| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 1 | 1 | 1 2001 CELL 106(2):183-194
Osherovich LZ; Weissman JS
Multiple GIn/Asn-rich prion domains confer susceptibility to induction of the yeast [PSI+] prion | 14 | 1
|
| 2 | 1 | 2 2001 DRUGS & AGING 18(9):685-716
Halliwell B
Role of free radicals in the neurodegenerative diseases - Therapeutic implications for antioxidant treatment | 19 | 2
|
| 3 | 1 | 3 2001 EMBO REPORTS 2(12):1133-1138
Murata S; Minami Y; Minami M; Chiba T; Tanaka K
CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein | 16 | 4
|
| 4 | 1 | 4 2001 FUNCTIONAL NEUROLOGY 16(4):17-30
Govoni S; Lanni C; Racchi M
Advances in understanding the pathogenetic mechanisms of Alzheimer's disease | 0 | 0
|
| 5 | 1 | 5 2001 GENES & DEVELOPMENT 15(20):2660-2674
Swanson R; Locher M; Hochstrasser M
A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER- associated and Mat alpha 2 repressor degradation | 14 | 1
|
| 6 | 1 | 6 2001 HUMAN MOLECULAR GENETICS 10(18):1963-1970
Kurihara LJ; Kikuchi T; Wada K; Tilghman SM
Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia | 7 | 3
|
| 7 | 1 | 7 2001 HUMAN MOLECULAR GENETICS 10(22):2569-2579
Zander C; Takahashi J; El Hachimi KH; Fujigasaki H; Albanese V; Lebre AS; Stevanin G; Duyckaerts C; Brice A
Similarities between spinocerebellar ataxia type 7 (SCA7) cell models and human brain: proteins recruited in inclusions and activation of caspase-3 | 2 | 0
|
| 8 | 1 | 8 2001 IMMUNOLOGIC RESEARCH 24(3):245-272
Hwang LY; Lieu PT; Peterson PA; Yang Y
Functional regulation of immunoproteasomes and transporter associated with antigen processing | 0 | 0
|
| 9 | 1 | 9 2001 IUBMB LIFE 52(6):303-307
Arrigo AP
Hsp27: Novel regulator of intracellular redox state | 2 | 0
|
| 10 | 1 | 10 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(48):44889-44897
Chai YH; Wu LZ; Griffin JD; Paulson HL
The role of protein composition in specifying nuclear inclusion formation in polyglutamine disease | 7 | 2
|
| 11 | 1 | 11 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(49):46073-46078
Tsirigotis M; Zhang M; Chiu RK; Wouters BG; Gray DA
Sensitivity of mammalian cells expressing mutant ubiquitin to protein-damaging agents | 3 | 1
|
| 12 | 1 | 12 2001 JOURNAL OF HUMAN GENETICS 46(11):609-618
Shastry BS
Molecular and cell biological aspects of Alzheimer disease | 3 | 0
|
| 13 | 1 | 13 2001 JOURNAL OF NEUROSCIENCE 21(22):8772-8781
Martin-Aparicio E; Yamamoto A; Hernandez F; Hen R; Avila JS; Lucas JJ
Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease | 9 | 0
|
| 14 | 1 | 14 2001 M S-MEDECINE SCIENCES 17(11):1149-1157
Lebre AS; Brice A
Polyglutamine expansion diseases: molecular and pathophysiological data | 0 | 0
|
| 15 | 1 | 15 2001 MOLECULAR CELL 8(6):1339-1349
Navon A; Goldberg AL
Proteins are unfolded on the surface of the ATPase ring before transport into the proteasome | 18 | 7
|
| 16 | 1 | 16 2001 NATURE REVIEWS NEUROSCIENCE 2(7):492-501
Goedert M
Alpha-synuclein and neurodegenerative diseases | 42 | 2
|
| 17 | 1 | 17 2001 NEUROREPORT 12(15):3263-3267
Thomas T; Nadackal TG; Thomas K
Aspirin and non-steroidal anti-inflammatory drugs inhibit amyloid-beta aggregation | 2 | 0
|
| 18 | 1 | 18 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(21):11955-11960
Bevivino AE; Loll PJ
An expanded glutamine repeat destabilizes native ataxin-3 structure and mediates parallel beta-fibrils | 6 | 2
|
| 19 | 0 | 19 2001 SCIENCE 292(5521):1552-1555
Bence NF; Sampat RM; Kopito RR
Impairment of the ubiquitin-proteasome system by protein aggregation | 138 | 138
|
