| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 1 | 1 | 1 2001 AMERICAN JOURNAL OF PATHOLOGY 159(5):1613-1617
Jung A; Schrauder M; Oswald U; Knoll C; Sellberg P; Palmqvist R; Niedobitek G; Brabletz T; Kirchner T
The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D-1, and p16(INK4A) and is a region of low proliferation | 10 | 0
|
| 2 | 1 | 2 2001 BRITISH JOURNAL OF HAEMATOLOGY 115(4):872-880
Li J; Bench AJ; Huntly BJP; Green AR
Mutation and methylation analysis of the transforming growth factor beta receptor II gene in polycythaemia vera | 2 | 0
|
| 3 | 0 | 3 2001 CANCER RESEARCH 61(8):3225-3229
Esteller M; Corn PG; Baylin SB; Herman JG
A gene hypermethylation profile of human cancer | 147 | 147
|
| 4 | 1 | 4 2001 CANCER RESEARCH 61(19):6991-6995
Nakagawa H; Nuovo GJ; Zervos EE; Martin EW; Salovaara R; Aaltonen LA; de la Chapelle A
Age-related hypermethylation of the 5 ' region of MLH1 in normal colonic mucosa is associated with microsatellite- unstable colorectal cancer development | 13 | 4
|
| 5 | 1 | 5 2001 CANCER RESEARCH 61(22):8284-8289
Wong DJ; Paulson TG; Prevo LJ; Galipeau PC; Longton G; Blount PL; Reid BJ
p16(INK4a) lesions are common, early abnormalities that undergo clonal expansion in Barrett's metaplastic epithelium | 12 | 1
|
| 6 | 1 | 6 2001 CANCER RESEARCH 61(23):8375-8380
Yan PS; Chen CM; Shi HD; Rahmatpanah F; Wei SH; Caldwell CW; Huang THM
Dissecting complex epigenetic alterations in breast cancer using CpG island microarrays | 24 | 9
|
| 7 | 1 | 7 2001 CANCER RESEARCH 61(24):8659-8663
Maruyama R; Toyooka S; Toyooka KO; Harada K; Virmani AK; Zochbauer-Muller S; Farinas AJ; Vakar-Lopez F; Minna JD; Sagalowsky A; Czerniak B; Gazdar AF
Aberrant promoter methylation profile of bladder cancer and its relationship to clinicopathological features | 19 | 5
|
| 8 | 2 | 8 2001 GENES & DEVELOPMENT 15(22):2934-2939
Inoue K; Zindy F; Randle DH; Rehg JE; Sherr CJ
Dmp1 is haplo-insufficient for tumor suppression and modifies the frequencies of Arf and p53 mutations in Myc-induced lymphomas | 12 | 0
|
| 9 | 1 | 9 2001 HUMAN MOLECULAR GENETICS 10(26):3001-3007
Esteller M; Fraga MF; Guo MZ; Garcia-Foncillas J; Hedenfalk I; Godwin AK; Trojan J; Vaurs-Barriere C; Bignon YJ; Ramus S; Benitez J; Caldes T; Akiyama Y; Yuasa Y; Launonen V; Canal MJ; Rodriguez R; Capella G; Peinado MA; Borg A; Aaltonen LA; Ponder BA; Baylin SB; Herman JG
DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis | 28 | 14
|
| 10 | 1 | 10 2001 JAPANESE JOURNAL OF CANCER RESEARCH 92(12):1293-1299
Kawada Y; Nakamura M; Ishida E; Shimada K; Oosterwijk E; Uemura H; Hirao Y; Chul KS; Konishi N
Aberrations of the p14(ARF) and p161(INK4a) genes in renal cell carcinomas | 1 | 0
|
| 11 | 1 | 11 2001 JOURNAL OF KOREAN MEDICAL SCIENCE 16(6):756-761
Chung WB; Hong SH; Kim JA; Sohn YK; Kim BW; Kim JW
Hypermethylation of tumor-related genes in genitourinary cancer cell lines | 1 | 0
|
| 12 | 1 | 12 2001 MOLECULAR CANCER THERAPEUTICS 1(1):61-67
Toyooka S; Toyooka KO; Maruyama R; Virmani AK; Girard L; Miyajima K; Harada K; Ariyoshi Y; Takahashi T; Sugio K; Brambilla E; Gilcrease M; Minna JD; Gazdar AF
DNA methylation profiles of lung tumors | 11 | 6
|
| 13 | 1 | 13 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(17):9654-9659
Randle DH; Zindy F; Sherr CJ; Roussel MF
Differential effects of p19(Arf) and p16(Ink4a) loss on senescence of murine bone marrow-derived preB cells and macrophages | 25 | 1
|
| 14 | 1 | 14 2002 ADVANCES IN CANCER RESEARCH, VOL 86 86():67-112
Kern MA; Breuhahn K; Schirmacher P
Molecular pathogenesis of human hepatocellular carcinoma | 0 | 0
|
| 15 | 1 | 15 2002 AMERICAN JOURNAL OF MEDICAL GENETICS 115(3):150-156
Brothman AR
Cytogenetics and molecular genetics of cancer of the prostate | 0 | 0
|
| 16 | 1 | 16 2002 AMERICAN JOURNAL OF PATHOLOGY 160(1):59-66
Siu LLP; Chan JKC; Wong KF; Kwong YL
Specific patterns of gene methylation in natural killer cell lymphomas - p73 is consistently involved | 7 | 2
|
| 17 | 1 | 17 2002 AMERICAN JOURNAL OF PATHOLOGY 160(2):605-612
