#	Cited nodes	Nodes / Authors	GCS	LCS
4101	4	6794 1989 XENOBIOTICA 19(11):1319-1326 HAHNEMANN B; LEGRUM W; KOSS G; NETTER KJ INTERACTIONS OF HETEROCYCLIC MAILLARD PRODUCTS WITH THE HEPATIC-MICROSOMAL MONOOXYGENASE SYSTEM	0	0
4102	10	7900 1992 BIOCHEMICAL JOURNAL 286():289-294 HAHNEMANN B; SALONPAA P; PASANEN M; MAENPAA J; HONKAKOSKI P; JUVONEN R; LANG MA; PELKONEN O; RAUNIO H EFFECT OF PYRAZOLE, COBALT AND PHENOBARBITAL ON MOUSE-LIVER CYTOCHROME-P-450 2A-4/5 (CYP2A-4/5) EXPRESSION	37	16
4103	7	12974 2003 ARCHIV DER PHARMAZIE 335(11-12):526-534 Haidar S; Hartmann RW C16 and C17 substituted derivatives of pregnenolone and progesterone as inhibitors of 17 alpha-hydroxylase-C17,20- lyase: Synthesis and biological evaluation	0	0
4104	12	11962 2000 BIOCHEMISTRY 39(31):9419-9429 Haines DC; Sevrioukova IF; Peterson JA The FMN-binding domain of cytochrome P450BM-3: Resolution, reconstitution, and flavin analogue substitution	3	2
4105	25	12371 2001 BIOCHEMISTRY 40(45):13456-13465 Haines DC; Tomchick DR; Machius M; Peterson JA Pivotal role of water in the mechanism of P450BM-3	9	5
4106	26	9976 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 333(2):447-458 Haining RL; Hunter AP; Veronese ME; Trager WF; Rettie AE Allelic variants of human cytochrome P450 2C9: Baculovirus- mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms	94	21
4107	12	4670 1982 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 223(1):97-104 HAJEK KK; COOK NI; NOVAK RF MECHANISM OF INHIBITION OF MICROSOMAL DRUG-METABOLISM BY IMIDAZOLE	60	16
4108	5	4517 1982 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 108(2):664-672 HAJEK KK; NOVAK RF SPECTRAL AND METABOLIC PROPERTIES OF LIVER-MICROSOMES FROM IMIDAZOLE-PRETREATED RABBITS	35	12
4109	5	7489 1991 CARCINOGENESIS 12(4):697-702 HAJOS AKD; WINSTON GW DINITROPYRENE NITROREDUCTASE ACTIVITY OF PURIFIED NAD(P)H- QUINONE OXIDOREDUCTASE - ROLE IN RAT-LIVER CYTOSOL AND INDUCTION BY AROCLOR-1254 PRETREATMENT	35	3
4110	9	7867 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 295(2):223-229 HAJOS AKD; WINSTON GW ROLE OF CYTOSOLIC NAD(P)H-QUINONE OXIDOREDUCTASE AND ALCOHOL- DEHYDROGENASE IN THE REDUCTION OF PARA-NITROSOPHENOL FOLLOWING CHRONIC ETHANOL INGESTION	7	1
4111	3	9865 1995 PROGRESS IN LIPID RESEARCH 34(4):343-364 Hajra AK Glycerolipid biosynthesis in peroxisomes (microbodies)	33	0
4112	11	10014 1996 BIOCHEMICAL PHARMACOLOGY 51(1):61-69 Hakkak R; Korourian S; Ronis MJJ; IngelmanSundberg M; Badger TM Effects of diet and ethanol on the expression and localization of cytochromes P450 2E1 and P450 2C7 in the colon of male rats	14	3
4113	10	7982 1992 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 34(5):415-420 HAKKOLA J; MAENPAA J; MAYER RT; PARK SS; GELBOIN HV; PELKONEN O 7-ALKOXYQUINOLINE O-DEALKYLATION BY MICROSOMES FROM HUMAN LIVER AND PLACENTA	5	3
4114	31	10017 1996 BIOCHEMICAL PHARMACOLOGY 51(4):403-411 Hakkola J; Pasanen M; Hukkanen J; Pelkonen O; Maenpaa J; Edwards RJ; Boobis AR; Raunio H Expression of xenobiotic-metabolizing cytochrome P450 forms in human full-term placenta	64	25
4115	13	10604 1997 CARCINOGENESIS 18(2):391-397 Hakkola J; Pasanen M; Pelkonen O; Hukkanen J; Evisalmi S; Anttila S; Rane A; Mantyla M; Purkunen R; Saarikoski S; Tooming M; Raunio H Expression of CYP1B1 in human adult and fetal tissues and differential inducibility of CYP1B1 and CYP1A1 by Ah receptor ligands in human placenta and cultured cells	66	22
4116	23	8970 1994 BIOCHEMICAL PHARMACOLOGY 48(1):59-64 HAKKOLA J; PASANEN M; PURKUNEN R; SAARIKOSKI S; PELKONEN O; MAENPAA J; RANE A; RAUNIO H EXPRESSION OF XENOBIOTIC-METABOLIZING CYTOCHROME-P450 FORMS IN HUMAN ADULT AND FETAL LIVER	95	33
4117	86	11154 1998 CRITICAL REVIEWS IN TOXICOLOGY 28(1):35-72 Hakkola J; Pelkonen O; Pasanen M; Raunio H Xenobiotic-metabolizing cytochrome P450 enzymes in the human feto-placental unit: Role in intrauterine toxicity	41	11
4118	19	12382 2001 BIOLOGY OF THE NEONATE 80(3):193-201 Hakkola J; Raunio H; Purkunen R; Saarikoski S; Vahakangas K; Pelkonen O; Edwards RJ; Boobis AR; Pasanen M Cytochrome P450 3A expression in the human fetal liver: Evidence that CYP3A5 is expressed in only a limited number of fetal livers	4	1
4119	30	11373 1998 PHARMACOLOGY & TOXICOLOGY 82(5):209-217 Hakkola J; Tanaka E; Pelkonen O Developmental expression of cytochrome P450 enzymes in human liver	22	4
4120	5	2956 1976 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 173(1):121-124 HAKSAR A; LIN MT; PERON FG SOURCES OF REDUCING EQUIVALENTS FOR MICROSOMAL STEROID 21- HYDROXYLATION IN ISOLATED RAT ADRENAL-CELLS	2	1
4121	8	1964 1972 JOURNAL OF STEROID BIOCHEMISTRY 3(6):847-& HAKSAR A; PERON FG POSSIBLE FUNCTION OF PYRUVATE IN STEROIDOGENIC RESPONSE OF RAT ADRENAL CELL SUSPENSIONS TO ACTH, CYCLIC-3',5'-AMP AND DIBUTYRYL CYCLIC-3',5'-AMP	21	5
4122	9	7862 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 294(2):586-593 HALARNKAR PP; NOUROOZZADEH J; KUWANO E; JONES AD; HAMMOCK BD FORMATION OF CYCLIC PRODUCTS FROM THE DIEPOXIDE OF LONG-CHAIN FATTY ESTERS BY CYTOSOLIC EPOXIDE HYDROLASE	16	6
4123	10	6386 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 272(1):226-236 HALARNKAR PP; WIXTROM RN; SILVA MH; HAMMOCK BD CATABOLISM OF EPOXY FATTY ESTERS BY THE PURIFIED EPOXIDE HYDROLASE FROM MOUSE AND HUMAN-LIVER	27	7
4124	4	1902 1972 INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS 9(3):230-235 HALDAR I; MAHAJANI U; DATTA AG PURIFICATION AND PROPERTIES OF A SOLUBLE PEROXIDASE FROM THYROID-GLAND OF GOAT	7	4
4125	3	8069 1992 ENDOCRINOLOGY 131(5):2165-2172 HALES DB INTERLEUKIN-1 INHIBITS LEYDIG-CELL STEROIDOGENESIS PRIMARILY BY DECREASING 17-ALPHA-HYDROXYLASE C17-20 LYASE CYTOCHROME P450 EXPRESSION	64	2
4126	9	5198 1984 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 21(6):639-642 HALES DB; BETZ G STEROID INTERACTIONS WITH CYTOCHROME-P-450 FROM TESTIS MICROSOMES	2	1
4127	9	5644 1986 ENDOCRINOLOGY 119(2):811-818 HALES DB; BETZ G NADPH-CYTOCHROME-P-450 REDUCTASE FROM UNTREATED RAT TESTICULAR AND LIVER-MICROSOMES - ISOLATION AND COMPARISON	4	0
4128	4	7044 1990 ENDOCRINOLOGY 126(6):2800-2808 HALES DB; SHA L; PAYNE AH GLUCOCORTICOID AND CYCLIC ADENOSINE 3'5'-MONOPHOSPHATE-MEDIATED INDUCTION OF CHOLESTEROL SIDE-CHAIN CLEAVAGE CYTOCHROME-P450 (P450SCC) IN MA-10 TUMOR LEYDIG-CELLS - INCREASES IN MESSENGER- RNA ARE CYCLOHEXIMIDE SENSITIVE	28	6
4129	16	3644 1978 JOURNAL OF ENVIRONMENTAL PATHOLOGY AND TOXICOLOGY 1(3):315-337 HALEY TJ REVIEW OF THE LITERATURE OF ROTENONE 1,2,12,12A-TETRAHYDRO-8,9- DIMETHOXY-2-(1-METHYLETHENYL)-1-BENZOPYRANO[3,5-B]FURO[2,3- H][1]BENZOPYRAN-6(6H)-ONE	37	1
4130	50	10385 1996 PHYTOCHEMISTRY 43(1):1-21 Halkier BA Catalytic reactivities and structure/function relationships of cytochrome P450 enzymes	29	4
4131	12	9457 1995 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 322(2):369-377 HALKIER BA; NIELSEN HL; KOCH B; MOLLER BL PURIFICATION AND CHARACTERIZATION OF RECOMBINANT CYTOCHROME P450(TYR) EXPRESSED AT HIGH-LEVELS IN ESCHERICHIA-COLI	40	16
4132	3	10134 1996 CYTOCHROME P450, PT B 272():268-274 Halkier BA; Sibbesen O; Moller BL Isolation of plant and recombinant CYP79	2	0
4133	1	601 1967 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 26(2):138-& HALL CL; CRANE FL VARIATION IN INHIBITOR SENSITIVITY OF NADH-MENADIONE REDUCTASE FROM MITOCHONDRIA	2	2
4134	5	6995 1990 CHEMICO-BIOLOGICAL INTERACTIONS 76(2):181-192 HALL M; PARKER DK; GROVER PL; LU JYL; HOPKINS NE; ALWORTH WL EFFECTS OF 1-ETHYNYLPYRENE AND RELATED INHIBITORS OF P450 ISOZYMES UPON BENZO[A]PYRENE METABOLISM BY LIVER-MICROSOMES	22	5
4135	3	635 1967 BIOCHEMISTRY 6(9):2794-& HALL PF ELECTRON TRANSPORT IN RELATION TO STEROID BIOSYNTHESIS . INHIBITION OF SIDE-CHAIN CLEAVAGE OF CHOLESTEROL BY HYPERBARIC OXYGEN	24	16
4136	1	1679 1971 NATURE 232(5313):631-& HALL PF ROLE OF REDUCED TPN IN RESPONSE TO INTERSTITIAL CELL STIMULATING HORMONE	2	2
4137	12	1811 1972 BIOCHEMISTRY 11(15):2891-& HALL PF A POSSIBLE ROLE FOR TRANSHYDROGENATION IN SIDE-CHAIN CLEAVAGE OF CHOLESTEROL	21	5
4138	10	2044 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):195-207 HALL PF PROPERTIES OF SOLUBLE CYTOCHROMES P-450 FROM BOVINE ADRENOCORTICAL MITOCHONDRIA	8	3
4139	39	5504 1985 VITAMINS AND HORMONES-ADVANCES IN RESEARCH AND APPLICATIONS 42():315-368 HALL PF ROLE OF CYTOCHROMES-P-450 IN THE BIOSYNTHESIS OF STEROID- HORMONES	41	14
4140	32	5731 1986 STEROIDS 48(3-4):133-196 HALL PF CYTOCHROMES-P-450 AND THE REGULATION OF STEROID-SYNTHESIS	11	1
4141	10	2847 1975 JOURNAL OF BIOLOGICAL CHEMISTRY 250(6):2283-2286 HALL PF; LEWES JL; LIPSON ED ROLE OF MITOCHONDRIAL CYTOCHROME-P-450 FROM BOVINE ADRENAL- CORTEX IN SIDE-CHAIN CLEAVAGE OF 20S,22R-DIHYDROXYCHOLESTEROL	37	6
4142	9	3871 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(2):547-552 HALL PF; WATANUKI M; HAMKALO BA ADRENOCORTICAL CYTOCHROME-P-450 SIDE-CHAIN CLEAVAGE - PREPARATION OF MEMBRANE-BOUND SIDE-CHAIN CLEAVAGE SYSTEM FROM PURIFIED COMPONENTS	31	11
4143	14	9096 1994 DRUG METABOLISM AND DISPOSITION 22(6):975-978 HALL SD; HAMMAN MA; RETTIE AE; WIENKERS LC; TRAGER WF; VANDENBRANDEN M; WRIGHTON SA RELATIONSHIPS BETWEEN THE LEVELS OF CYTOCHROME P4502C9 AND ITS PROTOTYPIC CATALYTIC ACTIVITIES IN HUMAN LIVER-MICROSOMES	38	10
4144	34	7107 1990 JOURNAL OF BIOCHEMICAL TOXICOLOGY 5(2):71-90 HALLBERG E METABOLISM AND TOXICITY OF XENOBIOTICS IN THE ADRENAL-CORTEX, WITH PARTICULAR REFERENCE TO 7,12-DIMETHYLBENZ(A) ANTHRACENE	22	0
4145	4	5000 1983 TOXICOLOGY 29(1-2):49-59 HALLBERG E; RYDSTROM J METABOLISM AND TOXIC EFFECTS OF 7,12-DIMETHYLBENZ[A]ANTHRACENE IN ISOLATED RAT ADRENAL-CELLS	10	2
4146	4	8898 1994 ANNALS OF NEUROLOGY 36(6):811-813 HALLER RG OXYGEN UTILIZATION AND DELIVERY IN METABOLIC MYOPATHIES	5	2
4147	1	7654 1991 JOURNAL OF CLINICAL INVESTIGATION 88(4):1197-1206 HALLER RG; HENRIKSSON KG; JORFELDT L; HULTMAN E; WIBOM R; SAHLIN K; ARESKOG NH; GUNDER M; AYYAD K; BLOMQVIST CG; HALL RE; THUILLIER P; KENNAWAY NG; LEWIS SF DEFICIENCY OF SKELETAL-MUSCLE SUCCINATE-DEHYDROGENASE AND ACONITASE - PATHOPHYSIOLOGY OF EXERCISE IN A NOVEL HUMAN MUSCLE OXIDATIVE DEFECT	36	14
4148	1	7745 1991 NEW ENGLAND JOURNAL OF MEDICINE 324(6):364-369 HALLER RG; LEWIS SF GLUCOSE-INDUCED EXERTIONAL FATIGUE IN MUSCLE PHOSPHOFRUCTOKINASE DEFICIENCY	33	3
4149	0	6661 1989 JOURNAL OF CLINICAL INVESTIGATION 84(1):155-161 HALLER RG; LEWIS SF; ESTABROOK RW; DIMAURO S; SERVIDEI S; FOSTER DW EXERCISE INTOLERANCE, LACTIC-ACIDOSIS, AND ABNORMAL CARDIOPULMONARY REGULATION IN EXERCISE ASSOCIATED WITH ADULT SKELETAL-MUSCLE CYTOCHROME-C OXIDASE DEFICIENCY	60	60
