Nodes: 148, Authors: 520, Sources: 76, Outer References: 3733
Collection span: 2002 - 2004
View: Overview. Sorted by year, source, volume, issue, page.

#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
1	2	69	1 2002 AIDS 16():S17-S23 Gummuluru S; Emerman M Advances in HIV molecular biology	0	0
2	4	99	2 2002 AIDS 16():S25-S31 Ameisen JC; Lelievre JD; Pleskoff O HIV/host interactions: new lessons from the Red Queen's country	0	0
3	1	28	3 2002 AIDS 16(18):2385-2390 Martinez MA; Gutierrez A; Armand-Ugon M; Blanco J; Parera M; Gomez J; Clotet B; Este JA Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication	14	19
4	2	51	4 2002 ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT 12(5):301-309 Hamada M; Ohtsuka T; Kawaida R; Koizumi M; Morita K; Furukawa H; Imanishi T; Miyagishi M; Taira K Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3 '-ends of siRNAs	4	8
5	1	14	5 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 295(3):744-748 Leirdal M; Sioud M Gene silencing in mammalian cells by preformed small RNA duplexes	5	7
6	2	68	6 2002 BIOLOGICAL CHEMISTRY 383(10):1483-1489 Metzlaff M RNA-mediated RNA degradation in transgene-and virus-induced gene silencing	0	0
7	1	70	7 2002 CANCER CELL 2(1):17-23 Paddison PJ; Hannon GJ RNA interference: the new somatic cell genetics?	12	35
8	4	52	8 2002 CURRENT OPINION IN CHEMICAL BIOLOGY 6(6):829-834 Agami R RNAi and related mechanisms and their potential use for therapy	3	9
9	1	52	9 2002 CURRENT OPINION IN PHARMACOLOGY 2(5):541-547 Tang HL; Peng T; Wong-Staal F Novel technologies for studying virus-host interaction and discovering new drug targets for HCV and HIV	0	1
10	1	49	10 2002 DRUG DISCOVERY TODAY 7(17):912-917 Thompson JD Applications of antisense and siRNAs during preclinical drug development	1	5
#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
11	2	72	11 2002 DRUG DISCOVERY TODAY 7(19):1013-1019 van Huijsduijnen RH; Bombrun A; Swinnen D Selecting protein tyrosine phosphatases as drug targets	0	13
12	1	53	12 2002 DRUG DISCOVERY TODAY 7(20):1040-1046 Shuey DJ; McCallus DE; Giordano T RNAi: gene-silencing in therapeutic intervention	2	11
13	1	20	13 2002 FEBS LETTERS 532(1-2):227-230 Hasuwa H; Kaseda K; Einarsdottir T; Okabe M Small interfering RNA and gene silencing in transgenic mice and rats	9	24
14	1	27	14 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(48):46442-46446 Gaudilliere B; Shi Y; Bonni A RNA interference reveals a requirement for myocyte enhancer factor 2A in activity-dependent neuronal survival	1	9
15	1	23	15 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(49):46849-46851 Rajagopal R; Sivakumar S; Agrawal N; Malhotra P; Bhatnagar RK Silencing of midgut aminopeptidase N of Spodoptera litura by double-stranded RNA establishes its role as bacillus thuringiensis toxin receptor	0	4
16	1	27	16 2002 JOURNAL OF IMMUNOLOGY 169(9):5196-5201 Capodici J; Kariko K; Weissman D Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference	16	23
17	2	91	17 2002 JOURNAL OF VIROLOGY 76(24):12963-12973 Surabhi RM; Gaynor RB RNA interference directed against viral and cellular targets inhibits human immunodeficiency virus type 1 replication	10	17
18	2	30	18 2002 MICROBIOLOGY AND IMMUNOLOGY 46(11):809-817 Yamamoto T; Omoto S; Mizuguchi M; Mizukami H; Okuyama H; Okada N; Saksena NK; Brisibe EA; Otake K; Fujii YR Double-stranded nef RNA interferes with human immunodeficiency virus type 1 replication	7	8
