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| NOD2 IS A GENERAL SENSOR OF PEPTIDOGLYCAN THROUGH MURAMYL DIPEPTIDE (MDP) DETECTION
GIRARDIN SE; BONECA IG; VIALA J; CHAMAILLARD M; LABIGNE A; THOMAS G; PHILPOTT DJ; SANSONETTI PJ JOURNAL OF BIOLOGICAL CHEMISTRY 278: (11) 8869-8872 MAR 14 2003 and the citing papers |
Nodes: 113,
Authors: 417,
Journals: 63,
Outer References: 4091,
Words: 433
Collection span: 2003 - 2005
View: Overview. Sorted by year, source, volume, issue, page.
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 1 | 1 | 60 | 1 2003 AMERICAN JOURNAL OF HUMAN GENETICS 73(6):1282-1292 Brant SR; Panhuysen CIM; Nicolae D; Reddy DM; Bonen DK; et al. MDR1 Ala893 polymorphism is associated with inflammatory bowel disease | 2 | 13 |
| 2 | 1 | 31 | 2 2003 AMERICAN JOURNAL OF OPHTHALMOLOGY 136(4):729-732 Rosenbaum JT; Planck SR; Davey MP; Iwanaga Y; Kurz DE; et al. With a mere nod, uveitis enters a new era | 0 | 2 |
| 3 | 2 | 107 | 3 2003 CELLULAR AND MOLECULAR LIFE SCIENCES 60(9):1793-1804 Dziarski R Recognition of bacterial peptidoglycan by the innate immune system | 1 | 8 |
| 4 | 4 | 71 | 4 2003 CELLULAR MICROBIOLOGY 5(9):581-592 Chamaillard M; Girardin SE; Viala J; Philpott DJ Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation | 11 | 37 |
| 5 | 1 | 95 | 5 2003 CLINICAL AND INVESTIGATIVE MEDICINE-MEDECINE CLINIQUE ET EXPERIMENTALE 26(6):303-314 Newman B; Siminovitch K Inflammatory bowel disease: Crohn's disease and the success of NODern genetics | 0 | 0 |
| 6 | 2 | 250 | 6 2003 CRITICAL REVIEWS IN IMMUNOLOGY 23(5-6):371-401 Phalipon A; Sansonetti PJ Shigellosis: Innate mechanisms of inflammatory destruction of the intestinal epithelium, adaptive immune response, and vaccine development | 0 | 0 |
| 7 | 2 | 54 | 7 2003 CURRENT OPINION IN GASTROENTEROLOGY 19(6):559-564 Abreu MT Immunologic regulation of toll-like receptors in gut epithelium | 1 | 1 |
| 8 | 1 | 92 | 8 2003 CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(5):495-502 Wirtz S; Neurath MF Inflammatory bowel disorders: Gene therapy solutions | 0 | 0 |
| 9 | 1 | 62 | 9 2003 DIGESTIVE AND LIVER DISEASE 35(6):442-449 Annese V; Latiano A; Andriulli A Genetics of inflammatory bowel disease - The beginning of the end or the end of the beginning? | 2 | 6 |
| 10 | 1 | 65 | 10 2003 DIGESTIVE DISEASES 21(4):339-345 Torok HP; Glas J; Lohse P; Folwaczny C Alterations of the CARD15/NOD2 gene and the impact on management and treatment of Crohn's disease patients | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 11 | 4 | 18 | 11 2003 EMBO REPORTS 4(10):932-936 Girardin SE; Philpott DJ; Lemaitre B Sensing microbes by diverse hosts - Workshop on Pattern Recognition Proteins and Receptors | 0 | 2 |
| 12 | 1 | 79 | 12 2003 EUROPEAN JOURNAL OF IMMUNOLOGY 33(7):1767-1775 Underhill DM Toll-like receptors: networking for success | 0 | 36 |
| 13 | 2 | 41 | 13 2003 GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE 27(11):983-985 Reimund JM Leptin and chronic inflammatory bowel disease: the human labyrinth | 0 | 0 |
| 14 | 2 | 10 | 14 2003 GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE 28(3):319-320 Desreumaux P; Malapel M Role of Nod2 in the response of macrophages to toll-like receptor agonists | 0 | 0 |