4150	6	12696 2002 ARCHIVES OF NEUROLOGY 59(9):1395-1402 Haller RG; Vissing J Spontaneous "second wind" and glucose-induced second "second wind" in McArdle disease - Oxidative mechanisms	1	0
4151	1	6869 1990 BIOCHEMICAL PHARMACOLOGY 39(1):229-230 HALLIDAY SE; SKETT P INTERFERENCE BY META-VANADATE IN THE ASSAY FOR FORMALDEHYDE AND 4-AMINOPHENOL	5	0
4152	4	5720 1986 PHARMACOLOGY 33(5):286-291 HALPERINWALEGA ES; GREENE FE CHARACTERIZATION OF TESTOSTERONE OXIDATION BY RAT LUNG MICROSOMES	1	0
4153	2	8747 1993 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 115(1):218-223 HALPERN HJ; POU S; PERIC M; YU C; BARTH E; ROSEN GM DETECTION AND IMAGING OF OXYGEN-CENTERED FREE-RADICALS WITH LOW-FREQUENCY ELECTRON-PARAMAGNETIC RESONANCE AND SIGNAL- ENHANCING DEUTERIUM-CONTAINING SPIN TRAPS	19	1
4154	5	6084 1988 BIOCHEMICAL PHARMACOLOGY 37(15):3046-3048 HALPERT J; BALFOUR C; KAMINSKY LS EFFECT OF CHLORAMPHENICOL ADMINISTRATION INVIVO ON CYTOCHROME- P-450-DEPENDENT MONOOXYGENASE ACTIVITIES IN LIVER-MICROSOMES FROM UNINDUCED MALE-RATS	8	1
4155	7	6706 1989 MOLECULAR PHARMACOLOGY 35(1):139-147 HALPERT J; JAW JY; BALFOUR C SPECIFIC INACTIVATION BY 17-BETA-SUBSTITUTED STEROIDS OF RABBIT AND RAT-LIVER CYTOCHROMES-P-450 RESPONSIBLE FOR PROGESTERONE 21-HYDROXYLATION	0	0
4156	7	7019 1990 DRUG METABOLISM AND DISPOSITION 18(2):168-174 HALPERT J; JAW JY; BALFOUR C; KAMINSKY LS SELECTIVE INACTIVATION BY CHLOROFLUOROACETAMIDES OF THE MAJOR PHENOBARBITAL-INDUCIBLE FORM(S) OF RAT-LIVER CYTOCHROME-P-450	17	9
4157	2	6036 1988 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 264(2):462-471 HALPERT J; JAW JY; BALFOUR C; MASH EA; JOHNSON EF SELECTIVE INACTIVATION BY 21-CHLORINATED STEROIDS OF RABBIT LIVER AND ADRENAL MICROSOMAL CYTOCHROMES-P-450 INVOLVED IN PROGESTERONE HYDROXYLATION	12	11
4158	7	6554 1989 DRUG METABOLISM AND DISPOSITION 17(1):26-31 HALPERT J; JAW JY; CORNFIELD LJ; BALFOUR C; MASH EA SELECTIVE INACTIVATION OF RAT-LIVER CYTOCHROMES P-450 BY 21- CHLORINATED STEROIDS	31	15
4159	3	4966 1983 MOLECULAR PHARMACOLOGY 23(2):445-452 HALPERT J; NASLUND B; BETNER I SUICIDE INACTIVATION OF RAT-LIVER CYTOCHROME-P-450 BY CHLORAMPHENICOL INVIVO AND INVITRO	66	22
4160	6	6032 1988 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 263(1):59-68 HALPERT JR MULTIPLICITY OF STEROID-INDUCIBLE CYTOCHROMES-P-450 IN RAT- LIVER MICROSOMES	102	73
4161	63	9414 1995 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 35():29-53 HALPERT JR STRUCTURAL BASIS OF SELECTIVE CYTOCHROME-P450 INHIBITION	61	23
4162	55	9368 1994 TOXICOLOGY AND APPLIED PHARMACOLOGY 125(2):163-175 HALPERT JR; GUENGERICH FP; BEND JR; CORREIA MA SELECTIVE INHIBITORS OF CYTOCHROMES P450	185	55
4163	17	8677 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(6):4453-4457 HALPERT JR; HE YA ENGINEERING OF CYTOCHROME-P450 2B1 SPECIFICITY - CONVERSION OF AN ANDROGEN 16-BETA-HYDROXYLASE TO A 15-ALPHA-HYDROXYLASE	78	45
4164	3	6570 1989 DRUG METABOLISM REVIEWS 20(2-4):645-655 HALPERT JR; JAW JY; JOHNSON EF DESIGN OF SPECIFIC MECHANISM-BASED INACTIVATORS OF HEPATIC AND ADRENAL MICROSOMAL CYTOCHROMES-P-450 RESPONSIBLE FOR PROGESTERONE 21-HYDROXYLATION	2	2
4165	17	5438 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260(14):8397-8403 HALPERT JR; MILLER NE; GORSKY LD ON THE MECHANISM OF THE INACTIVATION OF THE MAJOR PHENOBARBITAL-INDUCIBLE ISOZYME OF RAT-LIVER CYTOCHROME-P-450 BY CHLORAMPHENICOL	67	33
4166	3	9335 1994 PHARMACOLOGY & TOXICOLOGY 75(5):255-260 HALS PA; DAHL SG EFFECT OF LEVOMEPROMAZINE AND METABOLITES ON DEBRISOQUINE HYDROXYLATION IN THE RAT	2	0
4167	20	6828 1990 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 277(1):166-180 HALVORSON M; GREENWAY D; EBERHART D; FITZGERALD K; PARKINSON A RECONSTITUTION OF TESTOSTERONE OXIDATION BY PURIFIED RAT CYTOCHROME-P450P (IIIA1)	82	45
4168	1	9053 1994 CHEMISTRY LETTERS (6):1139-1142 HAMACHI I; NOMOTO K; TANAKA S; TAJIRI Y; SHINKAI S SELF-SUFFICIENT ELECTRON INJECTION FROM NADH TO THE ACTIVE- CENTER OF FLAVIN-PENDANT MYOGLOBIN	3	0
4169	6	6495 1989 BRITISH JOURNAL OF CANCER 59(1):6-11 HAMAMOTO I; TANAKA S; MAEBA T; CHIKAISHI K; ICHIKAWA Y MICROSOMAL CYTOCHROME-P-450-LINKED MONOOXYGENASE SYSTEMS AND LIPID-COMPOSITION OF HUMAN HEPATOCELLULAR-CARCINOMA	7	2
4170	6	11585 1999 CLINICAL PHARMACOLOGY & THERAPEUTICS 66(2):110-117 Hamaoka N; Oda Y; Hase I; Mizutani K; Nakamoto T; Ishizaki T; Asada A Propofol decreases the clearance of midazolam by inhibiting CYP3A4: An in vivo and in vitro study	15	1
4171	3	8253 1992 LIPIDS 27(7):487-493 HAMBERG M; GERWICK WH; ASEN PA LINOLEIC-ACID METABOLISM IN THE RED ALGA LITHOTHAMNION- CORALLIOIDES - BIOSYNTHESIS OF 11(R)-HYDROXY-9(Z), 12(Z)- OCTADECADIENOIC ACID	29	7
4172	3	5253 1984 XENOBIOTICA 14(1-2):139-149 HAMILL S; COOPER DY THE ROLE OF CYTOCHROME-P-450 IN THE DUAL PATHWAYS OF N- DEMETHYLATION OF N,N'-DIMETHYLANILINE BY HEPATIC MICROSOMES	9	0
4173	3	4759 1983 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 224(2):614-624 HAMILL SJ; COOPER DY; SCHLEYER H; ROSENTHAL O COMPARATIVE KINETIC-STUDIES OF THE DEALKYLATION REACTION AND STEROID HYDROXYLATIONS IN VARIOUS OXYGEN AND CARBON-MONOXIDE - OXYGEN ATMOSPHERES	8	2
4174	12	4760 1983 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 224(2):625-635 HAMILL SJ; COOPER DY; SCHLEYER H; ROSENTHAL O A KINETIC-STUDY COMPARING THE LIGHT-REVERSAL PROPERTIES OF CARBON-MONOXIDE INHIBITION OF ETHYLMORPHINE, BENZPHETAMINE, AND 7-ETHOXYCOUMARIN DEALKYLATION WITH THOSE OF HYDROXYLATION OF 17-HYDROXYPROGESTERONE AND TESTOSTERONE	2	1
4175	1	1052 1969 CANADIAN JOURNAL OF MICROBIOLOGY 15(9):1021-& HAMILTON IR STUDIES WITH FLUORIDE-SENSITIVE AND FLUORIDE-RESISTANT STRAINS OF STREPTOCOCCUS SALIVARIUS .2. FLUORIDE INHIBITION OF GLUCOSE METABOLISM	18	3
4176	5	7368 1991 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 289(2):387-392 HAMILTON JW; BEMENT WJ; SINCLAIR PR; SINCLAIR JF; ALCEDO JA; WETTERHAHN KE HEME REGULATES HEPATIC 5-AMINOLEVULINATE SYNTHASE MESSENGER-RNA EXPRESSION BY DECREASING MESSENGER-RNA HALF-LIFE AND NOT BY ALTERING ITS RATE OF TRANSCRIPTION	65	5
4177	13	7876 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 298(1):96-104 HAMILTON JW; BEMENT WJ; SINCLAIR PR; SINCLAIR JF; ALCEDO JA; WETTERHAHN KE INHIBITION OF PROTEIN-SYNTHESIS INCREASES THE TRANSCRIPTION OF THE PHENOBARBITAL-INDUCIBLE CYP2H1-GENE AND CYP2H2-GENE IN CHICK-EMBRYO HEPATOCYTES	17	3
4178	3	6065 1988 BIOCHEMICAL JOURNAL 255(1):267-275 HAMILTON JW; BEMENT WJ; SINCLAIR PR; SINCLAIR JF; WETTERHAHN KE EXPRESSION OF 5-AMINOLAEVULINATE SYNTHASE AND CYTOCHROME-P-450 MESSENGER-RNAS IN CHICKEN-EMBRYO HEPATOCYTES INVIVO AND IN CULTURE - EFFECT OF PORPHYRINOGENIC DRUGS AND HEME	86	11
4179	3	1945 1972 JOURNAL OF ENDOCRINOLOGY 54(2):297-& HAMILTON MA; MCCUNE RW; ROBERTS S ACTIVATION OF SOLUBILIZED STEROID-TRANSFORMING ENZYMES OF ADRENAL MICROSOMAL ORIGIN BY SERUM-PROTEINS	11	0
4180	6	9028 1994 CANCER LETTERS 82(2):217-224 HAMILTON SM; ZHANG Z; TEEL RW EFFECTS OF ISOTHIOCYANATE ALKYL CHAIN-LENGTH ON HAMSTER LIVER CYTOCHROME-P-450 ACTIVITY	13	1
4181	1	4082 1980 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-PHYSIOLOGY 67(4):617-621 HAMMEN CS TOTAL ENERGY-METABOLISM OF MARINE BIVALVE MOLLUSKS IN ANAEROBIC AND AEROBIC STATES	25	0
4182	1	5463 1985 METHODS IN ENZYMOLOGY 111():303-311 HAMMOCK BD; MOODY DE; SEVANIAN A EPOXIDE HYDROLASES IN THE CATABOLISM OF STEROLS AND ISOPRENOIDS	15	4
4183	5	6888 1990 BIOCHEMICAL PHARMACOLOGY 40(3):637-642 HAMMOND AH; FRY JR THE INVIVO INDUCTION OF RAT HEPATIC CYTOCHROME-P450-DEPENDENT ENZYME-ACTIVITIES AND THEIR MAINTENANCE IN CULTURE	20	2
4184	5	7536 1991 DRUG METABOLISM AND DISPOSITION 19(4):804-808 HAMMOND DK; BJERCKE RJ; LANGONE JJ; STROBEL HW METABOLISM OF NICOTINE BY RAT-LIVER CYTOCHROMES-P-450 - ASSESSMENT UTILIZING MONOCLONAL-ANTIBODIES TO NICOTINE AND COTININE	20	6
4185	11	7220 1990 MOLECULAR AND CELLULAR BIOCHEMISTRY 93(2):95-105 HAMMOND DK; STROBEL HW HUMAN COLON-TUMOR CELL-LINE LS174T DRUG-METABOLIZING SYSTEM	6	2
4186	10	10910 1997 TOXICOLOGY AND APPLIED PHARMACOLOGY 145(1):54-60 Hammond DK; Zhu BT; Wang MY; Ricci MJ; Liehr JG Cytochrome P450 metabolism of estradiol in hamster liver and kidney	16	2
4187	4	1330 1970 JOURNAL OF BACTERIOLOGY 103(3):607-& HAMMOND RK; WHITE DC INHIBITION OF CAROTENOID HYDROXYLATION IN STAPHYLOCOCCUS-AUREUS BY MIXED-FUNCTION OXIDASE INHIBITORS	19	1
4188	9	6353 1989 ANALYTICAL BIOCHEMISTRY 182(2):300-303 HAMMONDS TD; BLAIR IA; FALCK JR; CAPDEVILA JH RESOLUTION OF EPOXYEICOSATRIENOATE ENANTIOMERS BY CHIRAL PHASE CHROMATOGRAPHY	43	27
4189	7	6527 1989 CHEMICAL RESEARCH IN TOXICOLOGY 2(6):367-374 HAMMONS GJ; ALWORTH WL; HOPKINS NE; GUENGERICH FP; KADLUBAR FF 2-ETHYNYLNAPHTHALENE AS A MECHANISM-BASED INACTIVATOR OF THE CYTOCHROME-P-450 CATALYZED N-OXIDATION OF 2-NAPHTHYLAMINE	36	21
4190	4	7959 1992 BIOCHIMICA ET BIOPHYSICA ACTA 1124(2):143-150 HAMPSON AJ; ROWLEY AF; BARROW SE; STEADMAN R BIOSYNTHESIS OF EICOSANOIDS BY BLOOD-CELLS OF THE CRAB, CARCINUS-MAENAS	19	1
4191	13	2095 1973 BIOCHEMICAL PHARMACOLOGY 22(3):293-310 HAMRICK ME; ZAMPAGLI.NG; STRIPP B; GILLETTE JR INVESTIGATION OF EFFECTS OF METHYLTESTOSTERONE, CORTISONE AND SPIRONOLACTONE ON HEPATIC MICROSOMAL MIXED-FUNCTION OXIDASE SYSTEM IN MALE AND FEMALE RATS	47	11
4192	13	12911 2002 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 500(1-2):103-110 Hamzeiy H; Vahdati-Mashhadian N; Edwards HJ; Goldfarb PS Mutation analysis of the human CYP3A4 gene 5 ' regulatory region: population screening using non-radioactive SSCP	2	1
4193	8	10275 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(6):2069-2075 Han IS; Choi JH Highly specific cytochrome P450-like enzymes for all-trans- retinoic acid in T47D human breast cancer cells	20	1
4194	6	11891 2000 ACTA PHARMACOLOGICA SINICA 21(8):673-679 Han XM; Zhou HH Polymorphism of CYP450 and cancer susceptibility	4	0
4195	2	4183 1980 LIFE SCIENCES 27(13):1225-1231 HANAFY MSM; BOGAN JA THE COVALENT BINDING OF 3-METHYLINDOLE METABOLITES TO BOVINE TISSUE	37	2
4196	2	1719 1972 AMERICAN JOURNAL OF PHYSIOLOGY 222(5):1071-& HANDLER JS; ORLOFF J; PRESTON AS EFFECT OF ADH, ALDOSTERONE, OUABAIN, AND AMILORIDE ON TOAD BLADDER EPITHELIAL-CELLS	101	0
4197	2	886 1968 JOURNAL OF BIOLOGICAL CHEMISTRY 243(7):1376-& HANDLER JS; PRESTON AS; ROGULSKI J CONTROL OF GLYCOGENOLYSIS IN TOADS URINARY BLADDER - EFFECT OF ANAEROBIOSIS SODIUM TRANSPORT AND ARGININE VASOTOCIN	28	1
4198	14	12118 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(18):13362-13369 Handschin C; Meyer UA A conserved nuclear receptor consensus sequence (DR-4) mediates transcriptional activation of the chicken CYP2H1 gene by phenobarbital in a hepatoma cell line	18	4