19	1	56	19 2002 MOLECULAR THERAPY 6(6):770-782 Bai JR; Banda N; Lee NS; Rossi J; Akkina R RNA-based anti-HIV-1 gene therapeutic constructs in SCID-hu mouse model	2	3
20	1	77	20 2002 NATURE 418(6894):252-258 Sullenger BA; Gilboa E Emerging clinical applications of RNA	5	42
#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
21	2	15	21 2002 NATURE 418(6896):379-380 Carmichael GG Medicine - Silencing viruses with RNA	2	10
22	1	11	22 2002 NATURE BIOTECHNOLOGY 20(5):446-448 Tuschl T Expanding small RNA interference	23	64
23	0	19	23 2002 NATURE BIOTECHNOLOGY 20(5):500-505 Lee NS; Dohjima T; Bauer G; Li HT; Li MJ; Ehsani A; Salvaterra P; Rossi J Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells	147	147
24	1	32	24 2002 NATURE BIOTECHNOLOGY 20(10):1006-1010 Xia HB; Mao QW; Paulson HL; Davidson BL siRNA-mediated gene silencing in vitro and in vivo	22	78
25	1	18	25 2002 NATURE MEDICINE 8(7):659-660 Pomerantz RJ RNA interference meets HIV-1: Will silence be golden?	6	10
26	1	45	26 2002 NATURE MEDICINE 8(7):681-686 Novina CD; Murray MF; Dykxhoorn DM; Beresford PJ; Riess J; Lee SK; Collman RG; Lieberman J; Shankar P; Sharp PA siRNA-directed inhibition of HIV-1 infection	62	110
27	2	125	27 2002 NATURE REVIEWS DRUG DISCOVERY 1(11):867-881 Tan SL; Pause A; Shi YU; Sonenberg N Hepatitis C therapeutics: Current status and emerging strategies	0	11
28	3	107	28 2002 NATURE REVIEWS GENETICS 3(10):737-747 McManus MT; Sharp PA Gene silencing in mammals by small interfering RNAs	23	129
29	1	2	29 2002 NATURE REVIEWS IMMUNOLOGY 2(7):458-459 Buckland J Silencing HIV-1	0	0
30	3	25	30 2002 NEW ENGLAND JOURNAL OF MEDICINE 347(17):1364-1367 Kitabwalla M; Ruprecht RM RNA interference - A new weapon against HIV and beyond	5	14
#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
31	1	36	31 2002 NUCLEIC ACIDS RESEARCH 30(22):4830-4835 Park WS; Miyano-Kurosaki N; Hayafune M; Nakajima E; Matsuzaki T; Shimada F; Takaku H Prevention of HIV-1 infection in human peripheral blood mononuclear cells by specific RNA interference	8	11
32	1	22	32 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(18):11926-11929 Krichevsky AM; Kosik KS RNAi functions in cultured mammalian neurons	6	30
33	2	15	33 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(23):14943-14945 Barton GM; Medzhitov R Retroviral delivery of small interfering RNA into primary cells	20	39
34	1	39	34 2002 RNA-A PUBLICATION OF THE RNA SOCIETY 8(6):842-850 McManus MT; Petersen CP; Haines BB; Chen JZ; Sharp PA Gene silencing using micro-RNA designed hairpins	23	39
35	2	14	35 2002 RNA-A PUBLICATION OF THE RNA SOCIETY 8(11):1454-1460 Castanotto D; Li HT; Rossi JJ Functional siRNA expression from transfected PCR products	3	7
36	3	36	36 2002 TRENDS IN BIOTECHNOLOGY 20(11):462-466 Famulok M; Verma S In vivo-applied functional RNAs as tools in proteomics and genomics research	1	7
37	1	17	37 2002 TRENDS IN CELL BIOLOGY 12(10):485-488 Wu RZ; Bailey SN; Sabatini DM Cell-biological applications of transfected-cell microarrays	0	5
38	2	29	38 2002 TRENDS IN IMMUNOLOGY 23(12):559-561 Martinez MA; Clotet B; Este JA RNA interference of HIV replication	4	7
39	3	19	39 2002 TRENDS IN MOLECULAR MEDICINE 8(11):505-508 Silva JM; Hammond SM; Hannon GJ RNA interference: a promising approach to antiviral therapy?	2	3
40	1	21	40 2003 ACTA BIOCHIMICA ET BIOPHYSICA SINICA 35(3):238-246 Meng GL; Tang FC; Zhang JZ; Zhao WN; Shang KG; Ding MX; Xue YF RNA interference in three ES cell lines from different mouse strains	1	1
