| Cited nodes | Nodes / Authors | GCS | LCS |
| 1 | 1 2000 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1529(1-3):114-125
Schoonjans K; Brendel C; Mangelsdorf D; Auwerx J
Sterols and gene expression: control of affluence | 5 | 1
|
| 1 | 2 2000 CURRENT OPINION IN LIPIDOLOGY 11(6):627-637
von Eckardstein A; Assmann G
Prevention of coronary heart disease by raising high-density lipoprotein cholesterol? | 13 | 0
|
| 2 | 3 2000 GENES & DEVELOPMENT 14(22):2819-2830
Repa JJ; Liang GS; Ou JF; Bashmakov Y; Lobaccaro JMA; Shimomura I; Shan B; Brown MS; Goldstein JL; Mangelsdorf DJ
Regulation of mouse sterol regulatory element-binding protein- 1c gene (SREBP-1c) by oxysterol receptors, LXR alpha and LXR beta | 70 | 31
|
| 2 | 4 2000 GENES & DEVELOPMENT 14(22):2831-2838
Schultz JR; Tu H; Luk A; Repa JJ; Medina JC; Li LP; Schwendner S; Wang S; Thoolen M; Mangelsdorf DJ; Lustig KD; Shan B
Role of LXRs in control of lipogenesis | 53 | 32
|
| 0 | 5 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(36):28240-28245
Costet P; Luo Y; Wang N; Tall AR
Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor | 99 | 99
|
| 1 | 6 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(40):30794-30800
Chen WG; Silver DL; Smith JD; Tall AR
Scavenger receptor-BI inhibits ATP-binding cassette transporter 1-mediated cholesterol efflux in macrophages | 20 | 8
|
| 1 | 7 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(42):33053-33058
Wang N; Silver DL; Costet P; Tall AR
Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1 | 62 | 26
|
| 1 | 8 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(44):34508-34511
Oram JF; Lawn RM; Garvin MR; Wade DP
ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages | 56 | 26
|
| 1 | 9 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(48):37324-37332
Shiffman D; Mikita T; Tai JTN; Wade DP; Porter JG; Seilhamer JJ; Somogyi R; Liang SD; Lawn RM
Large scale gene expression analysis of cholesterol-loaded macrophages | 18 | 2
|
| 1 | 10 2000 JOURNAL OF CLINICAL INVESTIGATION 106(10):1205-1207
Tall AR; Wang N
Tangier disease as a test of the reverse cholesterol transport hypothesis | 17 | 7
|
| 1 | 11 2000 M S-MEDECINE SCIENCES 16(12):1456-1458
Lambert G; Sinal CJ
Nuclear receptors LXR and FXR control cholesterol and bile acid metabolism | 0 | 0
|
| 1 | 12 2000 NATURE MEDICINE 6(10):1104-1105
Tall AR; Costet P; Luo Y
'Orphans' meet cholesterol | 4 | 1
|
| 2 | 13 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(6):1161-1177
Hegele RA
Monogenic dyslipidemias: Window on determinants of plasma lipoprotein metabolism | 1 | 0
|
| 3 | 14 2001 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 21(1):13-27
von Eckardstein A; Nofer JR; Assmann G
High density lipoproteins and arteriosclerosis - Role of cholesterol efflux and reverse cholesterol transport | 27 | 0
|
| 3 | 15 2001 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 21(3):378-385
Lawn RM; Wade DP; Couse TL; Wilcox JN
Localization of human ATP-binding cassette transporter 1 (ABC1) in normal and atherosclerotic tissues | 14 | 5
|
| 1 | 16 2001 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 21(8):1320-1326
Cheung MC; Zhao XQ; Chait A; Albers JJ; Brown BG
Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL | 9 | 0
|
| 1 | 17 2001 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 21(12):1876-1890
Hansson GK