4199	9	12583 2001 MOLECULAR PHARMACOLOGY 60(4):681-689 Handschin C; Podvinec M; Looser R; Amherd R; Meyer UA Multiple enhancer units mediate drug induction of CYP2H1 by xenobiotic-sensing orphan nuclear receptor chicken xenobiotic receptor	6	2
4200	9	12228 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(20):10769-10774 Handschin C; Podvinec M; Meyer UA CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR)	22	6

#	Cited nodes	Nodes / Authors	GCS	LCS
4201	13	12576 2001 MOLECULAR ENDOCRINOLOGY 15(9):1571-1585 Handschin C; Podvinec M; Stockli J; Hoffmann K; Meyer UA Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans	11	3
4202	15	9908 1995 XENOBIOTICA 25(11):1207-1217 HANIOKA H; HAMAMURA M; KAKINO K; OGATA H; JINNO H; TAKAHASHI A; NISHIMURA T; ANDO M DOG LIVER MICROSOMAL P450 ENZYME-MEDIATED TOLUENE BIOTRANSFORMATION	1	0
4203	7	7935 1992 BIOCHEMISTRY 31(13):3364-3370 HANIOKA N; GONZALEZ FJ; LINDBERG NA; LIU G; GELBOIN HV; KORZEKWA KR SITE-DIRECTED MUTAGENESIS OF CYTOCHROME-P450S CYP2A1 AND CYP2A2 - INFLUENCE OF THE DISTAL HELIX ON THE KINETICS OF TESTOSTERONE HYDROXYLATION	30	17
4204	11	8240 1992 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 43(8):1037-1043 HANIOKA N; GONZALEZ FJ; LINDBERG NA; LIU G; KORZEKWA KR CHIMERIC CDNA EXPRESSION AND SITE DIRECTED MUTAGENESIS STUDIES OF CYTOCHROME-P450S CYP2A1 AND CYP2A2	5	3
4205	11	11929 2000 ARCHIVES OF TOXICOLOGY 73(12):625-631 Hanioka N; Jinno H; Chung YS; Nishimura T; Tanaka-Kagawa T; Ando M Effect of 4-tert-octylphenol on cytochrome P450 enzymes in rat liver	3	1
4206	6	11884 1999 XENOBIOTICA 29(9):873-883 Hanioka N; Jinno H; Chung YS; Tanaka-Kagawa T; Nishimura T; Ando M Inhibition of rat hepatic cytochrome P450 activities by biodegradation products of 4-tert-octylphenol ethoxylate	7	1
4207	12	11118 1998 CHEMICO-BIOLOGICAL INTERACTIONS 116(3):181-198 Hanioka N; Jinno H; Kitazawa K; Tanaka-Kagawa T; Nishimura T; Ando M; Ogawa K In vitro biotransformation of atrazine by rat liver microsomal cytochrome P450 enzymes	11	2
4208	11	11887 1999 XENOBIOTICA 29(12):1213-1226 Hanioka N; Jinno H; Tanaka-Kagawa T; Nishimura T; Ando M In vitro metabolism of simazine, atrazine and propazine by hepatic cytochrome P450 enzymes of rat, mouse and guinea pig, and oestrogenic activity of chlorotriazines and their main metabolites	4	0
4209	7	12003 2000 CHEMOSPHERE 41(7):973-978 Hanioka N; Jinno H; Tanaka-Kagawa T; Nishimura T; Ando M Interaction of bisphenol A with rat hepatic cytochrome P450 enzymes	5	1
4210	6	6806 1990 AMERICAN JOURNAL OF HUMAN GENETICS 47(6):994-1001 HANIOKA N; KIMURA S; MEYER UA; GONZALEZ FJ THE HUMAN CYP2D LOCUS ASSOCIATED WITH A COMMON GENETIC-DEFECT IN DRUG OXIDATION - A G1934-]A BASE CHANGE IN INTRON-3 OF A MUTANT CYP2D6 ALLELE RESULTS IN AN ABERRANT-3' SPLICE RECOGNITION SITE	96	24
4211	7	7285 1990 PROTEIN ENGINEERING 3(7):571-575 HANIOKA N; KORZEKWA K; GONZALEZ FJ SEQUENCE REQUIREMENTS FOR CYTOCHROMES P450IIA1 AND P450IIA2 CATALYTIC ACTIVITY - EVIDENCE FOR BOTH SPECIFIC AND NONSPECIFIC SUBSTRATE BINDING INTERACTIONS THROUGH USE OF CHIMERIC CDNAS AND CDNA EXPRESSION	18	12
4212	8	12776 2002 DRUG METABOLISM AND DISPOSITION 30(4):391-396 Hanioka N; Ozawa S; Jinno H; Tanaka-Kagawa T; Nishimura T; Ando M; Sawada JI Interaction of irinotecan (CPT-11) and its active metabolite 7- ethyl-10-hydroxycamptothecin (SN-38) with human cytochrome P450 enzymes	0	0
4213	9	13120 2003 XENOBIOTICA 33(6):575-586 Hanioka N; Tanaka-Kagawa T; Miyata Y; Matsushima E; Makino Y; Ohno A; Yoda R; Jinno H; Ando M Functional characterization of three human cytochrome P450 2E1 variants with amino acid substitutions	0	0
4214	3	12134 2000 JOURNAL OF CHROMATOGRAPHY B 744(2):399-406 Hanioka N; Tatarazako N; Jinno H; Arizono K; Ando M Determination of cytochrome P450 1A activities in mammalian liver microsomes by high-performance liquid chromatography with fluorescence detection	5	1
4215	21	12330 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 393(2):255-261 Hanna IH; Kim MS; Guengerich FP Heterologous expression of cytochrome P450 2D6 mutants, electron transfer, and catalysis of bufuralol hydroxylation: The role of aspartate 301 in structural integrity	13	7
4216	31	12528 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(43):39553-39561 Hanna IH; Krauser JA; Cai HL; Kim MS; Guengerich FP Diversity in mechanisms of substrate oxidation by cytochrome P450 2D6 - Lack of an allosteric role of nadph-cytochrome P450 reductase in catalytic regioselectivity	5	4
4217	16	11038 1998 BIOCHEMISTRY 37(1):311-318 Hanna IH; Roberts ES; Hollenberg PF Molecular basis for the differences in lidocaine binding and regioselectivity of oxidation by cytochromes P450 2B1 and 2B2	6	2
4218	23	10970 1998 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 350(2):324-332 Hanna IH; Teiber JF; Kokones KL; Hollenberg PF Role of the alanine at position 363 of cytochrome P450 2B2 in influencing the NADPH- and hydroperoxide-supported activities	46	26
4219	1	10947 1998 AMERICAN JOURNAL OF HUMAN GENETICS 63(1):29-36 Hanna MG; Nelson IP; Rahman S; Lane RJM; Land J; Heales S; Cooper MJ; Schapira AHV; Morgan-Hughes JA; Wood NW Cytochrome c oxidase deficiency associated with the first stop- codon point mutation in human mtDNA	44	1
4220	16	12487 2001 FOOD AND CHEMICAL TOXICOLOGY 39(2):125-132 Hannon-Fletcher MPA; O'Kane MJ; Moles KW; Barnett YA; Barnett CR Lymphocyte cytochrome P450-CYP2E1 expression in human IDDM subjects	6	0
4221	3	3088 1976 EXPERIENTIA 32(10):1246-1249 HANOZET GM; SIMONETTA M; BARISIO D; GUERRITORE A REGULATION OF ENZYMES OF ETHANOL-METABOLISM IN YEAST (RHODOTORULA-GRACILIS)	6	1
4222	5	7286 1990 QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS 9(3):223-226 HANSCH C; SINCLAIR JF; SINCLAIR PR INDUCTION OF CYTOCHROME-P450 BY BARBITURATES IN CHICK-EMBRYO HEPATOCYTES - A QUANTITATIVE STRUCTURE-ACTIVITY ANALYSIS	14	6
4223	14	8597 1993 DRUG METABOLISM REVIEWS 25(1-2):1-48 HANSCH C; ZHANG LT QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS OF CYTOCHROME-P- 450	31	5
4224	6	6548 1989 DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY 8(3):179-191 HANSEN AJ; MAY BK SEQUENCE OF A CHICKEN PHENOBARBITAL-INDUCIBLE CYTOCHROME-P450 CDNA - REGULATION OF 2 P450 MESSENGER-RNAS TRANSCRIBED FROM DIFFERENT GENES	44	20
4225	20	1517 1971 BIOCHEMICAL PHARMACOLOGY 20(11):3125-& HANSEN AR; FOUTS JR COMPARISON OF EFFECTS OF BENZPYRENE ADMINISTRATION ON SOME HEPATIC MICROSOMAL MIXED-FUNCITION OXIDASES OF RATS AND MICE	25	9
4226	7	1559 1971 CHEMICO-BIOLOGICAL INTERACTIONS 3(2):123-& HANSEN AR; FOUTS JR STUDIES ON SHIFT IN PH OPTIMUM OF HEPATIC MICROSOMAL ANILINE PARA-HYDROXYLATION FOLLOWING TREATMENT OF RATS WITH 3,4- BENZPYRENE	6	0
4227	1	7675 1991 JOURNAL OF PHARMACEUTICAL SCIENCES 80(8):793-798 HANSEN KT; FAARUP P; BUNDGAARD H CARBAMATE ESTER PRODRUGS OF DOPAMINERGIC COMPOUNDS - SYNTHESIS, STABILITY, AND BIOCONVERSION	16	0
4228	3	1503 1971 BIOCHEMICAL PHARMACOLOGY 20(7):1569-& HANSEN LG; HODGSON E BIOCHEMICAL CHARACTERISTICS OF INSECT MICROSOMES - N- DEMETHYLATION AND O-DEMETHYLATION	82	6
4229	4	2532 1974 GENERAL PHARMACOLOGY 5(2):157-163 HANSEN LG; METCALF RL; KAPOOR IP BIOCHEMISTRY OF SELECTIVE TOXICITY AND BIODEGRADABILITY .2. COMPARATIVE INVIVO AND MICROSOMAL O-DEALKYLATION BY MICE AND FLIES	0	1
4230	9	6702 1989 MOLECULAR CARCINOGENESIS 2(5):261-267 HANSEN SK; ROSS JA; SIEGFRIED JM; LEAVITT S; RUDO K; LANGENBACH R; NESNOW S TRANSFECTION OF A RAT CYTOCHROME P450B CDNA INTO C3H10T1/2CL8 MOUSE EMBRYO FIBROBLASTS	10	5
4231	3	3574 1978 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 59(1):37-46 HANSFORD RG COMPARISON OF ENERGY-YIELDING REACTIONS IN FLIGHT-MUSCLE OF YOUNG-ADULT AND SENESCENT BLOWFLIES	10	1
4232	12	4808 1983 BIOCHIMICA ET BIOPHYSICA ACTA 726(1):41-80 HANSFORD RG BIOENERGETICS IN AGING	160	0
4233	11	7614 1991 JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 23(6):823-854 HANSFORD RG DEHYDROGENASE ACTIVATION BY CA2+ IN CELLS AND TISSUES	93	3
4234	4	2081 1973 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 51(2):480-486 HANSFORD RG; LEHNINGE.AL ACTIVE OXIDATIVE DECARBOXYLATION OF MALATE BY MITOCHONDRIA ISOLATED FROM L-1210 ASCITES TUMOR-CELLS	25	7
4235	3	1305 1970 FEBS LETTERS 7(2):183-& HANSFORD RG; SACKTOR B REGULATION OF GLYCOGEN METABOLISM IN INSECT FLIGHT MUSCLE ACTIVATION OF PHOSPHORYLASE-B-KINASE BY CALCIUM AND INORGANIC PHOSPHATE	23	1
4236	5	604 1967 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 27(6):686-& HANSFORD.RG; CHAPPELL JB EFFECT OF CA2+ ON OXIDATION OF GLYCEROL PHOSPHOSPHATE BY BLOWFLY FLIGHT-MUSCLE MITOCHONDRIA	100	0
4237	8	3025 1976 BIOCHIMICA ET BIOPHYSICA ACTA 456(2):129-148 HANSTEIN WG UNCOUPLING OF OXIDATIVE-PHOSPHORYLATION	174	2
4238	2	3210 1976 TRENDS IN BIOCHEMICAL SCIENCES 1(3):65-67 HANSTEIN WG UNCOUPLING OF OXIDATIVE-PHOSPHORYLATION	28	0
4239	4	2401 1974 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 163(2):482-490 HANSTEIN WG; DAVIS KA; HATEFI Y SOLVENT ISOTOPE-EFFECTS ON STRUCTURE AND FUNCTION OF MITOCHONDRIAL-MEMBRANES IN AQUEOUS-MEDIA	20	1
4240	54	8234 1992 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 43(8):779-804 HANUKOGLU I STEROIDOGENIC ENZYMES - STRUCTURE, FUNCTION, AND ROLE IN REGULATION OF STEROID-HORMONE BIOSYNTHESIS	121	21
4241	16	7149 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(33):20602-20608 HANUKOGLU I; FEUCHTWANGER R; HANUKOGLU A MECHANISM OF CORTICOTROPIN AND CAMP INDUCTION OF MITOCHONDRIAL CYTOCHROME-P450 SYSTEM ENZYMES IN ADRENAL-CORTEX CELLS	46	8
4242	8	6582 1989 EUROPEAN JOURNAL OF BIOCHEMISTRY 180(2):479-484 HANUKOGLU I; GUTFINGER T CDNA SEQUENCE OF ADRENODOXIN REDUCTASE - IDENTIFICATION OF NADP-BINDING SITES IN OXIDOREDUCTASES	134	16
4243	20	5648 1986 EUROPEAN JOURNAL OF BIOCHEMISTRY 157(1):27-31 HANUKOGLU I; HANUKOGLU Z STOICHIOMETRY OF MITOCHONDRIAL CYTOCHROMES-P-450, ADRENODOXIN AND ADRENODOXIN REDUCTASE IN ADRENAL-CORTEX AND CORPUS-LUTEUM - IMPLICATIONS FOR MEMBRANE ORGANIZATION AND GENE-REGULATION	52	11
4244	14	4136 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(7):3057-3061 HANUKOGLU I; JEFCOATE CR MITOCHONDRIAL CYTOCHROME-P-450SCC - MECHANISM OF ELECTRON- TRANSPORT BY ADRENODOXIN	91	28
4245	14	4389 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256(9):4329-4335 HANUKOGLU I; PRIVALLE CT; JEFCOATE CR MECHANISMS OF IONIC ACTIVATION OF ADRENAL MITOCHONDRIAL CYTOCHROME-P-450SCC AND CYTOCHROME-P450(11-BETA)	46	14
