#	Cited nodes	Nodes / Authors	GCS	LCS
6601	13	12535 2001 JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY 76(3):237-244 Lewis DFV COMPACT: a structural approach to the modelling of cytochromes P450 and their interactions with xenobiotics	7	0
6602	30	12868 2002 JOURNAL OF INORGANIC BIOCHEMISTRY 91(4):502-514 Lewis DFV Modelling human cytochromes P450 involved in drug metabolism from the CYP2C5 crystallographic template	2	0
6603	26	12266 2000 XENOBIOTICA 30(1):1-25 Lewis DFV; Bird MG; Dickins M; Lake BG; Eddershaw PJ; Tarbit MH; Goldfarb PS Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the putative active site of the human CYP2E1 isoform	15	4
6604	13	10904 1997 TOXICOLOGY 118(2-3):93-113 Lewis DFV; Bird MG; Parke DV Molecular modelling of CYP2E1 enzymes from rat, mouse and man: An explanation for species differences in butadiene metabolism and potential carcinogenicity, and rationalization of CYP2E substrate specificity	21	11
6605	27	11858 1999 TOXICOLOGY 133(1):1-33 Lewis DFV; Dickens M; Lake BG; Eddershaw PJ; Tarbit MH; Goldfarb PS Molecular modelling of the human cytochrome P450 isoform CYP2A6 and investigations of CYP2A substrate selectivity	15	5
6606	27	11426 1998 XENOBIOTICA 28(3):235-268 Lewis DFV; Dickins M; Weaver RJ; Eddershaw PJ; Goldfarb PS; Tarbit MH Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site- directed mutagenesis experiments in the CYP2C subfamily	29	8
6607	19	11116 1998 CHEMICO-BIOLOGICAL INTERACTIONS 115(3):175-199 Lewis DFV; Eddershaw PJ; Dickens M; Tarbit MH; Goldfarb PS Structural determinants of cytochrome P450 substrate specificity, binding affinity and catalytic rate	20	7
6608	25	10450 1996 XENOBIOTICA 26(10):1067-1086 Lewis DFV; Eddershaw PJ; Goldfarb PS; Tarbit MH Molecular modelling of CYP3A4 from an alignment with CYP102: Identification of key interactions between putative active site residues and CYP3A-specific chemicals	49	29
6609	19	10926 1997 XENOBIOTICA 27(4):319-339 Lewis DFV; Eddershaw PJ; Goldfarb PS; Tarbit MH Molecular modelling of cytochrome P4502D6 (CYP2D6) based on an alignment with CYP102: Structural studies on specific CYP2D6 substrate metabolism	49	16
6610	50	11970 2000 BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1460(2-3):353-374 Lewis DFV; Hlavica P Interactions between redox partners in various cytochrome P450 systems: functional and structural aspects	8	3
6611	10	6529 1989 CHEMICO-BIOLOGICAL INTERACTIONS 70(3-4):263-280 LEWIS DFV; IOANNIDES C; PARKE DV MOLECULAR-ORBITAL STUDIES OF OXYGEN ACTIVATION AND MECHANISMS OF CYTOCHROMES-P-450-MEDIATED OXIDATIVE-METABOLISM OF XENOBIOTICS	25	8
6612	5	9496 1995 BIOCHEMICAL PHARMACOLOGY 50(5):619-625 LEWIS DFV; IOANNIDES C; PARKE DV A QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP STUDY ON A SERIES OF 10 PARASUBSTITUTED TOLUENES BINDING TO CYTOCHROME P4502B4 (CYP2B4), AND THEIR HYDROXYLATION RATES	17	9
6613	11	11194 1998 ENVIRONMENTAL HEALTH PERSPECTIVES 106(10):633-641 Lewis DFV; Ioannides C; Parke DV Cytochromes P450 and species differences in xenobiotic metabolism and activation of carcinogen	23	3
6614	3	8875 1993 XENOBIOTICA 23(1):79-96 LEWIS DFV; LAKE BG INTERACTION OF SOME PEROXISOME PROLIFERATORS WITH THE MOUSE- LIVER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR) - A MOLECULAR MODELING AND QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP (QSAR) STUDY	28	5
6615	12	9903 1995 XENOBIOTICA 25(6):585-598 LEWIS DFV; LAKE BG MOLECULAR MODELING OF MEMBERS OF THE P4502A SUBFAMILY - APPLICATION TO STUDIES OF ENZYME SPECIFICITY	39	24
6616	42	10444 1996 XENOBIOTICA 26(7):723-753 Lewis DFV; Lake BG Molecular modelling of CYP1A subfamily members based on an alignment with CYP102: Rationalization of CYP1A substrate specificity in terms of active site amino acid residues	45	22
6617	48	10930 1997 XENOBIOTICA 27(5):443-478 Lewis DFV; Lake BG Molecular modelling of mammalian CYP2B isoforms and their interaction with substrates, inhibitors and redox partners	33	13
6618	26	11882 1999 XENOBIOTICA 29(8):763-781 Lewis DFV; Lake BG Molecular modelling of CYP4A subfamily members based on sequence homology with CYP102	9	5
6619	54	11877 1999 XENOBIOTICA 29(4):361-393 Lewis DFV; Lake BG; Dickins M; Eddershaw PJ; Tarbit MH; Goldfarb PS Molecular modelling of CYP2B6, the human CYP2B isoform, by homology with the substrate-bound CYP102 crystal structure: evaluation of CYP2B6 substrate characteristics, the cytochrome b(5) binding site and comparisons with CYP2B1 and CYP2B4	26	10
6620	38	11859 1999 TOXICOLOGY 139(1-2):53-79 Lewis DFV; Lake BG; George SG; Dickins M; Eddershaw PJ; Tarbit MH; Beresford AP; Goldfarb PS; Guengerich FP Molecular modelling of CYP1 family enzymes CYP1A1, CYP1A2, CYP1A6 and CYP1B1 based on sequence homology with CYP102	16	5
6621	25	11311 1998 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 66(4):217-233 Lewis DFV; Lee-Robichaud P Molecular modelling of steroidogenic cytochromes P450 from families CYP11, CYP17, CYP19 and CYP21 based on the CYP102 crystal structure	13	3
6622	15	12786 2002 DRUG METABOLISM REVIEWS 34(1-2):69-82 Lewis DFV; Modi S; Dickins M Structure-activity relationship for human cytochrome P450 substrates and inhibitors	5	0
6623	25	8201 1992 JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN 6(3):235-252 LEWIS DFV; MOEREELS H THE SEQUENCE HOMOLOGIES OF CYTOCHROMES-P-450 AND ACTIVE-SITE GEOMETRIES	43	22
6624	29	11185 1998 DRUG METABOLISM REVIEWS 30(4):739-786 Lewis DFV; Pratt JM The P450 catalytic cycle and oxygenation mechanism	22	9
6625	11	5615 1986 CHEMICO-BIOLOGICAL INTERACTIONS 58(3):289-299 LEWIS DFV; TAMBURINI PP; GIBSON GG THE INTERACTION OF A HOMOLOGOUS SERIES OF HYDROCARBONS WITH HEPATIC CYTOCHROME-P-450 - MOLECULAR ORBITAL-DERIVED ELECTRONIC AND STRUCTURAL PARAMETERS INFLUENCING THE HEMOPROTEIN SPIN STATE	16	5
6626	36	11339 1998 MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH 410(3):245-270 Lewis DFV; Watson E; Lake BG Evolution of the cytochrome P450 superfamily: sequence alignments and pharmacogenetics	25	14
6627	13	11737 1999 JOURNAL OF ENZYME INHIBITION 14(3):175-+ Lewis DFV; Wiseman A; Tarbit MH Molecular modelling of lanosterol 14 alpha-demethylase (CYP51) from Saccharomyces cerevisiae via homology with CYP102, a unique bacterial cytochrome P450 isoform: Quantitative structure-activity relationships (QSARs) within two related series of antifungal azole derivatives	9	1
6628	3	2865 1975 JOURNAL OF NEUROPHYSIOLOGY 38(2):405-417 LEWIS DV; SCHUETTE WH NADH FLUORESCENCE AND [K+]0 CHANGES DURING HIPPOCAMPAL ELECTRICAL-STIMULATION	107	0
6629	3	715 1967 NATURE 215(5108):1408-& LEWIS SE EFFECT OF CARBON MONOXIDE ON METABOLISM OF INSECTICIDES IN VIVO	7	3
6630	1	7601 1991 JOURNAL OF APPLIED PHYSIOLOGY 70(1):391-398 LEWIS SF; VORA S; HALLER RG ABNORMAL OXIDATIVE-METABOLISM AND O2 TRANSPORT IN MUSCLE PHOSPHOFRUCTOKINASE DEFICIENCY	17	4
6631	15	13069 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(7):5141-5147 Leys D; Mowat CG; McLean KJ; Richmond A; Chapman SK; Walkinshaw MD; Munro AW Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450	2	1