Immune mechanisms in atherosclerosis | 4 | 0
|
| 4 | 18 2001 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 21(12):2019-2025
Huang ZH; Lin CY; Oram JF; Mazzone T
Sterol efflux mediated by endogenous macrophage ApoE expression is independent of ABCA1 | 2 | 1
|
| 0 | 19 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 283(3):590-597
Bellincampi L; Simone ML; Motti C; Cortese C; Bernardini S; Bertolini S; Calandra S
Identification of an alternative transcript of ABCA1 gene in different human cell types | 1 | 0
|
| 3 | 20 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 283(5):1019-1025
Tanaka AR; Ikeda Y; Abe-Dohmae S; Arakawa R; Sadanami K; Kidera A; Nakagawa S; Nagase T; Aoki R; Kioka N; Amachi T; Yokoyama S; Ueda K
Human ABCA1 contains a large amino-terminal extracellular domain homologous to an epitope of Sjogren's syndrome | 3 | 0
|
| 1 | 21 2001 BIOCHEMISTRY 40(31):9363-9373
Gaus K; Gooding JJ; Dean RT; Kritharides L; Jessup W
A kinetic model to evaluate cholesterol efflux from THP-1 macrophages to apolipoprotein a-1 | 1 | 0
|
| 2 | 22 2001 BIOCHEMISTRY 40(43):13002-13014
Gaus K; Dean RT; Kritharides L; Jessup W
Inhibition of cholesterol efflux by 7-ketocholesterol: Comparison between cells, plasma membrane vesicles, and liposomes as cholesterol donors | 2 | 0
|
| 1 | 23 2001 CANCER RESEARCH 61(23):8534-8539
Kolluri SK; Balduf C; Hofmann M; Gottlicher M
Novel target genes of the Ah (dioxin) receptor: Transcriptional induction of N-myristoyltransferase 2 | 0 | 0
|
| 5 | 24 2001 CELL 104(4):503-516
Glass CK; Witztum JL
Atherosclerosis: The road ahead | 48 | 5
|
| 3 | 25 2001 CIRCULATION 104(20):2498-2502
Shah PK; Kaul S; Nilsson J; Cercek B
Exploiting the vascular protective effects of high-density lipoprotein and its apolipoproteins - An idea whose time for testing is coming, Part II | 1 | 0
|
| 2 | 26 2001 CLINICAL CHEMISTRY 47(12):2089-2097
Kielar D; Dietmaier W; Langmann T; Aslanidis C; Probst M; Naruszewicz M; Schmitz G
Rapid quantification of human ABCA1 mRNA in various cell types and tissues by real-time reverse transcription-PCR | 1 | 1
|
| 5 | 27 2001 CURRENT OPINION IN LIPIDOLOGY 12(2):113-120
Fayard E; Schoonjans K; Auwerx J
Xol INXS: role of the liver X and the farnesol X receptors | 4 | 3
|
| 4 | 28 2001 CURRENT OPINION IN LIPIDOLOGY 12(2):129-140
Schmitz G; Langmann T
Structure, function and regulation of the ABC1 gene product | 16 | 4
|
| 1 | 29 2001 CURRENT OPINION IN LIPIDOLOGY 12(3):355-356
Davidson J; Rotondo D
Lipid metabolism | 0 | 0
|
| 1 | 30 2001 CYTOGENETICS AND CELL GENETICS 92(3-4):264-270
Broccardo C; Osorio J; Luciani MF; Schriml LM; Prades C; Shulenin S; Arnould I; Naudin L; Lafargue C; Rosier M; Jordan B; Mattei M; Dean M; Denefle P; Chimini G
Comparative analysis of the promoter structure and genomic organization of the human and mouse ABCA7 gene encoding a novel ABCA transporter | 0 | 0
|
| 2 | 31 2001 DIABETES 50(8):1851-1856
Tu AY; Albers JJ
Glucose regulates the transcription of human genes relevant to HDL metabolism - Responsive elements for peroxisome proliferator-activated receptor are involved in the regulation of phospholipid transfer protein | 2 | 0
|
| 6 | 32 2001 EXPERT OPINION ON INVESTIGATIONAL DRUGS 10(3):427-438
Oram JF
Novel approaches to treating cardiovascular disease: lessons from Tangier disease | 3 | 1
|
| 8 | 33 2001 EXPERT OPINION ON INVESTIGATIONAL DRUGS 10(11):1901-1911
