| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 1 | 1 | 1 2001 ANALYTICAL BIOCHEMISTRY 295(2):227-236
Berthelier V; Hamilton JB; Chen SM; Wetzel R
A microtiter plate assay for polyglutamine aggregate extension | 3 | 2
|
| 2 | 1 | 2 2001 ANNALS OF NEUROLOGY 50(3):373-380
Margolis RL; O'Hearn E; Rosenblatt A; Willour V; Holmes SE; Franz ML; Callahan C; Hwang HS; Troncoso JC; Ross CA
A disorder similar to Huntington's disease is associated with a novel CAG repeat expansion | 12 | 2
|
| 3 | 2 | 3 2001 ANNALS OF NEUROLOGY 50(6):830-380B
Margolis RL; O'Hearn E; Rosenblatt A; Willour V; Holmes SE; Franz ML; Callahan C; Hwang HS; Troncoso JC; Ross CA
A disorder similar to Huntington's disease is associated with a novel CAG repeat expansion (vol 50, pg 373, 2001) | 0 | 0
|
| 4 | 1 | 4 2001 ARCHIVES OF NEUROLOGY 58(11):1758-1759
Tsuji S
Neurogenetics in the postgenomic era | 0 | 0
|
| 5 | 1 | 5 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 288(3):703-710
Ren H; Nagai Y; Tucker T; Strittmatter WJ; Burke JR
Amino acid sequence requirements of peptides that inhibit polyglutamine-protein aggregation and cell death | 0 | 0
|
| 6 | 1 | 6 2001 BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE 79(5):557-568
Glover JR; Tkach JM
Crowbars and ratchets: Hsp100 chaperones as tools in reversing protein aggregation | 2 | 0
|
| 7 | 1 | 7 2001 BRAIN RESEARCH 919(1):12-19
Takahashi H; Egawa S; Piao YS; Hayashi S; Yamada M; Shimohata T; Oyanagi K; Tsuji S
Neuronal nuclear alterations in dentatorubral-pallidoluysian atrophy: ultrastructural and morphometric studies of the cerebellar granule cells | 3 | 0
|
| 8 | 1 | 8 2001 BRAIN RESEARCH BULLETIN 55(4):533-540
Jain M; Armstrong RJE; Barker RA; Rosser AE
Cellular and molecular aspects of striatal development | 0 | 0
|
| 9 | 1 | 9 2001 BRAIN RESEARCH BULLETIN 56(3-4):209-214
Gallo JM
Kennedy's disease: A triplet repeat disorder or a motor neuron disease? | 1 | 0
|
| 10 | 2 | 10 2001 EMBO JOURNAL 20(22):6236-6245
Uptain SM; Sawicki GJ; Caughey B; Lindquist S
Strains of [PSI+] are distinguished by their efficiencies of prion-mediated conformational conversion | 8 | 0
|
| 11 | 1 | 11 2001 FRONTIERS IN BIOSCIENCE 6():D1024-D1047
Sartorelli V; Puri PL
The link between chromatin structure, protein acetylation and cellular differentiation | 2 | 0
|
| 12 | 1 | 12 2001 HUMAN MOLECULAR GENETICS 10(14):1441-1448
Nakamura K; Jeong SY; Uchihara T; Anno M; Nagashima K; Nagashima T; Ikeda S; Tsuji S; Kanazawa I
SCA17, a novel autosomal dominant cerebellar ataxia caused by an expanded polyglutamine in TATA-binding protein | 46 | 15
|
| 13 | 1 | 13 2001 HUMAN MOLECULAR GENETICS 10(17):1829-1845
Wyttenbach A; Swartz J; Kita H; Thykjaer T; Carmichael J; Bradley J; Brown R; Maxwell M; Schapira A; Orntoft TF; Kato K; Rubinsztein DC
Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease | 21 | 15
|
| 14 | 1 | 14 2001 HUMAN MOLECULAR GENETICS 10(21):2425-2435
Sathasivam K; Woodman B; Mahal A; Bertaux F; Wanker EE; Shima DT; Bates GP
Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients | 2 | 1
|
| 15 | 3 | 15 2001 HUMAN MOLECULAR GENETICS 10(24):2821-2831
Matilla A; Gorbea C; Einum DD; Townsend J; Michalik A; van Broeckhoven C; Jensen CC; Murphy KJ; Ptacek LJ; Fu YH
Association of ataxin-7 with the proteasome subunit S4 of the 19S regulatory complex | 2 | 0
|
| 16 | 1 | 16 2001 HUMAN MOLECULAR GENETICS 10(26):3063-3074
Welch WJ; Diamond MI
Glucocorticoid modulation of androgen receptor nuclear aggregation and cellular toxicity is associated with distinct forms of soluble expanded polyglutamine protein | 3 | 0
