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Mon Jun 24 17:27:58 2002

Articles citing "Specificity and mechanism of action of some commonly used protein kinase inhibitors," by Davies et al. Biochemical Journal, 351: 95-105, part 1, Oct. 1, 2000

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01 2000 BIOCHEMICAL JOURNAL 351():95-105
Davies SP; Reddy H; Caivano M; Cohen P
Specificity and mechanism of action of some commonly used protein kinase inhibitors
165165
12 2001 ACTA PHYSIOLOGICA SCANDINAVICA 173(1):151-157
Kevil CG; Bullard DC
In vitro culture and characterization of gene targeted mouse endothelium
 0
13 2001 AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 281(6):L1500-L1511
Becker PM; Verin AD; Booth MA; Liu F; Birukova A; Garcia JGN
Differential regulation of diverse physiological responses to VEGF in pulmonary endothelial cells
 0
14 2001 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 281(4):F693-F706
Lieberthal W; Fuhro R; Andry CC; Rennke H; Abernathy VE; Koh JS; Valeri R; Levine JS
Rapamycin impairs recovery from acute renal failure: role of cell-cycle arrest and apoptosis of tubular cells
10
15 2001 ANNUAL REVIEW OF BIOCHEMISTRY 70():535-602
Vanhaesebroeck B; Leevers SJ; Ahmadi K; Timms J; Katso R; Driscoll PC; Woscholski R; Parker PJ; Waterfield MD
Synthesis and function of 3-phosphorylated inositol lipids
391
16 2001 ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY 17():405-433
Shogren-Knaak MA; Alaimo PJ; Shokat KM
Recent advances in chemical approaches to the study of biological systems
20
17 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 287(3):607-613
Willard FS; Berven LA; Crouch MF
Lysophosphatidic acid activates the 70-kDa S6 kinase via the lipoxygenase pathway
10
18 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 287(4):1009-1016
Grandvaux N; Elsen S; Vignais PV
Oxidant-dependent phosphorylation of p40phox in B lymphocytes
 0
19 2001 BIOCHEMICAL JOURNAL 357():297-303
Kortylewski M; Heinrich PC; Kauffmann ME; Bohm M; Mackiewicz A; Behrmann I
Mitogen-activated protein kinases control p27/Kip1 expression and growth of human melanoma cells
 0
110 2001 BIOCHEMICAL JOURNAL 357():661-672
Chen ZG; Eggerman TL; Patterson AP
Phosphorylation is a regulatory mechanism in apolipoprotein B mRNA editing
10
111 2001 BIOCHEMICAL JOURNAL 357():867-873
Schmoll D; Grempler R; Barthel A; Joost HG; Walther R
Phorbol ester-induced activation of mitogen-activated protein kinase/extracellular-signal-regulated kinase kinase and extracellular-signal-regulated protein kinase decreases glucose-6-phosphatase gene expression
10
312 2001 BIOCHEMICAL JOURNAL 359():1-16
Frame S; Cohen P
GSK3 takes centre stage more than 20 years after its discovery
120
113 2001 BIOCHEMICAL JOURNAL 359():611-619
Patel S; Lochhead PA; Rena G; Sutherland C
Antagonistic effects of phorbol esters on insulin regulation of insulin-like growth factor-binding protein-1 (IGFBP-1) but not glucose-6-phosphatase gene expression
10
114 2001 BIOCHEMICAL JOURNAL 359():639-649
Somwar R; Kim DY; Sweeney G; Huang C; Niu WY; Lador C; Ramlal T; Klip A
GLUT4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells: potential activation of GLUT4 via p38 mitogen-activated protein kinase
21
115 2001 BIOCHEMICAL JOURNAL 360():449-459
Browne GJ; Delibegovic M; Keppens S; Stalmans W; Cohen PTW
The level of the glycogen targetting regulatory subunit R5 of protein phosphatase 1 is decreased in the livers of insulin- dependent diabetic rats and starved rats
20
116 2001 BIOCHEMICAL PHARMACOLOGY 62(10):1379-1390
Son MH; Kang KW; Lee CH; Kim SG
Potentiation of cadmium-induced cytotoxicity by sulfur amino acid deprivation through activation of extracellular signal- regulated kinase1/2 (ERK1/2) in conjunction with p38 kinase or c-jun N-terminal kinase (JNK) - Complete inhibition of the potentiated toxicity by U0126 an ERK1/2 and p38 kinase inhibitor
30
117 2001 BIOCHEMICAL PHARMACOLOGY 62(12):1605-1611
Ho AK; Price L; Mackova M; Chik CL
Potentiation of cyclic AMP and cyclic GMP accumulation by p38 mitogen-activated protein kinase (p38MAPK) inhibitors in rat pinealocytes
 0
118 2001 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1538(2-3):206-217
Fredriksson JM; Thonberg H; Ohlson KBE; Ohba K; Cannon B; Nedergaard J
Analysis of inhibition by H89 of UCP1 gene expression and thermogenesis indicates protein kinase A mediation of beta(3)- adrenergic signalling rather than beta(3)-adrenoceptor antagonism by H89
31
119 2001 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 11(5):635-639