Lehmann U; Langer F; Feist H; Glockner S; Hasemeier B; Kreipe H
Quantitative assessment of promoter hypermethylation during breast cancer development | 7 | 1
|
| 18 | 1 | 18 2002 AMERICAN JOURNAL OF PATHOLOGY 160(4):1207-1214
Konishi N; Nakamura M; Kishi M; Nishimine M; Ishida E; Shimada K
Heterogeneous methylation and deletion patterns of the INK4a/ARF locus within prostate carcinomas | 2 | 1
|
| 19 | 1 | 19 2002 AMERICAN JOURNAL OF PATHOLOGY 161(2):399-403
Waki T; Tamura G; Tsuchiya T; Sato K; Nishizuka S; Motoyama T
Promoter methylation status of E-cadherin, hMLH1, and p16 genes in nonneoplastic gastric epithelia | 2 | 1
|
| 20 | 1 | 20 2002 AMERICAN JOURNAL OF PATHOLOGY 161(3):1015-1022
Lee S; Kim WH; Jung HY; Yang MH; Kang GH
Aberrant CpG island methylation of multiple genes in intrahepatic cholangiocarcinoma | 0 | 0
|
| 21 | 1 | 21 2002 ANNUAL REVIEW OF PHYSIOLOGY 64():681-708
Zochbauer-Muller S; Gazdar AF; Minna JD
Molecular pathogenesis of lung cancer | 12 | 0
|
| 22 | 1 | 22 2002 ANTIOXIDANTS & REDOX SIGNALING 4(5):833-843
Tuder RM; Voelkel NF
Angiogenesis and pulmonary hypertension: A unique process in a unique disease | 1 | 0
|
| 23 | 1 | 23 2002 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 1602(1):73-87
Ortega S; Malumbres M; Barbacid M
Cyclin D-dependent kinases, INK4 inhibitors and cancer | 12 | 0
|
| 24 | 2 | 24 2002 BIOTECHNIQUES 33(3):632-+
Fraga ME; Esteller M
DNA methylation: A profile of methods and applications | 2 | 0
|
| 25 | 1 | 25 2002 BRITISH JOURNAL OF CANCER 86(12):1888-1892
Bae SI; Lee HS; Kim SH; Kim WH
Inactivation of O-6-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers | 1 | 0
|
| 26 | 1 | 26 2002 BRITISH MEDICAL BULLETIN 64():59-74
Maughan NJ; Quirke P
Pathology - a molecular prognostic approach | 0 | 0
|
| 27 | 1 | 27 2002 BRITISH MEDICAL JOURNAL 324(7343):931-932
Richman S; Adlard J
Left and right sided large bowel cancer - Have significant genetic differences in addition to well known clinical differences | 1 | 0
|
| 28 | 1 | 28 2002 CANCER BIOLOGY & THERAPY 1(3):293-296
Jansen M; Fukushima N; Rosty C; Walter K; Altink R; van Heek T; Hruban R; Offerhaus JG; Goggins M
Aberrant methylation of the 5 ' CpG island of TSLC1 is common in pancreatic ductal adenocarcinoma and is first manifest in high-grade PanINs | 0 | 0
|
| 29 | 2 | 29 2002 CANCER CELL 1(1):37-47
Weber BL
Cancer genomics | 3 | 0
|
| 30 | 1 | 30 2002 CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 11(3):291-297
Virmani AK; Tsou JA; Siegmund KD; Shen LYC; Long TI; Laird PW; Gazdar AF; Laird-Offringa IA
Hierarchical clustering of lung cancer cell lines using DNA methylation markers | 7 | 6
|
| 31 | 1 | 31 2002 CANCER LETTERS 187(1-2):69-75
Pogribny IP; James SJ
De novo methylation of the p16(INK4A) gene in early preneoplastic liver and tumors induced by folate/methyl deficiency in rats | 0 | 0
|
| 32 | 1 | 32 2002 CANCER RESEARCH 62(2):351-355
Soria JC; Rodriguez M; Liu DD; Lee JJ; Hong WK; Mao L
Aberrant promoter methylation of multiple genes in bronchial brush samples from former cigarette smokers | 12 | 3
|
| 33 | 1 | 33 2002 CANCER RESEARCH 62(4):961-966
Liang G; Gonzales FA; Jones PA; Orntoft TF; Thykjaer T
Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2 '- deoxycytidine | 11 | 4
|
| 34 | 1 | 34 2002 CANCER RESEARCH 62(7):2157-2161
van Noesel MM; van Bezouw S; Salomons GS; Voute PA; Pieters R; Baylin SB; Herman JG; Versteeg R
Tumor-specific down-regulation of the tumor necrosis factor- related apoptosis-inducing ligand decoy receptors DcR1 and DcR2 is associated with dense promoter hypermethylation | 4 | 0
|
| 35 | 2 | 35 2002 CANCER RESEARCH 62(11):3214-3220
Shi HD; Yan PS; Chen CM; Rahmatpanah F; Lofton-Day C; Caldwell CW; Huang THM
Expressed CpG island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells | 5 | 2
|
| 36 | 1 | 36 2002 CANCER RESEARCH 62(13):3698-3701
Schagdarsurengin U; Gimm O; Hoang-Vu C; Dralle H; Pfeifer GP; Dammann R
Frequent epigenetic silencing of the CpG island promoter of RASSF1A in thyroid carcinoma | 4 | 1