4246	13	9638 1995 ENDOCRINE RESEARCH 21(1-2):231-241 HANUKOGLU I; RAPOPORT R ROUTES AND REGULATION OF NADPH PRODUCTION IN STEROIDOGENIC MITOCHONDRIA	2	0
4247	3	3524 1978 BIOCHEMICAL PHARMACOLOGY 27(10):1441-1444 HANZLIK RP; SHEARER GO SECONDARY DEUTERIUM-ISOTOPE EFFECTS ON OLEFIN EPOXIDATION BY CYTOCHROME-P-450	41	3
4248	1	5409 1985 IRCS MEDICAL SCIENCE-BIOCHEMISTRY 13(1):32-33 HAQUE SJ; PODDAR MK INTERACTION OF DELTA-9-TETRAHYDROCANNABINOL AND BIOLOGICAL- MEMBRANES USING 1-ANILINO-8-NAPHTHALENE SULFONATE AS A FLUORESCENCE PROBE	0	0
4249	15	12179 2000 MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS 12(1-2):103-109 Hara M Application of P450s for biosensing: combination of biotechnology and electrochemistry	3	2
4250	13	11544 1999 BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 63(1):21-28 Hara M; Miyake J; Asada Y; Ohkawa H Purified fusion enzyme between rat cytochrome P4501A1 and yeast NADPH-cytochrome P450 oxidoreductase	3	3
4251	3	10774 1997 JOURNAL OF FERMENTATION AND BIOENGINEERING 84(4):324-329 Hara M; Ohkawa H; Narato M; Shirai M; Asada Y; Karube I; Miyake J Regeneration of NADPH by cactus chloroplasts: Coupling reaction with P450 monooxygenase	3	1
4252	3	9868 1995 PROSTAGLANDINS AND RELATED COMPOUNDS 23():121-123 HARA S; MIYATA A; YOKOYAMA C; BRUGGER R; LOTTSPEICH F; ULLRICH V; TANABE T MOLECULAR-CLONING AND EXPRESSION OF PROSTACYCLIN SYNTHASE FROM ENDOTHELIAL-CELLS	3	2
4253	6	9200 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(31):19897-19903 HARA S; MIYATA A; YOKOYAMA C; INOUE H; BRUGGER R; LOTTSPEICH F; ULLRICH V; TANABE T ISOLATION AND MOLECULAR-CLONING OF PROSTACYCLIN SYNTHASE FROM BOVINE ENDOTHELIAL-CELLS	57	11
4254	15	7610 1991 JOURNAL OF BIOCHEMISTRY 110(2):261-266 HARA T; MIYATA T IDENTIFICATION OF A CROSS-LINKED PEPTIDE OF A COVALENT COMPLEX BETWEEN ADRENODOXIN REDUCTASE AND ADRENODOXIN	10	1
4255	2	6057 1988 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 156(2):725-732 HARADA N CLONING OF A COMPLETE CDNA-ENCODING HUMAN AROMATASE - IMMUNOCHEMICAL IDENTIFICATION AND SEQUENCE-ANALYSIS	132	30
4256	2	7827 1992 AMERICAN JOURNAL OF HUMAN GENETICS 51(3):666-672 HARADA N; OGAWA H; SHOZU M; YAMADA K GENETIC-STUDIES TO CHARACTERIZE THE ORIGIN OF THE MUTATION IN PLACENTAL AROMATASE DEFICIENCY	26	8
4257	13	4125 1980 JOURNAL OF BIOCHEMISTRY 87(5):1539-1554 HARADA N; OMURA T PARTICIPATION OF CYTOCHROME-P-450 IN THE REDUCTION OF NITRO- COMPOUNDS BY RAT-LIVER MICROSOMES	77	10
4258	12	4374 1981 JOURNAL OF BIOCHEMISTRY 89(1):237-248 HARADA N; OMURA T SELECTIVE INDUCTION OF 2 DIFFERENT MOLECULAR-SPECIES OF CYTOCHROME-P-450 BY PHENOBARBITAL AND 3-METHYLCHOLANTHRENE	146	22
4259	4	11071 1998 BIOORGANIC & MEDICINAL CHEMISTRY 6(3):339-347 Haraguchi H; Ishikawa H; Mizutani K; Tamura Y; Kinoshita T Antioxidative and superoxide scavenging activities of retrochalcones in Glycyrrhiza inflata	12	0
4260	4	10586 1997 BIOORGANIC & MEDICINAL CHEMISTRY 5(5):865-871 Haraguchi H; Ishikawa H; Sanchez Y; Ogura T; Kubo Y; Kubo I Antioxidative constituents in Heterotheca inuloides	6	1
4261	3	10523 1997 ARCHIVES OF MICROBIOLOGY 167(1):6-10 Haraguchi H; Yokoyama K; Oike S; Ito M; Nozaki H Respiratory stimulation and generation of superoxide radicals in Pseudomonas aeruginosa by fungal naphthoquinones	2	0
4262	4	5070 1984 BIOCHEMISTRY INTERNATIONAL 8(1):49-59 HARATA J; NAGATA M; ISHIGURO I; OHTA Y EFFECT OF 2-MERCAPTOPROPIONYLGLYCINE ON LIPID-PEROXIDATION AND DRUG OXIDATION IN RAT-LIVER MICROSOMES	2	0
4263	14	7842 1992 ANNUAL REVIEW OF MICROBIOLOGY 46():565-601 HARAYAMA S; KOK M; NEIDLE EL FUNCTIONAL AND EVOLUTIONARY RELATIONSHIPS AMONG DIVERSE OXYGENASES	196	5
4264	8	11399 1998 STROKE 29(1):229-234 Harder DR; Alkayed NJ; Lange AR; Gebremedhin D; Roman RJ Functional hyperemia in the brain - Hypothesis for astrocyte- derived vasodilator metabolites	34	6
4265	30	9793 1995 JOURNAL OF VASCULAR RESEARCH 32(2):79-92 HARDER DR; CAMPBELL WB; ROMAN RJ ROLE OF CYTOCHROME-P-450 ENZYMES AND METABOLITES OF ARACHIDONIC-ACID IN THE CONTROL OF VASCULAR TONE	166	45
4266	11	8889 1994 AMERICAN JOURNAL OF PHYSIOLOGY 266(5):H2098-H2107 HARDER DR; GEBREMEDHIN D; NARAYANAN J; JEFCOAT C; FALCK JR; CAMPBELL WB; ROMAN R FORMATION AND ACTION OF A P-450 4A METABOLITE OF ARACHIDONIC- ACID IN CAT CEREBRAL MICROVESSELS	87	13
4267	6	10111 1996 CIRCULATION RESEARCH 79(1):54-61 Harder DR; Narayanan J; Birks EK; Liard JF; Imig JD; Lombard JH; Lange AR; Roman RJ Identification of a putative microvascular oxygen sensor	69	6
4268	6	11892 2000 ACTA PHYSIOLOGICA SCANDINAVICA 168(4):543-549 Harder DR; Roman RJ; Gebremedhin D Molecular mechanisms controlling nutritive blood flow: role of cytochrome P450 enzymes	6	1
4269	2	7717 1991 MOLECULAR & GENERAL GENETICS 227(2):238-244 HARDER PA; OKEEFE DP; ROMESSER JA; LETO KJ; OMER CA ISOLATION AND CHARACTERIZATION OF STREPTOMYCES-GRISEOLUS DELETION MUTANTS AFFECTED IN CYTOCHROME-P-450-MEDIATED HERBICIDE METABOLISM	9	3
4270	6	535 1966 JOURNAL OF BIOLOGICAL CHEMISTRY 241(10):2212-& HARDING BW; NELSON DH ELECTRON CARRIERS OF BOVINE ADRENAL CORTICAL RESPIRATORY CHAIN AND HYDROXYLATING PATHWAYS	68	54
4271	5	441 1965 STEROIDS S():51-& HARDING BW; WILSON LD; WONG SH; NELSON DH ELECTRON CARRIERS OF RAT ADRENAL AND 11BETA-HYDROXYLATING SYSTEM	0	0
4272	1	306 1964 BIOCHIMICA ET BIOPHYSICA ACTA 92(2):415-& HARDING BW; WONG SH; NELSON DH CARBON MONOXIDE-COMBINING SUBSTANCES IN RAT ADRENAL	103	81
4273	16	5910 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262(2):801-810 HARDWICK JP; SONG BJ; HUBERMAN E; GONZALEZ FJ ISOLATION, COMPLEMENTARY-DNA SEQUENCE, AND REGULATION OF RAT HEPATIC LAURIC ACID OMEGA-HYDROXYLASE (CYTOCHROME-P-450LA- OMEGA) - IDENTIFICATION OF A NEW CYTOCHROME-P-450 GENE FAMILY	304	151
4274	6	5407 1985 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 17(4):455-462 HARE WR; WAHLE KWJ THE EFFECTS OF PHYSIOLOGICAL-STATE AND PLANE OF NUTRITION ON THE CONCENTRATIONS OF MICROSOMAL CYTOCHROMES AND THE OMEGA- OXIDATION OF FATTY-ACIDS IN VARIOUS TISSUES OF THE SHEEP (OVIS- ARIES)	3	0
4275	5	10200 1996 FEMS MICROBIOLOGY LETTERS 139(2-3):203-207 Hargreaves JA; Keon JPR Isolation of an Ustilago maydis ERG11 gene and its expression in a mutant deficient in sterol 14 alpha-demethylase activity	13	5
4276	13	8584 1993 DNA AND CELL BIOLOGY 12(5):371-379 HARIKRISHNA JA; BLACK SM; SZKLARZ GD; MILLER WL CONSTRUCTION AND FUNCTION OF FUSION ENZYMES OF THE HUMAN CYTOCHROME-P450SCC SYSTEM	57	16
4277	23	9945 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 326(1):85-92 Harlow GR; Halpert JR Mutagenesis study of Asp-290 in cytochrome P450 2B11 using a fusion protein with rat NADPH-cytochrome P450 reductase	18	9
4278	17	10579 1997 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1338(2):259-266 Harlow GR; He YA; Halpert JR Functional interaction between amino-acid residues 242 and 290 in cytochromes P-450 2B1 and 2B11	12	3
4279	4	4321 1981 BRITISH JOURNAL OF INDUSTRIAL MEDICINE 38(1):91-97 HARMAN AW; FREWIN DB; PRIESTLY BG INDUCTION OF MICROSOMAL DRUG-METABOLISM IN MAN AND IN THE RAT BY EXPOSURE TO PETROLEUM	14	1
4280	2	556 1966 NATURE 209(5019):174-& HARMEY MA; IKUMA H; BONNER WD NEAR ULTRA-VIOLET SPECTRUM OF WHITE POTATO MITOCHONDRIA	7	4
4281	5	2088 1973 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 55(1):169-173 HARMON HJ; CRANE FL TOPOGRAPHY OF CRISTAE MEMBRANE AS ELUCIDATED BY A NEW INHIBITOR, TRIFLUOROFURYLBUTANEDIONE	16	4
4282	12	2460 1974 BIOCHIMICA ET BIOPHYSICA ACTA 344(2):119-155 HARMON HJ; HALL JD; CRANE FL STRUCTURE OF MITOCHONDRIAL CRISTAE MEMBRANES	104	6
4283	14	7325 1990 XENOBIOTICA 20(10):1053-1063 HARMSWORTH WL; FRANKLIN MR INDUCTION OF HEPATIC AND EXTRAHEPATIC CYTOCHROME-P-450 AND MONOOXYGENASE ACTIVITIES BY N-SUBSTITUTED IMIDAZOLES	12	5
4284	1	6131 1988 BIOMEDICAL AND ENVIRONMENTAL MASS SPECTROMETRY 15(11):615-621 HAROLDSEN PE; REILLY MH; HUGHES H; GASKELL SJ; PORTER CJ CHARACTERIZATION OF GLUTATHIONE CONJUGATES BY FAST ATOM BOMBARDMENT TANDEM MASS-SPECTROMETRY	45	4
4285	7	8278 1992 MOLECULAR PHARMACOLOGY 42(4):603-612 HARPER PA; GIANNONE JV; OKEY AB; DENISON MS INVITRO TRANSFORMATION OF THE HUMAN AH RECEPTOR AND ITS BINDING TO A DIOXIN RESPONSE ELEMENT	25	4
4286	5	6142 1988 CANCER RESEARCH 48(9):2388-2395 HARPER PA; GOLAS CL; OKEY AB CHARACTERIZATION OF THE AH RECEPTOR AND ARYL-HYDROCARBON HYDROXYLASE INDUCTION BY 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN AND BENZ(A)ANTHRACENE IN THE HUMAN A431 SQUAMOUS-CELL CARCINOMA LINE	59	7
4287	2	10690 1997 EUROPEAN HEART JOURNAL 18(12):1865-1872 Harrington D; Coats AJS Skeletal muscle abnormalities and evidence for their role in symptom generation in chronic heart failure	19	0
4288	2	7026 1990 DRUG METABOLISM AND DISPOSITION 18(5):626-631 HARRINGTON GW; MAGEE PN; PYLYPIW HM; KOZENIAUSKAS R; BEVILL RF; NELSON DR; THURMON JC THE FORMATION, DISPOSITION, AND HEPATIC-METABOLISM OF DIMETHYLNITROSAMINE IN THE PIG	5	0
4289	10	7484 1991 CANCER RESEARCH 51(18):S5023-S5044 HARRIS CC CHEMICAL AND PHYSICAL CARCINOGENESIS - ADVANCES AND PERSPECTIVES FOR THE 1990S	408	0
4290	1	8748 1993 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 115(19):8775-8779 HARRIS D; LOEW G DETERMINANTS OF THE SPIN-STATE OF THE RESTING STATE OF CYTOCHROME-P450CAM	41	5
4291	2	1003 1969 BIOCHEMICAL JOURNAL 115(4):645-& HARRIS EJ; BERENT C CALCIUM ION-INDUCED UPTAKES AND TRANSFORMATIONS OF SUBSTRATES IN LIVER MITOCHONDRIA	26	1
4292	6	633 1967 BIOCHEMISTRY 6(5):1348-& HARRIS EJ; HOFER MP; PRESSMAN BC STIMULATION OF MITOCHONDRIAL RESPIRATION AND PHOSPHORYLATION BY TRANSPORT-INDUCING ANTIBIOTICS	97	10
4293	1	786 1968 BIOCHEMICAL JOURNAL 109(2):239-& HARRIS EJ; MANGER JR INTRAMITOCHRONDRIAL SUBSTRATE CONCENTRATION AS A FACTOR CONTROLLING METABOLISM	51	0
4294	1	3499 1978 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 82(3):982-989 HARRIS JS; VANTASSEL E; CHANEY SG MUTATION IN ESCHERICHIA-COLI THAT MIMICS DIAUXIE LAG	2	0
4295	1	1765 1972 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 46(5):1743-& HARRIS JW; BIAGLOW JE NONSPECIFIC REACTIONS OF GLUTATHIONE OXIDANT DIAMIDE WITH MAMMALIAN-CELLS	87	0
4296	16	7155 1990 JOURNAL OF CELLULAR PHYSIOLOGY 144(3):429-437 HARRIS RC; HOMMA T; JACOBSON HR; CAPDEVILA J EPOXYEICOSATRIENOIC ACIDS ACTIVATE NA+/H+ EXCHANGE AND ARE MITOGENIC IN CULTURED RAT GLOMERULAR MESANGIAL CELLS	67	28
4297	8	7069 1990 FASEB JOURNAL 4(6):1654-1660 HARRIS RC; MUNGER KA; BADR KF; TAKAHASHI K MEDIATION OF RENAL VASCULAR EFFECTS OF EPIDERMAL GROWTH-FACTOR BY ARACHIDONATE METABOLITES	18	2
4298	4	1359 1970 JOURNAL OF CELL BIOLOGY 45(3):514-& HARRISON DE UNDAMPED OSCILLATIONS OF PYRIDINE NUCLEOTIDE AND OXYGEN TENSION IN CHEMOSTAT CULTURES OF KLEBSIELLA-AEROGENES	10	0
