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Mon Aug 28 12:20:33 2006

A gain-of-function mutation of JAK2 in myeloproliferative disorders
Kralovics R, Passamonti F, Buser AS, Teo S, Tiedt R, et al.
NEW ENGLAND JOURNAL OF MEDICINE 352 (17): 1779-1790 APR 28 2005
and the citing papers
Nodes: 169, Authors: 715, Journals: 56, Cited References: 4826, Words: 597
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Collection span: 2005 - 2006
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#LCRNCRNode / Date / Journal / AuthorLCSGCS
101111101 2006 CANCER GENETICS AND CYTOGENETICS 164 (1): 90-91
Nunoda K; Sashida G; Ohyashiki K; Kodama A; Fukutake K
The translocation (4;12)(q31;q21) in myelofibrosis associated with myelodysplastic syndrome: impact of the 12q21 breakpoint
00
102114102 2006 CANCER GENETICS AND CYTOGENETICS 165 (1): 87-89
Lazarevic V; Andersson C; Wahlin A; Golovleva I
Chromosome aberrations including, der(6)t(2;6)(p15;p21.3) and der(22)t(3;22)(p21;p11) in the evolution of essential thrombocythemia to myelofibrosis with myeloid metaplasia
00
103115103 2006 CANCER GENETICS AND CYTOGENETICS 167 (1): 74-77
Cesar JM; Cabello P; Ferro T; Navarro JL
Emergence of chronic myelogenous leukemia in a patient with primary thrombocythemia and absence of BCR/ABL rearrangement
00
104120104 2006 CANCER RESEARCH 66 (13): 6468-6472
Samanta AK; Lin H; Sun T; Kantarjian H; Arlinghaus RB
Janus kinase 2: A critical target in chronic myelogenous leukemia
00
10526105 2006 CLINICAL CHEMISTRY 52 (7): 1436-1438
Sidon P; Heimann P; Lambert F; Dessars B; Robin V; et al.
Combined locked nucleic acid and molecular beacon technologies for sensitive detection of the JAK2(V617F) somatic single-base sequence variant
00
1062200106 2006 CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY 57 (2): 145-164
Walz C; Sattler M
Novel targeted therapies to overcome imatinib mesylate resistance in chronic myeloid leukemia (CML)
01
107277107 2006 CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY 57 (3): 245-253
Bruns HA; Kaplan MH
The role of constitutively active Stat6 in leukemia and lymphoma
00
108146108 2006 CURRENT OPINION IN ONCOLOGY 18 (1): 62-68
Taki T; Taniwaki M
Chromosomal translocations in cancer and their relevance for therapy
00
1093198109 2006 CURRENT PHARMACEUTICAL BIOTECHNOLOGY 7 (3): 185-198
Oveland E; Fladmark KE; Wergeland L; Gjertsen BT; Hovland R
Proteomics approaches to elucidate oncogenic tyrosine kinase signaling in myeloid malignancies
00
110620110 2006 EUROPEAN JOURNAL OF HAEMATOLOGY 77 (1): 57-60
Thurmes PJ; Steensma DP
Elevated serum erythropoietin levels in patients with Budd-Chiari syndrome secondary to polycythemia vera: clinical implications for the role of JAK2 mutation analysis
00
#LCRNCRNode / Date / Journal / AuthorLCSGCS
1111023111 2006 EUROPEAN JOURNAL OF HAEMATOLOGY 77 (3): 210-216
Heller PG; Lev PR; Salim JP; Kornblihtt LI; Goette NP; et al.
JAK2V617F mutation in platelets from essential thrombocythemia patients: correlation with clinical features and analysis of STAT5 phosphorylation status
00
112234112 2006 GASTROENTEROLOGY 130 (7): 2031-2038
Patel RK; Lea NC; Heneghan MA; Westwood NB; Milojkovic D; et al.