#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
41	4	42	41 2003 AGING CELL 2(4):209-217 Ding HL; Schwarz DS; Keene A; Affar EB; Fenton L; Xia XA; Shi Y; Zamore PD; Xu ZS Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis	1	2
42	5	30	42 2003 AIDS RESEARCH AND HUMAN RETROVIRUSES 19(8):699-706 Anderson J; Banerjea A; Planelles V; Akkina R Potent suppression of HIV type 1 infection by a short hairpin anti-CXCR4 siRNA	0	0
43	1	28	43 2003 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 42(21):2424-2427 Welz R; Bossmann K; Klug C; Schmidt C; Fritz HJ; Muller S Site-directed alteration of RNA sequence mediated by an engineered twin ribozyme	0	2
44	4	38	44 2003 ANTICANCER RESEARCH 23(3A):1997-2005 Akkina R; Banerjea A; Bai JR; Anderson J; Li MJ; Rossi J siRNAs, ribozymes and RNA decoys in modeling stem cell-based gene therapy for HIV/AIDS	0	0
45	9	110	45 2003 ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT 13(2):83-105 Harborth J; Elbashir SM; Vandenburgh K; Manninga H; Scaringe SA; Weber K; Tuschl T Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing	1	3
46	9	55	46 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 303(4):1169-1178 Zhang L; Yang N; Mohamed-Hadley A; Rubin SC; Coukos G Vector-based RNAi, a novel tool for isoform-specific knock-down of VEGF and anti-angiogenesis gene therapy of cancer	3	8
47	8	36	47 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 305(3):548-551 Tilly G; Chapuis J; Vilette D; Laude H; Vilotte JL Efficient and specific down-regulation of prion protein expression by RNAi	0	1
48	1	23	48 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 306(3):712-717 Xu YH; Zhang HY; Thormeyer D; Larsson A; Du Q; Elmen J; Wahlestedt C; Liang Z Effective small interfering RNAs and phosphorothioate antisense DNAs have different preferences for target sites in the luciferase mRNAs	0	0
49	7	29	49 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 311(2):398-404 Chen Y; Du D; Wu J; Chan CP; Tan YQ; Kung HF; He ML Inhibition of hepatitis B virus replication by stably expressed shRNA	0	1
50	1	36	50 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 311(4):1057-1066 Xu ZH; Liang L; Wang HF; Li TP; Zhao MJ HCRP1, a novel gene that is downregulated in hepatocellular carcinoma, encodes a growth-inhibitory protein	0	0
#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
51	3	146	51 2003 BIOCHEMISTRY-MOSCOW 68(10):1063-1076 Kuznetsov VV RNA interference. An approach to produce knockout organisms and cell lines	0	0
52	3	12	52 2003 BIOTECHNIQUES 34(6):1140-+ Ducat DC; Herrera FJ; Triezenberg SJ Overcoming obstacles in DNA sequencing of expression plasmids for short interfering RNAs	0	0
53	2	25	53 2003 BLOOD 101(4):1566-1569 Scherr M; Battmer K; Winkler T; Heidenreich O; Ganser A; Eder M Specific inhibition of bcr-abl gene expression by small interfering RNA	6	13
54	3	35	54 2003 CANCER BIOLOGY & THERAPY 2(2):206-210 Matta H; Hozayev B; Tomar R; Chugh P; Chaudhary PM Use of lentiviral vectors for delivery of small interfering RNA	1	1
55	2	33	55 2003 CANCER RESEARCH 63(7):1515-1519 Wu H; Hait WN; Yang JM Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells	2	6
56	5	20	56 2003 CANCER RESEARCH 63(16):4801-4804 Chen YC; Stamatoyannopoulos G; Song CZ Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro	1	3
