#	Cited nodes	Nodes / Authors	GCS	LCS
2101	4	424 1965 JOURNAL OF BIOLOGICAL CHEMISTRY 240(9):3645-& CREMONA T; KEARNEY EB STUDIES ON RESPIRATORY CHAIN-LINKED REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE .X. REACTIONS WITH SULFHYDRYL REAGENTS	23	11
2102	4	4433 1981 PERIODICUM BIOLOGORUM 83(4):415-418 CRESNAR B; BRESKVAR K; HUDNIKPLEVNIK T IRON-SULFUR PROTEINS AS A POSSIBLE COMPONENT OF NADPH- CYTOCHROME-C REDUCTASE FROM RHIZOPUS-NIGRICANS	4	1
2103	7	5295 1985 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 133(3):1057-1063 CRESNAR B; BRESKVAR K; HUDNIKPLEVNIK T RESOLUTION AND RECONSTITUTION OF THE NADPH-CYTOCHROME-C (P-450) REDUCTASE INDUCED BY PROGESTERONE IN RHIZOPUS NIGRICANS	13	3
2104	3	11815 1999 PHARMACEUTICAL SCIENCE & TECHNOLOGY TODAY 2(3):119-120 Crespi CL Assessing the potential for drug-drug interactions in an accelerated throughput mode	6	0
2105	3	6515 1989 CARCINOGENESIS 10(2):295-301 CRESPI CL; LANGENBACH R; RUDO K; CHEN YT; DAVIES RL TRANSFECTION OF A HUMAN CYTOCHROME-P-450 GENE INTO THE HUMAN- LYMPHOBLASTOID CELL-LINE, AHH-1, AND USE OF THE RECOMBINANT CELL-LINE IN GENE MUTATION ASSAYS	63	18
2106	11	10857 1997 PHARMACOGENETICS 7(3):203-210 Crespi CL; Miller VP The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase	61	11
2107	24	11825 1999 PHARMACOLOGY & THERAPEUTICS 84(2):121-131 Crespi CL; Miller VP The use of heterologously expressed drug metabolizing enzymes - state of the art and prospects for the future	20	3
2108	3	2582 1974 LIFE SCIENCES 14(5):861-872 CRESS CR; STROTHER A EFFECTS ON DRUG-METABOLISM OF CARBARYL AND 1-NAPHTHOL IN MOUSE	14	3
2109	8	11227 1998 FOOD ADDITIVES AND CONTAMINANTS 15():45-51 Cresteil T Onset of xenobiotic metabolism in children: toxicological implications	25	2
2110	4	9016 1994 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1208(1):111-117 CRESTEIL T; MARIE S; SONNIER M; KERSUAL J; GONZALEZ FJ EVIDENCE FOR THE TRANSIENT EXPRESSION OF P-450 DURING THE NEONATAL-PERIOD IN RAT	1	1
2111	12	9031 1994 CANCER RESEARCH 54(2):386-392 CRESTEIL T; MONSARRAT B; ALVINERIE P; TRELUYER JM; VIEIRA I; WRIGHT M TAXOL METABOLISM BY HUMAN LIVER-MICROSOMES - IDENTIFICATION OF CYTOCHROME-P450 ISOZYMES INVOLVED IN ITS BIOTRANSFORMATION	131	30
2112	5	7981 1992 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 34(3):262-265 CREWE HK; LENNARD MS; TUCKER GT; WOODS FR; HADDOCK RE THE EFFECT OF SELECTIVE SEROTONIN REUPTAKE INHIBITORS ON CYTOCHROME-P4502D6 (CYP2D6) ACTIVITY IN HUMAN LIVER-MICROSOMES	342	40
2113	16	9613 1995 DRUG METABOLISM AND DISPOSITION 23(3):406-414 CRIBB AE; SPIELBERG SP; GRIFFIN GP N-4-HYDROXYLATION OF SULFAMETHOXAZOLE BY CYTOCHROME-P450 OF THE CYTOCHROME P4502C SUBFAMILY AND REDUCTION OF SULFAMETHOXAZOLE HYDROXYLAMINE IN HUMAN AND RAT HEPATIC MICROSOMES	70	11
2114	1	11323 1998 MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS 62(3):807-+ Crickmore N; Zeigler DR; Feitelson J; Schnepf E; Van Rie J; Lereclus D; Baum J; Dean DH Revision of the nomenclature for the Bacillus thuringiensis pesticidal crystal proteins	134	0
2115	6	1011 1969 BIOCHEMISTRY 8(1):322-& CRIDDLE RS; SCHATZ G PROMITOCHONDRIA OF ANAEROBICALLY GROWN YEAST .I. ISOLATION AND BIOCHEMICAL PROPERTIES	197	15
2116	2	8367 1993 AMERICAN JOURNAL OF GASTROENTEROLOGY 88(4):590-592 CRIPPIN JS ACETAMINOPHEN HEPATOTOXICITY - POTENTIATION BY ISONIAZID	25	2
2117	6	9648 1995 ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 14(1):1-8 CRIVELLO JF; SCHULTZ RJ GENETIC-VARIATION IN THE TEMPERATURE-DEPENDENCE OF LIVER MICROSOMAL CYP2E1 ACTIVITY, WITHIN AND BETWEEN SPECIES OF THE VIVIPAROUS FISH POECILIOPSIS	6	0
2118	24	11100 1998 CANCER TREATMENT REVIEWS 24(5):345-366 Crommentuyn KML; Schellens JHM; van den Berg JD; Beijnen JH In-vitro metabolism of anti-cancer drugs, methods and applications: paclitaxel, docetaxel, tamoxifen and ifosfamide	13	0
2119	5	4413 1981 JOURNAL OF PHARMACY AND PHARMACOLOGY 33(5):309-312 CROOKS PA; DAMANI LA; COWAN DA SYNTHESIS OF N-OXIDE DERIVATIVES OF METYRAPONE AND THEIR DETECTION AS INVITRO METABOLITES	13	1
2120	13	7447 1991 BIOCHIMICA ET BIOPHYSICA ACTA 1057(3):281-298 CROSS AR; JONES OTG ENZYMATIC MECHANISMS OF SUPEROXIDE PRODUCTION	288	0
2121	2	1996 1972 PHYTOCHEMISTRY 11(10):2937-& CROTEAU R; BURBOTT AJ; LOOMIS WD APPARENT ENERGY DEFICIENCY IN MONO-TERPENE AND SESQUI-TERPENE BIOSYNTHESIS IN PEPPERMINT	59	0
2122	4	2673 1975 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 170(1):61-72 CROTEAU R; KOLATTUKUDY PE BIOSYNTHESIS OF HYDROXYFATTY ACID POLYMERS - ENZYMATIC EPOXIDATION OF 18-HYDROXYOLEIC ACID TO 18-HYDROXY-CIS-9,10- EPOXYSTEARIC ACID BY A PARTICULATE PREPARATION FROM SPINACH (SPINACIA-OLERACEA)	36	5
2123	11	3869 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(2):408-413 CROWDER RD; BRADY DR MIXED-FUNCTION OXIDASES IN STEROL-METABOLISM - SEPARATE ROUTES FOR ELECTRON-TRANSFER FROM NADH AND NADPH	9	1
2124	1	3465 1977 XENOBIOTICA 7(6):345-356 CROWE CA; CALDER IC; MADSEN NP; FUNDER CC; GREEN CR; HAM KN; TANGE JD EXPERIMENTAL-MODEL OF ANALGESIC-INDUCED RENAL DAMAGE SOME EFFECTS OF PARA-AMINOPHENOL ON RAT-KIDNEY MITOCHONDRIA	25	0
2125	8	9619 1995 DRUG METABOLISM AND DISPOSITION 23(8):786-793 CROWLEY JR; HOLLENBERG PF MECHANISM-BASED INACTIVATION OF RAT-LIVER CYTOCHROME P4502B1 BY PHENCYCLIDINE AND ITS OXIDATIVE PRODUCT, THE IMINIUM ION	12	4
2126	3	6226 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(7):3348-3353 CRUSE I; MAINES MD EVIDENCE SUGGESTING THAT THE 2 FORMS OF HEME OXYGENASE ARE PRODUCTS OF DIFFERENT GENES	156	5
2127	6	9108 1994 EUROPEAN JOURNAL OF BIOCHEMISTRY 219(1-2):441-448 CSUKAI M; MURRAY M; ORR E ISOLATION AND COMPLETE SEQUENCE OF CBR, A GENE ENCODING A PUTATIVE CYTOCHROME-B REDUCTASE IN SACCHAROMYCES-CEREVISIAE	8	2
2128	4	5941 1987 LIFE SCIENCES 41(17):2047-2054 CUELLAR A; CARABEZ A; CHAVEZ E CA-2+ RELEASING EFFECT OF PEREZONE ON ADRENAL-CORTEX MITOCHONDRIA	2	0
2129	7	5934 1987 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 28(4):437-440 CUELLAR A; DIAZSANCHEZ V; ALTAMARANO A IMPAIRED PREGNENOLONE BIOSYNTHESIS IN ADRENAL-CORTEX MITOCHONDRIA BY ADRIAMYCIN	2	1
2130	6	7199 1990 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 37(4):581-585 CUELLAR A; DIAZSANCHEZ V; RAMIREZ J CHOLESTEROL SIDE-CHAIN CLEAVAGE AND 11-BETA-HYDROXYLATION ARE INHIBITED BY GOSSYPOL IN ADRENAL-CORTEX MITOCHONDRIA	4	1
2131	5	5037 1984 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 235(2):538-543 CUELLAR A; ESCAMILLA E; RAMIREZ J; CHAVEZ E ADRIAMYCIN AS AN INHIBITOR OF 11-BETA-HYDROXYLASE ACTIVITY IN ADRENAL-CORTEX MITOCHONDRIA	5	3
2132	12	12881 2002 JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS 47(3):143-151 Cui X; Palamanda J; Norton L; Thomas A; Lau YY; White RE; Cheng KC A high-throughput cell-based reporter gene system for measurement of CYP1A1 induction	0	0
2133	14	12819 2002 GENE 297(1-2):179-187 Cui XM; Strobel HW Cloning and characterization of the rat cytochrome P4504F5 (CYP4F5) gene	0	0
2134	2	12807 2002 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 27(2):107-111 Cui ZF; He P; Luo M; Xia SQ; Wu MC Phenacetin O-deethylation in extrahepatic tissues of rats	0	0
2135	10	7891 1992 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 184(3):1490-1495 CULLIN C 2 DISTINCT SEQUENCES CONTROL THE TARGETING AND ANCHORING OF THE MOUSE P450 1A1 INTO THE YEAST ENDOPLASMIC-RETICULUM MEMBRANE	13	8
2136	6	6205 1988 GENE 65(2):203-217 CULLIN C; POMPON D SYNTHESIS OF FUNCTIONAL-MOUSE CYTOCHROME-P-450-P1 AND CHIMERIC CYTOCHROME-P-450-P3-1 IN THE YEAST SACCHAROMYCES-CEREVISIAE	123	40
2137	1	5990 1987 TRANSACTIONS OF THE INSTITUTE OF BRITISH GEOGRAPHERS 12(1):57-72 CULLING WEH EQUIFINALITY - MODERN APPROACHES TO DYNAMIC-SYSTEMS AND THEIR POTENTIAL FOR GEOGRAPHICAL THOUGHT	25	0
2138	2	401 1965 CANADIAN JOURNAL OF BOTANY 43(7):825-& CUMMING BG; HENDRICK.SB; BORTHWIC.HA RHYTHMIC FLOWERING RESPONSES AND PHYTOCHROME CHANGES IN A SELECTION OF CHENOPODIUM RUBRUM	92	1
2139	6	751 1968 ANNUAL REVIEW OF PLANT PHYSIOLOGY 19():381-& CUMMING BG; WAGNER E RHYTHMIC PROCESSES IN PLANTS	81	4
2140	3	1230 1970 BIOCHEMICAL PHARMACOLOGY 19():973-& CUMMING JF; MANNERIN.GJ EFFECT OF PHENOBARBITAL ADMINISTRATION ON OXYGEN REQUIREMENT FOR HEXOBARBITAL METABOLISM IN ISOLATED, PERFUSED RAT LIVER AND IN INTACT RAT	46	7
2141	3	1655 1971 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 178(3):595-& CUMMING JF; MCCLUNG HW; MANNERIN.GJ EFFECT OF HEMORRHAGE ON RATE OF HEXOBARBITAL BIOTRANSFORMATION IN DOG	15	3
2142	11	12159 2000 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 293(2):677-685 Cummings BS; Lasker JM; Lash LH Expression of glutathione-dependent enzymes and cytochrome P450s in freshly isolated and primary cultures of proximal tubular cells from human kidney	9	1
2143	18	11607 1999 DRUG METABOLISM AND DISPOSITION 27(4):542-548 Cummings BS; Zangar RC; Novak RF; Lash LH Cellular distribution of cytochromes P-450 in the rat kidney	11	3
2144	3	5348 1985 CANCER RESEARCH 45(11):5617-5624 CUMMINGS SW; ANSARI GAS; GUENGERICH FP; CROUCH LS; PROUGH RA METABOLISM OF 3-TERT-BUTYL-4-HYDROXYANISOLE BY MICROSOMAL FRACTIONS AND ISOLATED RAT HEPATOCYTES	67	6
2145	1	729 1967 RADIATION RESEARCH 30(3):557-& CUMMINS JT; KOHL HH; VAUGHAN BE EFFECT OF RADIATION ON SOME FUNCTIONAL AND METABOLIC PARAMETERS OF ISOLATED RAT STOMACH IN COMPARISON TO SPLEEN CHANGES	3	0
2146	7	3319 1977 CHEMICO-BIOLOGICAL INTERACTIONS 16(1):23-38 CUMPS J; RAZZOUK C; ROBERFROID MB MICHAELIS-MENTEN KINETIC-ANALYSIS OF HEPATIC MICROSOMAL BENZPYRENE HYDROXYLASE FROM CONTROL, PHENOBARBITAL-TREATED AND METHYL-3-CHOLANTHRENE-TREATED RATS	38	6
2147	6	397 1965 BIOCHIMICA ET BIOPHYSICA ACTA 110(2):265-& CUNNINGH.WP; CRANE FL; SOTTOCAS.GL RELATION BETWEEN STRUCTURE AND FUNCTION IN ELECTRON-TRANSPORT SYSTEMS .I. SEQUENTIAL RELEASE OF NICOTINAMIDE-ADENINE DINUCLEOTIDE DEHYDROGENASE ACTIVITY BY A SERIES OF PHYSICAL TREATMENTS	17	0
2148	1	10959 1998 ANNUAL REVIEW OF PLANT PHYSIOLOGY AND PLANT MOLECULAR BIOLOGY 49():557-583 Cunningham FX; Gantt E Genes and enzymes of carotenoid biosynthesis in plants	94	0
2149	4	3340 1977 DRUG METABOLISM AND DISPOSITION 5(2):205-210 CUNNINGHAM RF; PEREL JM; ISRAILI ZH; DAYTON PG PROBENECID METABOLISM INVITRO WITH RAT, MOUSE, AND HUMAN LIVER PREPARATIONS - STUDIES OF FACTORS AFFECTING SITE OF OXIDATION	9	0
2150	18	6243 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(33):17418-17421 CUPP JR; VICKERY LE IDENTIFICATION OF FREE AND [FE2S2]-BOUND CYSTEINE RESIDUES OF ADRENODOXIN	33	5