6632	6	10082 1996 BRITISH JOURNAL OF PHARMACOLOGY 118(1):57-62 Li CG; Rand MJ Inhibition of NO-mediated responses by 7-ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P-450	11	1
6633	4	6776 1989 TOXICOLOGY LETTERS 45(2-3):141-147 LI D; BRADY JF; LEE MJ; YANG CS EFFECT OF 1,3-BUTANEDIOL ON RAT-LIVER MICROSOMAL NDMA DEMETHYLATION AND OTHER MONOOXYGENASE ACTIVITIES	0	0
6634	18	11755 1999 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 289(2):661-667 Li DN; Pritchard MP; Hanlon SP; Burchell B; Wolf CR; Friedberg T Competition between cytochrome P-450 isozymes for NADPH- cytochrome P-450 oxidoreductase affects drug metabolism	8	2
6635	16	10339 1996 MOLECULAR AND CELLULAR ENDOCRINOLOGY 120(1):77-83 Li H; Liu SQ; Kemper B Sex- and tissue-specific expression of a cytochrome P450 2C2- luciferase transgene	3	1
6636	14	9713 1995 JOURNAL OF BIOCHEMICAL TOXICOLOGY 10(1):51-61 LI HC; DEHAL SS; KUPFER D INDUCTION OF THE HEPATIC CYP2B AND CYP3A ENZYMES BY THE PROESTROGENIC PESTICIDE METHOXYCHLOR AND BY DDT IN THE RAT - EFFECTS ON METHOXYCHLOR METABOLISM	16	1
6637	13	13051 2003 ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 22(3):636-644 Li HX; Boon JP; Lewis WE; van den Berg M; Nyman M; Letcher RJ Hepatic microsomal cytochrome P450 enzyme activity in relation to in vitro metabolism/inhibition of polychlorinated biphenyls and testosterone in Baltic grey seal (Halichoerus grypus)	0	0
6638	4	13050 2003 ENVIRONMENTAL SCIENCE & TECHNOLOGY 37(5):832-839 Li HX; Drouillard KG; Bennett E; Haffner GD; Letcher RJ Plasma-associated halogenated phenolic contaminants in benthic and pelagic fish species from the Detroit River	1	0
6639	14	12861 2002 JOURNAL OF CHROMATOGRAPHIC SCIENCE 40(7):397-402 Li HX; Letcher RJ A high-performance-liquid-chromatography-based method for the determination of hydroxylated testosterone metabolites formed in vitro in liver microsomes from gray seal (Halichoerus grypus)	1	1
6640	4	7629 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(18):11909-11914 LI HY; DARWISH K; POULOS TL CHARACTERIZATION OF RECOMBINANT BACILLUS-MEGATERIUM CYTOCHROME- P-450BM-3 AND ITS 2 FUNCTIONAL DOMAINS	62	46
6641	16	11534 1999 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1441(2-3):141-149 Li HY; Poulos TL Fatty acid metabolism, conformational change, and electron transfer in cytochrome P-450(BM-3)	10	6
6642	15	12310 2001 APPLIED AND ENVIRONMENTAL MICROBIOLOGY 67(12):5735-5739 Li QS; Ogawa J; Schmid RD; Shimizu S Engineering cytochrome P450BM-3 for oxidation of polycyclic aromatic hydrocarbons	4	3
6643	12	12344 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 280(5):1258-1261 Li QS; Ogawa J; Shimizu S Critical role of the residue size at position 87 in H2O2- dependent substrate hydroxylation activity and H2O2 inactivation of cytochrome P450BM-3	6	4
6644	7	12376 2001 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1545(1-2):114-121 Li QS; Schwaneberg U; Fischer M; Schmitt J; Pleiss J; Lutz-Wahl S; Schmid RD Rational evolution of a medium chain-specific cytochrome P-450 BM-3 variant	14	5
6645	9	12002 2000 CHEMISTRY-A EUROPEAN JOURNAL 6(9):1531-1536 Li QS; Schwaneberg U; Fischer P; Schmid RD Directed evolution of the fatty-acid hydyoxylase P450BM-3 into an indole-hydroxylating catalyst	19	8
6646	3	1742 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 150(2):397-& LI T; HARRIS BG; GRACY RW STUDIES ON ENZYMES FROM PARASITIC HELMINTHS .2. PURIFICATION AND PROPERTIES OF MALIC ENZYME FROM TAPEWORM HYMENOLEPIS- DIMINUTA	30	3
6647	16	11036 1998 BIOCHEMICAL PHARMACOLOGY 56(5):599-612 Li W; Harper PA; Tang BK; Okey AB Regulation of cytochrome p450 enzymes by aryl hydrocarbon receptor in human cells - CYP1A2 expression in the LS180 colon carcinoma cell line after treatment with 2,3,7,8- tetrachlorodibenzo-p-dioxin or 3-methylcholanthrene	25	2
6648	7	12833 2002 INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 32(3):311-320 Li XC; Berenbaum MR; Schuler MA Cytochrome P450 and actin genes expressed in Helicoverpa zea and Helicoverpa armigera: paralogy/orthology identification, gene conversion and evolution	4	0
6649	12	12678 2002 ANALYTICA CHIMICA ACTA 457(2):165-171 Li XF; Ma MS; Cheng A; Zheng J; Tam YK Determination of testosterone and its metabolites using liquid chromatography with elevated column temperature and flow-rate gradient	0	0
6650	11	7636 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(29):19186-19191 LI YC; CHIANG JYL THE EXPRESSION OF A CATALYTICALLY ACTIVE CHOLESTEROL 7-ALPHA- HYDROXYLASE CYTOCHROME-P450 IN ESCHERICHIA-COLI	56	41
6651	5	7142 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(20):12012-12019 LI YC; WANG DP; CHIANG JYL REGULATION OF CHOLESTEROL 7-ALPHA-HYDROXYLASE IN THE LIVER - CLONING, SEQUENCING, AND REGULATION OF CHOLESTEROL 7-ALPHA- HYDROXYLASE MESSENGER-RNA	149	24
6652	5	8526 1993 BIOLOGY OF REPRODUCTION 49(6):1293-1302 LI Z; JOHNSON AL EXPRESSION AND REGULATION OF CYTOCHROME-P450 17-ALPHA- HYDROXYLASE MESSENGER-RIBONUCLEIC-ACID LEVELS AND ANDROSTENEDIONE PRODUCTION IN HEN GRANULOSA-CELLS	21	0
6653	8	12119 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(22):16543-16549 Li-Hawkins J; Lund EG; Bronson AD; Russell DW Expression cloning of an oxysterol 7 alpha-hydroxylase selective for 24-hydroxycholesterol	25	0
6654	19	12283 2000 YEAST 16(12):1077-1087 Lida T; Sumita T; Ohta A; Takagi M The cytochrome P450ALK multigene family of an n-alkane- assimilating yeast, Yarrowia lipolytica: cloning and characterization of genes coding for new CYP52 family members	4	1
6655	1	5840 1987 CANCER DRUG DELIVERY 4(3):159-167 LIDDIL JD; DORR RT SCHEDULE-DEPENDENT TOXICITY OF TUMOR NECROSIS FACTOR IN RODENTS	3	0
6656	21	12946 2002 SEMINARS IN LIVER DISEASE 22(2):115-122 Liddle C; Goodwin B Regulation of hepatic drug metabolism: Role of the nuclear receptors PXR and CAR	5	0
6657	6	6603 1989 GASTROENTEROLOGY 96(3):864-872 LIDDLE C; MURRAY M; FARRELL GC EFFECT OF LIVER-REGENERATION ON HEPATIC CYTOCHROME-P450 ISOZYMES AND SERUM SEX STEROIDS IN THE MALE-RAT	33	4
6658	3	518 1966 GASTROENTEROLOGY 50(1):119-& LIEBER CS HEPATIC AND METABOLIC EFFECTS OF ALCOHOL	89	4
6659	4	582 1967 ANNUAL REVIEW OF MEDICINE 18():35-& LIEBER CS METABOLIC DERANGEMENT INDUCED BY ALCOHOL	106	7
6660	5	671 1967 FEDERATION PROCEEDINGS 26(5):1443-& LIEBER CS CHRONIC ALCOHOLIC HEPATIC INJURY IN EXPERIMENTAL ANIMALS AND MAN - BIOCHEMICAL PATHWAYS AND NUTRITIONAL FACTORS	56	4
6661	17	2246 1973 GASTROENTEROLOGY 65(5):821-846 LIEBER CS HEPATIC AND METABOLIC EFFECTS OF ALCOHOL (1966 TO 1973)	132	4
6662	15	2659 1975 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 252(APR25):24-50 LIEBER CS INTERFERENCE OF ETHANOL IN HEPATIC CELLULAR-METABOLISM	53	3
6663	10	3983 1980 AMERICAN JOURNAL OF GASTROENTEROLOGY 74(4):313-320 LIEBER CS INTERACTION OF ETHANOL WITH DRUG TOXICITY	19	2
6664	18	4747 1983 ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY 92(4):267-311 LIEBER CS ETHANOL-METABOLISM AND TOXICITY	0	0
6665	16	4979 1983 PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR 18():181-187 LIEBER CS MICROSOMAL ETHANOL OXIDIZING SYSTEM (MEOS) - INTERACTION WITH ETHANOL, DRUGS AND CARCINOGENS	14	0