|
| 17 | 1 | 17 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(48):44889-44897
Chai YH; Wu LZ; Griffin JD; Paulson HL
The role of protein composition in specifying nuclear inclusion formation in polyglutamine disease | 7 | 3
|
| 18 | 1 | 18 2001 JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY 54(6):409-413
Davies S; Ramsden DB
Huntington's disease | 2 | 0
|
| 19 | 1 | 19 2001 JOURNAL OF MOLECULAR BIOLOGY 311(1):173-182
Chen S; Berthelier V; Yang W; Wetzel R
Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity | 16 | 5
|
| 20 | 1 | 20 2001 JOURNAL OF NEUROSCIENCE 21(21):8473-8481
Li H; Li SH; Yu ZX; Shebourne P; Li XJ
Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice | 9 | 2
|
| 21 | 2 | 21 2001 JOURNAL OF NEUROSCIENCE 21(22):8772-8781
Martin-Aparicio E; Yamamoto A; Hernandez F; Hen R; Avila JS; Lucas JJ
Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease | 9 | 0
|
| 22 | 1 | 22 2001 MOLECULAR NEUROBIOLOGY 23(1):21-51
Sipione S; Cattaneo E
Modeling Huntington's disease in cells, flies, and mice | 7 | 2
|
| 23 | 1 | 23 2001 NATURE 412(6843):143-144
Perutz MF; Windle AH
Cause of neural death in neurodegenerative diseases attributable to expansion of glutamine repeats | 24 | 8
|
| 24 | 3 | 24 2001 NATURE 413(6857):691-+
Bates GP
Huntington's disease - Exploiting expression | 1 | 1
|
| 25 | 1 | 25 2001 NATURE 413(6857):739-743
Steffan JS; Bodai L; Pallos J; Poelman M; McCampbell A; Apostol BL; Kazantsev A; Schmidt E; Zhu YZ; Greenwald M; Kurokawa R; Housman DE; Jackson GR; Marsh JL; Thompson LM
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila | 68 | 44
|
| 26 | 1 | 26 2001 NATURE GENETICS 29(3):270-278
Dyer RB; McMurray CT
Mutant protein in Huntington disease is resistant to proteolysis in affected brain | 16 | 9
|
| 27 | 1 | 27 2001 NATURE MEDICINE 7(5):528-530
McCampbell A; Fischbeck KH
Polyglutamine and CBP: Fatal attraction? | 13 | 8
|
| 28 | 1 | 28 2001 NEUROBIOLOGY OF DISEASE 8(6):1017-1026
Smith DL; Portier R; Woodman B; Hockly E; Mahal A; Klunk WE; Li XJ; Wanker E; Murray KD; Bates GP
Inhibition of polyglutamine aggregation in R6/2 HD brain slices - Complex dose-response profiles | 1 | 1
|
| 29 | 1 | 29 2001 NEURON 31(6):875-876
Orr HT
Qs in the nucleus | 2 | 1
|
| 30 | 1 | 30 2001 NEURON 31(6):913-927
La Spada AR; Fu YH; Sopher BL; Libby RT; Wang XJ; Li LY; Einum DD; Huang J; Possin DE; Smith AC; Martinez RA; Koszdin KL; Treuting PM; Ware CB; Hurley JB; Ptacek LJ; Chen SM
Polyglutamine-expanded ataxin-7 antagonizes CRX function and induces cone-rod dystrophy in a mouse model of SCA7 | 18 | 0
|
| 31 | 1 | 31 2001 NEUROREPORT 12(15):3371-3373
Andreassen OA; Ferrante RJ; Dedeoglu A; Beal MF
Lipoic acid improves survival in transgenic mouse models of Huntington's disease | 4 | 2
|
| 32 | 1 | 32 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(23):13060-13065
Rajan RS; Illing ME; Bence NF; Kopito RR
Specificity in intracellular protein aggregation and inclusion body formation | 11 | 3
|
| 33 | 1 | 33 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(23):13201-13206
Hughes RE; Lo RS; Davis C; Strand AD; Neal CL; Olson JM; Fields S
Altered transcription in yeast expressing expanded polyglutamine | 14 | 11
|
| 34 | 1 | 34 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(23):13318-13323
Parker JA; Connolly JB; Wellington C; Hayden M; Dausset J; Neri C
Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death | 7 | 3
|
