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Nodes: 206,
Authors: 782,
Journals: 102,
Outer References: 5771,
Words: 773
Collection span: 2003 - 2005
View: Overview. Sorted by year, source, volume, issue, page.
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 1 | 2 | 71 | 1 2003 CELL 115 (2): 199-208 Schwarz DS; Hutvagner G; Du T; Xu ZS; Aronin N; et al. Asymmetry in the assembly of the RNAi enzyme complex | 54 | 158 |
| 2 | 2 | 29 | 2 2003 CELL 115 (2): 209-216 Khvorova A; Reynolds A; Jayasena SD Functional siRNAs and rniRNAs exhibit strand bias | 43 | 123 |
| 3 | 1 | 48 | 3 2003 CHEMBIOCHEM 4 (10): 928-935 Achenbach TV; Brunner B; Heermeier K Oligonucleotide-based knockdown technologies: Antisense versus RNA interference | 0 | 3 |
| 4 | 1 | 105 | 4 2003 CHEMBIOCHEM 4 (10): 1033-1039 Conklin DS RNA-interference-based silencing of mammalian gene expression | 0 | 2 |
| 5 | 1 | 59 | 5 2003 CHEMBIOCHEM 4 (11): 1129-1136 Arendt CW; Tang GL; Zilberstein A Vector systems for the delivery of small interfering RNAs: Managing the RISC | 0 | 0 |
| 6 | 1 | 60 | 6 2003 CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT 6 (4): 561-569 Lavery KS; King TH Antisense and RNAi: Powerful tools in drug target discovery and validation | 4 | 14 |
| 7 | 1 | 8 | 7 2003 GENE THERAPY 10 (23): 1931-1932 Kolfschoten I; Agami R RNA interference gene therapy - Allelic gene inactivation: pinpointing the problem | 0 | 1 |
| 8 | 1 | 4 | 8 2003 GENETIC ENGINEERING NEWS 23 (16): 32-32 Dorris D; Wardlaw S Designing optimized small interfering RNAs - Assay tutorial: siRNA-Design algorithm determines susceptibility to RNA interference for target identification | 0 | 0 |
| 9 | 1 | 43 | 9 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (45): 44312-44319 Saxena S; Jonsson ZO; Dutta A Small RNAs with imperfect match to endogenous mRNA repress translation - Implications for off-target activity of small inhibitory RNA in mammalian cells | 19 | 34 |
| 10 | 1 | 53 | 10 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (48): 47724-47730 Sommer U; Liu H; Doering TL An alpha-1,3-mannosyltransferase of Cryptococcus neoformans | 0 | 5 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 11 | 1 | 72 | 11 2003 JOURNAL OF BIOMEDICAL SCIENCE 10 (6): 607-616 Haasnoot J; Cupac D; Berkhout B Inhibition of virus replication by RNA interference | 1 | 4 |
| 12 | 1 | 38 | 12 2003 LANCET 362 (9393): 1401-1403 Wall NR; Shi Y Small RNA: can RNA interference be exploited for therapy? | 5 | 38 |
| 13 | 1 | 174 | 13 2003 LETTERS IN PEPTIDE SCIENCE 10 (3-4): 361-372 Azorsa DO; Mousses S; Caplen NJ Gene silencing through RNA interference: Potential for therapeutics and functional genomics | 0 | 0 |
| 14 | 1 | 12 | 14 2003 LETTERS IN PEPTIDE SCIENCE 10 (5-6): 437-445 Khanna S; Warnasuriya GD; Downward J; Naaby-Hansen S RNAi and 2DE, a promising combination for analysis of phospho-signalling and substrate identification | 0 | 0 |