6666	18	4991 1983 REVIEWS IN BIOCHEMICAL TOXICOLOGY (5):267-311 LIEBER CS ETHANOL-METABOLISM AND TOXICITY	1	0
6667	7	6102 1988 BIOCHEMICAL SOCIETY TRANSACTIONS 16(3):232-239 LIEBER CS THE MICROSOMAL ETHANOL OXIDIZING SYSTEM - ITS ROLE IN ETHANOL AND XENOBIOTIC METABOLISM	23	4
6668	9	6275 1988 MOLECULAR ASPECTS OF MEDICINE 10(2):107-146 LIEBER CS PATHO-PHYSIOLOGY OF ALCOHOLIC LIVER-DISEASE	12	0
6669	8	6290 1988 NEW ENGLAND JOURNAL OF MEDICINE 319(25):1639-1650 LIEBER CS BIOCHEMICAL AND MOLECULAR-BASIS OF ALCOHOL-INDUCED INJURY TO LIVER AND OTHER TISSUES	302	21
6670	7	6316 1988 SEMINARS IN LIVER DISEASE 8(1):47-68 LIEBER CS METABOLIC EFFECTS OF ETHANOL AND ITS INTERACTION WITH OTHER DRUGS, HEPATOTOXIC AGENTS, VITAMINS, AND CARCINOGENS - A 1988 UPDATE	52	6
6671	14	6802 1990 ALCOHOL AND ALCOHOLISM 25(2-3):157-176 LIEBER CS INTERACTION OF ETHANOL WITH DRUGS, HEPATOTOXIC AGENTS, CARCINOGENS AND VITAMINS	41	4
6672	9	7038 1990 DRUGS 40():23-44 LIEBER CS INTERACTION OF ALCOHOL WITH OTHER DRUGS AND NUTRIENTS - IMPLICATION FOR THE THERAPY OF ALCOHOLIC LIVER-DISEASE	28	0
6673	10	7263 1990 PHARMACOLOGY & THERAPEUTICS 46(1):1-41 LIEBER CS MECHANISM OF ETHANOL INDUCED HEPATIC-INJURY	114	10
6674	11	7341 1991 ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 15(4):573-592 LIEBER CS HEPATIC, METABOLIC AND TOXIC EFFECTS OF ETHANOL - 1991 UPDATE	139	7
6675	15	7691 1991 JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION 10(6):602-632 LIEBER CS ALCOHOL, LIVER, AND NUTRITION	63	0
6676	17	9273 1994 JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY 32(6):631-681 LIEBER CS MECHANISMS OF ETHANOL-DRUG-NUTRITION INTERACTIONS	44	3
6677	15	10623 1997 CLINICA CHIMICA ACTA 257(1):59-84 Lieber CS Ethanol metabolism, cirrhosis and alcoholism	60	2
6678	84	10867 1997 PHYSIOLOGICAL REVIEWS 77(2):517-544 Lieber CS Cytochrome P-4502E1: Its physiological and pathological role	181	22
6679	48	11446 1999 ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 23(6):991-1007 Lieber CS Microsomal ethanol-oxidizing system (MEOS): The first 30 years (1968-1998) - A review	60	4
6680	17	12295 2001 AMERICAN JOURNAL ON ADDICTIONS 10():29-50 Lieber CS Liver diseases by alcohol and hepatitis C: Early detection and new insights in pathogenesis lead to improved treatment	6	0
6681	2	150 1962 AMERICAN JOURNAL OF MEDICINE 33(3):319-& LIEBER CS; DAVIDSON CS SOME METABOLIC EFFECTS OF ETHYL ALCOHOL	184	13
6682	6	1349 1970 JOURNAL OF BIOLOGICAL CHEMISTRY 245(10):2505-& LIEBER CS; DECARLI LM HEPATIC MICROSOMAL ETHANOL-OXIDIZING SYSTEM - IN-VITRO CHARACTERISTICS AND ADAPTIVE PROPERTIES IN-VIVO	681	92
6683	7	1210 1970 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 40(4):858-& LIEBER CS; RUBIN E; DECARLI LM HEPATIC MICROSOMAL ETHANOL OXIDIZING SYSTEM (MEOS) - DIFFERENTIATION FROM ALCOHOL DEHYDROGENASE AND NADPH OXIDASE	51	10
6684	16	2819 1975 FEDERATION PROCEEDINGS 34(11):2060-2074 LIEBER CS; TESCHKE R; HASUMURA Y; DECARLI LM DIFFERENCES IN HEPATIC AND METABOLIC CHANGES AFTER ACUTE AND CHRONIC ALCOHOL CONSUMPTION	72	2
6685	30	358 1965 ANNUAL REVIEW OF PLANT PHYSIOLOGY 16():343-& LIEBERMA.M; BAKER JE RESPIRATORY ELECTRON TRANSPORT	41	0
6686	5	10212 1996 GYNECOLOGIC AND OBSTETRIC INVESTIGATION 41(3):147-172 Lieberman S Are estradiol-producing cells incompletely endowed? A chronicle of the emergence of certitude from conjecture	3	1
6687	2	5841 1987 CANCER RESEARCH 47(8):2156-2159 LIEHR JG; HALL ER; AVITTS TA; RANDERATH E; RANDERATH K LOCALIZATION OF ESTROGEN-INDUCED DNA ADDUCTS AND CYTOCHROME-P- 450 ACTIVITY AT THE SITE OF RENAL CARCINOGENESIS IN THE HAMSTER-KIDNEY	34	2
6688	5	7193 1990 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 35(5):555-560 LIEHR JG; ROY D; ARIULUBELEN A; BUI QD; WEISZ J; STROBEL HW EFFECT OF CHRONIC ESTROGEN-TREATMENT OF SYRIAN-HAMSTERS ON MICROSOMAL-ENZYMES MEDIATING FORMATION OF CATECHOLESTROGENS AND THEIR REDOX CYCLING - IMPLICATIONS FOR CARCINOGENESIS	29	5
6689	18	4141 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(9):4264-4277 LIGHT DR; WALSH C FLAVIN ANALOGS AS MECHANISTIC PROBES OF ADRENODOXIN REDUCTASE- DEPENDENT ELECTRON-TRANSFER TO THE CHOLESTEROL SIDE-CHAIN CLEAVAGE CYTOCHROME-P-450 OF THE ADRENAL-CORTEX	49	6
6690	15	1914 1972 JOURNAL OF APPLIED CHEMISTRY AND BIOTECHNOLOGY 22(4):509-& LIGHT PA INFLUENCE OF ENVIRONMENT ON MITOCHONDRIAL FUNCTION IN YEAST	17	0
6691	16	1480 1971 BIOCHEMICAL JOURNAL 124(1):123-& LIGHT PA; GARLAND PB COMPARISON OF MITOCHONDRIA FROM TORULOPSIS-UTILIS GROWN IN CONTINUOUS CULTURE WITH GLYCEROL, IRON, AMMONIUM, MAGNESIUM OR PHOSPHATE AS GROWTH-LIMITING NUTRIENT	74	6
6692	2	3268 1977 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 79(1):226-233 LILES S; RAMACHANDRAN J REGULATION OF DELTA5-3BETA-HYDROXYSTEROID DEHYDROGENASE- ISOMERASE ACTIVITY IN ADRENOCORTICAL CELL-CULTURES BY ADRENOCORTICOTROPIN	27	3
6693	10	4533 1982 BIOCHEMICAL PHARMACOLOGY 31(6):907-913 LILIENBLUM W; WALLI AK; BOCK KW DIFFERENTIAL INDUCTION OF RAT-LIVER MICROSOMAL UDP- GLUCURONOSYLTRANSFERASE ACTIVITIES BY VARIOUS INDUCING AGENTS	187	10
6694	13	8605 1993 ENDOCRINOLOGY 132(6):2498-2506 LIN D; BLACK SM; NAGAHAMA Y; MILLER WL STEROID 17-ALPHA-HYDROXYLASE AND 17,20-LYASE ACTIVITIES OF P450C17 - CONTRIBUTIONS OF SERINE(106) AND P450 REDUCTASE	76	30
6695	11	7632 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(24):15992-15998 LIN D; HARIKRISHNA JA; MOORE CCD; JONES KL; MILLER WL MISSENSE MUTATION SERINE-106 -] PROLINE CAUSES 17-ALPHA- HYDROXYLASE DEFICIENCY	81	28
6696	17	9295 1994 MOLECULAR ENDOCRINOLOGY 8(3):392-402 LIN D; ZHANG LH; CHIAO E; MILLER WL MODELING AND MUTAGENESIS OF THE ACTIVE-SITE OF HUMAN P450C17	39	17
6697	1	2349 1973 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 70(12):3450-3453 LIN DC; KUN E INHIBITION OF OXIDATION OF GLUTAMATE AND ISOCITRATE IN LIVER- MITOCHONDRIA AT A SPECIFIC NADP+-REDUCING SITE	4	0
6698	31	3239 1977 ANNUAL REVIEW OF BIOCHEMISTRY 46():765-795 LIN ECC GLYCEROL UTILIZATION AND ITS REGULATION IN MAMMALS	199	2
6699	19	13021 2003 CHEMICAL RESEARCH IN TOXICOLOGY 16(2):129-136 Lin HL; Kent UM; Zhang HM; Waskell L; Hollenberg PF Mutation of tyrosine 190 to alanine eliminates the inactivation of cytochrome P4502B1 by peroxynitrite	1	0
6700	16	11181 1998 DRUG METABOLISM AND DISPOSITION 26(12):1202-1212 Lin JH Applications and limitations of interspecies scaling and in vitro extrapolation in pharmacokinetics	25	2

#	Cited nodes	Nodes / Authors	GCS	LCS
6701	14	12027 2000 CURRENT DRUG METABOLISM 1(4):305-331 Lin JH Sense and nonsense in the prediction of drug-drug interactions	5	0
6702	20	11824 1999 PHARMACOLOGICAL REVIEWS 51(2):135-157 Lin JH; Chiba M; Baillie TA Is the role of the small intestine in first-pass metabolism overemphasized?	50	4
6703	11	10471 1997 ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 32 32():295-304 Lin JH; Lu AYH Inhibition of cytochrome P-450 and implications in drug development	9	3