|
| 37 | 1 | 37 2002 CANCER RESEARCH 62(15):4427-4433
Rhodes DR; Barrette TR; Rubin MA; Ghosh D; Chinnaiyan AM
Meta-analysis of microarrays: Interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer | 9 | 0
|
| 38 | 3 | 38 2002 CANCER RESEARCH 62(15):4519-4524
Paz MF; Avila S; Fraga MF; Pollan M; Capella G; Peinado MA; Sanchez-Cespedes M; Herman JG; Esteller M
Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors | 6 | 3
|
| 39 | 1 | 39 2002 CANCER RESEARCH 62(17):4992-4995
Shen HB; Wang L; Spitz MR; Hong WK; Mao L; Wei QY
A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer | 0 | 0
|
| 40 | 1 | 40 2002 CANCER RESEARCH 62(20):5637-5640
Shibata DM; Sato F; Mori Y; Perry K; Yin J; Wang SN; Xu Y; Olaru A; Selaru F; Spring K; Young J; Abraham JM; Meltzer SJ
Hypermethylation of HPP1 is associated with hMLH1 hypermethylation in gastric adenocarcinomas | 0 | 0
|
| 41 | 1 | 41 2002 CANCER RESEARCH 62(20):5902-5905
Esteller M; Guo MZ; Moreno V; Peinado MA; Capella G; Galm O; Baylin SB; Herman JG
Hypermethylation-associated inactivation of the cellular retinol-binding-protein 1 gene in human cancer | 0 | 0
|
| 42 | 2 | 42 2002 CARCINOGENESIS 23(7):1103-1109
Ballestar E; Esteller M
The impact of chromatin in human cancer: linking DNA methylation to gene silencing | 2 | 1
|
| 43 | 2 | 43 2002 CARCINOGENESIS 23(10):1695-1699
Shibata Y; Haruki N; Kuwabara Y; Ishiguro H; Shinoda N; Sato A; Kimura M; Koyama H; Toyama T; Nishiwaki T; Kudo J; Terashita Y; Konishi S; Sugiura H; Fujii Y
Chfr expression is downregulated by CpG island hypermethylation in esophageal cancer | 0 | 0
|
| 44 | 1 | 44 2002 CLINICAL CANCER RESEARCH 8(1):131-137
Kwong J; Lo KW; To KF; Teo PML; Johnson PJ; Huang DP
Promoter hypermethylation of multiple genes in nasopharyngeal carcinoma | 10 | 3
|
| 45 | 1 | 45 2002 CLINICAL CANCER RESEARCH 8(2):433-437
Wong TS; Chang HW; Tang KC; Wei WI; Kwong DLW; Sham JST; Yuen APW; Kwong YL
High frequency of promoter hypermethylation of the death- associated protein-kinase gene in nasopharyngeal carcinoma and its detection in the peripheral blood of patients | 6 | 1
|
| 46 | 1 | 46 2002 CLINICAL CANCER RESEARCH 8(2):464-470
Chan MWY; Chan LW; Tang NLS; Tong JHM; Lo KW; Lee TL; Cheung HY; Wong WS; Chan PSF; Lai FMM; To KF
Hypermethylation of multiple genes in tumor tissues and voided urine in urinary bladder cancer patients | 6 | 2
|
| 47 | 1 | 47 2002 CLINICAL CANCER RESEARCH 8(2):514-519
Maruyama R; Toyooka S; Toyooka KO; Virmani AK; Zochbauer-Muller S; Farinas AJ; Minna JD; McConnell J; Frenkel EP; Gazdar AF
Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features | 8 | 4
|
| 48 | 1 | 48 2002 CLINICAL CANCER RESEARCH 8(10):3164-3171
Ogi K; Toyota M; Ohe-Toyota M; Tanaka N; Noguchi M; Sonoda T; Kohama G; Tokino T
Aberrant methylation of multiple genes and clinicopathological features in oral squamous cell carcinoma | 1 | 1
|
| 49 | 1 | 49 2002 CLINICAL CANCER RESEARCH 8(10):3210-3218
Lindner DJ; Ma XR; Hu JD; Karra S; Kalvakolanu DV
Thioredoxin reductase plays a critical role in IFN retinoid- mediated tumor-growth control in vivo | 0 | 0
|
| 50 | 1 | 50 2002 CLINICAL CANCER RESEARCH 8(12):3782-3787
Bearzatto A; Conte D; Frattini M; Zaffaroni N; Andriani F; Balestra D; Tavecchio L; Daidone MG; Sozzi G
p16(INK4A) hypermethylation detected by fluorescent methylationspecific PCR in Plasmas from non-small cell lung cancer | 1 | 1
|
| 51 | 3 | 51 2002 CLINICAL IMMUNOLOGY 103(3):213-216
Esteller M
The coming of age of DNA methylation in medicine in the genomics and postgenomics era | 0 | 0
|
| 52 | 3 | 52 2002 CLINICAL IMMUNOLOGY 103(3):217-230
French SW; Dawson DW; Miner MD; Doerr JR; Malone CS; Wall R; Teitell MA
DNA methylation profiling: A new tool for evaluating hematologic malignancies | 2 | 0
|
| 53 | 1 | 53 2002 COMPARATIVE AND FUNCTIONAL GENOMICS 3(3):277-281
Mungall AJ
Meeting review: Epigenetics in development and disease - 21-26 February 2002, Taos Convention Center, Taos, New Mexico, USA | 0 | 0
|
