| Missing Links? Citation Matrix | Graphs | Glossary HistCite Guide About |
Nodes: 1364,
Authors: 3358,
Journals: 307,
Outer References: 11901,
Words: 2507
Collection span: 1995 - 2005
View: Overview. Sorted by NCR.
Page 1: 1 2 3 4 5
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 1 | 83 | 233 | 1134 2003 DEVELOPMENT AND PSYCHOPATHOLOGY 15(4):927-968 Reiss AL; Dant CC The behavioral neurogenetics of fragile X syndrome: Analyzing gene-brain-behavior relationships in child developmental psychopathologies | 0 | 0 |
| 2 | 46 | 197 | 496 1998 JOURNAL OF MEDICAL GENETICS 35(7):579-589 de Vries BBA; Halley DJJ; Oostra BA; Niermeijer MF The fragile X syndrome | 32 | 52 |
| 3 | 55 | 179 | 965 2002 ANNUAL REVIEW OF NEUROSCIENCE 25:315-338 O'Donnell WT; Warren ST A decade of molecular studies of fragile X syndrome | 0 | 63 |
| 4 | 59 | 168 | 1130 2003 CYTOGENETIC AND GENOME RESEARCH 100(1-4):111-123 Bakker CE; Oostra BA Understanding fragile X syndrome: insights from animal models | 4 | 5 |
| 5 | 82 | 154 | 870 2001 GENETICS IN MEDICINE 3(5):359-371 Crawford DC; Acuna JM; Sherman SL FMR1 and the fragile X syndrome: Human genome epidemiology review | 17 | 25 |
| 6 | 18 | 143 | 515 1998 ZHURNAL NEVROPATOLOGII I PSIKHIATRII IMENI S S KORSAKOVA 98(9):54-63 Vorsanova SG; Vekhova NV; Demidova IA; Yurov YB Syndrome of mental retardation, linked with fragile X-chromosome: problems of diagnostics and inheritance | 0 | 0 |
| 7 | 33 | 139 | 979 2002 DEVELOPMENTAL PSYCHOBIOLOGY 40(3):323-338 Churchill JD; Grossman AW; Irwin SA; Galvez R; Klintsova AY; et al. A converging-methods approach to fragile X syndrome | 2 | 8 |
| 8 | 0 | 138 | 278 1996 MEDICAL HYPOTHESES 47(4):289-298 Fischer KM Genes for Prader Willi Syndrome Angelman syndrome and fragile X syndrome are homologous, with genetic imprinting and unstable trinucleotide repeats causing mental retardation, autism and aggression | 1 | 4 |
| 9 | 16 | 136 | 586 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 88(1):11-24 Kaufmann WE; Reiss AL Molecular and cellular genetics of fragile X syndrome | 16 | 28 |
| 10 | 36 | 136 | 1129 2003 CYTOGENETIC AND GENOME RESEARCH 100(1-4):65-76 Greene E; Handa V; Kumari D; Usdin K Transcription defects induced by repeat expansion: fragile X syndrome, FRAXE mental retardation, progressive myoclonus epilepsy type 1, and Friedreich ataxia | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 11 | 51 | 135 | 1223 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61(14):1714-1728 Denman RB; Dolzhanskaya N; Sung YJ Regulating a translational regulator: mechanisms cells use to control the activity of the fragile X mental retardation protein | 1 | 2 |
| 12 | 7 | 134 | 387 1997 INTERNATIONAL REVIEW OF RESEARCH IN MENTAL RETARDATION, VOL 21 21:221-247 Fisch GS Longitudinal assessment of cognitive-behavioral deficits produced by the fragile-X mutation | 0 | 1 |
| 13 | 0 | 131 | 77 1995 DEVELOPMENTAL BRAIN DYSFUNCTION 8(4-6):199-217 Binstock TC Fragile X and the amygdala: Cognitive, interpersonal, emotional, and neuroendocrine considerations | 4 | 4 |
| 14 | 0 | 125 | 52 1995 ANNUAL REVIEW OF NEUROSCIENCE 18:77-99 WARREN ST; ASHLEY CT TRIPLET REPEAT EXPANSION MUTATIONS - THE EXAMPLE OF FRAGILE-X SYNDROME | 26 | 58 |
| 15 | 24 | 123 | 427 1997 WESTERN JOURNAL OF MEDICINE 166(2):129-137 Hagerman RJ Fragile X syndrome - Molecular and clinical insights and treatment issues | 6 | 8 |
| 16 | 25 | 120 | 1224 2004 CNS DRUGS 18(11):687-703 Tsiouris JA; Brown WT Neuropsychiatric symptoms of fragile X syndrome - Pathophysiology and pharmacotherapy | 0 | 0 |
| 17 | 29 | 118 | 1152 2003 INTERNATIONAL REVIEW OF RESEARCH IN MENTAL RETARDATION, VOL 27 27:83-119 Murphy MM; Abbeduto L Language and communication in fragile X syndrome | 0 | 0 |
| 18 | 2 | 117 | 150 1995 PEDIATRIC RESEARCH 38(5):629-637 OOSTRA BA; HALLEY DJJ COMPLEX BEHAVIOR OF SIMPLE REPEATS - THE FRAGILE-X SYNDROME | 8 | 11 |
| 19 | 34 | 117 | 790 2000 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 6(2):96-106 Mazzocco MMM Advances in research on the fragile X syndrome | 20 | 24 |
| 20 | 54 | 116 | 695 2000 AMERICAN JOURNAL OF MEDICAL GENETICS 97(2):153-163 Bardoni B; Mandel JL; Fisch GS FMR1 gene and fragile X syndrome | 12 | 21 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 21 | 29 | 114 | 1236 2004 GENES BRAIN AND BEHAVIOR 3(6):337-359 Yan QJ; Asafo-Adjei PK; Arnold HM; Brown RE; Bauchwitz RP A phenotypic and molecular characterization of the fmr1-tm1Cgr Fragile X mouse | 1 | 1 |
| 22 | 3 | 113 | 642 1999 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 5(4):305-313 Hagerman RJ Psychopharmacological interventions in fragile X syndrome, fetal alcohol syndrome, Prader-Willi syndrome, Angelman syndrome, Smith-Magenis syndrome, and velocardiofacial syndrome | 0 | 2 |
| 23 | 0 | 112 | 59 1995 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1271(2-3):293-303 FLANNERY AV; HIRST MC; KNIGHT SJL; RITCHIE RJ; DAVIES KE THE FRAGILE-X SYNDROME | 2 | 5 |
| 24 | 43 | 108 | 900 2001 MOLECULAR GENETICS AND METABOLISM 74(1-2):89-97 Hagerman RJ; Hagerman PJ Fragile X syndrome: A model of gene-brain-behavior relationships | 1 | 2 |
| 25 | 17 | 107 | 448 1998 CURRENT OPINION IN GENETICS & DEVELOPMENT 8(2):245-253 Tapscott SJ; Klesert TR; Widrow RJ; Stoger R; Laird CD Fragile-X syndrome and myotonic dystrophy: parallels and paradoxes | 1 | 10 |
| 26 | 41 | 105 | 922 2001 REVISTA DE NEUROLOGIA 33:S51-S57 Hagerman RJ; Hagerman PJ Fragile X syndrome: A model of gene-brain-behaviour relationships | 0 | 0 |
| 27 | 4 | 104 | 478 1998 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 28(5):393-405 Feinstein C; Reiss AL Autism: The point of view from fragile X studies | 18 | 45 |
| 28 | 40 | 103 | 1253 2004 JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY 45(6):1042-1053 Cornish KM; Turk J; Wilding J; Sudhalter V; Munir F; et al. Annotation: Deconstructing the attention deficit in fragile X syndrome: a developmental neuropsychological approach | 0 | 0 |
| 29 | 33 | 102 | 932 2001 SEMINARS IN REPRODUCTIVE MEDICINE 19(2):159-165 Kenneson A; Warren ST The female and the fragile X reviewed | 1 | 3 |
| 30 | 35 | 102 | 1292 2004 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 10(1):60-67 Willemsen R; Oostra BA; Bassell GJ; Dictenberg J The fragile X syndrome: From molecular genetics to neurobiology | 2 | 5 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 31 | 17 | 101 | 1182 2003 NEUROPSYCHOLOGY 17(4):646-657 Loesch DZ; Bui QM; Grigsby J; Butler E; Epstein J; et al. Effect of the fragile X status categories and the fragile X mental retardation protein levels on executive functioning in males and females with fragile X | 1 | 1 |
| 32 | 29 | 101 | 1316 2004 NEUROPSYCHOLOGIA 42(14):1934-1947 Moore CJ; Daly EM; Schmitz N; Tassone F; Tysoe C; et al. A neuropsychological investigation of male premutation carriers of fragile X syndrome | 0 | 0 |
| 33 | 45 | 100 | 856 2001 CLINICAL GENETICS 60(6):399-408 Oostra BA; Chiurazzi P The fragile X gene and its function | 5 | 11 |
| 34 | 26 | 98 | 593 1999 BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE 77(4):331-342 Khandjian EW Biology of the fragile X mental retardation protein, an RNA-binding protein | 14 | 22 |
| 35 | 53 | 98 | 1021 2002 JOURNAL OF NEUROSCIENCE RESEARCH 70(5):623-630 Todd PK; Malter JS Fragile X mental retardation protein in plasticity and disease | 1 | 4 |
| 36 | 9 | 98 | 1341 2005 APPLIED PSYCHOLINGUISTICS 26(1):7-27 Rice ML; Warren SF; Betz SK Language symptoms of developmental language disorders: An overview of autism, Down syndrome, fragile X, specific language impairment, and Williams syndrome | 0 | 1 |
| 37 | 36 | 97 | 1277 2004 JOURNAL OF NEUROSCIENCE 24(25):5798-5809 Michel CI; Kraft R; Restifo LL Defective neuronal development in the mushroom bodies of Drosophila Fragile X Mental Retardation 1 Mutants | 6 | 7 |
| 38 | 26 | 96 | 623 1999 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 3(6):639-645 Pimentel MMG Fragile X syndrome | 0 | 5 |
| 39 | 11 | 95 | 234 1996 CHILD AND ADOLESCENT PSYCHIATRIC CLINICS OF NORTH AMERICA 5(4):895-& Hagerman RJ Fragile X syndrome | 1 | 9 |