4299	4	1192 1970 APPLIED MICROBIOLOGY 19(3):446-& HARRISON DE; CHANCE B FLUORIMETRIC TECHNIQUE FOR MONITORING CHANGES IN LEVEL OF REDUCED NICOTINAMIDE NUCLEOTIDES IN CONTINUOUS CULTURES OF MICROORGANISMS	72	0
4300	5	995 1969 BIOCHEMICAL JOURNAL 112(5):647-& HARRISON DE; MAITRA PK CONTROL OF RESPIRATION AND METABOLISM IN GROWIG KLEBSIELLA AEROGENES - ROLE OF ADENINE NUCLEOTIDES	106	0

#	Cited nodes	Nodes / Authors	GCS	LCS
4301	2	9768 1995 JOURNAL OF PATHOLOGY 175(1):7-12 HARRISON DJ MOLECULAR MECHANISMS OF DRUG-RESISTANCE IN TUMORS	52	0
4302	2	8428 1993 BAILLIERES CLINICAL GASTROENTEROLOGY 7(3):641-662 HARRISON DJ; BURT AD PATHOLOGY OF ALCOHOLIC LIVER-DISEASE	6	0
4303	1	6249 1988 JOURNAL OF ETHNOPHARMACOLOGY 23(1):61-71 HART LA; VANENCKEVORT PH; VANDIJK H; ZAAT R; DESILVA KTD; LABADIE RP 2 FUNCTIONALLY AND CHEMICALLY DISTINCT IMMUNOMODULATORY COMPOUNDS IN THE GEL OF ALOE-VERA	10	0
4304	2	1698 1971 STEROIDS 17(5):575-& HART MH; SWACKHAM.ES; STRAW JA STUDIES ON SITE OF ACTION OF ORTHO,PARA'-DDD IN DOG ADRENAL CORTEX .2. TPNH- AND CORTICOSTEROID PRECURSOR-STIMULATION OF ORTHO,PARA'-DDD INHIBITED STEROIDOGENESIS	35	0
4305	2	1505 1971 BIOCHEMICAL PHARMACOLOGY 20(7):1689-& HART MM; STRAW JA EFFECT OF 1-(ORTHO-CHLOROPHENYL)-1-(PARA-CHLOROPHENYL)-2,2- DICHLOROETHANE IN-VIVO ON BASELINE AND ADRENOCORTICOTROPIC HORMONE-INDUCED STEROID PRODUCTION IN DOG ADRENAL SLICES	5	0
4306	7	3263 1977 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 77(3):953-958 HARTLE DK; KAPKE GF; BARON J ALTERATIONS IN CONTENTS OF CYTOCHROME-P-450 AND ADRENAL FERREDOXIN IN ADRENALS OF SPONTANEOUSLY HYPERTENSIVE RATS	1	0
4307	9	10640 1997 CURRENT PHARMACEUTICAL DESIGN 3(2):177-208 Hartman PG; Sanglard D Inhibitors of ergosterol biosynthesis as antifungal agents	11	0
4308	8	12147 2000 JOURNAL OF MEDICINAL CHEMISTRY 43(23):4437-4445 Hartmann RW; Hector M; Wachall BG; Palusczak A; Palzer M; Huch V; Veith M Synthesis and evaluation of 17-aliphatic heterocycle- substituted steroidal inhibitors of 17 alpha-hydroxylase/C17- 20-lyase (P450 17)	10	2
4309	35	10288 1996 JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 16(4):273-285 Harvey AT; Preskorn SH Cytochrome p450 enzymes: Interpretation of their interactions with selective serotonin reuptake inhibitors .1.	57	12
4310	14	12037 2000 DRUG METABOLISM AND DISPOSITION 28(1):96-101 Harvey JL; Paine AJ; Maurel P; Wright MC Effect of the adrenal 11-beta-hydroxylase inhibitor metyrapone on human hepatic cytochrome P-450 expression: Induction of cytochrome Pp-450 3A4	4	2
4311	14	11023 1998 BIOCHEMICAL JOURNAL 331():273-281 Harvey JL; Paine AJ; Wright MC Disruption of endogenous regulator homeostasis underlies the mechanism of rat CYP1A1 mRNA induction by metyrapone	8	3
4312	8	4869 1983 FEBS LETTERS 155(2):257-262 HASEGAWA T THE RECOGNITION OF A SOLUBLE CYTOCHROME-P450 IN RAT-LIVER	0	0
4313	37	9878 1995 STRUCTURE 3(1):41-62 HASEMANN CA; KURUMBAIL RG; BODDUPALLI SS; PETERSON JA; DEISENHOFER J STRUCTURE AND FUNCTION OF CYTOCHROMES-P450 - A COMPARATIVE- ANALYSIS OF 3 CRYSTAL-STRUCTURES	191	82
4314	20	9558 1995 CANCER RESEARCH 55(4):787-791 HASHIMOTO H; NAKAGAWA T; YOKOI T; SAWADA M; ITOH S; KAMATAKI T FETUS-SPECIFIC CYP3A7 AND ADULT-SPECIFIC CYP3A4 EXPRESSED IN CHINESE-HAMSTER CHL CELLS HAVE SIMILAR CAPACITY TO ACTIVATE CARCINOGENIC MYCOTOXINS	22	11
4315	19	8618 1993 EUROPEAN JOURNAL OF BIOCHEMISTRY 218(2):585-595 HASHIMOTO H; TOIDE K; KITAMURA R; FUJITA M; TAGAWA S; ITOH S; KAMATAKI T GENE STRUCTURE OF CYP3A4, AN ADULT-SPECIFIC FORM OF CYTOCHROME- P450 IN HUMAN LIVERS, AND ITS TRANSCRIPTIONAL CONTROL	102	51
4316	12	9446 1995 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 320(2):323-329 HASHIMOTO H; YANAGAWA Y; SAWADA M; ITOH S; DEGUCHI T; KAMATAKI T SIMULTANEOUS EXPRESSION OF HUMAN CYP3A7 AND N-ACETYLTRANSFERASE IN CHINESE-HAMSTER CHL CELLS RESULTS IN HIGH CYTOTOXICITY FOR CARCINOGENIC HETEROCYCLIC AMINES	7	5
4317	6	6597 1989 FEBS LETTERS 248(1-2):205-209 HASHIMOTO S; NAKAJIMA R; YAMAZAKI I; KOTANI T; OHTAKI S; KITAGAWA T RESONANCE RAMAN CHARACTERIZATION OF HOG THYROID PEROXIDASE - AN SERRS STUDY	6	0
4318	4	8152 1992 JOURNAL OF BIOCHEMISTRY 112(5):573-575 HASHIMOTO T; MOROHASHI K; TAKAYAMA K; HONDA S; WADA T; HANDA H; OMURA T COOPERATIVE TRANSCRIPTION ACTIVATION BETWEEN AD1, A CRE-LIKE ELEMENT, AND OTHER ELEMENTS IN THE CYP11B GENE PROMOTER	20	7
4319	5	6625 1989 JOURNAL OF BIOCHEMISTRY 105(5):676-679 HASHIMOTO T; MOROHASHI KI; OMURA T CLONING AND CHARACTERIZATION OF BOVINE CYTOCHROME P-450(11- BETA) GENES	34	13
4320	5	8901 1994 ANNUAL REVIEW OF PLANT PHYSIOLOGY AND PLANT MOLECULAR BIOLOGY 45():257-285 HASHIMOTO T; YAMADA Y ALKALOID BIOGENESIS - MOLECULAR ASPECTS	50	1
4321	17	4126 1980 JOURNAL OF BIOCHEMISTRY 88(2):505-516 HASHIMOTOYUTSUDO C; IMAI Y; SATO R MULTIPLE FORMS OF CYTOCHROME-P-450 PURIFIED FROM LIVER- MICROSOMES OF PHENOBARBITAL-PRETREATED AND 3- METHYLCHOLANTHRENE-PRETREATED RABBITS .2. SPECTRAL PROPERTIES	47	0
4322	13	12882 2002 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 300(1):298-304 Hashizume T; Imaoka S; Mise M; Terauchi Y; Fujii T; Miyazaki H; Kamataki T; Funae Y Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal Microsomes	3	1
4323	14	12447 2001 DRUG METABOLISM AND DISPOSITION 29(6):798-805 Hashizume T; Mise M; Matsumoto S; Terauchi Y; Fujii T; Imaoka S; Funae Y; Kamataki T; Miyazaki H A novel cytochrome P450 enzyme responsible for the metabolism of ebastine in monkey small intestine	1	1
4324	12	11173 1998 DRUG METABOLISM AND DISPOSITION 26(6):566-571 Hashizume T; Mise M; Terauchi Y; O L; Fujii T; Miyazaki H; Inaba T N-dealkylation and hydroxylation of ebastine by human liver cytochrome P450	17	3
4325	3	5697 1986 JOURNAL OF NUTRITION 116(4):682-688 HASHMI RS; SIDDIQUI AM; KACHOLE MS; PAWAR SS ALTERATIONS IN HEPATIC-MICROSOMAL MIXED-FUNCTION OXIDASE SYSTEM DURING DIFFERENT LEVELS OF FOOD RESTRICTION IN ADULT MALE AND FEMALE RATS	21	4
4326	19	9305 1994 MOLECULAR PHARMACOLOGY 46(2):338-345 HASLER JA; HARLOW GR; SZKLARZ GD; JOHN GH; KEDZIE KM; BURNETT VL; HE YA; KAMINSKY LS; HALPERT JR SITE-DIRECTED MUTAGENESIS OF PUTATIVE SUBSTRATE RECOGNITION SITES IN CYTOCHROME-P450-2B11 - IMPORTANCE OF AMINO-ACID RESIDUE-114, RESIDUE-290, AND RESIDUE-363 FOR SUBSTRATE- SPECIFICITY	46	23
4327	10	3786 1979 BIOCHEMICAL PHARMACOLOGY 28(21):3199-3203 HASSALL KA; ADDALA SA USE OF A DIMETHYLATED OXIRANE TO CHARACTERIZE MICROSOMAL MONO- OXYGENASES IN RAT-LIVER	9	3
4328	1	5900 1987 GENERAL PHARMACOLOGY 18(5):547-550 HASSAN MQ; MOHAMMADPOUR H; HERMANSKY SJ; MURRAY WJ; STOHS SJ COMPARATIVE EFFECTS OF BHA AND ASCORBIC-ACID ON THE TOXICITY OF 2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN (TCDD) IN RATS	8	0
4329	3	6547 1989 DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY 8(1):29-37 HASSETT C; LUCHTEL DL; OMIECINSKI CJ HEPATIC EXPRESSION OF RAT P450 MESSENGER-RNA ASSESSED BY INSITU HYBRIDIZATION TO OLIGOMER PROBES	20	9
4330	4	5782 1987 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 149(2):326-333 HASSETT C; OMIECINSKI CJ USE OF A CONSERVED CONSENSUS OLIGOMER IN THE IDENTIFICATION OF CYTOCHROME-P-450 MESSENGER-RNAS	5	2
4331	14	7255 1990 NUCLEIC ACIDS RESEARCH 18(6):1429-1434 HASSETT C; OMIECINSKI CJ SEQUENCE AND GENE-EXPRESSION OF RABBIT CYTOCHROME P450 IIC16 - COMPARISON TO HIGHLY RELATED FAMILY MEMBERS	18	12
4332	6	577 1967 ANNALES MEDICINAE EXPERIMENTALIS ET BIOLOGIAE FENNIAE 45(1):46-& HASSINEN I HYDROGEN TRANSFER INTO MITOCHONDRIA IN METABOLISM OF ETHANOL .2. EFFECT OF DISULFIRAM ON HYDROGEN AND ENERGY TRANSFER	11	1
4333	3	628 1967 BIOCHEMICAL PHARMACOLOGY 16(11):2155-& HASSINEN I; HALLMAN M COMPARISON OF EFFECTS OF DISULFIRAM AND DIMERCAPTOPROPANOL ARSENITE ON MITOCHONDRIAL STRUCTURE AND FUNCTION	8	0
4334	10	2005 1972 SCIENCE 176(4042):1435-& HASSINEN IE; YLIKAHRI RH MIXED FUNCTION OXIDASE AND ETHANOL METABOLISM IN PERFUSED RAT- LIVER	13	4
4335	4	2061 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 155(2):258-269 HASSON EP; WEST CA MICROSOMAL ATP-ACTIVATED PYRIDINE-NUCLEOTIDE TRANSHYDROGENASE	11	3
4336	7	3187 1976 PLANT PHYSIOLOGY 58(4):473-478 HASSON EP; WEST CA PROPERTIES OF SYSTEM FOR MIXED-FUNCTION OXIDATION OF KAURENE AND KAURENE DERIVATIVES IN MICROSOMES OF IMMATURE SEED OF MARAH-MACROCARPUS - COFACTOR REQUIREMENTS	32	3
4337	18	3188 1976 PLANT PHYSIOLOGY 58(4):479-484 HASSON EP; WEST CA PROPERTIES OF SYSTEM FOR MIXED-FUNCTION OXIDATION OF KAURENE AND KAURENE DERIVATIVES IN MICROSOMES OF IMMATURE SEED OF MARAH-MACROCARPUS - ELECTRON-TRANSFER COMPONENTS	30	9
4338	1	10296 1996 JOURNAL OF MOLECULAR EVOLUTION 42(6):631-640 Hastings KEM Strong evolutionary conservation of broadly expressed protein isoforms in the troponin I gene family and other vertebrate gene families	24	0
4339	12	7771 1991 PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS 42(3):171-175 HASUNUMA K; TERANO T; TAMURA Y; YOSHIDA S FORMATION OF EPOXYEICOSATRIENOIC ACIDS FROM ARACHIDONIC-ACID BY CULTURED RAT AORTIC SMOOTH-MUSCLE CELL MICROSOMES	11	3
4340	3	12563 2001 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 123(26):6410-6416 Hata M; Hirano Y; Hoshino T; Tsuda M Monooxygenation mechanism by cytochrome P-450	9	1
4341	10	12403 2001 CARCINOGENESIS 22(12):2033-2038 Hatanaka N; Yamazaki H; Kizu R; Hayakawa K; Aoki Y; Iwanari M; Nakajima M; Yokoi T Induction of cytochrome P4501B1 in lung, liver and kidney of rats exposed to diesel exhaust	4	1
4342	10	12592 2001 MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS 497(1-2):223-233 Hatanaka N; Yamazaki H; Oda Y; Guengerich FP; Nakajima M; Yokoi T Metabolic activation of carcinogenic 1-nitropyrene by human cytochrome P4501B1 in Salmonella typhimurium strain expressing an O-acetyltransferase in SOS/umu assay	2	1
4343	6	6609 1989 HISTOCHEMISTRY 91(2):89-97 HATANO O; SAGARA Y; OMURA T; TAKAKUSU A IMMUNOCYTOCHEMICAL LOCALIZATION OF ADRENODOXIN IN BOVINE ADRENAL-CORTEX BY PROTEIN-A-GOLD TECHNIQUE	8	2
4344	2	7549 1991 ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 17(1):4-19 HATCH FT; KNIZE MG; FELTON JS QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS OF HETEROCYCLIC AMINE MUTAGENS FORMED DURING THE COOKING OF FOOD	34	0
4345	8	402 1965 CLINICAL CHEMISTRY 11(2SP2):198-& HATEFI Y RECENT ADVANCES IN ELECTRON TRANSFER AND OXIDATIVE PHOSPHORYLATION	1	0
4346	3	126 1961 BIOCHIMICA ET BIOPHYSICA ACTA 52(1):106-& HATEFI Y; HAAVIK AG; JURTSHUK P STUDIES ON ELECTRON TRANSPORT SYSTEM .30. DPNH-CYTOCHROME C REDUCTASE 1	139	21
