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Tue Sep 14 12:29:25 2004

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
Lando D, Peet DJ, Gorman JJ, Whelan DA, Whitelaw ML, Bruick RK
GENES & DEVELOPMENT 16 (12): 1466-1471 JUN 15 2002
and the citing papers

Nodes: 99
Authors: 344, Journals: 63, Outer References: 3157
Collection span: 2002 - 2004
View: Overview. Sorted by year, source, volume, issue, page.
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
11311 2002 BIOCHEMICAL JOURNAL 367:571-575
McNeill LA; Hewitson KS; Claridge TD; Seibel JF; Horsfall LE; Schofield CJ
Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803
1822
21492 2002 BLOOD PURIFICATION 20(5):445-450
Ratcliffe PJ
From erythropoietin to oxygen: Hypoxia-inducible factor hydroxylases and the hypoxia signal pathway
16
31493 2002 CELL 111(5):709-720
Jeong JW; Bae MK; Ahn MY; Kim SH; Sohn TK; Bae MH; Yoo MA; Song EJ; Lee KJ; Kim KW
Regulation and destabilization of HIF-1 alpha by ARD1-mediated acetylation
1943
45964 2002 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 67:133-142
Arbeit JM
Quiescent hypervascularity mediated by Gain of HIF-1 alpha function
00
51415 2002 GENES & DEVELOPMENT 16(12):1441-1445
Kaelin WG
How oxygen makes its presence felt
731
60346 2002 GENES & DEVELOPMENT 16(12):1466-1471
Lando D; Peet DJ; Gorman JJ; Whelan DA; Whitelaw ML; Bruick RK
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
9898
72467 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(42):39792-39800
Huang JH; Zhao Q; Mooney SM; Lee FS
Sequence determinants in hypoxia-inducible factor-1 alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3
2139
81538 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(44):41750-41755
Huang LE; Pete EA; Schau M; Milligan J; Gu J
Leu-574 of HIF-1 alpha is essential for the von Hippel-Lindau (VHL)-mediated degradation pathway
37
911119 2002 MASS SPECTROMETRY REVIEWS 21(3):183-216
Gorman JJ; Wallis TP; Pitt JJ
Protein disulfide bond determination by mass spectrometry
08
1013810 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(18):11570-11572
Semenza GL
Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1 alpha with p300 and CBP
15
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
1114211 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(24):15351-15356
Dann CE; Bruick RK; Deisenhofer J
Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway
1527
1237112 2003 ANNALS OF MEDICINE 35(3):183-190
Wiesener MS; Maxwell PH
HIF and oxygen sensing; as important to life as the air we breathe?
16
13510913 2003 ANNALS OF MEDICINE 35(6):380-390
Pugh CW
Oxygen sensing in cancer
00
1477114 2003 BIOCHEMICAL SOCIETY TRANSACTIONS 31:510-515
Hewitson KS; McNeill LA; Elkins JM; Schofield CJ
The role of iron and 2-oxoglutarate oxygenases in signalling
24
1512515 2003 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 13(8):1451-1454
Schlemminger I; Mole DR; McNeill LA; Dhanda A; Hewitson KS; Tian YM; Ratcliffe PJ; Pugh CW; Schofield CJ
Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases
34
1632916 2003 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 13(16):2677-2680
Mole DR; Schlemminger I; McNeill LA; Hewitson KS; Pugh CW; Ratcliffe PJ; Schofield CJ
2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase
23
1712117 2003 BREAST CANCER RESEARCH 5(6):R223-R230
Cayre A; Rossignol F; Clottes E; Penault-Llorca F
aHIF but not HIF-1 alpha transcript is a poor prognostic marker in human breast cancer
01
1812218 2003 CANCER RESEARCH 63(8):1764-1768
Knowles HJ; Raval RR; Harris AL; Ratcliffe PJ
Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells
515
19126019 2003 CELLULAR AND MOLECULAR LIFE SCIENCES 60(7):1376-1393
Bracken CP; Whitelaw ML; Peet DJ
The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses
24
20110520 2003 CRITICAL CARE MEDICINE 31(12):S651-S657
Scharte M; Fink MP
Red blood cell physiology in critical illness