| 15 | 1 | 35 | 15 2003 MOLECULAR CANCER RESEARCH 1 (12): 882-891 Michael MZ; O'Connor SM; Pellekaan NGV; Young GP; James RJ Reduced accumulation of specific microRNAs in colorectal neoplasia | 5 | 28 |
| 16 | 1 | 64 | 16 2003 MOLECULAR CELL 12 (3): 627-637 Aza-Blanc P; Cooper CL; Wagner K; Batalov S; Deveraux QL; et al. Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening | 18 | 49 |
| 17 | 1 | 15 | 17 2003 NATURE 425 (6953): 10-12 Check E Gene regulation: RNA to the rescue? | 2 | 9 |
| 18 | 0 | 8 | 18 2003 NATURE BIOTECHNOLOGY 21 (6): 635-637 Jackson AL; Bartz SR; Schelter J; Kobayashi SV; Burchard J; et al. Expression profiling reveals off-target gene regulation by RNAi | 205 | 205 |
| 19 | 3 | 100 | 19 2003 NATURE BIOTECHNOLOGY 21 (12): 1457-1465 Scherer LJ; Rossi JJ Approaches for the sequence-specific knockdown of mRNA | 11 | 43 |
| 20 | 1 | 41 | 20 2003 NATURE BIOTECHNOLOGY 21 (12): 1473-1479 Zeytun A; Jeromin A; Scalettar BA; Waldo GS; Bradbury ARM Fluorobodies combine GFP fluorescence with the binding characteristics of antibodies | 0 | 12 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 21 | 1 | 73 | 21 2003 NATURE REVIEWS CANCER 3 (10): 781-789 Brummelkamp TR; Bernards R Innovation - New tools for functional mammalian cancer genetics | 5 | 17 |
| 22 | 1 | 68 | 22 2003 NATURE REVIEWS DRUG DISCOVERY 2 (10): 831-838 Lindsay MA Innovation - Target discovery | 2 | 25 |
| 23 | 1 | 2 | 23 2003 NATURE REVIEWS GENETICS 4 (7): 487-487 Flintoft L A matter of trust | 0 | 0 |
| 24 | 1 | 26 | 24 2003 NUCLEIC ACIDS RESEARCH 31 (22): 6444-6449 Pusch O; Boden D; Silbermann R; Lee F; Tucker L; et al. Nucleotide sequence homology requirements of HIV-1-specific short hairpin RNA | 6 | 10 |
| 25 | 1 | 33 | 25 2003 OLIGONUCLEOTIDES 13 (5): 313-324 Lou TF; Gray CW; Gray DM The reduction of Raf-1 protein by phosphorothioate ODNs and siRNAs targeted to the same two mRNA sequences | 0 | 1 |
| 26 | 1 | 43 | 26 2003 PLANT JOURNAL 36 (1): 114-121 Lawrence RJ; Pikaard CS Transgene-induced RNA interference: a strategy for overcoming gene redundancy in polyploids to generate loss-of-function mutations | 0 | 11 |
| 27 | 1 | 83 | 27 2003 PLANT JOURNAL 36 (6): 905-917 Ekengren SK; Liu YL; Schiff M; Dinesh-Kumar SP; Martin GB Two MAPK cascades, NPR1, and TGA transcription factors play a role in Pto-mediated disease resistance in tomato | 0 | 14 |
| 28 | 1 | 94 | 28 2003 TRENDS IN MOLECULAR MEDICINE 9 (9): 397-403 Lieberman J; Song E; Lee SK; Shankar P Interfering with disease: opportunities and roadblocks to harnessing RNA interference | 4 | 14 |
| 29 | 5 | 79 | 29 2004 ACTA BIOCHIMICA POLONICA 51 (2): 431-444 Nawrot B Targeting BACE with small inhibitory nucleic acids - a future for Alzheimer's disease therapy? | 0 | 0 |
| 30 | 1 | 82 | 30 2004 ANNALS OF HEMATOLOGY 83 (1): 1-8 Scherr M; Steinmann D; Eder M RNA interference (RNAi) in hematology | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 31 | 8 | 117 | 31 2004 ANNALS OF MEDICINE 36 (7): 540-551 Barik S Development of gene-specific double-stranded RNA drugs | 0 | 0 |