57	5	45	57 2003 CANCER RESEARCH 63(20):6809-6814 Oshima K; Kawasaki H; Soda Y; Tani K; Asano S; Taira K Maxizymes and small hairpin-type RNAs that are driven by a tRNA promoter specifically cleave a chimeric gene associated with leukemia in vitro and in vivo	0	0
58	10	59	58 2003 CHEMBIOCHEM 4(11):1129-1136 Arendt CW; Tang GL; Zilberstein A Vector systems for the delivery of small interfering RNAs: Managing the RISC	0	0
59	3	91	59 2003 CURRENT MEDICINAL CHEMISTRY 10(3):245-256 Scherr M; Morgan MA; Eder M Gene silencing mediated by small interfering RNAs in mammalian cells	1	10
60	3	55	60 2003 CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION 12(4):415-421 Jarad G; Simske JS; Sedor JR; Schelling JR Nucleic acid-based techniques for post-transcriptional regulation of molecular targets	1	1
#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
61	2	43	61 2003 CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION 12(4):439-445 Hanss B; Bruggeman LA Applications of gene therapy to kidney disease	0	0
62	4	35	62 2003 DEVELOPMENT GROWTH & DIFFERENTIATION 45(4):361-367 Katahira T; Nakamura H Gene silencing in chick embryos with a vector-based small interfering RNA system	0	0
63	2	78	63 2003 DEVELOPMENTAL DYNAMICS 226(2):202-210 Poss KD; Keating MT; Nechiporuk A Tales of regeneration in zebrafish	0	3
64	1	62	64 2003 DNA REPAIR 2(5):581-591 Rosenquist TA; Zaika E; Fernandes AS; Zharkov DO; Miller H; Grollman AP The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation-mediated cell death	0	5
65	1	53	65 2003 ELECTRONIC JOURNAL OF BIOTECHNOLOGY 6(1):39-49 Thakur A RNA interference revolution	0	0
66	6	131	66 2003 EUROPEAN JOURNAL OF BIOCHEMISTRY 270(8):1628-1644 Kurreck J Antisense technologies - Improvement through novel chemical modifications	0	12
67	5	60	67 2003 EXPERT OPINION ON BIOLOGICAL THERAPY 3(3):459-467 Milner J RNA interference for treating cancers caused by viral infection	0	0
68	24	168	68 2003 EXPERT OPINION ON BIOLOGICAL THERAPY 3(4):575-586 Caplen NJ RNAi as a gene therapy approach	0	2
69	7	117	69 2003 EXPERT OPINION ON BIOLOGICAL THERAPY 3(6):951-963 Poluri A; van Maanen M; Sutton RE Genetic therapy for HIV/AIDS	0	1
70	6	21	70 2003 FEBS LETTERS 552(2-3):247-252 Ji JM; Wernli M; Klimkait T; Erb P Enhanced gene silencing by the application of multiple specific small interfering RNAs	0	1
#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
71	2	13	71 2003 GENE 316():137-141 Zhao LJ; Jian H; Zhu HH Specific gene inhibition by adenovirus-mediated expression of small interfering RNA	0	0
72	2	20	72 2003 GENE THERAPY 10(24):2046-2050 Park WS; Hayafune M; Miyano-Kurosaki N; Takaku H Specific HIV-1 env gene silencing by small interfering RNAs in human peripheral blood mononuclear cells	0	0
73	4	30	73 2003 GENOME RESEARCH 13(10):2325-2332 Arts GJ; Langemeijer E; Tissingh R; Ma LB; Pavliska H; Dokic K; Dooijes R; Misic E; Clasen R; Michiels F; van der Schueren J; Lambrecht M; Herman S; Brys R; Thys K; Hoffmann M; Tomme P; van Es H Adenoviral vectors expressing siRNAs for discovery and validation of gene function	0	0
74	5	37	74 2003 GENOME RESEARCH 13(10):2333-2340 Kumar R; Conklin DS; Mittal V High-throughput selection of effective RNAi probes for gene silencing	0	1
75	1	109	75 2003 GUT 52():40-47 Tavitian B In vivo imaging with oligonucleotides for diagnosis and drug development	0	0
76	1	27	76 2003 HEPATOLOGY 37(4):764-770 Shlomai A; Shaul Y Inhibition of hepatitis B virus expression and replication by RNA interference	5	10