| 40 | 30 | 95 | 1336 2004 TRENDS IN NEUROSCIENCES 27(7):370-377 Bear MF; Huber KM; Warren ST The mGIuR theory of fragile X mental retardation | 8 | 10 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 41 | 1 | 94 | 243 1996 DEVELOPMENTAL PSYCHOLOGY 32(3):416-424 Hagerman RJ Biomedical advances in developmental psychology: The case of fragile X syndrome | 3 | 8 |
| 42 | 36 | 94 | 859 2001 CURRENT OPINION IN PSYCHIATRY 14(5):443-449 Eliez S; Feinstein C The fragile X syndrome: bridging the gap from gene to behavior | 0 | 1 |
| 43 | 56 | 93 | 976 2002 CURRENT OPINION IN GENETICS & DEVELOPMENT 12(3):284-293 Bardoni B; Mandel JL Advances in understanding of fragile X pathogenesis and FMRP function, and in identification of X linked mental retardation genes | 31 | 39 |
| 44 | 0 | 92 | 49 1995 AMERICAN JOURNAL OF MEDICAL GENETICS 60(6):480-493 Schapiro MB; Murphy DGM; Hagerman RJ; Azari NP; Alexander GE; et al. Adult fragile X syndrome: Neuropsychology, brain anatomy, and metabolism | 21 | 31 |
| 45 | 12 | 92 | 409 1997 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 3(4):313-322 Abbeduto L; Hagerman RJ Language and communication in fragile X syndrome | 10 | 17 |
| 46 | 5 | 91 | 890 2001 JOURNAL OF LEARNING DISABILITIES 34(6):520-533 Mazzocco MMM Math learning disability and math LD subtypes: Evidence from studies of Turner syndrome, fragile X syndrome, and neurofibromatosis type 1 | 2 | 8 |
| 47 | 1 | 88 | 503 1998 MEDICAL HYPOTHESES 51(3):223-233 Fischer KM Expanded (CAG)(n), (CGG)(n) and (GAA)(n) trinucleotide repeat microsatellites, and mutant purine synthesis and pigmentation genes cause schizophrenia and autism | 0 | 2 |
| 48 | 23 | 88 | 848 2001 BRAIN RESEARCH BULLETIN 56(3-4):367-373 Grabczyk E; Kumari D; Usdin K Fragile X syndrome and Friedreich's ataxia: Two different paradigms for repeat induced transcript insufficiency | 0 | 4 |
| 49 | 68 | 87 | 1128 2003 CURRENT OPINION IN PEDIATRICS 15(6):559-566 Chiurazzi P; Neri G; Oostra BA Understanding the biological underpinnings of fragile X syndrome | 2 | 5 |
| 50 | 11 | 86 | 861 2001 DEVELOPMENTAL PSYCHOBIOLOGY 39(2):107-123 Roberts JE; Boccia ML; Bailey DB; Hatton DD; Skinner M Cardiovascular indices of physiological arousal in boys with fragile X syndrome | 7 | 7 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 51 | 34 | 85 | 849 2001 BRAIN RESEARCH BULLETIN 56(3-4):375-382 Bardoni B; Schenck A; Mandel JL The Fragile X mental retardation protein | 6 | 9 |
| 52 | 11 | 85 | 852 2001 CELL 107(4):489-499 Darnell JC; Jensen KB; Jin P; Brown V; Warren ST; et al. Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function | 74 | 149 |
| 53 | 47 | 84 | 977 2002 CYTOGENETIC AND GENOME RESEARCH 99(1-4):257-264 Oostra BA; Willemsen R The X chromosome and fragile X mental retardation | 2 | 3 |
| 54 | 32 | 82 | 737 2000 HUMAN MOLECULAR GENETICS 9(6):901-908 Jin P; Warren ST Understanding the molecular basis of fragile X syndrome | 44 | 82 |
| 55 | 41 | 82 | 1026 2002 MICROSCOPY RESEARCH AND TECHNIQUE 57(3):135-144 Kaufmann WE; Cohen S; Sun HT; Ho G Molecular phenotype of fragile X syndrome: FMRP, FXRPs, and protein targets | 1 | 1 |
| 56 | 18 | 82 | 1293 2004 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 10(1):68-74 Siomi H; Ishizuka A; Siomi MC RNA interference: A new mechanism by which FMRP acts in the normal brain? What can drosophila teach us? | 1 | 4 |
| 57 | 2 | 81 | 228 1996 BIOCHEMISTRY 35(15):5041-5053 Pearson CE; Sinden RR Alternative structures in duplex DNA formed within the trinucleotide repeats of the myotonic dystrophy and fragile X loci | 4 | 91 |
| 58 | 11 | 80 | 1053 2002 OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA 29(2):367-+ Wenstrom KD Fragile X and other trinucleotide repeat diseases | 1 | 3 |
| 59 | 35 | 80 | 1197 2004 AMERICAN JOURNAL OF HUMAN GENETICS 74(5):805-816 Hagerman PJ; Hagerman RJ The fragile-X premutation: A maturing perspective | 8 | 14 |
| 60 | 17 | 79 | 712 2000 CEREBRAL CORTEX 10(10):1038-1044 Irwin SA; Galvez R; Greenough WT Dendritic spine structural anomalies in fragile-X mental retardation syndrome | 35 | 55 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 61 | 13 | 79 | 999 2002 GENES & DEVELOPMENT 16(19):2497-2508 Ishizuka A; Siomi MC; Siomi H A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins | 27 | 91 |
| 62 | 13 | 79 | 1213 2004 AMERICAN JOURNAL ON MENTAL RETARDATION 109(3):237-254 Abbeduto L; Seltzer MM; Shattuck P; Krauss MW; Orsmond G; et al. Psychological well-being and coping in mothers of youths with autism, Down syndrome, or fragile X syndrome | 0 | 1 |
| 63 | 2 | 78 | 72 1995 CLINICS IN LABORATORY MEDICINE 15(4):859-& Brown WT Perspectives and molecular diagnosis of the fragile X syndrome | 2 | 2 |
| 64 | 1 | 77 | 292 1996 SCREENING 4(4):175-192 Meadows KL; Sherman SL Fragile X syndrome: Examination of issues pertaining to population-based screening | 2 | 2 |
| 65 | 54 | 77 | 1364 2005 TRENDS IN GENETICS 21(1):37-45 Zhang YQ; Broadie K Fathoming fragile X in fruit flies | 1 | 1 |
| 66 | 1 | 75 | 76 1995 DEVELOPMENTAL BRAIN DYSFUNCTION 8(4-6):187-198 Abrams MT; Reiss AL Quantitative brain imaging studies of fragile X syndrome | 2 | 3 |
| 67 | 0 | 75 | 82 1995 DEVELOPMENTAL BRAIN DYSFUNCTION 8(4-6):252-269 Cohen IL Behavioral profiles of autistic and nonautistic fragile X males | 12 | 13 |
| 68 | 16 | 75 | 487 1998 JOURNAL OF CLINICAL LIGAND ASSAY 21(4):424-431 Feldman GL; Monaghan KG Fragile X syndrome: A review of the molecular and clinical features | 0 | 0 |
| 69 | 19 | 75 | 1036 2002 MOLECULAR AND CELLULAR NEUROSCIENCE 19(2):138-151 Li JX; Pelletier MR; Velazquez JLP; Carlen PL Reduced cortical synaptic plasticity and GluR1 expression associated with fragile X mental retardation protein deficiency | 18 | 20 |
| 70 | 22 | 75 | 1315 2004 NEUROLOGY INDIA 52(1):36-42 Pandey UB; Phadke SR; Mittal B Molecular diagnosis and genetic counseling for fragile X mental retardation | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 71 | 9 | 74 | 240 1996 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 61:679-687 Eberhart DE; Warren ST The molecular basis of fragile X syndrome | 7 | 8 |
| 72 | 11 | 74 | 643 1999 MOLECULAR AND CELLULAR BIOLOGY 19(8):5675-5684 White PJ; Borts RH; Hirst MC Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism | 12 | 45 |
| 73 | 14 | 74 | 791 2000 MOLECULAR AND CELLULAR BIOLOGY 20(22):8536-8547 Wan LL; Dockendorff TC; Jongens TA; Dreyfuss G Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein | 44 | 57 |
| 74 | 24 | 74 | 1286 2004 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 10(1):17-24 Hessl D; Rivera SM; Reiss AL The neuroanatomy and neuroendocrinotogy of fragile X syndrome | 1 | 2 |
| 75 | 9 | 73 | 857 2001 COGNITIVE NEUROPSYCHOLOGY 18(1):1-18 Simon JA; Keenan JM; Pennington BF; Taylor AK; Hagerman RJ Discourse processing in women with fragile X syndrome: Evidence for a deficit establishing coherence | 8 | 10 |
| 76 | 41 | 73 | 1307 2004 NATURE CELL BIOLOGY 6(11):1048-1053 Jin P; Alisch RS; Warren ST RNA and microRNAs in fragile X mental retardation | 2 | 3 |
| 77 | 0 | 71 | 247 1996 EUROPEAN PSYCHIATRY 11(5):233-243 Franke P; Barbe B; Leboyer M; Maier W Fragile X syndrome .2. Cognitive and behavioral correlates of mutations of the FMR-1 gene | 5 | 6 |
| 78 | 6 | 71 | 883 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(21):18605-18613 Bacolla A; Pradhan S; Larson JE; Roberts RJ; Wells RD Recombinant human DNA (cytosine-5) methyltransferase - III. Allosteric control, reaction order, and influence of plasmid topology and triplet repeat length on methylation of the fragile X CGG center dot CCG sequence | 0 | 15 |
| 79 | 0 | 70 | 156 1995 SEMINARS IN CELL BIOLOGY 6(1):5-11 NELSON DL THE FRAGILE-X SYNDROMES | 4 | 16 |
| 80 | 9 | 69 | 420 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(9):4587-4592 Hansen RS; Canfield TK; Fjeld AD; Mumm S; Laird CD; et al. A variable domain of delayed replication in FRAXA fragile X chromosomes: X inactivation-like spread of late replication | 8 | 41 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 81 | 14 | 69 | 1172 2003 LANGUAGE SPEECH AND HEARING SERVICES IN SCHOOLS 34(4):320-331 Mirrett PL; Roberts JE Early intervention practices and communication intervention strategies for young males with fragile X syndrome | 0 | 0 |
| 82 | 19 | 68 | 1351 2005 HUMAN MOLECULAR GENETICS 14(6):835-844 Castets M; Schaeffer C; Bechara E; Schenck A; Khandjian EW; et al. FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts | 0 | 0 |