Prevalence of the activating JAK2 tyrosine kinase mutation V617F in the Budd-Chiari syndrome
00
113272113 2006 GROWTH FACTORS 24 (1): 89-95
Ingley E; Klinken SP
Cross-regulation of JAK and Src kinases
00
1142034114 2006 HAEMATOLOGICA-THE HEMATOLOGY JOURNAL 91 (2): 159-161
Cazzola M; Passamonti F
Not just clonal expansion of hematopoietic cells, but also activation of their progeny in the pathogenesis of myeloproliferative disorders
00
115436115 2006 HAEMATOLOGICA-THE HEMATOLOGY JOURNAL 91 (2): 169-175
Arellano-Rodrigo E; Alvarez-Larran A; Reverter JC; Villamor N; Colomer D; et al.
Increased platelet and leukocyte activation as contributing mechanisms for thrombosis in essential thrombocythemia and correlation with the JAK2 mutational status
33
116510116 2006 HAEMATOLOGICA-THE HEMATOLOGY JOURNAL 91 (3): 411-412
Mnjoyan Z; Yoon D; Li J; Delhommeau F; Ashar-Kharghan V
The effect of the JAK2 V617F mutation on PRV-1 expression
00
11719117 2006 HAEMATOLOGICA-THE HEMATOLOGY JOURNAL 91 (3): 413-414
Percy MJ; Jones FGC; Creen AR; Reilly JT; McMullin MF
The incidence of the JAK2 V617F mutation in patients with idiopathic erythrocytosis
00
118122118 2006 HAEMATOLOGICA-THE HEMATOLOGY JOURNAL 91 (8): 1100-1104
Vassiliou GS; Campbell PJ; Li J; Roberts I; Swanton S; et al.
An acquired translocation in JAK2 Val617Phe-negative essential thrombocythemia associated with autosomal spread of X-inactivation
00
1192115119 2006 HEMATOLOGICAL ONCOLOGY 24 (2): 56-63
Reilly JT
Idiopathic myelofibrosis: pathogenesis to treatment
00
120415120 2006 HUMAN PATHOLOGY 37 (4): 500-502
Tzankov A; Heiss S
Myeloproliferative disorders carrying the t(8;9) (PCM1-JAK2) transtocation - reply
00
#LCRNCRNode / Date / Journal / AuthorLCSGCS
121228121 2006 INTERNATIONAL JOURNAL OF HEMATOLOGY 83 (5): 443-449
Dan K; Yamada T; Kimura Y; Usui N; Okamoto S; et al.
Clinical features of polycythemia vera and essential thrombocythemia in Japan: Retrospective analysis of a nationwide survey by the Japanese Elderly Leukemia and Lymphoma Study Group
00
122442122 2006 JOURNAL OF BIOLOGICAL CHEMISTRY 281 (26): 18177-18183
Walz C; Crowley BJ; Hudon HE; Gramlich JL; Neuberg DS; et al.
Activated Jak2 with the V617F point mutation promotes G(1)/S phase transition
00
123145123 2006 JOURNAL OF IMMUNOLOGY 176 (11): 6425-6433
Wagner-Ballon O; Chagraoui H; Prina E; Tulliez M; Milon G; et al.
Monocyte/macrophage dysfunctions do not impair the promotion of myelofibrosis by high levels of thrombopoietin
00
124918124 2006 JOURNAL OF MOLECULAR DIAGNOSTICS 8 (3): 299-304
Horn T; Kremer M; Dechow T; Pfeifer WM; Geist B; et al.
Detection of the activating JAK2 V617F mutation in paraffin-embedded trephine bone marrow biopsies of patients with chronic myeloproliferative diseases
00
125710125 2006 JOURNAL OF MOLECULAR DIAGNOSTICS 8 (3): 330-334
Lay M; Mariappan R; Gotlib J; Dietz L; Sebastian S; et al.
Detection of the JAK2 V617F mutation by LightCycler PCR and probe dissociation analysis
00
126127126 2006 LEUKEMIA 20 (1): 55-60
Cervantes F; Alvarez-Larran A; Arellano-Rodrigo E; Granell M; Domingo A; et al.