77	6	41	77 2003 HEPATOLOGY 38(4):842-850 Konishi M; Wu CH; Wu GY Inhibition of HBV replication by siRNA in a stable HBV-producing cell line	0	0
78	4	34	78 2003 HUMAN GENE THERAPY 14(12):1207-1212 An DS; Xie YM; Mao SH; Morizono K; Kung SKP; Chen ISY Efficient lentiviral vectors for short hairpin RNA delivery into human cells	0	1
79	4	28	79 2003 HUMAN MOLECULAR GENETICS 12(20):2637-2644 Abdelgany A; Wood M; Beeson D Allele-specific silencing of a pathogenic mutant acetylcholine receptor subunit by RNA interference	0	0
80	4	187	80 2003 IMMUNOLOGY AND CELL BIOLOGY 81(3):196-206 Diamond MS Evasion of innate and adaptive immunity by flaviviruses	0	2
#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
81	1	37	81 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(3):1433-1442 Bai JR; Sui JH; Zhu RY; Tallarico AS; Gennari F; Zhang DS; Marasco WA Inhibition of Tat-mediated transactivation and HIV-1 replication by human anti-hCyclinT1 intrabodies	1	7
82	1	27	82 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(18):15991-15997 Bohula EA; Salisbury AJ; Sohail M; Playford MP; Riedemann J; Southern EM; Macaulay VM The efficacy of small interfering RNAs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF1R transcript	3	13
83	2	66	83 2003 JOURNAL OF BIOMEDICAL SCIENCE 10(5):457-467 Khan AU; Lal SK Ribozymes: A modern tool in medicine	0	0
84	14	72	84 2003 JOURNAL OF BIOMEDICAL SCIENCE 10(6):607-616 Haasnoot J; Cupac D; Berkhout B Inhibition of virus replication by RNA interference	0	0
85	23	114	85 2003 JOURNAL OF KOREAN MEDICAL SCIENCE 18(3):309-318 Kim VN RNA interference in functional genomics and medicine	0	0
86	2	28	86 2003 JOURNAL OF MOLECULAR BIOLOGY 327(4):761-766 Sorensen DR; Leirdal M; Sioud M Gene silencing by systemic delivery of synthetic siRNAs in adult mice	2	9
87	2	15	87 2003 JOURNAL OF VIROLOGY 77(1):810-812 Seo MY; Abrignani S; Houghton M; Han JH Small interfering RNA-mediated inhibition of hepatitis C virus replication in the human hepatoma cell line Huh-7	5	11
88	2	42	88 2003 JOURNAL OF VIROLOGY 77(5):3301-3306 Jia QM; Sun R Inhibition of gammaherpesvirus replication by RNA interference	6	9
89	9	73	89 2003 JOURNAL OF VIROLOGY 77(13):7159-7165 Gitlin L; Andino R Nucleic acid-based immune system: the antiviral potential of mammalian RNA silencing	0	1
90	10	36	90 2003 JOURNAL OF VIROLOGY 77(13):7174-7181 Song EW; Lee SK; Dykxhoorn DM; Novina C; Zhang D; Crawford K; Cerny J; Sharp PA; Lieberman J; Manjunath N; Shankar P Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages	2	4
#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
91	4	25	91 2003 JOURNAL OF VIROLOGY 77(17):9728-9731 Chang J; Taylor JM Susceptibility of human hepatitis delta virus RNAs to small interfering RNA action	0	0
92	3	32	92 2003 JOURNAL OF VIROLOGY 77(18):9817-9822 Guo F; Cen S; Niu MJ; Javanbakht H; Kleiman L Specific inhibition of the synthesis of human lysyl-tRNA synthetase results in decreases in tRNA(Lys) incorporation, tRNA(3)(Lys) annealing to viral RNA, and viral infectivity in human immunodeficiency virus type 1	0	1
93	6	11	93 2003 JOURNAL OF VIROLOGY 77(21):11531-11535 Boden D; Pusch O; Lee F; Tucker L; Ramratnam B Human immunodeficiency virus type 1 escape from RNA interference	1	1
94	10	51	94 2003 JOURNAL OF VIROLOGY 77(22):11964-11972 Lee MTM; Coburn GA; McClure MO; Cullen BR Inhibition of human immunodeficiency virus type 1 replication in primary macrophages by using Tat-or CCR5-specific small interfering RNAs expressed from a lentivirus vector	0	0