Smith DG; Buffet M; Fenwick AE; Haigh D; Ife RJ; Saunders M; Slingsby BP; Stacey R; Ward RW
3-anilino-4-arylmaleimides: Potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3)
20
120 2001 BLOOD 98(5):1374-1381
Somervaille TCP; Linch DC; Khwaja A
Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax
 0
121 2001 BLOOD 98(7):2175-2182
Puig-Kroger A; Relloso M; Fernandez-Capetillo O; Zubiaga A; Silva A; Bernabeu C; Corbi AL
Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells
10
122 2001 BLOOD 98(10):2909-2916
Del Corno M; Liu QH; Schols D; Clercq EC; Gessani S; Freedman BD; Collman RG
HIV-1 gp120 and chemokine activation of Pyk2 and mitogen- activated protein kinases in primary macrophages mediated by calcium-dependent, pertussis toxin-insensitive chemokine receptor signaling
 0
123 2001 BRITISH JOURNAL OF CANCER 85(8):1175-1184
Ding S; Chamberlain M; McLaren A; Goh LB; Duncan I; Wolf CR
Cross-talk between signalling pathways and the multidrug resistant protein MDR-1
 0
124 2001 BRITISH JOURNAL OF PHARMACOLOGY 134(8):1724-1730
Utsunomiya T; Satoh S; Ikegaki I; Toshima Y; Asano T; Shimokawa H
Antianginal effects of hydroxyfasudil, a Rho-kinase inhibitor, in a canine model of effort angina
 0
125 2001 CANCER RESEARCH 61(10):4278-4282
Gupta AK; Bakanauskas VJ; Cerniglia GJ; Chen Y; Bernhard EJ; Muschel RJ; McKenna WG
The Ras radiation resistance pathway
30
126 2001 CANCER RESEARCH 61(13):5106-5115
Dai Y; Yu CR; Singh V; Tang L; Wang ZL; McInistry R; Dent P; Grant S
Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells
30
127 2001 CANCER RESEARCH 61(20):7479-7487
Ghose A; Fleming J; El-Bayoumy K; Harrison PR
Enhanced sensitivity of human oral carcinomas to induction of apoptosis by selenium compounds: Involvement of mitogen- activated protein kinase and Fas pathways
 0
128 2001 CARCINOGENESIS 22(7):1035-1042
Kermorgant S; Aparicio T; Dessirier V; Lewin MJM; Lehy T
Hepatocyte growth factor induces colonic cancer cell invasiveness via enhanced motility and protease overproduction. Evidence for PI3 kinase and PKC involvement
20
129 2001 CELL DEATH AND DIFFERENTIATION 8(8):841-849
Tee AR; Proud CG
Staurosporine inhibits phosphorylation of translational regulators linked to mTOR
50
130 2001 CELL MOTILITY AND THE CYTOSKELETON 48(4):235-244
Pletjushkina OJ; Rajfur Z; Pomorski P; Oliver TN; Vasiliev JM; Jacobson KA
Induction of cortical oscillations in spreading cells by depolymerization of microtubules
20
131 2001 CELL MOTILITY AND THE CYTOSKELETON 50(4):207-217
Pullar CE; Isseroff RR; Nuccitelli R
Cyclic AMP-dependent protein kinase a plays a role in the directed migration of human keratinocytes in a DC electric field
 0
132 2001 CHEMICAL REVIEWS 101(8):2365-2380
Leslie NR; Biondi RM; Alessi DR
Phosphoinositide-regulated kinases and phosphoinositide phosphatases
30
233 2001 CHEMICAL REVIEWS 101(8):2381-2411
Shabb JB
Physiological substrates of cAMP-dependent protein kinase
 0
134 2001 CURRENT OPINION IN CHEMICAL BIOLOGY 5(4):360-367
Alaimo PJ; Shogren-Knaak MA; Shokat KM
Chemical genetic approaches for the elucidation of signaling pathways
50
135 2001 CURRENT PHARMACEUTICAL DESIGN 7(6):475-507
Balla T
Pharmacology of phosphoinositides, regulators of multiple cellular functions
20
136 2001 DIABETES 50(5):937-946
Lochhead PA; Coghlan M; Rice SQJ; Sutherland C
Inhibition of GSK-3 selectively reduces glucose-B-phosphatase and phosphoenolpyruvate carboxykinase gene expression
42
137 2001 DIABETES 50(10):2237-2243
Buteau J; Foisy S; Rhodes CJ; Carpenter L; Biden TJ; Prentki M
Protein kinase C zeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation
11
138 2001 EMBO JOURNAL 20(16):4360-4369
Knebel A; Morrice N; Cohen P
A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38 delta
51
239 2001 ENDOCRINE-RELATED CANCER 8(3):237-248
Stein RC
Prospects for phosphoinositide 3-kinase inhibition as a cancer treatment
10
140 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(5):1373-1381
Harcourt JL; Offermann MK
Multiple signaling cascades are differentially involved in gene induction by double stranded RNA in interferon-alpha-primed cells
20
141 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(16):4423-4429
Delehedde M; Sergeant N; Lyon M; Rudland PS; Fernig DG
Hepatocyte growth factor/scatter factor stimulates migration of rat mammary fibroblasts through both mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt pathways
10
242 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(19):5001-5010
Cohen P
The role of protein phosphorylation in human health and disease - Delivered on June 30th 2001 at the FEBS Meeting in Lisbon