2151	11	6629 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264(3):1602-1607 CUPP JR; VICKERY LE ADRENODOXIN WITH A COOH-TERMINAL DELETION (DES-116-128) EXHIBITS ENHANCED ACTIVITY	24	6
2152	11	10945 1998 AMERICAN FAMILY PHYSICIAN 57(1):107-116 Cupp MJ; Tracy TS Cytochrome P450: New nomenclature and clinical implications	19	2
2153	5	10363 1996 NATURE STRUCTURAL BIOLOGY 3(7):632-637 CuppVickery JR; Han O; Hutchinson CR; Poulos TL Substrate-assisted catalysis in cytochrome P450eryF	34	12
2154	25	9248 1994 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 269(1):384-392 CURIPEDROSA R; DAUJAT M; PICHARD L; OURLIN JC; CLAIR P; GERVOT L; LESCA P; DOMERGUE J; JOYEUX H; FOURTANIER G; MAUREL P OMEPRAZOLE AND LANSOPRAZOLE ARE MIXED INDUCERS OF CYP1A AND CYP3A IN HUMAN HEPATOCYTES IN PRIMARY CULTURE	91	28
2155	7	10845 1997 NATURE STRUCTURAL BIOLOGY 4(1):32-35 Curnow KM; Mulatero P; EmericBlanchouin N; AupetitFaisant B; Corvol P; Pascoe L The amino acid substitutions Ser288Gly and Val320Ala convert the cortisol producing enzyme, CYP11B1, into an aldosterone producing enzyme	33	6
2156	6	8830 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(10):4552-4556 CURNOW KM; SLUTSKER L; VITEK J; COLE T; SPEISER PW; NEW MI; WHITE PC; PASCOE L MUTATIONS IN THE CYP11B1 GENE CAUSING CONGENITAL ADRENAL- HYPERPLASIA AND HYPERTENSION CLUSTER IN EXON-6, EXON-7, AND EXON-8	78	19
2157	18	9965 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 330(1):142-152 Cvrk T; Hodek P; Strobel HW Identification and characterization of cytochrome P4501A1 amino acid residues interacting with a radiolabeled photoaffinity diazido-benzphetamine analogue	11	5
2158	28	10966 1998 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 349(1):95-104 Cvrk T; Strobel HW Photoaffinity labeling of cytochrome P4501A1 with azidocumene: Identification of cumene hydroperoxide binding region	11	3
2159	22	12317 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 385(2):290-300 Cvrk T; Strobel HW Role of LYS271 and LYS279 residues in the interaction of cytochrome P4501A1 with NADPH-cytochrome P450 reductase	4	2
2160	30	12321 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 389(1):31-40 Cvrk T; Strobel HW Role of THR501 residue in substrate binding and catalytic activity of cytochrome P4501A1	1	0
2161	6	5038 1984 ARCHIVES OF DERMATOLOGICAL RESEARCH 276(4):243-245 CZARNETZKI BM; GOERZ G; BOLSEN K; MERK H CYTOCHROME-P-450-DEPENDENT PRODUCTION OF CHEMOTACTIC ARACHIDONATE METABOLITES FROM HUMAN-NEUTROPHILS	1	1
2162	2	5364 1985 COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE III-SCIENCES DE LA VIE-LIFE SCIENCES 300(15):577-580 CZARNOCKA B; RUF J; FERRAND M; CARAYON P ANTIGENIC RELATIONSHIP BETWEEN THYROID PEROXIDASE AND THE MICROSOMAL ANTIGEN INVOLVED IN THYROID AUTOIMMUNE-DISEASES	21	0
2163	16	11890 2000 ACTA BIOCHIMICA POLONICA 47(4):1093-1105 Czekaj P Phenobarbital-induced expression of cytochrome P450 genes	0	0
2164	14	11658 1999 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 24(3):243-248 Czekaj P; Nowaczyk-Dura G Inhibiting effect of ethinylestradiol/levonorgestrel combination on microsomal enzymatic activities in rat liver and kidney	1	1
2165	1	294 1964 BIOCHIMICA ET BIOPHYSICA ACTA 79(1):46-& CZERLINSKI G; HOMMES F 2 FORMS OF REDUCED PYRIDINE NUCLEOTIDES AS REVEALED BY CHEMICAL RELAXATION	23	0
2166	6	10388 1996 PLANT MOLECULAR BIOLOGY 31(2):255-265 Czernic P; Huang HC; Marco Y Characterization of hsr201 and hsr515, two tobacco genes preferentially expressed during the hypersensitive reaction provoked by phytopathogenic bacteria	25	4
2167	3	12541 2001 JOURNAL OF ETHNOPHARMACOLOGY 77(1):31-35 Czinner E; Hagymasi K; Blazovics A; Kery A; Szoke E; Lemberkovics E The in vitro effect of Helichrysi flos on microsomal lipid peroxidation	3	0
2168	5	2165 1973 CANCER RESEARCH 33(11):2983-2986 CZYGAN P; GREIM H; GARRO AJ; HUTTERER F; SCHAFFNE.F; POPPER H; ROSENTHA.O; COOPER DY MICROSOMAL METABOLISM OF DIMETHYLNITROSAMINE AND CYTOCHROME-P- 450 DEPENDENCY OF ITS ACTIVATION TO A MUTAGEN	232	23
2169	2	2925 1975 ZEITSCHRIFT FUR GASTROENTEROLOGIE 13(4):468-473 CZYGAN P; STIEHL A TOXICITY OF SULFATED AND NON-SULFATED BILE-ACIDS	6	0
2170	9	2908 1975 TOXICOLOGY AND APPLIED PHARMACOLOGY 32(3):474-481 DACOSTA N; CASTRO JA; DECASTRO CR; DIAZGOMEZ MI; DEFERREYRA EC; DEFENOS OM MECHANISM OF DIMETHYLNITROSAMINE AND CARBON TETRACHLORIDE- INDUCED LIVER NECROSIS - SIMILARITIES AND DIFFERENCES	12	1
2171	2	5065 1984 BIOCHEMICAL SOCIETY TRANSACTIONS 12(3):465-466 DAHABRAH NS; WRIGGLESWORTH JM DIMETHYLSULFOXIDE INHIBITS ELECTRON-TRANSFER TO HEME-ALPHA-3 FROM HEME-ALPHA AND ITS ASSOCIATED COPPER IN CYTOCHROME-C OXIDASE	1	1
2172	11	7516 1991 CRITICAL REVIEWS IN TOXICOLOGY 21(5):345-372 DAHL AR; HADLEY WM NASAL CAVITY ENZYMES INVOLVED IN XENOBIOTIC METABOLISM - EFFECTS ON THE TOXICITY OF INHALANTS	110	19
2173	29	8381 1993 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 33():383-407 DAHL AR; LEWIS JL RESPIRATORY-TRACT UPTAKE OF INHALANTS AND METABOLISM OF XENOBIOTICS	10	1
2174	4	6850 1990 ARCHIVES OF TOXICOLOGY 64(5):370-376 DAHL JE; BECHER R; AARSTAD K; NILSEN OG; DYBING E SPECIES-DIFFERENCES IN SHORT-TERM TOXICITY FROM INHALATION EXPOSURE TO BROMOBENZENE	4	0
2175	3	5220 1984 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 81(5):1327-1331 DAHLIN DC; MIWA GT; LU AYH; NELSON SD N-ACETYL-PARA-BENZOQUINONE IMINE - A CYTOCHROME-P-450-MEDIATED OXIDATION-PRODUCT OF ACETAMINOPHEN	386	16
2176	3	7079 1990 FUNDAMENTAL AND APPLIED TOXICOLOGY 14(4):833-841 DAHLSTROMKING L; COUTURE J; LAMOUREUX C; VAILLANCOURT T; PLAA GL DOSE-DEPENDENT CYTOTOXICITY OF CHLORINATED HYDROCARBONS IN ISOLATED RAT HEPATOCYTES	8	2
2177	5	3197 1976 RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY 15(1):11-20 DAHMS R; GURTOO HL METABOLISM OF AFLATOXIN-B1 TO AFLATOXINS Q1, M1 AND P1 BY MOUSE AND RAT	23	0
2178	29	12510 2001 JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 15(2):90-99 Dai D; Bai R; Hodgson E; Rose RL Cloning, sequencing, heterologous expression, and ch;characterization of murine cytochrome p450 3a25*(Cyp3a25), a testosterone 6 beta-hydroxylase	6	2
2179	12	12613 2001 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 70(3):127-141 Dai D; Cao Y; Falls G; Levi PE; Hodgson E; Rose RL Modulation of mouse P450 isoforms CYP1A2, CYP2B10, CYP2E1, and CYP3A by the environmental chemicals mirex, 2,2-bis(p- chlorophenyl)-1,1-dichloroethylene, vinclozolin, and flutamide	1	1
2180	19	12618 2001 PHARMACOGENETICS 11(7):597-607 Dai D; Zeldin DC; Blaisdell JA; Chanas B; Coulter SJ; Ghanayem BI; Goldstein JA Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid	15	4
2181	30	11998 2000 CELLULAR AND MOLECULAR LIFE SCIENCES 57(3):487-499 Dai R; Pincus MR; Friedman FK Molecular modeling of mammalian cytochrome P450s	13	3
2182	15	11307 1998 JOURNAL OF PROTEIN CHEMISTRY 17(2):121-129 Dai RK; Pincus MR; Friedman FK Molecular modeling of cytochrome P450 2B1: Mode of membrane insertion and substrate specificity	15	8
2183	13	11308 1998 JOURNAL OF PROTEIN CHEMISTRY 17(7):643-650 Dai RK; Zhai SP; Wei XX; Pincus MR; Vestal RE; Friedman FK Inhibition of human cytochrome P450 1A2 by flavones: A molecular modeling study	16	5
2184	19	8493 1993 BIOCHEMISTRY 32(27):6928-6937 DAI Y; RASHBASTEP J; CEDERBAUM AI STABLE EXPRESSION OF HUMAN CYTOCHROME-P4502E1 IN HEPG2 CELLS - CHARACTERIZATION OF CATALYTIC ACTIVITIES AND PRODUCTION OF REACTIVE OXYGEN INTERMEDIATES	114	24
2185	10	12069 2000 EUROPEAN JOURNAL OF BIOCHEMISTRY 267(23):6729-6739 Daiber A; Herold S; Schoneich C; Namgaladze D; Peterson JA; Ullrich V Nitration and inactivation of cytochrome P450(BM-3) by peroxynitrite - Stopped-flow measurements prove ferryl intermediates	22	2
2186	6	12919 2002 NITRIC OXIDE, PT D 359():379-389 Daiber A; Ullrich V Peroxynitrite reactions with heme and heme-thiolate (P450) proteins	1	0
2187	16	9250 1994 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 269(3):1130-1135 DAIKH BE; LAETHEM RM; KOOP DR STEREOSELECTIVE EPOXIDATION OF ARACHIDONIC-ACID BY CYTOCHROME P-450S 2CAA AND 2C2	10	8
2188	28	9255 1994 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 271(3):1427-1433 DAIKH BE; LASKER JM; RAUCY JL; KOOP DR REGIOSELECTIVE AND STEREOSELECTIVE EPOXIDATION OF ARACHIDONIC- ACID BY HUMAN CYTOCHROMES P450 2C8 AND 2C9	43	30
2189	7	4143 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(11):5184-5189 DAILEY HA; STRITTMATTER P CHARACTERIZATION OF THE INTERACTION OF AMPHIPATHIC CYTOCHROME- B5 WITH STEARYL COENZYME-A DESATURASE AND NADPH - CYTOCHROME-P- 450 REDUCTASE	63	24
2190	4	4823 1983 BRITISH JOURNAL OF ANAESTHESIA 55(12):1217-1224 DALE O; NIELSEN K; WESTGAARD G; NILSEN OG DRUG-METABOLIZING-ENZYMES IN THE RAT AFTER INHALATION OF HALOTHANE AND ENFLURANE - DIFFERENT PATTERN OF RESPONSE IN LIVER, KIDNEY AND LUNG AND POSSIBLE IMPLICATIONS FOR TOXICITY	9	0
2191	5	10939 1998 ACTA ANAESTHESIOLOGICA SCANDINAVICA 42(9):1025-1027 Dale O; Olkkola KT Cytochrome P450, molecular biology and anaesthesia	4	1
2192	13	4779 1983 BIOCHEMICAL PHARMACOLOGY 32(4):593-601 DALET C; ANDERSSON KK; DALETBELUCHE I; BONFILS C; MAUREL P POLYAMINES AS MODULATORS OF DRUG OXIDATION REACTIONS CATALYZED BY CYTOCHROME-P-450 FROM LIVER-MICROSOMES	17	1
2193	4	6173 1988 DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY 7(1):39-46 DALET C; CLAIR P; DAUJAT M; FORT P; BLANCHARD JM; MAUREL P COMPLETE SEQUENCE OF CYTOCHROME-P450-3C CDNA AND PRESENCE OF 2 MESSENGER-RNA SPECIES WITH 3' UNTRANSLATED REGIONS OF DIFFERENT LENGTHS	42	38
2194	19	8077 1992 EUROPEAN JOURNAL OF BIOCHEMISTRY 204(2):641-648 DALETBELUCHE I; BOULENC X; FABRE G; MAUREL P; BONFILS C PURIFICATION OF 2 CYTOCHROME-P450 ISOZYMES RELATED TO CYP2A AND CYP3A-GENE FAMILIES FROM MONKEY (BABOON, PAPIO-PAPIO) LIVER- MICROSOMES - CROSS-REACTIVITY WITH HUMAN FORMS	43	18
2195	2	6580 1989 ENVIRONMENTAL RESEARCH 49(1):50-59 DALLAS CE; BADEAUX P; THEISS JC; FAIRCHILD EJ THE INFLUENCE OF INHALED FORMALDEHYDE ON RAT LUNG CYTOCHROME P450	4	0
2196	5	196 1963 ACTA PATHOLOGICA ET MICROBIOLOGICA SCANDINAVICA ():7-& DALLNER G STUDIES ON STRUCTURAL AND ENZYMIC ORGANIZATION OF MEMBRANOUS ELEMENTS OF LIVER MICROSOMES	4	0
2197	5	546 1966 JOURNAL OF CELL BIOLOGY 30(1):97-& DALLNER G; SIEKEVIT.P; PALADE GE BIOGENESIS OF ENDOPLASMIC RETICULUM MEMBRANES .2. SYNTHESIS OF CONSTITUTIVE MICROSOMAL ENZYMES IN DEVELOPING RAT HEPATOCYTE	635	50
2198	1	2978 1976 BIOCHEMICAL JOURNAL 153(2):287-295 DALTON H; LOWE DJ; PAWLIK RT; BRAY RC STUDIES BY ELECTRON-PARAMAGNETIC-RESONANCE SPECTROSCOPY ON MECHANISM OF ACTION OF XANTHINE DEHYDROGENASE FROM VEILLONELLA- ALCALESCENS	30	0
