxia-induced apoptosis occurs through a mitochondria- dependent pathway in lung epithelial cells | 1 | 1
|
| 27 | 4 | 27 2002 ANNALS OF MEDICINE 34(6):451-469
Ding HF; Fisher DE
Induction of apoptosis in cancer: new therapeutic opportunities | 0 | 0
|
| 28 | 6 | 28 2002 APOPTOSIS 7(6):475-482
Brunelle JK; Chandel NS
Oxygen deprivation induced cell death: An update | 0 | 0
|
| 29 | 1 | 29 2002 ARCHIVES OF HISTOLOGY AND CYTOLOGY 65(4):291-300
Kuranaga E; Miura M
Molecular genetic control of caspases and JNK-mediated neural cell death | 0 | 0
|
| 30 | 2 | 30 2002 BIOCHIMIE 84(2-3):113-121
Waterhouse NJ; Ricci JE; Green DR
And all of a sudden it's over: mitochondrial outer-membrane permeabilization in apoptosis | 4 | 0
|
| 31 | 3 | 31 2002 BIOCHIMIE 84(2-3):187-193
Tsujimoto Y; Shimizu S
The voltage-dependent anion channel: an essential player in apoptosis | 1 | 0
|
| 32 | 1 | 32 2002 BIOCHIMIE 84(2-3):223-231
Chang LK; Putcha GV; Deshmukh M; Johnson EM
Mitochondrial involvement in the point of no return in neuronal apoptosis | 0 | 0
|
| 33 | 1 | 33 2002 BIOESSAYS 24(1):83-90
Corn PG; El-Deiry WS
Derangement of growth and differentiation control in oncogenesis | 1 | 0
|
| 34 | 2 | 34 2002 BIOLOGY OF REPRODUCTION 66(4):950-958
Russell LD; Chiarini-Garcia H; Korsmeyer SJ; Knudson CM
Bax-dependent spermatogonia apoptosis is required for testicular development and spermatogenesis | 1 | 0
|
| 35 | 3 | 35 2002 BIOSCIENCE REPORTS 22(1):47-58
Tsujimoto Y
Bcl-2 family of proteins: Life-or-death switch in mitochondria | 0 | 0
|
| 36 | 2 | 36 2002 BMC CANCER 2():art. no.-27
Mahyar-Roemer M; Kohler H; Roemer K
Role of Bax in resveratrol-induced apoptosis of colorectal carcinoma cells | 0 | 0
|
| 37 | 3 | 37 2002 CANCER CELL 1(1):19-30
Green DR; Evan GI
A matter of life and death | 16 | 3
|
| 38 | 9 | 38 2002 CANCER CELL 2(3):193-203
Degenhardt K; Chen GH; Lindsten T; White E
BAX and BAK mediate p53-independent suppression of tumorigenesis | 1 | 0
|
| 39 | 2 | 39 2002 CANCER RESEARCH 62(7):2184-2191
Eischen CM; Rehg JE; Korsmeyer SJ; Cleveland JL
Loss of Bax alters tumor spectrum and tumor numbers in ARF- deficient mice | 1 | 1
|
| 40 | 6 | 40 2002 CELL 109():S97-S107
Rathmell JC; Thompson CB
Pathways of apoptosis in lymphocyte development, homeostasis, and disease | 6 | 1
|
| 41 | 4 | 41 2002 CELL 111(3):331-342
Kuwana T; Mackey MR; Perkins G; Ellisman MH; Latterich M; Schneiter R; Green DR; Newmeyer DD
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane | 4 | 0
|
| 42 | 3 | 42 2002 CELL DEATH AND DIFFERENTIATION 9(3):301-308
Van Loo G; Demol H; van Gurp M; Hoorelbeke B; Schotte P; Beyaert R; Zhivotovsky B; Gevaert K; Declercq W; Vandekerckhove J; Vandenabeele P
A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid | 10 | 0
|
| 43 | 3 | 43 2002 CELL DEATH AND DIFFERENTIATION 9(5):505-512
Puthalakath H; Strasser A
Keeping killers on a tight leash: transcriptional and posttranslational control of the pro-apoptotic activity of BH3- only proteins | 4 | 1
|
| 44 | 2 | 44 2002 CIRCULATION JOURNAL 66(1):1-9
Kang PM; Yue P; Izumo S
New insights into the role of apoptosis in cardiovascular disease | 0 | 0
|
| 45 | 2 | 45 2002 CURRENT OPINION IN HEMATOLOGY 9(1):43-49
Pinkoski MJ; Green DR
Lymphocyte apoptosis: refining the paths to perdition | 1 | 0
|
| 46 | 2 | 46 2002 CURRENT OPINION IN IMMUNOLOGY 14(3):354-359
Hildeman DA; Zhu YN; Mitchell TC; Kappler J; Marrack P
Molecular mechanisms of activated T cell death in vivo | 2 | 0
|
| 47 | 1 | 47 2002 CURRENT OPINION IN ONCOLOGY 14(1):86-91
Bargonetti J; Manfredi JJ
Multiple roles of the tumor suppressor p53 | 15 | 0
|
| 48 | 5 | 48 2002 CURRENT OPINION IN ONCOLOGY 14(5):490-503