| 20 | 2 | 20 2001 SCIENCE 293(5528):224-225
Haass C; Kahle PJ
Neuroscience - Parkin and its substrates | 6 | 1
|
| 21 | 1 | 21 2001 SCIENCE 293(5528):263-269
Shimura H; Schlossmacher MC; Hattori N; Frosch MP; Trockenbacher A; Schneider R; Mizuno Y; Kosik KS; Selkoe DJ
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implications for Parkinson's disease | 117 | 19
|
| 22 | 1 | 22 2001 TRENDS IN MOLECULAR MEDICINE 7(11):479-482
Margolis RL; Ross CA
Expansion explosion: new clues to the pathogenesis of repeat expansion neurodegenerative diseases | 7 | 2
|
| 23 | 2 | 23 2001 TRENDS IN NEUROSCIENCES 24(11):S7-S14
Chung KKK; Dawson VL; Dawson TM
The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders | 12 | 2
|
| 24 | 1 | 24 2002 AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 283(4):L849-L858
Araya J; Maruyama M; Inoue A; Fujita T; Kawahara J; Sassa K; Hayashi R; Kawagishi Y; Yamashita N; Sugiyama E; Kobayashi M
Inhibition of proteasome activity is involved in cobalt-induced apoptosis of human alveolar macrophages | 0 | 0
|
| 25 | 1 | 25 2002 AMERICAN JOURNAL OF THE MEDICAL SCIENCES 324(2):84-95
Vicioso BA
Dementia: When is it not Alzheimer disease? | 0 | 0
|
| 26 | 2 | 26 2002 ANNALS OF NEUROLOGY 51(6):779-782
Furukawa Y; Vigouroux S; Wong H; Guttman M; Rajput AH; Ang L; Briand M; Kish SJ; Briand Y
Brain proteasomal function in sporadic Parkinson's disease and related disorders | 0 | 0
|
| 27 | 1 | 27 2002 ANNUAL REVIEW OF BIOMEDICAL ENGINEERING 4():155-174
Murphy RM
Peptide aggregation in neurodegenerative disease | 1 | 0
|
| 28 | 1 | 28 2002 ANTIOXIDANTS & REDOX SIGNALING 4(3):415-425
Matsuzawa A; Nishitoh H; Tobiume K; Takeda K; Ichijo H
Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: Advanced findings from ASK1 knockout mice | 0 | 0
|
| 29 | 1 | 29 2002 BIOCHIMIE 84(4):273-278
Hoffner G; Djian P
Protein aggregation in Huntington's disease | 0 | 0
|
| 30 | 1 | 30 2002 BRAIN RESEARCH 956(1):156-165
Meredith GE; Totterdell S; Petroske E; Cruz KS; Callison RC; Lau YS
Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease | 0 | 0
|
| 31 | 1 | 31 2002 BRITISH MEDICAL JOURNAL 324(7352):1467-1468
Golbe LI
Neurodegeneration in the age of molecular biology - Abnormal protein folding holds the key to specific treatment | 0 | 0
|
| 32 | 1 | 32 2002 CELL 108(4):513-521
Carmo-Fonseca M
The contribution of nuclear compartmentalization to gene regulation | 13 | 0
|
| 33 | 2 | 33 2002 CELL 111(2):209-218
Liu YC; Fallon L; Lashuel HA; Liu ZH; Lansbury PT
The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility | 2 | 1
|
| 34 | 1 | 34 2002 CELL MOTILITY AND THE CYTOSKELETON 53(1):26-38
Johnston JA; Illing ME; Kopito RR
Cytoplasmic dynein/dynactin mediates the assembly of aggresomes | 0 | 0
|
| 35 | 1 | 35 2002 CELL STRESS & CHAPERONES 7(2):186-190
Soti C; Csermely P
Chaperones come of age | 1 | 0
|
| 36 | 1 | 36 2002 CELLULAR AND MOLECULAR MECHANISMS OF DRUGS OF ABUSE II: COCAINE, SUBSTITUTED AMPHETAMINES, GHB, AND OPIATES 965():381-398
Fornai F; Gesi M; Lenzi P; Ferrucci M; Pellegrini A; Ruggieri S; Casini A; Paparelli A
Striatal postsynaptic ultrastructural alterations following methylenedioxymethamphetamine administration | 0 | 0
|
| 37 | 1 | 37 2002 CURRENT OPINION IN CELL BIOLOGY 14(1):110-122
Coulombe PA; Omary MB
'Hard' and 'soft' principles defining the structure, function and regulation of keratin intermediate filaments | 17 | 1
|
| 38 | 2 | 38 2002 DEVELOPMENTAL CELL 2(2):143-151
Osherovich LZ; Weissman JS
The utility of prions | 3 | 0
|
| 39 | 2 | 39 2002 DEVELOPMENTAL NEUROSCIENCE 24(2-3):114-124
