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Nodes: 1364,
Authors: 3358,
Journals: 307,
Outer References: 11901,
Words: 2507
Collection span: 1995 - 2005
View: Overview. Sorted by GCS.
Page 1: 1 2 3 4 5
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 1 | 1 | 12 | 178 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(1):196-197 Turner G; Webb T; Wake S; Robinson; H Prevalence of fragile X syndrome | 153 | 235 |
| 2 | 1 | 29 | 422 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(10):5401-5404 Comery TA; Harris JB; Willems PJ; Oostra BA; Irwin SA; et al. Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits | 125 | 220 |
| 3 | 6 | 58 | 421 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(10):5395-5400 Weiler IJ; Irwin SA; Klintsova AY; Spencer CM; Brazelton AD; et al. Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation | 102 | 192 |
| 4 | 2 | 43 | 233 1996 CELL 85(2):237-245 Musco G; Stier G; Joseph C; Morelli MAC; Nilges M; et al. Three-dimensional structure and stability of the KH domain: Molecular insights into the fragile X syndrome | 22 | 178 |
| 5 | 18 | 47 | 851 2001 CELL 107(4):477-487 Brown V; Jin P; Ceman S; Darnell JC; O'Donnell WT; et al. Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome | 80 | 162 |
| 6 | 0 | 18 | 154 1995 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 92(11):5199-5203 CHEN XA; MARIAPPAN SVS; CATASTI P; RATLIFF R; MOYZIS RK; et al. HAIRPINS ARE FORMED BY THE SINGLE DNA STRANDS OF THE FRAGILE-X TRIPLET REPEATS - STRUCTURE AND BIOLOGICAL IMPLICATIONS | 33 | 161 |
| 7 | 11 | 85 | 852 2001 CELL 107(4):489-499 Darnell JC; Jensen KB; Jin P; Brown V; Warren ST; et al. Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function | 74 | 149 |
| 8 | 8 | 59 | 406 1997 JOURNAL OF NEUROSCIENCE 17(5):1539-1547 Feng Y; Gutekunst CA; Eberhart DE; Yi H; Warren ST; et al. Fragile X mental retardation protein: Nucleocytoplasmic shuttling and association with somatodendritic ribosomes | 85 | 145 |
| 9 | 0 | 29 | 489 1998 JOURNAL OF EXPERIMENTAL MEDICINE 188(12):2335-2342 Sun SQ; Zhang XH; Tough DF; Sprent J Type I interferon-mediated stimulation of T cells by CgG DNA | 0 | 135 |
| 10 | 13 | 47 | 410 1997 MOLECULAR CELL 1(1):109-118 Feng Y; Absher D; Eberhart DE; Brown V; Malter HE; et al. FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association | 89 | 134 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 11 | 5 | 53 | 260 1996 HUMAN MOLECULAR GENETICS 5(8):1083-1091 Eberhart DE; Malter HE; Feng Y; Warren ST The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals | 93 | 132 |
| 12 | 1 | 36 | 101 1995 EMBO JOURNAL 14(21):5358-5366 ZHANG Y; OCONNOR JP; SIOMI MC; SRINIVASAN S; DUTRA A; et al. THE FRAGILE-X MENTAL-RETARDATION SYNDROME PROTEIN INTERACTS WITH NOVEL HOMOLOGS FXR1 AND FXR2 | 77 | 121 |
| 13 | 0 | 42 | 39 1995 AMERICAN JOURNAL OF HUMAN GENETICS 57(5):1006-1018 ROUSSEAU F; ROUILLARD P; MOREL ML; KHANDJIAN EW; MORGAN K PREVALENCE OF CARRIERS OF PREMUTATION-SIZE ALLELES OF THE FMRI GENE AND IMPLICATIONS FOR THE POPULATION-GENETICS OF THE FRAGILE-X SYNDROME | 86 | 114 |
| 14 | 3 | 57 | 280 1996 MOLECULAR AND CELLULAR BIOLOGY 16(7):3825-3832 Siomi MC; Zhang Y; Siomi H; Dreyfuss G Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them | 58 | 109 |
| 15 | 8 | 43 | 998 2002 GENES & DEVELOPMENT 16(19):2491-2496 Caudy AA; Myers M; Hannon GJ; Hammond SM Fragile X-related protein and VIG associate with the RNA interference machinery | 26 | 109 |
| 16 | 16 | 31 | 873 2001 HUMAN MOLECULAR GENETICS 10(4):329-338 Laggerbauer B; Ostareck D; Keidel EM; Ostareck-Lederer A; Fischer U Evidence that fragile X mental retardation protein is a negative regulator of translation | 84 | 106 |
| 17 | 6 | 41 | 624 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(18):12797-12802 Fry M; Loeb LA Human Werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)(n) | 11 | 104 |
| 18 | 0 | 43 | 100 1995 EMBO JOURNAL 14(11):2401-2408 SIOMI MC; SIOMI H; SAUER WH; SRINIVASAN S; NUSSBAUM RL; et al. FXR1, AN AUTOSOMAL HOMOLOG OF THE FRAGILE-X MENTAL-RETARDATION GENE | 62 | 102 |
| 19 | 2 | 30 | 646 1999 NATURE GENETICS 22(1):98-101 Coffee B; Zhang FP; Warren ST; Reines D Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells | 27 | 102 |
| 20 | 0 | 9 | 138 1995 LANCET 345(8958):1147-1148 WILLEMSEN R; MOHKAMSING S; DEVRIES B; DEVYS D; VANDENOUWELAND A; et al. RAPID ANTIBODY-TEST FOR FRAGILE-X SYNDROME | 81 | 101 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 21 | 1 | 31 | 281 1996 NATURE GENETICS 12(1):91-93 Khandjian EW; Corbin F; Woerly S; Rousseau F The fragile X mental retardation protein is associated with ribosomes | 70 | 101 |
| 22 | 0 | 25 | 148 1995 NUCLEIC ACIDS RESEARCH 23(20):4202-4209 USDIN K; WOODFORD KJ CGG REPEATS ASSOCIATED WITH DNA INSTABILITY AND CHROMOSOME FRAGILITY FORM STRUCTURES THAT BLOCK DNA-SYNTHESIS IN-VITRO | 22 | 100 |
| 23 | 2 | 67 | 137 1995 JOURNAL OF MOLECULAR BIOLOGY 254(4):638-656 KETTANI A; KUMAR RA; PATEL DJ SOLUTION STRUCTURE OF A DNA QUADRUPLEX CONTAINING THE FRAGILE-X SYNDROME TRIPLET REPEAT | 15 | 98 |
| 24 | 14 | 37 | 854 2001 CELL 107(5):591-603 Zhang YQ; Bailey AM; Matthies HJG; Renden RB; Smith MA; et al. Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function | 57 | 98 |
| 25 | 4 | 59 | 711 2000 CELL 100(3):323-332 Lewis HA; Musunuru K; Jensen KB; Edo C; Chen H; et al. Sequence-specific RNA binding by a Nova KH domain: Implications for paraneoplastic disease and the fragile X syndrome | 9 | 97 |
| 26 | 17 | 62 | 864 2001 EMBO JOURNAL 20(17):4803-4813 Schaeffer C; Bardoni B; Mandel JL; Ehresmann B; Ehresmann C; et al. The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif | 66 | 97 |
| 27 | 0 | 44 | 120 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(45):27014-27021 KANG SM; OHSHIMA K; SHIMIZU M; AMIRHAERI S; WELLS RD PAUSING OF DNA-SYNTHESIS IN-VITRO AT SPECIFIC LOCI IN CTG AND CGG TRIPLET REPEATS FROM HUMAN HEREDITARY-DISEASE GENES | 16 | 96 |
| 28 | 7 | 40 | 652 2000 AMERICAN JOURNAL OF HUMAN GENETICS 66(1):6-15 Tassone F; Hagerman RJ; Taylor AK; Gane LW; Godfrey TE; et al. Elevated levels of FMR1 mRNA in carrier males: A new mechanism of involvement in the fragile-X syndrome | 62 | 96 |
| 29 | 9 | 38 | 384 1997 HUMAN MOLECULAR GENETICS 6(9):1465-1472 Corbin F; Bouillon M; Fortin A; Morin S; Rousseau F; et al. The fragile X mental retardation protein is associated with poly(A)(+) mRNA in actively translating polyribosomes | 70 | 93 |
| 30 | 15 | 36 | 907 2001 NUCLEIC ACIDS RESEARCH 29(11):2276-2283 Li ZZ; Zhang YY; Ku L; Wilkinson KD; Warren ST; et al. The fragile X mental retardation protein inhibits translation via interacting with mRNA | 72 | 93 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 31 | 2 | 81 | 228 1996 BIOCHEMISTRY 35(15):5041-5053 Pearson CE; Sinden RR Alternative structures in duplex DNA formed within the trinucleotide repeats of the myotonic dystrophy and fragile X loci | 4 | 91 |
| 32 | 13 | 79 | 999 2002 GENES & DEVELOPMENT 16(19):2497-2508 Ishizuka A; Siomi MC; Siomi H A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins | 27 | 91 |
| 33 | 4 | 42 | 412 1997 NATURE GENETICS 15(2):165-169 Malter HE; Iber JC; Willemsen R; deGraaff E; Tarleton JC; et al. Characterization of the full fragile X syndrome mutation in fetal gametes | 58 | 89 |
| 34 | 0 | 51 | 4 1995 AMERICAN JOURNAL OF HUMAN GENETICS 57(2):351-361 ZHONG N; YANG WH; DOBKIN C; BROWN WT FRAGILE-X GENE INSTABILITY - ANCHORING AGGS AND LINKED MICROSATELLITES | 54 | 82 |
| 35 | 32 | 82 | 737 2000 HUMAN MOLECULAR GENETICS 9(6):901-908 Jin P; Warren ST Understanding the molecular basis of fragile X syndrome | 44 | 82 |
| 36 | 6 | 35 | 305 1997 AMERICAN JOURNAL OF HUMAN GENETICS 61(3):660-667 deVries BBA; vandenOuweland AMW; Mohkamsing S; Duivenvoorden HJ; Mol E; et al. Screening and diagnosis for the fragile X syndrome among the mentally retarded: An epidemiological and psychological survey | 44 | 80 |
| 37 | 11 | 46 | 644 1999 MOLECULAR AND CELLULAR BIOLOGY 19(12):7925-7932 Ceman S; Brown V; Warren ST Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex | 50 | 76 |
| 38 | 0 | 52 | 152 1995 PEDIATRICS 95(5):744-752 BAUMGARDNER TL; REISS AL; FREUND LS; ABRAMS MT SPECIFICATION OF THE NEUROBEHAVIORAL PHENOTYPE IN MALES WITH FRAGILE-X SYNDROME | 49 | 75 |
| 39 | 6 | 42 | 829 2001 AMERICAN JOURNAL OF MEDICAL GENETICS 98(2):161-167 Irwin SA; Patel B; Idupulapati M; Harris JB; Crisostomo RA; et al. Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: A quantitative examination | 48 | 75 |