Ravi R; Bedi A
Potential methods to circumvent blocks in apoptosis in lymphomas | 0 | 0
|
| 49 | 1 | 49 2002 DEVELOPMENTAL BIOLOGY 243(1):185-206
Chiao E; Fisher P; Crisponi L; Deiana M; Dragatsis I; Schlessinger D; Pilia G; Efstratiadis A
Overgrowth of a mouse model of the Simpson-Golabi-Behmel syndrome is independent of IGF signaling | 2 | 0
|
| 50 | 1 | 50 2002 DEVELOPMENTAL BIOLOGY 249(1):108-120
Guha U; Gomes WA; Kobayashi T; Pestell RG; Kessler JA
In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb | 0 | 0
|
| 51 | 6 | 51 2002 GENES & DEVELOPMENT 16(19):2465-2478
Cuconati A; White E
Viral homologs of BCL-2: role of apoptosis in the regulation of virus infection | 0 | 0
|
| 52 | 1 | 52 2002 HEMATOLOGICAL ONCOLOGY 20(2):63-74
Baliga BC; Kumar S
Role of Bcl-2 family of proteins in malignancy | 0 | 0
|
| 53 | 3 | 53 2002 IMMUNITY 17(5):561-573
Khaled AR; Li WQ; Huang JQ; Fry TJ; Khaled AS; Mackall CL; Muegge K; Young HA; Durum SK
Bax deficiency partially corrects interleukin-7 receptor alpha deficiency | 0 | 0
|
| 54 | 1 | 54 2002 INFLAMMATORY BOWEL DISEASES 8(1):35-42
Boone DL; Dassopoulos T; Lodolce JP; Chai S; Chien M; Ma A
Interleukin-2-deficient mice develop colitis in the absence of CD28 costimulation | 0 | 0
|
| 55 | 2 | 55 2002 INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY 46(7):871-876
Zuzarte-Luis V; Hurle JM
Programmed cell death in the developing limb | 0 | 0
|
| 56 | 2 | 56 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(6):4351-4360
Stegh AH; Barnhart BC; Volkland J; Algeciras-Schimnich A; Ke N; Reed JC; Peter ME
Inactivation of caspase-8 on mitochondria of Bcl-x(L)- expressing MCF7-Fas cells - Role for the bifunctional apoptosis regulator protein | 2 | 0
|
| 57 | 3 | 57 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(16):14040-14047
Tsuruta F; Masuyama N; Gotoh Y
The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria | 1 | 0
|
| 58 | 4 | 58 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(16):14127-14134
Degenhardt K; Sundararajan R; Lindsten T; Thompson C; White E
Bax and Bak independently promote cytochrome c release from mitochondria | 3 | 2
|
| 59 | 3 | 59 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(18):15654-15660
Budinger GRS; Tso M; McClintock DS; Dean DA; Sznajder JI; Chandel NS
Hyperoxia-induced apoptosis does not require mitochondrial reactive oxygen species and is regulated by Bcl-2 proteins | 0 | 0
|
| 60 | 9 | 60 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(44):41604-41612
Yamaguchi H; Wang HG
Bcl-XL protects BimEL-induced Bax conformational change and cytochrome c release independent of interacting with Bax or BimEL | 0 | 0
|
| 61 | 3 | 61 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(47):44870-44876
Vander Heiden MG; Choy JS; VanderWeele DJ; Brace JL; Harris MH; Bauer DE; Prange B; Kron SJ; Thompson CB; Rudin CM
Bcl-x(L) complements Saccharomyces cerevisiae genes that facilitate the switch from glycolytic to oxidative metabolism | 0 | 0
|
| 62 | 3 | 62 2002 JOURNAL OF CELL BIOLOGY 157(3):441-453
Putcha GV; Harris CA; Moulder KL; Easton RM; Thompson CB; Johnson EM
Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice | 2 | 0
|
| 63 | 5 | 63 2002 JOURNAL OF CELL SCIENCE 115(8):1567-1574
Bouillet P; Strasser A
BH3-only proteins - evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death | 2 | 0
|
| 64 | 2 | 64 2002 JOURNAL OF CELL SCIENCE 115(24):4727-4734
Cande C; Cecconi F; Dessen P; Kroemer G
Apoptosis-inducing factor (AIF): key to the conserved caspase- independent pathways of cell death? | 1 | 0
|
| 65 | 1 | 65 2002 JOURNAL OF IMMUNOLOGICAL METHODS 265(1-2):3-20
Zakeri Z; Lockshin RA
Cell death during development | 0 | 0