95	3	77	95 2003 MOLECULAR AND CELLULAR BIOLOGY 23(13):4417-4427 Vojtek AB; Taylor J; DeRuiter SL; Yu JY; Figueroa C; Kwok RPS; Turner DL Akt regulates basic helix-loop-helix transcription factor-coactivator complex formation and activity during neuronal differentiation	0	1
96	10	89	96 2003 MOLECULAR GENETICS AND METABOLISM 80(1-2):121-128 Cheng JC; Moore TB; Sakamoto KM RNA interference and human disease	0	0
97	2	47	97 2003 MOLECULAR THERAPY 7(2):228-236 Yu JY; Taylor J; DeRuiter SL; Vojtek AB; Turner DL Simultaneous inhibition of GSK3 alpha and GSK3 beta using hairpin siRNA expression vectors	2	9
98	2	51	98 2003 MOLECULAR THERAPY 7(2):237-247 Paul CP; Good PD; Li SXL; Kleihauer A; Rossi JJ; Engelke DR Localized expression of small RNA inhibitors in human cells	0	0
99	4	32	99 2003 MOLECULAR THERAPY 7(6):811-816 Dohjima T; Lee NS; Li HT; Ohno T; Rossi JJ Small interfering RNAs expressed from a pol III promoter suppress the EWS/Fli-1 transcript in an Ewing sarcoma cell line	0	0
100	2	29	100 2003 MOLECULAR THERAPY 7(6):817-826 Chakraborti S; Banerjea AC Inhibition of HIV-1 gene expression by novel DNA enzymes targeted to cleave HIV-1 TAR RNA: Potential effectiveness against all HIV-1 isolates	0	0
#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
101	7	45	101 2003 MOLECULAR THERAPY 8(1):62-71 Banerjea A; Li MJ; Bauer G; Remling L; Lee NS; Rossi J; Akkina R Inhibition of HIV-1 by lentiviral vector-transduced siRNAs in T lymphocytes differentiated in SCID-hu mice and CD34(+) progenitor cell-derived macrophages	1	3
102	10	73	102 2003 MOLECULAR THERAPY 8(2):196-206 Li MJ; Bauer G; Michienzi A; Yee JK; Lee NS; Kim J; Li S; Castanotto D; Zaia J; Rossi JJ Inhibition of HIV-1 infection by lentiviral vectors expressing pol III-promoted anti-HIV RNAs	0	0
103	4	8	103 2003 NATURE BIOTECHNOLOGY 21(3):230-231 Arteaga HJ; Hinkula J; van Dijk-Hard I; Dilber MS; Wahren B; Christensson B; Mohamed AJ; Smith CIE Choosing CCR5 or Rev siRNA in HIV-1	2	5
104	2	20	104 2003 NATURE BIOTECHNOLOGY 21(3):324-328 Myers JW; Jones JT; Meyer T; Ferrell JE Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing	3	9
105	3	17	105 2003 NATURE BIOTECHNOLOGY 21(5):559-561 Kunath T; Gish G; Lickert H; Jones N; Pawson T; Rossant J Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype	3	12
106	4	24	106 2003 NATURE BIOTECHNOLOGY 21(6):639-644 McCaffrey AP; Nakai H; Pandey K; Huang Z; Salazar FH; Xu H; Wieland SF; Marion PL; Kay MA Inhibition of hepatitis B virus in mice by RNA interference	5	15
107	5	28	107 2003 NATURE GENETICS 33(3):401-406 Rubinson DA; Dillon CP; Kwiatkowski AV; Sievers C; Yang LL; Kopinja J; Zhang MD; McManus MT; Gertler FB; Scott ML; Van Parijs L A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference	19	49
108	5	73	108 2003 NATURE REVIEWS CANCER 3(10):781-789 Brummelkamp TR; Bernards R Innovation - New tools for functional mammalian cancer genetics	0	0
109	2	132	109 2003 NATURE REVIEWS IMMUNOLOGY 3(2):97-107 Peterlin BM; Trono D Hide, shield and strike back: How HIV-infected cells avoid immune eradication	0	4
110	11	66	110 2003 NATURE REVIEWS IMMUNOLOGY 3(11):851-858 Stevenson M Dissecting HIV-1 through RNA interference	0	0
#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
111	16	113	111 2003 NATURE REVIEWS MOLECULAR CELL BIOLOGY 4(6):457-467 Dykxhoorn DM; Novina CD; Sharp PA Killing the messenger: Short RNAs that silence gene expression	3	15