| 40 | 3 | 10 | 903 2001 NEUROLOGY 57(1):127-130 Hagerman RJ; Leehey M; Heinrichs W; Tassone F; Wilson R; et al. Intention tremor, parkinsonism, and generalized brain atrophy in male carriers of fragile X | 45 | 74 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 41 | 7 | 37 | 481 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(25):15521-15527 Brown V; Small K; Lakkis L; Feng Y; Gunter C; et al. Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein | 45 | 69 |
| 42 | 27 | 62 | 1125 2003 CELL 112(3):317-327 Zalfa F; Giorgi M; Primerano B; Moro A; Di Penta A; et al. The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at Synapses | 37 | 69 |
| 43 | 4 | 39 | 244 1996 EMBO JOURNAL 15(19):5408-5414 Fridell RA; Benson RE; Hua J; Bogerd HP; Cullen BR A nuclear role for the fragile X mental retardation protein | 35 | 67 |
| 44 | 24 | 64 | 575 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 84(3):250-261 Tassone F; Hagerman RJ; Ikle DN; Dyer PN; Lampe M; et al. FMRP expression as a potential prognostic indicator in fragile X syndrome | 60 | 67 |
| 45 | 3 | 25 | 258 1996 HUMAN MOLECULAR GENETICS 5(6):809-813 Tamanini F; Meijer N; Verheij C; Willems PJ; Galjaard H; et al. FMRP is associated to the ribosomes via RNA | 48 | 66 |
| 46 | 1 | 32 | 58 1995 BIOCHEMISTRY 34(39):12803-12811 MITAS M; YU A; DILL J; HAWORTH IS THE TRINUCLEOTIDE REPEAT SEQUENCE D(CGG)(15) FORMS A HEAT-STABLE HAIRPIN CONTAINING G(SYN)CENTER-DOT-G(ANTI) BASE-PAIRS | 15 | 63 |
| 47 | 1 | 54 | 424 1997 PSYCHIATRY RESEARCH-NEUROIMAGING 75(1):31-48 Kates WR; Abrams MT; Kaufmann WE; Breiter SN; Reiss AL Reliability and validity of MRI measurement of the amygdala and hippocampus in children with fragile X syndrome | 20 | 63 |
| 48 | 7 | 36 | 911 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(13):7101-7106 Greenough WT; Klintsova AY; Irwin SA; Galvez R; Bates KE; et al. Synaptic regulation of protein synthesis and the fragile X protein | 42 | 63 |
| 49 | 55 | 179 | 965 2002 ANNUAL REVIEW OF NEUROSCIENCE 25:315-338 O'Donnell WT; Warren ST A decade of molecular studies of fragile X syndrome | 0 | 63 |
| 50 | 12 | 40 | 1058 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(11):7746-7750 Huber KM; Gallagher SM; Warren ST; Bear MF Altered synaptic plasticity in a mouse model of fragile X mental retardation | 35 | 61 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 51 | 0 | 125 | 52 1995 ANNUAL REVIEW OF NEUROSCIENCE 18:77-99 WARREN ST; ASHLEY CT TRIPLET REPEAT EXPANSION MUTATIONS - THE EXAMPLE OF FRAGILE-X SYNDROME | 26 | 58 |
| 52 | 3 | 60 | 390 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272(27):16783-16792 Bacolla A; Gellibolian R; Shimizu M; Amirhaeri S; Kang S; et al. Flexible DNA: Genetically unstable CTG center dot CAG and CGG center dot CCG from human hereditary neuromuscular disease genes | 3 | 57 |
| 53 | 14 | 74 | 791 2000 MOLECULAR AND CELLULAR BIOLOGY 20(22):8536-8547 Wan LL; Dockendorff TC; Jongens TA; Dreyfuss G Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein | 44 | 57 |
| 54 | 17 | 79 | 712 2000 CEREBRAL CORTEX 10(10):1038-1044 Irwin SA; Galvez R; Greenough WT Dendritic spine structural anomalies in fragile-X mental retardation syndrome | 35 | 55 |
| 55 | 0 | 42 | 57 1995 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 217(3):1015-1025 Xing GQ; Zhang LX; Zhang L; Heynen T; Yoshikawa T; et al. Rat PPAR delta contains a CGG triplet repeat and is prominently expressed in the thalamic nuclei | 0 | 54 |
| 56 | 9 | 38 | 162 1996 AMERICAN JOURNAL OF HUMAN GENETICS 59(6):1252-1261 Nolin SL; Lewis FA; Ye LL; Houck GE; Glicksman AE; et al. Familial transmission of the FMR1 CGG repeat | 43 | 54 |
| 57 | 46 | 197 | 496 1998 JOURNAL OF MEDICAL GENETICS 35(7):579-589 de Vries BBA; Halley DJJ; Oostra BA; Niermeijer MF The fragile X syndrome | 32 | 52 |
| 58 | 0 | 49 | 257 1996 HUMAN MOLECULAR GENETICS 5(3):319-330 Eichler EE; Macpherson JN; Murray A; Jacobs PA; Chakravarti A; et al. Haplotype and interspersion analysis of the FMR1 CGG repeat identifies two different mutational pathways for the origin of the fragile X syndrome | 32 | 51 |
| 59 | 17 | 36 | 912 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(15):8844-8849 Schenck A; Bardoni B; Moro A; Bagni C; Mandel JL A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P | 27 | 51 |
| 60 | 1 | 46 | 121 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(48):28970-28977 NADEL Y; WEISMANSHOMER P; FRY M THE FRAGILE-X SYNDROME SINGLE-STRAND D(CGG)(N) NUCLEOTIDE REPEATS READILY FOLD BACK TO FORM UNIMOLECULAR HAIRPIN STRUCTURES | 17 | 50 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 61 | 1 | 24 | 142 1995 NATURE GENETICS 10(4):483-485 LUGENBEEL KA; PEIER AM; CARSON NL; CHUDLEY AE; NELSON DL INTRAGENIC LOSS OF FUNCTION MUTATIONS DEMONSTRATE THE PRIMARY ROLE OF FMR1 IN FRAGILE-X SYNDROME | 34 | 50 |
| 62 | 5 | 28 | 468 1998 HUMAN MOLECULAR GENETICS 7(1):109-113 Chiurazzi P; Pomponi MG; Willemsen R; Oostra BA; Neri G In vitro reactivation of the FMR1 gene involved in fragile X syndrome | 23 | 50 |
| 63 | 5 | 44 | 270 1996 JOURNAL OF MOLECULAR BIOLOGY 258(4):614-626 Shimizu M; Gellibolian R; Oostra BA; Wells RD Cloning, characterization and properties of plasmids containing CGG triplet repeats from the FMR-1 gene | 14 | 49 |
| 64 | 1 | 27 | 283 1996 NUCLEIC ACIDS RESEARCH 24(4):784-792 Mariappan SVS; Catasti P; Chen X; Ratliff R; Moyzis RK; et al. Solution structures of the individual single strands of the fragile X DNA triplets (GCC)(n)center dot(GGC)(n) | 12 | 49 |
| 65 | 2 | 63 | 506 1998 NEUROLOGY 50(1):121-130 Mostofsky SH; Mazzocco MMM; Aakalu G; Warsofsky IS; Denckla MB; et al. Decreased cerebellar posterior vermis size in fragile X syndrome - Correlation with neurocognitive performance | 21 | 48 |
| 66 | 11 | 54 | 1011 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(40):37804-37810 Ohashi S; Koike K; Omori A; Ichinose S; Ohara S; et al. Identification of mRNA/protein (mRNP) complexes containing Pur alpha, mStaufen, Fragile X Protein, and myosin Va and their association with rough endoplasmic reticulum equipped with a kinesin motor | 18 | 48 |
| 67 | 1 | 29 | 398 1997 JOURNAL OF MEDICAL GENETICS 34(1):1-5 Morton JE; Bundey S; Webb TP; MacDonald F; Rindl PM; et al. Fragile X syndrome is less common than previously estimated | 28 | 47 |
| 68 | 11 | 39 | 618 1999 HUMAN MOLECULAR GENETICS 8(13):2557-2566 Bardoni B; Schenck A; Mandel JL A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein | 34 | 47 |
| 69 | 0 | 49 | 113 1995 HUMAN MOLECULAR GENETICS 4(1):45-49 DEGRAAFF E; ROUILLARD P; WILLEMS PJ; SMITS APT; ROUSSEAU F; et al. HOTSPOT FOR DELETIONS IN THE CGG REPEAT REGION OF FMR1 IN FRAGILE-X PATIENTS | 31 | 46 |
| 70 | 3 | 34 | 413 1997 NATURE STRUCTURAL BIOLOGY 4(9):712-716 Musco G; Kharrat A; Stier G; Fraternali F; Gibson TJ; et al. The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndrome | 7 | 46 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 71 | 14 | 47 | 874 2001 HUMAN MOLECULAR GENETICS 10(14):1449-1454 Kenneson A; Zhang FP; Hagedorn CH; Warren ST Reduced FMRP and increased FMR1 transcription is proportionally associated with CGG repeat number in intermediate-length and premutation carriers | 36 | 46 |
| 72 | 4 | 15 | 376 1997 HUMAN GENETICS 99(3):308-311 Willemsen R; Smits A; Mohkamsing S; vanBeerendonk H; deHaan A; et al. Rapid antibody test for diagnosing fragile X syndrome: A validation of the technique | 39 | 45 |
| 73 | 4 | 104 | 478 1998 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 28(5):393-405 Feinstein C; Reiss AL Autism: The point of view from fragile X studies | 18 | 45 |
| 74 | 11 | 74 | 643 1999 MOLECULAR AND CELLULAR BIOLOGY 19(8):5675-5684 White PJ; Borts RH; Hirst MC Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism | 12 | 45 |
| 75 | 3 | 20 | 185 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):241-245 Kooy RF; DHooge R; Reyniers E; Bakker CE; Nagels G; et al. Transgenic mouse model for the fragile X syndrome | 25 | 44 |
| 76 | 1 | 7 | 207 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):370-372 Partington MW; Moore DY; Turner GM Confirmation of early menopause in fragile X carriers | 26 | 44 |
| 77 | 8 | 40 | 498 1998 JOURNAL OF MOLECULAR BIOLOGY 275(1):3-16 Darlow JM; Leach DRF Secondary structures in d(CGG) and d(CCG) repeat tracts | 8 | 44 |
| 78 | 3 | 35 | 542 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 83(4):248-252 Weiler IJ; Greenough WT Synaptic synthesis of the Fragile X protein: Possible involvement in synapse maturation and elimination | 31 | 44 |
| 79 | 10 | 58 | 882 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(19):16439-16446 Kamath-Loeb AS; Loeb LA; Johansson E; Burgers PMJ; Fry M Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)(n) trinucleotide repeat sequence | 4 | 44 |