| 83 | 2 | 67 | 137 1995 JOURNAL OF MOLECULAR BIOLOGY 254(4):638-656 KETTANI A; KUMAR RA; PATEL DJ SOLUTION STRUCTURE OF A DNA QUADRUPLEX CONTAINING THE FRAGILE-X SYNDROME TRIPLET REPEAT | 15 | 98 |
| 84 | 13 | 67 | 617 1999 HUMAN MOLECULAR GENETICS 8(12):2293-2302 Burman RW; Popovich BW; Jacky PB; Turker MS Fully expanded FMR1 CGG repeats exhibit a length-and differentiation-dependent instability in cell hybrids that is independent of DNA methylation | 9 | 12 |
| 85 | 18 | 67 | 1285 2004 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 10(1):11-16 Cornish K; Sudhalter V; Turk J Attention and language in fragile X | 1 | 1 |
| 86 | 2 | 66 | 483 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(41):26998-27008 Parsons MA; Sinden RR; Izban MG Transcriptional properties of RNA polymerase II within triplet repeat-containing DNA from the human myotonic dystrophy and fragile X loci | 0 | 14 |
| 87 | 20 | 66 | 781 2000 JOURNAL OF MEDICAL GENETICS 37(11):842-850 Salat U; Bardoni B; Wohrle D; Steinbach P Increase of FMRP expression, raised levels of FMR1 mRNA, and clonal selection in proliferating cells with unmethylated fragile X repeat expansions: a clue to the sex bias in the transmission of full mutations? | 4 | 6 |
| 88 | 8 | 66 | 1037 2002 MONATSSCHRIFT KINDERHEILKUNDE 150(12):1486-+ Backes M; von Gontard A Behavioural phenotype of fragile X syndrome | 0 | 0 |
| 89 | 29 | 66 | 1288 2004 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 10(1):31-41 Loesch DZ; Huggins RM; Hagerman RJ Phenotypic variation and FMRP levels in fragile X | 1 | 1 |
| 90 | 7 | 66 | 1294 2004 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 10(1):75-81 Rattazzi MC; LaFauci G; Brown WT Prospects for gene therapy in the fragile X syndrome | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 91 | 0 | 65 | 3 1995 AMERICAN JOURNAL OF HUMAN GENETICS 56(5):1147-1155 FISCH GS; SNOW K; THIBODEAU SN; CHALIFAUX M; HOLDEN JJA; et al. THE FRAGILE-X PREMUTATION IN CARRIERS AND ITS EFFECT ON MUTATION SIZE IN OFFSPRING | 28 | 35 |
| 92 | 8 | 65 | 603 1999 DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY 41(9):625-632 Hatton DD; Bailey DB; Hargett-Beck MQ; Skinner M; Clark RD Behavioral style of young boys with fragile X syndrome | 9 | 13 |
| 93 | 33 | 65 | 1272 2004 JOURNAL OF MOLECULAR BIOLOGY 343(1):43-53 Menon RP; Gibson TJ; Pastore A The C terminus of fragile X mental retardation protein interacts with the multi-domain ran-binding protein in the microtubule-organising centre | 0 | 0 |
| 94 | 34 | 64 | 365 1997 CURRENT OPINION IN NEUROLOGY 10(2):142-147 Chakrabarti L; Davies KE Fragile X syndrome | 2 | 4 |
| 95 | 2 | 64 | 378 1997 HUMAN GENETICS 100(3-4):407-414 Lavedan CN; Garrett L; Nussbaum RL Trinucleotide repeats (CGG)(22)TGG(CGG)(43)TGG(CGG)(21) from the fragile X gene remain stable in transgenic mice | 14 | 19 |
| 96 | 2 | 64 | 385 1997 HUMAN MOLECULAR GENETICS 6(11):1791-1801 Stoger R; Kajimura TM; Brown WT; Laird CD Epigenetic variation illustrated by DNA methylation patterns of the fragile-X gene FMR1 | 12 | 38 |
| 97 | 24 | 64 | 575 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 84(3):250-261 Tassone F; Hagerman RJ; Ikle DN; Dyer PN; Lampe M; et al. FMRP expression as a potential prognostic indicator in fragile X syndrome | 60 | 67 |
| 98 | 20 | 64 | 876 2001 HUMAN MOLECULAR GENETICS 10(24):2803-2811 Huot ME; Mazroui R; Leclerc P; Khandjian EW Developmental expression of the fragile X-related 1 proteins in mouse testis: association with microtubule elements | 5 | 7 |
| 99 | 33 | 64 | 1028 2002 MICROSCOPY RESEARCH AND TECHNIQUE 57(3):148-155 Hoogeveen AT; Willemsen R; Oostra BA Fragile X syndrome, the fragile X related proteins, and animal models | 1 | 4 |
| 100 | 21 | 64 | 1180 2003 NEURON 38(6):887-898 Schenck A; Bardoni B; Langmann C; Harden N; Mandel JL; et al. CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein | 11 | 23 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 101 | 10 | 63 | 288 1996 PRENATAL DIAGNOSIS 16(13):1199-1211 Sutherland GR; Mulley JC Fragile X syndrome and Fragile XE mental retardation | 3 | 9 |
| 102 | 2 | 63 | 506 1998 NEUROLOGY 50(1):121-130 Mostofsky SH; Mazzocco MMM; Aakalu G; Warsofsky IS; Denckla MB; et al. Decreased cerebellar posterior vermis size in fragile X syndrome - Correlation with neurocognitive performance | 21 | 48 |
| 103 | 0 | 62 | 251 1996 GIORNALE DI NEUROPSICHIATRIA DELL ETA EVOLUTIVA 16(2):147-154 Veneselli E; Biancheri R; Perrone MV Neuropsychiatric aspects in the fragile X syndrome | 0 | 0 |
| 104 | 7 | 62 | 463 1998 GENOMICS 50(2):229-240 Lavedan C; Grabczyk E; Usdin K; Nussbaum RL Long uninterrupted CGG repeats within the first exon of the human FMR1 gene are not intrinsically unstable in transgenic mice | 17 | 21 |
| 105 | 8 | 62 | 736 2000 HUMAN MOLECULAR GENETICS 9(1):93-100 Balakumaran BS; Freudenreich CH; Zakian VA CGG/CCG repeats exhibit orientation-dependent instability and orientation-independent fragility in Saccharomyces cerevisiae | 0 | 20 |
| 106 | 27 | 62 | 739 2000 HUMAN MOLECULAR GENETICS 9(12):1759-1769 Crawford DC; Zhang FP; Wilson B; Warren ST; Sherman SL Fragile X CGG repeat structures among African-Americans: identification of a novel factor responsible for repeat instability | 7 | 11 |
| 107 | 18 | 62 | 850 2001 BRAIN RESEARCH BULLETIN 56(3-4):383-387 Chiurazzi P; Neri G Pharmacological reactivation of inactive genes: The fragile X experience | 0 | 1 |
| 108 | 17 | 62 | 864 2001 EMBO JOURNAL 20(17):4803-4813 Schaeffer C; Bardoni B; Mandel JL; Ehresmann B; Ehresmann C; et al. The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif | 66 | 97 |
| 109 | 12 | 62 | 953 2002 AMERICAN JOURNAL OF MEDICAL GENETICS 108(2):105-116 Hatton DD; Hooper SR; Bailey DB; Skinner ML; Sullivan KM; et al. Problem behavior in boys with fragile X syndrome | 6 | 7 |
| 110 | 18 | 62 | 1097 2003 AMERICAN JOURNAL OF MEDICAL GENETICS PART A 122A(1):13-23 Loesch DZ; Huggins RM; Bui QM; Taylor AK; Pratt C; et al. Effect of fragile x status categories and FMRP deficits on cognitive profiles estimated by robust pedigree analysis | 0 | 5 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 111 | 19 | 62 | 1121 2003 BMC MOLECULAR BIOLOGY 4 Chandler SP; Kansagra P; Hirst MC Fragile X (CGG)(n) repeats induce a transcriptional repression in cis upon a linked promoter: Evidence for a chromatin mediated effect | 0 | 3 |
| 112 | 27 | 62 | 1125 2003 CELL 112(3):317-327 Zalfa F; Giorgi M; Primerano B; Moro A; Di Penta A; et al. The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at Synapses | 37 | 69 |
| 113 | 21 | 62 | 1133 2003 DEVELOPMENT 130(22):5543-5552 Lee A; Li WJ; Xu KY; Bogert BA; Su K; et al. Control of dendritic development by the Drosophila fragile X-related gene involves the small GTPase Rac1 | 10 | 15 |
| 114 | 21 | 62 | 1218 2004 BRAIN 127:591-601 Kogan CS; Boutet I; Cornish K; Zangenehpour S; Mullen KT; et al. Differential impact of the FMR1 gene on visual processing in fragile X syndrome | 2 | 2 |
| 115 | 0 | 61 | 144 1995 NEUROPSYCHOLOGY 9(4):470-480 MAZZOCCO MMM; FREUND LS; BAUMGARDNER TL; FORMAN L; REISS AL NEUROPSYCHOLOGICAL AND PSYCHOSOCIAL EFFECTS OF THE FMR-1 FULL MUTATION - CASE-REPORT OF MONOZYGOTIC TWINS DISCORDANT FOR THE FRAGILE-X SYNDROME | 5 | 6 |
| 116 | 3 | 61 | 388 1997 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 27(4):415-435 Mazzocco MMM; Kates WR; Baumgardner TL; Freund LS; Reiss AL Autistic behaviors among girls with fragile X syndrome | 20 | 25 |
| 117 | 18 | 61 | 541 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 83(4):221-236 Holden JJA; Percy M; Allingham-Hawkins D; Brown WT; Chiurazzi P; et al. Eighth International Workshop on the Fragile X Syndrome and X-linked Mental Retardation, August 16-22, 1997 | 1 | 4 |
| 118 | 2 | 61 | 1014 2002 JOURNAL OF COGNITIVE NEUROSCIENCE 14(2):160-171 Tamm L; Menon V; Johnston CK; Hessl DR; Reiss AL fMRI study of cognitive interference processing in females with fragile X syndrome | 6 | 10 |
| 119 | 26 | 61 | 1137 2003 EXPERIMENTAL CELL RESEARCH 289(1):95-107 Bardoni B; Willemsen R; Weiler IJ; Schenck A; Severijnen LA; et al. NUFIP 1 (nuclear FMRP interacting protein 1) is a nucleocytoplasmic shuttling protein associated with active synaptoneurosome | 6 | 7 |
