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Tue Oct 5 15:53:35 2004
The open pore conformation of potassium channels
Jiang YX, Lee A, Chen JY, Cadene M, Chait BT, MacKinnon R
NATURE 417 (6888): 523-526 MAY 30 2002
and the citing papers

Nodes: 228, Authors: 631, Journals: 83, Outer References: 6730, Words: 768
Collection span: 2002 - 2004
View: Overview. Sorted by year, source, volume, issue, page.
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
11331 2002 BIOCHEMISTRY 41(35):10771-10777
Valiyaveetil FI; Zhou YF; Mackinnon R
Lipids in the structure, folding, and function of the KcsA K+ channel
629
22372 2002 BIOCHEMISTRY 41(46):13653-13662
Irizarry SN; Kutluay E; Drews G; Hart SJ; Heginbotham L
Opening the KcsA K+ channel: Tryptophan scanning and complementation analysis lead to mutants with altered gating
59
321103 2002 BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1565(2):294-307
Sansom MSP; Shrivastava IH; Bright JN; Tate J; Capener CE; Biggin PC
Potassium channels: structures, models, simulations
1123
42564 2002 BIOPHYSICAL JOURNAL 83(4):1867-1876
Biggin PC; Sansom MSP
Open-state models of a potassium channel
610
51505 2002 BIOPHYSICAL JOURNAL 83(6):3607-3618
Guerrero G; Siegel MS; Roska B; Loots E; Isacoff EY
Tuning FlaSh: Redesign of the dynamics, voltage range, and color of the genetically encoded optical sensor of membrane potential
16
61266 2002 CELL 111(2):231-239
Yifrach O; MacKinnon R
Energetics of pore opening in a voltage-gated K+ channel
2230
74607 2002 CELL 111(7):957-965
Nishida M; MacKinnon R
Structural basis of inward rectification: Cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 angstrom resolution
1753
82158 2002 CURRENT BIOLOGY 12(16):R566-R568
Sansom MSP; Capener CE
Ion channels: Open at last
00
92539 2002 CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT 5(5):741-748
Madden DR
The inner workings of the AMPA receptors
14
1027410 2002 HUMAN MOLECULAR GENETICS 11(20):2425-2433
Capener CE; Kim HJ; Arinaminpathy Y; Sansom MSP
Ion channels: structural bioinformatics and modelling
46
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
1117111 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(38):35393-35401
Yarov-Yarovoy V; McPhee JC; Idsvoog D; Pate C; Scheuer T; Catterall WA
Role of amino acid residues in transmembrane segments IS6 and IIS6 of the Na+ channel alpha subunit in voltage-dependent gating and drug block
614
1227012 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(42):39880-39886
Tang YJ; Zaitseva F; Lamb RA; Pinto LH
The gate of the influenza virus M-2 proton channel is formed by a single tryptophan residue
018
1314913 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(46):43997-44004
Babenko AP; Bryan J
SUR-dependent modulation of K-ATP channels by an N-terminal K(IR)6.2 peptide - Defining intersubunit gating interactions
04
1423814 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(50):48289-48294
Guo Y; Waldron GJ; Murrell-Lagnado R
A role for the middle C terminus of G-protein-activated inward rectifier potassium channels in regulating gating
13
1514115 2002 JOURNAL OF CELL BIOLOGY 159(2):349-359
Skerrett IM; Aronowitz J; Shin JH; Cymes G; Kasperek E; Cao FL; Nicholson BJ
Identification of amino acid residues lining the pore of a gap junction channel
016
1625216 2002 JOURNAL OF GENERAL PHYSIOLOGY 120(1):99-116
Simoes M; Garneau L; Klein H; Banderali U; Hobeila F; Roux B; Parent L; Sauve R
Cysteine mutagenesis and computer modeling of the S6 region of an intermediate conductance IKCa channel
13
1723417 2002 JOURNAL OF GENERAL PHYSIOLOGY 120(3):323-335
Nimigean CM; Miller C
Na+ block and permeation in a K+ channel of known structure
513
1814418 2002 JOURNAL OF GENERAL PHYSIOLOGY 120(4):455-463
Gandhi CS; Isacoff EY
Perspective - Molecular models of voltage sensing
821
1913919 2002 JOURNAL OF GENERAL PHYSIOLOGY 120(4):465-473
Bezanilla F
Perspective - Voltage sensor movements
920
2044220 2002 JOURNAL OF GENERAL PHYSIOLOGY 120(4):475-481
Larsson HP
Perspective - The search is on for the voltage sensor-to-gate coupling
37
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
2113921 2002 JOURNAL OF GENERAL PHYSIOLOGY 120(5):647-662
Zhou Z; Hu SH; Hwang TC
Probing an open CFTR pore with organic anion blockers
09
2227222 2002 JOURNAL OF GENERAL PHYSIOLOGY 120(5):663-676
Lu Z; Klem AM; Ramu Y