| 15 | 2 | 42 | 15 2003 GUT 52(11):1533-1535 Aldhous MC; Nimmo ER; Satsangi J NOD2/CARD15 and the Paneth cell: another piece in the genetic jigsaw of inflammatory bowel disease | 1 | 5 |
| 16 | 1 | 24 | 16 2003 GUT 52(11):1591-1597 Ogura Y; Lala S; Xin W; Smith E; Dowds TA; et al. Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis | 7 | 18 |
| 17 | 0 | 27 | 17 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(11):8869-8872 Girardin SE; Boneca IG; Viala J; Chamaillard M; Labigne A; et al. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection | 112 | 112 |
| 18 | 1 | 40 | 18 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(34):31521-31528 Antignac A; Rousselle JC; Namane A; Labigne A; Taha MK; et al. Detailed structural analysis of the peptidoglycan of the human pathogen Neisseria meningitidis | 0 | 1 |
| 19 | 1 | 32 | 19 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(35):32962-32968 Hisamatsu T; Suzuki M; Podolsky DK Interferon-gamma augments CARD4/NOD1 gene and protein expression through interferon regulatory factor-1 in intestinal epithelial cells | 3 | 4 |
| 20 | 1 | 44 | 20 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(41):39822-39829 Meng GX; Grabiec A; Vallon M; Ebe B; Hampel S; et al. Cellular recognition of Tri-/Di-palmitoylated peptides is independent from a domain encompassing the N-terminal seven leucine-rich repeat (LRR)/LRR-like motifs of TLR2 | 0 | 3 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 21 | 5 | 31 | 21 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(43):41702-41708 Girardin SE; Travassos LH; Herve M; Blanot D; Boneca IG; et al. Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2 | 12 | 28 |
| 22 | 4 | 58 | 22 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(49):49044-49052 Wang ZM; Li XN; Cocklin RR; Wang MH; Wang M; et al. Human peptidoglycan recognition protein-L is an N-acetylmuramoyl-L-alanine amidase | 5 | 11 |
| 23 | 1 | 80 | 23 2003 JOURNAL OF IMMUNOLOGY 171(4):1630-1635 Sabroe I; Read RC; Whyte MKB; Dockrell DH; Vogel SN; et al. Toll-like receptors in health and disease: Complex questions remain | 0 | 17 |
| 24 | 5 | 41 | 24 2003 MOLECULAR AND CELLULAR BIOLOGY 23(21):7531-7539 Pauleau AL; Murray PJ Role of Nod2 in the response of macrophages to Toll-like receptor agonists | 11 | 20 |
| 25 | 1 | 42 | 25 2003 NATURE IMMUNOLOGY 4(5):478-484 Leulier F; Parquet C; Pili-Floury S; Ryu JH; Caroff M; et al. The Drosophila immune system detects bacteria through specific peptidoglycan recognition | 15 | 48 |
| 26 | 4 | 12 | 26 2003 NATURE IMMUNOLOGY 4(7):652-654 Kobayashi KS; Eynon EE; Flavell RA Intracellular debugging | 0 | 2 |
| 27 | 3 | 27 | 27 2003 NATURE IMMUNOLOGY 4(7):702-707 Chamaillard M; Hashimoto M; Horie Y; Masumoto J; Qiu S; et al. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid | 35 | 52 |
| 28 | 1 | 115 | 28 2003 NATURE REVIEWS IMMUNOLOGY 3(5):371-382 Inohara N; Nunez G NODs: Intracellular proteins involved in inflammation and apoptosis | 30 | 108 |
| 29 | 1 | 138 | 29 2003 NATURE REVIEWS IMMUNOLOGY 3(7):521-533 Bouma G; Strober W The immunological and genetic basis of inflammatory bowel disease | 8 | 51 |