2199	3	11933 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 267(1):184-189 Dalton TP; Dieter MZ; Matlib RS; Childs NL; Shertzer HG; Genter MB; Nebert DW Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery	15	5
2200	4	8337 1992 TOXICOLOGY LETTERS 60(3):299-305 DALVI RR ALTERATIONS IN HEPATIC PHASE-I AND PHASE-II BIOTRANSFORMATION ENZYMES BY GARLIC OIL IN RATS	22	1

#	Cited nodes	Nodes / Authors	GCS	LCS
2201	3	7268 1990 PHARMACOLOGY & TOXICOLOGY 66(3):231-233 DALVI RR; MUTINGA ML COMPARATIVE-STUDIES OF THE EFFECTS ON LIVER AND LIVER MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM BY THE FUNGICIDES CAPTAN, CAPTAFOL AND FOLPET IN RATS	6	1
2202	3	7186 1990 JOURNAL OF PHARMACY AND PHARMACOLOGY 42(1):58-59 DALVI RR; TERSE PS INDUCTION OF HEPATIC-MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM BY LEVAMISOLE IN MALE-MICE	9	1
2203	4	966 1969 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 131(1):238-& DALY J; JERINA D; FARNSWOR.J; GUROFF G MIGRATION OF DEUTERIUM DURING ARYL HYDROXYLATION .2. EFFECT OF INDUCTION OF MICROSOMAL HYDROXYLASES WITH PHENOBARBITAL OR POLYCYCLIC AROMATIC HYDROCARBONS	45	19
2204	7	4108 1980 FEBS LETTERS 117():K45-K55 DALZIEL K ISOCITRATE DEHYDROGENASE AND RELATED OXIDATIVE DECARBOXYLASES	18	0
2205	9	4313 1981 BIOMEDICAL MASS SPECTROMETRY 8(6):270-277 DAMANI LA; CROOKS PA; COWAN DA METABOLISM OF METYRAPONE .2. CHROMATOGRAPHIC AND MASS-SPECTRAL PROPERTIES OF THE N-OXIDES OF METYRAPONE AND METYRAPOL	12	0
2206	9	10010 1996 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 226(3):900-905 Damon M; Fautrel A; Marc N; Guillouzo A; Corcos L Isolation of a new mouse cDNA clone: Hybrid form of cytochrome P450 2b10 and NADPH-cytochrome P450 oxidoreductase	5	4
2207	9	4411 1981 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 218(2):509-514 DANAN G; DESCATOIRE V; PESSAYRE D SELF-INDUCTION BY ERYTHROMYCIN OF ITS OWN TRANSFORMATION INTO A METABOLITE FORMING AN INACTIVE COMPLEX WITH REDUCED CYTOCHROME- P-450	101	14
2208	3	9582 1995 CHEST 108(1):182-189 DANDURAND RJ; MATTHEWS PM; ARNOLD DL; EIDELMAN DH MITOCHONDRIAL DISEASE - PULMONARY-FUNCTION, EXERCISE PERFORMANCE, AND BLOOD LACTATE LEVELS	16	7
2209	5	1267 1970 BIOCHIMICA ET BIOPHYSICA ACTA 216(2):328-& DANIEL RM ELECTRON TRANSPORT SYSTEM OF ACETOBACTER-SUBOXYDANS WITH PARTICULAR REFERENCE TO CYTOCHROME O	83	2
2210	9	8331 1992 TOXICOLOGY 74(1):19-32 DANIELS JM; MASSEY TE MODULATION OF AFLATOXIN-B1 BIOTRANSFORMATION IN RABBIT PULMONARY AND HEPATIC MICROSOMES	19	2
2211	121	12761 2002 CURRENT DRUG METABOLISM 3(6):561-597 Danielson PB The cytochrome P450 superfamily: Biochemistry, evolution and drug metabolism in humans	4	0
2212	16	10733 1997 INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 27(6):595-604 Danielson PB; Fogleman JC Isolation and sequence analysis of cytochrome P450 12B1: The first mitochondrial insect P450 with homology to 1 alpha,25 dihydroxy-D-3 24-hydroxylase	12	9
2213	15	11691 1999 INSECT MOLECULAR BIOLOGY 8(2):149-159 Danielson PB; Foster JLM; Cooper SK; Fogleman JC Diversity of expressed cytochrome P450 genes in the adult Mediterranean Fruit Fly, Ceratitis capitata	4	4
2214	9	9214 1994 JOURNAL OF CHEMICAL ECOLOGY 20(8):1893-1906 DANIELSON PB; FRANK MR; FOGLEMAN JC COMPARISON OF LARVAL AND ADULT P-450 ACTIVITY LEVELS FOR ALKALOID METABOLISM IN DESERT DROSOPHILA	10	8
2215	8	10372 1996 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 55(3):172-179 Danielson PB; Gloor SL; Roush RT; Fogleman JC Cytochrome P450-mediated resistance to isoquinoline alkaloids and susceptibility to synthetic insecticides in Drosophila	7	2
2216	5	9589 1995 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 110(4):683-688 DANIELSON PB; LETMAN JA; FOGLEMAN JC ALKALOID METABOLISM BY CYTOCHROME-P-450 ENZYMES IN DROSOPHILA- MELANOGASTER	5	3
2217	10	10880 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(20):10797-10802 Danielson PB; MacIntyre RJ; Fogleman JC Molecular cloning of a family of xenobiotic-inducible drosophilid cytochrome P450s: Evidence for involvement in host- plant allelochemical resistance	32	16
2218	4	4601 1982 EUROPEAN JOURNAL OF APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 14(2):125-129 DANILOV V; BARANOVA N; ISMAILOV A; EGOROV N THE EFFECT OF CAMPHOR ON BACTERIAL BIOLUMINESCENCE	8	2
2219	4	5464 1985 MICROBIOLOGY 54(4):468-472 DANILOV VS EFFECTS OF PHENOBARBITAL ON BACTERIAL LUCIFERASE OF PHOTOBACTERIUM-FISCHERI	0	0
2220	2	4315 1981 BIOORGANICHESKAYA KHIMIYA 7(11):1605-1626 DANILOV VS; EGOROV NS A MULTI-ENZYME MODEL FOR BACTERIAL LUCIFERASE	6	0
2221	5	5506 1985 XENOBIOTICA 15(4):271-276 DANILOV VS; ISMAILOV AD; BARANOVA NA THE INHIBITION OF BACTERIAL BIOLUMINESCENCE BY XENOBIOTICS	4	0
2222	9	5676 1986 JOURNAL OF BIOLOGICAL CHEMISTRY 261(23):728-735 DANNAN GA; GUENGERICH FP; WAXMAN DJ HORMONAL-REGULATION OF RAT-LIVER MICROSOMAL-ENZYMES - ROLE OF GONADAL-STEROIDS IN PROGRAMMING, MAINTENANCE, AND SUPPRESSION OF DELTA-4-STEROID 5-ALPHA-REDUCTASE, FLAVIN-CONTAINING MONOOXYGENASE, AND SEX-SPECIFIC CYTOCHROMES-P-450	127	0
2223	2	1529 1971 BIOCHIMICA ET BIOPHYSICA ACTA 235(1):44-& DANNER DJ; MORRISON M ISOLATION OF THYROID PEROXIDASE COMPLEX	32	23
2224	3	4680 1982 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 10(4-5):601-611 DANNERRABOVSKY J; GROSECLOSE RD STABILITY OF RAT LUNG AND LIVER MICROSOMAL CYTOCHROME-P-450 ENZYME-ACTIVITIES TO STORAGE - PURIFIED MICROSOMAL FRACTION, POSTMITOCHONDRIAL FRACTION, AND WHOLE TISSUE	23	3
2225	8	12483 2001 FARADAY DISCUSSIONS 120():261-276 Dano S; Hynne F; De Monte S; d'Ovidio F; Sorensen PG; Westerhoff H Synchronization of glycolytic oscillations in a yeast cell population	0	0
2226	1	7404 1991 BIOCHEMICAL PHARMACOLOGY 41(4):553-560 DANSETTE PM; AMAR C; VALADON P; PONS C; BEAUNE PH; MANSUY D HYDROXYLATION AND FORMATION OF ELECTROPHILIC METABOLITES OF TIENILIC ACID AND ITS ISOMER BY HUMAN LIVER-MICROSOMES - CATALYSIS BY A CYTOCHROME-P450 IIC DIFFERENT FROM THAT RESPONSIBLE FOR MEPHENYTOIN HYDROXYLATION	41	13
2227	7	1547 1971 BULLETIN DU CANCER 58(4):523-& DARDACHT.D; WERRINGLOER J; TUCHWEBE.B; KHANDEKA.JD; GARG BD; KOVACS K EFFECT OF PREGNENOLONE-16 ALPHA-CARBONITRILE ON MICROSOMAL ENZYME-ACTIVITY AND HEPATIC ULTRASTRUCTURE OF WALKER TUMOR- BEARING RATS	2	0
2228	5	5271 1985 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 236(2):585-592 DARDAS A; GAL D; BARRELLE M; SAURETIGNAZI G; STERJIADES R; PELMONT J THE DEMETHYLATION OF GUAIACOL BY A NEW BACTERIAL CYTOCHROME-P- 450	18	3
2229	7	11811 1999 PEDIATRIC RESEARCH 45(3):384-388 Dardis A; Saraco N; Rivarola MA; Belgorosky A Decrease in the expression of the 3 beta-hydroxysteroid dehydrogenase gene in human adrenal tissue during prepuberty and early puberty: Implications for the mechanism of adrenarche	8	2
2230	4	947 1969 ACTA BIOLOGICA ET MEDICA GERMANICA 23(4-5):565-& DARGEL R DNP-STIMULATED PROTON EFFLUX IN MITOCHONDRIA	0	0
2231	4	733 1968 ACTA BIOLOGICA ET MEDICA GERMANICA 21(4):433-& DARGEL R; STRACK E A CYCLE OF SWELLING AND CONTRACTION OF MITOCHONDRIA INITIATED BY ELECTRON TRANSPORT FOLLOWING L-PALMITOYL CARNITINE	2	0
2232	3	8359 1993 ACTA PAEDIATRICA 82(10):823-828 DARMIENTO FP; DIGREGORIO F; CIAFRE SA; POSCA T; LIGUORI A; NAPOLI C; COLASANTI P; CALI A; VECCHIONE R HISTOLOGICAL-FINDINGS AND EVIDENCE OF LIPID CONJUGATED DIENES AND MALONYLDIALDEHYDE IN HUMAN FETAL AORTAS	7	0
2233	3	8567 1993 CHEMICO-BIOLOGICAL INTERACTIONS 89(2-3):89-102 DARNERUD PO; TORNWALL U; BERGMAN A; BRANDT I LIVER ACCUMULATION OF 2,3,7,8-TETRACHLORO-[H-3]DIBENZOFURAN IN MICE - MODULATION BY TREATMENTS WITH POLYCHLORINATED-BIPHENYLS	4	0
2234	6	4571 1982 BRITISH JOURNAL OF ANAESTHESIA 54(1):97-101 DAROCHAREIS MGF; HIPOLITOREIS C EFFECTS OF THE INHALATION OF ENFLURANE ON HEPATIC-MICROSOMAL ENZYMATIC-ACTIVITIES IN THE RAT	5	0
2235	1	5765 1987 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 258(2):351-355 DARR D; ZARILLA KA; FRIDOVICH I A MIMIC OF SUPEROXIDE-DISMUTASE ACTIVITY BASED UPON DESFERRIOXAMINE-B AND MANGANESE(IV)	87	1
2236	3	7773 1991 PROTEIN ENGINEERING 4(6):701-708 DARWISH K; LI HY; POULOS TL ENGINEERING PROTEINS, SUBCLONING AND HYPEREXPRESSING OXIDOREDUCTASE GENES	25	6
2237	12	5419 1985 JOURNAL OF BIOCHEMISTRY 97(3):719-727 DAS J; BUSSE HG LONG-TERM OSCILLATION IN GLYCOLYSIS	14	4
2238	14	7464 1991 BIOPHYSICAL JOURNAL 60(2):369-379 DAS J; BUSSE HG ANALYSIS OF THE DYNAMICS OF RELAXATION TYPE OSCILLATION IN GLYCOLYSIS OF YEAST EXTRACTS	12	0
2239	4	10637 1997 CRITICAL REVIEWS IN TOXICOLOGY 27(3):273-297 Das M; Khanna SK Clinicoepidemiological, toxicological, and safety evaluation studies on argemone oil	20	0
2240	7	4507 1982 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 217(1):205-215 DAS M; SETH PK; DIXIT R; MUKHTAR H ARYL-HYDROCARBON HYDROXYLASE OF RAT-BRAIN MITOCHONDRIA - PROPERTIES OF, AND EFFECT OF INHIBITORS AND INDUCERS ON, ENZYME-ACTIVITY	21	3
2241	3	4341 1981 DRUG METABOLISM AND DISPOSITION 9(1):69-70 DAS M; SETH PK; MUKHTAR H NADH-DEPENDENT INDUCIBLE ARYL-HYDROCARBON HYDROXYLASE-ACTIVITY IN RAT-BRAIN MITOCHONDRIA	14	6
2242	8	835 1968 EUROPEAN JOURNAL OF BIOCHEMISTRY 4(4):519-& DAS ML; ORRENIUS S; ERNSTER L ON FATTY ACID AND HYDROCARBON HYDROXYLATION IN RAT LIVER MICROSOMES	100	47
2243	11	8022 1992 CHEMISTRY AND PHYSICS OF LIPIDS 62(3):303-310 DAS NP; SHAHI GS; MOOCHHALA SM; SATO T; SUNAMOTO J EFFECT OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) AND ITS TOXIC METABOLITES ON THE PHYSICOCHEMICAL PROPERTY OF THE LIPOSOMAL MEMBRANE IN RELATION TO THEIR CYTOCHROME-P-450 INHIBITION	4	0
2244	14	12030 2000 CURRENT SCIENCE 79(12):1665-1671 Das S; Tyagi AK; Kaur H Cancer modulation by glucosinolates: A review	0	0
2245	1	4766 1983 ATHEROSCLEROSIS 49(3):255-266 DASHTI N; ONTKO JA ALTERATIONS IN RAT SERUM-LIPIDS AND APOLIPOPROTEINS FOLLOWING CLOFIBRATE TREATMENT	17	0
2246	5	5512 1985 XENOBIOTICA 15(10):789-797 DASILVA DF; DIEHL H METABOLISM OF TETRA-ORGANO-LEAD COMPOUNDS BY RAT-LIVER MICROSOMAL MONO-OXYGENASE .3. ENZYMIC DEALKYLATION OF TETRAMETHYL LEAD COMPARED WITH TETRAETHYL LEAD	2	1
2247	7	5007 1983 XENOBIOTICA 13(10):583-590 DASILVA DF; SCHRODER U; DIEHL H METABOLISM OF TETRAORGANOLEAD COMPOUNDS BY RAT-LIVER MICROSOMAL MONO-OXYGENASE .2. ENZYMIC DEALKYLATION OF TETRAETHYL LEAD	7	2
2248	5	2950 1976 ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE 220(1):86-93 DATTA RK; JOHNSON EA; BHATTACHARJEE G; STENGER RJ INFLUENCE OF ACUTE AND CHRONIC ADMINISTRATION OF METHADONE HYDROCHLORIDE ON NADPH-CYTOCHROME C REDUCTASE AND CYTOCHROME-P- 450 OF MOUSE-LIVER MICROSOMES	3	0