| 120 | 20 | 61 | 1173 2003 MOLECULAR BRAIN RESEARCH 110(2):267-278 Todd PK; Malter JS; Mack KJ Whisker stimulation-dependent translation of FMRP in the barrel cortex requires activation of type I metabotropic glutamate receptors | 4 | 3 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 121 | 24 | 61 | 1327 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(36):13357-13362 Khandjian EW; Huot ME; Tremblay S; Davidovic L; Mazroui R; et al. Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles | 6 | 7 |
| 122 | 17 | 61 | 1330 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(50):17428-17433 Ling SC; Fahrner PS; Greenough WT; Gelfand VI Transport of Drosophila fragile X rental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein | 0 | 1 |
| 123 | 24 | 61 | 1358 2005 MOLECULAR & CELLULAR PROTEOMICS 4(3):278-290 Zhang YQ; Friedman DB; Wang Z; Woodruff E; Pan LY; et al. Protein expression profiling of the Drosophila fragile X mutant brain reveals up-regulation of monoamine synthesis | 0 | 0 |
| 124 | 3 | 60 | 390 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272(27):16783-16792 Bacolla A; Gellibolian R; Shimizu M; Amirhaeri S; Kang S; et al. Flexible DNA: Genetically unstable CTG center dot CAG and CGG center dot CCG from human hereditary neuromuscular disease genes | 3 | 57 |
| 125 | 9 | 60 | 1103 2003 AMERICAN JOURNAL ON MENTAL RETARDATION 108(5):314-326 Demark JL; Feldman MA; Holden JJA Behavioral relationship between autism and fragile X syndrome | 1 | 2 |
| 126 | 31 | 60 | 1194 2003 TRENDS IN GENETICS 19(3):148-154 Kooy RF Of mice and the fragile X syndrome | 10 | 13 |
| 127 | 0 | 59 | 140 1995 MEDICINA-BUENOS AIRES 55(5):457-466 BANARES VG UPDATING THE FRAGILE-X SYNDROME | 0 | 0 |
| 128 | 3 | 59 | 181 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(1):209-215 Chiurazzi P; Genuardi M; Kozak L; GiovannucciUzielli ML; Bussani C; et al. Fragile X founder chromosomes in Italy: A few initial events and possible explanation for their heterogeneity | 17 | 26 |
| 129 | 8 | 59 | 406 1997 JOURNAL OF NEUROSCIENCE 17(5):1539-1547 Feng Y; Gutekunst CA; Eberhart DE; Yi H; Warren ST; et al. Fragile X mental retardation protein: Nucleocytoplasmic shuttling and association with somatodendritic ribosomes | 85 | 145 |
| 130 | 10 | 59 | 691 2000 AMERICAN JOURNAL OF MEDICAL GENETICS 95(2):150-156 Backes M; Genc B; Schreck J; Doerfler W; Lehmkuhl G; et al. Cognitive and behavioral profile of fragile X boys: Correlations to molecular data | 8 | 12 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 131 | 4 | 59 | 711 2000 CELL 100(3):323-332 Lewis HA; Musunuru K; Jensen KB; Edo C; Chen H; et al. Sequence-specific RNA binding by a Nova KH domain: Implications for paraneoplastic disease and the fragile X syndrome | 9 | 97 |
| 132 | 15 | 59 | 751 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(42):33134-33141 Uliel L; Weisman-Shomer P; Oren-Jazans H; Newcomb T; Loeb LA; et al. Human Ku antigen tightly binds and stabilizes a tetrahelical form of the fragile X syndrome d(CGG)(n) expanded sequence | 1 | 7 |
| 133 | 20 | 59 | 1043 2002 NEUROBIOLOGY OF DISEASE 11(1):221-229 Castren M; Lampinen KE; Miettinen R; Koponen E; Sipola I; et al. BDNF regulates the expression of fragile X mental retardation protein mRNA in the hippocampus | 2 | 4 |
| 134 | 11 | 59 | 1131 2003 CYTOGENETIC AND GENOME RESEARCH 100(1-4):140-146 Fleming K; Riser DK; Kumari D; Usdin K Instability of the fragile X syndrome repeat in mice: the effect of age, diet and mutations in genes that affect DNA replication, recombination and repair proficiency | 0 | 0 |
| 135 | 15 | 59 | 1209 2004 AMERICAN JOURNAL OF MEDICAL GENETICS PART A 129A(3):225-234 Kaufmann WE; Cortell R; Kau CSM; Bukelis I; Tierney E; et al. Autism spectrum disorder in fragile X syndrome: Communication, social interaction, and specific behaviors | 0 | 0 |
| 136 | 6 | 58 | 421 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(10):5395-5400 Weiler IJ; Irwin SA; Klintsova AY; Spencer CM; Brazelton AD; et al. Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation | 102 | 192 |
| 137 | 4 | 58 | 841 2001 AMERICAN JOURNAL ON MENTAL RETARDATION 106(5):389-400 Sudhalter V; Belser RC Conversational characteristics of children with fragile x syndrome: Tangential language | 5 | 8 |
| 138 | 10 | 58 | 882 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(19):16439-16446 Kamath-Loeb AS; Loeb LA; Johansson E; Burgers PMJ; Fry M Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)(n) trinucleotide repeat sequence | 4 | 44 |
| 139 | 7 | 58 | 1052 2002 NUCLEIC ACIDS RESEARCH 30(17):3672-3681 Weisman-Shomer P; Cohen E; Fry M Distinct domains in the CArG-box binding factor A destabilize tetraplex forms of the fragile X expanded sequence d(CGG)(n) | 2 | 3 |
| 140 | 14 | 58 | 1099 2003 AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 118B(1):81-88 Barnea-Goraly N; Eliez S; Hedeus M; Menon V; White CD; et al. White matter tract alterations in fragile X syndrome: Preliminary evidence from diffusion tensor imaging | 0 | 6 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 141 | 12 | 58 | 1229 2004 DEVELOPMENTAL BIOLOGY 270(2):290-307 Zhang YQ; Matthies HJG; Mancuso J; Andrews HK; Woodruff E; et al. The Drosophila fragile X-related gene regulates axoneme differentiation during spermatogenesis | 3 | 3 |
| 142 | 3 | 57 | 280 1996 MOLECULAR AND CELLULAR BIOLOGY 16(7):3825-3832 Siomi MC; Zhang Y; Siomi H; Dreyfuss G Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them | 58 | 109 |
| 143 | 11 | 57 | 392 1997 JOURNAL OF INHERITED METABOLIC DISEASE 20(2):139-151 Hoogeveen AT; Oostra BA The fragile X syndrome | 6 | 10 |
| 144 | 11 | 57 | 615 1999 HUMAN BIOLOGY 71(1):55-68 Arrieta I; Gil A; Nunez T; Telez M; Martinez B; et al. Stability of the FMRI CGG repeat in a Basque sample | 4 | 5 |
| 145 | 10 | 57 | 980 2002 DEVELOPMENTAL PSYCHOBIOLOGY 41(2):133-146 Keysor CS; Mazzocco MMM; McLeod DR; Hoehn-Saric R Physiological arousal in females with fragile X or Turner syndrome | 1 | 2 |
| 146 | 25 | 57 | 1006 2002 HUMAN MOLECULAR GENETICS 11(24):3007-3017 Mazroui R; Huot ME; Tremblay S; Filion C; Labelle Y; et al. Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression | 24 | 31 |
| 147 | 1 | 57 | 1155 2003 JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS 24(4):267-275 Johnston C; Hessl D; Blasey C; Eliez S; Erba H; et al. Factors associated with parenting stress in mothers of children with fragile X syndrome | 0 | 1 |
| 148 | 13 | 57 | 1254 2004 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 89(9):4569-4574 Welt CK; Smith PC; Taylor AE Evidence of early ovarian aging in fragile X premutation carriers | 0 | 0 |
| 149 | 7 | 57 | 1326 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(10):3615-3620 Menon V; Leroux J; White CD; Reiss AL Frontostriatal deficits in fragile X syndrome: Relation to FMR1 gene expression | 0 | 0 |
| 150 | 5 | 56 | 241 1996 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 61:689-697 Liu Q; Siomi H; Siomi MC; Fischer U; Zhang Y; et al. Molecular characterization of the protein products of the fragile X syndrome gene and the survival of motor neurons gene | 2 | 10 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 151 | 14 | 56 | 1145 2003 HUMAN MOLECULAR GENETICS 12(9):949-959 Willemsen R; Hoogeveen-Westerveld M; Reis S; Holstege J; Severijnen LAWFM; et al. The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome | 11 | 19 |
| 152 | 26 | 56 | 1154 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(18):15669-15678 Sung YJ; Dolzhanskaya N; Nolin SL; Brown T; Currie JR; et al. The fragile X mental retardation protein FMRP binds elongation factor 1A mRNA and negatively regulates its translation in vivo | 8 | 13 |
| 153 | 11 | 56 | 1360 2005 NEURON 45(5):753-764 McBride SMJ; Choi CH; Wang Y; Liebelt D; Braunstein E; et al. Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome | 1 | 1 |
| 154 | 2 | 55 | 254 1996 HUMAN GENETICS 98(2):151-157 Kramer PR; Pearson CE; Sinden RR Stability of triplet repeats of myotonic dystrophy and fragile X loci in human mutator mismatch repair cell lines | 2 | 27 |