| 32 | 3 | 79 | 32 2004 ARTHRITIS RESEARCH & THERAPY 6 (2): 78-85 Rutz S; Scheffold A Towards in vivo application of RNA interference - new toys, old problems | 0 | 1 |
| 33 | 1 | 41 | 33 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 317 (4): 1037-1044 Chen SJ; Wang G; Makrigiorgos GM; Price BD Stable siRNA-mediated silencing of ATM alters the transcriptional profile of HeLa cells | 0 | 0 |
| 34 | 1 | 39 | 34 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 318 (1): 289-296 Imamura T; Kanai F; Kawakami T; Amarsanaa J; Ijichi H; et al. Proteomic analysis of the TGF-beta signaling pathway in pancreatic carcinoma cells using stable RNA interference to silence Smad4 expression | 1 | 1 |
| 35 | 4 | 48 | 35 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 319 (1): 256-263 Snove O; Holen T Many commonly used siRNAs risk off-target activity | 4 | 10 |
| 36 | 5 | 42 | 36 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 319 (1): 264-274 Chalk AM; Wahlestedt C; Sonnhammer ELL Improved and automated prediction of effective siRNA | 3 | 6 |
| 37 | 6 | 40 | 37 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 321 (1): 247-253 Saetrom P; Snove O A comparison of SiRNA efficacy predictors | 2 | 2 |
| 38 | 12 | 41 | 38 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 325 (3): 769-773 Snove O; Nedland M; Fjeldstad SH; Humberset H; Birkeland OR; et al. Designing effective siRNAs with off target control | 0 | 0 |
| 39 | 4 | 72 | 39 2004 BIOCHEMICAL JOURNAL 380: 593-603 Medema RH Optimizing RNA interference for application in mammalian cells | 1 | 4 |
| 40 | 1 | 32 | 40 2004 BIOCHEMICAL JOURNAL 380: 611-616 Rangarajan S; Raj MLS; Hernandez JM; Grotewold E; Gopalan V RNase P as a tool for disruption of gene expression in maize cells | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 41 | 2 | 39 | 41 2004 BIOCHEMISTRY 43 (7): 1921-1927 Liu YH; Braasch DA; Nulf CJ; Corey DR Efficient and isoform-selective inhibition of cellular gene expression by peptide nucleic acids | 1 | 7 |
| 42 | 1 | 9 | 42 2004 BIOINFORMATICS 20 (3): 430-432 Levenkova N; Gu QJ; Rux JJ Gene specific siRNA selector | 3 | 3 |
| 43 | 1 | 23 | 43 2004 BIOLOGICAL PSYCHIATRY 55 (8): 785-788 Carter DA Comprehensive strategies to study neuronal function in transgenic animal models | 0 | 0 |
| 44 | 1 | 28 | 44 2004 BIOTECHNIQUES 36 (1): 74-+ Kojima SI; Vignjevic D; Borisy GG Improved silencing vector co-expressing GFP and small hairpin RNA | 0 | 2 |
| 45 | 5 | 34 | 45 2004 BIOTECHNIQUES 36 (4): 557-+ Scherer L; Rossi JJ RNAi applications in mammalian cells | 1 | 2 |
| 46 | 2 | 51 | 46 2004 BIOTECHNOLOGY AND BIOENGINEERING 88 (1): 121-132 Raab RM; Stephanopoulos G Dynamics of gene silencing by RNA interference | 0 | 0 |
| 47 | 1 | 33 | 47 2004 BIOTECHNOLOGY AND BIOENGINEERING 88 (7): 901-908 Mori K; Kuni-Karnochi R; Yarnane-Ohnuki N; Wakitani M; Yamano K; et al. Engineering Chinese hamster ovary cells to maximize effector function of produced antibodies using FUT8 siRNA | 0 | 0 |