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
21514621 2003 CURRENT MEDICINAL CHEMISTRY 10(12):1005-1019
Hanauske-Abel HM; Popowicz AM
The HAG mechanism: A molecular rationale for the therapeutic application of iron chelators in human diseases involving the 2-oxoacid utilizing dioxygenases
00
2226022 2003 CURRENT OPINION IN GENETICS & DEVELOPMENT 13(1):55-60
Kim W; Kaelin WG
The von Hippel-Lindau tumor suppressor protein: new insights into oxygen sensing and cancer
211
2366223 2003 CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(6):650-656
Binley K; Kan O; White J; Naylor S
Exploiting the hypoxia response
01
2426224 2003 CURRENT PHARMACEUTICAL DESIGN 9(7):531-541
Mazure NM; Brahimi-Horn MC; Pouyssegur J
Protein kinases and the hypoxia-inducible factor-1, two switches in angiogenesis
112
2515225 2003 EMBO JOURNAL 22(8):1857-1867
Li ZB; Wang DK; Na X; Schoen SR; Messing EM; Wu G
The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1 alpha transcriptional activity
25
2644926 2003 EMBO JOURNAL 22(16):4082-4090
Berra E; Benizri E; Ginouves A; Volmat V; Roux D; Pouyssegur J
HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1 alpha in normoxia
1025
27312127 2003 EUROPEAN JOURNAL OF BIOCHEMISTRY 270(5):781-790
Lando D; Gorman JJ; Whitelaw ML; Peet DJ
Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation
716
2826928 2003 EUROPEAN JOURNAL OF BIOCHEMISTRY 270(5):791-798
Bilton RL; Booker GW
The subtle side to hypoxia inducible factor (HIF alpha) regulation
311
2914529 2003 FASEB JOURNAL 17(6)
Warnecke C; Griethe W; Weidemann A; Jurgensen JS; Willam C; Bachmann S; Ivashchenko Y; Wagner I; Frei U; Wiesener M; Eckardt KU
Activation of the hypoxia-inducible factor pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors
00
3013630 2003 FASEB JOURNAL 17(15)
Moon EJ; Jeong CH; Jeong JW; Kim KR; Yu DY; Murakami S; Kim CW; Kim KW
Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1 alpha
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
3112831 2003 FEBS LETTERS 549(1-3):105-109
Yasinska IM; Sumbayev VV
S-nitrosation of Cys-800 of HIF-1 alpha protein activates its interaction with p300 and stimulates its transcriptional activity
12
32112832 2003 FRONTIERS IN BIOSCIENCE 8:D100-D116
Brat DJ; Kaur B; Van Meir EG
Genetic modulation of hypoxia induced gene expression and angiogenesis: Relevance to brain tumors
05
33118933 2003 GENES & DEVELOPMENT 17(21):2614-2623
Bruick RK
Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor
212
3414934 2003 HEARING RESEARCH 183(1-2):73-83
Gross J; Rheinlander C; Fuchs J; Mazurek B; Machulik A; Andreeva N; Kietzmann T
Expression of hypoxia-inducible factor-1 in the cochlea of newborn rats
00
3529935 2003 JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY 36(1):120-127
Choi KS; Bae MK; Jeong JW; Moon HE; Kim KW
Hypoxia-induced angiogenesis during carcinogenesis
06
3612936 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(3):1802-1806
Elkins JM; Hewitson KS; McNeill LA; Seibel JF; Schlemminger I; Pugh CW; Ratcliffe PJ; Schofield CJ
Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha
1625
3723737 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(9):6816-6823
Pereira T; Zheng XW; Ruas JL; Tanimoto K; Poellinger L
Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor gene product
28
3813938 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(9):7558-7563
Lee C; Kim SJ; Jeong DG; Lee SM; Ryu SE
Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau
1114
3915539 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(16):14013-14019
Sang NL; Stiehl DP; Bohensky J; Leshchinsky I; Srinivas V; Caro J
MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300
720
4037940 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(22):19575-19578
Huang LE; Bunn HF
Hypoxia-inducible factor and its biomedical relevance
1021
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