Frequency and risk factors for thrombosis in idiopathic myelofibrosis: analysis in a series of 155 patients from a single institution
00
127210127 2006 LEUKEMIA 20 (1): 157-158
Melzner I; Weniger MA; Menz CK; Moller P
Absence of the JAK2 V617F activating mutation in classical Hodgkin lymphoma and primary mediastinal B-cell lymphoma
00
12838128 2006 LEUKEMIA 20 (1): 168-171
McClure R; Mai M; Lasho T
Validation of two clinically useful assays for evaluation of JAK2 V617F mutation in chronic myeloproliferative disorders
23
129669129 2006 LEUKEMIA 20 (2): 200-205
De Keersmaecker K; Cools J
Chronic myeloproliferative disorders: a tyrosine kinase tale
24
13028130 2006 LEUKEMIA 20 (2): 350-353
James C; Delhommeau F; Marzac C; Teyssandier I; Le Couedic JP; et al.
Detection of JAK2 V617F as a first intention diagnostic test for erythrocytosis
45
#LCRNCRNode / Date / Journal / AuthorLCSGCS
131522131 2006 LEUKEMIA 20 (3): 471-476
Quentmeier H; Macleod RAF; Zaborski M; Drexler HG
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders
11
132610132 2006 LEUKEMIA 20 (3): 534-535
Vizmanos JL; Ormazabal C; Larrayoz MJ; Cross NCP; Calasanz MJ
JAK2 V617F mutation in classic chronic myeloproliferative diseases: a report on a series of 349 patients
11
13329133 2006 LEUKEMIA 20 (3): 547-548
Desta F; Christiansen DH; Andersen MK; Pedersen-Bjergaard J
Activating mutations of JAK2V617F are uncommon in t-MDS and t-AML and are only observed in atypic cases
00
13449134 2006 LEUKEMIA 20 (4): 736-737
Bellosillo B; Besses C; Florensa L; Sole F; Serrano S
JAK2 V617F mutation, PRV-1 overexpression and endogenous erythroid colony formation show different coexpression patterns among Ph-negative chronic myeloproliferative disorders
22
1351263135 2006 LEUKEMIA 20 (6): 971-978
Steensma DP; McClure RF; Karp JE; Tefferi A; Lasho TL; et al.
JAK2 V617F is a rare finding in de novo acute myeloid leukemia, but STAT3 activation is common and remains unexplained
11
1361028136 2006 LEUKEMIA 20 (6): 1055-1060
Vannucchi AM; Pancrazzi A; Bogani C; Antonioli E; Guglielmelli P
A quantitative assay for JAK2(V617F) mutation in myeloproliferative disorders by ARMS-PCR and capillary electrophoresis
11
13727137 2006 LEUKEMIA 20 (6): 1168-1169
Suzuki M; Abe A; Kiyoi H; Murata M; Ito Y; et al.
Mutations of N-RAS, FLT3 and p53 genes are not involved in the development of acute leukemia transformed from myeloproliferative diseases with JAK2 mutation
00
13836138 2006 LEUKEMIA 20 (7): 1297-1298
Ohyashiki K; Ohyashiki J
Reply to Kremer M et al., The JAK2 V617F mutation occurs frequently in myelodysplastic/myeloproliferative diseases, but is absent in true myelodysplastic syndromes with fibrosis
00
13979139 2006 LEUKEMIA 20 (7): 1315-1316
Kremer M; Horn T; Dechow T; Tzankov A; Quintanilla-Martinez L; et al.
The JAK2 V617F mutation occurs frequently in myelodysplastic/myeloproliferative diseases, but is absent in true myelodysplastic syndromes with fibrosis
00
14048140 2006 LEUKEMIA 20 (7): 1319-1321
Ingram W; Lea NC; Cervera J; Germing U; Fenaux P; et al.
The JAK2 V617F mutation identifies a subgroup of MDS patients with isolated deletion 5q and a proliferative bone marrow
00
#LCRNCRNode / Date / Journal / AuthorLCSGCS
14148141 2006 LEUKEMIA 20 (7): 1324-1326
Lea NC; Lim Z; Westwood NB; Arno MJ; Gaken J; et al.