| 80 | 12 | 36 | 1066 2003 AMERICAN JOURNAL OF HUMAN GENETICS 72(4):869-878 Jacquemont S; Hagerman RJ; Leehey M; Grigsby J; Zhang L; et al. Fragile X premutation tremor/ataxia syndrome: Molecular, clinical, and neuroimaging correlates | 26 | 44 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 81 | 0 | 5 | 139 1995 LANCET 346(8970):309-310 CONWAY GS; HETTIARACHCHI S; MURRAY A; JACOBS PA FRAGILE-X PREMUTATIONS IN FAMILIAL PREMATURE OVARIAN FAILURE | 21 | 43 |
| 82 | 11 | 53 | 648 1999 NEUROSCIENCE 94(1):185-192 Paradee W; Melikian HE; Rasmussen DL; Kenneson A; Conn PJ; et al. Fragile X mouse: Strain effects of knockout phenotype and evidence suggesting deficient amygdala function | 23 | 42 |
| 83 | 1 | 21 | 160 1996 AMERICAN JOURNAL OF HUMAN GENETICS 58(5):906-913 Knight SJL; Ritchie RJ; Chakrabarti L; Cross G; Taylor GR; et al. A study of FRAXE in mentally retarded individuals referred for fragile X syndrome (FRAXA) testing in the United Kingdom | 12 | 41 |
| 84 | 0 | 50 | 265 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(40):24325-24328 Godde JS; Kass SU; Hirst MC; Wolffe AP Nucleosome assembly on methylated CGG triplet repeats in the Fragile X Mental Retardation gene 1 promoter | 5 | 41 |
| 85 | 9 | 69 | 420 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(9):4587-4592 Hansen RS; Canfield TK; Fjeld AD; Mumm S; Laird CD; et al. A variable domain of delayed replication in FRAXA fragile X chromosomes: X inactivation-like spread of late replication | 8 | 41 |
| 86 | 5 | 54 | 545 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 83(4):268-279 Miller LJ; McIntosh DN; McGrath J; Shyu V; Lampe M; et al. Electrodermal responses to sensory stimuli in individuals with fragile X syndrome: A preliminary report | 32 | 41 |
| 87 | 0 | 29 | 286 1996 PEDIATRICS 97(1):122-126 Hagerman RJ; Staley LW; OConner R; Lugenbeel K; Nelson D; et al. Learning-disabled males with a fragile X CGG expansion in the upper premutation size range | 29 | 40 |
| 88 | 2 | 28 | 479 1998 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 28(6):499-508 Bailey DB; Mesibov GB; Hatton DD; Clark RD; Roberts JE; et al. Autistic behavior in young boys with fragile X syndrome | 31 | 40 |
| 89 | 1 | 29 | 202 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):340-345 Sobesky WE; Taylor AK; Pennington BF; Bennetto L; Porter D; et al. Molecular/clinical correlations in females with fragile X | 31 | 39 |
| 90 | 12 | 50 | 616 1999 HUMAN MOLECULAR GENETICS 8(5):863-869 Tamanini F; Bontekoe C; Bakker CE; van Unen L; Anar B; et al. Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations | 30 | 39 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 91 | 56 | 93 | 976 2002 CURRENT OPINION IN GENETICS & DEVELOPMENT 12(3):284-293 Bardoni B; Mandel JL Advances in understanding of fragile X pathogenesis and FMRP function, and in identification of X linked mental retardation genes | 31 | 39 |
| 92 | 2 | 20 | 269 1996 JOURNAL OF MEDICAL GENETICS 33(12):1007-1010 deVries BBA; Jansen CCAM; Duits AA; Verheij C; Willemsen R; et al. Variable FMR1 gene methylation of large expansions leads to variable phenotype in three males from one fragile X family | 31 | 38 |
| 93 | 2 | 64 | 385 1997 HUMAN MOLECULAR GENETICS 6(11):1791-1801 Stoger R; Kajimura TM; Brown WT; Laird CD Epigenetic variation illustrated by DNA methylation patterns of the fragile-X gene FMR1 | 12 | 38 |
| 94 | 20 | 39 | 1308 2004 NATURE NEUROSCIENCE 7(2):113-117 Jin P; Zarnescu DC; Ceman S; Nakamoto M; Mowrey J; et al. Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway | 16 | 38 |
| 95 | 0 | 43 | 119 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(39):23090-23096 CHEN FM ACID-FACILITATED SUPRAMOLECULAR ASSEMBLY OF G-QUADRUPLEXES IN D(CGG)(4) | 10 | 37 |
| 96 | 12 | 52 | 1049 2002 NEURON 34(6):961-972 Morales J; Hiesinger PR; Schroeder AJ; Kume K; Verstreken P; et al. Drosophila fragile X protein, DFXR, regulates neuronal morphology and function in the brain | 28 | 37 |
| 97 | 9 | 47 | 547 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 83(4):286-295 Kaufmann WE; Abrams MT; Chen WM; Reiss AL Genotype, molecular phenotype, and cognitive phenotype: Correlations in fragile X syndrome | 30 | 36 |
| 98 | 0 | 65 | 3 1995 AMERICAN JOURNAL OF HUMAN GENETICS 56(5):1147-1155 FISCH GS; SNOW K; THIBODEAU SN; CHALIFAUX M; HOLDEN JJA; et al. THE FRAGILE-X PREMUTATION IN CARRIERS AND ITS EFFECT ON MUTATION SIZE IN OFFSPRING | 28 | 35 |
| 99 | 1 | 25 | 115 1995 HUMAN MOLECULAR GENETICS 4(12):2199-2208 EICHLER EE; HAMMOND HA; MACPHERSON JN; WARD PA; NELSON DL POPULATION SURVEY OF THE HUMAN FMR1 CGG REPEAT SUBSTRUCTURE SUGGESTS BIASED POLARITY FOR THE LOSS OF AGG INTERRUPTIONS | 20 | 35 |
| 100 | 6 | 33 | 706 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 275(3):973-980 Sung YJ; Conti J; Currie JR; Brown WT; Denman RB RNAs that interact with the Fragile X syndrome RNA binding protein FMRP | 27 | 35 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 101 | 7 | 32 | 723 2000 EPILEPSIA 41(1):19-23 Musumeci SA; Bosco P; Calabrese G; Bakker C; De Sarro GB; et al. Audiogenic seizures susceptibility in transgenic mice with fragile X syndrome | 26 | 35 |
| 102 | 3 | 37 | 186 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):246-251 Godfraind JM; Reyniers E; DeBoulle K; DHooge R; DeDeyn PP; et al. Long-term potentiation in the hippocampus of fragile X knockout mice | 25 | 34 |
| 103 | 1 | 41 | 204 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):356-361 Fisch GS; Simensen R; Tarleton J; Chalifoux M; Holden JJ; et al. Longitudinal study of cognitive abilities and adaptive behavior levels in fragile X males: A prospective multicenter analysis | 27 | 34 |
| 104 | 5 | 35 | 383 1997 HUMAN MOLECULAR GENETICS 6(7):971-979 Moutou C; Vincent MC; Biancalana V; Mandel JL Transition from premutation to full mutation in fragile X syndrome is likely to be prezygotic | 23 | 34 |
| 105 | 12 | 40 | 698 2000 AMERICAN JOURNAL OF MEDICAL GENETICS 97(3):195-203 Tassone F; Hagerman RJ; Chamberlain WD; Hagerman PJ Transcription of the FMR1 gene in individuals with fragile X syndrome | 29 | 34 |
| 106 | 8 | 43 | 906 2001 NEUROSCIENCE 103(4):1043-1050 Chen L; Toth M Fragile X mice develop sensory hyperreactivity to auditory stimuli | 21 | 34 |
| 107 | 13 | 40 | 1005 2002 HUMAN MOLECULAR GENETICS 11(4):371-378 Dombrowski C; Levesque S; Morel ML; Rouillard P; Morgan K; et al. Premutation and intermediate-size FMR1 alleles in 10,572 males from the general population: Loss of an AGG interruption is a late event in the generation of fragile X syndrome alleles | 22 | 34 |
| 108 | 33 | 55 | 1193 2003 TRENDS IN BIOCHEMICAL SCIENCES 28(3):152-158 Jin P; Warren ST New insights into fragile X syndrome: from molecules to neurobehaviors | 18 | 34 |
| 109 | 12 | 29 | 470 1998 HUMAN MOLECULAR GENETICS 7(13):2121-2128 Khandjian EW; Bardoni B; Corbin F; Sittler A; Giroux S; et al. Novel isoforms of the fragile X related protein FXR1P are expressed during myogenesis | 24 | 33 |
| 110 | 4 | 36 | 473 1998 HUMAN REPRODUCTION 13(5):1184-1187 Conway GS; Payne NN; Webb J; Murray A; Jacobs PA Fragile X premutation screening in women with premature ovarian failure | 9 | 33 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 111 | 1 | 54 | 5 1995 AMERICAN JOURNAL OF HUMAN GENETICS 57(3):609-618 DEGRAAFF E; WILLEMSEN R; ZHONG N; DEDIESMULDERS CEM; BROWN WT; et al. INSTABILITY OF THE CGG REPEAT AND EXPRESSION OF THE FMR1 PROTEIN IN A MALE FRAGILE-X PATIENT WITH A LUNG-TUMOR | 26 | 32 |
| 112 | 1 | 21 | 173 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(1):27-30 Carrel L; Willard HF An assay for X inactivation based on differential methylation at the fragile X locus, FMR1 | 1 | 32 |
| 113 | 0 | 18 | 201 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):334-339 Franke P; Maier W; Hautzinger M; Weiffenbach O; Gansicke M; et al. Fragile-X carrier females: Evidence for a distinct psychopathological phenotype? | 23 | 32 |
| 114 | 4 | 23 | 436 1998 AMERICAN JOURNAL ON MENTAL RETARDATION 103(1):29-39 Bailey DB; Hatton DD; Skinner M Early developmental trajectories of males with fragile X syndrome | 30 | 32 |
| 115 | 7 | 51 | 495 1998 JOURNAL OF MEDICAL GENETICS 35(2):103-111 Wohrle D; Salat U; Glaser D; Mucke J; Meisel-Stosiek M; et al. Unusual mutations in high functioning fragile X males: apparent instability of expanded unmethylated CGG repeats | 19 | 32 |
| 116 | 0 | 92 | 49 1995 AMERICAN JOURNAL OF MEDICAL GENETICS 60(6):480-493 Schapiro MB; Murphy DGM; Hagerman RJ; Azari NP; Alexander GE; et al. Adult fragile X syndrome: Neuropsychology, brain anatomy, and metabolism | 21 | 31 |