10
143 2001 EXPERIMENTAL CELL RESEARCH 266(2):292-302
Sinnett-Smith J; Lunn JA; Leopoldt D; Rozengurt E
Y-27632, an inhibitor of Rho-associated kinases, prevents tyrosine phosphorylation of focal adhesion kinase and paxillin induced by bombesin: Dissociation from tyrosine phosphorylation of p130(cas)
30
144 2001 EXPERIMENTAL CELL RESEARCH 267(1):144-151
Sundstrom M; Alfredsson J; Olsson N; Nilsson G
Stem cell factor-induced migration of mast cells requires p38 mitogen-activated protein kinase activity
10
145 2001 EXPERT OPINION ON INVESTIGATIONAL DRUGS 10(6):1085-1098
Berrie CP
Phosphoinositide 3-kinase inhibition in cancer treatment
 0
146 2001 EXPERT OPINION ON INVESTIGATIONAL DRUGS 10(12):2117-2140
Goekjian PG; Jirousek MR
Protein kinase C inhibitors as novel anticancer drugs
10
147 2001 FEBS LETTERS 493(2-3):80-84
Muranyi A; Zhang RX; Liu FZ; Hirano K; Ito M; Epstein HF; Hartshorne DJ
Myotonic dystrophy protein kinase phosphorylates the myosin phosphatase targeting subunit and inhibits myosin phosphatase activity
30
148 2001 FEBS LETTERS 496(1):44-48
Sarno S; Reddy H; Meggio F; Ruzzene M; Davies SP; Donella-Deana A; Shugar D; Pinna LA
Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site- directed inhibitor of protein kinase CK2 ('casein kinase-2')
60
249 2001 FEBS LETTERS 502(1-2):21-24
Mody N; Leitch J; Armstrong C; Dixon J; Cohen P
Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway
53
150 2001 FEBS LETTERS 502(3):84-88
De Mesquita DD; Zhan Q; Crossley L; Badwey JA
p90-RSK and Akt may promote rapid phosphorylation/inactivation of glycogen synthase kinase 3 in chemoattractant-stimulated neutrophils
 0
151 2001 HYPERTENSION 38(6):1307-1310
Masumoto A; Hirooka Y; Shimokawa H; Hironaga K; Setoguchi S; Takeshita A
Possible involvement of Rho-kinase in the pathogenesis of hypertension in humans
32
152 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 19(4):811-819
Du LT; Smolewski P; Bedner E; Traganos F; Darzynkiewicz Z
Selective protection of mitogenically stimulated human lymphocytes but not leukemic cells from cytosine arabinoside- induced apoptosis by LY294002, a phosphoinositol-3 kinase inhibitor
20
153 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(19):15659-15665
Rosado JA; Sage SO
Role of the ERK pathway in the activation of store-mediated calcium entry in human platelets
11
154 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(22):19072-19077
Mitchell CJ; Kelly MM; Blewitt M; Wilson JR; Biden TJ
Phospholipase C-gamma mediates the hydrolysis of phosphatidylinositol, but not of phosphatidylinositol 4,5- bisphoshate, in carbamylcholine-stimulated islets of langerhans
20
155 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(22):19469-19482
Sapkota GP; Kieloch A; Lizcano JM; Lain S; Arthur JSC; Williams MR; Morrice N; Deak M; Alessi DR
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser(431) by p90(RSK) and cAMP- dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell growth
83
156 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(27):24531-24539
Gineitis D; Treisman R
Differential usage of signal transduction pathways defines two types of serum response factor target gene
51
157 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(32):29719-29728
Matassa AA; Carpenters L; Biden TJ; Humphries MJ; Reyland ME
PKC delta is required for mitochondrial-dependent apoptosis in salivary epithelial cells
72
158 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(34):32214-32219
Peiretti F; Lopez S; Deprez-Beauclair P; Bonardo B; Juhan-Vague I; Nalbone G
Inhibition of p70(S6) kinase during transforming growth factor- beta 1/vitamin D-3-induced monocyte differentiation of HL-60 cells allows tumor necrosis factor-alpha to stimulate plasminogen activator inhibitor-1 synthesis
10
159 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(35):32552-32558
Yu CF; Roshan B; Liu ZX; Cantley LG
ERK regulates the hepatocyte growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase
62
160 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(35):32670-32677
Wang LJ; Gout I; Proud CG
Cross-talk between the ERK and p70 S6 kinase (S6K) signaling pathways - MEK-dependent activation of S6K2 in cardiomyocytes
 0
161 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(37):34473-34479
Geddis AE; Fox NE; Kaushansky K
Phosphatidylinositol 3-kinase is necessary but not sufficient for thrombopoietin-induced proliferation in engineered Mp1- bearing cell lines as well as in primary megakaryocytic progenitors
30