Best JD; Jenkins AJ
Novel agents for managing dyslipidaemia | 0 | 0
|
| 1 | 34 2001 GENE 262(1-2):257-265
Chiang JYL; Kimmel R; Stroup D
Regulation of cholesterol 7 alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXR alpha) | 15 | 7
|
| 1 | 35 2001 GENOMICS 73(1):66-76
Qiu Y; Cavelier L; Chiu S; Yang XL; Rubin E; Cheng JF
Human and mouse ABCA1 comparative sequencing and transgenesis studies revealing novel regulatory sequences | 5 | 1
|
| 1 | 36 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(2):974-983
Zhang YQ; Yin LY; Hillgartner FB
Thyroid hormone stimulates acetyl-CoA carboxylase-alpha transcription in hepatocytes by modulating the composition of nuclear receptor complexes bound to a thyroid hormone response element | 3 | 0
|
| 2 | 37 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(15):12427-12433
Porsch-Ozcurumez M; Langmann T; Heimerl S; Borsukova H; Kaminski WE; Drobnik W; Honer C; Schumacher C; Schmitz G
The zinc finger protein 202 (ZNF202) is a transcriptional repressor of ATP binding cassette transporter A1 (ABCA1) and ABCG1 gene expression and a modulator of cellular lipid efflux | 10 | 0
|
| 3 | 38 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(18):15137-15145
Fitzgerald ML; Mendez AJ; Moore KJ; Andersson LP; Panjeton HA; Freeman MW
ATP-binding cassette transporter A1 contains an NH2-terminal signal anchor sequence that translocates the protein's first hydrophilic domain to the exoplasmic space | 11 | 6
|
| 1 | 39 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(20):16904-16910
Le Lay S; Krief S; Farnier C; Lefrere I; Le Liepvre X; Bazin R; Ferre P; Dugail I
Cholesterol, a cell size-dependent signal that regulates glucose metabolism and gene expression in adipocytes | 5 | 0
|
| 3 | 40 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(21):18046-18051
Cavelier LB; Qiu Y; Bielicki JK; Afzal V; Cheng JF; Rubin EM
Regulation and activity of the human ABCA1 gene in transgenic mice | 13 | 10
|
| 5 | 41 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(27):24767-24773
Luo Y; Liang CP; Tall AR
The orphan nuclear receptor LRH-1 potentiates the sterol- mediated induction of the human CETP gene by liver X receptor | 3 | 2
|
| 3 | 42 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(36):33969-33979
Singaraja RR; Bocher V; James ER; Clee SM; Zhang LH; Leavitt BR; Tan B; Brooks-Wilson A; Kwok A; Bissada N; Yang YZ; Liu GQ; Tafuri SR; Fievet C; Wellington CL; Staels B; Hayden MR
Human ABCA1 BAC transgenic mice show increased high density lipoprotein cholesterol and apoAI-dependent efflux stimulated by an internal promoter containing liver X receptor response elements in intron 1 | 12 | 7
|
| 8 | 43 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(41):37735-37738
Lu TT; Repa JJ; Mangelsdorf DJ
Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism | 20 | 5
|
| 5 | 44 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(42):38378-38387
Fu X; Menke JG; Chen YL; Zhou GC; MacNaul KL; Wright SD; Sparrow CP; Lund EG
27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells | 11 | 10
|
| 3 | 45 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(42):39438-39447
Kennedy MA; Venkateswaran A; Tarr PT; Xenarios I; Kudoh J; Shimizu N; Edwards PA
Characterization of the human ABCG1 gene - Liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein | 6 | 4