| 48 | 1 | 74 | 48 2004 BLOOD 104 (4): 923-932 Ebert BL; Golub TR Genomic approaches to hematologic malignancies | 0 | 1 |
| 49 | 1 | 55 | 49 2004 BMC CANCER 4: Art. No. 44 Martinez N; Drescher B; Riehle H; Cullmann C; Vornlocher HP; et al. The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells | 0 | 2 |
| 50 | 2 | 30 | 50 2004 BMC MOLECULAR BIOLOGY 5: Art. No. 9 Fish RJ; Kruithof EKO Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 51 | 1 | 65 | 51 2004 CANCER RESEARCH 64 (11): 3949-3957 Chen W; Lee JW; Cho SY; Fine HA Proteasome-mediated destruction of the cyclin A/cyclin-dependent kinase 2 complex suppresses tumor cell growth in vitro and in vivo | 0 | 3 |
| 52 | 6 | 132 | 52 2004 CELL 116 (2): 281-297 Bartel DP MicroRNAs: Genomics, biogenesis, mechanism, and function | 24 | 213 |
| 53 | 1 | 53 | 53 2004 CELL DEATH AND DIFFERENTIATION 11 (8): 915-923 Chawla-Sarkar M; Bae SI; Reu FJ; Jacobs BS; Lindner DJ; et al. Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis | 0 | 2 |
| 54 | 4 | 48 | 54 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61 (16): 2113-2124 Li Y; Wasser S; Lim SG; Tan TMC Genome-wide expression profiling of RNA interference of hepatitis B virus gene expression and replication | 0 | 0 |
| 55 | 2 | 38 | 55 2004 CLINICAL CANCER RESEARCH 10 (15): 4983-4990 Nosrati M; Li S; Bagheri S; Ginzinger D; Blackburn EH; et al. Antitumor activity of systemically delivered ribozymes targeting murine telomerase RNA | 0 | 2 |
| 56 | 1 | 29 | 56 2004 COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 7 (7): 689-697 Zhang D; Baek SH; Ho A; Lee H; Jeong YS; et al. Targeted degradation of proteins by small molecules: A novel tool for functional proteomics | 0 | 0 |
| 57 | 1 | 24 | 57 2004 COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE 75 (1): 67-73 Cui WW; Ning JC; Naik UP; Duncan MK OptiRNAi, an RNAi design tool | 1 | 1 |
| 58 | 1 | 137 | 58 2004 CURRENT MOLECULAR MEDICINE 4 (5): 507-517 Fuchs U; Damm-Welk C; Borkhardt A Silencing of disease-related genes by small interfering RNAs | 0 | 0 |
| 59 | 3 | 65 | 59 2004 CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT 7 (2): 179-187 Kurreck J Antisense and RNA interference approaches to target validation in pain research | 0 | 1 |
| 60 | 5 | 64 | 60 2004 CURRENT OPINION IN GENETICS & DEVELOPMENT 14 (5): 470-476 Friedman A; Perrimon N Genome-wide high-throughput screens in functional genomics | 0 | 2 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 61 | 3 | 88 | 61 2004 CURRENT OPINION IN MOLECULAR THERAPEUTICS 6 (2): 129-135 Scherr M; Eder M RNAi in functional genomics | 1 | 1 |
| 62 | 7 | 58 | 62 2004 CURRENT OPINION IN MOLECULAR THERAPEUTICS 6 (2): 136-140 Nencioni A; Sandy P; Dillon C; Kissler S; Blume-Jensen P; et al. RNA interference for the identification of disease-associated genes | 0 | 2 |
| 63 | 5 | 58 | 63 2004 CURRENT OPINION IN MOLECULAR THERAPEUTICS 6 (2): 141-145 Berkhout B RNA interference as an antiviral approach: Targeting HIV-1 | 0 | 4 |