6704	42	10865 1997 PHARMACOLOGICAL REVIEWS 49(4):403-449 Lin JH; Lu AYH Role of pharmacokinetics and metabolism in drug discovery and development	90	11
6705	45	11126 1998 CLINICAL PHARMACOKINETICS 35(5):361-390 Lin JH; Lu AYH Inhibition and induction of cytochrome P450 and the clinical implications	122	31
6706	23	12306 2001 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 41():535-567 Lin JH; Lu AYH Interindividual variability in inhibition and induction of cytochrome P450 enzymes	23	5
6707	16	10402 1996 PSYCHOPHARMACOLOGY BULLETIN 32(2):205-217 Lin KM; Poland RE; Wan YJY; Smith MW; Lesser IM The evolving science of pharmacogenetics: Clinical and ethnic perspectives	20	2
6708	14	2402 1974 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 164(2):429-439 LIN MT; HAKSAR A; PERON FG ROLE OF KREBS CYCLE IN GENERATION OF INTRAMITOCHONDRIAL REDUCING EQUIVALENTS FOR 1 1 BETA-HYDROXYLATION OF DEOXYCORTICOSTERONE IN ISOLATED RAT ADRENAL-CELLS	14	4
6709	10	2556 1974 JOURNAL OF BIOLOGICAL CHEMISTRY 249(12):3867-3875 LIN RC; DAVIS EJ MALIC ENZYMES OF RABBIT HEART-MITOCHONDRIA - SEPARATION AND COMPARISON OF SOME CHARACTERISTICS OF A NICOTINAMIDE ADENINE DINUCLEOTIDE-PREFERRING AND A NICOTINAMIDE ADENINE-DINUCLEOTIDE PHOSPHATE-SPECIFIC ENZYME	103	23
6710	13	11196 1998 ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 17(3):439-445 Lin S; Bullock PL; Addison RF; Bandiera SM Detection of cytochrome P4501A in several species using antibody against a synthetic peptide derived from rainbow trout cytochrome P4501A1	9	1
6711	3	5461 1985 LIFE SCIENCES 36(13):1255-1264 LIN T MECHANISM OF ACTION OF GONADOTROPIN-RELEASING HORMONE STIMULATED LEYDIG-CELL STEROIDOGENESIS .3. THE ROLE OF ARACHIDONIC-ACID AND CALCIUM PHOSPHOLIPID DEPENDENT PROTEIN- KINASE	46	1
6712	5	9293 1994 MOLECULAR AND CELLULAR ENDOCRINOLOGY 101(1-2):111-119 LIN T; WANG DL; NAGPAL ML; CHANG WW RECOMBINANT MURINE TUMOR-NECROSIS-FACTOR-ALPHA INHIBITS CHOLESTEROL SIDE-CHAIN CLEAVAGE CYTOCHROME-P450 AND INSULIN- LIKE GROWTH-FACTOR-I GENE-EXPRESSION IN RAT LEYDIG-CELLS	16	0
6713	3	10365 1996 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 354(1):53-58 Lin WW; Wang CW SK&F 96365 inhibits carbachol induced phosphoinositide turnover in human neuroblastoma SH-SY5Y and rat cerebellar granule cells	2	0
6714	15	12443 2001 DRUG METABOLISM AND DISPOSITION 29(4):368-374 Lin Y; Lu P; Tang C; Mei Q; Sandig G; Rodrigues AD; Rushmore TH; Shou M Substrate inhibition kinetics for cytochrome P450-catalyzed reactions	13	3
6715	6	3905 1979 JOURNAL OF PHARMACOBIO-DYNAMICS 2(5):273-285 LIN YJ; AWAZU S; HANANO M INHIBITORY MECHANISM OF SULFAPHENAZOLE ON TOLBUTAMIDE ELIMINATION FROM PLASMA IN RAT	5	0
6716	3	5278 1985 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 240(1):226-235 LIND C FORMATION OF BENZO[A]PYRENE-3,6-QUINOL MONOGLUCURONIDE AND DIGLUCURONIDE IN RAT-LIVER MICROSOMES	29	2
6717	3	5301 1985 BIOCHEMICAL PHARMACOLOGY 34(6):895-897 LIND C RELATIONSHIP BETWEEN THE RATE OF REDUCTION OF BENZO(A)PYRENE- 3,6-QUINONE AND THE FORMATION OF BENZO(A)PYRENE-3,6-QUINOL GLUCURONIDES IN RAT-LIVER MICROSOMES	15	4
6718	9	7701 1991 METHODS IN ENZYMOLOGY 202():741-752 LINDBERG RLP; NEGISHI M MODULATION OF SPECIFICITY AND ACTIVITY IN MAMMALIAN CYTOCHROME- P-450	4	2
6719	5	2524 1974 EXPERIMENTAL AND MOLECULAR PATHOLOGY 21(3):313-321 LINDEBOR.T; GLAUMANN H EFFECT OF A CATATOXIC STEROID PREGNENOLONE-16ALPHA-CARBONITRILE ON RAT-LIVER MICROSOMAL SUBFRACTIONS	5	0
6720	15	4598 1982 DRUG METABOLISM REVIEWS 13(1):71-121 LINDEKE B THE NON-ENZYMATIC AND POSTENZYMATIC CHEMISTRY OF N-OXYGENATED MOLECULES	23	3
6721	3	3709 1978 XENOBIOTICA 8(6):341-348 LINDEKE B; HALLSTROM G; ANDERSON E; KARLEN B ENZYMIC OXIDATION ALPHA TO ACETYLENIC GROUP IN METABOLISM OF N- (5-PYRROLIDINOPENT-3-YNYL)-SUCCINIMIDE (BL14) INVITRO	13	1
6722	9	13055 2003 EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 33(6):493-499 Lindell M; Karlsson MO; Lennernas H; Pahlman L; Lang MA Variable expression of CYP and Pgp genes in the human small intestine	0	0
6723	14	13056 2003 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 28(1):41-48 Lindell M; Lang M; Lennernas H Expression of genes encoding for drug metabolising cytochrome P450 enzymes and P-glycoprotein in the rat small intestine; comparison to the liver	0	0
6724	1	70 1959 JOURNAL OF CELLULAR AND COMPARATIVE PHYSIOLOGY 53(1):93-117 LINDENMAYER A OXIDATIVE METABOLISM AND ABSORPTION SPECTRA OF ANAEROBICALLY GROWN YEAST - MANOMETRIC DATA AND ABSOLUTE ABSORPTION SPECTRA	19	5
6725	1	27 1958 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 78(1):66-82 LINDENMAYER A; ESTABROOK RW LOW-TEMPERATURE SPECTRAL STUDIES ON THE BIOSYNTHESIS OF CYTOCHROMES IN BAKERS YEAST	69	69
6726	6	308 1964 BIOCHIMICA ET BIOPHYSICA ACTA 93(3):445-& LINDENMAYER A; SMITH L CYTOCHROMES + OTHER PIGMENTS OF BAKERS YEAST GROWN AEROBICALLY + ANAEROBICALLY	110	43
6727	29	10625 1997 CLINICAL CHEMISTRY 43(2):254-266 Linder MW; Prough RA; Valdes R Pharmacogenetics: A laboratory tool for optimizing therapeutic efficiency	63	7
6728	4	11463 1999 ANNALS OF CLINICAL AND LABORATORY SCIENCE 29(2):140-149 Linder MW; Valdes R Fundamentals and applications of pharmacogenetics for the clinical laboratory	8	2
6729	11	11789 1999 MOLECULAR DIAGNOSIS 4(4):365-379 Linder MW; Valdes R Pharmacogenetics in the practice of laboratory medicine	9	0
6730	1	7088 1990 HEPATOLOGY 12(5):1092-1097 LINDROS KO; YUAN C; PENTTILA KE ROLE OF ETHANOL-INDUCIBLE CYTOCHROME-P-450 IIE1 IN CARBON- TETRACHLORIDE INDUCED DAMAGE TO CENTRILOBULAR HEPATOCYTES FROM ETHANOL-TREATED RATS	59	9
6731	4	632 1967 BIOCHEMISTRY 6(5):1271-& LINDSTED.G HYDROXYLATION OF GAMMA-BUTYROBETAINE TO CARNITINE IN RAT LIVER	89	0
6732	9	8568 1993 CHEMOSPHERE 27(11):2183-2195 LINDSTROMSEPPA P; FARMANFARMAIAN L; STEGEMAN J A VISUAL TEST FOR HEPATIC EROD ACTIVITY AS A MARKER FOR EXPOSURE TO AROMATIC AND HALOGENATED AROMATIC-HYDROCARBONS	1	0
6733	6	4753 1983 AQUATIC TOXICOLOGY 3(1):35-46 LINDSTROMSEPPA P; KOIVUSAARI U; HANNINEN O METABOLISM OF FOREIGN COMPOUNDS IN FRESH-WATER CRAYFISH (ASTACUS-ASTACUS L) TISSUES	23	2
6734	12	8904 1994 AQUATIC TOXICOLOGY 28(3-4):147-167 LINDSTROMSEPPA P; KORYTKO PJ; HAHN ME; STEGEMAN JJ UPTAKE OF WATERBORNE 3,3',4,4'-TETRACHLOROBIPHENYL AND ORGAN AND CELL-SPECIFIC INDUCTION OF CYTOCHROME P4501A IN ADULT AND LARVAL FATHEAD MINNOW PIMEPHALES-PROMELAS	25	7
6735	5	11445 1999 ADVANCES IN INORGANIC CHEMISTRY, VOL 47 47():83-157 Link TA The structures of Rieske and Rieske-type proteins	15	0
6736	2	10040 1996 BIOCHEMISTRY 35(23):7546-7552 Link TA; Hatzfeld OM; Unalkat P; Shergill JK; Cammack R; Mason JR Comparison of the ''Rieske'' [2Fe-2S] center in the bc1 complex and in bacterial dioxygenases by circular dichroism spectroscopy and cyclic voltammetry	29	2
6737	16	1726 1972 ANNUAL REVIEW OF MICROBIOLOGY 26():163-& LINNANE AW; LUKINS HB; NAGLEY P; HASLAM JM BIOGENESIS OF MITOCHONDRIA IN MICROORGANISMS	123	6
6738	1	186 1962 JOURNAL OF CELL BIOLOGY 13(2):345-& LINNANE AW; VITOLS E; NOWLAND PG STUDIES ON ORIGIN OF YEAST MITOCHONDRIA	149	14