| 35 | 4 | 35 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(26):15179-15184
McCampbell A; Taye AA; Whitty L; Penney E; Steffan JS; Fischbeck KH
Histone deacetylase inhibitors reduce polyglutamine toxicity | 16 | 15
|
| 36 | 0 | 36 2001 SCIENCE 291(5512):2423-2428
Nucifora FC; Sasaki M; Peters MF; Huang H; Cooper JK; Yamada M; Takahashi H; Tsuji S; Troncoso J; Dawson VL; Dawson TM; Ross CA
Interference by Huntingtin and atrophin-1 with CBP-mediated transcription leading to cellular toxicity | 132 | 132
|
| 37 | 1 | 37 2001 SCIENTIST 15(8):14-14
Lewis R
Understanding Huntington's disease | 0 | 0
|
| 38 | 1 | 38 2001 SELECTIVE ESTROGEN RECEPTOR MODULATORS (SERMS) 949():44-57
Roy AK; Tyagi RK; Song CS; Lavrovsky Y; Ahn SC; Oh TS; Chatterjee B
Androgen receptor: Structural domains and functional dynamics after ligand-receptor interaction | 2 | 0
|
| 39 | 1 | 39 2001 TRENDS IN MOLECULAR MEDICINE 7(7):283-284
Neri C
New light on polyglutamine neurodegenerative disorders: interference with transcription | 1 | 1
|
| 40 | 3 | 40 2001 TRENDS IN MOLECULAR MEDICINE 7(11):479-482
Margolis RL; Ross CA
Expansion explosion: new clues to the pathogenesis of repeat expansion neurodegenerative diseases | 7 | 2
|
| 41 | 1 | 41 2001 TRENDS IN NEUROSCIENCES 24(11):S32-S38
McMurray CT
Huntington's disease: new hope for therapeutics | 4 | 1
|
| 42 | 2 | 42 2002 ADVANCES IN CANCER RESEARCH, VOL 86 86():41-65
Lehrmann H; Pritchard LL; Harel-Bellan A
Histone acetyltransferases and deacetylases in the control of cell proliferation and differentiation | 0 | 0
|
| 43 | 1 | 43 2002 AMERICAN JOURNAL OF PATHOLOGY 161(6):2087-2098
Zhu JH; Kulich SM; Oury TD; Chu CT
Cytoplasmic aggregates of phosphorylated extracellular signal- regulated protein kinases in Lewy body diseases | 1 | 0
|
| 44 | 1 | 44 2002 ANNALS OF NEUROLOGY 52(5):670-674
Yamada M; Sato T; Tsuji S; Takahashi H
Oligodendrocytic polyglutamine pathology in dentatorubral- pallidoluysian atrophy | 0 | 0
|
| 45 | 2 | 45 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 293(1):307-313
Ueda H; Goto J; Hashida H; Lin X; Oyanagi K; Kawano H; Zoghbi HY; Kanazawa I; Okazawa H
Enhanced SUMOylation in polyglutamine diseases | 1 | 0
|
| 46 | 2 | 46 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 294(2):268-271
Enokido Y; Maruoka H; Hatanaka H; Kanazawa I; Okazawa H
PQBP-1 increases vulnerability to low potassium stress and represses transcription in primary cerebellar neurons | 0 | 0
|
| 47 | 4 | 47 2002 BIOCHEMISTRY 41(23):7391-7399
Chen SM; Berthelier V; Hamilton JB; O'Nuallain B; Wetzel R
Amyloid-like features of polyglutamine aggregates and their assembly kinetics | 6 | 1
|
| 48 | 3 | 48 2002 BIOCHIMIE 84(4):273-278
Hoffner G; Djian P
Protein aggregation in Huntington's disease | 0 | 0
|
| 49 | 1 | 49 2002 BRAIN 125():1534-1543
Takahashi J; Fujigasaki H; Zander C; El Hachimi KH; Stevanin G; Durr A; Lebre AS; Yvert G; Trottier Y; de The H; Hauw JJ; Duyckaerts C; Brice A
Two populations of neuronal intranuclear inclusions in SCA7 differ in size and promyelocytic leukaemia protein content | 1 | 0
|
| 50 | 1 | 50 2002 BRAIN RESEARCH 939(1-2):76-86
Deckel AW; Tang V; Nuttal D; Gary K; Elder R
Altered neuronal nitric oxide synthase expression contributes to disease progression in Huntington's disease transgenic mice | 0 | 0
|
| 51 | 1 | 51 2002 BRAIN RESEARCH 956(2):312-318
Chung YH; Kim EJ; Shin CM; Joo KM; Kim MJ; Woo HW; Cha CI
Age-related changes in CREB binding protein immunoreactivity in the cerebral cortex and hippocampus of rats | 0 | 0