| 64 | 2 | 41 | 64 2004 CURRENT OPINION IN MOLECULAR THERAPEUTICS 6 (4): 373-380 Boden D; Pusch O; Ramratnam B HIV-1-specific RNA interference | 0 | 0 |
| 65 | 7 | 52 | 65 2004 CURRENT OPINION IN MOLECULAR THERAPEUTICS 6 (5): 546-550 Jones SW; Lindsay MA Overview of target validation and the impact of oligonucleotides | 0 | 0 |
| 66 | 11 | 64 | 66 2004 CURRENT OPINION IN PHARMACOLOGY 4 (5): 522-527 Jones SW; de Souza PM; Lindsay MA siRNA for gene silencing: a route to drug target discovery | 0 | 1 |
| 67 | 2 | 57 | 67 2004 CURRENT PHARMACEUTICAL BIOTECHNOLOGY 5 (4): 349-354 Heidenreich O Oncogene suppression by small interfering RNAs | 1 | 1 |
| 68 | 1 | 114 | 68 2004 CURRENT PHARMACEUTICAL BIOTECHNOLOGY 5 (4): 361-368 Poliseno L; Mercatanti A; Citti L; Rainaldi G RNA-based drugs: From RNA interference to short interfering RNAs | 0 | 0 |
| 69 | 1 | 98 | 69 2004 CURRENT PHARMACEUTICAL BIOTECHNOLOGY 5 (5): 441-450 Banan M; Puri N The ins and outs of RNAi in mammalian cells | 0 | 0 |
| 70 | 1 | 31 | 70 2004 CYTOGENETIC AND GENOME RESEARCH 105 (2-4): 363-374 Zhu J; Lum PY; Lamb J; GuhaThakurta D; Edwards SW; et al. An integrative genomics approach to the reconstruction of gene networks in segregating populations | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 71 | 2 | 78 | 71 2004 CYTOGENETIC AND GENOME RESEARCH 105 (2-4): 412-421 Prawitt D; Brixel L; Spangenberg C; Eshkind L; Heck R; et al. RNAi knock-down mice: an emerging technology for post-genomic functional genetics | 1 | 5 |
| 72 | 3 | 108 | 72 2004 CYTOGENETIC AND GENOME RESEARCH 105 (2-4): 422-434 Svoboda P Long dsRNA and silent genes strike back : RNAi in mouse oocytes and early embryos | 1 | 1 |
| 73 | 4 | 26 | 73 2004 DEVELOPMENTAL DYNAMICS 231 (3): 592-600 Rao M; Baraban JH; Rajaii F; Sockanathan S In vivo comparative study of RNAi methodologies by in ovo electroporation in the chick embryo | 0 | 0 |
| 74 | 1 | 61 | 74 2004 DRUG DISCOVERY TODAY 9 (22): 960-966 Stocks MR Intrabodies: Production and promise | 0 | 1 |
| 75 | 6 | 76 | 75 2004 DRUGS OF THE FUTURE 29 (7): 741-750 Sioud M Therapeutic potential of small interfering RNAs | 0 | 0 |
| 76 | 1 | 34 | 76 2004 EMBO REPORTS 5 (2): 183-188 Kong XC; Barzaghi P; Ruegg MA Inhibition of synapse assembly in mammalian muscle in vivo by RNA interference | 1 | 3 |
| 77 | 4 | 22 | 77 2004 ENVIRONMENTAL HEALTH PERSPECTIVES 112 (4): A210-A211 Stribinskis V; Ramos KS Decoding the riddle: The dawn of RNAi for the study of gene-gene and gene-environment interactions | 0 | 0 |
| 78 | 5 | 155 | 78 2004 EXPERIMENTAL GERONTOLOGY 39 (7): 985-998 Geley S; Muller C RNAi: ancient mechanism with a promising future | 0 | 0 |
| 79 | 3 | 100 | 79 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4 (3): 319-327 Devroe E; Silver PA Therapeutic potential of retroviral RNAi vectors | 1 | 6 |