Drake SK; Bourdon E; Wehr NB; Levine RL; Backlund PS; Yergey AL; Rouault TA
Numerous proteins in mammalian cells are prone to iron- dependent oxidation and proteasomal degradation | 0 | 0
|
| 40 | 1 | 40 2002 EUROPEAN JOURNAL OF NEUROSCIENCE 15(3):419-428
Snider BJ; Lee LY; Canzoniero LMT; Babcock DJ; Choi DW
NMDA antagonists exacerbate neuronal death caused by proteasome inhibition in cultured cortical and striatal neurons | 0 | 0
|
| 41 | 3 | 41 2002 EUROPEAN JOURNAL OF NEUROSCIENCE 16(11):2136-2148
McNaught KSP; Shashidharan P; Perl DP; Jenner P; Olanow CW
Aggresome-related biogenesis of Lewy bodies | 0 | 0
|
| 42 | 1 | 42 2002 EXPERIMENTAL AND MOLECULAR PATHOLOGY 73(2):75-83
Bardag-Gorce F; van Leeuwen FW; Nguyen V; French BA; Li J; Riley N; McPhaul LW; Lue YH; French SW
The role of the ubiquitin-proteasome pathway in the formation of Mallory bodies | 0 | 0
|
| 43 | 2 | 43 2002 EXPERIMENTAL NEUROLOGY 177(1):88-94
Sakamoto M; Uchihara T; Hayashi M; Nakamura A; Kikuchi E; Mizutani T; Mizusawa H; Hirai S
Heterogeneity of nigral and cortical Lewy bodies differentiated by amplified triple-labeling for alpha-synuclein, ubiquitin, and thiazin red | 0 | 0
|
| 44 | 1 | 44 2002 FEBS LETTERS 515(1-3):61-65
Chun W; Lesort M; Lee M; Johnson GVW
Mutant huntingtin aggregates do not sensitize cells to apoptotic stressors | 0 | 0
|
| 45 | 3 | 45 2002 FEBS LETTERS 529(1):22-26
Dantuma NP; Masucci MG
Stabilization signals: a novel regulatory mechanism in the ubiquitin/proteasome system | 0 | 0
|
| 46 | 1 | 46 2002 FISH & SHELLFISH IMMUNOLOGY 12(4):335-351
Okubo K; Yamano K; Qin QW; Aoyagi K; Ototake M; Nakanishi T; Fukuda H; Dijkstra JM
Ubiquitin genes in rainbow trout (Oncorhynchus mykiss) | 1 | 0
|
| 47 | 2 | 47 2002 GENES & DEVELOPMENT 16(11):1307-1313
Yoneda T; Urano F; Ron D
Transmission of proteotoxicity across cellular compartments | 0 | 0
|
| 48 | 1 | 48 2002 GENES & DEVELOPMENT 16(11):1345-1355
Nishitoh H; Matsuzawa A; Tobiume K; Saegusa K; Takeda K; Inoue K; Hori S; Kakizuka A; Ichijo H
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats | 14 | 4
|
| 49 | 2 | 49 2002 HEPATOLOGY 35(2):251-257
Omary MB; Ku NO; Toivola DM
Keratins: Guardians of the liver | 4 | 0
|
| 50 | 1 | 50 2002 HEPATOLOGY 35(5):1053-1062
Stumptner C; Fuchsbichler A; Heid H; Zatloukal K; Denk H
Mallory body - A disease-associated type of sequestosome | 1 | 0
|
| 51 | 1 | 51 2002 HISTOCHEMISTRY AND CELL BIOLOGY 117(1):41-53
Hirano K; Roth J; Zuber C; Ziak M
Expression of a mutant ER-retained polytope membrane protein in cultured rat hepatocytes results in Mallory body formation | 2 | 0
|
| 52 | 1 | 52 2002 HISTOLOGY AND HISTOPATHOLOGY 17(3):897-908
Larsen KE; Sulzer D
Autophagy in neurons: a review | 3 | 0
|
| 53 | 1 | 53 2002 HUMAN MOLECULAR GENETICS 11(5):515-523
Bailey CK; Andriola IFM; Kampinga HH; Merry DE
Molecular chaperones enhance the degradation of expanded polyglutamine repeat androgen receptor in a cellular model of spinal and bulbar muscular atrophy | 8 | 3
|
| 54 | 1 | 54 2002 HUMAN MOLECULAR GENETICS 11(9):1107-1117
Ravikumar B; Duden R; Rubinsztein DC
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy | 3 | 0
|
| 55 | 1 | 55 2002 HUMAN MOLECULAR GENETICS 11(9):1137-1151
Wyttenbach A; Sauvageot O; Carmichael J; Diaz-Latoud C; Arrigo AP; Rubinsztein DC
Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin | 3 | 0
|
| 56 | 1 | 56 2002 HUMAN MOLECULAR GENETICS 11(11):1251-1262