262 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(41):37986-37992
Soltoff SP
Rottlerin is a mitochondrial uncoupler that decreases cellular ATP levels and indirectly blocks protein kinase C delta tyrosine phosphorylation
61
163 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(41):38052-38060
Tremblay F; Marette A
Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway - A negative feedback mechanism leading to insulin resistance in skeletal muscle cells
 0
164 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(45):41879-41888
LaRochelle O; Gagne V; Charron J; Soh JW; Seguin C
Phosphorylation is involved in the activation of metal- regulatory transcription factor 1 in response to metal ions
10
165 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(48):45041-45050
Martin MC; Dransfield I; Haslett C; Rossi AG
Cyclic AMP regulation of neutrophil apoptosis occurs via a novel protein kinase A-independent signaling pathway
10
266 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(49):46079-46087
Somwar R; Niu W; Kim DY; Sweeney G; Randhawa VK; Huang C; Ramlal T; Klip A
Differential effects of phosphatidylinositol 3-kinase inhibition on intracellular signals regulating GLUT4 translocation and glucose transport
10
167 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(52):48693-48701
Caivano M; Gorgoni B; Cohen P; Poli V
The induction of cyclooxygenase-2 mRNA in macrophages is biphasic and requires both CCAAT enhancer-binding protein beta (C/EBP beta) and C/EBP delta transcription factors
20
168 2001 JOURNAL OF BONE AND MINERAL RESEARCH 16(11):2050-2056
Mathov I; Plotkin LI; Sgarlata CL; Leoni J; Bellido T
Extracellular signal-regulated kinases and calcium channels are involved in the proliferative effect of bisphosphonates on osteoblastic cells in vitro
 0
169 2001 JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 21(8):887-906
Laher I; Zhang JH
Protein kinase C and cerebral vasospasm
 0
170 2001 JOURNAL OF CLINICAL INVESTIGATION 108(6):851-859
Milella M; Kornblau SM; Estrov Z; Carter BZ; Lapillonne H; Harris D; Konopleva M; Zhao SR; Estey E; Andreeff M
Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia.
21
371 2001 JOURNAL OF ENDOCRINOLOGY 171(3):R11-R15
Lewitt MS; Brismar K; Ohlson J; Hartman J
Lithium chloride inhibits the expression and secretion of insulin-like growth factor-binding protein-1
 0
172 2001 JOURNAL OF HYPERTENSION 19(3):599-602
Semplicini A; Ceolotto G; Baritono E; Malendowicz LK; Andreis PG; Sartori M; Rossi GP; Nussdorfer GG
Adrenomedullin stimulates DNA synthesis of rat adrenal zona glomerulosa cells through activation of the mitogen-activated protein kinase-dependent cascade
50
173 2001 JOURNAL OF INVESTIGATIVE MEDICINE 49(6):566-571
Tobiasch E; Gunther L; Bach FH
Heme oxygenase-1 protects pancreatic beta cells from apoptosis caused by various stimuli
 0
174 2001 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 33(10):1773-1776
Clerk A
Death by protein kinase C inhibitor: a stressful event
40
175 2001 JOURNAL OF NEUROCHEMISTRY 77(1):94-102
Cross DAE; Culbert AA; Chalmers KA; Facci L; Skaper SD; Reith AD
Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death
104
176 2001 JOURNAL OF NEUROCHEMISTRY 78(3):490-498
Bobrovskaya L; Odell A; Leal RB; Dunkley PR
Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation
20
177 2001 JOURNAL OF NEUROCHEMISTRY 78(6):1219-1232
Grimes CA; Jope RS
CREB DNA binding activity is inhibited by glycogen synthase kinase-3 beta and facilitated by lithium
21
178 2001 JOURNAL OF NEUROCHEMISTRY 79(1):25-34
Hisaoka K; Nishida A; Koda T; Miyata M; Zensho H; Morinobu S; Ohta M; Yamawaki S
Antidepressant drug treatments induce glial cell line-derived neurotrophic factor (GDNF) synthesis and release in rat C6 glioblastoma cells
 0
179 2001 JOURNAL OF NEUROCHEMISTRY 79(4):767-776
Mikkelsen SE; Novitskaya V; Kriajevska M; Berezin V; Bock E; Norrild B; Lukanidin E
S100A12 protein is a strong inducer of neurite outgrowth from primary hippocampal neurons
 0
180 2001 JOURNAL OF NEUROCHEMISTRY 79(6):1136-1148
Berti-Mattera LN; Harwalkar S; Hughes B; Wilkins PL; Almhanna K
Proliferative and morphological effects of endothelins in Schwann cells: roles of p38 mitogen-activated protein kinase and Ca2+-independent phospholipase A(2)
 0
181 2001 JOURNAL OF NEUROCHEMISTRY 79(6):1149-1160
Jessen U; Novitskaya V; Pedersen N; Serup P; Berezin V; Bock E
The transcription factors CREB and c-Fos play key roles in NCAM-mediated neuritogenesis in PC12-E2 cells
 0
182 2001 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 298(2):825-832