| 54 | 1 | 54 2002 CURRENT OPINION IN ONCOLOGY 14(2):171-179
Rosell R; Monzo M; O'Brate A; Taron M
Translational oncogenomics: toward rational therapeutic decision-making | 5 | 0
|
| 55 | 2 | 55 2002 CURRENT PROBLEMS IN CANCER 26(4):170-+
Yeo CJ
Pancreatic cancer - In brief | 0 | 0
|
| 56 | 1 | 56 2002 DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT 127(33):1701-1703
Arnold C; Usadel H; Blum HE
The role of epigenetics in cancer | 0 | 0
|
| 57 | 1 | 57 2002 DISEASE MARKERS 18(2):73-81
Kiviat NB; Critchlow CW
Novel approaches to identification of biomarkers for detection of early stage cancer | 0 | 0
|
| 58 | 2 | 58 2002 ELECTROPHORESIS 23(11):1677-1681
Fraga MF; Uriol E; Diego LB; Berdasco M; Esteller M; Canal MJ; Rodriguez R
High-performance capillary electrophoretic method for the quantification of 5-methyl 2'-deoxycytidine in genomic DNA: Application to plant, animal and human cancer tissues | 2 | 2
|
| 59 | 4 | 59 2002 EUROPEAN UROLOGY 42(6):622-628
Valenzuela MT; Galisteo R; Zuluaga A; Villalobos M; Nunez MI; Oliver FJ; de Almodovar JMR
Assessing the use of p16(INK4a) promoter gene methylation in serum for detection of bladder cancer | 1 | 1
|
| 60 | 3 | 60 2002 EUROPEAN UROLOGY 42(6):628-630
Nelson W
Assessing the use of p16(INK4a) promoter gene methylation in serum for detection of bladder cancer - Comment | 0 | 0
|
| 61 | 1 | 61 2002 GENOME RESEARCH 12(1):153-157
Galm O; Rountree MR; Bachman KE; Jair KW; Baylin SB; Herman JG
Enzymatic regional methylation assay: A novel method to quantify regional CpG methylation density | 2 | 1
|
| 62 | 1 | 62 2002 HAEMATOLOGICA 87(12):1324-1341
Leone G; Teofili L; Voso MT; Lubbert M
DNA methylation and demethylating drugs in myelodysplastic syndromes and secondary leukemias | 0 | 0
|
| 63 | 1 | 63 2002 HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA 16(1):37-+
Rosty C; Goggins M
Early detection of pancreatic carcinoma | 0 | 0
|
| 64 | 1 | 64 2002 HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA 16(4):775-+
Lynch JP; Hoops TC
The genetic pathogenesis of colorectal cancer | 0 | 0
|
| 65 | 3 | 65 2002 HUMAN GENETICS 111(2):115-127
Garinis GA; Patrinos GP; Spanakis NE; Menounos PG
DNA hypermethylation: when tumour suppressor genes go silent | 0 | 0
|
| 66 | 1 | 66 2002 INTERNATIONAL JOURNAL OF CANCER 100(3):266-275
Russo P; Malacarne D; Falugi C; Trombino S; O'Connor PM
RPR-115135, a farnesyltransferase inhibitor, increases 5-FU- cytotoxicity in ten human colon cancer cell lines: Role of p53 | 1 | 0
|
| 67 | 2 | 67 2002 JAPANESE JOURNAL OF CANCER RESEARCH 93(7):767-773
Konishi N; Nakamura M; Kishi M; Nishimine M; Ishida E; Shimada K
DNA hypermethylation status of multiple genes in prostate adenocarcinomas | 0 | 0
|
| 68 | 1 | 68 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(7):4951-4958
Stimson KM; Vertino PM
Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architecture | 2 | 1
|
| 69 | 1 | 69 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(25):22573-22580
Bakker J; Lin XH; Nelson WG
Methyl-CpG binding domain protein 2 represses transcription from hypermethylated pi-class glutathione S-transferase gene promoters in hepatocellular carcinoma cells | 2 | 1
|
| 70 | 1 | 70 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(31):28176-28181
Beaulieu N; Morin S; Chute IC; Robert MF; Nguyen H; MacLeod AR
An essential role for DNA methyltransferase DNMT3B in cancer cell survival | 1 | 0
|
| 71 | 2 | 71 2002 JOURNAL OF CLINICAL LIGAND ASSAY 25(2):212-214
Cottrell SE
Analysis and applications of DNA methylation-based tumor markers | 0 | 0
|
| 72 | 1 | 72 2002 JOURNAL OF GASTROENTEROLOGY 37():97-101
Toyota M; Itoh F; Kikuchi T; Satoh A; Obata T; Suzuki H; Ishii S; Endo T; Tokino T; Imai K
DNA methylation changes in gastrointestinal disease | 0 | 0
|
| 73 | 1 | 73 2002 JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 30(3):244-250
Idei T; Sakamoto H; Yamamoto T
Terminal restriction fragments of telomere are detectable in plasma and their length correlates with clinical status of ovarian cancer patients | 0 | 0