Ganesh S; Delgado-Escueta AV; Sakamoto T; Avila MR; Machado-Salas J; Hoshii Y; Akagi T; Gomi H; Suzuki T; Amano K; Agarwala KL; Hasegawa Y; Bai DS; Ishihara T; Hashikawa T; Itohara S; Cornford EM; Niki H; Yamakawa K
Targeted disruption of the Epm2a gene causes formation of Lafora inclusion bodies, neurodegeneration, ataxia, myoclonus epilepsy and impaired behavioral response in mice | 0 | 0
|
| 57 | 1 | 57 2002 HUMAN MOLECULAR GENETICS 11(21):2657-2672
Kazemi-Esfarjani P; Benzer S
Suppression of polyglutamine toxicity by a Drosophila homolog of myeloid leukemia factor 1 | 0 | 0
|
| 58 | 4 | 58 2002 HUMAN MOLECULAR GENETICS 11(22):2689-2700
Verhoef LGGC; Lindsten K; Masucci MG; Dantuma NP
Aggregate formation inhibits proteasomal degradation of polyglutamine proteins | 0 | 0
|
| 59 | 1 | 59 2002 JOURNAL OF BIOCHEMISTRY 131(5):647-651
Suzuki T; Nakagawa M; Yoshikawa A; Sasagawa N; Yoshimori T; Ohsumi Y; Nishino I; Ishiura S; Nonaka I
The first molecular evidence that autophagy relates rimmed vacuole formation in chloroquine myopathy | 1 | 0
|
| 60 | 1 | 60 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(3):1872-1877
Kim SH; Creemers JWM; Chu S; Thinakaran G; Sisodia SS
Proteolytic processing of familial British dementia-associated BRI variants - Evidence for enhanced intracellular accumulation of amyloidogenic peptides | 2 | 0
|
| 61 | 1 | 61 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(14):11709-11714
Gelman MS; Kannegaard ES; Kopito RR
A principal role for the proteasome in endoplasmic reticulum- associated degradation of misfolded intracellular cystic fibrosis transmembrane conductance regulator | 5 | 1
|
| 62 | 1 | 62 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(16):13935-13942
Ding QX; Lewis JJ; Strum KM; Dimayuga E; Bruce-Keller AJ; Dunn JC; Keller JN
Polyglutamine expansion, protein aggregation, proteasome activity, and neural survival | 5 | 3
|
| 63 | 1 | 63 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(28):25283-25289
Figueiredo-Pereira ME; Li ZM; Jansen M; Rockwell P
N-acetylcysteine and celecoxib lessen cadmium cytotoxicity which is associated with cyclooxygenase-2 up-regulation in mouse neuronal cells | 0 | 0
|
| 64 | 3 | 64 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(32):28572-28577
Hyun DH; Lee M; Hattori N; Kubo SI; Mizuno Y; Halliwell B; Jenner P
Effect of wild-type or mutant parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome | 1 | 0
|
| 65 | 1 | 65 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(37):34150-34160
Illing ME; Rajan RS; Bence NF; Kopito RR
A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system | 0 | 0
|
| 66 | 1 | 66 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(37):34462-34470
Milewski MI; Mickle JE; Forrest JK; Stanton BA; Cutting GR
Aggregation of misfolded proteins can be a selective process dependent upon peptide composition | 0 | 0
|
| 67 | 3 | 67 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(39):36793-36798
Niwa J; Ishigaki S; Hishikawa N; Yamamoto M; Doyu M; Murata S; Tanaka K; Taniguchi N; Sobue G
Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1- mediated neurotoxicity | 2 | 0
|
| 68 | 2 | 68 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(49):47358-47365
Kobayashi T; Tanaka K; Inoue K; Kakizuka A
Functional ATPase activity of p97/valosin-containing protein (VCP) is required for the quality control of endoplasmic reticulum in neuronally differentiated mammalian PC12 cells | 0 | 0
|
| 69 | 2 | 69 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(50):48984-48992
Gosavi N; Lee HJ; Lee JS; Patel S; Lee SJ
Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion | 1 | 0
|