| 30 | 2 | 230 | 30 2003 PHARMACOLOGY & THERAPEUTICS 100(2):171-194 Fujihara M; Muroi M; Tanamoto K; Suzuki T; Azuma H; et al. Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: roles of the receptor complex | 0 | 3 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 31 | 3 | 40 | 31 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(21):12432-12437 Lenz LL; Mohammadi S; Geissler A; Portnoy DA SecA2-dependent secretion of autolytic enzymes promotes Listeria monocytogenes pathogenesis | 0 | 7 |
| 32 | 2 | 30 | 32 2003 SCIENCE 300(5625):1584-1587 Girardin SE; Boneca IG; Carneiro LAM; Antignac A; Jehanno M; et al. Nod1 detects a unique muropeptide from Gram-negative bacterial peptidoglycan | 43 | 79 |
| 33 | 3 | 10 | 33 2003 SCIENTIST 17(20):29-30 Roberts JP An immunological role in the CARDS | 0 | 0 |
| 34 | 1 | 218 | 34 2003 SHOCK 20(5):402-414 Wang JE; Dahle MK; McDonald M; Foster SJ; Aasen AO; et al. Peptidoglycan and lipoteichoic acid in gram-positive bacterial sepsis: Receptors, signal transduction, biological effects, and synergism | 0 | 5 |
| 35 | 4 | 24 | 35 2003 TRENDS IN CELL BIOLOGY 13(12):610-614 Royet J; Reichhart JM Detection of peptidoglycans by NOD proteins | 0 | 1 |
| 36 | 5 | 62 | 36 2003 TRENDS IN IMMUNOLOGY 24(12):652-658 Girardin SE; Hugot JP; Sansonetti PJ Lessons from Nod2 studies: towards a link between Crohn's disease and bacterial sensing | 4 | 17 |
| 37 | 3 | 355 | 37 2004 ADVANCED DRUG DELIVERY REVIEWS 56(6):727-762 Viswanathan VK; Sharma R; Hecht G Microbes and their products - physiological effects upon mammalian mucosa | 0 | 0 |
| 38 | 4 | 129 | 38 2004 ADVANCES IN APPLIED MICROBIOLOGY, VOL 54 54:291-331 Coombes BK; Hardwidge PR; Finlay BB Interpreting the host-pathogen dialogue through microarrays | 0 | 0 |
| 39 | 2 | 49 | 39 2004 AMERICAN JOURNAL OF GASTROENTEROLOGY 99(12):2376-2384 Arnott IDR; Landers CJ; Nimmo EJ; Drummond HE; Smith BKR; et al. Sero-reactivity to microbial components in Crohn's disease is associated with disease severity and progression, but not NOD2/CARD15 genotype | 0 | 0 |
| 40 | 1 | 76 | 40 2004 AMERICAN JOURNAL OF MANAGED CARE 10(8):544-552 Martins NB; Peppercorn MA Inflammatory bowel disease | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 41 | 3 | 46 | 41 2004 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 286(5):C1100-C1108 Kahlenberg JM; Dubyak GR Mechanisms of caspase-1 activation by P2X(7) receptor-mediated K+ release | 0 | 3 |
| 42 | 1 | 58 | 42 2004 BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY 18(3):451-462 Hugot JP Inflammatory bowel disease: a complex group of genetic disorders | 0 | 0 |
| 43 | 5 | 77 | 43 2004 BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY 18(3):555-568 Philpott DJ; Viala J Towards an understanding of the role of NOD2/CARD15 in the pathogenesis of Crohn's disease | 0 | 0 |
| 44 | 3 | 28 | 44 2004 BIOCHEMICAL JOURNAL 381:213-219 Damiano JS; Oliveira V; Welsh K; Reed JC Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses | 0 | 2 |
| 45 | 3 | 105 | 45 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61(5):537-546 Royet J Drosophila melanogaster innate immunity: an emerging role for peptidoglycan recognition proteins in bacteria detection | 0 | 0 |