|
| 66 | 4 | 66 2002 JOURNAL OF IMMUNOLOGY 168(8):3902-3909
Herold MJ; Kuss AW; Kraus C; Berberich I
Mitochondria-dependent caspase-9 activation is necessary for antigen receptor-mediated effector caspase activation and apoptosis in WEHI 231 lymphoma cells | 1 | 1
|
| 67 | 1 | 67 2002 JOURNAL OF NEUROSCIENCE RESEARCH 69(6):803-809
Israsena N; Kessler JA
Msx2 and p21(C1P1/WAF1) mediate the proapoptotic effects of bone morphogenetic protein-4 on ventricular zone progenitor cells | 1 | 0
|
| 68 | 1 | 68 2002 MECHANISMS OF DEVELOPMENT 113(2):111-120
Dunker N; Schmitt K; Krieglstein K
TGF-beta is required for programmed cell death in interdigital webs of the developing mouse limb | 1 | 1
|
| 69 | 2 | 69 2002 MOLECULAR AND CELLULAR BIOLOGY 22(1):94-104
McClintock DS; Santore MT; Lee VY; Brunelle J; Budinger GRS; Zong WX; Thompson CB; Hay N; Chandel NS
Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death | 8 | 2
|
| 70 | 2 | 70 2002 MOLECULAR AND CELLULAR BIOLOGY 22(1):207-220
Algeciras-Schimnich A; Shen L; Barnhart BC; Murmann AE; Burkhardt JK; Peter ME
Molecular ordering of the initial signaling events of CD95 | 10 | 0
|
| 71 | 4 | 71 2002 MOLECULAR AND CELLULAR BIOLOGY 22(13):4929-4942
Lei K; Nimnual A; Zong WX; Kennedy NJ; Flavell RA; Thompson CB; Bar-Sagi D; Davis RJ
The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH2-terminal kinase | 2 | 0
|
| 72 | 3 | 72 2002 MOLECULAR AND CELLULAR BIOLOGY 22(17):6158-6169
Juin P; Hunt A; Littlewood T; Griffiths B; Swigart LB; Korsmeyer S; Evan G
c-Myc functionally cooperates with Bax to induce apoptosis | 0 | 0
|
| 73 | 1 | 73 2002 MOLECULAR AND CELLULAR BIOLOGY 22(18):6521-6532
Hirao A; Cheung A; Duncan G; Girard PM; Elia AJ; Wakeham A; Okada H; Sarkissian T; Wong JA; Sakai T; de Stanchina E; Bristow RG; Suda T; Lowe SW; Jeggo PA; Elledge SJ; Mak TW
Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM- independent manner | 2 | 0
|
| 74 | 3 | 74 2002 NATURE IMMUNOLOGY 3(10):893-894
Bouillet P; Strasser A
Bax and Bak: back-bone of T cell death | 0 | 0
|
| 75 | 3 | 75 2002 NATURE IMMUNOLOGY 3(10):932-939
Rathmell JC; Lindsten T; Zong WX; Cinalli RM; Thompson CB
Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis | 1 | 1
|
| 76 | 2 | 76 2002 NATURE MEDICINE 8(3):274-281
LeBlanc H; Lawrence D; Varfolomeev E; Totpal K; Morlan J; Schow P; Fong S; Schwall R; Sinicropi D; Ashkenazi A
Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax | 16 | 2
|
| 77 | 1 | 77 2002 NEOPLASIA 4(6):551-557
Ozoren N; El-Deiry WS
Defining characteristics of Types I and II apoptotic cells in response to TRAIL | 0 | 0
|
| 78 | 2 | 78 2002 ONCOGENE 21(7):990-999
Thornborrow EC; Patel S; Mastropietro AE; Schwartzfarb EM; Manfredi JJ
A conserved intronic response element mediates direct p53- dependent transcriptional activation of both the human and murine bax genes | 5 | 0
|
| 79 | 3 | 79 2002 ONCOGENE 21(16):2534-2544
Mathai JP; Germain M; Marcellus RC; Shore GC
Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53 | 1 | 0
|
| 80 | 2 | 80 2002 ONCOGENE 21(21):3284-3294
Lotem J; Sachs L
Cytokine control of developmental programs in normal hematopoiesis and leukemia | 0 | 0
|
| 81 | 1 | 81 2002 TERATOLOGY 66(6):288-299
Huang CW; Hales BF
Role of Caspases in murine limb bud cell death induced by 4- hydroperoxycyclophosphamide, an activated analog of cyclophosphamide | 0 | 0
|
| 82 | 4 | 82 2002 TRENDS IN ENDOCRINOLOGY AND METABOLISM 13(2):74-78
Plas DR; Thompson CB
Cell metabolism in the regulation of programmed cell death | 1 | 0
|
| 83 | 3 | 83 2002 TRENDS IN GENETICS 18(3):142-149
Joza N; Kroemer G; Penninger JM
Genetic analysis of the mammalian cell death machinery | 3 | 0
|