| 70 | 1 | 70 2002 JOURNAL OF CELL BIOLOGY 157(3):381-394
VanSlyke JK; Musil LS
Dislocation and degradation from the ER are regulated by cytosolic stress | 5 | 0
|
| 71 | 2 | 71 2002 JOURNAL OF CELL BIOLOGY 157(3):417-427
Lindsten K; de Vrij FMS; Verhoef LGGC; Fischer DF; van Leeuwen FW; Hol EM; Masucci MG; Dantuma NP
Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation | 4 | 2
|
| 72 | 1 | 72 2002 JOURNAL OF CELL BIOLOGY 158(2):247-257
Molinari M; Galli C; Piccaluga V; Pieren M; Paganetti P
Sequential assistance of molecular chaperones and transient formation of covalent complexes during protein degradation from the ER | 1 | 0
|
| 73 | 1 | 73 2002 JOURNAL OF CELL SCIENCE 115(14):2907-2918
Saliba RS; Munro PMG; Luthert PJ; Cheetham ME
The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation | 1 | 0
|
| 74 | 1 | 74 2002 JOURNAL OF CELL SCIENCE 115(14):3007-3014
Lenk U; Yu H; Walter J; Gelman MS; Hartmann E; Kopito RR; Sommer T
A role for mammalian Ubc6 homologues in ER-associated protein degradation | 1 | 0
|
| 75 | 2 | 75 2002 JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 6(1):25-48
Wojcik C
Regulation of apoptosis by the ubiquitin and proteasome pathway | 1 | 0
|
| 76 | 1 | 76 2002 JOURNAL OF CLINICAL INVESTIGATION 110(9):1221-1232
Horwich A
Protein aggregation in disease: a role for folding intermediates forming specific multimeric interactions | 2 | 1
|
| 77 | 3 | 77 2002 JOURNAL OF CLINICAL INVESTIGATION 110(10):1389-1398
Kaufman RJ
Orchestrating the unfolded protein response in health and disease | 1 | 0
|
| 78 | 1 | 78 2002 JOURNAL OF NEUROCHEMISTRY 82(3):449-457
Kahle PJ; Haass C; Kretzschmar HA; Neumann M
Structure/function of alpha-synuclein in health and disease: rational development of animal models for Parkinson's and related diseases | 0 | 0
|
| 79 | 1 | 79 2002 JOURNAL OF NEUROCHEMISTRY 82(4):819-827
Namekata K; Nishimura N; Kimura H
Presenilin-binding protein forms aggresomes in monkey kidney COS-7 cells | 0 | 0
|
| 80 | 1 | 80 2002 JOURNAL OF NEUROCHEMISTRY 82(5):1229-1238
Lee JP; Gerin C; Bindokas VP; Miller R; Ghadge G; Roos RP
No correlation between aggregates of Cu/Zn superoxide dismutase and cell death in familial amyotrophic lateral sclerosis | 0 | 0
|
| 81 | 2 | 81 2002 JOURNAL OF NEUROCHEMISTRY 83(1):176-185
David DC; Layfield R; Serpell L; Narain Y; Goedert M; Spillantini MG
Proteasomal degradation of tau protein | 1 | 0
|
| 82 | 3 | 82 2002 JOURNAL OF NEUROCHEMISTRY 83(2):360-370
Hyun DH; Lee MH; Halliwell B; Jenner P
Proteasomal dysfunction induced by 4-hydroxy-2,3-trans-nonenal, an end-product of lipid peroxidation: a mechanism contributing to neurodegeneration? | 0 | 0
|
| 83 | 1 | 83 2002 JOURNAL OF NEUROCHEMISTRY 83(5):1030-1042
Urushitani M; Kurisu J; Tsukita K; Takahashi R
Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis | 0 | 0
|
| 84 | 3 | 84 2002 JOURNAL OF NEUROSCIENCE 22(24):10690-10698
Ryu EJ; Harding HP; Angelastro JM; Vitolo OV; Ron D; Greene LA
Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease | 0 | 0
|
| 85 | 1 | 85 2002 JOURNAL OF NEUROSCIENCE RESEARCH 70(5):645-654
Baracskay KL; Duchala CS; Miller RH; Macklin WB; Trapp BD
Oligodendrogenesis is differentially regulated in gray and white matter of jimpy mice | 0 | 0
|
| 86 | 3 | 86 2002 LANCET 359(9325):2242-2247
Davis RL; Shrimpton AE; Carrell RW; Lomas DA; Gerhard L; Baumann B; Lawrence DA; Yepes M; Kim TS; Ghetti B; Piccardo P; Takao M; Lacbawan F; Muenke M; Sifers RN; Bradshaw CB; Kent PF; Collins GH; Larocca D; Holohan PD