| 46 | 1 | 42 | 46 2004 CLINICAL AND EXPERIMENTAL IMMUNOLOGY 135(3):490-496 Walker LJ; Aldhous MC; Drummond HE; Smith BRK; Nimmo ER; et al. Anti-Saccharomyces cerevisiae antibodies (ASCA) in Crohn's disease are associated with disease severity but not NOD2/CARD15 mutations | 1 | 2 |
| 47 | 1 | 42 | 47 2004 CLINICAL IMMUNOLOGY 112(1):85-91 Torok HP; Glas J; Tonenchi L; Mussack T; Folwacznya C Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis | 0 | 0 |
| 48 | 5 | 129 | 48 2004 CLINICAL SCIENCE 107(4):331-341 Mahida YR; Rolfe VE Host-bacterial interactions in inflammatory bowel disease | 0 | 0 |
| 49 | 5 | 15 | 49 2004 COMPTES RENDUS BIOLOGIES 327(6):551-555 Viala M; Sansonetti P; Philpott DJ Nods and 'intracellular' innate immunity | 0 | 0 |
| 50 | 8 | 115 | 50 2004 CURRENT BIOLOGY 14(19):R856-R867 Coombes BK; Valdez Y; Finlay BB Evasive maneuvers by secreted bacterial proteins to avoid innate immune responses | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 51 | 4 | 32 | 51 2004 CURRENT BIOLOGY 14(21):1929-1934 Martinon F; Agostini L; Meylan E; Tschopp J Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome | 0 | 0 |
| 52 | 4 | 91 | 52 2004 CURRENT OPINION IN GASTROENTEROLOGY 20(4):311-317 Rogler G Update in inflammatory bowel disease pathogenesis | 0 | 0 |
| 53 | 2 | 53 | 53 2004 CURRENT OPINION IN GENETICS & DEVELOPMENT 14(3):264-270 Russell RK; Nimmo ER; Satsangi J Molecular genetics of Crohn's disease | 0 | 1 |
| 54 | 3 | 46 | 54 2004 CURRENT OPINION IN IMMUNOLOGY 16(1):21-25 Sousa CRE Activation of dendritic cells: translating innate into adaptive immunity | 0 | 5 |
| 55 | 9 | 56 | 55 2004 CURRENT OPINION IN MICROBIOLOGY 7(1):25-32 Athman R; Philpott D Innate immunity via Toll-like receptors and Nod proteins | 0 | 4 |
| 56 | 1 | 112 | 56 2004 CURRENT PHARMACEUTICAL DESIGN 10(23):2827-2837 Bacher S; Schmitz ML The NF-kappa B pathway as a potential target for autoimmune disease therapy | 0 | 1 |
| 57 | 1 | 36 | 57 2004 CYTOKINE 26(1):16-24 Schippers EF; van t' Veer C; Van Voorden S; Martina CAE; Le Cessie S; et al. TNF-alpha promoter, Nod2 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin | 0 | 0 |
| 58 | 1 | 47 | 58 2004 DIGESTIVE AND LIVER DISEASE 36(1):29-34 Linskens RK; Mallant-Hent RC; Murillo LS; von Blomberg BME; Alizadeh BZ; et al. Genetic and serological markers to identify phenotypic subgroups in a Dutch Crohn's disease population | 0 | 0 |
| 59 | 2 | 18 | 59 2004 DIGESTIVE AND LIVER DISEASE 36(2):121-124 Annese V; Palmieri O; Latiano A; Ardizzone S; Castiglione F; et al. Frequency of NOD2/CARD(15) variants in both sporadic and familial cases of Crohn's disease across Italy - An Italian Group for Inflammatory Bowel Disease Study | 0 | 1 |
| 60 | 5 | 39 | 60 2004 EMBO JOURNAL 23(7):1587-1597 Tanabe T; Chamaillard M; Ogura Y; Zhu L; Qiu S; et al. Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition | 0 | 6 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 61 | 7 | 26 | 61 2004 EMBO REPORTS 5(10):1000-1006 Travassos LH; Girardin SE; Philpott DJ; Blanot D; Nahori MA; et al. Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition | 0 | 0 |
| 62 | 9 | 46 | 62 2004 EUROPEAN JOURNAL OF IMMUNOLOGY 34(7):1777-1782 Girardin SE; Philpott DJ The role of peptidoglycan recognition in innate immunity | 1 | 2 |