| 117 | 0 | 34 | 147 1995 NUCLEIC ACIDS RESEARCH 23(11):1876-1881 MITCHELL JE; NEWBURY SF; MCCLELLAN JA COMPACT STRUCTURES OF D(CNG)(N) OLIGONUCLEOTIDES IN SOLUTION AND THEIR POSSIBLE RELEVANCE TO FRAGILE-X AND RELATED HUMAN GENETIC-DISEASES | 6 | 31 |
| 118 | 6 | 28 | 653 2000 AMERICAN JOURNAL OF HUMAN GENETICS 66(2):413-418 Hundscheid RDL; Sistermans EA; Thomas CMG; Braat DDM; Straatman H; et al. Imprinting effect in premature ovarian failure confined to paternally inherited fragile X premutations | 15 | 31 |
| 119 | 0 | 43 | 722 2000 EMBO JOURNAL 19(17):4745-4758 Yaremchuk A; Cusack S; Tukalo M Crystal structure of a eukaryote/archaeon-like prolyl-tRNA synthetase and its complex with tRNA(Pro)(CGG) | 0 | 31 |
| 120 | 16 | 40 | 728 2000 EXPERIMENTAL CELL RESEARCH 258(1):162-170 Bakker CE; Otero YD; Bontekoe C; Raghoe P; Luteijn T; et al. Immunocytochemical and biochemical characterization of FMRP, FXR1P, and FXR2P in the mouse | 22 | 31 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 121 | 25 | 57 | 1006 2002 HUMAN MOLECULAR GENETICS 11(24):3007-3017 Mazroui R; Huot ME; Tremblay S; Filion C; Labelle Y; et al. Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression | 24 | 31 |
| 122 | 0 | 37 | 2 1995 AMERICAN JOURNAL OF HUMAN GENETICS 56(5):1042-1051 QUAN F; ZONANA J; GUNTER K; PETERSON KL; MAGENIS RE; et al. AN ATYPICAL CASE OF FRAGILE-X SYNDROME CAUSED BY A DELETION THAT INCLUDES THE FMRI GENE | 19 | 30 |
| 123 | 3 | 24 | 227 1996 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 225(1):27-33 Willemsen R; Bontekoe C; Tamanini F; Galjaard H; Hoogeveen A; et al. Association of FMRP with ribosomal precursor particles in the nucleolus | 25 | 30 |
| 124 | 16 | 33 | 697 2000 AMERICAN JOURNAL OF MEDICAL GENETICS 97(3):189-194 Sherman SL Premature ovarian failure in the fragile X syndrome | 15 | 30 |
| 125 | 10 | 41 | 743 2000 HUMAN REPRODUCTION 15(1):197-202 Marozzi A; Vegetti W; Manfredini E; Tibiletti MG; Testa G; et al. Association between idiopathic premature ovarian failure and fragile X premutation | 10 | 30 |
| 126 | 10 | 43 | 650 1999 RNA-A PUBLICATION OF THE RNA SOCIETY 5(9):1248-1258 Adinolfi S; Bagni C; Musco G; Gibson T; Mazzarella L; et al. Dissecting FMR1, the protein responsible for fragile X syndrome, in its structural and functional domains | 22 | 29 |
| 127 | 9 | 38 | 708 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 279(3):904-908 Ceman S; Nelson R; Warren ST Identification of mouse YB1/p50 as a component of the FMRP-associated mRNP particle | 21 | 29 |
| 128 | 0 | 20 | 132 1995 JOURNAL OF MEDICAL GENETICS 32(3):170-173 WANG Q; GREEN E; BOBROW M; MATHEW CG A RAPID, NONRADIOACTIVE SCREENING-TEST FOR FRAGILE-X MUTATIONS AT THE FRAXA AND FRAXE LOCI | 17 | 28 |
| 129 | 4 | 24 | 177 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(1):191-195 Brown WT; Nolin S; Houck G; Ding XH; Glicksman A; et al. Prenatal diagnosis and carrier screening for fragile X by PCR | 20 | 28 |
| 130 | 7 | 33 | 415 1997 NEUROBIOLOGY OF DISEASE 4(5):329-336 Bardoni B; Sittler A; Shen Y; Mandel JL Analysis of domains affecting intracellular localization of the FMRP protein | 22 | 28 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 131 | 16 | 136 | 586 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 88(1):11-24 Kaufmann WE; Reiss AL Molecular and cellular genetics of fragile X syndrome | 16 | 28 |
| 132 | 4 | 28 | 188 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):261-265 Zhong N; Ju WN; Pietrofesa J; Wang DW; Dobkin C; et al. Fragile X ''gray zone'' alleles: AGG patterns, expansion risks, and associated haplotypes | 15 | 27 |
| 133 | 3 | 25 | 214 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):428-433 Meadows KL; Pettay D; Newman J; Hersey J; Ashley AE; et al. Survey of the fragile X syndrome and the fragile X E syndrome in a special education needs population | 13 | 27 |
| 134 | 2 | 55 | 254 1996 HUMAN GENETICS 98(2):151-157 Kramer PR; Pearson CE; Sinden RR Stability of triplet repeats of myotonic dystrophy and fragile X loci in human mutator mismatch repair cell lines | 2 | 27 |
| 135 | 4 | 41 | 304 1997 AMERICAN JOURNAL OF HUMAN GENETICS 60(1):103-112 FalikZaccai TC; Shachak E; Yalon M; Lis Z; Borochowitz Z; et al. Predisposition to the fragile X syndrome in Jews of Tunisian descent is due to the absence of AGG interruptions on a rare Mediterranean haplotype | 17 | 27 |
| 136 | 3 | 13 | 797 2000 NEUROBIOLOGY OF LEARNING AND MEMORY 73(1):87-93 Irwin SA; Swain RA; Christmon CA; Chakravarti A; Weiler IJ; et al. Evidence for altered Fragile-X mental retardation protein expression in response to behavioral stimulation | 23 | 27 |
| 137 | 10 | 47 | 961 2002 AMERICAN JOURNAL OF NEURORADIOLOGY 23(10):1757-1766 Brunberg JA; Jacquemont S; Hagerman RJ; Berry-Kravis EM; Grigsby J; et al. Fragile X premutation carriers: Characteristic MR imaging findings of adult male patients with progressive cerebellar and cognitive dysfunction | 17 | 27 |
| 138 | 0 | 38 | 83 1995 DEVELOPMENTAL BRAIN DYSFUNCTION 8(4-6):270-279 Belser RC; Sudhalter V Arousal difficulties in males with fragile X syndrome: A preliminary report | 21 | 26 |
| 139 | 3 | 59 | 181 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(1):209-215 Chiurazzi P; Genuardi M; Kozak L; GiovannucciUzielli ML; Bussani C; et al. Fragile X founder chromosomes in Italy: A few initial events and possible explanation for their heterogeneity | 17 | 26 |
| 140 | 5 | 43 | 183 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(1):226-233 Zhong N; Kajanoja E; Smits B; Pietrofesa J; Curley D; et al. Fragile X founder effects and new mutations in Finland | 14 | 26 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 141 | 7 | 35 | 469 1998 HUMAN MOLECULAR GENETICS 7(12):1935-1946 Gunter C; Paradee W; Crawford DC; Meadows KA; Newman J; et al. Re-examination of factors associated with expansion of CGG repeats using a single nucleotide polymorphism in FMR1 | 14 | 26 |
| 142 | 5 | 27 | 578 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 84(3):300-303 Uzielli MLG; Guarducci S; Lapi E; Cecconi A; Ricci U; et al. Premature ovarian failure (POF) and fragile X premutation females: From POF to fragile X carrier identification, from fragile X carrier diagnosis to POF association data | 14 | 26 |
| 143 | 6 | 23 | 649 1999 PRENATAL DIAGNOSIS 19(13):1223-1230 Sermon K; Seneca S; Vanderfaeillie A; Lissens W; Joris H; et al. Preimplantation diagnosis for fragile X syndrome based on the detection of the non-expanded paternal and maternal CGG | 2 | 26 |
| 144 | 10 | 35 | 687 2000 AMERICAN JOURNAL OF MEDICAL GENETICS 94(3):232-236 Tassone F; Hagerman RJ; Loesch DZ; Lachiewicz A; Taylor AK; et al. Fragile X males with unmethylated, full mutation trinucleotide repeat expansions have elevated levels of FMR1 messenger RNA | 20 | 26 |
| 145 | 10 | 50 | 180 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(1):203-208 Chiurazzi P; Macpherson J; Sherman S; Neri G Significance of linkage disequilibrium between the fragile X locus and its flanking markers | 18 | 25 |
| 146 | 3 | 61 | 388 1997 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 27(4):415-435 Mazzocco MMM; Kates WR; Baumgardner TL; Freund LS; Reiss AL Autistic behaviors among girls with fragile X syndrome | 20 | 25 |
| 147 | 82 | 154 | 870 2001 GENETICS IN MEDICINE 3(5):359-371 Crawford DC; Acuna JM; Sherman SL FMR1 and the fragile X syndrome: Human genome epidemiology review | 17 | 25 |
| 148 | 29 | 51 | 975 2002 CURRENT OPINION IN GENETICS & DEVELOPMENT 12(3):278-283 Hagerman RJ; Hagerman PJ The fragile X premutation: into the phenotypic fold | 15 | 25 |
| 149 | 13 | 26 | 1178 2003 NEURON 37(4):555-558 Antar LN; Bassell GJ Sunrise at the synapse: The FMRP mRNP shaping the synaptic interface | 11 | 25 |
| 150 | 1 | 43 | 263 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(8):4327-4334 Deissler H; BehnKrappa A; Doerfler W Purification of nuclear proteins from human HeLa cells that bind specifically to the unstable tandem repeat (CGG), in the human FMR1 gene | 11 | 24 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 151 | 2 | 19 | 379 1997 HUMAN GENETICS 100(5-6):564-568 Larsen LA; Gronskov K; NorgaardPedersen B; BrondumNielsen K; Hasholt L; et al. High-throughput analysis of fragile X (CGG)(n) alleles in the normal and premutation range by PCR amplification and automated capillary electrophoresis | 8 | 24 |
| 152 | 3 | 31 | 417 1997 NUCLEIC ACIDS RESEARCH 25(14):2883-2887 Sandberg G; Schalling M Effect of in vitro promoter methylation and CGG repeat expansion on FMR-1 expression | 10 | 24 |