Association between conformational mutations in neuroserpin and onset and severity of dementia | 3 | 0
|
| 87 | 1 | 87 2002 MITOCHONDRIAL FUNCTION AND DYSFUNCTION 53():315-339
Petersen A; Brundin P
Huntington's disease: The mystery unfolds? | 0 | 0
|
| 88 | 3 | 88 2002 MOLECULAR AND CELLULAR NEUROSCIENCE 21(2):223-238
Rideout HJ; Stefanis L
Proteasomal inhibition-induced inclusion formation and death in cortical neurons require transcription and ubiquitination | 1 | 0
|
| 89 | 1 | 89 2002 MOLECULAR BIOLOGY OF THE CELL 13(8):2771-2782
Lafarga M; Berciano MT; Pena E; Mayo I; Castano JG; Bohmann D; Rodrigues JP; Tavanez JP; Carmo-Fonseca M
Clastosome: A subtype of nuclear body enriched in 19S and 20S proteasomes, ubiquitin, and protein substrates of proteasome | 0 | 0
|
| 90 | 1 | 90 2002 MOLECULAR BIOLOGY OF THE CELL 13(10):3441-3451
Nakamichi I; Hatakeyama S; Nakayama KI
Formation of Mallory body-like inclusions and cell death induced by deregulated expression of keratin 18 | 0 | 0
|
| 91 | 1 | 91 2002 MOLECULAR CELL 10(2):259-269
Lunkes A; Lindenberg KS; Ben-Haiem L; Weber C; Devys D; Landwehrmeyer GB; Mandel JL; Trottier Y
Proteases acting on mutant Huntingtin generate cleaved products that differentially build up cytoplasmic and nuclear inclusions | 5 | 2
|
| 92 | 1 | 92 2002 MOLECULAR GENETICS AND METABOLISM 77(1-2):44-56
Sakamoto KM
Ubiquitin-dependent proteolysis: its role in human diseases and the design of therapeutic strategies | 0 | 0
|
| 93 | 1 | 93 2002 MOLECULAR IMMUNOLOGY 39(3-4):171-179
Kessler BM; Glas R; Ploegh HL
MHC class I antigen processing regulated by cytosolic proteolysis - short cuts that alter peptide generation | 0 | 0
|
| 94 | 1 | 94 2002 NATURE 417(6885):177-182
Lelouard H; Gatti E; Cappello F; Gresser O; Camosseto V; Pierre P
Transient aggregation of ubiquitinated proteins during dendritic cell maturation | 2 | 0
|
| 95 | 1 | 95 2002 NATURE CELL BIOLOGY 4(3):240-245
Peters PJ; Ning K; Palacios F; Boshans RL; Kazantsev A; Thompson LM; Woodman B; Bates GP; D'Souza-Schorey C
Arfaptin 2 regulates the aggregation of mutant huntingtin protein | 2 | 0
|
| 96 | 2 | 96 2002 NATURE REVIEWS NEUROSCIENCE 3(12):932-942
Lotharius J; Brundin P
Pathogenesis of Parkinson's disease: Dopamine, vesicles and alpha-synuclein | 0 | 0
|
| 97 | 2 | 97 2002 NEUROBIOLOGY OF AGING 23(5):957-976
Forloni G; Terreni L; Bertani I; Fogliarino S; Invernizzi R; Assini A; Ribizzi G; Negro A; Calabrese E; Volonte MA; Mariani C; Franceschi M; Tabaton M; Bertoli A
Protein misfolding in Alzheimer's and Parkinson's disease: genetics and molecular mechanisms | 0 | 0
|
| 98 | 1 | 98 2002 NEUROBIOLOGY OF DISEASE 11(1):134-146
Petersen A; Puschban Z; Lotharius J; NicNiocaill B; Wiekop P; O'Connor WT; Brundin P
Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice | 0 | 0
|
| 99 | 1 | 99 2002 NEUROCHEMISTRY INTERNATIONAL 41(6):383-389
Soti C; Csermely M
Chaperones and aging: role in neurodegeneration and in other civilizational diseases | 0 | 0
|
| 100 | 1 | 100 2002 NEUROLOGY 58(2):179-185
Mouradian MM
Recent advances in the genetics and pathogenesis of Parkinson disease | 22 | 1
|
| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 101 | 4 | 101 2002 NEURON 35(5):819-822
Ross CA
Polyglutamine pathogenesis: Emergence of unifying mechanisms for Huntington's disease and related disorders | 4 | 3
|
| 102 | 2 | 102 2002 NEURON 36(6):1007-1019
Petrucelli L; O'Farrell C; Lockhart PJ; Baptista M; Kehoe K; Vink L; Choi P; Wolozin B; Farrer M; Hardy J; Cookson MR
Parkin protects against the toxicity associated with mutant alpha-synuclein: Proteasome dysfunction selectively affects catecholaminergic neurons | 2 | 1