Coupling between voltage sensors and activation gate in voltage-gated K+ channels
1118
2327123 2002 JOURNAL OF GENERAL PHYSIOLOGY 120(6):829-843
Qian X; Nimigean CM; Niu XW; Moss BL; Magleby KL
Slo1 tail domains, but not the Ca2+ bowl, are required for the beta 1 subunit to increase the apparent Ca2+ sensitivity of BK channels
15
2418224 2002 JOURNAL OF MOLECULAR BIOLOGY 322(4):851-869
Im W; Roux B
Ion permeation and selectivity of OmpF porin: A theoretical study based on molecular dynamics, brownian dynamics, and continuum electrodiffusion theory
522
2525425 2002 JOURNAL OF NEUROSCIENCE 22(21):9331-9339
Helton TD; Kojetin DJ; Cavanagh J; Horne WA
Alternative splicing of a beta(4) subunit proline-rich motif regulates voltage-dependent gating and toxin block of Ca(v)2.1 Ca2+ channels
01
2625926 2002 MOLECULAR CELL 10(3):469-481
Jin TH; Peng LY; Mirshahi T; Rohacs T; Chan KW; Sanchez R; Logothetis DE
The beta gamma subunits of G proteins gate a K+ channel by pivoted bending of a transmembrane segment
1525
272827 2002 NATURE 417(6888):501-502
Schumacher M; Adelman JP
Ion channels - An open and shut case
12
2814128 2002 NATURE 417(6888):515-522
Jiang YX; Lee A; Chen JY; Cadene M; Chait BT; MacKinnon R
Crystal structure and mechanism of a calcium-gated potassium channel
128229
2913029 2002 NATURE 417(6888):523-526
Jiang YX; Lee A; Chen JY; Cadene M; Chait BT; MacKinnon R
The open pore conformation of potassium channels
227227
3028130 2002 NATURE 419(6902):35-42
Yellen G
The voltage-gated potassium channels and their relatives
1955
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
3113031 2002 NATURE 419(6908):715-718
Iyer R; Iverson TM; Accardi A; Miller C
A biological role for prokaryotic ClC chloride channels
326
322232 2002 NATURE REVIEWS MOLECULAR CELL BIOLOGY 3(7):469-469
[Anon]
Structure watch - ... and the pore
00
3323333 2002 PHYSIOLOGY & BEHAVIOR 77(4-5):577-582
Qian A; Johnson JW
Channel gating of NMDA receptors
22
3423434 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(19):12461-12466
Chen J; Seebohm G; Sanguinetti MC
Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels
920
3521535 2002 SCIENCE 298(5598):1562-1563
Bezanilla F; Perozo E
Force and voltage sensors in one structure
02
3625536 2002 SCIENCE 298(5598):1582-1587
Bass RB; Strop P; Barclay M; Rees DC
Crystal structure of Escherichia coli MscS, a voltage-modulated and mechanosensitive channel
2059
3731237 2002 SCIENTIST 16(15):23-24
Johnston J
Bit by bit, the structure of the potassium ion channel emerges
00
3821138 2002 STRUCTURE 10(8):1027-1029
Perozo E
New structural perspectives on K+ channel gating
27
39122939 2003 ADVANCES IN MICROBIAL PHYSIOLOGY, VOL 47 47:187-254
Berks BC; Palmer T; Sargent F
The Tat protein translocation pathway and its role in microbial physiology
08
4064140 2003 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 285(4):C788-C796
Harris T; Graber AR; Covarrubias M
Allosteric modulation of a neuronal K+ channel by 1-alkanols is linked to a key residue in the activation gate
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
4171841 2003 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 42(46):5671-5675
Trauner D
Potassium channels: Symmetric, selective, and sensitive
00
42214542 2003 ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY 19:23-44
Matulef K; Zagotta WN
Cyclic nucleotide-gated ion channels
05
4313643 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 303(1):238-246
Massilia GR; Eliseo T; Grolleau F; Lapied B; Barbier J; Bournaud R; Molgo J; Cicero DO; Paci M; Schinina ME; Ascenzi P; Polticelli F
Contryphan-Vn: a modulator of Ca2+-dependent K+ channels
07
4461744 2003 BIOCHEMISTRY 42(31):9263-9268
Nimigean CM; Chappie JS; Miller C
Electrostatic tuning of ion conductance in potassium channels
39
45106945 2003 BIOCHEMISTRY 42(34):10045-10053
Booth IR; Edwards MD; Miller S
Bacterial ion channels
18
4649646 2003 BIOCHEMISTRY 42(46):13646-13658
Hwang TC; Koeppe RE; Andersen OS
Genistein can modulate channel function by a phosphorylation-independent mechanism: Importance of hydrophobic mismatch and bilayer mechanics
06
4712747 2003 BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1609(1):55-62
Wu CH; Vasilets LA; Takeda K; Kawamura M; Schwarz W
Functional role of the N-terminus of Na+,K+-ATPase alpha-subunit as an inactivation gate of palytoxin-induced pump channel