| 153 | 5 | 24 | 516 1999 AMERICAN JOURNAL OF HUMAN GENETICS 65(1):98-103 Willemsen R; Anar B; Otero YD; de Vries BBA; Hilhorst-Hofstee Y; et al. Noninvasive test for fragile X syndrome, using hair root analysis | 22 | 24 |
| 154 | 18 | 40 | 573 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 84(3):233-239 Taylor AK; Tassone F; Dyer PN; Hersch SM; Harris JB; et al. Tissue heterogeneity of the FMR1 mutation in a high-functioning male with fragile X syndrome | 17 | 24 |
| 155 | 34 | 117 | 790 2000 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 6(2):96-106 Mazzocco MMM Advances in research on the fragile X syndrome | 20 | 24 |
| 156 | 8 | 54 | 837 2001 AMERICAN JOURNAL OF PSYCHIATRY 158(7):1040-1051 Kwon H; Menon V; Eliez S; Warsofsky IS; White CD; et al. Functional neuroanatomy of visuospatial working memory in fragile X syndrome: Relation to behavioral and molecular measures | 11 | 24 |
| 157 | 10 | 34 | 888 2001 JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS 22(6):409-417 Rogers SJ; Wehner EA; Hagerman R The behavioral phenotype in fragile X: Symptoms of autism in very young children with fragile X syndrome, idiopathic autism, and other developmental disorders | 13 | 24 |
| 158 | 15 | 43 | 1034 2002 MOLECULAR AND CELLULAR BIOLOGY 22(23):8332-8341 Otero YD; Severijnen LA; van Cappellen G; Schrier M; Oostra B; et al. Transport of fragile X mental retardation protein via granules in neurites of PC12 cells | 17 | 24 |
| 159 | 0 | 29 | 262 1996 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 26(3):287-301 Dykens E; Ort S; Cohen I; Finucane B; Spiridigliozzi G; et al. Trajectories and profiles of adaptive behavior in males with fragile X syndrome: Multicenter studies | 19 | 23 |
| 160 | 1 | 37 | 264 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(38):22937-22940 Wang YH; Griffith J Methylation of expanded CCG triplet repeat DNA from fragile X syndrome patients enhances nucleosome exclusion | 4 | 23 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 161 | 1 | 15 | 363 1997 CLINICAL GENETICS 52(3):147-154 Hecimovic S; Barisic I; Muller A; Petkovic I; Baric I; et al. Expand long PCR for fragile X mutation detection | 8 | 23 |
| 162 | 5 | 37 | 574 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 84(3):245-249 Reyniers E; Martin JJ; Cras P; Van Marck E; Handig I; et al. Postmortem examination of two fragile X brothers with an FMR1 full mutation | 19 | 23 |
| 163 | 16 | 36 | 592 1999 BIOCHEMICAL JOURNAL 343:517-523 Tamanini F; van Unen L; Bakker C; Sacchi N; Galjaard H; et al. Oligomerization properties of fragile-X mental-retardation protein (FMRP) and the fragile-X-related proteins FXR1P and FXR2P | 20 | 23 |
| 164 | 14 | 38 | 713 2000 CEREBRAL CORTEX 10(10):1045-1052 Braun K; Segal M FMRP involvement in formation of synapses among cultured hippocampal neurons | 21 | 23 |
| 165 | 4 | 28 | 881 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(6):4357-4364 Kumari D; Usdin K Interaction of the transcription factors USF1, USF2, and alpha-Pal/Nrf-1 with the FMR1 promoter - Implications for Fragile X mental retardation syndrome | 15 | 23 |
| 166 | 8 | 30 | 1111 2003 ARCHIVES OF NEUROLOGY 60(1):117-121 Leehey MA; Munhoz RP; Lang AE; Brunberg JA; Grigsby J; et al. The fragile X premutation presenting as essential tremor | 12 | 23 |
| 167 | 21 | 64 | 1180 2003 NEURON 38(6):887-898 Schenck A; Bardoni B; Langmann C; Harden N; Mandel JL; et al. CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein | 11 | 23 |
| 168 | 6 | 35 | 1181 2003 NEURON 39(5):739-747 Jin P; Zarnescu DC; Zhang FP; Pearson CE; Lucchesi JC; et al. RNA-mediated neurodegeneration caused by the fragile X premutation rCGG repeats in Drosophila | 10 | 23 |
| 169 | 0 | 33 | 81 1995 DEVELOPMENTAL BRAIN DYSFUNCTION 8(4-6):242-251 Freund LS; Peebles CD; Aylward E; Reiss AL Preliminary report on cognitive and adaptive behaviors of preschool-aged males with fragile X | 17 | 22 |
| 170 | 0 | 21 | 268 1996 JOURNAL OF MEDICAL GENETICS 33(5):376-378 Wang ZM; Taylor AK; Bridge JA FMR1 fully expanded mutation with minimal methylation in a high functioning fragile X male | 17 | 22 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 171 | 0 | 14 | 273 1996 JOURNAL OF PEDIATRICS 129(4):611-614 Giangreco CA; Steele MW; Aston CE; Cummins JH; Wenger SL A simplified six-item checklist for screening for fragile X syndrome in the pediatric population | 11 | 22 |
| 172 | 13 | 43 | 337 1997 AMERICAN JOURNAL OF HUMAN GENETICS 61(6):1362-1369 Kenneson A; Cramer DW; Warren ST Fragile X premutations are not a major cause of early menopause | 13 | 22 |
| 173 | 9 | 25 | 342 1997 AMERICAN JOURNAL OF MEDICAL GENETICS 72(4):430-434 Hammond LS; Macias MM; Tarleton JC; Pai GS Fragile X syndrome and deletions in FMR1: New case and review of the literature | 15 | 22 |
| 174 | 11 | 42 | 429 1998 AMERICAN JOURNAL OF HUMAN GENETICS 63(3):776-785 Ashley-Koch AE; Robinson H; Glicksman AE; Nolin SL; Schwartz CE; et al. Examination of factors associated with instability of the FMR1 CGG repeat | 15 | 22 |
| 175 | 26 | 98 | 593 1999 BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE 77(4):331-342 Khandjian EW Biology of the fragile X mental retardation protein, an RNA-binding protein | 14 | 22 |
| 176 | 12 | 40 | 811 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(2):351-360 Toledano-Alhadef H; Basel-Vanagaite L; Magal N; Davidov B; Ehrlich S; et al. Fragile-X carrier screening and the prevalence of premutation and full-mutation carriers in Israel | 13 | 22 |
| 177 | 10 | 33 | 880 2001 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 31(2):165-174 Bailey DB; Hatton DD; Skinner M; Mesibov G Autistic behavior, FMR1 protein, and developmental trajectories in young males with fragile X syndrome | 16 | 22 |
| 178 | 8 | 19 | 895 2001 JOURNAL OF MEDICAL GENETICS 38(7):453-456 Tassone F; Hagerman RJ; Taylor AK; Hagerman PJ A majority of fragile X males with methylated, full mutation alleles have significant levels of FMR1 messenger RNA | 16 | 22 |
| 179 | 0 | 30 | 54 1995 ARCHIVES OF DISEASE IN CHILDHOOD 72(1):33-37 SLANEY SF; WILKIE AOM; HIRST MC; CHARLTON R; MCKINLEY M; et al. DNA TESTING FOR FRAGILE-X SYNDROME IN SCHOOLS FOR LEARNING-DIFFICULTIES | 13 | 21 |
| 180 | 1 | 51 | 391 1997 JOURNAL OF CLINICAL INVESTIGATION 100(2):331-338 Jakala P; Hanninen T; Ryynanen M; Laakso M; Partanen K; et al. Fragile-X: Neuropsychological test performance, CGG triplet repeat lengths, and hippocampal volumes | 13 | 21 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 181 | 7 | 62 | 463 1998 GENOMICS 50(2):229-240 Lavedan C; Grabczyk E; Usdin K; Nussbaum RL Long uninterrupted CGG repeats within the first exon of the human FMR1 gene are not intrinsically unstable in transgenic mice | 17 | 21 |
| 182 | 7 | 29 | 499 1998 JOURNAL OF MOLECULAR BIOLOGY 275(1):17-23 Darlow JM; Leach DRF Evidence for two preferred hairpin folding patterns in d(CGG).d(CCG) repeat tracts in vivo | 3 | 21 |
| 183 | 7 | 33 | 607 1999 EUROPEAN JOURNAL OF HUMAN GENETICS 7(5):526-532 Kooy RF; Reyniers E; Verhoye M; Sijbers J; Bakker CE; et al. Neuroanatomy of the fragile X knockout mouse brain studied using in vivo high resolution magnetic resonance imaging | 9 | 21 |
| 184 | 54 | 116 | 695 2000 AMERICAN JOURNAL OF MEDICAL GENETICS 97(2):153-163 Bardoni B; Mandel JL; Fisch GS FMR1 gene and fragile X syndrome | 12 | 21 |
| 185 | 24 | 45 | 796 2000 MOLECULAR MEDICINE TODAY 6(5):193-198 Kooy RF; Willemsen R; Oostra BA Fragile X syndrome at the turn of the century | 15 | 21 |
| 186 | 3 | 47 | 799 2000 NEUROPSYCHOLOGIA 38(9):1261-1270 Munir F; Cornish KM; Wilding J A neuropsychological profile of attention deficits in young males with fragile X syndrome | 17 | 21 |
| 187 | 15 | 39 | 1065 2003 AMERICAN JOURNAL OF HUMAN GENETICS 72(2):454-464 Nolin SL; Brown WT; Glicksman A; Houck GE; Gargano AD; et al. Expansion of the fragile X CGG repeat in females with premutation or intermediate alleles | 13 | 21 |
| 188 | 2 | 42 | 41 1995 AMERICAN JOURNAL OF HUMAN GENETICS 57(6):1414-1425 ASHLEY AE; SHERMAN SL POPULATION-DYNAMICS OF A MEIOTIC MITOTIC EXPANSION MODEL FOR THE FRAGILE-X SYNDROME | 18 | 20 |
| 189 | 5 | 37 | 563 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 84(3):184-190 Patsalis PC; Sismani C; Hettinger JA; Boumba I; Georgiou I; et al. Molecular screening of fragile X (FRAXA) and FRAXE mental retardation syndromes in the Hellenic population of Greece and Cyprus: Incidence, genetic variation, and stability | 10 | 20 |