4113441 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(22):20235-20239
Wright G; Higgin JJ; Raines RT; Steenbergen C; Murphy E
Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes
23
4223642 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(34):31895-31901
Naranjo-Suarez S; Castellanos MC; Alvarez-Tejado M; Vara A; Landazuri MO; del Peso L
Down-regulation of hypoxia-inducible factor-2 in PC12 cells by nerve growth factor stimulation
02
4315843 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(35):33384-33391
Kodama T; Shimizu N; Yoshikawa N; Makino Y; Ouchida R; Okamoto K; Hisada T; Nakamura H; Morimoto C; Tanaka H
Role of the glucocorticoid receptor for regulation of hypoxia-dependent gene expression
00
4416344 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(38):35878-35888
Lees MJ; Peet DJ; Whitelaw ML
Defining the role for XAP2 in stabilization of the dioxin receptor
02
4532045 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(40):38183-38187
D'Angelo G; Duplan E; Boyer N; Vigne P; Frelin C
Hypoxia up-regulates prolyl hydroxylase activity - A feedback mechansim that limits HIF-1 responses during reoxygenation
06
4615546 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(40):39076-39084
Yoo YG; Oh SH; Park ES; Cho H; Lee N; Park H; Kim DK; Yu DY; Seong JK; Lee MO
Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1 alpha through activation of mitogen-activated protein kinase pathway
00
4723247 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(41):40337-40342
Hanson ES; Rawlins ML; Leibold EA
Oxygen and iron regulation of iron regulatory protein 2
39
4836648 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(50):50771-50780
Hon T; Dodd A; Dirmeier R; Gorman N; Sinclair PR; Zhang L; Poyton RO
A mechanism of oxygen sensing in yeast - Multiple oxygen-responsive steps in the heme biosynthetic pathway affect Hap1 activity
00
4924249 2003 JOURNAL OF CELL SCIENCE 116(7):1319-1326
Metzen E; Berchner-Pfannschmidt U; Stengel P; Marxsen JH; Stolze I; Klinger M; Huang WQ; Wotzlaw C; Hellwig-Burgel T; Jelkmann W; Acker H; Fandrey J
Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing
922
5079750 2003 JOURNAL OF CELL SCIENCE 116(15):3041-3049
Masson N; Ratcliffe PJ
HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O-2 levels
38
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
5117551 2003 JOURNAL OF CLINICAL INVESTIGATION 111(6):779-783
Safran M; Kaelin WG
HIF hydroxylation and the mammalian oxygen-sensing pathway
423
52610452 2003 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 14(11):2712-2722
Maxwell P
HIF-1: An oxygen response system with special relevance to the kidney
12
5324953 2003 MOLECULAR AND CELLULAR BIOLOGY 23(14):4959-4971
Park SK; Dadak AM; Haase VH; Fontana L; Giaccia AJ; Johnson RS
Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1 alpha (HIF-1 alpha): Role of cytoplasmic trapping of HIF-2 alpha
314
54311154 2003 MOLECULAR AND CELLULAR BIOLOGY 23(24):9361-9374
Hu CJ; Wang LY; Chodosh LA; Keith B; Simon MC
Differential roles of hypoxia-inducible factor 1 alpha (HIF-1 alpha) and HIF-2 alpha in hypoxic gene regulation
16
5525955 2003 MOLECULAR BIOLOGY OF THE CELL 14(8):3470-3481
Metzen E; Zhou J; Jelkmann W; Fandrey J; Brune B
Nitric oxide impairs normoxic degradation of HIF-1 alpha by inhibition of prolyl hydroxylases
713
56311556 2003 NATURE MEDICINE 9(6):677-684
Pugh CW; Ratcliffe PJ
Regulation of angiogenesis by hypoxia: role of the HIF system
866
57310757 2003 NATURE REVIEWS CANCER 3(10):721-732
Semenza GL
Targeting HIF-1 for cancer therapy
747
58411658 2003 NATURE REVIEWS DRUG DISCOVERY 2(10):803-811
Giaccia A; Siim BG; Johnson RS
HIF-1 as a target for drug development
315
5954859 2003 NATURE STRUCTURAL BIOLOGY 10(7):504-512
Freedman SJ; Sun ZYJ; Kung AL; France DS; Wagner G; Eck MJ
Structural basis for negative regulation of hypoxia-inducible factor-1 alpha by CITED2
16