| 80 | 3 | 57 | 80 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4 (4): 531-542 Ganju P; Hall J Potential applications of siRNA for pain therapy | 1 | 3 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 81 | 4 | 71 | 81 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4 (12): 1921-1929 Borkhardt A; Heidenreich O RNA interference as a potential tool in the treatment of leukaemia | 0 | 0 |
| 82 | 1 | 57 | 82 2004 FEBS LETTERS 560 (1-3): 210-214 Hung L; Kumar V Specific inhibition of gene expression and transactivation functions of hepatitis B virus X protein and c-myc by small interfering RNAs | 0 | 1 |
| 83 | 6 | 82 | 83 2004 GENE THERAPY 11 (16): 1241-1248 Caplen NJ Gene therapy progress and prospects. Downregulating gene expression: the impact of RNA interference | 0 | 3 |
| 84 | 2 | 44 | 84 2004 GENES & DEVELOPMENT 18 (9): 975-980 Martinez J; Tuschl T RISC is a 5 ' phosphomonoester-producing RNA endonuclease | 7 | 27 |
| 85 | 2 | 71 | 85 2004 GENES & DEVELOPMENT 18 (24): 3041-3054 Urist M; Tanaka T; Poyurovsky MV; Prives C p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2 | 0 | 0 |
| 86 | 2 | 89 | 86 2004 GENOME BIOLOGY 5 (1): Art. No. R1 Enright AJ; John B; Gaul U; Tuschl T; Sander C; et al. MicroRNA targets in Drosophila | 0 | 0 |
| 87 | 6 | 39 | 87 2004 GENOME BIOLOGY 5 (9): Art. No. 115 Lai EC Predicting and validating microRNA targets | 0 | 2 |
| 88 | 4 | 160 | 88 2004 HUMAN MOLECULAR GENETICS 13: R275-R288 Buckingham SD; Esmaeili B; Wood M; Sattelle DB RNA interference: from model organisms towards therapy for neural and neuromuscular disorders | 0 | 2 |
| 89 | 1 | 66 | 89 2004 INTERNATIONAL JOURNAL OF CANCER 112 (6): 994-1002 Wang XL; Wang MY; Amarzguioui M; Liu F; Fodstad O; et al. Downregulation of tissue factor by RNA interference in human melanoma Lox-L cells reduces pulmonary metastasis in nude mice | 0 | 0 |
| 90 | 1 | 31 | 90 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (16): 16657-16661 Huang FT; Khvorova A; Marshall W; Sorkin A Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference | 0 | 13 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 91 | 1 | 86 | 91 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (40): 41975-41984 Chang TS; Cho CS; Park S; Yu SQ; Kang SW; et al. Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria | 0 | 2 |
| 92 | 2 | 37 | 92 2004 JOURNAL OF CELL SCIENCE 117 (25): 6043-6051 Zhao XJ; McKillop-Smith S; Muller B The human histone gene expression regulator HBP/SLBP is required for histone and DNA synthesis, cell cycle progression and cell proliferation in mitotic cells | 0 | 0 |
| 93 | 2 | 57 | 93 2004 JOURNAL OF CLINICAL INVESTIGATION 114 (8): 1107-1116 Lee MD; She YH; Soskis MJ; Borella CP; Gardner JR; et al. Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics | 0 | 0 |
| 94 | 11 | 166 | 94 2004 JOURNAL OF DRUG TARGETING 12 (6): 315-340 Gilmore IR; Fox SP; Hollins AJ; Muhammad SB; Akhtar S The design and exogenous delivery of siRNA for post-transcriptional gene silencing | 0 | 0 |
| 95 | 2 | 41 | 95 2004 JOURNAL OF MOLECULAR BIOLOGY 342 (4): 1069-1076 Gibbons DL; Shashikant C; Hayday AC A comparative analysis of RNA targeting strategies in the thymosin beta 4 gene | 0 | 0 |