Hsu EH; Lochan AC; Cowen D
Activation of Akt1 by human 5-hydroxytryptamine (serotonin)(1B) receptors is sensitive to inhibitors of MEK
10
183 2001 MOLECULAR AND CELLULAR BIOLOGY 21(7):2423-2434
Chiloeches A; Mason CS; Marais R
S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3
111
184 2001 MOLECULAR AND CELLULAR BIOLOGY 21(24):8671-8683
Tang H; Hornstein E; Stolovich M; Levy G; Livingstone M; Templeton D; Avruch J; Meyuhas O
Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin and is independent of S6K1 and rpS6 phosphorylation
10
185 2001 MOLECULAR AND CELLULAR NEUROSCIENCE 18(5):512-524
Berkeley JL; Gomeza J; Wess J; Hamilton SE; Nathanson NM; Levey AI
M-1 muscarinic acetylcholine receptors activate extracellular signal-regulated kinase in CA1 pyramidal neurons in mouse hippocampal slices
 0
186 2001 MOLECULAR CELL 8(3):601-611
Desagher S; Osen-Sand A; Montessuit S; Magnenat E; Vilbois F; Hochmann A; Journot L; Antonsson B; Martinou JC
Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8
100
187 2001 MOLECULAR CELL 8(6):1231-1241
Thomson S; Clayton AL; Mahadevan LC
Independent dynamic regulation of histone phosphorylation and acetylation during immediate-early gene induction
31
188 2001 MOLECULAR ENDOCRINOLOGY 15(7):1211-1221
Scholze A; Plant TD; Dolphin AC; Nurnberg B
Functional expression and characterization of a voltage-gated Ca(v)1,3 (alpha(1D)) calcium channel subunit from an insulin- secreting cell line
10
189 2001 MOLECULAR ENDOCRINOLOGY 15(9):1559-1570
Trumper A; Trumper K; Trusheim H; Arnold R; Goke B; Horsch D
Glucose-dependent insulinotropic polypeptide is a growth factor for beta (INS-1) cells by pleiotropic signaling
 0
190 2001 NATURE 413(6858):794-795
Niswender KD; Morton GJ; Stearns WH; Rhodes CJ; Myers MG; Schwartz MW
Intracellular signalling - Key enzyme in leptin-induced anorexia
60
191 2001 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 364(5):444-453
Ponicke K; Schluter KD; Heinroth-Hoffmann I; Seyfarth T; Goldberg M; Osten B; Piper HM; Brodde OE
Noradrenaline-induced increase in protein synthesis in adult rat cardiomyocytes: involvement of only alpha(1A)-adrenoceptors
10
192 2001 ONCOGENE 20(34):4696-4709
Crepieux P; Marion S; Martinat N; Fafeur V; Le Vern Y; Kerboeuf D; Guillou F; Reiter E
The ERK-dependent signalling is stage-specifically modulated by FSH, during primary Sertoli cell maturation
20
193 2001 ONCOGENE 20(42):5941-5950
Riley D; Carragher N; Frame MC; Wyke JA
The mechanism of cell cycle regulation by v-Src
20
194 2001 PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 442(3):391-395
Straube S; Parekh AB
Effects of phosphatidylinositol kinase inhibitors on the activation of the store-operated calcium current I-CRAC in RBL- 1 cells
 0
295 2001 PROGRESS IN NEUROBIOLOGY 65(4):391-426
Grimes CA; Jope RS
The multifaceted roles of glycogen synthase kinase 3 beta in cellular signaling
100
196 2001 TERATOLOGY 63(5):193-201
Wentzel P; Wentzel CR; Gareskog MB; Eriksson UJ
Induction of embryonic dysmorphogenesis by high glucose concentration, disturbed inositol metabolism, and inhibited protein kinase C activity
10
197 2002 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 282(6):C1432-C1444
Wu SS; Chiu T; Rozengurt E
ANG II and LPA induce Pyk2 tyrosine phosphorylation in intestinal epithelial cells: role of Ca2+, PKC, and Rho kinase
 0
198 2002 AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 282(6):E1214-E1221
Fisher JS; Nolte LA; Kawanaka K; Han DH; Jones TE; Holloszy JO
Glucose transport rate and glycogen synthase activity both limit skeletal muscle glycogen accumulation
 0
299 2002 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 397(2):224-231
Haydon CE; Watt PW; Morrice N; Knebel A; Gaestel M; Cohen P
Identification of a phosphorylation site on skeletal muscle myosin light chain kinase that becomes phosphorylated during muscle contraction
 0
1100 2002 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 22(3):394-399
Luo HL; Reidy MA
Activation of big mitogen-activated protein kinase-1 regulates smooth muscle cell replication
 0
1101 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 290(1):552-557
Sliva D; English D; Lyons D; Lloyd FP
Protein kinase C induces motility of breast cancers by upregulating secretion of urokinase-type plasminogen activator through activation of AP-1 and NF-kappa B
 0
1102 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 293(1):446-450
Wilson WJ; Poellinger L
The dietary flavonoid quercetin modulates HIF-1 alpha activity in endothelial cells
 0
1103 2002 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1586(1):113-122