| 63 | 3 | 31 | 63 2004 EUROPEAN JOURNAL OF IMMUNOLOGY 34(7):2052-2059 Netea MG; Kullberg BJ; de Jong DJ; Franke B; Sprong T; et al. NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease | 3 | 3 |
| 64 | 1 | 26 | 64 2004 EUROPEAN JOURNAL OF ORAL SCIENCES 112(4):316-319 Folwaczny M; Glas J; Torok HP; Mauermann D; Folwaczny C The 3020insC mutation of the NOD2/CARD15 gene in patients with periodontal disease | 0 | 0 |
| 65 | 7 | 32 | 65 2004 GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE 28(11):1189-1191 Chamaillard M; Desreumaux P Regulatory role of Nod2 in intestinal immunity | 0 | 0 |
| 66 | 1 | 6 | 66 2004 GASTROENTEROLOGY 126(1):371-372 Morre SA; Ouburg S; Klinkenberg-Knol EC; Mulder CJJ; Pena AS The true ligand of the NOD2 receptor is peptidoglycan instead of lipopolysaccharide: A schematic representation of ligand-receptor interactions and NF-kappa B activation | 0 | 0 |
| 67 | 1 | 4 | 67 2004 GASTROENTEROLOGY 126(1):372-373 Bonen DK; Cho JH; Ogura Y; Inohara N; Nunez G The true ligand of the NOD2 receptor is peptidoglycan instead of lipopolysaccharide: A schematic representation of ligand-receptor interactions and NF-kappa B activation - Reply | 0 | 0 |
| 68 | 4 | 148 | 68 2004 GASTROENTEROLOGY 126(6):1533-1549 Ahmad T; Tamboli CP; Jewell D; Colombel JF Clinical relevance of advances in genetics and pharmacogenetics of IBD | 1 | 2 |
| 69 | 1 | 136 | 69 2004 GASTROENTEROLOGY 126(6):1620-1633 Sartor RB Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: Antibiotics, probiotics, and prebiotics | 0 | 7 |
| 70 | 1 | 53 | 70 2004 GASTROENTEROLOGY 127(1):80-93 Martin HM; Campbell BJ; Hart CA; Mpofu C; Nayar M; et al. Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 71 | 1 | 71 | 71 2004 GASTROENTEROLOGY 127(1):224-238 Cario E; Gerken G; Podolsky DK Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C | 0 | 0 |
| 72 | 2 | 50 | 72 2004 GASTROENTEROLOGY 127(2):412-421 Darfeuille-Michaud A; Boudeau J; Bulois P; Neut C; Glasser AL; et al. High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease | 0 | 0 |
| 73 | 1 | 24 | 73 2004 GASTROENTEROLOGY 127(5):1401-1409 Vavricka SR; Musch MW; Chang JE; Nakagawa Y; Phanvijhitsiri K; et al. hPepT1 transports muramyl dipeptide, activating NF-kappa B and stimulating IL-8 secretion in human colonic Caco2/bbe cells | 0 | 0 |
| 74 | 1 | 50 | 74 2004 GENES AND IMMUNITY 5(5):417-425 Arnott IDR; Nimmo ER; Drummond HE; Fennell J; Smith BRK; et al. NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe? | 0 | 1 |
| 75 | 1 | 56 | 75 2004 GUT 53(1):7-9 Weinstock JV; Summers R; Elliott DE Helminths and harmony | 0 | 2 |
| 76 | 1 | 22 | 76 2004 GUT 53(11):1558-1560 Grimm MC; Pavli P NOD2 mutations and Crohn's disease: are Paneth cells and their antimicrobial peptides the link? | 0 | 0 |
| 77 | 6 | 77 | 77 2004 HUMAN MOLECULAR GENETICS 13:R161-R168 Mathew CG; Lewis CM Genetics of inflammatory bowel disease: progress and prospects | 0 | 2 |
| 78 | 2 | 48 | 78 2004 HUMAN MOLECULAR GENETICS 13(16):1715-1725 Li J; Moran T; Swanson E; Julian C; Harris J; et al. Regulation of IL-8 and IL-1 beta expression in Crohn's disease associated NOD2/CARD15 mutations | 1 | 1 |
| 79 | 5 | 40 | 79 2004 IMMUNITY 20(5):637-649 Kaneko T; Goldman WE; Mellroth P; Steiner H; Fukase K; et al. Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway | 2 | 8 |