| 155 | 19 | 55 | 738 2000 HUMAN MOLECULAR GENETICS 9(10):1487-1493 Tamanini F; Kirkpatrick LL; Schonkeren J; van Unen L; Bontekoe C; et al. The fragile X-related proteins FXR1P and FXR2P contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins | 9 | 14 |
| 156 | 21 | 55 | 740 2000 HUMAN MOLECULAR GENETICS 9(19):2909-2918 Crawford DC; Wilson B; Sherman SL Factors involved in the initial mutation of the fragile X CGG repeat as determined by sperm small pool PCR | 3 | 11 |
| 157 | 15 | 55 | 832 2001 AMERICAN JOURNAL OF MEDICAL GENETICS 103(1):81-90 Sun HT; Cohen S; Kaufmann WE Annexin-1 is abnormally expressed in fragile X syndrome: Two-dimensional electrophoresis study in lymphocytes | 4 | 9 |
| 158 | 12 | 55 | 840 2001 AMERICAN JOURNAL ON MENTAL RETARDATION 106(3):216-230 Roberts JE; Mirrett P; Burchinal M Receptive and expressive communication development of young males with fragile X syndrome | 6 | 10 |
| 159 | 15 | 55 | 1141 2003 GENETICS IN MEDICINE 5(5):378-384 Skinner D; Sparkman KL; Bailey DB Screening for fragile X syndrome: Parent attitudes and perspectives | 1 | 1 |
| 160 | 33 | 55 | 1193 2003 TRENDS IN BIOCHEMICAL SCIENCES 28(3):152-158 Jin P; Warren ST New insights into fragile X syndrome: from molecules to neurobehaviors | 18 | 34 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 161 | 15 | 55 | 1231 2004 EMBO JOURNAL 23(16):3346-3355 Rackham O; Brown CM Visualization of RNA-protein interactions in living cells: FMRP and IMP1 interact on mRNAs | 3 | 4 |
| 162 | 31 | 55 | 1243 2004 GROWTH HORMONE & IGF RESEARCH 14:S158-S165 Mandel JL; Biancalana V Fragile X mental retardation syndrome: from pathogenesis to diagnostic issues | 0 | 0 |
| 163 | 15 | 55 | 1248 2004 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 291(4):460-469 Jacquemont S; Hagerman RJ; Leehey MA; Hall DA; Levine RA; et al. Penetrance of the fragile X - Associated tremor/ataxia syndrome in a premutation carrier population | 6 | 15 |
| 164 | 24 | 55 | 1287 2004 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 10(1):25-30 Hagerman PJ; Hagerman RJ Fragile X-associated tremor/ataxia syndrome (FXTAS) | 0 | 1 |
| 165 | 1 | 54 | 5 1995 AMERICAN JOURNAL OF HUMAN GENETICS 57(3):609-618 DEGRAAFF E; WILLEMSEN R; ZHONG N; DEDIESMULDERS CEM; BROWN WT; et al. INSTABILITY OF THE CGG REPEAT AND EXPRESSION OF THE FMR1 PROTEIN IN A MALE FRAGILE-X PATIENT WITH A LUNG-TUMOR | 26 | 32 |
| 166 | 1 | 54 | 424 1997 PSYCHIATRY RESEARCH-NEUROIMAGING 75(1):31-48 Kates WR; Abrams MT; Kaufmann WE; Breiter SN; Reiss AL Reliability and validity of MRI measurement of the amygdala and hippocampus in children with fragile X syndrome | 20 | 63 |
| 167 | 5 | 54 | 545 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 83(4):268-279 Miller LJ; McIntosh DN; McGrath J; Shyu V; Lampe M; et al. Electrodermal responses to sensory stimuli in individuals with fragile X syndrome: A preliminary report | 32 | 41 |
| 168 | 4 | 54 | 605 1999 EPILEPSIA 40(8):1092-1099 Musumeci SA; Hagerman RJ; Ferri R; Bosco P; Dalla Bernardina B; et al. Epilepsy and EEG findings in males with fragile X syndrome | 10 | 19 |
| 169 | 10 | 54 | 804 2000 OPTOMETRY AND VISION SCIENCE 77(11):592-599 Block SS; Brusca-Vega R; Pizzi WJ; Berry-Kravis E; Maino DM; et al. Cognitive and visual processing skills and their relationship to mutation size in full and premutation female fragile X carriers | 0 | 0 |
| 170 | 8 | 54 | 837 2001 AMERICAN JOURNAL OF PSYCHIATRY 158(7):1040-1051 Kwon H; Menon V; Eliez S; Warsofsky IS; White CD; et al. Functional neuroanatomy of visuospatial working memory in fragile X syndrome: Relation to behavioral and molecular measures | 11 | 24 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 171 | 11 | 54 | 1011 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(40):37804-37810 Ohashi S; Koike K; Omori A; Ichinose S; Ohara S; et al. Identification of mRNA/protein (mRNP) complexes containing Pur alpha, mStaufen, Fragile X Protein, and myosin Va and their association with rough endoplasmic reticulum equipped with a kinesin motor | 18 | 48 |
| 172 | 7 | 54 | 1153 2003 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 33(1):55-67 Lesniak-Karpiak K; Mazzocco MMM; Ross JL Behavioral assessment of social anxiety in females with Turner or fragile X syndrome | 0 | 6 |
| 173 | 20 | 54 | 1257 2004 JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS 25(6):392-398 Goodlin-Jones BL; Tassone F; Gane LW Autistic spectrum disorder and the fragile X premutation | 0 | 0 |
| 174 | 21 | 54 | 1291 2004 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 10(1):53-59 Beckel-Mitchener A; Greenough WT Correlates across the structural, functional, and molecular phenotypes of fragile X syndrome | 0 | 2 |
| 175 | 5 | 53 | 260 1996 HUMAN MOLECULAR GENETICS 5(8):1083-1091 Eberhart DE; Malter HE; Feng Y; Warren ST The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals | 93 | 132 |
| 176 | 8 | 53 | 538 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 82(1):25-30 Abrams MT; Kaufmann WE; Rousseau F; Oostra BA; Wolozin B; et al. FMR1 gene expression in olfactory neuroblasts from two males with fragile X syndrome | 8 | 11 |
| 177 | 11 | 53 | 648 1999 NEUROSCIENCE 94(1):185-192 Paradee W; Melikian HE; Rasmussen DL; Kenneson A; Conn PJ; et al. Fragile X mouse: Strain effects of knockout phenotype and evidence suggesting deficient amygdala function | 23 | 42 |
| 178 | 10 | 53 | 800 2000 NEUROSCIENCE RESEARCH COMMUNICATIONS 26(3):255-263 de Vries BBA; Oostra BA The fragile X syndrome: A model for mental retardation | 0 | 0 |
| 179 | 15 | 53 | 847 2001 BRAIN 124:1610-1618 Eliez S; Blasey CM; Freund LS; Hastie T; Reiss AL Brain anatomy, gender and IQ in children and adolescents with fragile X syndrome | 9 | 15 |
| 180 | 0 | 53 | 1009 2002 JOURNAL OF BACTERIOLOGY 184(1):177-182 Semsey S; Blaha B; Koles K; Orosz L; Papp PP Site-specific integrative elements of rhizobiophage 16-3 can integrate into proline tRNA (CGG) genes in different bacterial genera | 1 | 6 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 181 | 4 | 53 | 1012 2002 JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES 43(7):949-957 von Gontard A; Backes M; Laufersweiler-Plass C; Wendland C; Lehmkuhl G; et al. Psychopathology and familial stress - comparison of boys with Fragile X syndrome and Spinal Muscular Atrophy | 0 | 1 |
| 182 | 20 | 53 | 1035 2002 MOLECULAR AND CELLULAR BIOLOGY 22(24):8438-8447 Siomi MC; Higashijima K; Ishizuka A; Siomi H Casein kinase II phosphorylates the fragile X mental retardation protein and modulates its biological properties | 14 | 16 |
| 183 | 35 | 53 | 1120 2003 BIOLOGY OF THE CELL 95(3-4):221-228 Schaeffer C; Beaulande M; Ehresmann C; Ehresmann B; Moine H The RNA binding protein FMRP: new connections and missing links | 3 | 8 |
| 184 | 34 | 53 | 1146 2003 HUMAN MOLECULAR GENETICS 12(14):1689-1698 Bardoni B; Castets M; Huot ME; Schenck A; Adinolfi S; et al. 82-FIP, a novel FMRP (Fragile X Mental Retardation Protein) interacting protein, shows a cell cycle-dependent intracellular localization | 8 | 8 |
| 185 | 17 | 53 | 1149 2003 HUMAN MOLECULAR GENETICS 12(24):3295-3305 Ceman S; O'Donnell WT; Reed M; Patton S; Pohl J; et al. Phosphorylation influences the translation state of FMRP-associated polyribosomes | 12 | 15 |
| 186 | 23 | 53 | 1328 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(42):15201-15206 Lu R; Wang HP; Liang Z; Ku L; O'Donnell WT; et al. The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development | 3 | 3 |
| 187 | 1 | 53 | 1333 2004 QUALITATIVE HEALTH RESEARCH 14(6):741-759 Medved MI; Brockmeier J Making sense of traumatic experiences: Telling your life with fragile X syndrome | 0 | 0 |
| 188 | 0 | 52 | 152 1995 PEDIATRICS 95(5):744-752 BAUMGARDNER TL; REISS AL; FREUND LS; ABRAMS MT SPECIFICATION OF THE NEUROBEHAVIORAL PHENOTYPE IN MALES WITH FRAGILE-X SYNDROME | 49 | 75 |
| 189 | 7 | 52 | 517 1999 AMERICAN JOURNAL OF HUMAN GENETICS 65(3):680-688 Nolin SL; Houck GE; Gargano AD; Blumstein H; Dobkin CS; et al. FMR1 CCG-repeat instability by single sperm and lymphocytes of fragile-X premutation males | 8 | 15 |
| 190 | 16 | 52 | 654 2000 AMERICAN JOURNAL OF HUMAN GENETICS 66(2):480-493 Crawford DC; Schwartz CE; Meadows KL; Newman JL; Taft LF; et al. Survey of the fragile X syndrome CGG repeat and the short-tendem-repeat and single-nucleotide-polymorphism haplotypes in an African American population | 9 | 18 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 191 | 4 | 52 | 709 2000 BRAIN AND COGNITION 44(3):387-401 Munir F; Cornish KM; Wilding J Nature of the working memory deficit in Fragile-X syndrome | 8 | 9 |