|
| 52 | 1 | 52 2002 CELL DEATH AND DIFFERENTIATION 9(3):264-273
Higashiyama H; Hirose F; Yamaguchi M; Inoue YH; Fujikake N; Matsukage A; Kakizuka A
Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced neurodegeneration | 6 | 2
|
| 53 | 5 | 53 2002 CURRENT BIOLOGY 12(4):R141-R143
Hughes RE
Polyglutamine disease: Acetyltransferases awry | 1 | 0
|
| 54 | 5 | 54 2002 CURRENT OPINION IN NEUROLOGY 15(4):483-489
Feigin A; Zgaljardic D
Recent advances in Huntington's disease: implications for experimental therapeutics | 0 | 0
|
| 55 | 3 | 55 2002 EUROPEAN JOURNAL OF NEUROSCIENCE 16(2):355-359
Martin-Aparicio E; Avila J; Lucas JJ
Nuclear localization of N-terminal mutant huntingtin is cell cycle dependent | 0 | 0
|
| 56 | 3 | 56 2002 EXPERT OPINION ON INVESTIGATIONAL DRUGS 11(10):1407-1435
Moosmann B; Behl C
Antioxidants as treatment for neurodegenerative disorders | 0 | 0
|
| 57 | 1 | 57 2002 FEBS LETTERS 515(1-3):61-65
Chun W; Lesort M; Lee M; Johnson GVW
Mutant huntingtin aggregates do not sensitize cells to apoptotic stressors | 0 | 0
|
| 58 | 2 | 58 2002 GENES & DEVELOPMENT 16(11):1345-1355
Nishitoh H; Matsuzawa A; Tobiume K; Saegusa K; Takeda K; Inoue K; Hori S; Kakizuka A; Ichijo H
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats | 14 | 0
|
| 59 | 2 | 59 2002 HISTOLOGY AND HISTOPATHOLOGY 17(2):657-668
Janknecht R
The versatile functions of the transcriptional coactivators p300 and CBP and their roles in disease | 4 | 0
|
| 60 | 4 | 60 2002 HUMAN MOLECULAR GENETICS 11(8):905-914
Yu ZX; Li SH; Nguyen HP; Li XJ
Huntingtin inclusions do not deplete polyglutamine-containing transcription factors in HD mice | 4 | 3
|
| 61 | 11 | 61 2002 HUMAN MOLECULAR GENETICS 11(17):1911-1926
Luthi-Carter R; Hanson SA; Strand AD; Bergstrom DA; Chun WJ; Peters NL; Woods AM; Chan EY; Kooperberg C; Krainc D; Young AB; Tapscott SJ; Olson JM
Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain | 5 | 0
|
| 62 | 7 | 62 2002 HUMAN MOLECULAR GENETICS 11(17):1927-1937
Luthi-Carter R; Strand AD; Hanson SA; Kooperberg C; Schilling G; La Spada AR; Merry DE; Young AB; Ross CA; Borchelt DR; Olson JM
Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context- independent effects | 3 | 0
|
| 63 | 9 | 63 2002 HUMAN MOLECULAR GENETICS 11(17):1939-1951
Chan EYW; Luthi-Carter R; Strand A; Solano SM; Hanson SA; DeJohn MM; Kooperberg C; Chase KO; DiFiglia M; Young AB; Leavitt BR; Cha JHJ; Aronin N; Hayden MR; Olson JM
Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease | 3 | 2
|
| 64 | 5 | 64 2002 HUMAN MOLECULAR GENETICS 11(17):1953-1965
Sipione S; Rigamonti D; Valenza M; Zuccato C; Conti L; Pritchard J; Kooperberg C; Olson JM; Cattaneo E
Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses | 4 | 2
|
| 65 | 5 | 65 2002 HUMAN MOLECULAR GENETICS 11(17):1967-1976
Lieberman AP; Harmison G; Strand AD; Olson JM; Fischbeck KH
Altered transcriptional regulation in cells expressing the expanded polyglutamine androgen receptor | 1 | 1
|
| 66 | 5 | 66 2002 HUMAN MOLECULAR GENETICS 11(19):2233-2241
Fossale E; Wheeler VC; Vrbanac V; Lebel LA; Teed A; Mysore JS; Gusella JF; MacDonald ME; Persichetti F
Identification of a presymptomatic molecular phenotype in Hdh CAG knock-in mice | 0 | 0
|
| 67 | 4 | 67 2002 HUMAN MOLECULAR GENETICS 11(19):2279-2287
Kita H; Carmichael J; Swartz J; Muro S; Wyttenbach A; Matsubara K; Rubinsztein DC; Kato K
Modulation of polyglutamine-induced cell death by genes identified by expression profiling | 0 | 0
|
| 68 | 5 | 68 2002 HUMAN MOLECULAR GENETICS 11(21):2657-2672