2249	1	6209 1988 INDIAN JOURNAL OF MEDICAL RESEARCH 88():51-56 DATTA UK; MAITY CR HEPATIC FUNCTIONS OF ALBINO-RATS DURING LACTATION	1	0
2250	10	7562 1991 EUROPEAN JOURNAL OF BIOCHEMISTRY 200(2):501-510 DAUJAT M; CLAIR P; ASTIER C; FABRE I; PINEAU T; YERLE M; GELLIN J; MAUREL P INDUCTION, REGULATION AND MESSENGER HALF-LIFE OF CYTOCHROMES- P450 IA1, IA2 AND IIIA6 IN PRIMARY CULTURES OF RABBIT HEPATOCYTES - CYP 1A1, 1A2 AND 3A6 CHROMOSOME LOCATION IN THE RABBIT AND EVIDENCE THAT POSTTRANSCRIPTIONAL CONTROL OF GENE IA2 DOES NOT INVOLVE MESSENGER-RNA STABILIZATION	27	11
2251	25	11508 1999 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 264(2):413-418 Dauphin-Villemant C; Bocking D; Tom M; Maibeche M; Lafont R Cloning of a novel cytochrome P450 (CYP4C15) differentially expressed in the steroidogenic glands of an arthropod	6	0
2252	2	6200 1988 EXPERIENTIA 44(8):719-720 DAURIA MV; MINALE L; RICCIO R; URIARTE E MARINE EICOSANOIDS - OCCURRENCE OF 8-(R)-HETE IN THE STARFISH PATIRIA-MINIATA	9	1
2253	5	2345 1973 PREPARATIVE BIOCHEMISTRY 3(5):473-493 DAVIDSON B; NEARY JT; SCHWARTZ S; MALOOF F PARTIAL-PURIFICATION AND SOME PROPERTIES OF THYROID-PEROXIDASE SOLUBILIZED BY EXTRACTION WITH N-BUTANOL	16	10
2254	3	998 1969 BIOCHEMICAL JOURNAL 115(5):P23-& DAVIES DS CYTOCHROME P-450 AND DRUG OXIDATION	3	0
2255	1	791 1968 BIOCHEMICAL PHARMACOLOGY 17(9):1865-& DAVIES DS; GIGON PL; GILLETTE JR SEX DIFFERENCES IN KINETIC CONSTANTS FOR N-DEMETHYLATION OF ETHYLMORPHINE BY RAT LIVER MICROSOMES	102	42
2256	8	1138 1969 LIFE SCIENCES PART 1 PHYSIOLOGY AND PHARMACOLOGY AND PART 2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY 8(2P2):85-& DAVIES DS; GIGON PL; GILLETTE JR SPECIES AND SEX DIFFERENCES IN ELECTRON TRANSPORT SYSTEMS IN LIVER MICROSOMES AND THEIR RELATIONSHIP TO ETHYLMORPHINE DEMETHYLATION	129	78
2257	2	1418 1971 ACTA PHARMACOLOGICA ET TOXICOLOGICA 29():181-& DAVIES DS; THORGEIR.SS INDIVIDUAL DIFFERENCES IN PLASMA HALF-LIVES OF LIPID SOLUBLE DRUGS IN MAN	33	0
2258	11	5537 1986 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 244(1):387-392 DAVIES HW; BRITT SG; POHL LR CARBON-TETRACHLORIDE AND 2-ISOPROPYL-4-PENTENAMIDE-INDUCED INACTIVATION OF CYTOCHROME-P-450 LEADS TO HEME-DERIVED PROTEIN ADDUCTS	54	24
2259	6	5616 1986 CHEMICO-BIOLOGICAL INTERACTIONS 58(3):345-352 DAVIES HW; BRITT SG; POHL LR INACTIVATION OF CYTOCHROME-P-450 BY 2-ISOPROPYL-4-PENTENAMIDE AND OTHER XENOBIOTICS LEADS TO HEME-DERIVED PROTEIN ADDUCTS	24	9
2260	5	11813 1999 PESTICIDE SCIENCE 55(11):1043-1058 Davies J; Caseley JC Herbicide safeners: a review	11	0
2261	7	6128 1988 BIOCHIMICA ET BIOPHYSICA ACTA 964(1):28-35 DAVIES MJ DETECTION OF PEROXYL AND ALKOXYL RADICALS PRODUCED BY REACTION OF HYDROPEROXIDES WITH HEME-PROTEINS BY ELECTRON-SPIN RESONANCE SPECTROSCOPY	105	8
2262	9	6417 1989 BIOCHEMICAL JOURNAL 257(2):603-606 DAVIES MJ DETECTION OF PEROXYL AND ALKOXYL RADICALS PRODUCED BY REACTION OF HYDROPEROXIDES WITH RAT-LIVER MICROSOMAL FRACTIONS	60	4
2263	7	7076 1990 FREE RADICAL RESEARCH COMMUNICATIONS 9(3-6):251-258 DAVIES MJ ELECTRON-SPIN-RESONANCE STUDIES ON THE DEGRADATION OF HYDROPEROXIDES BY RAT-LIVER CYTOSOL	10	2
2264	3	6517 1989 CARCINOGENESIS 10(5):885-891 DAVIES RL; CRESPI CL; RUDO K; TURNER TR; LANGENBACH R DEVELOPMENT OF A HUMAN CELL-LINE BY SELECTION AND DRUG- METABOLIZING GENE TRANSFECTION WITH INCREASED CAPACITY TO ACTIVATE PROMUTAGENS	69	20
2265	3	7786 1991 TOXICOLOGY AND APPLIED PHARMACOLOGY 108(1):28-36 DAVILA JC; DAVIS PJ; ACOSTA D CHANGES IN GLUTATHIONE AND CELLULAR-ENERGY AS POTENTIAL MECHANISMS OF PAPAVERINE-INDUCED HEPATOTOXICITY INVITRO	12	0
2266	7	12933 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(4):2222-2227 Davis BB; Thompson DA; Howard LL; Morisseau C; Hammock BD; Weiss RH Inhibitors of soluble epoxide hydrolase attenuate vascular smooth muscle cell proliferation	3	0
2267	8	13110 2003 PROTEIN EXPRESSION AND PURIFICATION 30(1):43-54 Davis CA; Barber MJ Heterologous expression of enzymopenic methemoglobinemia variants using a novel NADH : cytochrome c reductase fusion protein	0	0
2268	7	12693 2002 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 400(1):63-75 Davis CA; Dhawan IK; Johnson MK; Barber MJ Heterologous expression of an endogenous rat cytochrome b(5)/cytochrome b(5) reductase fusion protein: Identification of histidines 62 and 85 as the heme axial ligands	0	0
2269	6	1654 1971 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 177(3):556-& DAVIS DC; SCHROEDE.DH; GRAM TE; REAGAN RL; GILLETTE JR COMPARISON OF EFFECTS OF HALOTHANE AND CCL4 ON HEPATIC DRUG METABOLIZING SYSTEM	33	6
2270	8	5759 1987 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 252(1):218-228 DAVIS HW; SUZUKI T; SCHENKMAN JB OXIDATION OF ESTERIFIED ARACHIDONATE BY RAT-LIVER MICROSOMES	12	3
2271	8	10070 1996 BIOMARKERS FOR AGROCHEMICALS AND TOXIC SUBSTANCES 643():169-179 Davis JA; Fry DM; Wilson BW Field application of fluorescence-based catalytic assays for measuring cytochrome P450 induction in birds	2	0
2272	3	12077 2000 FARADAY DISCUSSIONS (116):15-22 Davis JJ; Djuricic D; Lo KKW; Wallace ENK; Wong LL; Hill HAO A scanning tunnelling study of immobilised cytochrome P450(cam)	13	0
2273	5	1766 1972 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 46(6):1984-& DAVIS KA; BUTLER WL; POFF KL; HATEFI Y B-TYPE CYTOCHROMES OF BEEF HEART-MITOCHONDRIA	29	3
2274	7	9953 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 328(1):35-42 Davis SC; Sui ZH; Peterson JA; deMontellano PRO Oxidation of omega-oxo fatty acids by cytochrome P450(BM-3) (CYP102)	9	5
2275	4	898 1968 JOURNAL OF BIOLOGICAL CHEMISTRY 243(19):5153-& DAVIS WW; GARREN LD ON MECHANISM OF ACTION OF ADRENOCORTICORTICOTROPIC HORMONE - INHIBITORY SITE OF CYCLOHEXIMIDE IN PATHWAY OF STEROID BIOSYNTHESIS	98	6
2276	6	1913 1972 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 20(6):1198-& DAVISON KL; SELL JL DIELDRIN AND PARA, PARA'-DDT EFFECTS ON SOME MICROSOMAL ENZYMES OF LIVERS OF CHICKENS AND MALLARD DUCKS	16	1
2277	2	7010 1990 CYTOGENETICS AND CELL GENETICS 55(1-4):434-456 DAVISSON MT; LALLEY PA; PETERS J; DOOLITTLE DP; HILLYARD AL; SEARLE AG REPORT OF THE COMPARATIVE-SUBCOMMITTEE-FOR-HUMAN-AND-MOUSE- HOMOLOGIES	38	0
2278	5	7519 1991 CYTOGENETICS AND CELL GENETICS 58(3-4):1152-1189 DAVISSON MT; LALLEY PA; PETERS J; DOOLITTLE DP; HILLYARD AL; SEARLE AG REPORT OF THE COMPARATIVE COMMITTEE FOR HUMAN, MOUSE AND OTHER RODENTS	105	0
2279	11	11522 1999 BIOCHEMISTRY 38(2):751-761 Davydov DR; Hoa GHB; Peterson JA Dynamics of protein-bound water in the heme domain of P450BM3 studied by high-pressure spectroscopy: Comparison with P450cam and P450 2B4	8	3
2280	34	11959 2000 BIOCHEMISTRY 39(21):6489-6497 Davydov DR; Kariakin AA; Petushkova NA; Peterson JA Association of cytochromes P450 with their reductases: Opposite sign of the electrostatic interactions in P450BM-3 as compared with the microsomal 2B4 system	6	3
2281	5	4558 1982 BIOCHEMISTRY-MOSCOW 47(9):1241-1247 DAVYDOV DR; KURGANOV BI COMPARATIVE INVESTIGATION OF THE KINETICS OF THE REDUCTION OF CYTOCHROME-P-450 BY NADPH-CYTOCHROME-P-450 REDUCTASE AND DITHIONITE	0	0
2282	4	3967 1979 TRENDS IN BIOCHEMICAL SCIENCES 4(8):171-176 DAWSON AG OXIDATION OF CYTOSOLIC NADH FORMED DURING AEROBIC METABOLISM IN MAMMALIAN-CELLS	74	7
2283	4	3604 1978 FEBS LETTERS 91(2):169-172 DAWSON AG; COONEY GJ RECONSTRUCTION OF ALPHA-GLYCEROLPHOSPHATE SHUTTLE USING RAT- KIDNEY MITOCHONDRIA	9	5
2284	2	781 1968 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 32(4):579-& DAWSON AP; COX GF; SELWYN MJ AN EFFECT OF MALATE ON REDOX STATE OF A CYTOCHROME B COMPONENT IN MITOCHONDRIA FROM VARIOUS SOURCES	9	4
2285	3	993 1969 BIOCHEMICAL JOURNAL 111(1):27-& DAWSON AP; THORNE CJR PREPARATION AND SOME PROPERTIES OF L-3-GLYCEROPHOSPHATE DEHYDROGENASE FROM PIG BRAIN MITOCHONDRIA	30	16
2286	4	277 1964 ARCHIVES OF NEUROLOGY 11(4):369-& DAWSON DM; ROMANUL FCA ENZYMES IN MUSCLE .2. HISTOCHEMICAL QUANTITATIVE STUDIES	97	0
2287	1	1283 1970 CANCER RESEARCH 30(7):1918-& DAWSON JD; SAUER LA EFFECT OF DIFFERENT INCUBATION TEMPERATURES ON ADENINE NUCLEOTIDE CONTENT OF EHRLICH-LETTRE ASCITES TUMOR CELLS	3	0
2288	22	4912 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258(22):3637-3645 DAWSON JH; ANDERSSON LA; SONO M THE DIVERSE SPECTROSCOPIC PROPERTIES OF FERROUS CYTOCHROME-P- 450-CAM LIGAND COMPLEXES	54	0
2289	29	5857 1987 CHEMICAL REVIEWS 87(5):1255-1276 DAWSON JH; SONO M CYTOCHROME.P-450 AND CHLOROPEROXIDASE - THIOLATE-LIGATED HEME ENZYMES - SPECTROSCOPIC DETERMINATION OF THEIR ACTIVE-SITE STRUCTURES AND MECHANISTIC IMPLICATIONS OF THIOLATE LIGATION	268	26
2290	5	2676 1975 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 171(1):117-123 DAY DA; WISKICH JT ISOLATION AND PROPERTIES OF OUTER MEMBRANE OF PLANT MITOCHONDRIA	50	1
2291	10	4746 1983 ANNALES D ENDOCRINOLOGIE 44(1):15-28 DAZORD A MECHANISM OF ACTION OF ACTH	4	0
2292	2	3262 1977 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 76(4):1238-1246 DAZORD A; GALLET D; SAEZ JM ACTH-DEPENDENT STIMULATION OF A SPECIFIC PEPTIDE IN ADRENOCORTICAL-CELLS IN CULTURE	20	0
2293	2	3362 1977 FEBS LETTERS 83(2):307-310 DAZORD A; GALLET D; SAEZ JM PROTEIN DEGRADATION IN ADRENAL-CELLS IN CULTURE IS INHIBITED BY ACTH AND CYCLIC-AMP	10	2
2294	4	3511 1978 BIOCHEMICAL JOURNAL 176(1):233-239 DAZORD A; GALLET D; SAEZ JM EFFECT OF CORTICOTROPIN TREATMENT INVIVO ON SYNTHESIS OF A SPECIFIC ADRENAL CYTOSOLIC PROTEIN - CHARACTERIZATION BY DUAL- LABELLING TECHNIQUE AND POLYACRYLAMIDE-GEL ELECTROPHORESIS	19	4
2295	2	13112 2003 STEROIDS 68(3):235-243 de Gooyer ME; Oppers-Tiemissen HM; Leysen D; Verheul HAM; Kloosterboer HJ Tibolone is not converted by human aromatase to 7 alpha-methyl- 17 alpha-ethynylestradiol (7 alpha-MEE): Analyses with sensitive bioassays for estrogens and androgens and with LC- MSMS	0	0
2296	16	11745 1999 JOURNAL OF MEDICINAL CHEMISTRY 42(9):1515-1524 de Groot MJ; Ackland MJ; Horne VA; Alex AA; Jones BC Novel approach to predicting P450-mediated drug metabolism: Development of a combined protein and pharmacophore model for CYP2D6	54	0
2297	16	11746 1999 JOURNAL OF MEDICINAL CHEMISTRY 42(20):4062-4070 de Groot MJ; Ackland MJ; Horne VA; Alex AA; Jones BC A novel approach to predicting P450 mediated drug metabolism. CYP2D6 catalyzed N-dealkylation reactions and qualitative metabolite predictions using a combined protein and pharmacophore model for CYP2D6	42	0