6022660 2003 PHARMACOLOGY 69(2):74-78
Meissner U; Allabauer I; Repp R; Rascher W; Dotsch J
Inducible expression of hypoxia-inducible factor 1 alpha (HIF-1 alpha) as a tool for studying HIF-1 alpha-dependent gene regulation during normoxia in vitro
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
6115561 2003 PLACENTA 24(2-3):199-208
Rajakumar A; Doty K; Daftary A; Harger G; Conrad KP
Impaired oxygen-dependent reduction of HIF-1 alpha and -2 alpha proteins in pre-eclamptic placentae
47
6225762 2003 PLACENTA 24(10):941-950
Schaffer L; Scheid A; Spielmann P; Breymann C; Zimmermann R; Meuli M; Gassmann M; Marti HH; Wenger RH
Oxygen-regulated expression of TGF-beta 3, a growth factor involved in trophoblast differentiation
12
63135263 2003 REVIEWS OF PHYSIOLOGY, BIOCHEMISTRY AND PHARMACOLOGY, VOL 146 146:159-216
Fluck M; Hoppeler H
Molecular basis of skeletal muscle plasticity-from gene to form and function
08
6417864 2003 SEMINARS IN CANCER BIOLOGY 13(1):83-89
Pugh CW; Ratcliffe PJ
The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis
021
6515965 2003 THROMBOSIS AND HAEMOSTASIS 89(5):926-935
Gorlach A; Berchner-Pfannschmidt U; Wotzlaw C; Cool RH; Fandrey J; Acker H; Jungermann K; Kietzmann T
Reactive oxygen species modulate HIF-1 mediated PAI-1 expression: involvement of the GTPase Rac1
26
66716566 2004 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 286(6):R977-R988
Fandrey J
Oxygen-dependent and tissue-specific regulation of erythropoietin gene expression
00
6728967 2004 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 287(1):F1-F6
Sufan RI; Jewett MAS; Ohh M
The role of von Hippel-Lindau tumor suppressor protein and hypoxia in renal clear cell carcinoma
00
68313368 2004 ANTIOXIDANTS & REDOX SIGNALING 6(4):777-791
Dimova EY; Samoylenko A; Kietzmann T
Oxidative stress and hypoxia: Implications for plasminogen activator inhibitor-1 expression
01
6973269 2004 BIOCHEMICAL JOURNAL 380:419-424
Dalgard CL; Lu HS; Mohyeldin A; Verma A
Endogenous 2-oxoacids differentially regulate expression of oxygen sensors
00
7058470 2004 BIOESSAYS 26(3):262-269
Bardos JI; Athcroft M
Hypoxia-inducible factor-1 and oncogenic signalling
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
71189071 2004 BIOLOGICAL CHEMISTRY 385(3-4):223-230
Metzen E; Ratcliffe PJ
HIF hydroxylation and cellular oxygen sensing
00
7232172 2004 BMC CELL BIOLOGY 5
Cikala M; Alexandrova O; David CN; Proschel M; Stiening B; Cramer P; Bottger A
The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity
00
73610073 2004 CANCER BIOLOGY & THERAPY 3(1):29-35
Maxwell P; Salnikow K
HIF-1 - An oxygen and metal responsive transcription factor
00
7445374 2004 CANCER CELL 6(1):33-43
Kung AL; Zabludoff SD; France DS; Freedman SJ; Tanner EA; Vieira A; Cornell-Kennon S; Lee J; Wang BQ; Wang JM; Memmert K; Naegeli HU; Petersen F; Eck MJ; Bair KW; Wood AW; Livingston DM
Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway
00
75412875 2004 CARDIOVASCULAR RESEARCH 61(3):437-447
Chi NC; Karliner JS
Molecular determinants of responses to myocardial ischemia/reperfusion injury: focus on hypoxia-inducible and heat shock factors
01
761714476 2004 CURRENT PHARMACEUTICAL DESIGN 10(8):821-833
Hewitson KS; McNeill LA; Schofield CJ
Modulating the hypoxia-inducible factor signaling pathway: Applications from cardiovascular disease to cancer
01
77812377 2004 EXPERIMENTAL AND MOLECULAR MEDICINE 36(1):1-12
Lee JW; Bae SH; Jeong JW; Kim SH; Kim KW
Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions
00
7823778 2004 EXPERIMENTAL CELL RESEARCH 295(2):340-349
Piret JP; Lecocq C; Toffoli S; Ninane N; Raes M; Michiels C
Hypoxia and CoCl2 protect HepG2 cells against serum deprivation-and t-BHP-induced apoptosis: a possible anti-apoptotic role for HIF-1
00
791318579 2004 EXPERT OPINION ON THERAPEUTIC PATENTS 14(7):951-966
Zhong H
Targeting hypoxia-inducible factor-1 for therapy and prevention
00