| 190 | 8 | 62 | 736 2000 HUMAN MOLECULAR GENETICS 9(1):93-100 Balakumaran BS; Freudenreich CH; Zakian VA CGG/CCG repeats exhibit orientation-dependent instability and orientation-independent fragility in Saccharomyces cerevisiae | 0 | 20 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 191 | 19 | 75 | 1036 2002 MOLECULAR AND CELLULAR NEUROSCIENCE 19(2):138-151 Li JX; Pelletier MR; Velazquez JLP; Carlen PL Reduced cortical synaptic plasticity and GluR1 expression associated with fragile X mental retardation protein deficiency | 18 | 20 |
| 192 | 0 | 37 | 84 1995 DEVELOPMENTAL BRAIN DYSFUNCTION 8(4-6):280-292 Sobesky WE; Porter D; Pennington BF; Hagerman RJ Dimensions of shyness in fragile X females | 14 | 19 |
| 193 | 0 | 13 | 191 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):274-277 Steyaert J; Borghgraef M; Legius E; Fryns JP Molecular-intelligence correlations in young fragile X males with a mild CGG repeat expansion in the FMR1 gene | 15 | 19 |
| 194 | 2 | 64 | 378 1997 HUMAN GENETICS 100(3-4):407-414 Lavedan CN; Garrett L; Nussbaum RL Trinucleotide repeats (CGG)(22)TGG(CGG)(43)TGG(CGG)(21) from the fragile X gene remain stable in transgenic mice | 14 | 19 |
| 195 | 0 | 28 | 405 1997 JOURNAL OF MOLECULAR BIOLOGY 267(5):1171-1185 Tippin DB; Sundaralingam M Nine polymorphic crystal structures of d(CCGGGCCCGG), d(CCGGGCCm(5)CGG), d(Cm(5)CGGGCCm(5)CGG) and d(CCGGGCC(Br)(5)CGG) in three different conformations: Effects of spermine binding and methylation on the bending and condensation of A-DNA | 0 | 19 |
| 196 | 3 | 41 | 552 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 83(4):313-317 Hagerman RJ; Hills J; Scharfenaker S; Lewis H Fragile X syndrome and selective mutism | 12 | 19 |
| 197 | 1 | 6 | 554 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 83(4):322-325 Allingham-Hawkins SJ; Babul-Hirji R; Chitayat D; Holden JJA; Yang KT; et al. Fragile X premutation is a significant risk factor for premature ovarian failure: The international collaborative POF in fragile X study - Preliminary data | 11 | 19 |
| 198 | 4 | 54 | 605 1999 EPILEPSIA 40(8):1092-1099 Musumeci SA; Hagerman RJ; Ferri R; Bosco P; Dalla Bernardina B; et al. Epilepsy and EEG findings in males with fragile X syndrome | 10 | 19 |
| 199 | 8 | 46 | 692 2000 AMERICAN JOURNAL OF MEDICAL GENETICS 95(4):307-315 Gould EL; Loesch DZ; Martin MJ; Hagerman RJ; Armstrong SM; et al. Melatonin profiles and sleep characteristics in boys with fragile X syndrome: A preliminary study | 13 | 19 |
| 200 | 4 | 41 | 748 2000 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 30(1):49-59 Bailey DB; Hatton DD; Mesibov G; Ament N; Skinner M Early development, temperament, and functional impairment in autism and fragile X syndrome | 16 | 19 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 201 | 14 | 56 | 1145 2003 HUMAN MOLECULAR GENETICS 12(9):949-959 Willemsen R; Hoogeveen-Westerveld M; Reis S; Holstege J; Severijnen LAWFM; et al. The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome | 11 | 19 |
| 202 | 1 | 40 | 143 1995 NATURE GENETICS 11(3):301-308 EICHLER EE; KUNST CB; LUGENBEEL KA; RYDER OA; DAVISON D; et al. EVOLUTION OF THE CRYPTIC FMR1 CGG REPEAT | 11 | 18 |
| 203 | 1 | 12 | 175 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(1):181-183 Spence WC; Black SH; Fallon L; Maddalena A; Cummings E; et al. Molecular fragile X screening in normal populations | 13 | 18 |
| 204 | 2 | 45 | 182 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(1):220-225 Eichler EE; Nelson DL Genetic variation and evolutionary stability of the FMR1 CGG repeat in six closed human populations | 14 | 18 |
| 205 | 0 | 21 | 189 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):266-267 Wohrle D; Schwemmle S; Steinbach P DNA methylation and triplet repeat stability: New proposals addressing actual questions on the CGG repeat of fragile X syndrome | 11 | 18 |
| 206 | 3 | 35 | 193 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):287-292 Brown WT; Houck GE; Ding XH; Zhong N; Nolin S; et al. Reverse mutations in the fragile X syndrome | 11 | 18 |
| 207 | 7 | 33 | 371 1997 EUROPEAN JOURNAL OF HUMAN GENETICS 5(5):293-298 Bontekoe CJM; deGraaff E; Nieuwenhuizen IM; Willemsen R; Oostra BA FMR1 premutation allele (CGG)(81) is stable in mice | 16 | 18 |
| 208 | 3 | 41 | 491 1998 JOURNAL OF INTELLECTUAL DISABILITY RESEARCH 42:490-499 Turk J; Cornish K Face recognition and emotion perception in boys with fragile-X syndrome | 12 | 18 |
| 209 | 5 | 39 | 500 1998 JOURNAL OF MOLECULAR BIOLOGY 283(1):111-120 Mariappan SVS; Silks LA; Bradbury EM; Gupta G Fragile X DNA triplet repeats, (GCC)(n), form hairpins with single hydrogen-bonded cytosine center dot cytosine mispairs at the CpG sites: Isotope-edited nuclear magnetic resonance spectroscopy on (GCC)(n) with selective (15)N4-labeled cytosine bases | 4 | 18 |
| 210 | 4 | 11 | 509 1998 NEUROREPORT 9(3):477-481 Steward O; Bakker CE; Willems PJ; Oostra BA No evidence for disruption of normal patterns of mRNA localization in dendrites or dendritic transport of recently synthesized mRNA in FMR1 knockout mice, a model for human fragile-X mental retardation syndrome | 12 | 18 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 211 | 5 | 23 | 606 1999 EUROPEAN JOURNAL OF HUMAN GENETICS 7(2):212-216 Ryynanen M; Heinonen S; Makkonen M; Kajanoja E; Mannermaa A; et al. Feasibility and acceptance of screening for fragile X mutations in low-risk pregnancies | 13 | 18 |
| 212 | 16 | 52 | 654 2000 AMERICAN JOURNAL OF HUMAN GENETICS 66(2):480-493 Crawford DC; Schwartz CE; Meadows KL; Newman JL; Taft LF; et al. Survey of the fragile X syndrome CGG repeat and the short-tendem-repeat and single-nucleotide-polymorphism haplotypes in an African American population | 9 | 18 |
| 213 | 1 | 4 | 1143 2003 HUMAN GENETICS 112(5-6):619-620 Macpherson J; Waghorn A; Hammans S; Jacobs P Observation of an excess of fragile-X premutations in a population of males referred with spinocerebellar ataxia | 9 | 18 |
| 214 | 0 | 39 | 64 1995 BRAIN & DEVELOPMENT 17(5):317-321 NANBA E; KOHNO Y; MATSUDA A; YANO M; SATO C; et al. NONRADIOACTIVE DNA DIAGNOSIS FOR THE FRAGILE-X SYNDROME IN MENTALLY-RETARDED JAPANESE MALES | 8 | 17 |
| 215 | 6 | 47 | 389 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272(27):16761-16768 Deissler H; Wilm M; Genc B; Schmitz B; Ternes T; et al. Rapid protein sequencing by tandem mass spectrometry and cDNA cloning of p20-CGGBP - A novel protein that binds to the unstable triplet repeat 5'-d(CGG)(n)-3' in the human FMR1 gene | 5 | 17 |
| 216 | 12 | 92 | 409 1997 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 3(4):313-322 Abbeduto L; Hagerman RJ Language and communication in fragile X syndrome | 10 | 17 |
| 217 | 0 | 42 | 476 1998 JOURNAL OF APPLIED RESEARCH IN INTELLECTUAL DISABILITIES 11(3):175-191 Turk J Fragile X syndrome and attentional deficits | 12 | 17 |
| 218 | 1 | 4 | 656 2000 AMERICAN JOURNAL OF HUMAN GENETICS 67(1):253-254 Murray A; Ennis S; Morton N No evidence for parent of origin influencing premature ovarian failure in fragile X premutation carriers | 9 | 17 |
| 219 | 12 | 37 | 794 2000 MOLECULAR BRAIN RESEARCH 80(1):17-25 Todd PK; Mack KJ Sensory stimulation increases cortical expression of the fragile X mental retardation protein in vivo | 17 | 17 |
| 220 | 7 | 17 | 806 2000 PRENATAL DIAGNOSIS 20(8):611-614 Pesso R; Berkenstadt H; Cuckle H; Gak E; Peleg L; et al. Screening for fragile X syndrome in women of reproductive age | 13 | 17 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 221 | 4 | 37 | 973 2002 CURRENT BIOLOGY 12(15):1331-1335 Inoue SB; Shimoda M; Nishinokubi I; Siomi MC; Okamura M; et al. A role for the Drosophila fragile X-related gene in circadian output | 13 | 17 |
| 222 | 0 | 40 | 134 1995 JOURNAL OF MEDICAL GENETICS 32(10):764-769 DEVRIES BBA; ROBINSON H; STOLTEDIJKSTRA I; GI CVTP; DIJKSTRA PF; et al. GENERAL OVERGROWTH IN THE FRAGILE-X SYNDROME - VARIABILITY IN THE PHENOTYPIC-EXPRESSION OF THE FMR1 GENE MUTATION | 6 | 16 |
| 223 | 0 | 70 | 156 1995 SEMINARS IN CELL BIOLOGY 6(1):5-11 NELSON DL THE FRAGILE-X SYNDROMES | 4 | 16 |
| 224 | 3 | 21 | 187 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):256-260 Sherman SL; Meadows KL; Ashley AE Examination of factors that influence the expansion of the fragile X mutation in a sample of conceptuses from known carrier females | 13 | 16 |
| 225 | 2 | 21 | 197 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):309-312 Maddalena A; Yadvish KN; Spence WC; HowardPeebles PN A fragile X mosaic male with a cryptic full mutation detected in epithelium but not in blood | 13 | 16 |
| 226 | 2 | 31 | 203 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):350-355 WrightTalamante C; Cheema A; Riddle JE; Luckey DW; Taylor AK; et al. A controlled study of longitudinal IQ changes in females and males with fragile X syndrome | 14 | 16 |