2298	20	12875 2002 JOURNAL OF MEDICINAL CHEMISTRY 45(10):1983-1993 de Groot MJ; Alex AA; Jones BC Development of a combined protein and pharmacophore model for cytochrome P4502C9	6	0
2299	27	12662 2002 ADVANCED DRUG DELIVERY REVIEWS 54(3):367-383 de Groot MJ; Ekins S Pharmacophore modeling of cytochromes P450	3	0
2300	9	11287 1998 JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN 12(2):183-193 de Groot MJ; Havenith RWA; Vinkers HM; Zwaans R; Vermeulen NPE; van Lenthe JH Ab initio calculations on iron-porphyrin model systems for intermediates in the oxidative cycle of cytochrome P450s	9	0

#	Cited nodes	Nodes / Authors	GCS	LCS
2301	19	12757 2002 CURRENT DRUG METABOLISM 3(1):39-59 de Kanter R; Monshouwer M; Meijer DKF; Groothuis GMM Precision-cut organ slices as a tool to study toxicity and metabolism of xenobiotics with special reference to non-hepatic tissues	3	0
2302	2	11749 1999 JOURNAL OF NEUROSCIENCE 19(24):10843-10855 de la Houssaye BA; Mikule K; Nikolic D; Pfenninger KH Thrombin-induced growth cone collapse: Involvement of phospholipase A(2) and eicosanoid generation	6	0
2303	4	12434 2001 CURRENT OPINION IN PLANT BIOLOGY 4(3):225-233 De Luca V; Laflamme P The expanding universe of alkaloid biosynthesis	5	0
2304	9	12707 2002 BIOCHEMICAL PHARMACOLOGY 63(4):615-624 De Matteis F; Dawson SJ; Pons N; Pipino S Bilirubin and uroporphyrinogen oxidation by induced cytochrome P4501A and cytochrome P4502B - Role of polyhalogenated biphenyls of different configuration	0	0
2305	27	12915 2002 NATURAL PRODUCT REPORTS 19(4):477-493 de Montellano PRO; De Voss JJ Oxidizing species in the mechanism of cytochrome P450	6	0
2306	8	12341 2001 ATLA-ALTERNATIVES TO LABORATORY ANIMALS 29(2):179-192 De Smet K; Cavin C; Vercruysse A; Rogiers V Collagen type I gel cultures of adult rat hepatocytes as a screening induction model for cytochrome P450-dependent enzymes	1	0
2307	52	11583 1999 CLINICAL PHARMACOKINETICS 37(6):485-505 de Wildt SN; Kearns GL; Leeder JS; van den Anker JN Cytochrome P450 3A - Ontogeny and drug disposition	56	0
2308	8	3224 1977 ACTA ENDOCRINOLOGICA 84(4):780-788 DEALVARE LR; KIMURA T; SINGHAKOWINTA A; HONN KV; CHAVIN W MITOCHONDRIAL REDOX COMPONENTS OF HUMAN ADRENOCORTICAL STEROID HYDROXYLASES UNDER PHYSIOLOGICAL CONDITIONS AND IN FOCAL HYPERPLASIA OF ZONA FASCICULATA	2	0
2309	2	5612 1986 CHEMICO-BIOLOGICAL INTERACTIONS 58(1):79-94 DEAN PA; RETTIE AE; TURNBLOM SM; NAMKUNG MJ; JUCHAU MR CYTOSOLIC ACTIVATION OF HEMATIN-DEPENDENT MICROSOMAL MONOOXYGENASE ACTIVITY IN THE LUNG	5	2
2310	7	4513 1982 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 107(1):265-271 DEAN WL; GRAY RD HYDRODYNAMIC PROPERTIES OF MONOMERIC CYTOCHROME-P-450LM2 AND CYTOCHROME-P-450LM4 IN NORMAL-OCTYLGLUCOSIDE SOLUTION	11	5
2311	15	4651 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(24):4679-4685 DEAN WL; GRAY RD RELATIONSHIP BETWEEN STATE OF AGGREGATION AND CATALYTIC ACTIVITY FOR CYTOCHROME-P-450LM2 AND NADPH-CYTOCHROME-P-450 REDUCTASE	49	0
2312	2	12496 2001 HEPATOLOGY 33(4):915-924 DeAngelis RA; Kovalovich K; Cressman DE; Taub R Normal liver regeneration in p50/nuclear factor kappa B1 knockout mice	5	2
2313	2	4770 1983 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 114(2):500-504 DEBETHIZY JD; RICKERT DE SEQUENTIAL ENZYME-CATALYZED METABOLISM OF 4-NITROTOLUENE TO S- (4-NITROBENZYL)GLUTATHIONE	10	2
2314	3	5110 1984 DRUG METABOLISM AND DISPOSITION 12(1):45-50 DEBETHIZY JD; RICKERT DE METABOLISM OF NITROTOLUENES BY FRESHLY ISOLATED FISCHER-344 RAT HEPATOCYTES	22	4
2315	2	1868 1972 COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE D 274(14):2097-& DEBEY P; BALNY C ENZYME LUMINESCENCE OF HEPATOCYTIC MICROSOMES	3	2
2316	4	2153 1973 BIOCHIMIE 55(3):329-332 DEBEY P; BALNY C PRODUCTION OF SUPEROXIDE IONS IN RAT-LIVER MICROSOMES	35	17
2317	1	2239 1973 FEBS LETTERS 35(1):86-90 DEBEY P; BALNY C; DOUZOU P LOW-TEMPERATURE STUDIES OF MICROSOMAL CYTOCHROME P450 FLASH- PHOTOLYSIS EXPERIMENTS .2.	18	5
2318	1	2348 1973 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 70(9):2633-2636 DEBEY P; BALNY C; DOUZOU P ENZYME ASSAY IN MICROSOMES BELOW ZERO DEGREES	20	7
2319	8	2529 1974 FEBS LETTERS 46(1):75-77 DEBEY P; BALNY C; DOUZOU P LOW-TEMPERATURE STUDIES OF MICROSOMAL CYTOCHROME P450 - RELEASE OF OXIDIZING SPECIES	6	4
2320	8	3917 1979 MOLECULAR AND CELLULAR BIOCHEMISTRY 26(1):33-45 DEBEY P; GUNSALUS IC; DOUZOU P TESTING CO-SOLVENT CRYOENZYMOLOGY ON MULTIENZYME SYSTEMS	6	1
2321	1	8435 1993 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 196(1):355-362 DEBISE R; TOURAILLE S; DURAND R; ALZIARI S BIOCHEMICAL CONSEQUENCES OF A LARGE DELETION IN THE MITOCHONDRIAL GENOME OF A DROSOPHILA-SUBOBSCURA STRAIN	15	0
2322	2	10896 1997 REVUE NEUROLOGIQUE 153(10):547-553 Debouverie M; Wagner M; Ducrocq X; Grignon Y; Mousson B; Weber M The MNGIE syndrome in two siblings	7	0
2323	19	9506 1995 BIOCHEMICAL PHARMACOLOGY 50(12):2047-2056 Debri K; Boobis AR; Edwards RJ Distribution and induction of CYP3A1 and CYP3A2 in rat liver and extrahepatic tissues	44	21
2324	7	6463 1989 BIOCHEMISTRY 28(12):5128-5136 DECKER CJ; RASHED MS; BAILLIE TA; MALTBY D; CORREIA MA OXIDATIVE-METABOLISM OF SPIRONOLACTONE - EVIDENCE FOR THE INVOLVEMENT OF ELECTROPHILIC THIOSTEROID SPECIES IN DRUG- MEDIATED DESTRUCTION OF RAT HEPATIC CYTOCHROME-P450	27	12
2325	3	1860 1972 CHEMICO-BIOLOGICAL INTERACTIONS 5(4):255-& DECKERT FW; REMMER HK IN-VITRO INHIBITION OF RAT AND HUMAN LIVER MICROSOMAL ENZYMES BY 4-HYDROXYCOUMARIN ANTICOAGULANTS AND RELATED COMPOUNDS	7	2
2326	6	9753 1995 JOURNAL OF INHERITED METABOLIC DISEASE 18():181-213 DeCraemer D Secondary alterations of human hepatocellular peroxisomes	8	1
2327	3	563 1966 PHYSIOLOGICAL REVIEWS 46(2):323-& DEDUVE C; BAUDHUIN P PEROXISOMES (MICROBODIES AND RELATED PARTICLES)	1096	28
2328	3	148 1962 ADVANCES IN ENZYMOLOGY AND RELATED SUBJECTS OF BIOCHEMISTRY 24():291-358 DEDUVE C; WATTIAUX R; BAUDHUIN P DISTRIBUTION OF ENZYMES BETWEEN SUBCELLULAR FRACTIONS IN ANIMAL TISSUES	380	8
2329	11	5290 1985 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 128(2):650-656 DEE A; CARLSON G; SMITH C; MASTERS BS; WATERMAN MR REGULATION OF SYNTHESIS AND ACTIVITY OF BOVINE ADRENOCORTICAL NADPH-CYTOCHROME-P-450 REDUCTASE BY ACTH	19	11
2330	30	12336 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 396(1):16-24 Deeni YY; Paine MJI; Ayrton AD; Clarke SE; Chenery R; Wolf CR Expression, purification, and biochemical characterization of a human cytochrome P450CYP2D6-NADPH cytochrome P450 reductase fusion protein	4	3
2331	5	2623 1974 TOXICOLOGY AND APPLIED PHARMACOLOGY 27(3):558-568 DEFERREY.EC; CASTRO JA; DIAZGOME.MI; DACOSTA N; DECASTRO CR; DEFENOS OM PREVENTION AND TREATMENT OF CARBON-TETRACHLORIDE HEPATOTOXICITY BY CYSTEINE - STUDIES ABOUT ITS MECHANISM	28	0
2332	3	4320 1981 BRITISH JOURNAL OF EXPERIMENTAL PATHOLOGY 62(5):512-518 DEFERREYRA EC; DETORANZO EGD; DEFENOS OM; CASTRO JA STUDIES ON THE MECHANISM OF ENHANCEMENT OF CARBON-TETRACHLORIDE HEPATOTOXICITY BY TRITON WR-1339	7	0
2333	8	6594 1989 EXPERIMENTAL AND MOLECULAR PATHOLOGY 50(2):253-269 DEFERREYRA EC; VILLARRUEL MC; FERNANDEZ G; DEFENOS OM; BERNACCHI AS; DECASTRO CR; CASTRO JA FURTHER-STUDIES ON THE MECHANISM OF THE LATE PROTECTIVE EFFECTS OF PHENYLMETHYLSULFONYL FLUORIDE ON CARBON TETRACHLORIDE- INDUCED LIVER NECROSIS	4	0
2334	3	5260 1985 AGENTS AND ACTIONS 17(2):181-183 DEFEUDIS FV ENDOTHELIUM-DERIVED RELAXING FACTOR (EDRF)	1	0
2335	5	5462 1985 MEDICAL HYPOTHESES 17(4):363-374 DEFEUDIS FV MECHANISM OF ENDOTHELIUM-DEPENDENT VASORELAXATION	5	0
2336	5	5661 1986 GENERAL PHARMACOLOGY 17(1):1-4 DEFEUDIS FV STUDIES ON ENDOTHELIUM-DEPENDENT VASORELAXATION	8	0
2337	3	9290 1994 MOLECULAR & GENERAL GENETICS 242(6):699-707 DEFRANOUX N; GAISNE M; VERDIERE J FUNCTIONAL-ANALYSIS OF THE ZINC CLUSTER DOMAIN OF THE CYP1 (HAP1) COMPLEX REGULATOR IN HEME-SUFFICIENT AND HEME-DEFICIENT YEAST-CELLS	17	0
2338	5	7103 1990 JAPANESE JOURNAL OF CANCER RESEARCH 81(12):1253-1258 DEGAWA M; AGATSUMA T; HASHIMOTO Y SPECIES-DIFFERENCE AMONG EXPERIMENTAL RODENTS IN THE ACTIVITY AND INDUCTION OF CYTOCHROME-P-450 ISOZYMES FOR MUTAGENIC ACTIVATION OF CARCINOGENIC AROMATIC-AMINES	7	0
2339	8	8551 1993 CARCINOGENESIS 14(6):1091-1094 DEGAWA M; ARAI H; MIURA S; HASHIMOTO Y PREFERENTIAL INHIBITIONS OF HEPATIC P450IA2 EXPRESSION AND INDUCTION BY LEAD NITRATE IN THE RAT	14	1
2340	6	5849 1987 CARCINOGENESIS 8(12):1913-1918 DEGAWA M; HISHINUMA T; YOSHIDA H; HASHIMOTO Y SPECIES, SEX AND ORGAN DIFFERENCES IN INDUCTION OF A CYTOCHROME-P-450 ISOZYME RESPONSIBLE FOR CARCINOGEN ACTIVATION - EFFECTS OF DIETARY HEPATOCARCINOGENIC TRYPTOPHAN PYROLYSATE COMPONENTS IN MICE AND RATS	45	11
2341	8	7492 1991 CARCINOGENESIS 12(11):2151-2156 DEGAWA M; MIURA S; HASHIMOTO Y EXPRESSION AND INDUCTION OF CYTOCHROME P450 ISOZYMES IN HYPERPLASTIC NODULES OF RAT-LIVER	23	4
2342	6	6052 1988 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 152(2):843-848 DEGAWA M; NAMIKI M; MIURA S; UENO H; HASHIMOTO Y A MALE-SPECIFIC RENAL CYTOCHROME-P-450 ISOZYME(S) RESPONSIBLE FOR MUTAGENIC ACTIVATION OF 3-METHOXY-4-AMINOZAZOBENZENE IN MICE	4	0
2343	4	6518 1989 CARCINOGENESIS 10(6):1119-1122 DEGAWA M; TANIMURA S; AGATSUMA T; HASHIMOTO Y HEPATOCARCINOGENIC HETEROCYCLIC AROMATIC-AMINES THAT INDUCE CYTOCHROME-P-448 ISOZYMES, MAINLY CYTOCHROME-P-448H (P-450IA2), RESPONSIBLE FOR MUTAGENIC ACTIVATION OF THE CARCINOGENS IN RAT- LIVER	56	8
2344	6	5909 1987 JOURNAL OF BIOCHEMISTRY 101(6):1437-1445 DEGAWA M; YAMADA H; HISHINUMA T; MASUKO T; HASHIMOTO Y ORGAN SELECTIVE INDUCTION OF CYTOCHROME P-448 ISOZYMES IN THE RAT BY 2-METHOXY-4-AMINOAZOBENZENE AND 3-METHYLCHOLANTHRENE	25	11
2345	5	849 1968 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 349(4):465-& DEGKWITZ E; LUFT D; PFEIFFER U; STAUDING.H MICROSOMAL ENZYME ACTIVITY (COUMARIN HYDROXYLATION NADPH OXIDATION GLUCOSE-6-PHOSPHATASE AND ESTERASE) AND CYTOCHROME CONTENT (P-450 AND B5) IN NORMAL SCORBUTIC AND FASTING GUINEA PIGS	27	7
2346	9	1088 1969 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 350(5):547-& DEGKWITZ E; ULLRICH V; STAUDING.H; RUMMEL W METABOLISM AND CYTOCHROME P-450 BINDING SPECTRA OF (+)- AND (- )-HEXOBARBITAL IN RAT LIVER MICROSOMES	69	37
2347	2	2660 1975 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 258(SEP30):201-208 DEGKWITZ E; WALSCH S; DUBBERSTEIN M; WINTER J ASCORBIC-ACID AND CYTOCHROMES	22	0
2348	2	1134 1969 JOURNAL OF THEORETICAL BIOLOGY 22(2):238-& DEGN H; HARRISON DE THEORY OF OSCILLATIONS OF RESPIRATION RATE IN CONTINUOUS CULTURE OF KLEBSIELLA AEROGENES	33	4