4347	4	127 1961 BIOCHIMICA ET BIOPHYSICA ACTA 52(1):119-& HATEFI Y; HAAVIK AG; JURTSHUK P STUDIES ON ELECTRON TRANSPORT SYSTEM .31. DPNH-CYTOCHROME C REDUCTASE 2	34	11
4348	7	1112 1969 JOURNAL OF BIOLOGICAL CHEMISTRY 244(9):2350-& HATEFI Y; STEMPEL KE ISOLATION AND ENZYMATIC PROPERTIES OF MITOCHONDRIAL REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE DEHYDROGENASE	135	13
4349	4	1113 1969 JOURNAL OF BIOLOGICAL CHEMISTRY 244(9):2358-& HATEFI Y; STEMPEL KE; HANSTEIN WG INHIBITORS AND ACTIVATORS OF MITOCHONDRIAL REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE DEHYDROGENASE	39	5
4350	16	5195 1984 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 21(3):265-277 HATTORI MA; AQUILANO DR; DUFAU ML AN EARLY STEROIDOGENIC DEFECT IN HORMONE-INDUCED LEYDIG-CELL DESENSITIZATION	13	1
4351	4	9677 1995 FOOD SCIENCE AND TECHNOLOGY-LEBENSMITTEL-WISSENSCHAFT & TECHNOLOGIE 28(1):135-138 HATTORI T; OHISHI H; YOKOTA T; OHOAMI H; WATANABE K ANTIOXIDATIVE EFFECT OF CRUDE ANTIOXIDANT PREPARATION FROM SOYBEAN FERMENTED BY BACILLUS-NATTO	1	0
4352	14	11917 2000 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 379(1):127-136 Haudenschild C; Schalk M; Karp F; Croteau R Functional expression of regiospecific cytochrome P450 limonene hydroxylases from mint (Mentha spp.) in Escherichia coli and Saccharomyces cerevisiae	14	3
4353	2	1026 1969 BIOCHIMICA ET BIOPHYSICA ACTA 172(2):198-& HAUGAARD N; LEE NH; KOSTRZEW.R; HORN RS; HAUGAARD ES ROLE OF SULFHYDRYL GROUPS IN OXIDATIVE PHOSPHORYLATION AND ION TRANSPORT BY RAT LIVER MITOCHONDRIA	101	9
4354	18	3139 1976 JOURNAL OF BIOLOGICAL CHEMISTRY 251(24):7929-7939 HAUGEN DA; COON MJ PROPERTIES OF ELECTROPHORETICALLY HOMOGENEOUS PHENOBARBITAL- INDUCIBLE AND BETA-NAPHTHOFLAVONE-INDUCIBLE FORMS OF LIVER MICROSOMAL CYTOCHROME-P-450	623	218
4355	6	4973 1983 MUTATION RESEARCH 116(3-4):257-269 HAUGEN DA; PEAK MJ MIXTURES OF POLYCYCLIC AROMATIC-COMPOUNDS INHIBIT MUTAGENESIS IN THE SALMONELLA MICROSOME ASSAY BY INHIBITION OF METABOLIC- ACTIVATION	57	0
4356	13	2848 1975 JOURNAL OF BIOLOGICAL CHEMISTRY 250(9):3567-3570 HAUGEN DA; VANDERHOEVEN TA; COON MJ PURIFIED LIVER MICROSOMAL CYTOCHROME-P-450 - SEPARATION AND CHARACTERIZATION OF MULTIPLE FORMS	473	170
4357	10	5433 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260(28):5059-5067 HAURAND M; ULLRICH V ISOLATION AND CHARACTERIZATION OF THROMBOXANE SYNTHASE FROM HUMAN-PLATELETS AS A CYTOCHROME-P-450 ENZYME	155	0
4358	7	2832 1975 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 6(7):455-458 HAUSER CA; BAILEY E EFFECT OF DIET AND THYROXINE ADMINISTRATION ON MALIC ENZYME ACTIVITY IN VARIOUS TISSUES OF LABORATORY RAT	2	0
4359	2	4119 1980 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 12(5-6):981-984 HAUST HL; HEAGY FC ABNORMAL PERCHLORATE-INDUCED RADIO-IODIDE LOSS FROM THE THYROID-GLAND IN PORPHYRINOPATHIES	2	0
4360	12	6008 1988 AMBIO 17(6):376-380 HAUX C; FORLIN L BIOCHEMICAL METHODS FOR DETECTING EFFECTS OF CONTAMINANTS ON FISH	59	11
4361	6	10778 1997 JOURNAL OF LIPID RESEARCH 38(6):1189-1203 Hawke RL; Chapman JM; Winegar DA; Salisbury JA; Welch RM; Brown A; Franzmann KW; Sigel C Potent hypocholesterolemic activity of novel ureido phenoxyisobutyrates correlates with their intrinsic fibrate potency and not with their ACAT inhibitory activity	6	0
4362	7	5470 1985 MOLECULAR PHARMACOLOGY 28(3):283-289 HAWKE RL; WELCH RM MAJOR DIFFERENCES IN THE SPECIFICITY AND REGULATION OF MOUSE RENAL CYTOCHROME P-450-DEPENDENT MONOOXYGENASES - A COMPARISON OF XENOBIOTIC AND ENDOGENOUS SUBSTRATES	6	2
4363	17	12850 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(31):27725-27732 Hawkes DB; Adams GW; Burlingame AL; de Montellano PRO; De Voss JJ Cytochrome P450(cin) (CYP176A), isolation, expression, and characterization	2	0
4364	1	6021 1988 ANALYTICAL BIOCHEMISTRY 173(2):456-462 HAWKINS DJ; KUHN H; PETTY EH; BRASH AR RESOLUTION OF ENANTIOMERS OF HYDROXYEICOSATETRAENOATE DERIVATIVES BY CHIRAL PHASE HIGH-PRESSURE LIQUID-CHROMATOGRAPHY	30	6
4365	22	5884 1987 DRUG METABOLISM REVIEWS 18(4):441-515 HAWKINS JM; JONES WE; BONNER FW; GIBSON GG THE EFFECT OF PEROXISOME PROLIFERATORS ON MICROSOMAL, PEROXISOMAL, AND MITOCHONDRIAL ENZYME-ACTIVITIES IN THE LIVER AND KIDNEY	216	39
4366	19	1993 1972 PHARMACOLOGICAL REVIEWS 24(1):67-& HAWKINS RD; KALANT H METABOLISM OF ETHANOL AND ITS METABOLIC EFFECTS	284	8
4367	10	12797 2002 ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 21(9):1845-1853 Hawkins SA; Billiard SM; Tabash SP; Brown RS; Hodson PV Altering cytochrome p4501a activity affects polycyclic aromatic hydrocarbon metabolism and toxicity in rainbow trout (Oncorhynchus mykiss)	0	0
4368	7	1512 1971 BIOCHEMICAL PHARMACOLOGY 20(9):2221-& HAWKINS SF; HANKINSO.JB; MERRITT JH; MEDINA MA EFFECT OF REDUCED BAROMETRIC PRESSURE ON DRUG ACTION AND METABOLISM IN MICE	8	2
4369	20	956 1969 ANNUAL REVIEW OF BIOCHEMISTRY 38():21-& HAYAISHI O ENZYMIC HYDROXYLATION	128	26
4370	3	3134 1976 JOURNAL OF BIOLOGICAL CHEMISTRY 251(18):5759-5769 HAYASHI E; HASEGAWA R; TOMITA T ACCUMULATION OF NEUTRAL LIPIDS IN SACCHAROMYCES-CARLSBERGENSIS BY MYOINOSITOL DEFICIENCY AND ITS MECHANISM - RECIPROCAL REGULATION OF YEAST ACETYL-COA CARBOXYLASE BY FRUCTOSE BISPHOSPHATE AND CITRATE	29	0
4371	16	11921 2000 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 381(1):164-170 Hayashi K; Sakaki T; Kominami S; Inouye K; Yabusaki Y Coexpression of genetically engineered fused enzyme between yeast NADPH-P450 reductase and human cytochrome P450 3A4 and human cytochrome b(5) in yeast	9	4
4372	15	5367 1985 DIGESTIVE DISEASES AND SCIENCES 30(4):334-339 HAYASHI N; KAMADA T; SATO N; KASAHARA A; PETERSON JA INHIBITION OF CYTOCHROME-P-450-DEPENDENT MIXED-FUNCTION OXIDATION BY ETHANOL	6	0
4373	10	13109 2003 PROTEIN EXPRESSION AND PURIFICATION 29(1):1-7 Hayashi S; Omata Y; Sakamoto H; Hara T; Noguchi M Purification and characterization of a soluble form of rat liver NADPH-cytochrome P-450 reductase highly expressed in Escherichia coli	0	0
4374	9	7611 1991 JOURNAL OF BIOCHEMISTRY 110(3):407-411 HAYASHI S; WATANABE J; NAKACHI K; KAWAJIRI K GENETIC-LINKAGE OF LUNG CANCER-ASSOCIATED MSPI POLYMORPHISMS WITH AMINO-ACID REPLACEMENT IN THE HEME BINDING REGION OF THE HUMAN CYTOCHROME-P450IA1 GENE	285	38
4375	1	2181 1973 CYTOBIOLOGIE 7(3):289-296 HAYASHID.Y GIGANTIC MITOCHONDRIA OF SPINAL GANGLION-CELLS IN RAT	5	0
4376	17	9592 1995 CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY 30(6):445-600 Hayes JD; Pulford DJ The glutathione S-Transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance	983	26
4377	27	2435 1974 BIOCHEMICAL PHARMACOLOGY 23(12):1721-1731 HAYES JR; CAMPBELL TC EFFECT OF PROTEIN-DEFICIENCY ON INDUCIBILITY OF HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM .3. EFFECT OF 3- METHYLCHOLANTHRENE INDUCTION ON ACTIVITY AND BINDING KINETICS	38	6
4378	17	2909 1975 TOXICOLOGY AND APPLIED PHARMACOLOGY 32(3):559-565 HAYES JR; HARTGROVE RW; HUNDLEY SG; CAMPBELL TC; WEBB RE INTERACTION OF ENDRIN AND DIELDRIN WITH HEPATIC MICROSOMAL CYTOCHROME-P-450 FROM RAT, MOUSE, AND ENDRIN-SUSCEPTIBLE AND RESISTANT PINE VOLES	2	1
4379	11	2100 1973 BIOCHEMICAL PHARMACOLOGY 22(9):1005-1014 HAYES JR; MGBODILE MU; CAMPBELL TC EFFECT OF PROTEIN-DEFICIENCY ON INDUCIBILITY OF HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM .1. EFFECT ON SUBSTRATE INTERACTION WITH CYTOCHROME-P-450	57	9
4380	11	2105 1973 BIOCHEMICAL PHARMACOLOGY 22(12):1517-1520 HAYES JR; MGBODILE MU; CAMPBELL TC DEPENDENCE OF KM AN VMAX ON SUBSTRATE CONCENTRATION FOR RAT HEPATIC MICROSOMAL ETHYLMORPHINE N-DEMETHYLASE	24	7
4381	5	3000 1976 BIOCHEMICAL PHARMACOLOGY 25(13):1495-1500 HAYES JS; BRENDEL K N-DEMETHYLATION AS AN EXAMPLE OF DRUG-METABOLISM IN ISOLATED RAT HEPATOCYTES	39	2
4382	7	6619 1989 JOURNAL OF APPLIED PHYSIOLOGY 67(6):2586-2592 HAZINSKI TA; FRANCE M; KENNEDY KA; HANSEN TN CIMETIDINE REDUCES HYPEROXIC LUNG INJURY IN LAMBS	13	3
4383	7	9740 1995 JOURNAL OF CLINICAL INVESTIGATION 96(4):2083-2089 HAZINSKI TA; NOISIN E; HAMON I; DEMATTEO A SHEEP LUNG CYTOCHROME P4501A1 (CYP1A1) - CDNA CLONING AND TRANSCRIPTIONAL REGULATION BY OXYGEN-TENSION	17	4
4384	2	7436 1991 BIOCHEMISTRY 30(18):4559-4564 HAZZARD JT; MCINTIRE WS; TOLLIN G LASER FLASH-PHOTOLYSIS STUDY OF INTERMOLECULAR AND INTRAMOLECULAR ELECTRON-TRANSFER IN TRIMETHYLAMINE DEHYDROGENASE	2	0
4385	12	12832 2002 INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 32(3):303-309 He H; Chen AC; Davey RB; Ivie GW Molecular cloning and nucleotide sequence of a new P450 gene, CYP319A1, from the cattle tick, Boophilus microplus	0	0
4386	12	7942 1992 BIOCHEMISTRY 31(38):9220-9226 HE YA; BALFOUR CA; KEDZIE KM; HALPERT JR ROLE OF RESIDUE-478 AS A DETERMINANT OF THE SUBSTRATE- SPECIFICITY OF CYTOCHROME-P450-2B1	55	29
4387	19	8988 1994 BIOCHEMISTRY 33(14):4419-4424 HE YA; LUO ZS; KLEKOTKA PA; BURNETT VL; HALPERT JR STRUCTURAL DETERMINANTS OF CYTOCHROME-P450-2B1 SPECIFICITY - EVIDENCE FOR 5 SUBSTRATE RECOGNITION SITES	58	34
4388	22	10971 1998 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 350(2):333-339 He YQ; Harlow GR; Szklarz GD; Halpert JR Structural determinants of progesterone hydroxylation by cytochrome P450 2B5: The role of nonsubstrate recognition site residues	14	8
4389	18	9572 1995 CHEMICAL RESEARCH IN TOXICOLOGY 8(4):574-579 HE YQ; HE YA; HALPERT JR ESCHERICHIA-COLI EXPRESSION OF SITE-DIRECTED MUTANTS OF CYTOCHROME-P450 2B1 FROM 6 SUBSTRATE RECOGNITION SITES - SUBSTRATE-SPECIFICITY AND INHIBITOR SELECTIVITY STUDIES	47	21
4390	19	12323 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 389(2):264-270 He YQ; Roussel F; Halpert JR Importance of amino acid residue 474 for substrate specificity of canine and human cytochrome p450 3A enzymes	1	0
4391	20	9984 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 335(1):152-160 He YQ; Szklarz GD; Halpert JR Interconversion of the androstenedione hydroxylase specificities of cytochromes p450 2B4 and 2B5 upon simultaneous site-directed mutagenesis of four key substrate recognition residues	18	9
4392	16	12695 2002 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 407(1):95-102 Headlam MJ; Tuckey RC The effect of glycerol on cytochrome P450scc (CYP11A1) spin state, activity, and hydration	0	0
4393	1	3946 1979 PLANT PHYSIOLOGY 64(2):224-227 HEATH RL CONSTITUTIVE ENZYME-SYSTEM FOR GLUCOSE-TRANSPORT BY CHLORELLA- SOROKINIANA	3	0
4394	7	10411 1996 TETRAHEDRON LETTERS 37(9):1425-1428 Heckmann B; Mioskowski C; Lumin S; Falck JR; Wei SZ; Capdevila JH Chiral acetals: Stereocontrolled syntheses of 16-, 17-, and 18- hydroxyeicosatetraenoic acids, cytochrome P-450 arachidonate metabolites	9	1