Kazemi-Esfarjani P; Benzer S
Suppression of polyglutamine toxicity by a Drosophila homolog of myeloid leukemia factor 1 | 0 | 0
|
| 69 | 6 | 69 2002 HUMAN MOLECULAR GENETICS 11(22):2689-2700
Verhoef LGGC; Lindsten K; Masucci MG; Dantuma NP
Aggregate formation inhibits proteasomal degradation of polyglutamine proteins | 0 | 0
|
| 70 | 5 | 70 2002 HUMAN MOLECULAR GENETICS 11(23):2815-2828
Singaraja RR; Hadano S; Metzler M; Givan S; Wellington CL; Warby S; Yanai A; Gutekunst CA; Leavitt BR; Yi H; Fichter K; Gan L; McCutcheon K; Chopra V; Michel J; Hersch SM; Ikeda JE; Hayden MR
HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis | 0 | 0
|
| 71 | 7 | 71 2002 HUMAN MOLECULAR GENETICS 11(23):2905-2917
Yang W; Dunlap JR; Andrews RB; Wetzel R
Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells | 3 | 1
|
| 72 | 3 | 72 2002 HUMAN MOLECULAR GENETICS 11(26):3351-3359
Helmlinger D; Yvert G; Picaud S; Merienne K; Sahel J; Mandel JL; Devys D
Progressive retinal degeneration and dysfunction in R6 Huntington's disease mice | 0 | 0
|
| 73 | 1 | 73 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(9):7466-7476
Kegel KB; Meloni AR; Yi Y; Kim YJ; Doyle E; Cuiffo BG; Sapp E; Wang YM; Qin ZH; Chen JD; Nevins JR; Aronin N; DiFiglia M
Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription | 8 | 6
|
| 74 | 1 | 74 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(18):16116-16123
Golts N; Snyder H; Frasier M; Theisler C; Choi P; Wolozin B
Magnesium inhibits spontaneous and iron-induced aggregation of alpha-synuclein | 0 | 0
|
| 75 | 5 | 75 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(40):37536-37541
Kimura Y; Koitabashi S; Kakizuka A; Fujita T
Circumvention of chaperone requirement for aggregate formation of a short polyglutamine tract by the co-expression of a long polyglutamine tract | 0 | 0
|
| 76 | 7 | 76 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(47):45004-45012
Li FS; Macfarlan T; Pittman RN; Chakravarti D
Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities | 0 | 0
|
| 77 | 1 | 77 2002 JOURNAL OF NEUROCHEMISTRY 82(6):1416-1423
Yohrling GJ; Jiang GCT; DeJohn MM; Robertson DJ; Vrana KE; Cha JHJ
Inhibition of tryptophan hydroxylase activity and decreased 5- HT1A receptor binding in a mouse model of Huntington's disease | 0 | 0
|
| 78 | 1 | 78 2002 JOURNAL OF NEUROSCIENCE 22(6):2174-2184
Garcia M; Vanhoutte P; Pages C; Besson MJ; Brouillet E; Caboche J
The mitochondrial toxin 3-nitropropionic acid induces striatal neurodegeneration via a c-Jun N-terminal kinase/c-Jun module | 1 | 0
|
| 79 | 2 | 79 2002 JOURNAL OF NEUROSCIENCE 22(18):7862-7872
Wellington CL; Ellerby LM; Gutekunst CA; Rogers D; Warby S; Graham RK; Loubser O; van Raamsdonk J; Singaraja R; Yang YZ; Gafni J; Bredesen D; Hersch SM; Leavitt BR; Roy S; Nicholson DW; Hayden MR
Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease | 1 | 0
|
| 80 | 2 | 80 2002 JOURNAL OF NEUROSCIENCE 22(21):9267-9277
Mitsui K; Nakayama H; Akagi T; Nekooki M; Ohtawa K; Takio K; Hashikawa T; Nukina N
Purification of polyglutamine aggregates and identification of elongation factor-1 alpha and heat shock protein 84 as aggregate-interacting proteins | 0 | 0
|
| 81 | 2 | 81 2002 JOURNAL OF NEUROSCIENCE RESEARCH 68(4):442-448
Toyoshima I; Sugawara M; Kato K; Wada C; Shimohata T; Koide R; Onodera O; Tsuji S
Time course of polyglutamine aggregate body formation and cell death: Enhanced growth in nucleus and an interval for cell death | 0 | 0
|