| 96 | 3 | 28 | 96 2004 JOURNAL OF MOLECULAR BIOLOGY 342 (4): 1077-1083 Zhang HF; Altman S Inhibition of the expression of the human RNase P protein subunits Rpp21, Rpp25, Rpp29 by external guide sequences (EGSs) and siRNA | 0 | 0 |
| 97 | 6 | 69 | 97 2004 JOURNAL OF MOLECULAR ENDOCRINOLOGY 33 (3): 545-557 Bantounas I; Phylactou LA; Uney JB RNA interference and the use of small interfering RNA to study gene function in mammalian systems | 0 | 0 |
| 98 | 1 | 66 | 98 2004 JOURNAL OF NEUROCHEMISTRY 88 (2): 257-265 Trulzsch B; Wood M Applications of nucleic acid technology in the CNS | 2 | 3 |
| 99 | 1 | 49 | 99 2004 JOURNAL OF THE NATIONAL CANCER INSTITUTE 96 (17): 1288-1299 Lovat PE; Di Sano F; Corazzari M; Fazi B; Donnorso RP; et al. Gangliosides link the acidic sphingomyelinase-mediated induction of ceramide to 12-lipoxygenase-dependent apoptosis of neuroblastoma in response to fenretinide | 0 | 2 |
| 100 | 3 | 33 | 100 2004 LANCET NEUROLOGY 3 (3): 145-149 Davidson BL; Paulson HL Molecular medicine for the brain: silencing of disease genes with RNA interference | 4 | 14 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 101 | 2 | 37 | 101 2004 MECHANISMS OF DEVELOPMENT 121 (9): 1137-1143 Nakamura H; Katahira T; Sato T; Watanabe Y; Funahashi J Gain-and loss-of-function in chick embryos by electroporation | 0 | 1 |
| 102 | 7 | 434 | 102 2004 MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS 68 (3): 432-+ Wang QQ; Carmichael GG Effects of length and location on the cellular response to double-stranded RNA | 0 | 2 |
| 103 | 2 | 99 | 103 2004 MOLECULAR PHARMACOLOGY 66 (6): 1361-1371 Blancafort P; Segal DJ; Barbas CF Designing transcription factor architectures for drug discovery | 0 | 0 |
| 104 | 1 | 50 | 104 2004 MOLECULAR THERAPY 10 (1): 162-171 Uchida H; Tanaka T; Sasaki K; Kato K; Dehari H; et al. Adenovirus-mediated transfer of siRNA against survivin induced apoptosis and attenuated tumor cell growth in vitro and in vivo | 0 | 1 |
| 105 | 1 | 30 | 105 2004 NATURE 427 (6974): 541-544 Li T; Chang CY; Jin DY; Lin PJ; Khvorova A; et al. Identification of the gene for vitamin K epoxide reductase | 0 | 15 |
| 106 | 2 | 10 | 106 2004 NATURE 428 (6981): 375-+ Fraser A RNA interference - Human genes hit the big screen | 0 | 4 |
| 107 | 3 | 30 | 107 2004 NATURE 428 (6981): 431-437 Berns K; Hijmans EM; Mullenders J; Brummelkamp TR; Velds A; et al. A large-scale RNAi screen in human cells identifies new components of the p53 pathway | 20 | 81 |
| 108 | 1 | 30 | 108 2004 NATURE 430 (6999): 569-573 Sayah DM; Sokolskaja E; Berthoux L; Luban J Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1 | 0 | 11 |
| 109 | 12 | 101 | 109 2004 NATURE 431 (7006): 371-378 Hannon GJ; Rossi JJ Unlocking the potential of the human genome with RNA interference | 4 | 22 |