|
| 7 | 46 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(46):43018-43024
Zhang Y; Repa JJ; Gauthier K; Mangelsdorf DJ
Regulation of lipoprotein lipase by the oxysterol receptors, LXR alpha and LXR beta | 5 | 4
|
| 8 | 47 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(47):43509-43515
Whitney KD; Watson MA; Goodwin B; Galardi CM; Maglich JM; Wilson JG; Willson TM; Collins JL; Kliewer SA
Liver X receptor (LXR) regulation of the LMR alpha gene in human macrophages | 4 | 2
|
| 5 | 48 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(47):43564-43569
Chen W; Sun Y; Welch C; Gorelik A; Leventhal AR; Tabas I; Tall AR
Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes | 3 | 2
|
| 6 | 49 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(49):45729-45739
Mikita T; Porter G; Lawn RM; Shiffman D
Oxidized low density lipoprotein exposure alters the transcriptional response of macrophages to inflammatory stimulus | 1 | 0
|
| 2 | 50 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(52):48702-48708
Gan XD; Kaplan R; Menke JG; MacNaul K; Chen YL; Sparrow CP; Zhou GH; Wright SD; Cai TQ
Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate | 3 | 2
|
| 1 | 51 2001 JOURNAL OF CLINICAL INVESTIGATION 107(5):565-573
Alberti S; Schuster G; Parini P; Feltkamp D; Diczfalusy U; Rudling M; Angelin B; Bjorkhem I; Pettersson S; Gustafsson JA
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXR beta-deficient mice | 11 | 7
|
| 6 | 52 2001 JOURNAL OF CLINICAL INVESTIGATION 108(9):1273-1275
Tall AR; Wang N; Mucksavage P
Is it time to modify the reverse cholesterol transport model? | 2 | 1
|
| 2 | 53 2001 JOURNAL OF LIPID RESEARCH 42(5):856-863
Panousis CG; Evans G; Zuckerman SH
TGF-beta increases cholesterol efflux and ABC-1 expression in macrophage-derived foam cells: opposing the effects of IFN- lambda | 4 | 2
|
| 9 | 54 2001 JOURNAL OF LIPID RESEARCH 42(8):1173-1179
Oram JF; Lawn RM
ABCA1: the gatekeeper for eliminating excess tissue cholesterol | 15 | 7
|
| 8 | 55 2001 JOURNAL OF LIPID RESEARCH 42(9):1339-1345
Santamarina-Fojo S; Remaley AT; Neufeld EB; Brewer HB
Regulation and intracellular trafficking of the ABCA1 transporter | 9 | 0
|
| 1 | 56 2001 JOURNAL OF MEDICINAL CHEMISTRY 44(6):886-897
Spencer TA; Li DS; Russel JS; Collins JL; Bledsoe RK; Consler TG; Moore LB; Galardi CM; McKee DD; Moore JT; Watson MA; Parks DJ; Lambert MH; Willson TM
Pharmacophore analysis of the nuclear oxysterol receptor LXR alpha | 9 | 6
|
| 1 | 57 2001 JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY 45(5):S158-S167
Staels B
Regulation of lipid and lipoprotein metabolism by retinoids | 0 | 0
|
| 3 | 58 2001 LANCET 357(9251):161-163
Wade DP; Owen JS
Regulation of the cholesterol efflux gene, ABCA1 | 5 | 1
|
| 1 | 59 2001 METABOLISM-CLINICAL AND EXPERIMENTAL 50(9):1106-1112
Xu GR; Salen G; Shefer S; Tint GS; Nguyen LB; Batta AK; Pcolinsky M
Plant stanol fatty acid esters inhibit cholesterol absorption and hepatic hydroxymethyl glutaryl coenzyme A reductase activity to reduce plasma levels in rabbits | 0 | 0
|
| 3 | 60 2001 MOLECULAR AND CELLULAR BIOLOGY 21(9):2991-3000
Yoshikawa T; Shimano H; Amemiya-Kudo M; Yahagi N; Hasty AH; Matsuzaka T; Okazaki K; Tamura Y; Iizuka Y; Ohashi K; Osuga JI; Harada K; Gotoda T; Kimura S; Ishibashi S; Yamada N
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter | 16 | 8
|