| 80 | 2 | 84 | 80 2004 IMMUNOLOGICAL REVIEWS 198(1):83-96 Steiner H Peptidoglycan recognition proteins: on and off switches for innate immunity | 1 | 2 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 81 | 6 | 61 | 81 2004 INFECTION AND IMMUNITY 72(3):1487-1495 Kim JG; Lee SJ; Kagnoff MF Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors | 3 | 4 |
| 82 | 3 | 43 | 82 2004 INFLAMMATORY BOWEL DISEASES 10:S11-S15 Hugot JP Genetic origin of IBD | 0 | 0 |
| 83 | 3 | 59 | 83 2004 INFLAMMATORY BOWEL DISEASES 10:S58-S62 Lichtenberger GS; Flavell RA; Alexopoulou L Innate immunity and apoptosis in IBD | 0 | 0 |
| 84 | 3 | 41 | 84 2004 INTERNATIONAL IMMUNOLOGY 16(6):777-786 Wang YT; Hasegawa M; Imamura R; Kinoshita T; Kondo C; et al. PYNOD, a novel Apaf-1/CED4-like protein is an inhibitor of ASC and caspase-1 | 0 | 1 |
| 85 | 2 | 56 | 85 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(10):9642-9652 Eickhoff J; Hanke M; Stein-Garlach M; Kiang TP; Herzberger K; et al. RICK activates a NF-kappa B-dependent anti-human cytomegalovirus response | 0 | 0 |
| 86 | 2 | 51 | 86 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(19):20127-20136 Hardwidge PR; Rodriguez-Escudero I; Goode D; Donohoe S; Eng J; et al. Proteomic analysis of the intestinal epithelial cell response to enteropathogenic Escherichia coli | 0 | 4 |
| 87 | 1 | 33 | 87 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(24):25876-25882 Chen CM; Gong YS; Zhang M; Chen JJ Reciprocal cross-talk between Nod2 and TAK1 signaling pathways | 1 | 1 |
| 88 | 5 | 30 | 88 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(35):36426-36432 Opitz B; Puschel A; Schmeck B; Hocke AC; Rosseau S; et al. Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae | 2 | 2 |
| 89 | 1 | 65 | 89 2004 JOURNAL OF CELL SCIENCE 117(10):1989-1999 Owens DW; Wilson NJ; Hill AJM; Rugg EL; Porter RM; et al. Human keratin 8 mutations that disturb filament assembly observed in inflammatory bowel disease patients | 0 | 4 |
| 90 | 1 | 56 | 90 2004 JOURNAL OF CLINICAL GASTROENTEROLOGY 38(5):S51-S56 Plevy S Do serological markers and cytokines determine the indeterminate? | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 91 | 1 | 25 | 91 2004 JOURNAL OF CLINICAL PERIODONTOLOGY 31(10):890-893 Laine ML; Murillo LS; Morre SA; Winkel EG; Pena AS; et al. CARD15 gene mutations in periodontitis | 0 | 0 |
| 92 | 2 | 60 | 92 2004 JOURNAL OF IMMUNOLOGY 173(9):5398-5405 Vora P; Youdim A; Thomas LS; Fukata M; Tesfay SY; et al. beta-Defensin-2 expression is regulated by TLR signaling in intestinal epithelial cells | 0 | 0 |
| 93 | 4 | 48 | 93 2004 JOURNAL OF IMMUNOLOGY 173(10):6338-6345 Damiano JS; Newman RM; Reed JC Multiple roles of CLAN (caspase-associated recruitment domain, leucine-rich repeat, TPI-containing protein) in the and NAIP CIIA HET-E, and mammalian innate immune response | 0 | 0 |
| 94 | 8 | 47 | 94 2004 JOURNAL OF IMMUNOLOGY 173(12):7339-7348 Stenbak CR; Ryu JH; Leulier F; Pili-Floury S; Parquet C; et al. Peptidoglycan molecular requirements allowing detection by the Drosophila immune deficiency pathway | 0 | 0 |
| 95 | 6 | 76 | 95 2004 JOURNAL OF IMMUNOLOGY 173(12):7416-7425 Stockinger S; Reutterer B; Schaljo B; Schellack C; Brunner S; et al. IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR-and Nod2-independent mechanism | 0 | 0 |