01
48221948 2003 BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1612(1):1-40
Lee AG
Lipid-protein interactions in biological membranes: a structural perspective
024
4935349 2003 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1652(1):35-51
Luzhkov VB; Nilsson J; Arhem P; Aqvist J
Computational modelling of the open-state K(v)1.5 ion channel block by bupivacaine
00
5032650 2003 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 13(10):1829-1835
Pearlstein RA; Vaz RJ; Kang JS; Chen XL; Preobrazhenskaya M; Shchekotikhin AE; Korolev AM; Lysenkova LN; Miroshnikova OV; Hendrix J; Rampe D
Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches
27
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
51310851 2003 BIOPHYSICAL JOURNAL 84(1):14-27
Law RJ; Tieleman DP; Sansom MSP
Pores formed by the nicotinic receptor M2 delta peptide: A molecular dynamics simulation study
03
5224752 2003 BIOPHYSICAL JOURNAL 84(1):295-305
Ding SH; Horn R
Effect of S6 tail mutations on charge movement in shaker potassium channels
02
5322453 2003 BIOPHYSICAL JOURNAL 84(2):910-921
Sackin H; Vasilyev A; Palmer LG; Krambis M
Permeant cations and blockers modulate pH gating of ROMK channels
13
5435254 2003 BIOPHYSICAL JOURNAL 84(4):2345-2356
Capener CE; Proks P; Ashcroft FM; Sansom MSP
Filter flexibility in a mammalian K channel: Models and simulations of Kir6.2 mutants
69
5518055 2003 BIOPHYSICAL JOURNAL 84(5):2814-2830
Garafoli S; Jordan PC
Modeling permeation energetics in the KcsA potassium channel
11
5624156 2003 BIOPHYSICAL JOURNAL 84(5):2929-2942
Shealy RT; Murphy AD; Ramarathnam R; Jakobsson E; Subramaniam S
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14
5726157 2003 BIOPHYSICAL JOURNAL 84(5):2969-2980
Avdonin V; Tang XD; Hoshi T
Stimulatory action of internal protons on Slo1 BK channels
04
5824858 2003 BIOPHYSICAL JOURNAL 84(5):3022-3036
Zhang M; Korolkova YV; Liu J; Jiang M; Grishin EV; Tseng GN
BeKm-1 is a HERG-specific toxin that shares the structure with ChTx but the mechanism of action with ErgTx1
29
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Alagem N; Yesylevskyy S; Reuveny E
The pore helix is involved in stabilizing the open state of inwardly rectifying K+ channels
35
6022660 2003 BIOPHYSICAL JOURNAL 85(2):911-920
Wang SY; Bonner K; Russell C; Wang GK
Tryptophan scanning of D1S6 and D4S6 C-termini in voltage-gated sodium channels
05
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
6156261 2003 BIOPHYSICAL JOURNAL 85(5):2787-2800
Domene C; Sansom MSP
Potassium channel, ions, and water: Simulation studies based on the high resolution X-ray structure of KcsA
13
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Im W; Feig M; Brooks CL
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07
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Clapham DE
Symmetry, selectivity, and the 2003 Nobel Prize
01
6423364 2003 CELL BIOCHEMISTRY AND BIOPHYSICS 39(3):183-193
Bett GCL; Rasmusson RL
Functionally-distinct proton-binding in HERG suggests the presence of two binding sites
01
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Williamson IM; Alvis SJ; East JM; Lee AG
The potassium channel KcsA and its interaction with the lipid bilayer
02
6626966 2003 CURRENT OPINION IN CHEMICAL BIOLOGY 7(1):150-156
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Molecular modeling of ion channels: structural predictions
24
6745867 2003 CURRENT OPINION IN CHEMICAL BIOLOGY 7(6):741-748
Discher BM; Koder RL; Moser CC; Dutton PL
Hydrophillic to amphiphilic design in redox protein maquettes
02
68138168 2003 CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT 6(5):611-619
Domene C; Haider S; Sansom MS
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11
6976369 2003 CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT 6(5):667-674
Mitcheson JS; Perry MD
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11
7022870 2003 CURRENT OPINION IN NEUROBIOLOGY 13(3):279-283
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04
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
7165071 2003 CURRENT OPINION IN STRUCTURAL BIOLOGY 13(4):412-417
Curran AR; Engelman DM
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07
7271472 2003 CURRENT SCIENCE 85(7):850-852
Mathew MK
A molecular voltmeter: Solution to a fifty-year-old puzzle?