|
| 74 | 1 | 74 2002 JOURNAL OF INVESTIGATIVE DERMATOLOGY 118(6):941-948
Child FJ; Scarisbrick JJ; Calonje E; Orchard G; Russell-Jones R; Whittaker SJ
Inactivation of tumor suppressor genes p15(INK4b) and p16(INK4a) in primary cutaneous b cell lymphoma | 2 | 0
|
| 75 | 1 | 75 2002 JOURNAL OF NUTRITION 132(8):2424S-2429S
Ehrlich M
DNA hypomethylation, cancer, the immunodeficiency, centromeric region instability, facial anomalies syndrome and chromosomal rearrangements | 0 | 0
|
| 76 | 1 | 76 2002 JOURNAL OF NUTRITION 132(8):2430S-2434S
Yan PS; Chen CM; Shi HD; Rahmatpanah F; Wei SH; Huang TMH
Applications of CpG island microarrays for high-throughput analysis of DNA methylation | 1 | 0
|
| 77 | 1 | 77 2002 JOURNAL OF PATHOLOGY 196(1):1-7
Esteller M; Herman JG
Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours | 31 | 3
|
| 78 | 1 | 78 2002 JOURNAL OF THE NATIONAL CANCER INSTITUTE 94(5):384-390
Sasaki M; Tanaka Y; Perinchery G; Dharia A; Kotcherguina I; Fujimoto SI; Dahiya R
Methylation and inactivation of estrogen, progesterone, and androgen receptors in prostate cancer | 2 | 0
|
| 79 | 1 | 79 2002 LASER CAPTURE MICROSCOPY AND MICRODISSECTION 356():343-351
Brothman AR; Cui J
Methylation in gene promoters: Assessment after laser capture microdissection | 0 | 0
|
| 80 | 1 | 80 2002 LUNG CANCER 38():S9-S17
Niklinski J; Hirsch FR
Molecular approaches to lung cancer evaluation | 0 | 0
|
| 81 | 1 | 81 2002 LUNG CANCER 38():S81-S85
Hirsch FR; Fischer JR; Niklinski J; Zochbauer-Muller S
Future developments in the treatment of lung cancer | 0 | 0
|
| 82 | 2 | 82 2002 MECHANISMS OF AGEING AND DEVELOPMENT 123(12):1649-1654
Yuasa Y
DNA methylation in cancer and ageing | 0 | 0
|
| 83 | 4 | 83 2002 METHODS 27(2):170-178
Siegmund KD; Laird PW
Analysis of complex methylation data | 1 | 1
|
| 84 | 1 | 84 2002 MOLECULAR GENETICS AND METABOLISM 75(1):1-16
Fruhwald MC; Plass C
Global and gene-specific methylation patterns in cancer: Aspects of tumor biology and clinical potential | 3 | 0
|
| 85 | 1 | 85 2002 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 506():137-144
Nakagama H; Ochiai M; Ubagai T; Tajima R; Fujiwara K; Sugimura T; Nagao M
A rat colon cancer model induced by 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine, PhIP | 1 | 0
|
| 86 | 1 | 86 2002 NATURE GENETICS 31(2):141-149
Suzuki H; Gabrielson E; Chen W; Anbazhagan R; van Engeland M; Weijenberg MP; Herman JG; Baylin SB
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer | 14 | 2
|
| 87 | 1 | 87 2002 NATURE REVIEWS CANCER 2(3):210-219
Sidransky D
Emerging molecular markers of cancer | 17 | 4
|
| 88 | 5 | 88 2002 NATURE REVIEWS GENETICS 3(6):415-428
Jones PA; Baylin SB
The fundamental role of epigenetic events in cancer | 60 | 15
|
| 89 | 1 | 89 2002 NUCLEIC ACIDS RESEARCH 30(5):art. no.-e21
Adorjan P; Distler J; Lipscher E; Model F; Muller J; Pelet C; Braun A; Florl AR; Gutig D; Grabs G; Howe A; Kursar M; Lesche R; Leu E; Lewin A; Maier S; Muller V; Otto T; Scholz C; Schulz WA; Seifert HH; Schwope I; Ziebarth H; Berlin K; Piepenbrock C; Olek A
Tumour class prediction and discovery by microarray-based DNA methylation analysis | 15 | 0
|
| 90 | 1 | 90 2002 ONCOGENE 21(13):2114-2117
Ueki T; Walter KM; Skinner H; Jaffee E; Hruban RH; Goggins M
Aberrant CpG island methylation in cancer cell lines arises in the primary cancers from which they were derived | 5 | 3
|
| 91 | 1 | 91 2002 ONCOGENE 21(27):4231-4236
Hasegawa M; Nelson HH; Peters E; Ringstrom E; Posner M; Kelsey KT
Patterns of gene promoter methylation in squamous cell cancer of the head and neck | 3 | 1
|
| 92 | 3 | 92 2002 ONCOGENE 21(27):4345-4349
Harada K; Toyooka S; Maitra A; Maruyama R; Toyooka KO; Timmons CF; Tomlinson GE; Mastrangelo D; Hay RJ; Minna JD; Gazdar AF
Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines | 4 | 0
|
| 93 | 1 | 93 2002 ONCOGENE 21(31):4822-4829
Sato M; Horio Y; Sekido Y; Minna JD; Shimokata K; Hasegawa Y