Martin CP; Vazquez J; Avila J; Moreno FJ
P24, a glycogen synthase kinase 3 (GSK 3) inhibitor
 0
1104 2002 BLOOD 99(1):151-158
Yap CL; Anderson KE; Hughan SC; Dopheide SM; Salem HH; Jackson SP
Essential role for phosphoinositide 3-kinase in shear-dependent signaling between platelet glycoprotein Ib/V/IX and integrin alpha(IIb)beta(3)
 0
1105 2002 BLOOD 99(6):2060-2069
Kanthou C; Tozer GM
The tumor vascular targeting agent combretastatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells
 0
1106 2002 BLOOD 99(8):2969-2976
Barragan M; Iosillo BB; Campas C; Colomer D; Pons G; Gil J
Involvement of protein kinase C and phosphatidylinositol 3- kinase pathways in the survival of B-cell chronic lymphocytic leukemia cells
 0
2107 2002 BLOOD 99(9):3461-3464
Milella M; Estrov Z; Kornblau SM; Carter BZ; Konopleva M; Tari A; Schober WD; Harris D; Leysath CE; Lopez-Berestein G; Huang ZW; Andreeff M
Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia
 0
1108 2002 CARDIOVASCULAR RESEARCH 53(1):219-226
McGregor E; Gosling M; Beattie DK; Ribbons DMP; Davies AH; Powell JT
Circumferential stretching of saphenous vein smooth muscle enhances vasoconstrictor responses by Rho kinase-dependent pathways
 0
2109 2002 CELLULAR SIGNALLING 14(2):109-113
Schulte G; Fredholm BB
Diverse inhibitors of intracellular signalling act as adenosine receptor antagonists
 0
2110 2002 CIRCULATION 105(13):1545-1547
Masumoto A; Mohri M; Shimokawa H; Urakami L; Usui M; Takeshita A
Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina
10
1111 2002 CLINICAL & EXPERIMENTAL METASTASIS 19(1):79-85
Denkert C; Siegert A; Leclere A; Turzynski A; Hauptmann S
An inhibitor of stress-activated MAP-kinases reduces invasion and MMP-2 expression of malignant melanoma cells
 0
1112 2002 DEVELOPMENT 129(7):1681-1691
del Corral RD; Breitkreuz DN; Storey KG
Onset of neuronal differentiation is regulated by paraxial mesoderm and requires attenuation of FGF signalling
 0
2113 2002 DIABETES 51(2):317-324
Carpenter L; Cordery D; Biden TJ
Inhibition of protein kinase C delta protects rat INS-1 cells against interleukin-1 beta and streptozotocin-induced apoptosis
 0
1114 2002 DIABETES 51(3):631-637
Mei J; Holst LS; Landstrom TR; Holm C; Brindley D; Manganiello V; Degerman E
C-2-ceramide influences the expression and insulin-mediated regulation of cyclic nucleotide phosphodiesterase 3B and lipolysis in 3T3-L1 adipocytes
 0
1115 2002 EMBO JOURNAL 21(4):736-748
Muller JM; Metzger E; Greschik H; Bosserhoff AK; Mercep L; Buettner R; Schule R
The transcriptional coactivator FHL2 transmits Rho signals from the cell membrane into the nucleus
 0
1116 2002 ENDOCRINOLOGY 143(4):1512-1520
Keembiyehetty CN; Candelaria RP; Majumdar G; Raghow R; Martinez-Hernandez A; Solomon SS
Paradoxical regulation of Sp1 transcription factor by glucagon
 0
2117 2002 ENDOCRINOLOGY 143(6):2303-2313
Chepurny OG; Hussain MA; Holz GG
Exendin-4 as a stimulator of rat insulin I gene promoter activity via bZIP/CRE interactions sensitive to serine/threonine protein kinase inhibitor Ro 31-8220
 0
1118 2002 EXPERIMENTAL CELL RESEARCH 275(1):1-8
Zakany R; Szucs K; Bako E; Felszeghy S; Czifra G; Biro T; Modis L; Gergely P
Protein phosphatase 2A is involved in the regulation of protein kinase A signaling pathway during in vitro chondrogenesis
 0
1119 2002 EXPERIMENTAL NEUROLOGY 175(1):245-256
Zhang J; Suneja SK; Potashner SJ
Protein kinase C regulates [H-3]D-aspartate release in auditory brain stem nuclei
 0
2120 2002 FEBS LETTERS 510(3):149-153
Llorens F; Garcia L; Itarte E; Gomez N
Apigenin and LY294002 prolong EGF-stimulated ERK1/2 activation in PC12 cells but are unable to induce full differentiation
 0
1121 2002 FEBS LETTERS 516(1-3):151-155
Delobel P; Flament S; Hamdane M; Delacourte A; Vilain JP; Buee L
Modelling Alzheimer-specific abnormal Tau phosphorylation independently of GSK3 beta and PKA kinase activities
 0
1122 2002 FEBS LETTERS 519(1-3):135-140
Marmy-Conus N; Hannan KM; Pearson RB
Ro 31-6045, the inactive analogue of the protein kinase C inhibitor Ro 31-8220, blocks in vivo activation of p70(s6k)/p85(s6k): implications for the analysis of S6K signalling
 0
1123 2002 FREE RADICAL BIOLOGY AND MEDICINE 32(7):650-662
Sekhar KR; Spitz DR; Harris S; Nguyen TT; Meredith MJ; Holt JT; Guis D; Marnett LJ; Summar ML; Freeman ML
Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase
 0
1124 2002 FRONTIERS IN BIOSCIENCE 7():D904-D917
Jiang GQ; Zhang BB
PI 3-kinase and its up- and down-stream modulators as potential targets for the treatment of type II diabetes