4395	56	12432 2001 CURRENT DRUG METABOLISM 2(3):245-263 Hedlund E; Gustafsson JA; Warner M Cytochrome P450 in the brain; A review	5	0
4396	9	10354 1996 MOLECULAR PHARMACOLOGY 50(2):342-350 Hedlund E; Wyss A; Kainu T; Backlund M; Kohler C; PeltoHuikko M; Gustafsson JA; Warner M Cytochrome P4502D4 in the brain: Specific neuronal regulation by clozapine and toluene	16	9
4397	5	157 1962 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 8(4):314-& HEDMAN R; SURANYI EM; LUFT R; ERNSTER L OXIDATION OF EXTERNAL DPNH BY MITOCHONDRIA FROM HUMAN AND RAT SKELETAL MUSCLE	22	7
4398	1	1262 1970 BIOCHIMICA ET BIOPHYSICA ACTA 212(1):8-& HEICK HMC; BARRETTE M ALCOHOL DEHYDROGENASE ACTIVITY IN YEAST LIPOMYCES-STARKEYI	13	1
4399	1	1046 1969 BIOCHIMICA ET BIOPHYSICA ACTA 191(3):493-& HEICK HMC; WILLEMOT J; BEGINHEI.N SUBCELLULAR LOCALIZATION OF ALCOHOL DEHYDROGENASE ACTIVITY IN BAKERS YEAST	36	3
4400	4	6177 1988 DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY 7(6):379-387 HEILMANN LJ; SHEEN YY; BIGELOW SW; NEBERT DW TROUT-P450IA1 - CDNA AND DEDUCED PROTEIN-SEQUENCE, EXPRESSION IN LIVER, AND EVOLUTIONARY SIGNIFICANCE	191	88

#	Cited nodes	Nodes / Authors	GCS	LCS
4401	4	7206 1990 LANCET 336(8714):529-532 HEIM M; MEYER UA GENOTYPING OF POOR METABOLIZERS OF DEBRISOQUINE BY ALLELE- SPECIFIC PCR AMPLIFICATION	384	46
4402	10	8127 1992 GENOMICS 14(1):49-58 HEIM MH; MEYER UA EVOLUTION OF A HIGHLY POLYMORPHIC HUMAN CYTOCHROME P450 GENE- CLUSTER - CYP2D6	76	19
4403	2	10838 1997 MUSCLE & NERVE 20(10):1219-1224 HeimanPatterson TD; Argov Z; Chavin JM; Kalman B; Alder H; DiMauro S; Bank W; Tahmoush AJ Biochemical and genetic studies in a family with mitochondrial myopathy	2	0
4404	7	5619 1986 CHEMICO-BIOLOGICAL INTERACTIONS 59(2):219-230 HEINE HS; STOSKOPF MK; THOMPSON DC; CHA YN ENHANCEMENT OF EPOXIDE HYDROLASE ACTIVITY IN HEPATIC MICROSOMES OF MICE GIVEN HETEROCYCLIC-COMPOUNDS	3	1
4405	8	4188 1980 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 314(2):201-210 HEINEMEYER G; NIGAM S; HILDEBRANDT AG HEXOBARBITAL-BINDING, HYDROXYLATION AND HEXOBARBITAL-DEPENDENT HYDROGEN-PEROXIDE PRODUCTION IN HEPATIC MICROSOMES OF GUINEA- PIG, RAT AND RABBIT	22	8
4406	10	10173 1996 ENVIRONMENTAL HEALTH PERSPECTIVES 104(5):536-543 Heinonen JT; Sidhu JS; Reilly MT; Farin FM; Omiecinski CJ; Eaton DL; Kavanagh TJ Assessment of regional cytochrome P450 activities in rat liver slices using resorufin substrates and fluorescence confocal laser cytometry	13	2
4407	3	4036 1980 BIOCHEMICAL PHARMACOLOGY 29(19):2675-2679 HEINONEN T; VAINIO H VINYLTOLUENE INDUCED CHANGES IN XENOBIOTIC-METABOLIZING ENZYME- ACTIVITIES AND TISSUE GLUTATHIONE CONTENT IN VARIOUS RODENT SPECIES	7	0
4408	8	797 1968 BIOCHEMISTRY 7(6):2273-& HEINRICH.WL; COLAS A SELECTIVE STIMULATION INHIBITION AND PHYSICOCHEMICAL ALTERATION OF 7-AND 16ALPHA-HYDROXYLASES OF 3BETA-HYDROXYANDROST-5-EN-17- ONE AND DRUG-METABOLIZING ENZYMES IN HEPATIC MICROSOMAL FRACTIONS	29	0
4409	9	6062 1988 BIOCHEMICAL JOURNAL 254(1):101-108 HEIRWEGH KPM; MEUWISSEN JATP; VERMEIR M; DESMEDT H LIPOSOMES AS CARRIERS OF POORLY WATER-SOLUBLE SUBSTRATES - LINEAR MODELING OF MEMBRANE SYSTEMS WITH CATALYTIC OR BINDING- SITES OF DIFFERENT FACEDNESS - SIGNIFICANCE OF EXPERIMENTAL MEMBRANE PARTITION-COEFFICIENTS AND OF KINETIC AND EQUILIBRIUM PARAMETERS	18	3
4410	9	7782 1991 STROKE 22(11):1389-1393 HEIZER ML; MCKINNEY JS; ELLIS EF 14,15-EPOXYEICOSATRIENOIC ACID INHIBITS PLATELET-AGGREGATION IN MOUSE CEREBRAL ARTERIOLES	7	4
4411	1	171 1962 BIOCHIMICA ET BIOPHYSICA ACTA 65(3):461-& HELLE KB; KLUNGSOYR L MANNITOL 1-PHOSPHATE FORMATION IN ESCHERICHIA COLI DURING GLUCOSE UTILIZATION	19	0
4412	4	12633 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(4):2065-2070 Helliwell CA; Chandler PM; Poole A; Dennis ES; Peacock WJ The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway	27	1
4413	18	9820 1995 MOLECULAR PHARMACOLOGY 48(4):630-638 HELLMOLD H; LAMB JG; WYSS A; GUSTAFSSON JA; WARNER M DEVELOPMENTAL AND ENDOCRINE REGULATION OF P450 ISOFORMS IN RAT BREAST	22	6
4414	9	11333 1998 MOLECULAR PHARMACOLOGY 53(3):475-482 Hellmold H; Magnusson M; Pelto-Huikko M; Rylander T; Gustafsson JA; Warner M Identification of CYP2A3 as a major cytochrome P450 enzyme in the female peripubertal rat breast	4	1
4415	22	11280 1998 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 83(3):886-895 Hellmold H; Rylander T; Magnusson M; Reihner E; Warner M; Gustafsson JA Characterization of cytochrome P450 enzymes in human breast tissue from reduction mammaplasties	22	7
4416	19	8357 1993 ACTA ENDOCRINOLOGICA 129(2):97-108 HELMBERG A TWIN GENES AND ENDOCRINE DISEASE - CYP21 AND CYP11B GENES	12	0
4417	9	8041 1992 DNA AND CELL BIOLOGY 11(5):359-368 HELMBERG A; TABARELLI M; FUCHS MA; KELLER E; DOBLER G; SCHNEGG I; KNORR D; ALBERT E; KOFLER R IDENTIFICATION OF MOLECULAR DEFECTS CAUSING CONGENITAL ADRENAL- HYPERPLASIA BY CLONING AND DIFFERENTIAL HYBRIDIZATION OF POLYMERASE CHAIN REACTION-AMPLIFIED 21-HYDROXYLASE (CYP21) GENES	11	1
4418	31	11955 2000 BIOCHEMISTRY 39(17):5196-5205 Helvig C; Capdevila JH Biochemical characterization of rat P4502C11 fused to rat or bacterial NADPH-P450 reductase domains	3	3
4419	24	11047 1998 BIOCHEMISTRY 37(36):12546-12558 Helvig C; Dishman E; Capdevila JH Molecular, enzymatic, and regulatory characterization of rat kidney cytochromes P450 4A2 and 4A3	28	10
4420	1	214 1963 BIOCHIMICA ET BIOPHYSICA ACTA 73(2):311-& HEMKER HC CONTRIBUTION OF VARIOUS PHOSPHORYLATING STEPS IN RESPIRATORY CHAIN TO DINITROPHENOL-INDUCED ATPASE OF RAT-LIVER MITOCHONDRIA	38	5
4421	2	12740 2002 CELL BIOCHEMISTRY AND FUNCTION 20(1):47-59 Hemmings SJ; Pulga VB; Tran ST; Uwiera RRE Differential inhibitory effects of carbon tetrachloride on the hepatic plasma membrane, mitochondrial and endoplasmic reticular calcium transport systems: implications to hepatotoxicity	1	0
4422	3	3071 1976 DRUGS 12(6):442-448 HEMPEL E; KLINGER W DRUG STIMULATED BIOTRANSFORMATION OF HORMONAL STEROID CONTRACEPTIVES - CLINICAL IMPLICATIONS	34	0
4423	5	2646 1975 ANAESTHESIST 24(9):400-403 HEMPEL V; KUGELGEN CV; REMMER H INFLUENCE OF VOLATILE ANESTHETICS ON DRUG-METABOLISM IN LIVER	20	2
4424	3	645 1967 BIOCHIMICA ET BIOPHYSICA ACTA 141(2):391-& HEMPFLIN.WP; HOFER M; HARRIS EJ; PRESSMAN BC CORRELATION BETWEEN CHANGES IN METABOLITE CONCENTRATIONS AND RATE OF ION TRANSPORT FOLLOWING GLUCOSE ADDITION TO ESCHERICHIA COLI B	26	0
4425	2	1009 1969 BIOCHEMICAL PHARMACOLOGY 18(9):2087-& HENDERSO.PT; DEWAIDE JH METABOLISM OF DRUGS IN ISOLATED RAT HEPATOCYTES	48	0
4426	17	9008 1994 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1200(2):182-190 HENDERSON CJ; BAMMLER T; WOLF CR DEDUCED AMINO-ACID-SEQUENCE OF A MURINE CYTOCHROME-P-450 CYP4A PROTEIN - DEVELOPMENTAL AND HORMONAL-REGULATION IN LIVER AND KIDNEY	22	11
4427	17	13070 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(15):13480-13486 Henderson CJ; Otto DME; Carrie D; Magnuson MA; McLaren AW; Rosewell I; Wolf CR Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase	1	1
4428	10	7956 1992 BIOCHIMICA ET BIOPHYSICA ACTA 1118(2):99-106 HENDERSON CJ; RUSSELL AL; ALLAN JA; WOLF CR SEXUAL-DIFFERENTIATION AND REGULATION OF CYTOCHROME-P-450 CYP2C7	8	1
4429	9	6864 1990 BIOCHEMICAL JOURNAL 266(3):675-681 HENDERSON CJ; SCOTT AR; YANG CS; WOLF CR TESTOSTERONE-MEDIATED REGULATION OF MOUSE RENAL CYTOCHROME-P- 450 ISOENZYMES	44	21
4430	7	7397 1991 BIOCHEMICAL JOURNAL 278():499-503 HENDERSON CJ; WOLF CR EVIDENCE THAT THE ANDROGEN RECEPTOR MEDIATES SEXUAL- DIFFERENTIATION OF MOUSE RENAL CYTOCHROME-P450 EXPRESSION	27	11
4431	7	5703 1986 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 25(5B):867-876 HENDERSON D; HABENICHT UF; NISHINO Y; KERB U; ELETREBY MF AROMATASE INHIBITORS AND BENIGN PROSTATIC HYPERPLASIA	41	1
4432	6	5627 1986 DEVELOPMENTAL PHARMACOLOGY AND THERAPEUTICS 9(3):201-216 HENDERSON G; SECOR J; HEITMAN D; SCHENKER S EFFECTS OF AGE AND SEX ON THE HEPATIC MONO-OXYGENASE SYSTEM - A CORRELATIVE APPROACH	11	1
4433	9	5523 1986 ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 10(3):259-265 HENDERSON GI; SCHENKER S EFFECTS OF AGE, SEX, AND CIMETIDINE ON ACUTE ETHANOL-INDUCED INHIBITION OF THE HEPATIC MONOOXYGENASE SYSTEMS	2	0
4434	5	6083 1988 BIOCHEMICAL PHARMACOLOGY 37(13):2667-2673 HENDERSON GI; SPEEG KV; ROBERTS RK; PEREZ A; SCHENKER S EFFECT OF AGING ON HEPATIC ELIMINATION OF CIMETIDINE AND SUBSEQUENT INTERACTION OF AGING AND CIMETIDINE ON AMINOPYRINE METABOLISM	2	0
4435	8	3609 1978 GENERAL PHARMACOLOGY 9(1):59-63 HENDERSON PT DIFFERENT DEVELOPMENTAL PROFILES FOR HEPATIC N-DEMETHYLATION OF N-METHYLAMPHETAMINE AND N,N-DIMETHYLAMPHETAMINE IN RAT	4	0
4436	20	10545 1997 BIOCHEMICAL JOURNAL 325():741-749 Heng YM; Kuo CWS; Jones PS; Savory R; Schulz RM; Tomlinson SR; Gray TJB; Bell DR A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b but not of CYP4F, genes in mouse and humans	26	10
4437	4	1583 1971 EXPERIENTIA 27(3):293-& HENI N MODULATION OF MICROSOMAL ENZYMES BY CARBON TETRACHLORIDE WITH AND WITHOUT PHENOBARBITAL TREATMENT	7	3
4438	8	1584 1971 EXPERIENTIA 27(7):777-& HENI N DECREASE IN CYTOCHROME-P450 FOLLOWING INCUBATION WITH CCL4 IN AN NADPH REGENERATING SYSTEMS AND PARTIAL CONVERSION INTO CYTOCHROME-P420	2	1
4439	9	1436 1971 ARCHIV FUR TOXIKOLOGIE 28(1):1-& HENI N; REMMER H EFFECT OF CARBON TETRACHLORIDE ON ENDOPLASMIC ENZYMES OF RAT LIVER	16	3
4440	1	403 1965 CLINICAL CHEMISTRY 11(2SP2):247-& HENLEY KS DISCUSSION OF SYMPOSIUM ON ENZYMES IN CLINICALCHEMISTRY	0	0
4441	2	330 1964 JOURNAL OF LABORATORY AND CLINICAL MEDICINE 64(2):306-& HENLEY KS; KREYDEN RW; NAPIER EA; CORSSEN GC; BERENDSO.S MITOCHONDRIAL OXIDASE ACTIVITIES + PYRIDINE NUCLEOTIDE CONCENTRATIONS OF NORMAL HUMAN LIVER	10	2
4442	2	363 1965 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 111(3):692-& HENLEY KS; LAUGHREY EG SUCCINATE OXIDATION BY HUMAN LIVER MITOCHONDRIA	2	0
4443	2	434 1965 NATURE 205(4972):707-& HENLEY KS; LAUGHREY EG MITOCHONDRIAL PYRIDINE NUCLEOTIDES IN OXIDATION OF ISOCITRATE AND MALATE	1	0
4444	5	2564 1974 JOURNAL OF BIOLOGICAL CHEMISTRY 249(23):7529-7535 HENRY HL; NORMAN AW STUDIES ON CALCIFEROL METABOLISM .9. RENAL "25-HYDROXY-VITAMIN- D3-1-HYDROXYLASE - INVOLVEMENT OF CYTOCHROME-P-450 AND OTHER PROPERTIES	138	14
4445	15	11288 1998 JOURNAL OF EXPERIMENTAL ZOOLOGY 280(1):1-7 Herman CA; Oliw EH Liver microsomes from the yellow aat snake (Elaphe obsoleta) and American bullfrog (Rana catesbeiana) oxidize polyunsaturated fatty acids by NADPH-dependent hydroxylation and epoxidation	0	0