| 192 | 2 | 52 | 924 2001 REVISTA DE NEUROLOGIA 33:S65-S70 Calvani M; D'Iddio S; de Gaetano A; Mariotti P; Mosconi L; et al. L-acetylcarnityne treatment on fragile X patients hyperactive behaviour | 0 | 0 |
| 193 | 16 | 52 | 1033 2002 MICROSCOPY RESEARCH AND TECHNIQUE 57(3):179-186 Keysor CS; Mazzocco MMM A developmental approach to understanding fragile X syndrome in females | 8 | 9 |
| 194 | 12 | 52 | 1049 2002 NEURON 34(6):961-972 Morales J; Hiesinger PR; Schroeder AJ; Kume K; Verstreken P; et al. Drosophila fragile X protein, DFXR, regulates neuronal morphology and function in the brain | 28 | 37 |
| 195 | 17 | 52 | 1059 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(24):15758-15763 Qin M; Kang J; Smith CB Increased rates of cerebral glucose metabolism in a mouse model of fragile X mental retardation | 5 | 6 |
| 196 | 36 | 52 | 1148 2003 HUMAN MOLECULAR GENETICS 12(23):3087-3096 Mazroui R; Huot ME; Tremblay S; Boilard N; Labelle Y; et al. Fragile X Mental Retardation protein determinants required for its association with polyribosomal mRNPs | 4 | 4 |
| 197 | 15 | 52 | 1346 2005 DEVELOPMENTAL CELL 8(1):43-52 Zarnescu DC; Jin P; Betschinger J; Nakamoto M; Wang Y; et al. Fragile X protein functions with Lgl and the PAR complex in flies and mice | 0 | 0 |
| 198 | 0 | 51 | 4 1995 AMERICAN JOURNAL OF HUMAN GENETICS 57(2):351-361 ZHONG N; YANG WH; DOBKIN C; BROWN WT FRAGILE-X GENE INSTABILITY - ANCHORING AGGS AND LINKED MICROSATELLITES | 54 | 82 |
| 199 | 5 | 51 | 343 1997 AMERICAN JOURNAL OF MEDICAL GENETICS 73(4):463-469 Ritchie RJ; Chakrabarti L; Knight SJL; Harding RM; Davies KE Population genetics of the FRAXE and FRAXF GCC repeats, and a novel CGG repeat, in Xq28 | 2 | 6 |
| 200 | 1 | 51 | 391 1997 JOURNAL OF CLINICAL INVESTIGATION 100(2):331-338 Jakala P; Hanninen T; Ryynanen M; Laakso M; Partanen K; et al. Fragile-X: Neuropsychological test performance, CGG triplet repeat lengths, and hippocampal volumes | 13 | 21 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 201 | 7 | 51 | 495 1998 JOURNAL OF MEDICAL GENETICS 35(2):103-111 Wohrle D; Salat U; Glaser D; Mucke J; Meisel-Stosiek M; et al. Unusual mutations in high functioning fragile X males: apparent instability of expanded unmethylated CGG repeats | 19 | 32 |
| 202 | 29 | 51 | 975 2002 CURRENT OPINION IN GENETICS & DEVELOPMENT 12(3):278-283 Hagerman RJ; Hagerman PJ The fragile X premutation: into the phenotypic fold | 15 | 25 |
| 203 | 14 | 51 | 1015 2002 JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS 23(6):416-423 Loesch DZ; Huggins RM; Bui QM; Epstein JL; Taylor AK; et al. Effect of the deficits of fragile X mental retardation protein on cognitive status of fragile X males and females assessed by robust pedigree analysis | 6 | 6 |
| 204 | 11 | 51 | 1212 2004 AMERICAN JOURNAL ON MENTAL RETARDATION 109(3):208-218 Philofsky A; Hepburn SL; Hayes A; Hagerman R; Rogers SJ Linguistic and cognitive functioning and autism symptoms in young children with fragile X syndrome | 0 | 1 |
| 205 | 10 | 50 | 180 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(1):203-208 Chiurazzi P; Macpherson J; Sherman S; Neri G Significance of linkage disequilibrium between the fragile X locus and its flanking markers | 18 | 25 |
| 206 | 0 | 50 | 265 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(40):24325-24328 Godde JS; Kass SU; Hirst MC; Wolffe AP Nucleosome assembly on methylated CGG triplet repeats in the Fragile X Mental Retardation gene 1 promoter | 5 | 41 |
| 207 | 31 | 50 | 599 1999 CURRENT OPINION IN PSYCHIATRY 12(5):573-578 Harris SW; Hagerman RJ Fragile X syndrome: new developments | 2 | 2 |
| 208 | 12 | 50 | 616 1999 HUMAN MOLECULAR GENETICS 8(5):863-869 Tamanini F; Bontekoe C; Bakker CE; van Unen L; Anar B; et al. Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations | 30 | 39 |
| 209 | 12 | 50 | 749 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(3):2231-2238 Weisman-Shomer P; Naot Y; Fry M Tetrahelical forms of the fragile X syndrome expanded sequence d(CGG)(n) are destabilized by two heterogeneous nuclear ribonucleoprotein-related telomeric DNA-binding proteins | 7 | 10 |
| 210 | 17 | 50 | 1104 2003 AMERICAN JOURNAL ON MENTAL RETARDATION 108(6):373-390 Hatton DD; Wheeler AC; Skinner ML; Bailey DB; Sullivan KM; et al. Adaptive behavior in children with fragile X syndrome | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 211 | 19 | 50 | 1185 2003 NUCLEIC ACIDS RESEARCH 31(14):3963-3970 Weisman-Shomer P; Cohen E; Hershco I; Khateb S; Wolfovitz-Barchad O; et al. The cationic porphyrin TMPyP4 destabilizes the tetraplex form of the fragile X syndrome expanded sequence d(CGG)(n) | 3 | 5 |
| 212 | 6 | 50 | 1215 2004 ARCHIVES OF GENERAL PSYCHIATRY 61(3):281-288 Garrett AS; Menon V; MacKenzie K; Reiss AL Here's looking at you, kid - Neural systems underlying face and gaze processing in fragile X syndrome | 0 | 1 |
| 213 | 5 | 50 | 1252 2004 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 34(1):41-48 Seltzer MM; Abbeduto L; Krauss MW; Greenberg J; Swe A Comparison groups in autism family research: Down syndrome, fragile X syndrome, and schizophrenia | 0 | 2 |
| 214 | 1 | 50 | 1297 2004 MOLECULAR MICROBIOLOGY 54(3):742-754 Blaha B; Semsey S; Ferenczi S; Csiszovszki Z; Papp PP; et al. A proline tRNA(CGG) gene encompassing the attachment site of temperate phage 16-3 is functional and convertible to suppressor tRNA | 0 | 0 |
| 215 | 22 | 50 | 1331 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(50):17504-17509 Weiler IJ; Spangler CC; Klintsova AY; Grossman AW; Kim SH; et al. Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses | 0 | 0 |
| 216 | 18 | 50 | 1338 2005 AMERICAN JOURNAL OF MEDICAL GENETICS PART A 132A(1):25-32 Skinner M; Hooper S; Hatton DD; Robert J; Mirrett P; et al. Mapping nonverbal IQ in young boys with fragile X syndrome | 0 | 0 |
| 217 | 0 | 49 | 113 1995 HUMAN MOLECULAR GENETICS 4(1):45-49 DEGRAAFF E; ROUILLARD P; WILLEMS PJ; SMITS APT; ROUSSEAU F; et al. HOTSPOT FOR DELETIONS IN THE CGG REPEAT REGION OF FMR1 IN FRAGILE-X PATIENTS | 31 | 46 |
| 218 | 0 | 49 | 257 1996 HUMAN MOLECULAR GENETICS 5(3):319-330 Eichler EE; Macpherson JN; Murray A; Jacobs PA; Chakravarti A; et al. Haplotype and interspersion analysis of the FMR1 CGG repeat identifies two different mutational pathways for the origin of the fragile X syndrome | 32 | 51 |
| 219 | 1 | 49 | 291 1996 REVISTA MEDICA DE CHILE 124(7):865-872 Jara L; Avendano I; Aspillaga M; Blanco R Molecular and genetic features of fragile X syndrome. A review | 0 | 0 |
| 220 | 10 | 49 | 425 1997 REVISTA DE NEUROLOGIA 25(143):1068-1071 EstevezGonzalez A; Roig C; Piles S; Pineda M; GarciaSanchez C Fragile-X syndrome and mental retardation | 1 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 221 | 14 | 49 | 867 2001 GENETIC EPIDEMIOLOGY 20(1):129-144 Sharma D; Gupta M; Thelma BK Expansion mutation frequency and CGG/GCC repeat polymorphism in FMR1 and FMR2 genes in an Indian population | 4 | 6 |
| 222 | 20 | 49 | 1001 2002 GENETICS AND MOLECULAR BIOLOGY 25(1):1-6 de Diego Y; Hmadcha A; Moron F; Lucas M; Carrasco M; et al. Fragile X founder effect and distribution of CGG repeats among the mentally retarded population of Andalusia, South Spain | 0 | 0 |
| 223 | 27 | 49 | 1233 2004 EXPERIMENTAL NEUROLOGY 189(2):343-353 Schrier M; Severijnen LA; Reis S; Rife M; van't Padje S; et al. Transport kinetics of FMRP containing the I304N mutation of severe fragile X syndrome in neurites of living rat PC12 cells | 0 | 0 |
| 224 | 11 | 49 | 1241 2004 GENOMICS 83(1):106-118 Naumann F; Remus R; Schmitz B; Doerfler W Gene structure and expression of the 5 '-(CGG)(n)-3 '-binding protein (CGGBP1) | 0 | 1 |
| 225 | 21 | 49 | 1344 2005 BRAIN AND COGNITION 57(1):53-60 Cornish K; Kogan C; Turk J; Manly T; James N; et al. The emerging fragile X premutation phenotype: Evidence from the domain of social cognition | 0 | 0 |
| 226 | 9 | 48 | 372 1997 FOLIA HISTOCHEMICA ET CYTOBIOLOGICA 35(3):135-141 Szot M The fragile X syndrome | 0 | 0 |