2349	15	3825 1979 DRUG METABOLISM AND DISPOSITION 7(3):166-170 DEGRAEVE J; GIELEN JE; KAHL GF; TUTTENBERG KH; KAHL R; MAUME B FORMATION OF 2 METYRAPONE N-OXIDES BY RAT-LIVER MICROSOMES	20	7
2350	2	1725 1972 ANNALS OF CLINICAL RESEARCH 4(3):113-& DEGROOT LJ; NIEPOMNI.H; NAGASAKA A; HATI R MECHANISM OF THYROID-HORMONE FORMATION	6	3
2351	20	3433 1977 METABOLISM-CLINICAL AND EXPERIMENTAL 26(6):665-718 DEGROOT LJ; NIEPOMNISZCZE H BIOSYNTHESIS OF THYROID-HORMONE - BASIC AND CLINICAL ASPECTS	127	11
2352	9	10611 1997 CHEMICAL RESEARCH IN TOXICOLOGY 10(1):41-48 deGroot MJ; Bijloo GJ; Martens BJ; vanAcker FAA; Vermeulen NPE A refilled substrate model for human cytochrome P450 2D6	30	12
2353	11	10928 1997 XENOBIOTICA 27(4):357-368 DeGroot MJ; Bijloo GJ; VanAcker FAA; Guerra CF; Snijders JG; Vermeulen NPE Extension of a predictive substrate model for human cytochrome P4502D6	10	5
2354	35	10670 1997 DRUG METABOLISM REVIEWS 29(3):747-799 DeGroot MJ; Vermeulen NPE Modeling the active sites of cytochrome P450s and glutathione S-transferases, two of the most important biotransformation enzymes	19	8
2355	34	10105 1996 CHEMICAL RESEARCH IN TOXICOLOGY 9(7):1079-1091 deGroot MJ; Vermeulen NPE; Kramer JD; vanAcker FAA; denKelder GMDO A three-dimensional protein model for human cytochrome P450 2D6 based on the crystal structures of P450 101, p450 102, and P450 108	44	26
2356	2	10821 1997 MICROBIOLOGY-UK 143():1993-2001 DeGroot PWJ; Schaap PJ; VanGriensven LJLD; Visser J Isolation of developmentally regulated genes from the edible mushroom Agaricus bisporus	15	2
2357	6	6686 1989 KHIMIKO-FARMATSEVTICHESKII ZHURNAL 23(4):398-403 DEGTEREV IA; BUZUKOV AA; LEONOVA EY; ZAIKOV GE INVITRO INVOLVEMENT OF CYTOCHROME-P-450 IN MICROSOMAL OXIDATION OF EPINEPHRINE	1	0
2358	33	9869 1995 PROTEIN ENGINEERING 8(8):737-747 DEGTYARENKO KN STRUCTURAL DOMAINS OF P450-CONTAINING MONOOXYGENASE SYSTEMS	22	9
2359	16	8632 1993 FEBS LETTERS 332(1-2):1-8 DEGTYARENKO KN; ARCHAKOV AI MOLECULAR EVOLUTION OF P450 SUPERFAMILY AND P450-CONTAINING MONOOXYGENASE SYSTEMS	42	29
2360	2	10120 1996 COMPUTER APPLICATIONS IN THE BIOSCIENCES 12(3):237-240 Degtyarenko KN; Fabian P The directory of P450-containing systems on WorldWide Web	4	3
2361	14	12359 2001 BIOCHEMICAL SOCIETY TRANSACTIONS 29():139-147 Degtyarenko KN; Kulikova TA Evolution of bioinorganic motifs in P450-containing systems	4	0
2362	7	9094 1994 DRUG METABOLISM AND DISPOSITION 22(6):937-946 DEHAL SS; KUPFER D METABOLISM OF THE PROESTROGENIC PESTICIDE METHOXYCHLOR BY HEPATIC P450 MONOOXYGENASES IN RATS AND HUMANS - DUAL PATHWAYS INVOLVING NOVEL ORTHO RING-HYDROXYLATION BY CYP2B	30	9
2363	10	10087 1996 CANCER RESEARCH 56(6):1283-1290 Dehal SS; Kupfer D Evidence that the catechol 3,4-dihydroxytamoxifen is a proximate intermediate to the reactive species binding covalently to proteins	22	1
2364	11	10599 1997 CANCER RESEARCH 57(16):3402-3406 Dehal SS; Kupfer D CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liver	32	3
2365	8	5141 1984 FUNDAMENTAL AND APPLIED TOXICOLOGY 4(6):1009-1018 DEIMLING MJ; SCHNELL RC EFFECT OF MANGANESE ON THE HEPATIC-MICROSOMAL MIXED-FUNCTION OXIDASE ENZYME-SYSTEM IN THE RAT	1	0
2366	1	1938 1972 JOURNAL OF BIOLOGICAL CHEMISTRY 247(22):7232-& DEITRICH RA; ERWIN VG; COLLINS AC GENETIC INFLUENCE UPON PHENOBARBITAL-INDUCED INCREASE IN RAT- LIVER SUPERNATANT ALDEHYDE DEHYDROGENASE-ACTIVITY	82	3
2367	3	12375 2001 BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1503(3):329-340 Dejean L; Beauvoit B; Bunoust O; Fleury C; Guerin B; Rigoulet M The calorimetric-respirometric ratio is an on-line marker of enthalpy efficiency of yeast cells growing on a non-fermentable carbon source	1	0
2368	1	2223 1973 EUROPEAN JOURNAL OF BIOCHEMISTRY 32(2):356-364 DEJONGE HR; HULSMANN WC INHIBITION OF MITOCHONDRIAL-PROTEIN SYNTHESIS IN RAT SMALL- INTESTINAL EPITHELIUM	13	1
2369	10	12387 2001 BLOOD 97(4):1106-1114 Dekker J; Eppink MHM; van Zwieten R; de Rijk T; Remacha AF; Law LK; Li AM; Cheung KL; van Berkel WJH; Roos D Seven new mutations in the nicotinamide adenine dinucleotide reduced-cytochrome b(5) reductase gene leading to methemoglobinemia type I	5	2
2370	3	2742 1975 BIOCHIMICA ET BIOPHYSICA ACTA 387(3):441-450 DEKOK J; MULLER JLM; SLATER EC EPR STUDIES ON RESPIRATORY-CHAIN OF WILD-TYPE SACCHAROMYCES- CEREVISIAE AND MUTANTS WITH A DEFICIENCY IN SUCCINATE- DEHYDROGENASE	14	1
2371	4	4269 1981 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 99(1):205-212 DEKOUCHKOVSKY Y; HARAUX F (H2O)-H-2 EFFECT ON THE ELECTRON AND PROTON FLOW IN ISOLATED- CHLOROPLASTS - AN INDICATION FOR LATERAL HETEROGENEITY OF MEMBRANE PH	23	1
2372	4	4615 1982 FEBS LETTERS 139(2):245-249 DEKOUCHKOVSKY Y; HARAUX F; SIGALAT C EFFECT OF HYDROGEN-DEUTERIUM EXCHANGE ON ENERGY-COUPLED PROCESSES IN THYLAKOIDS - A NEW ILLUSTRATION OF THE HYPOTHESIS OF LOCAL PROTON GRADIENTS WITH THE ENERGY-TRANSDUCING BIOMEMBRANES	15	0
2373	2	12091 2000 GENOME RESEARCH 10(12):1958-1967 Del Punta K; Rothman A; Rodriguez I; Mombaerts P Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse	13	0
2374	2	6127 1988 BIOCHIMICA ET BIOPHYSICA ACTA 958(3):424-433 DELACLOS BF; BORGEAT P CONDITIONS FOR THE FORMATION OF THE OXO DERIVATIVES OF ARACHIDONIC-ACID FROM PLATELET 12-LIPOXYGENASE AND SOYBEAN 15- LIPOXYGENASE	18	1
2375	6	11732 1999 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 84(11):4050-4054 Deladoey J; Fluck C; Bex M; Yoshimura N; Harada N; Mullis PE Aromatase deficiency caused by a novel P450(arom) gene mutation: Impact of absent estrogen production on serum gonadotropin concentration in a boy	21	2
2376	10	5621 1986 CHEMICO-BIOLOGICAL INTERACTIONS 60(1):101-114 DELAFORGE M; BATTIONI P; MAHY JP; MANSUY D INVIVO FORMATION OF JIGMA-METHYL-FERRIC AND JIGMA-PHENYL-FERRIC COMPLEXES OF HEMOGLOBIN AND LIVER-CYTOCHROME-P-450 UPON TREATMENT OF RATS WITH METHYLHYDRAZINE AND PHENYLHYDRAZINE	23	15
2377	9	4080 1980 CHEMICO-BIOLOGICAL INTERACTIONS 32(1-2):101-110 DELAFORGE M; IOANNIDES C; PARKE DV INHIBITION OF CYTOCHROME P-448 MIXED-FUNCTION OXIDASE ACTIVITY FOLLOWING ADMINISTRATION OF 9-HYDROXYELLIPTICINE TO RATS	31	9
2378	12	4587 1982 CHEMICO-BIOLOGICAL INTERACTIONS 42(3):279-289 DELAFORGE M; IOANNIDES C; PARKE DV SELECTIVE-INHIBITION OF THE SAFROLE-INDUCED MIXED-FUNCTION OXIDASE ACTIVITIES BY 9-HYDROXYELLIPTICINE	10	5
2379	13	5507 1985 XENOBIOTICA 15(4):333-342 DELAFORGE M; IOANNIDES C; PARKE DV LIGAND-COMPLEX FORMATION BETWEEN CYTOCHROME-P-450 AND CYTOCHROME-P448 AND METHYLENEDIOXYPHENYL COMPOUNDS	12	3
2380	3	6884 1990 BIOCHEMICAL PHARMACOLOGY 40(2):223-228 DELAFORGE M; SARTORI E INVIVO EFFECTS OF ERYTHROMYCIN, OLEANDOMYCIN AND ERYTHRALOSAMINE DERIVATIVES ON HEPATIC CYTOCHROME-P-450	17	2
2381	3	7598 1991 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 32(9):2511-2514 DELAMERE NA; SOCCI RR; KING KL; BHATTACHERJEE P THE INFLUENCE OF 12(R)-HYDROXYEICOSATETRAENOIC ACID ON CILIARY EPITHELIAL SODIUM, POTASSIUM-ADENOSINE TRIPHOSPHATASE-ACTIVITY AND INTRAOCULAR-PRESSURE IN THE RABBIT	11	0
2382	7	8590 1993 DRUG METABOLISM AND DISPOSITION 21(3):520-523 DELAPORTE E; CRIBB AE; RENTON KW MODULATION OF RAT HEPATIC CYP3A1 INDUCTION BY THE INTERFERON INDUCER POLYINOSINIC ACID-POLYCYTIDYLIC ACID (POLYIC)	18	4
2383	11	9555 1995 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 73(12):1692-1697 Delaporte E; Cribb AE; Renton KW Interferon-mediated changes in the expression of CYP1A1 in human B lymphoblastoid (AHH-1 TK+/-) cells	4	2
2384	1	8162 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267(7):4513-4517 DELAUNOIT Y; ZHAO HF; BELANGER A; LABRIE F; SIMARD J EXPRESSION OF LIVER-SPECIFIC MEMBER OF THE 3-BETA- HYDROXYSTEROID DEHYDROGENASE FAMILY, AN ISOFORM POSSESSING AN ALMOST EXCLUSIVE 3-KETOSTEROID REDUCTASE-ACTIVITY	38	2
2385	2	245 1963 KLINISCHE WOCHENSCHRIFT 41(10):488-& DELBRUCK A ENZYMVERTEILUNGSMUSTER GEFASSLOSER GEWEBE	9	0
2386	2	52 1959 BIOCHEMISCHE ZEITSCHRIFT 331(4):273-296 DELBRUCK A; ZEBE E; BUCHER T UBER VERTEILUNGSMUSTER VON ENZYMEN DES ENERGIE LIEFERNDEN STOFFWECHSELS IM FLUGMUSKEL, SPRUNGMUSKEL UND FETTKORPER VON LOCUSTA MIGRATORIA UND IHRE CYTOLOGISCHE ZUORDNUNG	305	23
2387	9	8006 1992 CARCINOGENESIS 13(11):2175-2177 DELCARRATORE R; MORICHETTI E; CECCHINI E; BRONZETTI G; GALLO E; GALEOTTI CL EXPRESSION OF CYTOCHROME P450 IN YEAST AFTER DIFFERENT CHEMICAL TREATMENTS	1	0
2388	8	9537 1995 BIOELECTROMAGNETICS 16(5):324-329 DELCARRATORE R; MORICHETTI E; DELLACROCE C; BRONZETTI G EFFECT OF MAGNETIC-FIELDS ON RODENT MONOOXYGENASE ENZYMES	2	0
2389	2	3256 1977 ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH 27-1(NB6):1316-1321 DELL HD; JACOBI H; WASCHE B BIOCHEMICAL STUDIES ON ETOFENAMATE - EXPERIMENTAL TESTS IN ANIMALS	19	0
2390	3	5511 1985 XENOBIOTICA 15(7):591-597 DELMONTE M; CITTI L; GERVASI PG ISOPRENE METABOLISM BY LIVER MICROSOMAL MONOOXYGENASES	29	3
2391	16	9658 1995 EUROPEAN JOURNAL OF BIOCHEMISTRY 232(1):247-256 DELORME C; PIFFETEAU A; VIGER A; MARQUET A INHIBITION OF BOVINE CYTOCHROME P-450(11-BETA) BY 18- UNSATURATED PROGESTERONE DERIVATIVES	7	3
2392	9	11827 1999 PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY 55(6):317-326 Delserone LM; McCluskey K; Matthews DE; Vanetten HD Pisatin demethylation by fungal pathogens and nonpathogens of pea: association with pisatin tolerance and virulence	8	2
2393	7	4025 1980 BIOCHEMICAL PHARMACOLOGY 29(3):441-445 DELVIN EE; ARABIAN A; GLORIEUX FH KINETIC ALTERATIONS IN RAT-LIVER MICROSOMAL CHOLECALCIFEROL 25- HYDROXYLASE ASSOCIATED WITH PHENOBARBITAL ADMINISTRATION	6	0
2394	11	11155 1998 CURRENT GENETICS 34(5):399-403 Delye C; Bousset L; Corio-Costet MF PCR cloning and detection of point mutations in the eburicol 14 alpha-demethylase (CYP51) gene from Erysiphe graminis f. sp. hordei, a "recalcitrant" fungus	16	2
2395	9	10717 1997 GENE 195(1):29-33 Delye C; Laigret F; CorioCostet MF Cloning and sequence analysis of the eburicol 14 alpha- demethylase gene of the obligate biotrophic grape powdery mildew fungus	10	3
2396	10	1295 1970 EUROPEAN JOURNAL OF BIOCHEMISTRY 13(3):416-& DEMAILLE J; VIGNAIS PM; VIGNAIS PV FUSCIN A NEW INHIBITOR OF MITOCHONDRIAL RESPIRATION OF ANIMALS AND OF YEAST MITOCHONDRIA	7	1
2397	1	8209 1992 JOURNAL OF ORGANIC CHEMISTRY 57(19):5074-5075 DEMASTER EG; SHIROTA FN; NAGASAWA HT A BECKMANN-TYPE DEHYDRATION OF N-BUTYRALDOXIME CATALYZED BY CYTOCHROME-P-450	18	4
2398	4	2795 1975 EUROPEAN JOURNAL OF BIOCHEMISTRY 51(2):329-336 DEME D; FIMIANI E; POMMIER J; NUNEZ J FREE DIIODOTYROSINE EFFECTS ON PROTEIN IODINATION AND THYROID- HORMONE SYNTHESIS CATALYZED BY THYROID PEROXIDASE	48	15