| 96 | 1 | 18 | 96 2004 JOURNAL OF INVESTIGATIVE DERMATOLOGY 122(3):851-852 Kanazawa N; Matsushima S; Kambe N; Tachibana T; Nagai S; et al. Presence of a sporadic case of systemic granulomatosis syndrome with a CARD15 mutation | 0 | 0 |
| 97 | 1 | 9 | 97 2004 LANCET INFECTIOUS DISEASES 4(3):136-137 Behr MA; Semret M; Poon A; Schurr E Crohn's disease, mycobacteria, and NOD2 | 0 | 2 |
| 98 | 4 | 37 | 98 2004 MICROBES AND INFECTION 6(6):609-616 Carneiro LAM; Travassos LH; Philpott DJ Innate immune recognition of microbes through Nod1 and Nod2: implications for disease | 0 | 1 |
| 99 | 2 | 76 | 99 2004 MOLECULAR IMMUNOLOGY 40(12):845-859 Beutler B Innate immunity: an overview | 0 | 12 |
| 100 | 2 | 58 | 100 2004 MOLECULAR MICROBIOLOGY 51(6):1601-1614 Cabanes D; Dussurget O; Dehoux P; Cossart P Auto, a surface associated autolysin of Listeria monocytogenes required for entry into eukaryotic cells and virulence | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 101 | 4 | 9 | 101 2004 NATURE IMMUNOLOGY 5(8):776-778 O'Neill LAJ How NOD-ing off leads to Crohn disease | 0 | 0 |
| 102 | 8 | 49 | 102 2004 NATURE IMMUNOLOGY 5(8):800-808 Watanabe T; Kitani A; Murray PJ; Strober W NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses | 5 | 5 |
| 103 | 5 | 12 | 103 2004 NATURE IMMUNOLOGY 5(11):1099-1100 De Gregorio E; Rappuoli R Inside sensors detecting outside pathogens | 0 | 0 |
| 104 | 4 | 50 | 104 2004 NATURE IMMUNOLOGY 5(11):1166-1174 Viala J; Chaput C; Boneca IG; Cardona A; Girardin SE; et al. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island | 1 | 2 |
| 105 | 5 | 35 | 105 2004 NATURE IMMUNOLOGY 5(11):1175-1180 Bischoff V; Vignal C; Boneca IG; Michel T; Hoffmann JA; et al. Function of the drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria | 0 | 0 |
| 106 | 4 | 121 | 106 2004 NATURE REVIEWS IMMUNOLOGY 4(12):953-964 Sansonetti PJ War and peace at mucosal surfaces | 0 | 0 |
| 107 | 5 | 100 | 107 2004 SEMINARS IN IMMUNOLOGY 16(1):43-53 Ferrandon D; Imler JL; Hoffmann JA Sensing infection in Drosophila: Toll and beyond | 1 | 6 |
| 108 | 2 | 67 | 108 2004 TRENDS IN IMMUNOLOGY 25(12):687-693 O'Neill LAJ TLRs: Professor Mechnikov, sit on your hat | 0 | 1 |
| 109 | 6 | 22 | 109 2004 TRENDS IN MICROBIOLOGY 12(12):529-532 Chamaillard M; Inohara N; Nunez G Battling enteroinvasive bacteria: Nod1 comes to the rescue | 0 | 0 |
| 110 | 3 | 30 | 110 2005 CELLULAR MICROBIOLOGY 7(1):53-61 Uehara A; Yang S; Fujimoto Y; Fukase K; Kusumoto S; et al. Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2-and NOD1-dependent manner, respectively, in human monocytic cells in culture | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 111 | 1 | 85 | 111 2005 CURRENT OPINION IN GASTROENTEROLOGY 21(1):51-58 Elliott DE; Summers RW; Weinstock JV Helminths and the modulation of mucosal inflammation | 0 | 0 |
| 112 | 5 | 62 | 112 2005 GUT 54(1):162-167 Gasche C; Grundtner P Genotypes and phenotypes in Crohn's disease: do they help in clinical management? | 0 | 0 |
| 113 | 6 | 136 | 113 2005 INTERNATIONAL IMMUNOLOGY 17(1):1-14 Takeda K; Akira S Toll-like receptors in innate immunity | 0 | 0 |
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