| 227 | 20 | 48 | 696 2000 AMERICAN JOURNAL OF MEDICAL GENETICS 97(3):183-188 Willemsen R; Oostra BA FMRP detection assay for the diagnosis of the fragile X syndrome | 2 | 4 |
| 228 | 3 | 48 | 871 2001 GENOME RESEARCH 11(8):1382-1391 Mathews DJ; Kashuk C; Brightwell G; Eichler EE; Chakravarti A Sequence variation within the fragile x locus | 0 | 3 |
| 229 | 14 | 48 | 1205 2004 AMERICAN JOURNAL OF MEDICAL GENETICS PART A 126A(1):9-17 Kau ASM; Tierney E; Bukelis I; Stump MH; Kates WR; et al. Social behavior profile in young males with fragile X syndrome: Characteristics and specificity | 0 | 2 |
| 230 | 15 | 48 | 1284 2004 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 10(1):3-10 Bailey DB Newborn screening for fragile X syndrome | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 231 | 6 | 47 | 389 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272(27):16761-16768 Deissler H; Wilm M; Genc B; Schmitz B; Ternes T; et al. Rapid protein sequencing by tandem mass spectrometry and cDNA cloning of p20-CGGBP - A novel protein that binds to the unstable triplet repeat 5'-d(CGG)(n)-3' in the human FMR1 gene | 5 | 17 |
| 232 | 13 | 47 | 410 1997 MOLECULAR CELL 1(1):109-118 Feng Y; Absher D; Eberhart DE; Brown V; Malter HE; et al. FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association | 89 | 134 |
| 233 | 9 | 47 | 547 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 83(4):286-295 Kaufmann WE; Abrams MT; Chen WM; Reiss AL Genotype, molecular phenotype, and cognitive phenotype: Correlations in fragile X syndrome | 30 | 36 |
| 234 | 3 | 47 | 799 2000 NEUROPSYCHOLOGIA 38(9):1261-1270 Munir F; Cornish KM; Wilding J A neuropsychological profile of attention deficits in young males with fragile X syndrome | 17 | 21 |
| 235 | 18 | 47 | 851 2001 CELL 107(4):477-487 Brown V; Jin P; Ceman S; Darnell JC; O'Donnell WT; et al. Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome | 80 | 162 |
| 236 | 28 | 47 | 872 2001 HUMAN GENETICS 108(6):450-458 Weinhausel A; Haas OA Evaluation of the fragile X (FRAXA) syndrome with methylation-sensitive PCR | 2 | 6 |
| 237 | 14 | 47 | 874 2001 HUMAN MOLECULAR GENETICS 10(14):1449-1454 Kenneson A; Zhang FP; Hagedorn CH; Warren ST Reduced FMRP and increased FMR1 transcription is proportionally associated with CGG repeat number in intermediate-length and premutation carriers | 36 | 46 |
| 238 | 4 | 47 | 896 2001 JOURNAL OF SPECIAL EDUCATION 34(4):194-202 Symons FJ; Clark RD; Roberts JP; Bailey DB Classroom behavior of elementary school-age boys with fragile X syndrome | 2 | 3 |
| 239 | 3 | 47 | 904 2001 NEUROPSYCHOLOGY 15(2):290-299 Bennetto L; Pennington BF; Porter D; Taylor AK; Hagerman RJ Profile of cognitive functioning in women with the fragile X mutation | 10 | 13 |
| 240 | 6 | 47 | 908 2001 NUCLEIC ACIDS RESEARCH 29(22):4684-4690 Fojtik P; Vorlickova M The fragile X chromosome (GCC) repeat folds into a DNA tetraplex at neutral pH | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 241 | 10 | 47 | 961 2002 AMERICAN JOURNAL OF NEURORADIOLOGY 23(10):1757-1766 Brunberg JA; Jacquemont S; Hagerman RJ; Berry-Kravis EM; Grigsby J; et al. Fragile X premutation carriers: Characteristic MR imaging findings of adult male patients with progressive cerebellar and cognitive dysfunction | 17 | 27 |
| 242 | 5 | 47 | 1225 2004 COGNITIVE NEUROPSYCHOLOGY 21(6):579-596 Keenan JM; Simon JA Inference deficits in women with Fragile X Syndrome: A problem in working memory | 0 | 0 |
| 243 | 14 | 47 | 1226 2004 CURRENT BIOLOGY 14(12):1025-1034 Xu KY; Bogert BA; Li WJ; Su K; Lee A; et al. The fragile X-related gene affects the crawling behavior of Drosophila larvae by regulating the mRNA level of the DEG/ENaC protein pickpocket1 | 2 | 3 |
| 244 | 8 | 47 | 1343 2005 BIOCHEMICAL JOURNAL 386:297-303 Kumari D; Gabrielian A; Wheeler D; Usdin K The roles of Sp1, Sp3, USF1/USF2 and NRF-1 in the regulation and three-dimensional structure of the Fragile X mental retardation gene promoter | 0 | 0 |
| 245 | 21 | 47 | 1355 2005 JOURNAL OF BIOLOGICAL CHEMISTRY 280(7):5750-5763 Garnon J; Lachance C; Di Marco S; Hel Z; Marion D; et al. Fragile X-related protein FXR1P regulates proinflammatory cytokine tumor necrosis factor expression at the post-transcriptional level | 0 | 0 |
| 246 | 1 | 46 | 121 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(48):28970-28977 NADEL Y; WEISMANSHOMER P; FRY M THE FRAGILE-X SYNDROME SINGLE-STRAND D(CGG)(N) NUCLEOTIDE REPEATS READILY FOLD BACK TO FORM UNIMOLECULAR HAIRPIN STRUCTURES | 17 | 50 |
| 247 | 11 | 46 | 644 1999 MOLECULAR AND CELLULAR BIOLOGY 19(12):7925-7932 Ceman S; Brown V; Warren ST Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex | 50 | 76 |
| 248 | 8 | 46 | 692 2000 AMERICAN JOURNAL OF MEDICAL GENETICS 95(4):307-315 Gould EL; Loesch DZ; Martin MJ; Hagerman RJ; Armstrong SM; et al. Melatonin profiles and sleep characteristics in boys with fragile X syndrome: A preliminary study | 13 | 19 |
| 249 | 3 | 46 | 707 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 278(3):833-838 Patel PK; Bhavesh NS; Hosur RV Cation-dependent conformational switches in d-TGGCGGC containing two triplet repeats of Fragile X Syndrome: NMR observations | 4 | 9 |
| 250 | 2 | 46 | 721 2000 DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY 42(11):768-774 Sheldon L; Turk J Monozygotic boys with fragile X syndrome | 1 | 2 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 251 | 11 | 46 | 970 2002 BRAIN RESEARCH 927(1):8-17 Nielsen DM; Derber WJ; McClellan DA; Crnic LS Alterations in the auditory startle response in Fmr1 targeted mutant mouse models of fragile X syndrome | 11 | 15 |
| 252 | 10 | 46 | 1003 2002 GENOMICS 80(4):423-432 Peier AM; Nelson DL Instability of a premutation-sized CGG repeat in FMR1 YAC transgenic mice | 2 | 3 |
| 253 | 10 | 46 | 1100 2003 AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 121B(1):119-127 Aziz M; Stathopulu E; Callias M; Taylor C; Turk J; et al. Clinical features of boys with fragile X premutations and intermediate alleles | 0 | 8 |
| 254 | 17 | 46 | 1354 2005 JOURNAL OF BIOLOGICAL CHEMISTRY 280(6):4498-4503 Mulvihill DJ; Edamura KN; Hagerman KA; Pearson CE; Wang YH Effect of CAT or AGG interruptions and CpG methylation on nucleosome assembly upon trinucleotide repeats on spinocerebellar ataxia, type 1 and fragile X syndrome | 0 | 0 |
| 255 | 26 | 46 | 1363 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102(6):2180-2185 Aschrafi A; Cunningham BA; Edelman GM; Vanderklish PW The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain | 0 | 0 |
| 256 | 2 | 45 | 182 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(1):220-225 Eichler EE; Nelson DL Genetic variation and evolutionary stability of the FMR1 CGG repeat in six closed human populations | 14 | 18 |
| 257 | 0 | 45 | 277 1996 MEDICAL ANTHROPOLOGY QUARTERLY 10(4):537-550 Nelkin D The social dynamics of genetic testing: The case of Fragile-X | 1 | 6 |
| 258 | 1 | 45 | 282 1996 NIMHANS JOURNAL 14(3):201-207 Suresh KP; Girimaji SR; Manjunatha KR Newer genetics in mental retardation .1. Fragile X syndrome and triplet repeat mutations | 0 | 1 |
| 259 | 0 | 45 | 626 1999 JOURNAL OF EARLY INTERVENTION 22(2):137-151 Jackson SC; Roberts JE Family and professional congruence in communication assessments of preschool boys with fragile X syndrome | 0 | 0 |
| 260 | 24 | 45 | 796 2000 MOLECULAR MEDICINE TODAY 6(5):193-198 Kooy RF; Willemsen R; Oostra BA Fragile X syndrome at the turn of the century | 15 | 21 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 261 | 14 | 45 | 802 2000 NUCLEIC ACIDS RESEARCH 28(7):1535-1541 Weisman-Shomer P; Cohen E; Fry M Interruption of the fragile X syndrome expanded sequence d(CGG)(n) by interspersed d(AGG) trinucleotides diminishes the formation and stability of d(CGG)(n) tetrahelical structures | 6 | 11 |
| 262 | 15 | 45 | 875 2001 HUMAN MOLECULAR GENETICS 10(16):1693-1699 Bontekoe CJM; Bakker CE; Nieuwenhuizen IM; van der Linde H; Lans H; et al. Instability of a (CGG)(98) repeat in the Fmr1 promoter | 12 | 15 |
| 263 | 21 | 45 | 1190 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(24):14374-14378 Todd PK; Mack KJ; Malter JS The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95 | 8 | 13 |