00
7314273 2003 EMBO JOURNAL 22(1):36-46
Miller S; Bartlett W; Chandrasekaran S; Simpson S; Edwards M; Booth IR
Domain organization of the MscS mechanosensitive channel of Escherichia coli
18
7432574 2003 EMBO JOURNAL 22(16):4049-4058
Kuo MMC; Saimi Y; Kung C
Gain-of-function mutations indicate that Escherichia coli Kch forms a functional K+ conduit in vivo
12
7512675 2003 EMBO REPORTS 4(1):70-75
Proks P; Antcliff JF; Ashcroft FM
The ligand-sensitive gate of a potassium channel lies close to the selectivity filter
68
7622376 2003 FEBS LETTERS 541(1-3):28-32
Demmers JAA; van Dalen A; de Kruijff B; Heck AJR; Killian JA
Interaction of the K+ channel KcsA with membrane phospholipids as studied by ESI mass spectrometry
09
7743177 2003 FEBS LETTERS 547(1-3):20-26
Milnes JT; Dempsey CE; Ridley JM; Crociani O; Arcangeli A; Hancox JC; Witchel HJ
Preferential closed channel blockade of HERG potassium currents by chemically synthesised BeKm-1 scorpion toxin
02
7812178 2003 FEBS LETTERS 552(1):12-16
Gazzarrini S; Severino M; Lombardi M; Morandi M; DiFrancesco D; Van Etten JL; Thiel G; Moroni A
The viral potassium channel Kcv: structural and functional features
13
7955679 2003 FEBS LETTERS 553(3):321-327
Arinaminpathy Y; Biggin PC; Shrivastava IH; Sansom MSP
A prokaryotic glutamate receptor: homology modelling and molecular dynamics simulations of GluR0
00
8062680 2003 FEBS LETTERS 555(1):62-65
MacKinnon R
Potassium channels
311
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
8176681 2003 FEBS LETTERS 555(1):85-90
Beckstein O; Biggin PC; Bond P; Bright JN; Domene C; Grottesi A; Holyoake J; Sansom MSP
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15
8254182 2003 FEBS LETTERS 555(1):111-115
Bass RB; Locher KP; Borths E; Poon Y; Strop P; Lee A; Rees DC
The structures of BtuCD and MscS and their implications for transporter and channel function
02
83210283 2003 FRONTIERS IN BIOSCIENCE 8:D1055-D1071
Delcour AH
Solute uptake through general porins
05
8448184 2003 FRONTIERS IN BIOSCIENCE 8:S1356-S1370
Sapronova A; Bystrov VS; Green ME
Water, proton transfer, and hydrogen bonding in ion channel gating
01
85513485 2003 JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 35(6):461-475
Jones SW
Calcium channels: Unanswered questions
00
8617186 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(12):10675-10682
Cronin NB; O'Reilly A; Duclohier H; Wallace BA
Binding of the anticonvulsant drug lamotrigine and the neurotoxin batrachotoxin to voltage-gated sodium channels induces conformational changes associated with block and steady-state activation
03
8725987 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(19):16551-16560
Uchida K; Miyauchi H; Furuichi T; Michikawa T; Mikoshiba K
Critical regions for activation gating of the inositol 1,4,5-trisphosphate receptor
18
8844888 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(31):29079-29085
Neale EJ; Elliott DJS; Hunter M; Sivaprasadarao A
Evidence for intersubunit interactions between S4 and S5 transmembrane segments of the Shaker potassium channel
18
8925989 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(36):34533-34540
Peng CH; Rich ED; Varnum MD
Achromatopsia-associated mutation in the human cone photoreceptor cyclic nucleotide-gated channel CNGB3 subunit alters the ligand sensitivity and pore properties of heteromeric channels
15
9013690 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(46):45528-45538
Anyatonwu GI; Buck ED; Ehrlich BE
Methanethiosulfonate ethylammonium block of amine currents through the ryanodine receptor reveals single pore architecture
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
9115291 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(50):50128-50135
Zhang W; Bogdanov M; Pi J; Pittard AJ; Dowhan W
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05
9264492 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(50):50654-50663