Presence of JAK2 V617F tyrosine kinase mutation as a myeloid-lineage-specific mutation in chronic neutrophilic leukaemia
00
142239142 2006 LEUKEMIA 20 (8): 1414-1421
Vu H; Xinh P; Masuda M; Motoji T; Toyoda A; et al.
FLT3 is fused to ETV6 in a myeloproliferative disorder with hypereosinophilia and a t(12;13) (p13;q12) translocation
00
14348143 2006 LEUKEMIA 20 (8): 1453-1454
Park MJ; Shimada A; Asada H; Koike K; Tsuchida M; et al.
JAK2 mutation in a boy with polycythemia vera, but not in other pediatric hematologic disorders
00
1447143144 2006 LEUKEMIA & LYMPHOMA 47 (2): 177-194
Nelson ME; Steensma DP
JAK2 V617F in myeloid disorders: What do we know now, and where are we headed?
25
1454181145 2006 LEUKEMIA & LYMPHOMA 47 (3): 381-396
Thiele J; Kvasnicka HM
A critical reappraisal of the WHO classification of the chronic myeloproliferative disorders
34
1461934146 2006 LEUKEMIA RESEARCH 30 (6): 739-744
Tefferi A; Pardanani A
Mutation screening for JAK2(V617F): When to order the test and how to interpret the results
12
1477173147 2006 MAYO CLINIC PROCEEDINGS 81 (4): 553-563
Tefferi A; Elliot MA; Pardanani A
Atypical myeloproliferative disorders: Diagnosis and management
00
148179148 2006 MOLECULAR AND CELLULAR BIOLOGY 26 (11): 4052-4062
Mazurkiewicz-Munoz AM; Argetsinger LS; Kouadio JLK; Stensballe A; Jensen ON; et al.
Phosphorylation of JAK2 at serine 523: a negative regulator of JAK2 that is stimulated by growth hormone and epidermal growth factor
01
1491216149 2006 MOLECULAR CELL 22 (6): 851-868
Liu BA; Jablonowski K; Raina M; Arce M; Pawson T; et al.
The human and mouse complement of SH2 domain proteins - Establishing the boundaries of phosphotyrosine signaling
00
150221150 2006 NEW ENGLAND JOURNAL OF MEDICINE 354 (20): 2166-2175
Yachimski PS; Chung RT; Sahani DV; Amrein PC; Misdraji J; et al.
A 46-year-old woman with sudden onset of abdominal distention - Budd-Chiari syndrome, with centrilobular hepatocellular necrosis, sinusoidal dilatation, congestion, and red-cell extravasation consistent with the presence of venous outflow obstruction. Heterozygosity for factor V Leiden. V617F mutation in JAK2.
01
#LCRNCRNode / Date / Journal / AuthorLCSGCS
151115151 2006 ONCOGENE 25 (9): 1434-1436
Lee JW; Kim YG; Soung YH; Han KJ; Kim SY; et al.
The JAK2 V617F mutation in de novo acute myelogenous leukemias
34
152119152 2006 PATHOLOGIE BIOLOGIE 54 (4): 182-184
Berger R
A recurrent mutation of the JAK2 gene in chronic myeloproliferative disorders
00
153198153 2006 PHARMACOGENOMICS 7 (4): 597-612
Ma PC; Zhang XD; Wang ZHJ
High-throughput mutational analysis of the human cancer genome
00
154736154 2006 PLOS MEDICINE 3 (7): Art. No. E270
Pikman Y; Lee BH; Mercher T; McDowell E; Ebert BL; et al.
MPLW515L is anovel somatic activating mutation in myelofibrosis with myeloid metaplasia
00
155439155 2006 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 103 (16): 6224-6229
Jamieson CHM; Gotlib J; Durocher JA; Chao MP; Mariappan MR; et al.