| 264 | 9 | 45 | 1289 2004 MENTAL RETARDATION AND DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS 10(1):42-48 Berry-Kravis E; Potanos K Psychopharmacology in fragile X syndrome - Present and future | 0 | 0 |
| 265 | 17 | 45 | 1362 2005 NUCLEIC ACIDS RESEARCH 33(2):451-463 Napierala M; Michalowski D; de Mezer M; Krzyzosiak WJ Facile FMR1 mRNA structure regulation by interruptions in CGG repeats | 0 | 0 |
| 266 | 0 | 44 | 120 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(45):27014-27021 KANG SM; OHSHIMA K; SHIMIZU M; AMIRHAERI S; WELLS RD PAUSING OF DNA-SYNTHESIS IN-VITRO AT SPECIFIC LOCI IN CTG AND CGG TRIPLET REPEATS FROM HUMAN HEREDITARY-DISEASE GENES | 16 | 96 |
| 267 | 1 | 44 | 246 1996 EUROPEAN PSYCHIATRY 11(5):227-232 Barbe B; Franke P; Maier W; Leboyer M Fragile X syndrome .1. An overview on its genetic mechanism | 0 | 0 |
| 268 | 5 | 44 | 270 1996 JOURNAL OF MOLECULAR BIOLOGY 258(4):614-626 Shimizu M; Gellibolian R; Oostra BA; Wells RD Cloning, characterization and properties of plasmids containing CGG triplet repeats from the FMR-1 gene | 14 | 49 |
| 269 | 13 | 44 | 336 1997 AMERICAN JOURNAL OF HUMAN GENETICS 61(4):961-967 Gronskov K; Hjalgrim H; Bjerager MO; BrondumNielsen K Deletion of all CGG repeats plus flanking sequences in FMR1 does not abolish gene expression | 5 | 6 |
| 270 | 2 | 44 | 423 1997 PSYCHIATRIC GENETICS 7(3):115-119 ODwyer J; Holmes J; Mueller R; Taylor G The prevalence of Fragile-X syndrome in an institution for people with learning disability | 1 | 3 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 271 | 9 | 44 | 596 1999 CLINICAL GENETICS 55(5):346-351 Tassone F; Longshore J; Zunich J; Steinbach P; Salat U; et al. Tissue-specific methylation differences in a fragile X premutation carrier | 2 | 4 |
| 272 | 12 | 44 | 733 2000 GENETICS IN MEDICINE 2(4):242-248 Burman RW; Anoe KS; Popovich BW Fragile X full mutations ave more similar in siblings than in unrelated patients: further evidence for a familial factor in CGG repeat dynamics | 1 | 2 |
| 273 | 7 | 44 | 962 2002 AMERICAN JOURNAL OF OCCUPATIONAL THERAPY 56(5):538-546 Baranek GT; Chin YKH; Hess LMG; Yankee JG; Hatton DD; et al. Sensory processing correlates of occupational performance in children with fragile X syndrome: Preliminary findings | 1 | 1 |
| 274 | 7 | 44 | 1004 2002 HUMAN BRAIN MAPPING 16(4):206-218 Rivera SM; Menon V; White CD; Glaser B; Reiss AL Functional brain activation during arithmetic processing in females with fragile X Syndrome is related to FMRI protein expression | 7 | 14 |
| 275 | 0 | 44 | 1010 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(23):21041-21049 Vargason JM; Ho PS The effect of cytosine methylation on the structure and geometry of the Holliday junction - The structure of d(CCGGTACm(5)CGG) at 1.5 angstrom resolution | 0 | 9 |
| 276 | 18 | 44 | 1090 2003 AMERICAN JOURNAL OF MEDICAL GENETICS PART A 116A(1):44-51 Steyaert J; Legius E; Borghgraef M; Fryns JP A distinct neurocognitive phenotype in female fragile-X premutation carriers assessed with visual attention tasks | 0 | 4 |
| 277 | 17 | 44 | 1147 2003 HUMAN MOLECULAR GENETICS 12(23):3067-3074 Chen LS; Tassone F; Sahota P; Hagerman PJ The (CGG)(n) repeat element within the 5 ' untranslated region of the FMR1 message provides both positive and negative cis effects on in vivo translation of a downstream reporter | 3 | 3 |
| 278 | 16 | 44 | 1321 2004 NUCLEIC ACIDS RESEARCH 32(14):4145-4154 Khateb S; Weisman-Shomer P; Hershco I; Loeb LA; Fry M Destabilization of tetraplex structures of the fragile X repeat sequence (CGG)(n) is mediated by homolog-conserved domains in three members of the hnRNP family | 0 | 0 |
| 279 | 0 | 43 | 53 1995 ARCHIVES OF DISEASE IN CHILDHOOD 72(1):3-5 TURK J FRAGILE-X SYNDROME | 2 | 4 |
| 280 | 0 | 43 | 100 1995 EMBO JOURNAL 14(11):2401-2408 SIOMI MC; SIOMI H; SAUER WH; SRINIVASAN S; NUSSBAUM RL; et al. FXR1, AN AUTOSOMAL HOMOLOG OF THE FRAGILE-X MENTAL-RETARDATION GENE | 62 | 102 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 281 | 0 | 43 | 119 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(39):23090-23096 CHEN FM ACID-FACILITATED SUPRAMOLECULAR ASSEMBLY OF G-QUADRUPLEXES IN D(CGG)(4) | 10 | 37 |
| 282 | 0 | 43 | 151 1995 PEDIATRIC RESEARCH 38(5):638-643 BERRYKRAVIS E; HICAR M; CIURLIONIS R REDUCED CYCLIC-AMP PRODUCTION IN FRAGILE-X SYNDROME - CYTOGENETIC AND MOLECULAR CORRELATIONS | 4 | 4 |
| 283 | 5 | 43 | 183 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(1):226-233 Zhong N; Kajanoja E; Smits B; Pietrofesa J; Curley D; et al. Fragile X founder effects and new mutations in Finland | 14 | 26 |
| 284 | 3 | 43 | 196 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):302-308 deGraaff E; deVries BBA; Willemsen R; vanHemel JO; Mohkamsing S; et al. The fragile X phenotype in a mosaic male with a deletion showing expression of the FMR1 protein in 28% of the cells | 12 | 13 |
| 285 | 2 | 43 | 233 1996 CELL 85(2):237-245 Musco G; Stier G; Joseph C; Morelli MAC; Nilges M; et al. Three-dimensional structure and stability of the KH domain: Molecular insights into the fragile X syndrome | 22 | 178 |
| 286 | 1 | 43 | 263 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(8):4327-4334 Deissler H; BehnKrappa A; Doerfler W Purification of nuclear proteins from human HeLa cells that bind specifically to the unstable tandem repeat (CGG), in the human FMR1 gene | 11 | 24 |
| 287 | 13 | 43 | 337 1997 AMERICAN JOURNAL OF HUMAN GENETICS 61(6):1362-1369 Kenneson A; Cramer DW; Warren ST Fragile X premutations are not a major cause of early menopause | 13 | 22 |
| 288 | 12 | 43 | 351 1997 ANNALS OF MEDICINE 29(6):563-567 Oostra BA; Hoogeveen AT Animal model for fragile X syndrome | 3 | 8 |
| 289 | 4 | 43 | 639 1999 JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY 38(10):1294-1301 Murphy DGM; Mentis MJ; Pietrini P; Grady CL; Moore CJ; et al. Premutation female carriers of fragile X syndrome: A pilot study on brain anatomy and metabolism | 8 | 9 |
| 290 | 10 | 43 | 650 1999 RNA-A PUBLICATION OF THE RNA SOCIETY 5(9):1248-1258 Adinolfi S; Bagni C; Musco G; Gibson T; Mazzarella L; et al. Dissecting FMR1, the protein responsible for fragile X syndrome, in its structural and functional domains | 22 | 29 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 291 | 0 | 43 | 722 2000 EMBO JOURNAL 19(17):4745-4758 Yaremchuk A; Cusack S; Tukalo M Crystal structure of a eukaryote/archaeon-like prolyl-tRNA synthetase and its complex with tRNA(Pro)(CGG) | 0 | 31 |
| 292 | 15 | 43 | 795 2000 MOLECULAR DIAGNOSIS 5(3):169-178 Gold B; Radu D; Balanko A; Chiang CS Diagnosis of Fragile X syndrome by Southern blot hybridization using a chemiluminescent probe: A laboratory protocol | 0 | 1 |
| 293 | 5 | 43 | 839 2001 AMERICAN JOURNAL ON MENTAL RETARDATION 106(1):28-38 Belser RC; Sudhalter V Conversational characteristics of children with fragile X syndrome: Repetitive speech | 9 | 12 |
| 294 | 8 | 43 | 906 2001 NEUROSCIENCE 103(4):1043-1050 Chen L; Toth M Fragile X mice develop sensory hyperreactivity to auditory stimuli | 21 | 34 |
| 295 | 20 | 43 | 955 2002 AMERICAN JOURNAL OF MEDICAL GENETICS 110(3):226-233 Crawford DC; Meadows KL; Newman JL; Taft LF; Scott E; et al. Prevalence of the fragile x syndrome in African-Americans | 3 | 4 |
| 296 | 14 | 43 | 957 2002 AMERICAN JOURNAL OF MEDICAL GENETICS 111(3):243-252 Mingroni-Netto RC; Angeli CB; Auricchio MTBM; Leal-Mesquita ER; Ribeiro-dos-Santos AKC; et al. Distribution of CGG repeats and FRAXAC1/DXS548 alleles in South American populations | 1 | 3 |
| 297 | 8 | 43 | 998 2002 GENES & DEVELOPMENT 16(19):2491-2496 Caudy AA; Myers M; Hannon GJ; Hammond SM Fragile X-related protein and VIG associate with the RNA interference machinery | 26 | 109 |
| 298 | 15 | 43 | 1034 2002 MOLECULAR AND CELLULAR BIOLOGY 22(23):8332-8341 Otero YD; Severijnen LA; van Cappellen G; Schrier M; Oostra B; et al. Transport of fragile X mental retardation protein via granules in neurites of PC12 cells | 17 | 24 |
| 299 | 10 | 43 | 1060 2002 PSYCHONEUROENDOCRINOLOGY 27(7):855-872 Hessl D; Glaser B; Dyer-Friedman J; Blasey C; Hastie T; et al. Cortisol and behavior in fragile X syndrome | 6 | 9 |
| 300 | 9 | 43 | 1095 2003 AMERICAN JOURNAL OF MEDICAL GENETICS PART A 118A(2):115-121 Symons FJ; Clark RD; Hatton DD; Skinner M; Bailey DB Self-injurious behavior in young boys with fragile X syndrome | 0 | 3 |