4446	7	11558 1999 CANADIAN MEDICAL ASSOCIATION JOURNAL 161(10):1281-1286 Herman RJ Drug interactions and the statins	25	2
4447	8	8534 1993 BRITISH JOURNAL OF PHARMACOLOGY 110(1):482-490 HERMANS JJR; THIJSSEN HHW HUMAN LIVER MICROSOMAL METABOLISM OF THE ENANTIOMERS OF WARFARIN AND ACENOCOUMAROL - P450 ISOZYME DIVERSITY DETERMINES THE DIFFERENCES IN THEIR PHARMACOKINETICS	38	8
4448	5	625 1967 BIOCHEMICAL PHARMACOLOGY 16(10):1877-& HERNANDE.PH; MAZEL P; GILLETTE JR STUDIES ON MECHANISM OF ACTION OF MAMMALIAN HEPATIC AZOREDUCTASE .2. EFFECTS OF PHENOBARBITAL AND 3- METHYLCHOLANTHRENE ON CARBON MONOXIDE SENSITIVE AND INSENSITIVE AZOREDUCTASE ACTIVITIES	89	0
4449	4	228 1963 DEVELOPMENTAL BIOLOGY 8(1):67-& HEROLD RC; BOREI H CYTOCHROME CHANGES DURING HONEY BEE FLIGHT MUSCLE DEVELOPMENT	31	0
4450	2	700 1967 JOURNAL OF LIPID RESEARCH 8(5):515-& HERRERA E; FREINKEL N INTERNAL STANDARDS IN ESTIMATION OF ACETYL-COA IN LIVER EXTRACTS	24	0
4451	8	9377 1994 TOXICOLOGY IN VITRO 8(6):1167-1175 HERRERO ME; CASTELL JV QUANTIFICATION OF CYP1A1 AND 2B1/2 IN RAT HEPATOCYTES CULTURED IN MICROWELLS BY IMMUNOLOGICAL METHODS	6	2
4452	4	12202 2000 ONCOGENE 19(21):2585-2597 Herrington J; Smit LS; Schwartz J; Carter-Su C The role of STAT proteins in growth hormone signaling	29	0
4453	11	2461 1974 BIOCHIMICA ET BIOPHYSICA ACTA 344(2):157-203 HERSEY SJ INTERACTIONS BETWEEN OXIDATIVE-METABOLISM AND ACID SECRETION IN GASTRIC-MUCOSA	73	0
4454	1	1519 1971 BIOCHEMISTRY 10(15):2884-& HERSH LB RAT LIVER OMEGA-AMIDASE - PURIFICATION AND PROPERTIES	48	2
4455	2	1629 1971 JOURNAL OF BIOLOGICAL CHEMISTRY 246(22):6803-& HERSH LB 5-HYDROXY-N-METHYLPYROGLUTAMATE SYNTHETASE - EVIDENCE FOR AN ALPHA-KETOGLUTARYL ENZYME INTERMEDIATE FROM PARTITIONING STUDIES	3	0
4456	1	1450 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 145(1):115-& HERSH LB; PETERSON JA; THOMPSON AA N-METHYL GLUTAMATE DEHYDROGENASE FROM PSEUDOMONAS-MA	31	0
4457	5	4004 1980 BERICHTE DER BUNSEN-GESELLSCHAFT-PHYSICAL CHEMISTRY CHEMICAL PHYSICS 84(4):346-351 HESS B; BOITEUX A OSCILLATIONS IN BIOCHEMICAL SYSTEMS	20	1
4458	29	1432 1971 ANNUAL REVIEW OF BIOCHEMISTRY 40():237-& HESS B; BOITEWX A OSCILLATORY PHENOMENA IN BIOCHEMISTRY	352	21
4459	2	206 1963 BIOCHEMISCHE ZEITSCHRIFT 338():376-& HESS B; BRAND K UBER DIE WIRKUNG VON SCHILDDRUSENHORMON AUF DIE ATMUNGSKETTE	4	0
4460	6	519 1966 HELGOLANDER WISSENSCHAFTLICHE MEERESUNTERSUCHUNGEN 14(1-4):129-& HESS B; BRAND K CONTROL MECHANISM OF GLYCOLYSIS	4	1
4461	4	279 1964 BERICHTE DER BUNSEN-GESELLSCHAFT FUR PHYSIKALISCHE CHEMIE 68(8-9):768-& HESS B; CHANCE B; BETZ A ISOLIERUNG EINES OSZILLIERENDEN SYSTEMS AUS S. CARLSBERGENSIS	18	11
4462	1	142 1961 NATURE 191(478):718-& HESS R; PEARSE AGE HISTOCHEMICAL AND HOMOGENIZATION STUDIES OF MITOCHONDRIAL ALPHA-GLYCEROPHOSPHATE DEHYDROGENASE IN NERVOUS SYSTEM	39	7
4463	7	3285 1977 BIOCHEMICAL PHARMACOLOGY 26(21):2043-2047 HESSE S; WOLFF T INVITRO INTERACTIONS OF DI-CHLOROBIPHENYL,TETRA-CHLOROBIPHENYL AND HEXA-CHLOROBIPHENYL WITH RABBIT LIVER MONOOXYGENASE	18	3
4464	5	5478 1985 PHARMACOLOGY 30(5):266-272 HEUSNER JJ; FRANKLIN MR INHIBITION OF METABOLISM OF THE NONCLASSICAL ANTIFOLATE, TRIMETREXATE (2,4-DIAMINO-5-METHYL-6-[(3,4,5-TRIMETHOXY- ANILINO)METHYL]QUINAZOLINE)BY DRUGS CONTAINING AN IMIDAZOLE MOIETY	9	4
4465	8	1222 1970 BIOCHEMICAL JOURNAL 117(5):833-& HEWICK DS; FOUTS JR METABOLISM IN-VITRO AND HEPATIC MICROSOMAL INTERACTIONS OF SOME ENANTIOMERIC DRUG SUBSTRATES	36	13
4466	5	2108 1973 BIOCHEMICAL PHARMACOLOGY 22(13):1653-1659 HEWICK DS; YOUNG CK STEREOSELECTIVE INHIBITION OF STEROID 11 BETA-HYDROXYLATION IN OX AND SHEEP ADRENOCORTICAL-MITOCHONDRIA - COMPARISON OF METYRAPONE AND ENANTIOMERS OF 2-(4-AMINOPHENYL)-2- PHENETHYLAMINE (SKF 12185)	0	0
4467	12	12274 2000 XENOBIOTICA 30(7):665-681 Hewitt NJ; Fischer T; Zuehlke U; Oesch F; Utesch D Metabolic activity of fresh and cryopreserved cynomolgus monkey (Macaca fascicularis) hepatocytes	2	0
4468	2	4113 1980 FIZIOLOGIYA I BIOKHIMIYA KULTURNYKH RASTENII 12(1):3-23 HEWITT S; HILLMAN JR STEROIDAL ESTROGENS IN PLANTS	0	0
4469	2	4189 1980 NEW PHYTOLOGIST 85(3):329-350 HEWITT S; HILLMAN JR; KNIGHTS BA STEROIDAL ESTROGENS AND PLANT-GROWTH AND DEVELOPMENT	23	0
4470	2	223 1963 BIOCHIMICA ET BIOPHYSICA ACTA 78(4):762-& HEYMANBLANCHET T ACTION DE DIFFERENTS AGENTS REDUCTEURS SUR LE SPECTRE, A BASSE TEMPERATURE, DE FRACTIONS SUBCELLULAIRES DE LEVURE	3	3
4471	2	296 1964 BIOCHIMICA ET BIOPHYSICA ACTA 81(3):462-& HEYMANBLANCHET T; OHANIANC.L; CHAIX P EVOLUTION DE LA SYNTHESE DU SYSTEME RESPIRATOIRE CHEZ LES LEVURES RECOLTEES A DIFFERENTS STADES DE LEUR CROISSANCE ANAEROBIE	18	3
4472	21	11166 1998 DRUG METABOLISM AND DISPOSITION 26(3):207-215 Hickman D; Wang JP; Wang Y; Unadkat JD Evaluation of the selectivity of in vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities	62	11
4473	2	548 1966 JOURNAL OF CELLULAR PHYSIOLOGY 68(2):185-& HIDALGO C; CANESSAF.M SODIUM TRANSPORT INHIBITION BY SELECTIVE MITOCHONDRIAL INHIBITORS IN URINARY BLADDER OF TOAD	7	0
4474	16	12213 2000 PHARMACOLOGY & THERAPEUTICS 85(1):11-28 Hiemke C; Hartter S Pharmacokinetics of selective serotonin reuptake inhibitors	47	1
4475	3	12218 2000 PHARMACOTHERAPY 20(3):280-291 Higa GM Altering the estrogenic milieu of breast cancer with a focus on the new aromatase inhibitors	1	0
4476	9	11086 1998 BRITISH JOURNAL OF HAEMATOLOGY 103(4):922-930 Higasa K; Manabe J; Yubisui T; Sumimoto H; Pung-amritt P; Tanphaichitr VS; Fukumaki Y Molecular basis of hereditary methaemoglobinaemia, types I and II: two novel mutations in the NADH-cytochrome b(5) reductase gene	7	2
4477	14	6288 1988 MUTATION RESEARCH 197(2):273-288 HIGASHI K METABOLIC-ACTIVATION OF ENVIRONMENTAL CHEMICALS BY MICROSOMAL- ENZYMES OF HIGHER-PLANTS	41	3
4478	4	1266 1970 BIOCHIMICA ET BIOPHYSICA ACTA 216(2):274-& HIGASHI S; KAWAI K PROPERTIES AND FUNCTION OF RESPIRATORY CHAIN OF FRESHWATER MUSSEL SPERMATOZOA IN RELATION TO MOTILITY	2	1
4479	2	338 1964 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 51(6):989-& HIGGINS J CHEMICAL MECHANISM FOR OSCILLATION OF GLYCOLYTIC INTERMEDIATES IN YEAST CELLS	138	48
4480	6	675 1967 INDUSTRIAL AND ENGINEERING CHEMISTRY 59(5):18-& HIGGINS J THEORY OF OSCILLATING REACTIONS	120	13
4481	8	11044 1998 BIOCHEMISTRY 37(19):7039-7046 Higgins L; Bennett GA; Shimoji M; Jones JP Evaluation of cytochrome P450 mechanism and kinetics using kinetic deuterium isotope effects	13	1
4482	3	3020 1976 BIOCHIMICA ET BIOPHYSICA ACTA 449(1):10-22 HIGUTI T; SATO M; MIZUNO S; YOKOTA M; SUGIYAMA Y; NISHITANI Y; SEKIYA M; TANI I ENERGIZATION OF MITOCHONDRIAL INNER MEMBRANES CAUSED BY L- MALATE	12	0
4483	2	5291 1985 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 130(1):396-406 HILDEBRAND CE; GONZALEZ FJ; KOZAK CA; NEBERT DW REGIONAL LINKAGE ANALYSIS OF THE DIOXIN-INDUCIBLE P-450 GENE FAMILY ON MOUSE CHROMOSOME-9	36	18
4484	0	1397 1970 PHARMACOLOGIST 12(2):261-& HILDEBRANDT A; ESTABROOK RW ON MECHANISM OF INHIBITORY ACTIONS OF SKF525A AND METYRAPONE (MP) ON HEPATIC MICROSOMAL DRUG METABOLISM	2	2
4485	10	1441 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 143(1):66-& HILDEBRANDT A; ESTABROOK RW EVIDENCE FOR PARTICIPATION OF CYTOCHROME B5 IN HEPATIC MICROSOMAL MIXED-FUNCTION OXIDATION REACTIONS	440	439
4486	8	775 1968 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 30(6):607-& HILDEBRANDT A; REMMER H; ESTABROOK RW CYTOCHROME P-450 OF LIVER MICROSOMES - 1 PIGMENT OR MANY	218	218
4487	4	1484 1971 BIOCHEMICAL JOURNAL 125(2):P6-& HILDEBRANDT AG BINDING OF METYRAPONE TO CYTOCHROME-P-450 AND ITS INHIBITORY ACTION ON LIVER MICROSOMAL MIXED-FUNCTION OXIDASE REACTIONS	7	0
4488	0	1309 1970 FEDERATION PROCEEDINGS 29(2):A738-& HILDEBRANDT AG; ESTABROOK RW DPNH AND IONIC STRENGTH AS POSITIVE EFFECTORS OF MICROSOMAL MIXED FUNCTION OXIDATIONS	0	0
4489	4	1561 1971 CHEMICO-BIOLOGICAL INTERACTIONS 3(4):276-& HILDEBRANDT AG; FRANKLIN MR; ROOTS I; ESTABROOK RW INHIBITORY EFFECT OF METYRAPONE ON CYTOCHROME P-450-CATALYZED MIXED-FUNCTION OXIDATION REACTIONS AS COMPARED TO EFFECT OF CARBON MONOXIDE	4	4
4490	5	991 1969 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 37(3):477-& HILDEBRANDT AG; LEIBMAN KC; ESTABROOK RW METYRAPONE INTERACTION WITH HEPATIC MICROSOMAL CYTOCHROME P-450 FROM RATS TREATED WITH PHENOBARBITAL	115	115
4491	1	1154 1969 PHARMACOLOGIST 11(2):250-& HILDEBRANDT AG; LEIBMAN KC; ESTABROOK RW EFFECT OF METYRAPONE ON REDUCTION OF CYTOCHROME P-450 IN RAT LIVER MICROSOMES	1	1
4492	7	2677 1975 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 171(2):385-397 HILDEBRANDT AG; ROOTS I REDUCED NICOTINAMIDE ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH)- DEPENDENT FORMATION AND BREAKDOWN OF HYDROGEN-PEROXIDE DURING MIXED-FUNCTION OXIDATION REACTIONS IN LIVER-MICROSOMES	258	83
4493	4	2804 1975 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 8(5):327-336 HILDEBRANDT AG; ROOTS I; SPECK M; SAALFRANK K; KEWITZ H EVALUATION OF INVIVO PARAMETERS OF DRUG-METABOLIZING ENZYME- ACTIVITY IN MAN AFTER ADMINISTRATION OF CLEMASTINE, PHENOBARBITAL OR PLACEBO	74	1
4494	5	2087 1973 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 54(3):968-975 HILDEBRANDT AG; SPECK M; ROOTS I POSSIBLE CONTROL OF HYDROGEN-PEROXIDE PRODUCTION AND DEGRADATION IN MICROSOMES DURING MIXED-FUNCTION OXIDATION REACTION	92	45
4495	7	2720 1975 BIOCHEMICAL SOCIETY TRANSACTIONS 3(6):807-811 HILDEBRANDT AG; TJOE M; ROOTS I MONOOXYGENASE-LINKED HYDROGEN-PEROXIDE PRODUCTION AND DEGRADATION IN LIVER MICROSOMAL FRACTIONS	18	11
4496	7	9761 1995 JOURNAL OF LIPID RESEARCH 36(12):2599-2608 Hildebrandt E; Albanesi JP; Falck JR; Campbell WB Regulation of calcium influx and catecholamine secretion in chromaffin cells by a cytochrome P450 metabolite of arachidonic acid	8	4
4497	7	6590 1989 EUROPEAN JOURNAL OF BIOCHEMISTRY 186(1-2):383-388 HILDEBRANDT P; GARDA H; STIER A; BACHMANOVA GI; KANAEVA IP; ARCHAKOV AI PROTEIN PROTEIN INTERACTIONS IN MICROSOMAL CYTOCHROME-P-450 ISOZYME LM2 AND THEIR EFFECT ON SUBSTRATE BINDING	16	5
4498	14	8996 1994 BIOCHEMISTRY 33(43):12920-12929 HILDEBRANDT P; HEIBEL G; ANZENBACHER P; LANGE R; KRUGER V; STIER A CONFORMATIONAL-ANALYSIS OF MITOCHONDRIAL AND MICROSOMAL CYTOCHROME-P-450 BY RESONANCE RAMAN-SPECTROSCOPY	17	3
4499	6	863 1968 JOURNAL OF BACTERIOLOGY 95(6):2151-& HILL GC; WHITE DC RESPIRATORY PIGMENTS OF CRITHIDIA FASCICULATA	47	4
4500	5	1391 1970 NATURWISSENSCHAFTEN 57(2):69-& HILL HAO; RODER A; WILLIAMS RJ CYTOCHROME P-450 - SUGGESTIONS AS TO STRUCTURE AND MECHANISM OF ACTION	21	0

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