The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation
22
156847156 2006 REVUE DE MEDECINE INTERNE 27 (6): 473-477
Marie I; Herve F
Mutation of protein kinase JAK2 in polycythemia vera: new perspectives in physiopathology and therapy
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15725185157 2006 SEMINARS IN THROMBOSIS AND HEMOSTASIS 32 (3): 174-207
Michiels JJ; Berneman Z; Van Bockstaele D; van der Planken M; De Raeve H; et al.
Clinical and laboratory features, pathobiology of platelet-mediated thrombosis and bleeding complications, and the molecular etiology of essential thrombocythemia and polycythemia vera: Therapeutic implications
23
158243158 2006 SEMINARS IN THROMBOSIS AND HEMOSTASIS 32 (3): 208-218
Briere JB
Budd-Chiari syndrome and portal vein thrombosis associated with myeloproliferative disorders: Diagnosis and management
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15911148159 2006 SEMINARS IN THROMBOSIS AND HEMOSTASIS 32 (3): 219-230
Thiele J; Kvasnicka HM
Clinicopathological criteria for differential diagnosis of thrombocythemias in various myeloproliferative disorders
01
160342160 2006 SEMINARS IN THROMBOSIS AND HEMOSTASIS 32 (3): 246-250
Mossuz P
Influence of the assays of endogenous colony formation and serum erythropoietin on the diagnosis of polycythemia vera and essential thrombocythemia
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#LCRNCRNode / Date / Journal / AuthorLCSGCS
161474161 2006 SEMINARS IN THROMBOSIS AND HEMOSTASIS 32 (3): 251-259
Landolfi R; Di Gennaro L; Novarese L; Patrono C
Aspirin for the control of platelet activation and prevention of thrombosis in essential thrombocythemia and polycythemia vera: Current insights and rationale for future studies
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162251162 2006 SEMINARS IN THROMBOSIS AND HEMOSTASIS 32 (3): 267-275
Lengfelder E; Merx K; Hehlmann R
Diagnosis and therapy of polycythemia vera
00
163235163 2006 SEMINARS IN THROMBOSIS AND HEMOSTASIS 32 (3): 283-288
Harrison CN
Management of essential thrombocythemia: Implications of the Medical Research Council Primary Thrombocythemia 1 trial
01
16419229164 2006 SEMINARS IN THROMBOSIS AND HEMOSTASIS 32 (4): 307-340
Michiels JJ; De Raeve H; Berneman Z; Van Bockstaele D; Hebeda K; et al.
The 2001 World Health Organization and updated European clinical and pathological criteria for the diagnosis, classification, and staging of the Philadelphia chromosome-negative chronic myeloproliferative disorders
00
1652669165 2006 SEMINARS IN THROMBOSIS AND HEMOSTASIS 32 (4): 341-351
Villeval JL; James C; Pisani DF; Casadevall N; Vainchenker W
New insights into the pathogenesis of JAK2 V617F-positive myeloproliferative disorders and consequences for the management of patients
00
16611129166 2006 SEMINARS IN THROMBOSIS AND HEMOSTASIS 32 (4): 381-398
Bellucci S; Michiels JJ
The role of JAK2 V617F mutation, spontaneous erythropoiesis and megakaryocytopoiesis, hypersensitive platelets, activated leukocytes, and endothelial cells in the etiology of thrombotic manifestations in polycythemia vera and essential thrombocythemia
00
167341167 2006 SEMINARS IN THROMBOSIS AND HEMOSTASIS 32 (4): 417-421
Kiladjian JJ; Rain JD; Bernard JF; Briere J; Chomienne C; et al.
Long-term incidence of hematological evolution in three french prospective studies of hydroxyurea and pipobroman in polycythemia vera and essential thrombocythemia
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168238168 2006 SEMINARS IN THROMBOSIS AND HEMOSTASIS 32 (4): 430-436
Gisslinger H
Update on diagnosis and management of essential thrombocythemia
00
169160169 2006 TRANSFUSION MEDICINE AND HEMOTHERAPY 33 (3): 217-226
Gnatenko DV; Bahou WF
Recent advances in platelet transcriptomics
01

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