| 227 | 2 | 21 | 206 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):365-369 Cohen IL; Nolin SL; Sudhalter V; Ding XH; Dobkin CS; et al. Mosaicism for the FMR1 gene influences adaptive skills development in fragile X-affected males | 15 | 16 |
| 228 | 0 | 26 | 253 1996 HUMAN GENETICS 97(6):808-812 Haddad LA; MingroniNetto RC; ViannaMorgante AM; Pena SDJ A PCR-based test suitable for screening for fragile X syndrome among mentally retarded males | 9 | 16 |
| 229 | 2 | 13 | 267 1996 JOURNAL OF MEDICAL GENETICS 33(4):338-340 Mila M; CastellviBel S; Sanchez A; Lazaro C; Villa M; et al. Mosaicism for the fragile X syndrome full mutation and deletions within the CGG repeat of the FMR1 gene | 11 | 16 |
| 230 | 1 | 4 | 276 1996 LANCET 348(9032):967-968 Willemsen R; Oosterwijk JC; Los FJ; Galjaard H; Oostra BA Prenatal diagnosis of fragile X syndrome | 11 | 16 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 231 | 6 | 32 | 402 1997 JOURNAL OF MEDICAL GENETICS 34(8):627-631 Kunst CB; Leeflang EP; Iber JC; Arnheim N; Warren ST The effect of FMR1 CGG repeat interruptions on mutation frequency as measured by sperm typing | 3 | 16 |
| 232 | 2 | 33 | 485 1998 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS 15(4):745-756 Chen X; Mariappan SVS; Moyzis RK; Bradbury EM; Gupta G Hairpin induced slippage and hyper-methylation of the fragile X DNA triplets | 4 | 16 |
| 233 | 0 | 40 | 486 1998 JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES 39(5):699-710 van Lieshout CFM; De Meyer RE; Curfs LMG; Fryns JP Family contexts, parental behaviour, and personality profiles of children and adolescents with Prader-Willi, fragile-X, or Williams syndrome | 4 | 16 |
| 234 | 2 | 36 | 508 1998 NEUROPSYCHOLOGIA 36(11):1239-1246 Cornish KM; Munir F; Cross G The nature of the spatial deficit in young females with Fragile-X syndrome: A neuropsychological and molecular perspective | 12 | 16 |
| 235 | 6 | 20 | 551 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 83(4):308-312 Fisch GS; Carpenter N; Holden JJA; Howard-Peebles PN; Maddalena A; et al. Longitudinal changes in cognitive and adaptive behavior in fragile X females: A prospective multicenter analysis | 10 | 16 |
| 236 | 4 | 30 | 598 1999 CORTEX 35(2):263-271 Cornish KM; Munir F; Cross G Spatial cognition in males with Fragile-X syndrome: Evidence for a neuropsychological phenotype | 14 | 16 |
| 237 | 4 | 8 | 657 2000 AMERICAN JOURNAL OF HUMAN GENETICS 67(1):254-255 Vianna-Morgante AM; Costa SS Premature ovarian failure is associated with maternally and paternally inherited premutation in Brazilian families with fragile X | 8 | 16 |
| 238 | 5 | 29 | 750 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(9):6447-6452 Muller-Hartmann H; Deissler H; Naumann F; Schmitz B; Schroer J; et al. The human 20-kDa 5 '-(CGG)(n)-3 '-binding protein is targeted to the nucleus and affects the activity of the FMR1 promoter | 11 | 16 |
| 239 | 8 | 31 | 910 2001 PRENATAL DIAGNOSIS 21(6):504-511 Apessos A; Abou-Sleiman PM; Harper JC; Delhanty JDA Preimplantation genetic diagnosis of the fragile X syndrome by use of linked polymorphic markers | 1 | 16 |
| 240 | 20 | 53 | 1035 2002 MOLECULAR AND CELLULAR BIOLOGY 22(24):8438-8447 Siomi MC; Higashijima K; Ishizuka A; Siomi H Casein kinase II phosphorylates the fragile X mental retardation protein and modulates its biological properties | 14 | 16 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 241 | 0 | 20 | 184 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(1):234-238 Syrrou M; Patsalis PC; Georgiou I; Hadjimarcou MI; ConstantinouDeltas CD; et al. Evidence for high-risk haplotypes and (CGG)n expansion in fragile X syndrome in the Hellenic population of Greece and Cyprus | 9 | 15 |
| 242 | 3 | 29 | 259 1996 HUMAN MOLECULAR GENETICS 5(6):821-825 Mornet E; Chateau C; Hirst MC; Thepot F; Taillandier A; et al. Analysis of germline variation at the FMR1 CGG repeat shows variation in the normal-premutated borderline range | 6 | 15 |
| 243 | 5 | 35 | 293 1996 SOMATIC CELL AND MOLECULAR GENETICS 22(6):435-441 Eberhart DE; Warren ST Nuclease sensitivity of permeabilized cells confirms altered chromatin formation at the fragile X locus | 7 | 15 |
| 244 | 1 | 14 | 364 1997 CLINICAL GENETICS 52(4):211-215 Arvio M; Peippo M; Simola KOJ Applicability of a checklist for clinical screening of the fragile X syndrome | 10 | 15 |
| 245 | 0 | 36 | 480 1998 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 28(6):509-517 Mazzocco MMM; Baumgardner T; Freund LS; Reiss AL Social functioning among girls with fragile X or Turner syndrome and their sisters | 11 | 15 |
| 246 | 7 | 52 | 517 1999 AMERICAN JOURNAL OF HUMAN GENETICS 65(3):680-688 Nolin SL; Houck GE; Gargano AD; Blumstein H; Dobkin CS; et al. FMR1 CCG-repeat instability by single sperm and lymphocytes of fragile-X premutation males | 8 | 15 |
| 247 | 5 | 21 | 724 2000 EUROPEAN JOURNAL OF HUMAN GENETICS 8(4):247-252 Murray A; Ennis S; MacSwiney F; Webb J; Morton NE Reproductive and menstrual history of females with fragile X expansions | 11 | 15 |
| 248 | 4 | 32 | 756 2000 JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS 21(5):315-321 Bailey DB; Skinner D; Hatton D; Roberts J Family experiences and factors associated with the diagnosis of fragile X syndrome | 12 | 15 |
| 249 | 12 | 37 | 838 2001 AMERICAN JOURNAL ON MENTAL RETARDATION 106(1):16-27 Bailey DB; Hatton DD; Tassone F; Skinner M; Taylor AK Variability in FMRP and early development in males with fragile X syndrome | 16 | 15 |
| 250 | 15 | 53 | 847 2001 BRAIN 124:1610-1618 Eliez S; Blasey CM; Freund LS; Hastie T; Reiss AL Brain anatomy, gender and IQ in children and adolescents with fragile X syndrome | 9 | 15 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 251 | 12 | 17 | 853 2001 CELL 107(5):555-557 Kaytor MD; Orr HT RNA targets of the fragile X protein | 6 | 15 |
| 252 | 15 | 45 | 875 2001 HUMAN MOLECULAR GENETICS 10(16):1693-1699 Bontekoe CJM; Bakker CE; Nieuwenhuizen IM; van der Linde H; Lans H; et al. Instability of a (CGG)(98) repeat in the Fmr1 promoter | 12 | 15 |
| 253 | 6 | 71 | 883 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(21):18605-18613 Bacolla A; Pradhan S; Larson JE; Roberts RJ; Wells RD Recombinant human DNA (cytosine-5) methyltransferase - III. Allosteric control, reaction order, and influence of plasmid topology and triplet repeat length on methylation of the fragile X CGG center dot CCG sequence | 0 | 15 |
| 254 | 11 | 46 | 970 2002 BRAIN RESEARCH 927(1):8-17 Nielsen DM; Derber WJ; McClellan DA; Crnic LS Alterations in the auditory startle response in Fmr1 targeted mutant mouse models of fragile X syndrome | 11 | 15 |
| 255 | 21 | 62 | 1133 2003 DEVELOPMENT 130(22):5543-5552 Lee A; Li WJ; Xu KY; Bogert BA; Su K; et al. Control of dendritic development by the Drosophila fragile X-related gene involves the small GTPase Rac1 | 10 | 15 |
| 256 | 17 | 53 | 1149 2003 HUMAN MOLECULAR GENETICS 12(24):3295-3305 Ceman S; O'Donnell WT; Reed M; Patton S; Pohl J; et al. Phosphorylation influences the translation state of FMRP-associated polyribosomes | 12 | 15 |
| 257 | 15 | 55 | 1248 2004 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 291(4):460-469 Jacquemont S; Hagerman RJ; Leehey MA; Hall DA; Levine RA; et al. Penetrance of the fragile X - Associated tremor/ataxia syndrome in a premutation carrier population | 6 | 15 |
| 258 | 12 | 37 | 1276 2004 JOURNAL OF NEUROSCIENCE 24(11):2648-2655 Antar LN; Afroz R; Dictenberg JB; Carroll RC; Bassell GJ Metabotropic glutamate receptor activation regulates Fragile X mental retardation protein and Fmr1 mRNA localization differentially in dendrites and at synapses | 10 | 15 |
| 259 | 1 | 21 | 38 1995 AMERICAN JOURNAL OF HUMAN GENETICS 57(5):991-993 SHERMAN SL THE HIGH PREVALENCE OF FRAGILE-X PREMUTATION CARRIER FEMALES - IS THIS FREQUENCY UNIQUE TO THE FRENCH-CANADIAN POPULATION | 9 | 14 |
| 260 | 0 | 33 | 44 1995 AMERICAN JOURNAL OF MEDICAL GENETICS 58(3):249-256 LOESCH DZ; HUGGINS RM; HOANG NH GROWTH IN STATURE IN FRAGILE-X FAMILIES - A MIXED LONGITUDINAL-STUDY | 12 | 14 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 261 | 2 | 31 | 114 1995 HUMAN MOLECULAR GENETICS 4(9):1681-1684 QUAN F; GROMPE M; JAKOBS P; POPOVICH BW SPONTANEOUS DELETION IN THE FMR1 GENE IN A PATIENT WITH FRAGILE-X SYNDROME AND CHERUBISM | 9 | 14 |
| 262 | 1 | 30 | 440 1998 ARQUIVOS DE NEURO-PSIQUIATRIA 56(1):18-23 Guerreiro MM; Camargo EE; Kato M; Marques-De-Faria AP; Ciasca SM; et al. Fragile X syndrome - Clinical, electroencephalographic and neuroimaging characteristics | 8 | 14 |