|
| 103 | 1 | 103 2002 NEUROSCIENCE LETTERS 323(3):215-218
Shimohata T; Sato A; Burke JR; Strittmatter WJ; Tsuji S; Onodera O
Expanded polyglutamine stretches form an 'aggresome' | 0 | 0
|
| 104 | 1 | 104 2002 NEUROSCIENCE LETTERS 333(3):163-166
D'Andrea MR; Nagele RG; Wang HY; Lee DHS
Consistent immunohistochemical detection of intracellular beta- amyloid42 in pyramidal neurons of Alzheimer's disease entorhinal cortex | 0 | 0
|
| 105 | 2 | 105 2002 NEUROTOXICOLOGY 23(4-5):503-514
Skipper L; Farrer M
Parkinson's genetics: Molecular insights for the new millennium | 1 | 0
|
| 106 | 1 | 106 2002 NEW ENGLAND JOURNAL OF MEDICINE 346(1):45-53
Carrell RW; Lomas DA
Mechanisms of disease - Alpha(1)-antitrypsin deficiency - A model for conformational diseases | 16 | 1
|
| 107 | 1 | 107 2002 ONCOGENE 21(28):4363-4373
Taylor A; Shang F; Nowell T; Galanty Y; Shiloh Y
Ubiquitination capabilities in response to neocarzinostatin and H2O2 stress in cell lines from patients with ataxia- telangiectasia | 0 | 0
|
| 108 | 2 | 108 2002 PHARMACOLOGICAL REVIEWS 54(3):469-525
Suh YH; Checler F
Amyloid precursor protein, presenilins, and alpha-synuclein: Molecular pathogenesis and pharmacological applications in Alzheimer's disease | 2 | 1
|
| 109 | 4 | 109 2002 PHYSIOLOGICAL REVIEWS 82(2):373-428
Glickman MH; Ciechanover A
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction | 22 | 0
|
| 110 | 1 | 110 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(1):333-338
Karlin S; Brocchieri L; Bergman A; Mrazek J; Gentles AJ
Amino acid runs in eukaryotic proteomes and disease associations | 1 | 0
|
| 111 | 1 | 111 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(2):727-732
Muchowski PJ; Ning K; D'Souza-Schorey C; Fields S
Requirement of an intact microtubule cytoskeleton for aggregation and inclusion body formation by a mutant huntingtin fragment | 3 | 1
|
| 112 | 3 | 112 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(14):9310-9315
Chai YH; Shao JQ; Miller VM; Williams A; Paulson HL
Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis | 2 | 0
|
| 113 | 1 | 113 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(20):13067-13072
Marmorstein LHY; Munier FL; Arsenijevic Y; Schorderet DF; McLaughlin PJ; Chung D; Traboulsi E; Marmorstein AD
Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration | 0 | 0
|
| 114 | 4 | 114 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99():16412-16418
Sakahira H; Breuer P; Hayer-Hartl MK; Hartl FU
Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity | 1 | 0
|
| 115 | 1 | 115 2002 PROTEASES IN BIOLOGY AND MEDICINE 38():51-63
Doherty FJ; Dawson S; Mayer RJ
The ubiquitin-proteasome pathway of intracellular proteolysis | 0 | 0
|
| 116 | 1 | 116 2002 PROTEASOME-UBIQUITIN PROTEIN DEGRADATION PATHWAY 268():175-184
Gordon C
The intracellular localization of the proteasome | 0 | 0
|
| 117 | 3 | 117 2002 REVISTA DE NEUROLOGIA 35(3):212-220
Martin-Aparicio E; Lucas JJ
Molecular basis of Huntington's disease and possible pathogenic mechanisms | 0 | 0
|
| 118 | 3 | 118 2002 SCIENCE 296(5575):1991-1995
Taylor JP; Hardy J; Fischbeck KH
Biomedicine - Toxic proteins in neurodegenerative disease | 12 | 4
|
| 119 | 2 | 119 2002 TRENDS IN NEUROSCIENCES 25(12):616-620
Checler F; Vincent B
Alzheimer's and prion diseases: distinct pathologies, common proteolytic denominators | 0 | 0
|
| 120 | 2 | 120 2002 VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 65 65():127-147
Walcott JL; Merry DE