2399	5	3084 1976 EUROPEAN JOURNAL OF BIOCHEMISTRY 70(1):7-13 DEME D; GAVARET JM; POMMIER J; NUNEZ J MAXIMAL NUMBER OF HORMONOGENIC IODOTYROSINE RESIDUES IN THYROGLOBULIN IODINATED BY THYROID PEROXIDASE	36	11
2400	7	3085 1976 EUROPEAN JOURNAL OF BIOCHEMISTRY 70(2):435-440 DEME D; POMMIER J; NUNEZ J KINETICS OF THYROGLOBULIN IODINATION AND OF HORMONE SYNTHESIS CATALYZED BY THYROID PEROXIDASE - ROLE OF IODIDE IN COUPLING REACTION	38	8

#	Cited nodes	Nodes / Authors	GCS	LCS
2401	2	7463 1991 BIOORGANICHESKAYA KHIMIYA 17(7):900-920 DEMIN PM; MYAGKOVA GI; EVSTIGNEEVA RP LIPOXYGENASE BIOSYNTHETIC PATHWAYS OF THE POLYUNSATURATED FATTY-ACID ACYCLIC METABOLITES FORMATION	3	1
2402	2	4958 1983 MATHEMATICAL BIOSCIENCES 67(1):1-17 DEMONGEOT J; LAURENT M SIGMOIDICITY IN ALLOSTERIC MODELS	1	0
2403	26	5024 1984 ANNUAL REPORTS IN MEDICINAL CHEMISTRY 19():201-211 DEMONTELLANO PRO THE INACTIVATION OF CYTOCHROME-P-450	31	6
2404	26	5230 1984 REVIEWS IN BIOCHEMICAL TOXICOLOGY 6():1-26 DEMONTELLANO PRO PROSTHETIC HEME ALKYLATION AND THE CATALYTIC MECHANISM OF CYTOCHROME-P-450	6	2
2405	10	5746 1987 ACCOUNTS OF CHEMICAL RESEARCH 20(8):289-294 DEMONTELLANO PRO CONTROL OF THE CATALYTIC ACTIVITY OF PROSTHETIC HEME BY THE STRUCTURE OF HEMOPROTEINS	215	17
2406	29	7266 1990 PHARMACOLOGY & THERAPEUTICS 48(1):95-120 DEMONTELLANO PRO FREE-RADICAL MODIFICATION OF PROSTHETIC HEME GROUPS	19	1
2407	23	9533 1995 BIOCHIMIE 77(7-8):581-593 DEMONTELLANO PRO ARYLHYDRAZINES AS PROBES OF HEMOPROTEIN STRUCTURE AND FUNCTION	23	7
2408	9	4919 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258(14):8623-8629 DEMONTELLANO PRO; AUGUSTO O; VIOLA F; KUNZE KL CARBON RADICALS IN THE METABOLISM OF ALKYL HYDRAZINES	77	17
2409	3	4391 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256(9):4395-4399 DEMONTELLANO PRO; BEILAN HS; KUNZE KL; MICO BA DESTRUCTION OF CYTOCHROME-P-450 BY ETHYLENE - STRUCTURE OF THE RESULTING PROSTHETIC HEME ADDUCT	104	18
2410	8	5441 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260(16):9265-9271 DEMONTELLANO PRO; CATALANO CE EPOXIDATION OF STYRENE BY HEMOGLOBIN AND MYOGLOBIN - TRANSFER OF OXIDIZING EQUIVALENTS TO THE PROTEIN SURFACE	142	6
2411	20	8100 1992 FASEB JOURNAL 6(2):695-699 DEMONTELLANO PRO; CHAN WK; TUCK SF; KAIKAUS RM; BASS NM; PETERSON JA MECHANISM-BASED PROBES OF THE TOPOLOGY AND FUNCTION OF FATTY- ACID HYDROXYLASES	42	20
2412	7	5916 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262(24):11641-11646 DEMONTELLANO PRO; CHOE YS; DEPILLIS G; CATALANO CE STRUCTURE-MECHANISM RELATIONSHIPS IN HEMOPROTEINS - OXYGENATIONS CATALYZED BY CHLOROPEROXIDASE AND HORSERADISH- PEROXIDASE	91	9
2413	17	4750 1983 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 23():481-503 DEMONTELLANO PRO; CORREIA MA SUICIDAL DESTRUCTION OF CYTOCHROME-P-450 DURING OXIDATIVE DRUG- METABOLISM	235	50
2414	5	4901 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258(17):558-563 DEMONTELLANO PRO; KERR DE INACTIVATION OF CATALASE BY PHENYLHYDRAZINE - FORMATION OF A STABLE ARYL-IRON HEME COMPLEX	62	0
2415	9	4549 1982 BIOCHEMISTRY 21(6):1331-1339 DEMONTELLANO PRO; KUNZE KL; BEILAN HS; WHEELER C DESTRUCTION OF CYTOCHROME-P-450 BY VINYL FLUORIDE, FLUROXENE, AND ACETYLENE - EVIDENCE FOR A RADICAL INTERMEDIATE IN OLEFIN OXIDATION	107	19
2416	6	4253 1981 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 206(1):43-50 DEMONTELLANO PRO; MICO BA DESTRUCTION OF CYTOCHROME-P-450 BY ALLYLISOPROPYLACETAMIDE IS A SUICIDAL PROCESS	86	13
2417	10	4259 1981 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 210(2):717-728 DEMONTELLANO PRO; MICO BA; MATHEWS JM; KUNZE KL; MIWA GT; LU AYH SELECTIVE INACTIVATION OF CYTOCHROME-P-450 ISOZYMES BY SUICIDE SUBSTRATES	109	25
2418	10	11139 1998 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 121(1-3):139-146 den Besten PJ Cytochrome P450 monooxygenase system in echinoderms	13	0
2419	8	9393 1994 XENOBIOTICA 24(10):989-1001 DENBESTEN PJ; LEMAIRE P; LIVINGSTONE DR NADPH-DEPENDNENT, NADH-DEPENDENT AND CUMENE HYDROPEROXIDE- DEPENDENT METABOLISM OF BENZO[A]PYRENE BY PYLORIC CECA MICROSOMES OF THE SEA-STAR, ASTERIAS-RUBENS L (ECHINODERMATA, ASTEROIDEA)	7	3
2420	8	11527 1999 BIOCHEMISTRY 38(41):13699-13706 Deng TJ; Proniewicz LM; Kincaid JR; Yeom H; Macdonald IDG; Sligar SG Resonance Raman studies of cytochrome P450BM3 and its complexes with exogenous ligands	9	2
2421	4	2319 1973 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 4(4):407-& DENICOLA AF; FREIRE F MITOCHONDRIAL 11 BETA HYDROXYLATION AND ADRENAL MORPHOLOGY IN RATS BEARING A MAMMOTROPIC, ACTH-SECRETING PITUITARY TUMOR	15	6
2422	7	8148 1992 JOURNAL OF BIOCHEMICAL TOXICOLOGY 7(4):249-256 DENISON MS HETEROGENEITY OF RAT HEPATIC AH-RECEPTOR - IDENTIFICATION OF 2 RECEPTOR FORMS WHICH DIFFER IN THEIR BIOCHEMICAL-PROPERTIES	7	1
2423	2	7224 1990 MOLECULAR AND CELLULAR ENDOCRINOLOGY 69(1):51-57 DENISON MS; DEAL RM THE BINDING OF TRANSFORMED AROMATIC HYDROCARBON (AH) RECEPTOR TO ITS DNA RECOGNITION SITE IS NOT AFFECTED BY METAL DEPLETION	42	3
2424	2	6644 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264(28):16478-16482 DENISON MS; FISHER JM; WHITLOCK JP PROTEIN-DNA INTERACTIONS AT RECOGNITION SITES FOR THE DIOXIN-AH RECEPTOR COMPLEX	132	19
2425	22	9726 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(31):18175-18178 DENISON MS; WHITLOCK JP XENOBIOTIC-INDUCIBLE TRANSCRIPTION OF CYTOCHROME-P450 GENES	142	46
2426	5	7356 1991 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 284(1):158-166 DENISON MS; YAO EF CHARACTERIZATION OF THE INTERACTION OF TRANSFORMED RAT HEPATIC CYTOSOLIC AH RECEPTOR WITH A DIOXIN RESPONSIVE TRANSCRIPTIONAL ENHANCER	46	6
2427	12	1989 1972 PATHOLOGIA EUROPAEA 7(1):43-& DENK H CHEMICAL STRUCTURE OF ENDOPLASMIC-RETICULUM AND FUNCTION OF MICROSOMAL BIOTRANSFORMATION SYSTEM OF LIVER-CELL OF RATS IN EXPERIMENTAL CHOLESTASE	15	7
2428	3	3466 1977 ZEITSCHRIFT FUR GASTROENTEROLOGIE 15(6):373-377 DENK H METABOLISM OF HYPNOTIC AND SEDATIVE DRUGS IN CHOLESTASIS	0	0
2429	29	3940 1979 PHARMACOLOGY & THERAPEUTICS 6(3):551-577 DENK H EFFECT OF DETERGENTS ON THE MIXED-FUNCTION OXIDASE AND OTHER MICROSOMAL-ENZYMES	17	4
2430	15	4070 1980 CANCER RESEARCH 40(7):2568-2573 DENK H; ABDELFATTAHGAD M; ECKERSTORFER R; TALCOTT RE MICROSOMAL MIXED-FUNCTION OXIDASE AND ACTIVITIES OF SOME RELATED ENZYMES IN HYPERPLASTIC NODULES INDUCED BY LONG-TERM GRISEOFULVIN ADMINISTRATION IN MOUSE-LIVER	13	1
2431	9	3357 1977 EXPERIMENTAL AND MOLECULAR PATHOLOGY 26(2):193-203 DENK H; ECKERSTORFER R; ROHR HP ENDOPLASMIC-RETICULUM OF RAT-LIVER CELL IN EXPERIMENTAL MECHANICAL CHOLESTASIS - CORRELATED BIOCHEMICAL AND ULTRASTRUCTURAL-MORPHOMETRIC STUDIES ON STRUCTURE AND ENZYME COMPOSITION	11	0
2432	9	3279 1977 BIOCHEMICAL PHARMACOLOGY 26(12):1125-1130 DENK H; ECKERSTORFER R; TALCOTT RE; SCHENKMAN JB ALTERATION OF HEPATIC MICROSOMAL-ENZYMES BY GRISEOFULVIN TREATMENT OF MICE	26	10
2433	6	3141 1976 JOURNAL OF CELL BIOLOGY 69(3):589-598 DENK H; MOLDEUS PW; SCHULZ RA; SCHENKMAN JB; KEYES SR; CINTI DL HEPATIC ORGANELLE INTERACTION .4. MECHANISM OF SUCCINATE ENHANCEMENT OF FORMALDEHYDE ACCUMULATION FROM ENDOPLASMIC- RETICULUM N-DEALKYLATIONS	18	3
2434	6	1585 1971 EXPERIMENTAL AND MOLECULAR PATHOLOGY 14(2):263-& DENK H; SCHENKMAN JB; BACCHIN PG; HUTTERER F; SCHAFFNE.F; POPPER H MECHANISM OF CHOLESTASIS .3. INTERACTION OF SYNTHETIC DETERGENTS WITH MICROSOMAL CYTOCHROME-P-450 DEPENDENT BIOTRANSFORMATION SYSTEM IN-VITRO - COMPARISON BETWEEN EFFECTS OF DETERGENTS, EFFECTS OF BILE ACIDS, AND FINDINGS IN BILE DUCT LIGATED RATS	42	20
2435	6	6427 1989 BIOCHEMICAL PHARMACOLOGY 38(4):603-610 DENLINGER CL; VESELL ES HORMONAL-REGULATION OF THE DEVELOPMENTAL PATTERN OF EPOXIDE HYDROLASES - STUDIES IN RAT-LIVER	9	1
2436	12	9837 1995 PHARMACOGENETICS 5(2):89-96 DENNER K; VOGEL R; SCHMALIX W; DOEHMER J; BERNHARDT R CLONING AND STABLE EXPRESSION OF THE HUMAN MITOCHONDRIAL CYTOCHROME P45011B1 CDNA IN V79 CHINESE-HAMSTER CELLS AND THEIR APPLICATION FOR TESTING OF POTENTIAL INHIBITORS	11	5
2437	11	3344 1977 DRUG METABOLISM AND DISPOSITION 6(1):96-101 DENT JG; ELCOMBE CR; NETTER KJ; GIBSON JE RAT HEPATIC MICROSOMAL CYTOCHROME(S) P-450 INDUCED BY POLYBROMINATED BIPHENYLS	1	0
2438	2	10918 1997 VETERINARY RESEARCH COMMUNICATIONS 21(5):317-323 Deoras DP; YoungCurtis P; Dalvi RR; Tippett FE Effect of gossypol on hepatic and serum gamma- glutamyltransferase activity in rats	0	0
2439	25	4496 1982 ANNALES DE MEDECINE VETERINAIRE 126(7):525-535 DEPELCHIN B CYTOCHROME-P-450 - A GROUP OF HEMOPROTEINS WHICH CATALYZE MONOOXYGENATION OF SEVERAL ENDOGENOUS AND EXOGENOUS SUBSTRATS	0	0
2440	6	9351 1994 PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS 51(4):215-229 DEPETROCELLIS L; DIMARZO V AQUATIC INVERTEBRATES OPEN UP NEW PERSPECTIVES IN EICOSANOID RESEARCH - BIOSYNTHESIS AND BIOACTIVITY	24	1
2441	1	5043 1984 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 118(2):573-579 DEPEYSTER A; QUINTANILHA A; PACKER L; SMITH MT OXYGEN RADICAL FORMATION INDUCED BY GOSSYPOL IN RAT-LIVER MICROSOMES AND HUMAN-SPERM	33	0
2442	30	2748 1975 BIOCHIMICA ET BIOPHYSICA ACTA 415(4):411-472 DEPIERRE JW; DALLNER G STRUCTURAL ASPECTS OF MEMBRANE OF ENDOPLASMIC-RETICULUM	379	55
2443	30	3238 1977 ANNUAL REVIEW OF BIOCHEMISTRY 46():201-262 DEPIERRE JW; ERNSTER L ENZYME TOPOLOGY OF INTRACELLULAR MEMBRANES	339	29
2444	48	3541 1978 BIOCHIMICA ET BIOPHYSICA ACTA 473(3-4):149-186 DEPIERRE JW; ERNSTER L METABOLISM OF POLYCYCLIC-HYDROCARBONS AND ITS RELATIONSHIP TO CANCER	199	24
2445	6	6469 1989 BIOCHEMISTRY 28(19):7947-7952 DEPILLIS GD; DEMONTELLANO PRO SUBSTRATE OXIDATION BY THE HEME EDGE OF FUNGAL PEROXIDASES - REACTION OF COPRINUS-MACRORHIZUS PEROXIDASE WITH HYDRAZINES AND SODIUM-AZIDE	38	6
2446	8	6833 1990 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 280(1):217-223 DEPILLIS GD; WARIISHI H; GOLD MH; DEMONTELLANO PRO INACTIVATION OF LIGNIN PEROXIDASE BY PHENYLHYDRAZINE AND SODIUM-AZIDE	36	6
2447	12	12863 2002 JOURNAL OF ENDOCRINOLOGY 175(3):779-792 Depreter M; Vandesompele J; Espeel M; Speleman F; Roels F Modulation of the peroxisomal gene expression pattern by dehydroepiandrosterone and vitamin D: therapeutic implications	1	0
2448	6	2151 1973 BIOCHIMICA ET BIOPHYSICA ACTA 325(3):397-405 DERIDDER JJ; KLEVERLA.NT; VERDOUWC.CV; SCHIPPER.PG; VANDAM K UNCOUPLER-STIMULATED OXIDATION OF CHOLINE BY RAT-LIVER MITOCHONDRIA	12	0
2449	5	2746 1975 BIOCHIMICA ET BIOPHYSICA ACTA 408(2):112-122 DERIDDER JJM; VANDAM K CONTROL OF CHOLINE OXIDATION BY RAT-LIVER MITOCHONDRIA	16	4