112	5	115	112 2003 NATURWISSENSCHAFTEN 90(8):345-359 Arenz C; Schepers U RNA interference: from an ancient mechanism to a state of the art therapeutic application?	0	0
113	3	49	113 2003 NUCLEIC ACIDS RESEARCH 31(2):589-595 Amarzguioui M; Holen T; Babaie E; Prydz H Tolerance for mutations and chemical modifications in a siRNA	6	16
114	2	54	114 2003 NUCLEIC ACIDS RESEARCH 31(2):670-682 Czauderna F; Fechtner M; Aygun H; Arnold W; Klippel A; Giese K; Kaufmann J Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA	3	8
115	2	59	115 2003 NUCLEIC ACIDS RESEARCH 31(2):700-707 Kawasaki H; Taira K Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells	5	14
116	2	56	116 2003 NUCLEIC ACIDS RESEARCH 31(8):2117-2126 Hemmings-Mieszczak M; Dorn G; Natt FJ; Hall J; Wishart WL Independent combinatorial effect of antisense oligonucleotides and RNAi-mediated specific inhibition of the recombinant Rat P2X(3) receptor	0	3
117	4	15	117 2003 NUCLEIC ACIDS RESEARCH 31(15):- Matsukura S; Jones PA; Takai D Establishment of conditional vectors for hairpin siRNA knockdowns	0	5
118	6	31	118 2003 NUCLEIC ACIDS RESEARCH 31(17):- Xia XG; Zhou HX; Ding HL; Affar EB; Shi Y; Xu ZS An enhanced U6 promoter for synthesis of short hairpin RNA	0	1
119	3	50	119 2003 NUCLEIC ACIDS RESEARCH 31(17):- Husken D; Asselbergs F; Kinzel B; Natt F; Weiler J; Martin P; Haner R; Hall J mRNA fusion constructs serve in a general cell-based assay to profile oligonucleotide activity	0	0
120	3	27	120 2003 NUCLEIC ACIDS RESEARCH 31(17):5033-5038 Boden D; Pusch O; Lee F; Tucker L; Shank PR; Ramratnam B Promoter choice affects the potency of HIV-1 specific RNA interference	2	2
#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
121	7	29	121 2003 NUCLEIC ACIDS RESEARCH 31(21):- Czauderna F; Santel A; Hinz M; Fechtner M; Durieux B; Fisch G; Leenders F; Arnold W; Giese K; Klippel A; Kaufmann J Inducible shRNA expression for application in a prostate cancer mouse model	0	0
122	8	26	122 2003 NUCLEIC ACIDS RESEARCH 31(22):6444-6449 Pusch O; Boden D; Silbermann R; Lee F; Tucker L; Ramratnam B Nucleotide sequence homology requirements of HIV-1-specific short hairpin RNA	0	0
123	2	33	123 2003 NUCLEIC ACIDS RESEARCH 31(24):7280-7301 Ding Y; Lawrence CE A statistical sampling algorithm for RNA secondary structure prediction	0	0
124	2	99	124 2003 ONCOGENE 22(33):5122-5130 Israel BF; Kenney SC Virally targeted therapies for EBV-associated malignancies	0	0
125	2	19	125 2003 ONCOGENE 22(36):5712-5715 Tomar RS; Matta H; Chaudhary PM Use of adeno-associated viral vector for delivery of small interfering RNA	0	0
126	4	46	126 2003 ONCOGENE 22(38):5938-5945 Butz K; Ristriani T; Hengstermann A; Denk C; Scheffner M; Hoppe-Seyler F siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells	0	0
127	14	176	127 2003 PHARMACOLOGICAL REVIEWS 55(4):629-648 Milhavet O; Gary DS; Mattson MP RNA interference in biology and medicine	0	0
128	1	107	128 2003 PHYSIOLOGICAL GENOMICS 13(1):15-24 Barr MM Super models	0	2
129	3	61	129 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(1):183-188 Qin XF; An DS; Chen ISY; Baltimore D Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5	23	43
130	3	47	130 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(1):235-240 Randall G; Grakoui A; Rice CM Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs	12	30
#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