| 263 | 2 | 66 | 483 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(41):26998-27008 Parsons MA; Sinden RR; Izban MG Transcriptional properties of RNA polymerase II within triplet repeat-containing DNA from the human myotonic dystrophy and fragile X loci | 0 | 14 |
| 264 | 19 | 55 | 738 2000 HUMAN MOLECULAR GENETICS 9(10):1487-1493 Tamanini F; Kirkpatrick LL; Schonkeren J; van Unen L; Bontekoe C; et al. The fragile X-related proteins FXR1P and FXR2P contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins | 9 | 14 |
| 265 | 3 | 37 | 950 2002 AMERICAN JOURNAL OF HUMAN GENETICS 71(4):923-932 Coffee B; Zhang FP; Ceman S; Warren ST; Reines D Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile X syndrome | 3 | 14 |
| 266 | 8 | 28 | 956 2002 AMERICAN JOURNAL OF MEDICAL GENETICS 111(2):140-146 Irwin SA; Idupulapati M; Gilbert ME; Harris JB; Chakravarti AB; et al. Dendritic spine and dendritic field characteristics of layer V pyramidal neurons in the visual cortex of fragile-X knockout mice | 11 | 14 |
| 267 | 7 | 44 | 1004 2002 HUMAN BRAIN MAPPING 16(4):206-218 Rivera SM; Menon V; White CD; Glaser B; Reiss AL Functional brain activation during arithmetic processing in females with fragile X Syndrome is related to FMRI protein expression | 7 | 14 |
| 268 | 3 | 27 | 1041 2002 NEUROBIOLOGY OF DISEASE 10(3):211-218 D'Agata V; Warren ST; Zhao WQ; Torre ER; Alkon DL; et al. Gene expression profiles in a transgenic animal model of fragile X syndrome | 0 | 14 |
| 269 | 16 | 41 | 1061 2002 RNA-A PUBLICATION OF THE RNA SOCIETY 8(12):1482-1488 Primerano B; Tassone F; Hagerman RJ; Hagerman P; Amaldi F; et al. Reduced FMR1 mRNA translation efficiency in Fragile X patients with premutations | 11 | 14 |
| 270 | 8 | 31 | 1106 2003 ANNALS OF NEUROLOGY 53(5):616-623 Berry-Kravis E; Lewin F; Wuu J; Leehey M; Hagerman R; et al. Tremor and ataxia in fragile X premutation carriers: Blinded videotape study | 11 | 14 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 271 | 35 | 80 | 1197 2004 AMERICAN JOURNAL OF HUMAN GENETICS 74(5):805-816 Hagerman PJ; Hagerman RJ The fragile-X premutation: A maturing perspective | 8 | 14 |
| 272 | 0 | 27 | 40 1995 AMERICAN JOURNAL OF HUMAN GENETICS 57(6):1408-1413 LOESCH DZ; HUGGINS R; PETROVIC V; SLATER H EXPANSION OF THE CGG REPEAT IN FRAGILE-X IN THE FMR1 GENE DEPENDS ON THE SEX OF THE OFFSPRING | 8 | 13 |
| 273 | 0 | 75 | 82 1995 DEVELOPMENTAL BRAIN DYSFUNCTION 8(4-6):252-269 Cohen IL Behavioral profiles of autistic and nonautistic fragile X males | 12 | 13 |
| 274 | 0 | 8 | 96 1995 DEVELOPMENTAL BRAIN DYSFUNCTION 8(4-6):405-407 Holden JJA; Chalifoux M; Wing M; JulienInalsingh C; Lawson JS; et al. Distribution and frequency of FMR1 CGG repeat numbers in the general population | 6 | 13 |
| 275 | 0 | 35 | 136 1995 JOURNAL OF MEDICAL GENETICS 32(12):925-929 KIRCHGESSNER CU; WARREN ST; WILLARD HF X INACTIVATION OF THE FMR1 FRAGILE-X MENTAL-RETARDATION GENE | 5 | 13 |
| 276 | 3 | 43 | 196 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):302-308 deGraaff E; deVries BBA; Willemsen R; vanHemel JO; Mohkamsing S; et al. The fragile X phenotype in a mosaic male with a deletion showing expression of the FMR1 protein in 28% of the cells | 12 | 13 |
| 277 | 0 | 24 | 200 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):329-333 AllinghamHawkins DJ; Brown CA; Babul R; Chitayat D; Krekewich K; et al. Tissue-specific methylation differences and cognitive function in fragile X premutation females | 8 | 13 |
| 278 | 0 | 29 | 338 1997 AMERICAN JOURNAL OF MEDICAL GENETICS 68(1):62-69 McConkieRosell A; Spiridigliozzi GA; Iafolla T; Tarleton J; Lachiewicz AM Carrier testing in the fragile X syndrome: Attitudes and opinions of obligate carriers | 7 | 13 |
| 279 | 2 | 11 | 556 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 83(4):327-328 Braat DDM; Smits APT; Thomas CMG Menstrual disorders and endocrine profiles in fragile X carriers prior to 40 years of age: A pilot study | 10 | 13 |
| 280 | 8 | 65 | 603 1999 DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY 41(9):625-632 Hatton DD; Bailey DB; Hargett-Beck MQ; Skinner M; Clark RD Behavioral style of young boys with fragile X syndrome | 9 | 13 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 281 | 1 | 42 | 684 2000 AMERICAN JOURNAL OF MEDICAL GENETICS 92(4):229-236 Lachiewicz AM; Dawson DV; Spiridigliozzi GA Physical characteristics of young boys with fragile X syndrome: Reasons for difficulties in making a diagnosis in young males | 12 | 13 |
| 282 | 6 | 25 | 877 2001 HUMAN REPRODUCTION 16(3):457-462 Hundscheid RDL; Braat DDM; Kiemeney LALM; Smits APT; Thomas CMG Increased serum FSH in female fragile X premutation carriers with either regular menstrual cycles or on oral contraceptives | 8 | 13 |
| 283 | 3 | 47 | 904 2001 NEUROPSYCHOLOGY 15(2):290-299 Bennetto L; Pennington BF; Porter D; Taylor AK; Hagerman RJ Profile of cognitive functioning in women with the fragile X mutation | 10 | 13 |
| 284 | 26 | 56 | 1154 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(18):15669-15678 Sung YJ; Dolzhanskaya N; Nolin SL; Brown T; Currie JR; et al. The fragile X mental retardation protein FMRP binds elongation factor 1A mRNA and negatively regulates its translation in vivo | 8 | 13 |
| 285 | 21 | 45 | 1190 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(24):14374-14378 Todd PK; Mack KJ; Malter JS The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95 | 8 | 13 |
| 286 | 31 | 60 | 1194 2003 TRENDS IN GENETICS 19(3):148-154 Kooy RF Of mice and the fragile X syndrome | 10 | 13 |
| 287 | 0 | 35 | 89 1995 DEVELOPMENTAL BRAIN DYSFUNCTION 8(4-6):336-344 Hagerman RJ; Riddle JE; Roberts LS; Breese K; Fulton M Survey of the efficacy of clonidine in fragile X syndrome | 12 | 12 |
| 288 | 1 | 13 | 159 1996 AMERICAN JOURNAL OF HUMAN GENETICS 58(3):641-643 Brown WT; Zhong N; Dobkin C Positive fragile X microsatellite associations point to a common mechanism of dynamic mutation evolution | 7 | 12 |
| 289 | 4 | 34 | 255 1996 HUMAN GENETICS 98(4):409-414 Schmucker B; Ballhausen WG; Pfeiffer RA Mosaicism of a microdeletion of 486 bp involving the CGG repeat of the FMR1 gene due to misalignment of GTT tandem repeats at chi-like elements flanking both breakpoints and a full mutation | 5 | 12 |
| 290 | 0 | 14 | 284 1996 PEDIATRIC NEUROLOGY 15(4):358-360 Kluger G; Bohm I; Laub MC; Waldenmaier C Epilepsy and fragile X gene mutations | 6 | 12 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 291 | 1 | 11 | 340 1997 AMERICAN JOURNAL OF MEDICAL GENETICS 69(1):114-116 Martin NG; Healey SC; Pangan TS; Heath AC; Turner G Do mothers of dizygotic twins have earlier menopause? A role for fragile X? | 5 | 12 |
| 292 | 2 | 10 | 399 1997 JOURNAL OF MEDICAL GENETICS 34(3):250-251 Willemsen R; Los F; Mohkamsing S; vandenOuweland A; Deelen W; et al. Rapid antibody test for prenatal diagnosis of fragile X syndrome on amniotic fluid cells: A new appraisal | 10 | 12 |
| 293 | 13 | 67 | 617 1999 HUMAN MOLECULAR GENETICS 8(12):2293-2302 Burman RW; Popovich BW; Jacky PB; Turker MS Fully expanded FMR1 CGG repeats exhibit a length-and differentiation-dependent instability in cell hybrids that is independent of DNA methylation | 9 | 12 |
| 294 | 6 | 22 | 636 1999 JOURNAL OF MEDICAL GENETICS 36(6):467-470 de Vries BBA; Mohkamsing S; van den Ouweland AMW; Mol E; Gelsema K; et al. Screening for the fragile X syndrome among the mentally retarded: a clinical study | 4 | 12 |
| 295 | 10 | 59 | 691 2000 AMERICAN JOURNAL OF MEDICAL GENETICS 95(2):150-156 Backes M; Genc B; Schreck J; Doerfler W; Lehmkuhl G; et al. Cognitive and behavioral profile of fragile X boys: Correlations to molecular data | 8 | 12 |
| 296 | 5 | 43 | 839 2001 AMERICAN JOURNAL ON MENTAL RETARDATION 106(1):28-38 Belser RC; Sudhalter V Conversational characteristics of children with fragile X syndrome: Repetitive speech | 9 | 12 |
| 297 | 3 | 21 | 863 2001 ELECTROPHORESIS 22(6):1188-1193 Sung WC; Lee GB; Tzeng CC; Chen SH Plastic microchip electrophoresis for genetic screening: The analysis of polymerase chain reactions products of fragile X (CGG)n alleles | 0 | 12 |
| 298 | 18 | 33 | 1192 2003 RNA-A PUBLICATION OF THE RNA SOCIETY 9(10):1198-1207 Ramos A; Hollingworth D; Pastore A G-quartet-dependent recognition between the FMRP RGG box and RNA | 7 | 12 |
| 299 | 0 | 27 | 133 1995 JOURNAL OF MEDICAL GENETICS 32(3):236-239 MACPHERSON JN; CURTIS G; CROLLA JA; DENNIS N; MIGEON B; et al. UNUSUAL (CGG)(N) EXPANSION AND RECOMBINATION IN A FAMILY WITH FRAGILE-X AND DIGEORGE-SYNDROME | 5 | 11 |
| 300 | 2 | 117 | 150 1995 PEDIATRIC RESEARCH 38(5):629-637 OOSTRA BA; HALLEY DJJ COMPLEX BEHAVIOR OF SIMPLE REPEATS - THE FRAGILE-X SYNDROME | 8 | 11 |