6739	17	6366 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 268(1):152-160 LIPKA JJ; WASKELL LA METHOXYFLURANE ACTS AT THE SUBSTRATE BINDING-SITE OF CYTOCHROME-P450 LM2 TO INDUCE A DEPENDENCE ON CYTOCHROME-B5	5	4
6740	5	4999 1983 TOXICOLOGY 28(1-2):93-101 LIPPI A; CITTI L; GERVASI P; TURCHI G; BELLUCCI G; MASTRORILLI E METABOLISM OF 1,3-CYCLOHEXADIENE BY ISOLATED RAT-LIVER CELLS	1	0
6741	2	7801 1991 XENOBIOTICA 21(2):141-145 LIPPI A; GERVASI PG; BELLUCCI G; MARIONI F; LUZZANI F; VENTURA P EFFECT OF A TERPENOID, (-)-6-HYDROXY-4-(1-HYDROXY-1- METHYLETHYL)-1-CYCLOHEXENE-1-ETHANOL, ON DRUG-METABOLIZING- ENZYMES AND GLUTATHIONE CONTENT IN RAT-LIVER AND LUNG	0	0
6742	15	2185 1973 DRUG METABOLISM AND DISPOSITION 1(1):1-5 LIPSCOMB JD; GUNSALUS IC STRUCTURAL ASPECTS OF ACTIVE-SITE OF CYTOCHROME P-450CAM	9	4
6743	4	3123 1976 JOURNAL OF BIOLOGICAL CHEMISTRY 251(4):1116-1124 LIPSCOMB JD; SLIGAR SG; NAMTVEDT MJ; GUNSALUS IC AUTOOXIDATION AND HYDROXYLATION REACTIONS OF OXYGENATED CYTOCHROME P-450CAM	113	42
6744	8	3660 1978 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 4(1):107-121 LIPSKY MM; KLAUNIG JE; HINTON DE COMPARISON OF ACUTE RESPONSE TO POLYCHLORINATED BIPHENYL IN LIVER OF RAT AND CHANNEL CATFISH - BIOCHEMICAL AND MORPHOLOGICAL-STUDY	34	0
6745	2	12641 2001 SAR AND QSAR IN ENVIRONMENTAL RESEARCH 12(4):359-366 Lisitsa AV; Gusev SA; Karuzina II; Archakov AI; Koymans L Cytochrome P450 database	0	0
6746	3	8738 1993 JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY 17(1):33-40 LISSI EA; ROSENBLUTH H DISRUPTION EFFECTS OF CARBON-TETRACHLORIDE ON RAT-LIVER MICROSOMES	2	0
6747	3	3178 1976 PHARMACOLOGY & THERAPEUTICS PART B-GENERAL & SYSTEMATIC PHARMACOLOGY 2(1):219-246 LISSITZKY S BIOSYNTHESIS OF THYROID-HORMONES	15	0
6748	5	4577 1982 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 60(10):1247-1250 LISTER JL; VIRGO BB ANILINE AND HEXOBARBITAL HYDROXYLASES FROM RAT LUNG AND KIDNEY - NEITHER SEX DEPENDENT NOR INDUCIBLE WITH PHENOBARBITAL	6	0
6749	5	1834 1972 BIOCHIMICA ET BIOPHYSICA ACTA 273(1):52-& LISTON AJ; TOFT P EVIDENCE FOR ENOL INTERMEDIATES IN CYTOCHROME-P-450 MEDIATED STEROID HYDROXYLATIONS	2	0
6750	10	4538 1982 BIOCHEMICAL PHARMACOLOGY 31(9):1795-1798 LITTLE PJ; RYAN AJ INHIBITORS OF HEPATIC MIXED-FUNCTION OXIDASES .5. INHIBITION OF AMINOPYRINE N-DEMETHYLATION AND ENHANCEMENT OF ANILINE HYDROXYLATION BY BENZOXAZOLE DERIVATIVES	4	2
6751	12	4669 1982 JOURNAL OF MEDICINAL CHEMISTRY 25(6):622-626 LITTLE PJ; RYAN AJ INHIBITORS OF HEPATIC MIXED-FUNCTION OXIDASES .4. EFFECTS OF BENZIMIDAZOLE AND RELATED-COMPOUNDS ON ARYL-HYDROCARBON HYDROXYLASE-ACTIVITY FROM PHENOBARBITONE AND 3- METHYLCHOLANTHRENE INDUCED RATS	23	9
6752	1	795 1968 BIOCHEMISTRY 7(4):1560-& LITVAK S; AGOSIN M PROTEIN SYNTHESIS IN POLYSOMES FROM HOUSEFLIES AND EFFECT OF 2,2-BIS(P-CHLOROPHENYL)-1,1,1-TRICHLOROMETHANE	20	3
6753	7	5152 1984 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 16(8):943-946 LITWINSKA D; SZCZESNAKACZMAREK A; POPINIGIS J TRANSAMINATIVE PATHWAY OF GLUTAMATE OXIDATION IN ADRENAL-CORTEX MITOCHONDRIA	1	1
6754	15	10356 1996 MOLECULAR PHARMACOLOGY 50(4):781-788 Liu C; Zhuo XL; Gonzalez FJ; Ding XX Baculovirus-Mediated expression and characterization of rat CYP2A3 and human CYP2A6: Role in metabolic activation of nasal toxicants	38	15
6755	6	9912 1996 ACTA BIOCHIMICA ET BIOPHYSICA SINICA 28(5):471-478 Liu DL; Tomura D; Shoun H Cloning and expression of the cytochrome P-450nor2 cDNA from Cylindrocarpon tonkinense	0	0
6756	9	12686 2002 ANTICANCER RESEARCH 22(2A):863-868 Liu H; Baliga M; Baliga R Effect of cytochrome p450 2E1 inhibitors on cisplatin-induced cytotoxicity to renal proximal tubular epithelial cells	1	1
6757	16	13088 2003 KIDNEY INTERNATIONAL 63(5):1687-1696 Liu H; Baliga R Cytochrome P450 2E1 null mice provide novel protection against cisplatin-induced nephrotoxicity and apoptosis	0	0
6758	10	12894 2002 KIDNEY INTERNATIONAL 62(3):868-876 Liu H; Bigler SA; Henegar JR; Baliga R Cytochrome P4502B1 mediates oxidant injury in puromycin-induced nephrotic syndrome	1	1
6759	3	13093 2003 MOLECULAR CARCINOGENESIS 37(1):39-50 Liu JD; Wang YJ; Chen CH; Yu CF; Chen LC; Lin JK; Liang YC; Lin SY; Ho YS Molecular mechanisms of G(0)/G(1) cell-cycle arrest and apoptosis induced by terfenadine in human cancer cells	0	0
6760	14	13039 2003 DRUG METABOLISM AND DISPOSITION 31(4):412-420 Liu JG; Ericksen SS; Besspiata D; Fisher CW; Szklarz GD Characterization of substrate binding to cytochrome P450 1A1 using molecular modeling and kinetic analyses: Case of residue 382	0	0
6761	20	9949 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 327(1):167-173 Liu JP; He YA; Halpert JR Role of residue 480 in substrate specificity of cytochrome P450 2B5 and 2B11	15	8
6762	1	12635 2001 PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 28(3):372-376 Liu K; Sun J; Liu Y; Zhang QY; Kuang TY ESR studies on the superoxide radicals generated in photosystem II of higher plant	1	0
6763	9	10736 1997 INSECT MOLECULAR BIOLOGY 6(1):77-81 Liu N; Scott JG Phenobarbital induction of CYP6D1 is due to a trans acting factor on autosome 2 in house flies, Musca domestica	20	4
6764	12	2699 1975 BIOCHEMICAL PHARMACOLOGY 24(3):369-378 LIU SJ; RAMSEY RK; FALLON HJ EFFECTS OF ETHANOL ON HEPATIC MICROSOMAL DRUG-METABOLIZING- ENZYMES IN RAT	56	8
6765	8	11163 1998 DNA AND CELL BIOLOGY 17(5):461-470 Liu SQ; Park Y; Rivera-Rivera I; Li H; Kemper B Nuclear factor-1 motif and redundant regulatory elements comprise phenobarbital-responsive enhancer in CYP2B1/2	19	5
6766	4	12921 2002 ONCOLOGY REPORTS 9(2):327-329 Liu TC; Lin SF; Chen TP; Chang JG Polymorphism analysis of CYP3A5 in myeloid leukemia	1	1
6767	1	8223 1992 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 263(2):651-656 LIU Y; THURMAN RG POTENTIATION OF ADRIAMYCIN TOXICITY BY ETHANOL IN PERFUSED-RAT- LIVER	3	0
6768	12	5282 1985 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 241(2):397-402 LIU Z; FRANKLIN MR CYTOCHROME-P-450 LIGANDS - METYRAPONE REVISITED	11	5
6769	10	10829 1997 MOLECULAR ENDOCRINOLOGY 11(2):127-137 Liu Z; Simpson ER Steroidogenic factor 1 (SF-1) and SP1 are required for regulation of bovine CYP11A gene expression in bovine luteal cells and adrenal Y1 cells	71	2
6770	9	11787 1999 MOLECULAR AND CELLULAR ENDOCRINOLOGY 153(1-2):183-196 Liu Z; Simpson ER Molecular mechanism for cooperation between Sp1 and steroidogenic factor-1 (SF-1) to regulate bovine CYP11A gene expression	18	1
6771	2	5022 1984 ANALYTICAL BIOCHEMISTRY 142(2):340-346 LIU ZQ; FRANKLIN MR SEPARATION OF 4 GLUCURONIDES IN A SINGLE SAMPLE BY HIGH- PRESSURE LIQUID-CHROMATOGRAPHY AND ITS USE IN THE DETERMINATION OF UDP GLUCURONOSYLTRANSFERASE ACTIVITY TOWARD 4 AGLYCONES	37	21
6772	7	5126 1984 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 9(2):155-159 LIU ZQ; FRANKLIN MR CYTOCHROME-P-450 METABOLIC-INTERMEDIATE COMPLEX-FORMATION FROM PARA-AMINOBENZOIC ACID-ESTERS AND OTHER ARYLAMINES	4	0
6773	6	6897 1990 BIOCHEMICAL SOCIETY TRANSACTIONS 18(1):15-19 LIVINGSTONE DR CYTOCHROME-P-450 AND OXIDATIVE-METABOLISM IN INVERTEBRATES	30	10