The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14(ARF), p16(INK4a) and RASSF1A in human lung cancer cell lines | 0 | 0
|
| 94 | 1 | 94 2002 ONCOGENE 21(35):5400-5413
Ehrlich M
DNA methylation in cancer: too much, but also too little | 9 | 1
|
| 95 | 3 | 95 2002 ONCOGENE 21(35):5427-5440
Esteller M
CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future | 4 | 1
|
| 96 | 3 | 96 2002 ONCOGENE 21(35):5450-5461
Tsou JA; Hagen JA; Carpenter CL; Laird-Offringa IA
DNA methylation analysis: a powerful new tool for lung cancer diagnosis | 0 | 0
|
| 97 | 3 | 97 2002 ONCOGENE 21(35):5462-5482
Widschwendter M; Jones PA
DNA methylation and breast carcinogenesis | 1 | 0
|
| 98 | 2 | 98 2002 ONCOGENE 21(35):5483-5495
Christman JK
5-Azacytidine and 5-aza-2 '-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy | 2 | 0
|
| 99 | 3 | 99 2002 ONCOGENE 21(35):5496-5503
Karpf AR; Jones DA
Reactivating the expression of methylation silenced genes in human cancer | 3 | 1
|
| 100 | 4 | 100 2002 ONCOGENE 21(45):6915-6935
Zabarovsky ER; Lerman MI; Minna JD
Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers | 2 | 0
|
| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 101 | 3 | 101 2002 ONCOGENE 21(45):6949-6959
McWilliams A; MacAulay C; Gazdar AF; Lam S
Innovative molecular and imaging approaches for the detection of lung cancer and its precursor lesions | 0 | 0
|
| 102 | 3 | 102 2002 ONCOGENE 21(48):7298-7306
Wistuba II; Mao L; Gazdar AF
Smoking molecular damage in bronchial epithelium | 1 | 0
|
| 103 | 2 | 103 2002 ONCOGENE 21(58):9033-9042
Mukai T; Sekiguchi M
Gene silencing in phenomena related to DNA repair | 0 | 0
|
| 104 | 4 | 104 2002 ONCOLOGIST 7(5):451-457
Zochbauer-Muller S; Minna JD; Gazdar AF
Aberrant DNA methylation in lung cancer: Biological and clinical implications | 0 | 0
|
| 105 | 1 | 105 2002 PATHOBIOLOGY 70(1):1-10
Fernandez PL; Hernandez L; Farre X; Campo E; Cardesa A
Alterations of cell cycle-regulatory genes in prostate cancer | 0 | 0
|
| 106 | 1 | 106 2002 PATHOLOGY RESEARCH AND PRACTICE 198(12):785-794
Tsujimoto H; Hagiwara A; Sugihara H; Hattori T; Yamagishi H
Promoter methylations of p16(INK4a) and p14(ARF) genes in early and advanced gastric cancer. Correlations of the modes of their occurrence with histologic type | 0 | 0
|
| 107 | 1 | 107 2002 SEMINARS IN CANCER BIOLOGY 12(4):261-266
Nowell PC
Tumor progression: a brief historical perspective | 1 | 0
|
| 108 | 3 | 108 2002 SEMINARS IN CANCER BIOLOGY 12(5):359-371
Catteau A; Morris JR
BRCA1 methylation: a significant role in tumour development? | 2 | 0
|
| 109 | 1 | 109 2002 TOXICOLOGICAL SCIENCES 68(1):51-58
Watson RE; Goodman JI
Effects of phenobarbital on DNA methylation in GC-rich regions of hepatic DNA from mice that exhibit different levels of susceptibility to liver tumorigenesis | 0 | 0
|
| 110 | 1 | 110 2003 ACTA CYTOLOGICA 47(2):247-252
Pu RT; Clark DP
Detection of DNA methylation - Potential applications to diagnostic cytopathology | 0 | 0
|
| 111 | 2 | 111 2003 AMERICAN JOURNAL OF HUMAN GENETICS 72(1):216-218
Schneider-Stock R; Giers A; Motsch C; Boltze C; Evert M; Freigang B; Roessner A
Hereditary p16-Leiden mutation in a patient with multiple head and neck tumors | 0 | 0
|
| 112 | 1 | 112 2003 BRITISH JOURNAL OF CANCER 88(2):217-222
Klump B; Hsieh CJ; Nehls O; Dette S; Holzmann K; Kiesslich R; Jung M; Sinn U; Ortner M; Porschen R; Gregor M
Methylation status of p14ARF and p16INK4a as detected in pancreatic secretions | 0 | 0
|
| 113 | 1 | 113 2003 BRITISH JOURNAL OF CANCER 88(4):521-529
Matsukura S; Soejima H; Nakagawachi T; Yakushiji H; Ogawa A; Fukuhara M; Miyazaki K; Nakabeppu Y; Sekiguchi M; Mukai T
CpG methylation of MGMT and hMLHI promoter in hepatocellular carcinoma associated with hepatitis viral infection | 0 | 0
|
| 114 | 2 | 114 2003 BRITISH JOURNAL OF HAEMATOLOGY 120(6):1051-1054
Lincz LF; Scorgie FE; Kerridge I; Potts R; Spencer A; Enno A
Methionine synthase genetic polymorphism MS A2756G alters susceptibility to follicular but not diffuse large B-cell non- Hodgkin's lymphoma or multiple myeloma | 0 | 0
|