| 8 | 61 2001 MOLECULAR AND CELLULAR BIOLOGY 21(22):7558-7568
Laffitte BA; Joseph SB; Walczak R; Pei LM; Wilpitz DC; Collins JL; Tontonoz P
Autoregulation of the human liver X receptor alpha promoter | 9 | 8
|
| 1 | 62 2001 MOLECULAR CELL 7(1):161-171
Chawla A; Boisvert WA; Lee CH; Laffitte BA; Barak Y; Joseph SB; Liao D; Nagy L; Edwards PA; Curtiss LK; Evans RM; Tontonoz P
A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis | 60 | 22
|
| 1 | 63 2001 NATURE MEDICINE 7(1):53-58
Chinetti G; Lestavel S; Bocher V; Remaley AT; Neve B; Torra IP; Teissier E; Minnich A; Jaye M; Duverger N; Brewer HB; Fruchart JC; Clavey V; Staels B
PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway | 73 | 18
|
| 2 | 64 2001 NATURE REVIEWS MOLECULAR CELL BIOLOGY 2(9):657-668
Ioannou YA
Multidrug permeases and subcellular cholesterol transport | 6 | 0
|
| 1 | 65 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(2):507-512
Laffitte BA; Repa JJ; Joseph SB; Wilpiltz DC; Kast HR; Mangelsdorf DJ; Tontonoz P
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes | 34 | 26
|
| 1 | 66 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(5):2610-2615
Claudel T; Leibowitz MD; Fievet C; Tailleux A; Wagner B; Repa JJ; Torpier G; Lobaccaro JM; Paterniti JR; Mangelsdorf DJ; Heyman RA; Auwerx J
Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor | 26 | 13
|
| 4 | 67 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(9):5306-5311
Oliver WR; Shenk JL; Snaith MR; Russell CS; Plunket KD; Bodkin NL; Lewis MC; Winegar DA; Sznaidman ML; Lambert MH; Xu HE; Sternbach DD; Kliewer SA; Hansen BC; Willson TM
A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport | 39 | 13
|
| 3 | 68 2001 PROGRESS IN LIPID RESEARCH 40(6):439-452
Shimano H
Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes | 0 | 0
|
| 11 | 69 2001 SCIENCE 294(5548):1866-1870
Chawla A; Repa JJ; Evans RM; Mangelsdorf DJ
Nuclear receptors and lipid physiology: Opening the X-files | 18 | 1
|
| 1 | 70 2001 STEROIDS 66(6):473-479
Song C; Hiipakka RA; Liao SS
Auto-oxidized cholesterol sulfates are antagonistic ligands of liver X receptors: implications for the development and treatment of atherosclerosis | 1 | 1
|
| 5 | 71 2001 STEROIDS 66(9):673-681
Song C; Liao SS
Hypolipidemic effects of selective liver X receptor alpha agonists | 0 | 0
|
| 2 | 72 2001 TETRAHEDRON 57(39):8291-8296
Zhou XD; Zhou WS
A new highly stereoselective synthesis of cerebrosterol, an agonist of the nuclear receptor LXRs | 0 | 0
|
| 4 | 73 2002 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 22(5):E5-E9
Wang XQ; Panousis CG; Alfaro ML; Evans GF; Zuckerman SH
Interferon-gamma-mediated downregulation of cholesterol efflux and ABC1 expression is by the Stat1 pathway | 0 | 0
|
| 6 | 74 2002 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 22(1):127-132
Liao HL; Langmann T; Schmitz G; Zhu Y
Native LDL upregulation of ATP-binding cassette transporter-1 in human vascular endothelial cells | 0 | 0
|
| 12 | 75 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 290(2):663-669
Lin GR; Bornfeldt KE
Cyclic AMP-specific phosphodiesterase 4 inhibitors promote ABCA1 expression and cholesterol efflux | 1 | 0
|
| 6 | 76 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 290(5):1376-1381
Stein O; Ben-Naim M; Dabach Y; Hollander G; Stein Y
Macrophage cholesterol efflux to free apoprotein A-I in C3H and C57BL/6 mice | 0 | 0