6774	6	7512 1991 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 100(1-2):151-155 LIVINGSTONE DR TOWARDS A SPECIFIC INDEX OF IMPACT BY ORGANIC POLLUTION FOR MARINE-INVERTEBRATES	43	3
6775	16	8706 1993 JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY 57(3):195-211 LIVINGSTONE DR BIOTECHNOLOGY AND POLLUTION MONITORING - USE OF MOLECULAR BIOMARKERS IN THE AQUATIC ENVIRONMENT	129	7
6776	7	12102 2000 INTERNATIONAL JOURNAL OF ENVIRONMENT AND POLLUTION 13(1-6):56-91 Livingstone DR; Chipman JK; Lowe DM; Minier C; Mitchelmore CL; Moore MN; Peters LD; Pipe RK Development of biomarkers to detect the effects of organic pollution on aquatic invertebrates: recent molecular, genotoxic, cellular and immunological studies on the common mussel (Mytilus edulis L.) and other mytilids	12	0
6777	12	10477 1997 AQUATIC TOXICOLOGY 38(4):205-224 Livingstone DR; Nasci C; Sole M; DaRos L; OHara SCM; Peters LD; Fossato V; Wootton AN; Goldfarb PS Apparent induction of a cytochrome P450 with immunochemical similarities to CYP1A in digestive gland of the common mussel (Mytilus galloprovincialis L) with exposure to 2,2',3,4,4',5'- hexachlorobiphenyl and Arochlor 1254	30	7
6778	2	6787 1989 XENOBIOTICA 19(10):1037-1039 LIVINGSTONE DR; STEGEMAN JJ CYTOCHROME-P-450 FORMS AND FUNCTIONS IN ANIMALS	6	3
6779	3	4675 1982 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 17(6):631-638 LLANO M; KOLANOWSKI J; ORTEGA N; CRABBE J CHANGES IN CORTICOSTEROID SECRETORY PATTERN INDUCED BY PROLONGED CORTICOTROPIN TREATMENT IN THE RABBIT	18	4
6780	8	10940 1998 ADVANCES IN MICROBIAL PHYSIOLOGY, VOL 39 39():291-338 Lloyd D Circadian and ultradian clock-controlled rhythms in unicellular microorganisms	13	0
6781	1	4701 1982 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79(12):3785-3788 LLOYD D; EDWARDS SW; FRY JC TEMPERATURE-COMPENSATED OSCILLATIONS IN RESPIRATION AND CELLULAR PROTEIN-CONTENT IN SYNCHRONOUS CULTURES OF ACANTHAMOEBA-CASTELLANII	36	2
6782	4	842 1968 EXPERIMENTAL CELL RESEARCH 51(2-3):291-& LLOYD D; GRIFFITH.AJ ISOLATION OF MITOCHONDRIA FROM AMOEBA HARTMANELLA CASTELLANII NEFF	24	0
6783	4	8355 1992 YEAST 8(4):291-301 LLOYD D; JAMES CJ; MAITRA PK MUTATIONS IN PHOSPHOFRUCTOKINASES ALTER THE CONTROL CHARACTERISTICS OF GLYCOLYSIS INVIVO IN SACCHAROMYCES- CEREVISIAE	7	0
6784	1	13060 2003 FEMS YEAST RESEARCH 3(4):333-339 Lloyd D; Lemar KA; Salgado LEJ; Gould TM; Murray DB Respiratory oscillations in yeast: mitochondrial reactive oxygen species, apoptosis and time; a hypothesis	0	0
6785	15	7461 1991 BIOLOGICAL REVIEWS OF THE CAMBRIDGE PHILOSOPHICAL SOCIETY 66(3):275-299 LLOYD D; STUPFEL M THE OCCURRENCE AND FUNCTIONS OF ULTRADIAN RHYTHMS	26	2
6786	6	7794 1991 TOXICOLOGY LETTERS 55(1):65-75 LLOYD SA; FRANKLIN MR MODULATION OF CARBON-TETRACHLORIDE HEPATOTOXICITY AND XENOBIOTIC-METABOLIZING ENZYMES BY CORTICOSTERONE PRETREATMENT, ADRENALECTOMY AND SHAM SURGERY	6	0
6787	2	2399 1974 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 163(1):185-190 LLOYD WJ; HARRISON R INTERACTION OF DEOXY AND DEOXYFLUORO-SUBSTRATE ANALOGS AND RELATED COMPOUNDS WITH SN-GLYCEROL-3-PHOSPHATE DEHYDROGENASE OF LOCUST FLIGHT-MUSCLE MITOCHONDRIA	6	0
6788	15	12925 2002 PHARMACOGENETICS 12(5):367-374 Lo-Guidice JM; Allorge D; Cauffiez C; Chevalier D; Lafitte JJ; Lhermitte M; Broly F Genetic polymorphism of the human cytochrome P450CYP4B1: evidence for a non-functional allelic variant	3	0
6789	5	8504 1993 BIOCHEMISTRY-MOSCOW 58(10):1118-1124 LOBANOV NA; HENSEY CE; USANOV SA; AZZI A PHOSPHORYLATION OF CYTOCHROME P-450(SCC) BY PROTEIN-KINASE-C - PROTECTIVE EFFECTS OF ADRENODOXIN AND CYTOCHROME B(5)	1	0
6790	7	6924 1990 BIOCHEMISTRY-MOSCOW 55(6):791-795 LOBANOV NA; VLASOVA TM; ADAMOVICH TB COMPARATIVE-STUDY OF BOVINE ADRENODOXIN AND RENOREDOXIN	0	0
6791	7	6360 1989 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 29():145-163 LOCK EA; MITCHELL AM; ELCOMBE CR BIOCHEMICAL-MECHANISMS OF INDUCTION OF HEPATIC PEROXISOME PROLIFERATION	354	41
6792	10	5998 1987 XENOBIOTICA 17(4):513-522 LOCK EA; STONARD MD; ELCOMBE CR THE INDUCTION OF OMEGA-OXIDATION AND BETA-OXIDATION OF FATTY- ACIDS AND EFFECT ON ALPHA-2U-GLOBULIN CONTENT IN THE LIVER AND KIDNEY OF RATS ADMINISTERED 2,2,4-TRIMETHYLPENTANE	14	3
6793	1	4325 1981 CANADIAN MEDICAL ASSOCIATION JOURNAL 124(8):993-999 LOCKHAT D; KATZ SS; LISBONA R; MISHKIN S ORAL-CONTRACEPTIVES AND LIVER-DISEASE .10.	7	0
6794	8	12204 2000 PARASITOLOGY 120():399-407 Lockyer AE; Jones CS; Noble LR; Rollinson D Use of differential display to detect changes in gene expression in the intermediate snail host Biomphalaria glabrata upon infection with Schistosoma mansoni	9	0
6795	2	1615 1971 JOURNAL OF BIOLOGICAL CHEMISTRY 246(3):791-& LODE ET; COON MJ ENZYMATIC OMEGA-OXIDATION .5. FORMS OF PSEUDOMONAS-OLEOVORANS RUBREDOXIN CONTAINING ONE OR 2 IRON ATOMS - STRUCTURE AND FUNCTION IN OMEGA-HYDROXYLATION	90	12
6796	5	7616 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(5):3016-3021 LOEBER G; INFANTE AA; MAURERFOGY I; KRYSTEK E; DWORKIN MB HUMAN NAD+-DEPENDENT MITOCHONDRIAL MALIC ENZYME - CDNA CLONING, PRIMARY STRUCTURE, AND EXPRESSION IN ESCHERICHIA-COLI	45	4
6797	9	8960 1994 BIOCHEMICAL JOURNAL 304():687-692 LOEBER G; MAURERFOGY I; SCHWENDENWEIN R PURIFICATION, CDNA CLONING AND HETEROLOGOUS EXPRESSION OF THE HUMAN MITOCHONDRIAL NADP(+)-DEPENDENT MALIC ENZYME	7	2
6798	14	8641 1993 GASTROENTEROLOGY 104(1):203-216 LOEPER J; DESCATOIRE V; MAURICE M; BEAUNE P; BELGHITI J; HOUSSIN D; BALLET F; FELDMANN G; GUENGERICH FP; PESSAYRE D CYTOCHROMES-P-450 IN HUMAN HEPATOCYTE PLASMA-MEMBRANE - RECOGNITION BY SEVERAL AUTOANTIBODIES	86	16
6799	10	7086 1990 HEPATOLOGY 11(5):850-858 LOEPER J; DESCATOIRE V; MAURICE M; BEAUNE P; FELDMANN G; LARREY D; PESSAYRE D PRESENCE OF FUNCTIONAL CYTOCHROME-P-450 ON ISOLATED RAT HEPATOCYTE PLASMA-MEMBRANE	57	11
6800	3	10321 1996 JOURNAL OF PLANT PHYSIOLOGY 149(5):633-635 Loerwald B; Clemens S; Barz W Purification and characterization of the NADPH-cytochrome P-450 (cytochrome c) reductase from chickpea	1	0

#	Cited nodes	Nodes / Authors	GCS	LCS
6801	5	3375 1977 INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY ():225-244 LOEW GH; HJELMELAND LM; KIRCHNER RF MODELS FOR ENZYMATICALLY ACTIVE STATE OF CYTOCHROME-P-450	1	1
6802	2	1700 1971 THEORETICA CHIMICA ACTA 23(3):239-& LOEW GH; STEINBER.DA MOLECULAR ORBITAL CALCULATIONS OF ACTIVE SITE COMPLEX OF 2 IRON FERREDOXINS .1. ENERGY-CONFORMATION STUDIES	11	4
6803	3	2010 1972 THEORETICA CHIMICA ACTA 26(2):107-& LOEW GH; STEINBER.DA MOLECULAR-ORBITAL CALCULATIONS OF ACTIVE-SITE COMPLEX OF 2 IRON FERREDOXINS .2. ELECTRON-DISTRIBUTION, MAGNETIC-MOMENT, FIELD GRADIENTS AND ELECTRONIC-SPECTRA OF OXIDIZED STATE	9	2
6804	12	7267 1990 PHARMACOLOGY & TOXICOLOGY 66():4-31 LOFT S METRONIDAZOLE AND ANTIPYRINE AS PROBES FOR THE STUDY OF FOREIGN COMPOUND METABOLISM	2	0
6805	6	7407 1991 BIOCHEMICAL PHARMACOLOGY 41(8):1127-1134 LOFT S; OTTON SV; LENNARD MS; TUCKER GT; POULSEN HE CHARACTERIZATION OF METRONIDAZOLE METABOLISM BY HUMAN LIVER- MICROSOMES	22	4
6806	12	7269 1990 PHARMACOLOGY & TOXICOLOGY 67(2):101-108 LOFT S; POULSEN HE PREDICTION OF XENOBIOTIC METABOLISM BY NONINVASIVE METHODS	11	2