| 115 | 2 | 115 2003 CANCER GENETICS AND CYTOGENETICS 140(2):113-117
Yuan BZ; Durkin ME; Popescu NC
Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers | 0 | 0
|
| 116 | 2 | 116 2003 CANCER GENETICS AND CYTOGENETICS 142(1):21-24
Gonzalez-Gomes P; Bello MJ; Arjona D; Alonso ME; Lomas J; Aminoso C; de Campos JM; Sarasa JL; Gutierrez M; Rey JA
CpG island methylation of tumor-related genes in three primary central nervous system lymphomas in immunocompetent patients | 0 | 0
|
| 117 | 8 | 117 2003 CANCER LETTERS 190(2):125-133
Nephew KP; Huang THM
Epigenetic gene silencing in cancer initiation and progression | 0 | 0
|
| 118 | 1 | 118 2003 CANCER RESEARCH 63(2):498-504
Lin XH; Nelson WG
Methyl-CpG-binding domain protein-2 mediates transcriptional repression associated with hypermethylated GSTP1 CpG islands in MCF-7 breast cancer cells | 0 | 0
|
| 119 | 1 | 119 2003 CANCER RESEARCH 63(4):787-792
Ricciardiello L; Goel A; Mantovani V; Fiorini T; Fossi S; Chang DK; Lunedei V; Pozzato P; Zagari RM; De Luca L; Fuccio L; Martinelli GN; Roda E; Boland CR; Bazzoli F
Frequent loss of hMLH1 by promoter hypermethylation leads to microsatellite instability in adenomatous polyps of patients with a single first-degree member affected by colon cancer | 0 | 0
|
| 120 | 6 | 120 2003 CANCER RESEARCH 63(5):1114-1121
Paz MF; Fraga MF; Avila S; Guo MZ; Pollan M; Herman JG; Esteller M
A systematic profile of DNA methylation in human cancer cell lines | 0 | 0
|
| 121 | 1 | 121 2003 CANCER RESEARCH 63(7):1608-1614
Goel A; Arnold CN; Niedzwiecki D; Chang DK; Ricciardiello L; Carethers JM; Dowell JM; Wasserman L; Compton C; Mayer RJ; Bertagnolli MM; Boland CR
Characterization of sporadic colon cancer by patterns of genomic instability | 0 | 0
|
| 122 | 5 | 122 2003 CANCER RESEARCH 63(7):1639-1643
Spugnardi M; Tommasi S; Dammann R; Pfeifer GP; Hoon DSB
Epigenetic inactivation of RAS Association Domain Family Protein 1 (RASSF1A) in malignant cutaneous melanoma | 0 | 0
|
| 123 | 1 | 123 2003 CARCINOGENESIS 24(1):47-51
Corn PG; Summers MK; Fogt F; Virmani AK; Gazdar AF; Halazonetis TD; El-Deiry WS
Frequent hypermethylation of the 5 ' CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer | 0 | 0
|
| 124 | 3 | 124 2003 CARCINOGENESIS 24(1):81-90
Sohn KJ; Stempak JM; Reid S; Shirwadkar S; Mason JB; Kim YI
The effect of dietary folate on genomic and p53-specific DNA methylation in rat colon | 0 | 0
|
| 125 | 2 | 125 2003 CARCINOGENESIS 24(2):193-198
House MG; Guo MZ; Iacobuzio-Donahue C; Herman JG
Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas | 0 | 0
|
| 126 | 2 | 126 2003 CURRENT DRUG METABOLISM 4(1):11-31
Villar-Garea A; Esteller M
DNA demethylating agents and chromatin-remodelling drugs: Which, how and why? | 0 | 0
|
| 127 | 1 | 127 2003 FRONTIERS IN BIOSCIENCE 8():S175-S184
Costello JF
DNA methylation in brain development and gliomagenesis | 0 | 0
|
| 128 | 2 | 128 2003 INTERNATIONAL JOURNAL OF CANCER 103(2):153-160
Toyooka S; Maruyama R; Toyooka KO; McLerran D; Feng ZD; Fukuyama Y; Virmani AK; Zochbauer-Muller S; Tsukuda K; Sugio K; Shimizu N; Shimizu K; Lee H; Chen CY; Fong KM; Gilcrease M; Roth JA; Minna JD; Gazdar AF
Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer | 0 | 0
|
| 129 | 1 | 129 2003 INTERNATIONAL JOURNAL OF ONCOLOGY 22(3):601-608
Gonzalez-Gomez P; Bello MJ; Arjona D; Lomas J; Alonso ME; De Campos JM; Vaquero J; Isla A; Gutierrez M; Rey JA
Promoter hypermethylation of multiple genes in astrocytic gliomas | 0 | 0
|
| 130 | 3 | 130 2003 INTERNATIONAL JOURNAL OF ONCOLOGY 22(4):869-874
Wong TS; Tang KC; Kwong DLW; Sham JST; Wei WI; Kwong YL; Yuen APW
Differential gene methylation in undifferentiated nasopharyngeal carcinoma | 0 | 0
|
| 131 | 3 | 131 2003 JOURNAL OF CELLULAR BIOCHEMISTRY 88(1):138-143
Shi HD; Maier S; Nimmrich I; Yan PS; Caldwell CW; Olek A; Huang THM
Oligonucleotide-based microarray for DNA methylation analysis: Principles and applications | 1 | 1
|
| 132 | 1 | 132 2003 JOURNAL OF CELLULAR BIOCHEMISTRY 88(5):885-898