8074380 2004 FASEB JOURNAL 18(6)
Kageyama Y; Koshiji M; To KKW; Tian YM; Ratcliffe PJ; Huang LE
Leu-574 of human HIF-1a is a molecular determinant of prolyl hydroxylation
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
8144481 2004 FASEB JOURNAL 18(10)
Warnecke C; Zaborowska Z; Kurreck J; Erdmann VA; Frei U; Wiesener M; Eckardt KU
Differentiating the functional role of hypoxia-inducible factor (HIF)-1 alpha and HIF-2 alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2 alpha target gene in Hep3B and Kelly cells
00
82110482 2004 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 36(2):189-204
Kewley RJ; Whitelaw ML; Chapman-Smith A
The mammalian basic helix-loop-helix/PAS family of transcriptional regulators
03
8324783 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(4):2550-2558
Kasuno K; Takabuchi S; Fukuda K; Kizaka-Kondoh S; Yodoi J; Adachi T; Semenza GL; Hirota K
Nitric oxide induces hypoxia-inducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling
12
8455784 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(10):9504-9511
Martin-Puig S; Temes E; Olmos G; Jones DR; Aragones J; Landazuri MO
Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms
11
8573185 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(11):9899-9904
Koivunen P; Hirsila M; Gunzler V; Kivirikko KI; Myllyharju J
Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases
11
8683586 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(14):14391-14397
Linke S; Stojkoski C; Kewley RJ; Booker GW; Whitelaw ML; Peet DJ
Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor
22
8764287 2004 JOURNAL OF CELLULAR BIOCHEMISTRY 92(3):491-501
Aprelikova O; Chandramouli GVR; Wood M; Vasselli JR; Riss J; Maranchie JK; Linehan WM; Barrett JC
Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors
00
8813288 2004 JOURNAL OF CLINICAL PATHOLOGY 57(7):706-711
Morris MR; Maina EN; Morgan NV; Gentle D; Astuti D; Moch H; Kishida T; Yao M; Schraml P; Richards FM; Latif F; Maher ER
Molecular genetic analysis of FIH-1, FH, and SDHB candidate tumour suppressor genes in renal cell carcinoma
00
8937489 2004 JOURNAL OF PHARMACOLOGICAL SCIENCES 94(3):221-232
Park JW; Chun YS; Kim NS
Hypoxia-inducible factor 1-related diseases and prospective therapeutic tools
00
9046490 2004 MOLECULAR BIOLOGY 38(1):47-57
Turpaev KT; Litvinov DY
Redox-dependent regulation of the expression of nitric oxide-inducible genes
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
911810891 2004 NATURE REVIEWS MOLECULAR CELL BIOLOGY 5(5):343-354
Schofield CJ; Ratcliffe PJ
Oxygen sensing by HIF hydroxylases
00
92819092 2004 NATURE REVIEWS NEUROSCIENCE 5(6):437-448
Sharp FR; Bernaudin M
HIf1 and oxygen sensing in the brain
00
9312393 2004 ONCOGENE 23(13):2315-2323
Lewis MD; Roberts BJ
Role of the C-terminal alpha-helical domain of the von Hippel-Lindau protein in its E3 ubiquitin ligase activity
00
9422794 2004 OXYGEN SENSING 381:305-320
Masson N; Ratcliffe PJ
Analysis of von Hippel-Lindau tumor suppressor as a mediator of cellular oxygen sensing
00
9533495 2004 OXYGEN SENSING 381:467-487
Peet DJ; Lando D; Whelan DA; Whitelaw ML; Gorman JJ
Oxygen-dependent asparagine hydroxylation
00
9626896 2004 OXYGEN SENSING 381:488-510
Acker H; Huckstorf C; Sauer H; Streller T; Wartenberg M
Deciphering the oxygen sensing pathway by microscopy
00
9714097 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(12):4302-4307
Liu Q; Berchner-Pfannschmidt U; Moller U; Brecht M; Wotzlaw C; Acker H; Jungermann K; Kietzmann T
A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression
12
9836998 2004 SEMINARS IN RADIATION ONCOLOGY 14(3):207-214
Leo C; Giaccia AJ; Denko NC
The hypoxic tumor microenvironment and gene expression
00
9934099 2004 TOXICOLOGY AND APPLIED PHARMACOLOGY 196(2):258-265
Salnikow K; Li XM; Lippmann M
Effect of nickel and iron co-exposure on human lung cells
00

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