6807	43	11367 1998 PHARMACOLOGICAL REVIEWS 50(1):107-141 Lohr JW; Willsky GR; Acara MA Renal drug metabolism	22	3
6808	10	8498 1993 BIOCHEMISTRY 32(43):11530-11538 LOIDA PJ; SLIGAR SG MOLECULAR RECOGNITION IN CYTOCHROME-P-450 - MECHANISM FOR THE CONTROL OF UNCOUPLING REACTIONS	74	28
6809	6	1241 1970 BIOCHEMICAL PHARMACOLOGY 19(7):2317-& LOMBROZO L; MITOMA C EFFECT OF CAFFEINE ON HEPATIC MICROSOMAL CYTOCHROME-P-450	28	7
6810	5	999 1969 BIOCHEMICAL JOURNAL 115(5):P26-& LONG RF INDUCTION OF DRUG-METABOLIZING ENZYMES AND CYTOCHROME P-450	4	1
6811	1	3374 1977 INTERNATIONAL JOURNAL OF BIOMETEOROLOGY 21(2):179-187 LONGMUIR IS; PASHKO L ROLE OF FACILITATED DIFFUSION OF OXYGEN IN TISSUE HYPOXIA	5	0
6812	4	3233 1977 AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 129(1):69-103 LONGO LD BIOLOGICAL EFFECTS OF CARBON-MONOXIDE ON PREGNANT WOMAN, FETUS, AND NEWBORN-INFANT	250	1
6813	20	10543 1997 BIOCHEMICAL JOURNAL 323():65-70 Longo V; Amato G; Santucci A; Gervasi PG Purification and characterization of three constitutive cytochrome P-450 isoforms from bovine olfactory epithelium	10	7
6814	3	5501 1985 TOXICOLOGY LETTERS 29(1):33-37 LONGO V; CITTI L; GERVASI PG HEPATIC-MICROSOMAL METABOLISM OF ISOPRENE IN VARIOUS RODENTS	18	0
6815	5	6327 1988 TOXICOLOGY LETTERS 44(3):289-297 LONGO V; CITTI L; GERVASI PG BIOTRANSFORMATION ENZYMES IN NASAL-MUCOSA AND LIVER OF SPRAGUE- DAWLEY RATS	36	12
6816	12	8480 1993 BIOCHEMICAL PHARMACOLOGY 46(11):1945-1951 LONGO V; INGELMANSUNDBERG M ACETONE-DEPENDENT REGULATION OF CYTOCHROMES P4502E1 AND P4502B1 IN RAT NASAL-MUCOSA	23	8
6817	7	7603 1991 JOURNAL OF BIOCHEMICAL TOXICOLOGY 6(2):123-128 LONGO V; MAZZACCARO A; NALDI F; GERVASI PG DRUG-METABOLIZING-ENZYMES IN LIVER, OLFACTORY, AND RESPIRATORY EPITHELIUM OF CATTLE	33	9
6818	1	11320 1998 MEDIATORS OF INFLAMMATION 7(2):85-91 Longo WE; Damore LJ; Mazuski JE; Smith GS; Panesar N; Kaminski DL The role of cyclooxygenase-1 and cyclooxygenase-2 in lipopolysaccharide and interleukin-1 stimulated enterocyte prostanoid formation	10	0
6819	7	2184 1973 DRUG INTELLIGENCE & CLINICAL PHARMACY 7(6):263-270 LONGSHAW RN INHIBITION OF HEPATIC DRUG-METABOLISM	5	0
6820	10	8242 1992 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 43(8):1107-1116 LOPER JC CYTOCHROME P450 LANOSTEROL 14-ALPHA-DEMETHYLASE (CYP51) - INSIGHTS FROM MOLECULAR GENETIC-ANALYSIS OF THE ERG11-GENE IN SACCHAROMYCES-CEREVISIAE	9	4
6821	5	11088 1998 BRITISH JOURNAL OF PHARMACOLOGY 125(2):309-318 Lopes CMB; Franks NP; Lieb WR Actions of general anaesthetics and arachidonic acid pathway inhibitors on K+ currents activated by volatile anaesthetics and FMRFamide in molluscan neurones	14	0
6822	16	10459 1997 ACTAS LUSO-ESPANOLAS DE NEUROLOGIA PSIQUIATRIA Y CIENCIAS AFINES 25(6):397-409 Lopez-Munoz F; Alamo C; Cuenca E; Rubio G Effect of antidepressant drugs on cytochrome P-450 isoenzymes and its clinical relevance: differential profile	1	0
6823	3	2792 1975 ENDOKRINOLOGIE 66(3):250-254 LOPEZDELPINO V; BOLT HM THIOACETAMIDE-POISONED RAT - MODEL FOR ENDOCRINOLOGICAL INVESTIGATIONS OF ESTROGEN METABOLISM IN CHRONIC LIVER-INJURY	4	0
6824	3	7231 1990 MOLECULAR ENDOCRINOLOGY 4(12):1850-1855 LORENCE MC; CORBIN CJ; KAMIMURA N; MAHENDROO MS; MASON JI STRUCTURAL-ANALYSIS OF THE GENE ENCODING HUMAN 3-BETA- HYDROXYSTEROID DEHYDROGENASE DELTA-5-]4-ISOMERASE	52	4
6825	3	7043 1990 ENDOCRINOLOGY 126(5):2493-2498 LORENCE MC; MURRY BA; TRANT JM; MASON JI HUMAN 3-BETA-HYDROXYSTEROID DEHYDROGENASE DELTA-5-]4-ISOMERASE FROM PLACENTA - EXPRESSION IN NONSTEROIDOGENIC CELLS OF A PROTEIN THAT CATALYZES THE DEHYDROGENATION ISOMERIZATION OF C21 AND C19 STEROIDS	157	17
6826	3	7719 1991 MOLECULAR AND CELLULAR ENDOCRINOLOGY 80(1-3):21-31 LORENCE MC; NAVILLE D; GRAHAMLORENCE SE; MACK SO; MURRY BA; TRANT JM; MASON JI 3-BETA-HYDROXYSTEROID DEHYDROGENASE DELTA-5-]4-ISOMERASE EXPRESSION IN RAT AND CHARACTERIZATION OF THE TESTIS ISOFORM	33	3
6827	9	6918 1990 BIOCHEMISTRY 29(42):9819-9824 LORENCE MC; TRANT JM; CLARK BJ; KHYATT B; MASON JI; ESTABROOK RW; WATERMAN MR CONSTRUCTION AND EXPRESSION OF HUMAN-BOVINE P45017-ALPHA CHIMERIC PROTEINS - EVIDENCE FOR DISTINCT TERTIARY STRUCTURES IN THE SAME P450 FROM 2 DIFFERENT SPECIES	21	21
6828	10	6389 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 273(1):79-88 LORENCE MC; TRANT JM; MASON JI; BHASKER CR; FUJIIKURIYAMA Y; ESTABROOK RW; WATERMAN MR EXPRESSION OF A FULL-LENGTH CDNA-ENCODING BOVINE ADRENAL CYTOCHROME-P450C21	22	22
6829	1	3809 1979 CANCER RESEARCH 39(8):3194-3198 LORENTZEN RJ; LESKO SA; MCDONALD K; TSO POP TOXICITY OF METABOLIC BENZO(A)PYRENEDIONES TO CULTURED-CELLS AND THE DEPENDENCE UPON MOLECULAR-OXYGEN	57	7
6830	5	7308 1990 TOXICOLOGY AND APPLIED PHARMACOLOGY 106(1):53-62 LORENZEN A; OKEY AB DETECTION AND CHARACTERIZATION OF [H-3] 2,3,7,8- TETRACHLORODIBENZO-PARA-DIOXIN BINDING TO AH RECEPTOR IN A RAINBOW-TROUT HEPATOMA-CELL LINE	76	15
6831	9	6711 1989 MOLECULAR PHARMACOLOGY 35(5):610-616 LORR NA; BLOOM SE; PARK SS; GELBOIN HV; MILLER H; FRIEDMAN FK EVIDENCE FOR A PCN-P450 ENZYME IN CHICKENS AND COMPARISON OF ITS DEVELOPMENT WITH THAT OF OTHER PHENOBARBITAL-INDUCIBLE FORMS	28	12
6832	1	12885 2002 JOURNAL OF PROTEIN CHEMISTRY 21(2):97-104 Lorrai A; Padiglia A; Medda R; Bellelli A; Arcovito A; Floris G Aminoglycosides as substrates and inhibitors of peroxidases: A possible role of these antibiotics against myeloperoxidase- dependent cytotoxicity	0	0
6833	1	1974 1972 MOLECULAR PHARMACOLOGY 8(2):197-& LORUSSO DJ; SUTTIE JW WARFARIN BINDING TO MICROSOMES ISOLATED FROM NORMAL AND WARFARIN-RESISTANT RAT-LIVER	28	1
6834	6	3760 1979 BIOCHEMICAL JOURNAL 182(1):133-147 LORUSSO M; CAPUANO F; BOFFOLI D; STEFANELLI R; PAPA S MECHANISM OF TRANSMEMBRANE DELTA-MU-H+ GENERATION IN MITOCHONDRIA BY CYTOCHROME-C OXIDASE	43	2
6835	5	2753 1975 BRAIN RESEARCH 88(1):15-36 LOTHMAN E; LAMANNA J; CORDINGLEY G; ROSENTHAL M; SOMJEN G RESPONSES OF ELECTRICAL POTENTIAL, POTASSIUM LEVELS, AND OXIDATIVE METABOLIC-ACTIVITY OF CEREBRAL NEOCORTEX OF CATS	148	2
6836	6	5005 1983 TOXICOLOGY LETTERS 19(1-2):51-56 LOTLIKAR PD; HONG YS; COOPER DY LIGHT REVERSAL OF CARBON-MONOXIDE INHIBITION OF 2- ACETYLAMINOFLUORENE N-HYDROXYLATION AND RING-HYDROXYLATION BY LIVER-MICROSOMES FROM 3-METHYLCHOLANTHRENE PRETREATED HAMSTERS	1	0
6837	11	10456 1996 YEAST 12(6):565-575 Lottermoser K; Schunck WH; Asperger O Cytochromes P450 of the sophorose lipid-producing yeast Candida apicola: Heterogeneity and polymerase chain reaction-mediated cloning of two genes	5	2
6838	17	8909 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 309(1):52-57 LOU ZS; HE YA; HALPERT JR ROLE OF RESIDUE-363 AND RESIDUE-206 IN CONVERSION OF CYTOCHROME-P450 2B1 FROM A STEROID 16-HYDROXYLASE TO A 15- ALPHA-HYDROXYLASE	0	0
6839	30	11816 1999 PHARMACOGENETICS 9(1):61-70 Louerat-Oriou B; Flinois JP; Beaune PH; Pompon D High yield purification and characterization of engineered human P450 1A2 and generation of immuno-inhibitor antibodies	0	0