| 110 | 3 | 3 | 110 2004 NATURE 432 (7014): 136-136 Check E Hopes rise for RNA therapy as mouse study hits target | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 111 | 2 | 22 | 111 2004 NATURE 432 (7014): 173-178 Soutschek J; Akinc A; Bramlage B; Charisse K; Constien R; et al. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs | 4 | 19 |
| 112 | 3 | 30 | 112 2004 NATURE 432 (7020): 1036-1040 Kittler R; Putz G; Pelletier L; Poser I; Heninger AK; et al. An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division | 1 | 2 |
| 113 | 4 | 69 | 113 2004 NATURE BIOTECHNOLOGY 22 (12): 1533-1537 Agrawal S; Kandimalla ER Antisense and siRNA as agonists of Toll-like receptors | 0 | 1 |
| 114 | 1 | 30 | 114 2004 NATURE BIOTECHNOLOGY 22 (12): 1579-1582 Heidel JD; Hu SW; Liu XF; Triche TJ; Davis ME Lack of interferon response in animals to naked siRNAs | 2 | 2 |
| 115 | 1 | 28 | 115 2004 NATURE GENETICS 36 (2): 183-189 Sen G; Wehrman TS; Myers JW; Blau HM Restriction enzyme-generated siRNA (REGS) vectors and libraries | 12 | 18 |
| 116 | 12 | 196 | 116 2004 NATURE REVIEWS DRUG DISCOVERY 3 (4): 318-329 Dorsett Y; Tuschl T siRNAs: Applications in functional genomics and potential as therapeutics | 9 | 35 |
| 117 | 2 | 102 | 117 2004 NATURE REVIEWS GENETICS 5 (1): 11-22 Carpenter AE; Sabatini DM Systematic genome-wide screens of gene function | 6 | 21 |
| 118 | 1 | 102 | 118 2004 NATURE REVIEWS GENETICS 5 (3): 190-201 Steinmetz LM; Davis RW Maximizing the potential of functional genomics | 0 | 9 |
| 119 | 9 | 127 | 119 2004 NATURE REVIEWS GENETICS 5 (5): 355-365 Mittal V Improving the efficiency of RNA interference in mammals | 2 | 13 |
| 120 | 11 | 59 | 120 2004 NATURE REVIEWS GENETICS 5 (7): 552-557 Hall J Unravelling the general properties of siRNAs: strength in numbers and lessons from the past | 1 | 5 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 121 | 4 | 45 | 121 2004 NATURE STRUCTURAL & MOLECULAR BIOLOGY 11 (7): 599-606 Haley B; Zamore PD Kinetic analysis of the RNAi enzyme complex | 5 | 18 |
| 122 | 1 | 44 | 122 2004 NEOPLASIA 6 (6): 786-795 Faltus T; Yuan JP; Zimmer B; Kramer A; Loibl S; et al. Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu-overexpressing breast cancer cells | 0 | 0 |
| 123 | 6 | 80 | 123 2004 NEUROSCIENCE 126 (1): 1-7 Holen T; Mobbs CV Lobotomy of genes: Use of RNA interference in neuroscience | 0 | 2 |
| 124 | 2 | 33 | 124 2004 NUCLEIC ACIDS RESEARCH 32: W113-W120 Henschel A; Buchholz F; Habermann B DEQOR: a web-based tool for the design and quality control of siRNAs | 0 | 2 |
| 125 | 4 | 21 | 125 2004 NUCLEIC ACIDS RESEARCH 32: W124-W129 Naito Y; Yamada T; Ui-Tei K; Morishita S; Saigo K siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference | 0 | 3 |
| 126 | 1 | 20 | 126 2004 NUCLEIC ACIDS RESEARCH 32 (1): Art. No. e3 Kohli M; Rago C; Lengauer C; Kinzler KW; Vogelstein B Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses | 0 | 2 |
| 127 | 1 | 25 | 127 2004 NUCLEIC ACIDS RESEARCH 32 (3): 893-901 Hsieh AC; Bo RH; Manola J; Vazquez F; Bare O; et al. A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens | 15 | 20 |
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