Trinucleotide repeat disease - The androgen receptor in spinal and bulbar muscular atrophy | 0 | 0
|
| 121 | 2 | 121 2003 EMBO JOURNAL 22(3):404-417
Cohen E; Taraboulos A
Scrapie-like prion protein accumulates in aggresomes of cyclosporin A-treated cells | 0 | 0
|
| 122 | 1 | 122 2003 EXPERIMENTAL ANIMALS 52(1):1-9
Kwon J; Kikuchi T; Setsuie R; Ishii Y; Kyuwa S; Yoshikawa Y
Characterization of the testis in congenitally ubiquitin carboxy-terminal hydrolase-1 (Uch-L1) defective (gad) mice | 0 | 0
|
| 123 | 2 | 123 2003 EXPERT OPINION ON THERAPEUTIC PATENTS 13(1):45-57
Adams J
Proteasome inhibitors as therapeutic agents | 0 | 0
|
| 124 | 3 | 124 2003 HUMAN MOLECULAR GENETICS 12(1):1-12
Jiang HB; Nucifora FC; Ross CA; DeFranco DB
Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB- binding protein | 0 | 0
|
| 125 | 2 | 125 2003 HUMAN MOLECULAR GENETICS 12(3):307-319
Caldwell GA; Cao S; Sexton EG; Gelwix CC; Bevel JP; Caldwell KA
Suppression of polyglutamine-induced protein aggregation in Caenorhabditis elegans by torsin proteins | 0 | 0
|
| 126 | 2 | 126 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(7):4699-4704
den Engelsman J; Keijsers V; de Jong WW; Boelens WC
The small heat-shock protein alpha B-crystallin promotes FBX4- dependent ubiquitination | 0 | 0
|
| 127 | 1 | 127 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(8):6235-6242
Gautreau A; Fievet BT; Brault E; Antony C; Houdusse A; Louvard D; Arpin M
Isolation and characterization of an aggresome determinant in the NF2 tumor suppressor | 0 | 0
|
| 128 | 1 | 128 2003 JOURNAL OF NEUROBIOLOGY 54(3):417-438
Aravamudan B; Broadie K
Synaptic Drosophila UNC-13 is regulated by antagonistic G- protein pathways via a proteasome-dependent degradation mechanism | 0 | 0
|
| 129 | 1 | 129 2003 JOURNAL OF NEUROCHEMISTRY 84(1):10-22
Gu YP; Verghese S; Mishra RS; Xu XM; Shi YC; Singh N
Mutant prion protein-mediated aggregation of normal prion protein in the endoplasmic reticulum: implications for prion propagation and neurotoxicity | 0 | 0
|
| 130 | 2 | 130 2003 JOURNAL OF NEUROSCIENCE 23(4):1254-1264
Finley KD; Edeen PT; Cumming RC; Mardahl-Dumesnil MD; Taylor BJ; Rodriguez MH; Hwang CE; Benedetti M; McKeown M
blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration | 0 | 0
|
| 131 | 2 | 131 2003 JOURNAL OF PATHOLOGY 199(2):259-266
Kuazi AD; Kito K; Abe Y; Shin RW; Kamitani T; Ueda N
NEDD8 protein is involved in ubiquitinated inclusion bodies | 0 | 0
|
| 132 | 1 | 132 2003 MEDICAL HYPOTHESES 60(2):209-214
Rico A
Prion: toxic or infectious agent? | 0 | 0
|
| 133 | 2 | 133 2003 NATURE 421(6921):373-379
Sanchez I; Mahlke C; Yuan JY
Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders | 1 | 0
|
| 134 | 4 | 134 2003 NEURON 37(1):7-10
Cookson MR
Pathways to parkinsonism | 0 | 0
|
| 135 | 1 | 135 2003 NEWS IN PHYSIOLOGICAL SCIENCES 18():29-33
Klimaschewski L
Ubiquitin-dependent proteolysis in neurons | 0 | 0
|
| 136 | 3 | 136 2003 PARKINSON'S DISEASE 91():165-174
Golbe LI
alpha-synuclein and Parkinson's disease | 0 | 0
|
| 137 | 2 | 137 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(1):1-3
Ross CA; Poirier MA; Wanker EE; Amzel M
Polyglutamine fibrillogenesis: The pathway unfolds | 0 | 0
|
| 138 | 4 | 138 2003 PROTEINS-STRUCTURE FUNCTION AND GENETICS 50(2):355-370
Albrecht M; Hoffmann D; Evert BO; Schmitt I; Wullner U; Lengauer T
Structural modeling of ataxin-3 reveals distant homology to adaptins | 0 | 0
|
| 139 | 5 | 139 2003 TRENDS IN PHARMACOLOGICAL SCIENCES 24(1):18-23
Miller RJ; Wilson SM
Neurological disease: UPS stops delivering! | 0 | 0
|