|
| 2 | 77 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 292(5):1147-1153
Javitt NB
Cholesterol, hydroxycholesterols, and bile acids | 0 | 0
|
| 6 | 78 2002 BIOCHEMICAL JOURNAL 364():475-484
Lee J; Shirk A; Oram JF; Lee SP; Kuver R
Polarized cholesterol and phospholipid efflux in cultured gall- bladder epithelial cells: evidence for an ABCA1-mediated pathway | 0 | 0
|
| 9 | 79 2002 CURRENT OPINION IN LIPIDOLOGY 13(3):247-253
Bjorkhem I; Meaney S; Diczfalusy U
Oxysterols in human circulation: which role do they have? | 0 | 0
|
| 11 | 80 2002 DRUG NEWS & PERSPECTIVES 15(1):24-28
Oram JE
ABCA1 as a new therapeutic target for treating cardiovascular disease | 0 | 0
|
| 7 | 81 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(7):4713-4721
Landis MS; Patel HV; Capone JP
Oxysterol activators of liver X receptor and 9-cis-retinoic acid promote sequential steps in the synthesis and secretion of tumor necrosis factor-alpha from human monocytes | 0 | 0
|
| 7 | 82 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(7):5692-5697
Wang YT; Oram JF
Unsaturated fatty acids inhibit cholesterol efflux from macrophages by increasing degradation of ATP-binding cassette transporter A1 | 3 | 2
|
| 5 | 83 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(12):10021-10027
Sparrow CP; Baffic J; Lam MH; Lund EG; Adams AD; Fu XA; Hayes N; Jones AB; Macnaul KL; Ondeyka J; Singh S; Wang JH; Zhou GC; Moller DE; Wright SD; Menke JG
A potent synthetic LXR agonist is more effective than cholesterol loading at inducing ABCA1 mRNA and stimulating cholesterol efflux | 1 | 0
|
| 6 | 84 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(13):11019-11025
Joseph SB; Laffitte BA; Patel PH; Watson MA; Matsukuma KE; Walczak R; Collins JL; Osborne TF; Tontonoz P
Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors | 2 | 1
|
| 9 | 85 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(17):14443-14450
Langmann T; Porsch-Ozcurumez M; Heimerl S; Probst M; Moehle C; Taher M; Borsukova H; Kielar D; Kaminski WE; Dittrich-Wengenroth E; Schmitz G
Identification of sterol-independent regulatory elements in the human ATP-binding cassette transporter A1 promoter - Role of Sp1/3, E-box binding factors, and an oncostatin M-responsive element | 0 | 0
|
| 8 | 86 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(21):18793-18800
Repa JJ; Berge KE; Pomajzl C; Richardson JA; Hobbs H; Mangelsdorf DJ
Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta | 0 | 0
|
| 3 | 87 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(25):22426-22429
Arakawa R; Yokoyama S
Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation | 0 | 0
|
| 19 | 88 2002 JOURNAL OF HEPATOLOGY 36(6):832-850
Karpen SJ
Nuclear receptor regulation of hepatic function | 0 | 0
|
| 3 | 89 2002 JOURNAL OF INVESTIGATIVE DERMATOLOGY 118(1):25-34
Komuves LG; Schmuth M; Fowler AJ; Elias PM; Hanley K; Man MQ; Moser AH; Lobaccaro JMA; Williams ML; Mangelsdorf DJ; Feingold KR
Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis | 0 | 0
|
| 13 | 90 2002 JOURNAL OF LIPID RESEARCH 43(1):2-12
Edwards PA; Kast HR; Anisfeld AM
BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis | 2 | 1
|
| 6 | 91 2002 JOURNAL OF LIPID RESEARCH 43(2):177-186
Walczak R; Tontonoz P
PPARadigms and PPARadoxes: expanding roles for PPAR gamma in the control of lipid metabolism | 1 | 1
|