131	5	39	131 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(5):2783-2788 Wilson JA; Jayasena S; Khvorova A; Sabatinos S; Rodrigue-Gervais IG; Arya S; Sarangi F; Harris-Brandts M; Beaulieu S; Richardson CD RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells	11	22
132	3	27	132 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(13):7797-7802 Zender L; Hutker S; Liedtke C; Tillmann HL; Zender S; Mundt B; Waltemathe M; Gosling T; Flemming P; Malek NP; Trautwein C; Manns MP; Kuhnel F; Kubicka S Caspase 8 small interfering RNA prevents acute liver failure in mice	1	8
133	9	20	133 2003 PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 30(4):650-654 Chen J; Bai CX; Zhang M Application of RNA interference in mammalian cells	0	0
134	1	81	134 2003 RECOGNITION OF CARBOHYDRATES IN BIOLOGICAL SYSTEMS, PART B: SPECIFIC APPLICATIONS 363():173-190 Diallo M; Arenz C; Schmitz K; Sandhoff K; Schepers U RNA interference: Analyzing the function of glycoproteins and glycosylating proteins in mammalian cells	1	1
135	2	70	135 2003 REPRODUCTION 126(1):1-11 Denning C; Priddle H New frontiers in gene targeting and cloning: success, application and challenges in domestic animals and human embryonic stem cells	0	2
136	1	36	136 2003 RNA-A PUBLICATION OF THE RNA SOCIETY 9(6):648-653 Carnes J; Jacobson M; Leinwand L; Yarus M Stop codon suppression via inhibition of eRF1 expression	0	0
137	1	29	137 2003 RNA-A PUBLICATION OF THE RNA SOCIETY 9(10):1254-1263 Byun J; Lan N; Long M; Sullenger BA Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes	0	0
138	5	84	138 2003 SEMINARS IN CANCER BIOLOGY 13(4):283-292 Damm-Welk C; Fuchs U; Wossmann W; Borkhardt A Targeting oncogenic fusion genes in leukemias and lymphomas by RNA interference	0	0
139	3	23	139 2003 STEM CELLS 22(1):93-99 Tang FC; Meng GL; Yang HB; Li CJ; Shi Y; Ding MX; Shang KG; Zhang B; Xue YF Stable suppression of gene expression in murine embryonic stem cells by RNAi directed from DNA vector-based short hairpin RNA	0	0
140	3	17	140 2003 TRENDS IN BIOTECHNOLOGY 21(1):2-4 Voorhoeve PM; Agami R Knockdown stands up	2	4
#	LCR	NCR	Nodes / Authors / Date	LCS	GCS
141	5	24	141 2003 TRENDS IN BIOTECHNOLOGY 21(7):306-311 Brisibe EA; Okada N; Mizukami H; Okuyama H; Fujii YR RNA interference: potentials for the prevention of HIV infections and the challenges ahead	0	0
142	3	43	142 2003 TRENDS IN GENETICS 19(1):9-12 Shi Y Mammalian RNAi for the masses	5	26
143	14	94	143 2003 TRENDS IN MOLECULAR MEDICINE 9(9):397-403 Lieberman J; Song E; Lee SK; Shankar P Interfering with disease: opportunities and roadblocks to harnessing RNA interference	0	0
144	8	64	144 2003 VIRUS RESEARCH 96(1-2):27-35 Sen A; Steele R; Ghosh AK; Basu A; Ray R; Ray RB Inhibition of hepatitis C virus protein expression by RNA interference	0	0
145	14	73	145 2003 WORLD JOURNAL OF GASTROENTEROLOGY 9(8):1657-1661 Wang QC; Nie QH; Feng ZH RNA interference: Antiviral weapon and beyond	0	0
146	16	82	146 2004 ANNALS OF HEMATOLOGY 83(1):1-8 Scherr M; Steinmann D; Eder M RNA interference (RNAi) in hematology	0	0
147	6	28	147 2004 BIOTECHNIQUES 36(1):74-+ Kojima SI; Vignjevic D; Borisy GG Improved silencing vector co-expressing GFP and small hairpin RNA	0	0
148	1	46	148 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(1):16-22 Matsuda T; Cepko CL Electroporation and RNA interference in the rodent retina in vivo and in vitro	0	0

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