Claydon TW; Makary SY; Dibb KM; Boyett MR
The selectivity filter may act as the agonist-activated gate in the G protein-activated Kir3.1/Kir3.4 K+ channel
00
9362793 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(50):50724-50731
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12
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00
9614996 2003 JOURNAL OF GENERAL PHYSIOLOGY 121(2):125-148
Xia XM; Ding JP; Lingle CJ
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00
9726797 2003 JOURNAL OF GENERAL PHYSIOLOGY 121(2):163-175
Sheets MF; Hanck DA
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03
9848698 2003 JOURNAL OF GENERAL PHYSIOLOGY 121(5):375-397
Park JB; Kim HJ; Ryu PD; Moczydlowski E
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12
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Flynn GE; Zagotta WN
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01
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
101964101 2003 JOURNAL OF GENERAL PHYSIOLOGY 122(5):541-556
Sukhareva M; Hackos DH; Swartz K
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24
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Phillips LR; Nichols CG
Ligand-induced closure of inward rectifier Kir6.2 channels traps spermine in the pore
03
103322103 2003 JOURNAL OF MEDICINAL CHEMISTRY 46(11):2017-2022
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Sapronova A; Bystrov V; Green ME
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sup-9, sup-10, and unc-93 may encode components of a two-pore K+ channel that coordinates muscle contraction in Caenorhabditis elegans
00
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111231111 2003 JOURNAL OF PEPTIDE SCIENCE 9(11-12):769-775
O'Reilly AO; Wallace BA
The peptaibol antiamoebin as a model ion channel: Similarities to bacterial potassium channels
00
112279112 2003 JOURNAL OF PHYSICAL CHEMISTRY B 107(2):627-636
Bright JN; Sansom MSP
The flexing/twirling helix: Exploring the flexibility about molecular hinges formed by proline and glycine motifs in transmembrane helices
04
113124113 2003 JOURNAL OF PHYSIOLOGY-LONDON 548(2):353-360
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C-terminal interaction of KCNQ2 and KCNQ3 K+ channels
03
114235114 2003 JOURNAL OF PHYSIOLOGY-LONDON 548(3):667-675
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Veratridine block of rat skeletal muscle Nav1.4 sodium channels in the inner vestibule
13
115142115 2003 JOURNAL OF PHYSIOLOGY-LONDON 549(1):107-120
Thompson J; Begenisich T
Functional identification of ion binding sites at the internal end of the pore in Shaker K+ channels
01
116153116 2003 JOURNAL OF PHYSIOLOGY-LONDON 549(3):683-695
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C-type inactivation involves a significant decrease in the intracellular aqueous pore volume of Kv1.4 K+ channels expressed in Xenopus oocytes
04
117298117 2003 MEMBRANE PROTEINS 63:177-209
Strop P; Bass R; Rees DC
Prokaryotic mechanosensitive channels
25
118270118 2003 MEMBRANE PROTEINS 63:211-241
Bezanilla F; Perozo E
The voltage sensor and the gate in ion channels
14
119250119 2003 MOLECULAR PHARMACOLOGY 63(3):499-511
Lipkind GM; Fozzard HA
Molecular modeling of interactions of dihydropyridines and phenylalkylamines with the inner pore of the L-type Ca2+ channel
11
120315120 2003 MOLECULAR PHARMACOLOGY 63(6):1199-1201
Johnson JW
Acid tests of N-methyl-D-aspartate receptor gating basics
00
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121353121 2003 MOLECULAR PHARMACOLOGY 63(6):1212-1222
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27
122229122 2003 MOLECULAR PHARMACOLOGY 63(6):1398-1406
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Point mutations at L1280 in Na(v)1.4 channel D3-S6 modulate binding affinity and stereoselectivity of bupivacaine enantiomers
01
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