 0
1125 2002 HYPERTENSION 39(2):399-404
Stawowy P; Blaschke F; Kilimnik A; Goetze S; Kallisch H; Chretien M; Marcinkiewicz M; Fleck E; Graf K
Proprotein convertase PC5 regulation by PDGF-BB involves PI3- kinase/p70(s6)-kinase activation in vascular smooth muscle cells
 0
1126 2002 HYPERTENSION 39(2):412-417
Dubey RK; Gillespie DG; Zacharia LC; Rosselli M; Imthurn B; Jackson EK
Methoxyestradiols mediate the antimitogenic effects of locally applied estradiol on cardiac fibroblast growth
 0
1127 2002 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 9(6):563-570
Kaartinen V; Haataja L; Nagy A; Heisterkamp N; Groffen J
TGF beta 3-induced activation of RhoA/Rho-kinase pathway is necessary but not sufficient for epithelio-mesenchymal transdifferentiation: Implications for palatogenesis
 0
1128 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(2):1340-1348
Bruce JIE; Shuttleworth TJ; Giovannucci DR; Yule DI
Phosphorylation of inositol 1,4,5-trisphosphate receptors in parotid acinar cells - A mechanism for the synergistic effects of cAMP on Ca2+ signaling
 0
1129 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(3):1669-1679
Walters MR; Dutertre M; Smith CL
SKF-82958 is a subtype-selective estrogen receptor-alpha (ER alpha) agonist that induces functional interactions between ER alpha and AP-1
 0
1130 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(3):1728-1738
Fagerholm S; Morrice N; Gahmberg CG; Cohen P
Phosphorylation of the cytoplasmic domain of the integrin CD18 chain by protein kinase C isoforms in leukocytes
 0
2131 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(10):8741-8748
Kelemen BR; Hsiao K; Goueli SA
Selective in vivo inhibition of mitogen-activated protein kinase activation using cell-permeable peptides
 0
2132 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(12):10452-10458
Liu ZX; Yu CF; Nickel C; Thomas S; Cantley LG
Hepatocyte growth factor induces ERK-dependent paxillin phosphorylation and regulates paxillin-focal adhesion kinase association
 0
2133 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(13):11591-11596
Herbert TP; Tee AR; Proud CG
The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites
10
1134 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(14):12456-12462
Delehedde M; Lyon M; Vidyasagar R; McDonnell TJ; Fernig DG
Hepatocyte growth factor/scatter factor binds to small heparin- derived oligosaccharides and stimulates the proliferation of human HaCaT keratinocytes
 0
1135 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(16):13508-13517
Alvarez-Tejado M; Alfranca A; Aragones J; Vara A; Landazuri MO; del Peso L
Lack of evidence for the involvement of the phosphoinositide 3- kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension
 0
1136 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(20):17448-17456
Carl VS; Brown-Steinke K; Nicklin MJH; Smith MF
Toll-like receptor 2 and 4 (TLR2 and TLR4) agonists differentially regulate secretory interleukin-1 receptor antagonist gene expression in macrophages
 0
2137 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(22):19382-19388
Yu CF; Liu ZX; Cantley LG
ERK negatively regulates the epidermal growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase
 0
2138 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(22):19876-19881
Kunzelmann-Marche C; Freyssinet JM; Martinez MC
Loss of plasma membrane phospholipid asymmetry requires raft integrity - Role of transient receptor potential channels and ERK pathway
 0
2139 2002 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 39(3):319-327
Shimokawa H
Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases
 0
1140 2002 JOURNAL OF CELLULAR PHYSIOLOGY 191(3):351-361
Tangkijvanich P; Santiskulvong C; Melton AC; Rozengurt E; Yee HF
p38 MAP kinase mediates platelet-derived growth factor- stimulated migration of hepatic myofibroblasts
 0
1141 2002 JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 22(4):444-452
Mori T; Wang XY; Jung TC; Sumii T; Singhal AB; Fini ME; Dixon CE; Alessandrini A; Lo EH
Mitogen-activated protein kinase inhibition in traumatic brain injury: In vitro and in vivo effects
10
1142 2002 JOURNAL OF IMMUNOLOGY 168(9):4519-4523
von Essen M; Menne C; Nielsen BL; Lauritsen JPH; Dietrich J; Andersen PS; Karjalainen K; Odum N; Geisler C
The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation
 0
1143 2002 JOURNAL OF IMMUNOLOGY 168(10):5342-5351
Waetzig GH; Seegert D; Rosenstiel P; Nikolaus S; Schreiber S
p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease
 0