2450	2	1532 1971 BIOCHIMICA ET BIOPHYSICA ACTA 243(1):53-& DERVARTA.DV; LEGALL J ELECTRON PARAMAGNETIC RESONANCE STUDIES ON REACTION OF EXOGENOUS LIGANDS WITH CYTOCHROME C3 FROM DESULFOVIBRIO- VULGARIS	30	0
2451	1	9344 1994 PRESSE MEDICALE 23(21):991-994 DESCHAMPS F; PFOHLLESZKOWICZ A; TRENQUE T RISK FOR OCCUPATIONAL CANCERS - EFFECT OF DEOXYRIBONUCLEIC-ACID ADDUCTS	1	0
2452	4	9743 1995 JOURNAL OF DRUG TARGETING 2(6):477-485 DESJARDINS J; MATA J; BROWN T; GRAHAM D; ZON G; IVERSEN P CHOLESTERYL-CONJUGATED PHOSPHOROTHIOATE OLIGODEOXYNUCLEOTIDES MODULATE CYP2B1 EXPRESSION IN-VIVO	19	1
2453	5	9777 1995 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 275(3):1608-1613 Desjardins JP; Iversen PL Inhibition of the rat cytochrome P450 3A2 by an antisense phosphorothioate oligodeoxynucleotide in vivo	23	5
2454	4	4289 1981 BIOCHEMICAL PHARMACOLOGY 30(9):993-999 DESMOND PV; JAMES R; SCHENKER S; GERKENS JF; BRANCH RA PRESERVATION OF GLUCURONIDATION IN CARBON TETRACHLORIDE-INDUCED ACUTE LIVER-INJURY IN THE RAT	32	3
2455	19	10030 1996 BIOCHEMICAL PHARMACOLOGY 52(8):1311-1319 Desrochers M; Christou M; Jefcoate C; Belzil A; Anderson A New proteins in the rat CYP2B subfamily: Presence in liver microsomes of the constitutive CYP2B3 protein and the phenobarbital-inducible protein product of alternatively spliced CYP2B2 mRNA	8	1
2456	1	1365 1970 JOURNAL OF GENERAL MICROBIOLOGY 64(NOV):71-& DESSERS A; CHIANG C; LAUDELOU.H CALORIMETRIC DETERMINATION OF FREE ENERGY EFFICIENCY IN NITROBACTER-WINOGRADSKYI	10	0
2457	2	6354 1989 ANALYTICAL BIOCHEMISTRY 183(1):94-107 DETERDING LJ; SRINIVAS P; MAHMOOD NA; BURKA LT; TOMER KB FAST ATOM BOMBARDMENT AND TANDEM MASS-SPECTROMETRY FOR STRUCTURE DETERMINATION OF CYSTEINE, N-ACETYLCYSTEINE, AND GLUTATHIONE ADDUCTS OF XENOBIOTICS	37	0
2458	2	6248 1988 JOURNAL OF CLINICAL INVESTIGATION 81(3):700-709 DETURCO EBR; SPITZER JA METABOLIC-FATE OF ARACHIDONIC-ACID IN HEPATOCYTES OF CONTINUOUSLY ENDOTOXEMIC RATS	12	0
2459	2	1031 1969 BIOCHIMICA ET BIOPHYSICA ACTA 177(1):161-& DETWILER TC LEVELS OF INTERMEDIATES AND COFACTORS OF GLYCOLYTIC PATHWAY AND CITRIC ACID CYCLE IN RAT PLATELETS	15	1
2460	3	1533 1971 BIOCHIMICA ET BIOPHYSICA ACTA 244(2):303-& DETWILER TC EFFECTS OF DEOXYGLUCOSE ON PLATELET METABOLISM	24	1
2461	2	744 1968 ANALYTICAL CHEMISTRY 40(5):R19-& DEUSTACH.AJ BIOCHEMICAL ANALYSIS	4	0
2462	8	6795 1989 XENOBIOTICA 19(12):1421-1435 DEUTSCH J; VATSIS KP; LEUTZ JC; COON MJ; GELBOIN HV STUDIES ON COVALENT BINDING OF (-)TRANS-7,8-DIHYDROXY-7,8- DIHYDROBENZO[A]PYRENE METABOLITES TO CYTOCHROMES P-450 LM2 AND LM4 AND NADPH-CYTOCHROME P-450 REDUCTASE	1	0
2463	13	8886 1994 AMERICAN JOURNAL OF MEDICINE 97():S13-S23 DEVANE CL PHARMACOKINETICS OF THE NEWER ANTIDEPRESSANTS - CLINICAL RELEVANCE	54	6
2464	19	9225 1994 JOURNAL OF CLINICAL PSYCHIATRY 55(12):38-45 DEVANE CL PHARMACOGENETICS AND DRUG-METABOLISM OF NEWER ANTIDEPRESSANT AGENTS	91	17
2465	2	913 1968 JOURNAL OF NEUROCHEMISTRY 15(10):1057-& DEVELLIS J GLYCOLYSIS IN RAT BRAIN TISSUE SLICES FOLLOWING NEONATAL HEAD X-IRRADIATION - RELATION OF REGIONAL DIFFERENCES TO LDH-GPDH RATIO	2	1
2466	3	914 1968 JOURNAL OF NEUROCHEMISTRY 15(10):1061-& DEVELLIS J; INGLISH D HORMONAL CONTROL OF GLYCEROLPHOSPHATE DEHYDROGENASE IN RAT BRAIN	106	3
2467	5	6742 1989 PHARMACOLOGY & THERAPEUTICS 41(1-2):243-256 DEVEREUX TR; DOMIN BA; PHILPOT RM XENOBIOTIC METABOLISM BY ISOLATED PULMONARY CELLS	76	14
2468	3	63 1959 JOURNAL OF BIOLOGICAL CHEMISTRY 234(4):962-966 DEVLIN TM RESPIRATORY CHAIN IN PHOSPHORYLATING SUBFRAGMENTS OF MITOCHONDRIA PREPARED WITH DIGITONIN	22	8
2469	4	109 1960 JOURNAL OF BIOLOGICAL CHEMISTRY 235(7):2134-2139 DEVLIN TM; BEDELL BH EFFECT OF ACETOACETATE ON THE OXIDATION OF REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE BY INTACT RAT LIVER MITOCHONDRIA	67	21
2470	2	1753 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 152(2):521-& DEVLIN TM; CHIH JJ BIOGENESIS OF MAMMALIAN MITOCHONDRIA IN RENOPRIVAL KIDNEY .1. AMINO-ACID INCORPORATION AND RESPIRATORY ACTIVITY	16	0
2471	2	7756 1991 PHYSIOLOGIA PLANTARUM 82(4):523-528 DEVOS CHR; SCHAT H; DEWAAL MAM; VOOIJS R; ERNST WHO INCREASED RESISTANCE TO COPPER-INDUCED DAMAGE OF THE ROOT CELL PLASMALEMMA IN COPPER TOLERANT SILENE-CUCUBALUS	73	1
2472	1	6678 1989 JOURNAL OF PLANT PHYSIOLOGY 135(2):164-169 DEVOS CHR; SCHAT H; VOOIJS R; ERNST WHO COPPER-INDUCED DAMAGE TO THE PERMEABILITY BARRIER IN ROOTS OF SILENE-CUCUBALUS	59	1
2473	11	10808 1997 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 119(24):5489-5498 DeVoss JJ; Sibbesen O; Zhang ZP; deMontellano PRO Substrate docking algorithms and prediction of the substrate specificity of cytochrome P450(cam) and its L244A mutant	29	7
2474	3	10341 1996 MOLECULAR GENETICS AND EVOLUTION OF PESTICIDE RESISTANCE 645():62-71 DeWaard MA Molecular genetics of resistance in fungi to azole fungicides	13	2
2475	3	792 1968 BIOCHEMICAL PHARMACOLOGY 17(9):1901-& DEWAIDE JH; HENDERSO.PT HEPATIC N-DEMETHYLATION OF AMINOPYRINE IN RAT AND TROUT	52	7
2476	6	7181 1990 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 253(1):387-394 DEWAZIERS I; CUGNENC PH; YANG CS; LEROUX JP; BEAUNE PH CYTOCHROME-P-450 ISOENZYMES, EPOXIDE HYDROLASE AND GLUTATHIONE TRANSFERASES IN RAT AND HUMAN HEPATIC AND EXTRAHEPATIC TISSUES	270	86
2477	18	11518 1999 BIOCHEMICAL PHARMACOLOGY 58(3):525-537 Dey A; Jones JE; Nebert DW Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hybridization	32	7
2478	4	11017 1998 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 251(2):657-661 Dey A; Nebert DW Markedly increased constitutive CYP1A1 mRNA levels in the fertilized ovum of the mouse	18	6
2479	9	6752 1989 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 86(19):7446-7450 DEY A; WESTPHAL H; NEBERT DW CELL-SPECIFIC INDUCTION OF MOUSE CYP1A1 MESSENGER-RNA DURING DEVELOPMENT	32	15
2480	2	3655 1978 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 9(11):1099-1104 DEY AC; SENCIALL IR ACIDIC STEROID METABOLITES - BIOSYNTHESIS OF STEROID CARBOXYLIC-ACIDS BY RABBIT LIVER-MICROSOMES AND INVOLVEMENT OF A CYTOCHROME P-450-INDEPENDENT MIXED-FUNCTION OXIDASE SYSTEM	5	2
2481	17	2860 1975 JOURNAL OF CHROMATOGRAPHY ():1-861 DEYL Z; KOPECKY J; DAVIDEK J; JURICOVA M; HELM R BIBLIOGRAPHY OF ELECTROPHORESIS 1968-1972 AND SURVEY OF APPLICATIONS (SUPPLEMENTARY VOLUME NO 4, 1975 TO JOURNAL OF CHROMATOGRAPHY) - INTRODUCTION	0	0
2482	1	1552 1971 CANADIAN JOURNAL OF BIOCHEMISTRY 49(11):1202-& DHALLA NS; FEDELESO.M; TOFFLER I BIOCHEMICAL ALTERATIONS IN SKELETAL MUSCLE OF VITAMIN-E DEFICIENT RATS	28	1
2483	3	2163 1973 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 51(8):590-603 DHALLA NS; MATOUSHE.RF; SUN CN; OLSON RE METABOLIC, ULTRASTRUCTURAL, AND MECHANICAL CHANGES IN ISOLATED RAT-HEART PERFUSED WITH AEROBIC MEDIUM IN ABSENCE OR PRESENCE OF GLUCOSE	27	0
2484	2	4741 1983 ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 161():305-316 DHALLA NS; SINGH JN; MCNAMARA DB; BERNATSKY A; SINGH A; HARROW JAC ENERGY-PRODUCTION AND UTILIZATION IN CONTRACTILE FAILURE DUE TO INTRACELLULAR CALCIUM OVERLOAD	2	0
2485	2	1848 1972 CANADIAN JOURNAL OF BIOCHEMISTRY 50(5):550-& DHALLA NS; TOFFLER I; FEDELESO.M ENERGY METABOLISM OF SKELETAL-MUSCLE OF GENETICALLY DYSTROPHIC HAMSTER	30	0
2486	1	1851 1972 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 50(4):333-& DHALLA NS; WALZ DA; YATES JC; MCDONALD VA; OLSON RE CORRELATION BETWEEN CHANGES IN ENDOGENOUS ENERGY STORES AND MYOCARDIAL FUNCTION DUE TO HYPOXIA IN ISOLATED PERFUSED RAT- HEART	91	2
2487	17	7438 1991 BIOCHEMISTRY 30(20):4940-4949 DHARIWAL MS; KOWLURU RA; JEFCOATE CR CYTOCHROME P-450SCC INDUCES VESICLE AGGREGATION THROUGH A SECONDARY INTERACTION AT THE ADRENODOXIN BINDING-SITES (IN COMPETITION WITH PROTEIN EXCHANGE)	9	1
2488	4	9041 1994 CARCINOGENESIS 15(9):1923-1930 DHAUNSI GS; SINGH I; ORAK JK; SINGH AK ANTIOXIDANT ENZYMES IN CIPROFIBRATE-INDUCED OXIDATIVE STRESS	16	1
2489	9	11786 1999 MOLECULAR AND CELLULAR BIOCHEMISTRY 200(1-2):169-176 Dhawan A; Parmar D; Dayal M; Seth PK Cytochrome P450 (P450) isoenzyme specific dealkylation of alkoxyresorufins in rat brain microsomes	7	0
2490	4	10771 1997 JOURNAL OF ETHNOPHARMACOLOGY 56(2):159-164 Dhuley JN; Naik SR Protective effect of Rhinax, a herbal formulation, against CCl4-induced liver injury and survival in rats	1	0
2491	1	11352 1998 ONCOLOGY RESEARCH 10(10):491-498 Di Padova M; Barbieri R; Fanciulli M; Arcuri E; Floridi A Effect of local anesthetic ropivacaine on the energy metabolism of Ehrlich ascites tumor cells	1	0
2492	14	11557 1999 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 77(8):589-597 Di Re J; Lee C; Riddick DS Lack of mechanism-based inactivation of rat hepatic microsomal cytochromes P450 by doxorubicin	2	0
2493	18	9081 1994 DRUG METABOLISM AND DISPOSITION 22(1):65-73 DIAMOND S; RAKESTRAW D; ONEIL J; LAM GN; CHRIST DD INDUCTION OF CYTOCHROMES P-450 2B AND 3A IN MICE FOLLOWING THE DIETARY ADMINISTRATION OF THE NOVEL COGNITIVE ENHANCER LINOPIRDINE	5	1
2494	8	1002 1969 BIOCHEMICAL JOURNAL 115(3):547-& DIAUGUST.RP; FOUTS JR EFFECTS OF UNSATURATED FATTY ACIDS ON HEPATIC MICROSOMAL DRUG METABOLISM AND CYTOCHROME P-450	53	0
2495	11	9363 1994 TOXICOLOGY 86(1-2):109-122 DIAZ MJ; CHINJE E; KENTISH P; JARNOT B; GEORGE M; GIBSON G INDUCTION OF CYTOCHROME P4504A BY THE PEROXISOME PROLIFERATOR PERFLUORO-N-OCTANOIC ACID	6	4
2496	7	8477 1993 BIOCHEMICAL PHARMACOLOGY 46(6):1076-1080 DIAZ MJ; CHINJE E; KENTISH P; JARNOT B; GEORGE M; GIBSON GG CHLOROTRIFLUOROETHYLENE TRIMER AND TETRAMER ARE INDUCERS OF THE CYP4A SUBFAMILY	4	2
2497	6	2364 1973 TOXICOLOGY AND APPLIED PHARMACOLOGY 25(4):534-541 DIAZGOME.MI; CASTRO JA; DEFERREY.EC; DACOSTA N; DECASTRO CR IRREVERSIBLE BINDING OF C-14 FROM C-14/CL4 TO LIVER MICROSOMAL LIPIDS AND PROTEINS FROM RATS PRETREATED WITH COMPOUNDS ALTERING MICROSOMAL MIXED-FUNCTION OXYGENASE ACTIVITY	41	0
2498	7	2911 1975 TOXICOLOGY AND APPLIED PHARMACOLOGY 34(1):102-114 DIAZGOMEZ MI; CASTRO CRD; DACOSTA N; FENOS OMD; FERREYRA ECD; CASTRO JA SPECIES-DIFFERENCES IN CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY - ROLE OF CCL4 ACTIVATION AND OF LIPID PEROXIDATION	41	7
2499	8	3355 1977 EXPERIENTIA 33(5):643-645 DIAZGOMEZ MI; CASTRO JA SPECTRAL CHANGES RESULTING FROM INTERACTION OF SOME N-ALKYL NITROSAMINES AND RAT-LIVER MICROSOMES	4	0
2500	4	2907 1975 TOXICOLOGY AND APPLIED PHARMACOLOGY 32(1):101-108 DIAZGOMEZ MI; DECASTRO CR; DEFERREYRA EC; DACOSTA N; DEFENOS OM; CASTRO JA MECHANISTIC STUDIES ON CARBON-TETRACHLORIDE HEPATOTOXICITY IN FASTED AND FED RATS	9	0

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