| 82 | 5 | 82 2002 MITOCHONDRIAL FUNCTION AND DYSFUNCTION 53():315-339
Petersen A; Brundin P
Huntington's disease: The mystery unfolds? | 0 | 0
|
| 83 | 1 | 83 2002 MOLECULAR AND CELLULAR BIOLOGY 22(5):1277-1287
Li SH; Cheng AL; Zhou H; Lam S; Rao M; Li H; Li XJ
Interaction of Huntington disease protein with transcriptional activator Sp1 | 11 | 10
|
| 84 | 2 | 84 2002 MOLECULAR BRAIN RESEARCH 102(1-2):118-128
Spektor BS; Miller DW; Hollingsworth ZR; Kaneko YA; Solano SM; Johnson JM; Penney JB; Young AB; Luthi-Carter R
Differential D-1 and D-2 receptor-mediated effects on immediate early gene induction in a transgenic mouse model of Huntington's disease | 0 | 0
|
| 85 | 3 | 85 2002 MOLECULAR BRAIN RESEARCH 109(1-2):1-10
van Roon-Mom WMC; Reid SJ; Jones AL; MacDonald ME; Faull RLM; Snell RG
Insoluble TATA-binding protein accumulation in Huntington's disease cortex | 0 | 0
|
| 86 | 1 | 86 2002 MYOCLONUS AND PAROXYSMAL DYSKINESIAS 89():231-239
Tsuji S
Dentatorubral-pallidoluysian atrophy: Clinical aspects and molecular genetics | 0 | 0
|
| 87 | 1 | 87 2002 NATURE 415(6871):549-553
Demarest SJ; Martinez-Yamout M; Chung J; Chen HW; Xu W; Dyson HJ; Evans RM; Wright PE
Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators | 16 | 0
|
| 88 | 1 | 88 2002 NATURE CELL BIOLOGY 4(2):95-105
Gervais FG; Singaraja R; Xanthoudakis S; Gutekunst CA; Leavitt BR; Metzler M; Hackam AS; Tam J; Vaillancourt JP; Houtzager V; Rasper DM; Roy S; Hayden MR; Nicholson DW
Recruitment and activation of caspase-8 by the Huntingtin- interacting protein Hip-1 and a novel partners Hippi | 15 | 4
|
| 89 | 2 | 89 2002 NATURE CELL BIOLOGY 4(10):806-810
Stenoien DL; Mielke M; Mancini MA
Intranuclear ataxin1 inclusions contain both fast- and slow- exchanging components | 0 | 0
|
| 90 | 2 | 90 2002 NATURE CELL BIOLOGY 4(10):826-831
Kim S; Nollen EAA; Kitagawa K; Bindokas VP; Morimoto RI
Polyglutamine protein aggregates are dynamic | 1 | 0
|
| 91 | 2 | 91 2002 NATURE GENETICS 31(1):47-54
Mantamadiotis T; Lemberger T; Bleckmann SC; Kern H; Kretz O; Villalba AM; Tronche F; Kellendonk C; Gau D; Kapfhammer J; Otto C; Schmid W; Schutz G
Disruption of CREB function in brain leads to neurodegeneration | 11 | 4
|
| 92 | 4 | 92 2002 NATURE MEDICINE 8(5):450-451
Dawson TM; Ginty DD
CREB family transcription factors inhibit neuronal suicide | 2 | 1
|
| 93 | 2 | 93 2002 NATURE NEUROSCIENCE 5(8):731-736
Panov AV; Gutekunst CA; Leavitt BR; Hayden MR; Burke JR; Strittmatter WJ; Greenamyre JT
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines | 5 | 2
|
| 94 | 3 | 94 2002 NEUROBIOLOGY OF DISEASE 10(3):410-426
Blum D; Galas MC; Gall D; Cuvelier L; Schiffmann SN
Striatal and cortical neurochemical changes induced by chronic metabolic compromise in the 3-nitropropionic model of Huntington's disease | 1 | 0
|
| 95 | 1 | 95 2002 NEUROBIOLOGY OF DISEASE 11(1):111-122
Sun B; Fan W; Balciunas A; Cooper JK; Bitan G; Steavenson S; Denis PE; Young Y; Adler B; Daugherty L; Manoukian R; Elliott G; Shen WY; Talvenheimo J; Teplow DB; Haniu M; Haldankar R; Wypych J; Ross CA; Citron M; Richards WG
Polyglutamine repeat length-dependent proteolysis of huntingtin | 0 | 0
|
| 96 | 6 | 96 2002 NEUROBIOLOGY OF DISEASE 11(3):410-424
Andreassen OA; Dedeoglu A; Stanojevic V; Hughes DB; Browne SE; Leech CA; Ferrante RJ; Habener JF; Beal MF; Thomas MK
Huntington's disease of the endocrine pancreas: Insulin deficiency and diabetes mellitus due to impaired insulin gene expression | 0 | 0
|
| 97 | 1 | 97 2002 NEUROLOGY 58(5):687-695