| 9 | 92 2002 JOURNAL OF LIPID RESEARCH 43(2):297-306
Yang XP; Freeman LA; Knapper CL; Amar MJA; Remaley A; Brewer HB; Santamarina-Fojo S
The E-box motif in the proximal ABCA1 promoter mediates transcriptional repression of the ABCA1 gene | 0 | 0
|
| 2 | 93 2002 JOURNAL OF LIPID RESEARCH 43(4):533-543
Davis RA; Miyake JH; Hui TY; Spann NJ
Regulation of cholesterol-7 alpha-hydroxylase: BAREly missing a SHP | 0 | 0
|
| 7 | 94 2002 JOURNAL OF LIPID RESEARCH 43(6):952-959
Kaplan R; Gan XD; Menke JG; Wright SD; Cai TQ
Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway | 0 | 0
|
| 6 | 95 2002 JOURNAL OF MEDICINAL CHEMISTRY 45(10):1963-1966
Collins JL; Fivush AM; Watson MA; Galardi CM; Lewis MC; Moore LB; Parks DJ; Wilson JG; Tippin TK; Binz JG; Plunket KD; Morgan DG; Beaudet EJ; Whitney KD; Kliewer SA; Willson TM
Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines | 0 | 0
|
| 7 | 96 2002 JOURNAL OF MOLECULAR MEDICINE-JMM 80(5):271-281
Fitzgerald ML; Moore KJ; Freeman MW
Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home | 0 | 0
|
| 5 | 97 2002 LABORATORY INVESTIGATION 82(3):273-283
Wellington CL; Walker EKY; Suarez A; Kwok A; Bissada N; Singaraja R; Yang YZ; Zhang LH; James E; Wilson JE; Francone O; McManus BM; Hayden MR
ABCA1 mRNA and protein distribution patterns predict multiple different roles and levels of regulation | 0 | 0
|
| 6 | 98 2002 MOLECULAR AND CELLULAR BIOLOGY 22(8):2607-2619
Akiyama TE; Sakai S; Lambert G; Nicol CJ; Matsusue K; Pimprale S; Lee YH; Ricote M; Glass CK; Brewer HB; Gonzalez FJ
Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux | 2 | 0
|
| 7 | 99 2002 MOLECULAR ENDOCRINOLOGY 16(3):506-514
Li Y; Bolten C; Bhat BG; Woodring-Dietz J; Li SZ; Prayaga SK; Xia CS; Lala DS
Induction of human liver X receptor alpha gene expression via an autoregulatory loop mechanism | 2 | 1
|
| 8 | 100 2002 MOLECULAR ENDOCRINOLOGY 16(6):1378-1385
Whitney KD; Watson MA; Collins JL; Benson WG; Stone TM; Numerick MJ; Tippin TK; Wilson JG; Winegar DA; Kliewer SA
Regulation of cholesterol Homeostasis by the liver X receptors in the central nervous system | 0 | 0
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| 5 | 101 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(1):407-412
Joyce CW; Amar MJA; Lambert G; Vaisman BL; Paigen B; Najib-Fruchart J; Hoyt RF; Neufeld ED; Remaley AT; Fredrickson DS; Brewer HB; Santamarina-Fojo S
The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE- knockout mice | 3 | 0
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| 11 | 102 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(11):7604-7609
Joseph SB; McKilligin E; Pei LM; Watson MA; Collins AR; Laffitte BA; Chen MY; Noh G; Goodman J; Hagger GN; Tran J; Tippin TK; Wang XP; Lusis AJ; Hsueh WA; Law RE; Collins JL; Willson TM; Tontonoz P
Synthetic LXR ligand inhibits the development of atherosclerosis in mice | 0 | 0
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| 13 | 103 2002 TRENDS IN CARDIOVASCULAR MEDICINE 12(4):170-175
Oram JF
The cholesterol mobilizing transporter ABCA1 as a new therapeutic target for cardiovascular disease | 0 | 0
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| 17 | 104 2002 TRENDS IN MOLECULAR MEDICINE 8(4):168-173
Oram JF
Molecular basis of cholesterol homeostasis: lessons from Tangier disease and ABCA1 | 0 | 0
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