1144 2002 JOURNAL OF MEDICINAL CHEMISTRY 45(8):1712-1722
McGovern SL; Caselli E; Grigorieff N; Shoichet BK
A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening
 0
1145 2002 JOURNAL OF MOLECULAR ENDOCRINOLOGY 28(1):45-51
Bolander FF
Prolactin activation of mammary nitric oxide synthase: molecular mechanisms
 0
1146 2002 JOURNAL OF NEUROCHEMISTRY 81(3):472-480
Bull ND; Barnett NL
Antagonists of protein kinase C inhibit rat retinal glutamate transport activity in situ
 0
1147 2002 JOURNAL OF NEUROSCIENCE 22(9):art. no.-RC220
Chin J; Angers A; Cleary LJ; Eskin A; Byrne JH
Transforming growth factor beta 1 alters synapsin distribution and modulates synaptic depression in aplysia
 0
1148 2002 JOURNAL OF NEUROSCIENCE 22(5):1738-1751
Anantharam V; Kitazawa M; Wagner J; Kaul S; Kanthasamy AG
Caspase-3-dependent proteolytic cleavage of protein kinase C delta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl
 0
1149 2002 JOURNAL OF NEUROSCIENCE 22(11):4335-4345
Coffey ET; Smiciene G; Hongisto V; Cao J; Brecht S; Herdegen T; Courtney MJ
c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons
 0
1150 2002 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 300(3):1000-1007
Leemhuis J; Boutillier S; Schmidt G; Meyer DK
The protein kinase A inhibitor H89 acts on cell morphology by inhibiting rho kinase
 0
1151 2002 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 13(6):1481-1489
Ward DT; McLarnon SJ; Riccardi D
Aminoglycosides increase intracellular calcium levels and ERK activity in proximal tubular OK cells expressing the extracellular calcium-sensing receptor
 0
1152 2002 MOLECULAR AND CELLULAR BIOLOGY 22(1):117-126
Wurster AL; Withers DJ; Uchida T; White MF; Grusby MJ
Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4- dependent rescue from apoptosis
 0
1153 2002 MOLECULAR AND CELLULAR BIOLOGY 22(1):182-195
Blass M; Kronfeld I; Kazimirsky G; Blumberg PM; Brodie C
Tyrosine phosphorylation of protein kinase C delta is essential for its apoptotic effect in response to etoposide
10
1154 2002 MOLECULAR AND CELLULAR BIOLOGY 22(8):2799-2809
Shioi T; McMullen JR; Kang PM; Douglas PS; Obata T; Franke TF; Cantley LC; Izumo S
Akt/Protein kinase B promotes organ growth in transgenic mice
 0
3155 2002 MOLECULAR AND CELLULAR BIOLOGY 22(8):2871-2881
Wiggin GR; Soloaga A; Foster JM; Murray-Tait V; Cohen P; Arthur JSC
MSK1 and MSK2 are required for the mitogen-and stress-induced phosphorylation of CREB and ATF1 in fibroblasts
 0
2156 2002 MOLECULAR PSYCHIATRY 7():S35-S45
Jope RS; Bijur GN
Mood stabilizers, glycogen synthase kinase-3 beta and cell survival
 0
2157 2002 NATURE REVIEWS MOLECULAR CELL BIOLOGY 3(1):30-40
Hazzalin CA; Mahadevan LC
MAPK-regulated transcription: A continuously variable gene switch?
30
1158 2002 NEUROBIOLOGY OF DISEASE 9(1):38-48
Nuydens R; Van Den Kieboom G; Nolten C; Verhulst C; Van Osta P; Spittaels K; Van den Haute C; De Feyter E; Geerts H; Van Leuven F
Coexpression of GSK-3 beta corrects phenotypic aberrations of dorsal root ganglion cells, cultured from adult transgenic mice overexpressing human protein tau
 0
1159 2002 NEUROPHARMACOLOGY 42(1):9-19
Pereira DB; Carvalho AP; Duarte CB
Non-specific effects of the MEK inhibitors PD098,059 and U0126 on glutamate release from hippocampal synaptosomes
 0
1160 2002 NEUROPHARMACOLOGY 42(2):221-228
Boyd DF; Mathie A
Inhibition of the potassium current IKso, in cerebellar granule cells, by the inhibitors of MEK1 activation, PD 98059 and U 0126
 0
1161 2002 ONCOGENE 21(5):778-788
Saavedra AP; Tsygankova OM; Prendergast GV; Dworet JH; Cheng G; Meinkoth JL
Role of cAMP, PKA and Rap1A in thyroid follicular cell survival
 0
2162 2002 ONCOGENE 21(7):1071-1078
Zhong MH; Lu ZM; Foster DA
Downregulating PKC delta provides a PI3K/Akt-independent survival signal that overcomes apoptotic signals generated by c-Src overexpression
 0
1163 2002 ONCOGENE 21(11):1727-1738
Sato S; Fujita N; Tsuruo T
Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine)
 0
1164 2002 PHARMACOLOGY 64(4):189-195
Tokuyama K; Nishimura H; Iizuka K; Kato M; Arakawa H; Saga R; Mochizuki H; Morikawa A
Effects of Y-27632, a Rho/Rho kinase inhibitor, on leukotriene D-4- and histamine-induced airflow obstruction and airway microvascular leakage in guinea pigs in vivo
 0
1165 2002 TRAFFIC 3(6):428-439
Korolchuk VI; Banting G
CK2 and GAK/auxilin2 are major protein kinases in clathrin- coated vesicles
 0
2166 2002 TRENDS IN PHARMACOLOGICAL SCIENCES 23(1):40-45
English JM; Cobb MH
Pharmacological inhibitors of MAPK pathways
 0

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