Hauser RA; Furtado S; Cimino CR; Delgado H; Eichler S; Schwartz S; Scott D; Nauert GM; Soety E; Sossi V; Holt DA; Sanberg PR; Stoessl AJ; Freeman TB
Bilateral human fetal striatal transplantation in Huntington's disease | 7 | 0
|
| 98 | 1 | 98 2002 NEURON 34(3):371-385
Lonze BE; Riccio A; Cohen S; Ginty DD
Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB | 12 | 1
|
| 99 | 2 | 99 2002 NEURON 34(5):701-713
Okazawa H; Rich T; Chang A; Lin X; Waragai M; Kajikawa M; Enokido Y; Komuro A; Kato S; Shibata M; Hatanaka H; Mouradian MM; Sudol M; Kanazawa I
Interaction between mutant ataxin-1 and POBP-1 affects transcription and cell death | 3 | 2
|
| 100 | 3 | 100 2002 NEURON 34(6):905-919
Watase K; Weeber EJ; Xu BS; Antalffy B; Yuva-Paylor L; Hashimoto K; Kano M; Atkinson R; Sun YL; Armstrong DL; Sweatt JD; Orr HT; Paylor R; Zoghbi HY
A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration | 11 | 3
|
| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 101 | 7 | 101 2002 NEURON 35(4):605-623
Lonze BE; Ginty DD
Function and regulation of CREB family transcription factors in the nervous system | 8 | 0
|
| 102 | 9 | 102 2002 NEURON 35(5):819-822
Ross CA
Polyglutamine pathogenesis: Emergence of unifying mechanisms for Huntington's disease and related disorders | 4 | 2
|
| 103 | 3 | 103 2002 NEURON 35(5):843-854
Katsuno M; Adachi H; Kume A; Li M; Nakagomi Y; Niwa H; Sang C; Kobayashi Y; Doyu M; Sobue G
Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy | 2 | 1
|
| 104 | 3 | 104 2002 NEUROPATHOLOGY 22(4):317-322
Yamada M; Tsuji S; Takahashi H
Genotype-phenotype correlation in CAG-repeat diseases | 0 | 0
|
| 105 | 1 | 105 2002 NEUROREPORT 13(17):2359-2364
Terashima T; Kawai H; Fujitani M; Maeda K; Yasuda H
SUMO-1 co-localized with mutant atrophin-1 with expanded polyglutamines accelerates intranuclear aggregation and cell death | 0 | 0
|
| 106 | 2 | 106 2002 NEUROREPORT 13(18):2543-2546
Chun WJ; Lesort M; Lee M; Johnson GVW
Transient osmotic stress facilitates mutant huntingtin aggregation | 0 | 0
|
| 107 | 1 | 107 2002 NEUROSCIENCE LETTERS 323(3):215-218
Shimohata T; Sato A; Burke JR; Strittmatter WJ; Tsuji S; Onodera O
Expanded polyglutamine stretches form an 'aggresome' | 0 | 0
|
| 108 | 1 | 108 2002 NEUROSCIENTIST 8(1):22-32
Wolozin B; Golts N
Iron and Parkinson's disease | 0 | 0
|
| 109 | 1 | 109 2002 NUCLEIC ACIDS RESEARCH 30(16):art. no.-e80
Wiesner C; Hoeth M; Binder BR; de Martin R
A functional screening assay for the isolation of transcription factors | 0 | 0
|
| 110 | 1 | 110 2002 PLASTICITY IN THE ADULT BRAIN: FROM GENES TO NEUROTHERAPY 138():451-464
Chmielnicki E; Goldman SA
Induced neurogenesis by endogenous progenitor cells in the adult mammalian brain | 0 | 0
|
| 111 | 1 | 111 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(2):1002-1007
Khoshnan A; Ko J; Patterson PH
Effects of intracellular expression of anti-huntingtin antibodies of various specificities on mutant huntingtin aggregation and toxicity | 4 | 3
|
| 112 | 5 | 112 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(14):9310-9315
Chai YH; Shao JQ; Miller VM; Williams A; Paulson HL
Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis | 2 | 1
|
| 113 | 3 | 113 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(16):10417-10422
Morley JF; Brignull HR; Weyers JJ; Morimoto RI
The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans | 2 | 1
|
| 114 | 3 | 114 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(16):10671-10676
Keene CD; Rodrigues CMP; Eich T; Chhabra MS; Steer CJ; Low WC
Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic model of Huntington's disease | 1 | 0
|
| 115 | 5 | 115 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99():16412-16418
Sakahira H; Breuer P; Hayer-Hartl MK; Hartl FU
Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity | 1 | 0
|
| 116 | 4 | 116 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(26):17131-17136
Faber PW; Voisine C; King DC; Bates EA; Hart AC
Glutamine/proline-rich PQE-1 proteins protect Caenorhabditis elegans neurons from huntingtin polyglutamine neurotoxicity | 1 | 0
|
| 117 | 4 | 117 2002 REVISTA DE NEUROLOGIA 35(3):212-220
Martin-Aparicio E; Lucas JJ
Molecular basis of Huntington's disease and possible pathogenic mechanisms | 0 | 0
|
| 118 | 5 | 118 2002 SCIENCE 296(5575):1991-1995
Taylor JP; Hardy J; Fischbeck KH
Biomedicine - Toxic proteins in neurodegenerative disease | 12 | 1
|
| 119 | 4 | 119 2002 SCIENCE 296(5576):2149-2150
Freiman RN; Tjian R
Perspectives: Neurodegeneration - A glutamine-rich trail leads to transcription factors | 1 | 1
|
| 120 | 4 | 120 2002 SCIENCE 296(5576):2238-2243
Dunah AW; Jeong H; Griffin A; Kim YM; Standaert DG; Hersch SM; Mouradian MM; Young AB; Tanese N; Krainc D
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease | 13 | 10
|
| 121 | 2 | 121 2002 TRAFFIC 3(6):388-396
Garcia-Mata R; Gao YS; Sztul E
Hassles with taking out the garbage: Aggravating aggresomes | 3 | 0
|
| 122 | 7 | 122 2002 TRENDS IN GENETICS 18(4):202-209
Rubinsztein DC
Lessons from animal models of Huntington's disease | 6 | 5
|
| 123 | 4 | 123 2002 TRENDS IN GENETICS 18(9):463-471
Zoghbi HY; Botas J
Mouse and fly models of neurodegeneration | 1 | 0
|
| 124 | 4 | 124 2002 TRENDS IN MOLECULAR MEDICINE 8(3):99-101
Chan HYE
Fly-ing from genes to drugs | 0 | 0
|
| 125 | 4 | 125 2002 TRENDS IN MOLECULAR MEDICINE 8(5):195-197
Taylor JP; Fischbeck KH
Altered acetylation in polyglutamine disease: an opportunity for therapeutic intervention? | 0 | 0
|
| 126 | 1 | 126 2002 TRENDS IN PHARMACOLOGICAL SCIENCES 23(1):32-39
Menalled LB; Chesselet MF
Mouse models of Huntington's disease | 6 | 3
|
| 127 | 5 | 127 2002 VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 65 65():127-147
Walcott JL; Merry DE
Trinucleotide repeat disease - The androgen receptor in spinal and bulbar muscular atrophy | 0 | 0
|
| 128 | 9 | 128 2003 HUMAN MOLECULAR GENETICS 12(1):1-12
Jiang HB; Nucifora FC; Ross CA; DeFranco DB
Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB- binding protein | 0 | 0
|
| 129 | 1 | 129 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(6):3825-3830
Lesort M; Lee M; Tucholski J; Johnson GVW
Cystamine inhibits caspase activity - Implications for the treatment of polyglutamine disorders | 0 | 0
|
| 130 | 7 | 130 2003 NEWS IN PHYSIOLOGICAL SCIENCES 18():34-37
Cattaneo E
Dysfunction of wild-type Huntingtin in Huntington disease | 0 | 0
|
| 131 | 2 | 131 2003 PEDIATRIC RESEARCH 53(3):369-374
Johnston MV; Alemi L; Harum KH
Learning, memory, and transcription factors | 0 | 0
|
| 132 | 8 | 132 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(1):1-3
Ross CA; Poirier MA; Wanker EE; Amzel M
Polyglutamine fibrillogenesis: The pathway unfolds | 0 | 0
|
| 133 | 8 | 133 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(4):2041-2046
Hockly E; Richon VM; Woodman B; Smith DL; Zhou XB; Rosa E; Sathasivam K; Ghazi-Noori S; Mahal A; Lowden PAS; Steffan JS; Marsh JL; Thompson LM; Lewis CM; Marks PA; Bates GP
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease | 0 | 0
|