Shivapurkar N; Reddy J; Chaudhary PM; Gazdar AF
Apoptosis and lung cancer: A review | 0 | 0
|
| 133 | 1 | 133 2003 JOURNAL OF CLINICAL INVESTIGATION 111(2):265-273
Yao XM; Hu JF; Daniels M; Shiran H; Zhou XJ; Yan HF; Lu HQ; Zeng ZL; Wang QX; Li T; Hoffman AR
A methylated oligonucleotide inhibits IGF2 expression and enhances survival in a model of hepatocellular carcinoma | 0 | 0
|
| 134 | 1 | 134 2003 JOURNAL OF CLINICAL INVESTIGATION 111(6):887-895
Wang YC; Lu YP; Tseng RC; Lin RK; Chang JW; Chen JT; Shih CM; Chen CY
Inactivation of hMLH1 and hMSH2 by promoter methylation in primary non-small cell lung tumors and matched sputum samples | 0 | 0
|
| 135 | 2 | 135 2003 JOURNAL OF IMMUNOLOGY 170(1):218-227
Thomas RM; Haleem K; Siddique AB; Simmons WJ; Sen N; Zhang DJ; Tsiagbe VK
Regulation of mouse mammary tumor virus env transcriptional activator initiated mammary tumor virus superantigen transcripts in lymphomas of SJL/J mice: Role of Ikaros, demethylation, and chromatin structural change in the transcriptional activation of mammary tumor virus superantigen | 0 | 0
|
| 136 | 2 | 136 2003 JOURNAL OF MEDICAL GENETICS 40(1):25-33
Smiraglia DJ; Smith LT; Lang JC; Rush LJ; Dai Z; Schuller DE; Plass C
Differential targets of CpG island hypermethylation in primary and metastatic head and neck squamous cell carcinoma (HNSCC) | 0 | 0
|
| 137 | 1 | 137 2003 JOURNAL OF SURGICAL ONCOLOGY 82(3):194-200
Matsukura S; Miyazaki K; Yakushiji H; Ogawa A; Chen YX; Sekiguchi M
Combined loss of expression of O-6-methylguanine-DNA methyltransferase and hMLH1 accelerates progression of hepatocellular Combined loss of expression of O-6- methylguanine-DNA methyltransferase and hMLH1 accelerates progression of hepatocellular carcinoma | 0 | 0
|
| 138 | 4 | 138 2003 JOURNAL OF THE NATIONAL CANCER INSTITUTE 95(4):327-330
Sato N; Maehara N; Su GH; Goggins M
Effects of 5-aza-2 '-deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness | 0 | 0
|
| 139 | 3 | 139 2003 MEDICAL HYPOTHESES 60(4):578-583
Burzynski SR
Gene silencing - a new theory of aging | 0 | 0
|
| 140 | 1 | 140 2003 MOLECULAR CARCINOGENESIS 36(1):23-31
Yin D; Xie D; Hofmann WK; Zhang WX; Asotra K; Wong R; Black KL; Koeffler HP
DNA repair gene O-6-methylguanine-DNA methyltransferase: Promoter hypermethylation associated with decreased expression and G : C to A : T mutations of p53 in brain tumors | 0 | 0
|
| 141 | 20 | 141 2003 NATURE REVIEWS CANCER 3(4):253-266
Laird PW
The power and the promise of DNA methylation markers | 0 | 0
|
| 142 | 4 | 142 2003 NUCLEIC ACIDS RESEARCH 31(2):art. no.-e2
Stach D; Schmitz OJ; Stilgenbauer S; Benner A; Dohner H; Wiessler M; Lyko F
Capillary electrophoretic analysis of genomic DNA methylation levels | 0 | 0
|
| 143 | 2 | 143 2003 NUCLEIC ACIDS RESEARCH 31(6):1765-1774
Fraga MF; Ballestar E; Montoya G; Taysavang P; Wade PA; Esteller M
The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties | 0 | 0
|
| 144 | 2 | 144 2003 ONCOGENE 22(2):274-280
Miyamoto K; Asada K; Fukutomi T; Okochi E; Yagi Y; Hasegawa T; Asahara T; Sugimura T; Ushijima T
Methylation-associated silencing of heparan sulfate D- glucosaminyl 3-O-sulfotransferase-2 (3-OST-2) in human breast, colon, lung and pancreatic cancers | 0 | 0
|
| 145 | 2 | 145 2003 ONCOGENE 22(3):461-466
Honorio S; Agathanggelou A; Wernert N; Rothe M; Maher ER; Latif F
Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours | 0 | 0
|
| 146 | 1 | 146 2003 ONCOGENE 22(11):1600-1610
Haviernik P; Schmidt M; Hu XR; Wolff L
Consistent inactivation of p19(Arf) but not p15(Ink4b) in murine myeloid cells transformed in vivo by deregulated c-Myc | 0 | 0
|
| 147 | 1 | 147 2003 ONCOGENE 22(11):1668-1677
Nasr AF; Nutini M; Palombo B; Guerra E; Alberti S
Mutations of TP53 induce loss of DNA methylation and amplification of the TROP1 gene | 0 | 0
|
| 148 | 1 | 148 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(6):3113-3118
Roca R; Kypta RM; Vivanco MD
Loss of P16(INK4a) results in increased glucocorticoid receptor activity during fibrosarcoma development | 0 | 0
|