6840	24	11207 1998 EUROPEAN JOURNAL OF BIOCHEMISTRY 258(3):1040-1049 Louerat-Oriou B; Perret A; Pompon D Differential redox and electron-transfer properties of purified yeast, plant and human NADPH-cytochrome P-450 reductases highly modulate cytochrome P-450 activities	7	0
6841	23	11966 2000 BIOCHEMISTRY 39(49):15110-15120 Loughran PA; Roman LJ; Aitken AE; Miller RT; Masters BSS Identification of unique amino acids that modulate CYP4A7 activity	6	3
6842	15	12318 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 385(2):311-321 Loughran PA; Roman LJ; Miller RT; Masters BSS The kinetic and spectral characterization of the E-coli- expressed mammalian CYP4A7: Cytochrome b(5) effects vary with substrate	11	10
6843	12	8860 1993 TOXICOLOGY AND APPLIED PHARMACOLOGY 118(2):169-176 LOUIS CA; SINCLAIR JF; WOOD SG; LAMBRECHT LK; SINCLAIR PR; SMITH EL SYNERGISTIC INDUCTION OF CYTOCHROME-P450 BY ETHANOL AND ISOPENTANOL IN CULTURES OF CHICK-EMBRYO AND RAT HEPATOCYTES	12	6
6844	16	9249 1994 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 269(2):838-845 LOUIS CA; WOOD SG; KOSTRUBSKY V; SINCLAIR PR; SINCLAIR JF SYNERGISTIC INCREASES IN RAT HEPATIC CYTOCHROME P450S BY ETHANOL AND ISOPENTANOL	30	4
6845	13	10993 1998 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 360(2):239-247 Louis CA; Wood SG; Walton HS; Sinclair PR; Sinclair JF Mechanism of the synergistic induction of CYP2H by isopentanol plus ethanol: Comparison to glutethimide and relation to induction of 5-aminolevulinate synthase	3	0
6846	1	1865 1972 CLINICAL TOXICOLOGY 5(3):387-& LOUISFER.RT; LAL H; FULLER GC AMPHETAMINE INHIBITION OF HEPATIC DRUG-METABOLISM - EVIDENCE FOR A COMPETITIVE MECHANISM	0	0
6847	9	11818 1999 PHARMACOGENETICS 9(2):239-250 Lovell DP; van Iersel M; Walters DG; Price RJ; Lake BG Genetic variation in the metabolism of coumarin in mouse liver	3	0
6848	3	11346 1998 NEUROLOGY 51(6):1562-1566 Lovell MA; Xie C; Markesbery WR Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease	40	0
6849	2	1729 1972 ARCHIV FUR MIKROBIOLOGIE 85(4):355-& LOWDON MJ; STEWART PR; GORDON PA REGULATION OF SYNTHESIS OF MITOCHONDRIAL ENZYMES AND CYTOCHROMES - DISTINCTION BETWEEN CATABOLITE REPRESSION AND ANAEROBIOSIS IN SACCHAROMYCES-CEREVISIAE	11	1
6850	7	896 1968 JOURNAL OF BIOLOGICAL CHEMISTRY 243(14):3940-& LOWENSTE.JM; CHANCE B EFFECT OF HYDROGEN IONS ON CONTROL OF MITOCHONDRIAL RESPIRATION	20	0
6851	3	140 1961 JOURNAL OF THEORETICAL BIOLOGY 1(1):98-& LOWENSTEIN JM REDUCTIONS AND OXIDATIONS IN MAMMALIAN BIOSYNTHESES	37	4
6852	9	3501 1978 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 83(2):747-753 LOWERY GL; BIDLACK WR MULTIPLE DRUG-METABOLISM IN ISOLATED HEPATOCYTES - ENHANCEMENT OF ANILINE HYDROXYLATION	11	3
6853	11	4451 1981 PROCEEDINGS OF THE WESTERN PHARMACOLOGY SOCIETY 24():141-145 LOWERY GL; BIDLACK WR MICROSOMAL AND PARENCHYMAL-CELL MODELS IN MULTIPLE-DRUG METABOLISM	0	0
6854	2	3686 1978 PROCEEDINGS OF THE WESTERN PHARMACOLOGY SOCIETY 21():345-351 LOWERY GL; WOLFF DG; BIDLACK WR ISOLATED HEPATOCYTES AS A CELLULAR MODEL FOR STUDYING DRUG- METABOLISM	7	3
6855	16	8024 1992 CLINICAL PHARMACOLOGY & THERAPEUTICS 51(3):229-238 LOWN K; KOLARS J; TURGEON K; MERION R; WRIGHTON SA; WATKINS PB THE ERYTHROMYCIN BREATH TEST SELECTIVELY MEASURES P450IIIA IN PATIENTS WITH SEVERE LIVER-DISEASE	80	13
6856	24	9095 1994 DRUG METABOLISM AND DISPOSITION 22(6):947-955 LOWN KS; KOLARS JC; THUMMEL KE; BARNETT JL; KUNZE KL; WRIGHTON SA; WATKINS PB INTERPATIENT HETEROGENEITY IN EXPRESSION OF CYP3A4 AND CYP3A5 IN SMALL-BOWEL - LACK OF PREDICTION BY THE ERYTHROMYCIN BREATH TEST	175	31
6857	18	9586 1995 CLINICAL PHARMACOLOGY & THERAPEUTICS 57(1):16-24 LOWN KS; THUMMEL KE; BENEDICT PE; SHEN DD; TURGEON DK; BERENT S; WATKINS PB THE ERYTHROMYCIN BREATH TEST PREDICTS THE CLEARANCE OF MIDAZOLAM	77	13
6858	31	3101 1976 FEDERATION PROCEEDINGS 35(13):2460-2463 LU AYH LIVER MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM - FUNCTIONAL COMPONENTS AND THEIR PROPERTIES	88	20
6859	2	885 1968 JOURNAL OF BIOLOGICAL CHEMISTRY 243(6):1331-& LU AYH; COON MJ ROLE OF HEMOPROTEIN P-450 IN FATTY ACID OMEGA-HYDROXYLATION IN A SOLUBLE ENZYME SYSTEM FROM LIVER MICROSOMES	463	225
6860	5	5246 1984 XENOBIOTICA 14(1-2):19-26 LU AYH; HARADA N; MIWA GT RATE-LIMITING STEPS IN CYTOCHROME-P-450-CATALYZED REACTIONS - STUDIES ON ISOTOPE EFFECTS IN THE O-DE-ETHYLATION OF 7- ETHOXYCOUMARIN	14	4
6861	4	3397 1977 JOURNAL OF BIOLOGICAL CHEMISTRY 252(11):3715-3723 LU AYH; JERINA DM; LEVIN W LIVER MICROSOMAL EPOXIDE HYDRASE - HYDRATION OF ALKENE AND ARENE OXIDES BY MEMBRANE-BOUND AND PURIFIED ENZYMES	113	9
6862	17	1118 1969 JOURNAL OF BIOLOGICAL CHEMISTRY 244(13):3714-& LU AYH; JUNK KW; COON MJ RESOLUTION OF CYTOCHROME P-450-CONTAINING OMEGA-HYDROXYLATION SYSTEM OF LIVER MICROSOMES INTO 3 COMPONENTS	429	190
6863	17	1467 1971 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 42(6):1200-& LU AYH; KUNTZMAN R; WEST S; CONNEY AH RECONSTITUTED LIVER MICROSOMAL ENZYME SYSTEM THAT HYDROXYLATES DRUGS, OTHER FOREIGN COMPOUNDS AND ENDOGENOUS SUBSTRATES .1. DETERMINATION OF SUBSTRATE SPECIFICITY BY CYTOCHROME P-450 AND P-448 FRACTIONS	132	55
6864	54	2462 1974 BIOCHIMICA ET BIOPHYSICA ACTA 344(2):205-240 LU AYH; LEVIN W RESOLUTION AND RECONSTITUTION OF LIVER MICROSOMAL HYDROXYLATION SYSTEM	252	87
6865	27	2042 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):156-174 LU AYH; LEVIN W; WEST S; JACOBSON M; RYAN D; KUNTZMAN R; CONNEY AH ROLE OF CYTOCHROME-P-450 AND P-448 IN DRUG AND STEROID HYDROXYLATIONS	44	15
6866	26	2278 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(2):456-460 LU AYH; LEVIN W; WEST SB; JACOBSON M; RYAN D; KUNTZMAN R; CONNEY AH RECONSTITUTED LIVER MICROSOMAL ENZYME-SYSTEM THAT HYDROXYLATES DRUGS, OTHER FOREIGN COMPOUNDS, AND ENDOGENOUS SUBSTRATES .6. DIFFERENT SUBSTRATE SPECIFICITIES OF CYTOCHROME-P-450 FRACTIONS FROM CONTROL AND PHENOBARBITAL-TREATED RATS	132	46
6867	14	1754 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 153(1):294-& LU AYH; LEVIN W; WEST SB; KUNTZMAN R; JACOBSON M RECONSTITUTED LIVER MICROSOMAL ENZYME-SYSTEM THAT HYDROXYLATES DRUGS, OTHER FOREIGN COMPOUNDS, AND ENDOGENOUS SUBSTRATES .4. HYDROXYLATION OF ANILINE	50	24
6868	13	985 1969 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 36(4):545-& LU AYH; STROBEL HW; COON MJ HYDROXYLATION OF BENZPHETAMINE AND OTHER DRUGS BY A SOLUBILIZED FORM OF CYTOCHROME P-450 FROM LIVER MICROSOMES - LIPID REQUIREMENT FOR DRUG DEMETHYLATION	142	57
6869	21	1385 1970 MOLECULAR PHARMACOLOGY 6(3):213-& LU AYH; STROBEL HW; COON MJ PROPERTIES OF A SOLUBILIZED FORM OF CYTOCHROME P-450-CONTAINING MIXED-FUNCTION OXIDASE OF LIVER MICROSOMES	176	81
6870	30	1926 1972 JOURNAL OF BIOLOGICAL CHEMISTRY 247(6):1727-& LU AYH; WEST S; CONNEY AH; KUNTZMAN R; JACOBSON M RECONSTITUTED LIVER MICROSOMAL ENZYME-SYSTEM THAT HYDROXYLATES DRUGS, OTHER FOREIGN COMPOUNDS, AND ENDOGENOUS SUBSTRATES .2. ROLE OF CYTOCHROME-P-450 AND P-448 FRACTIONS IN DRUG AND STEROID HYDROXYLATIONS	373	140
6871	8	1752 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 152(2):457-& LU AYH; WEST S; SOMOGYI A; CONNEY AH; KUNTZMAN R PREGNENOLONE-16ALPHA-CARBONITRILE - NEW TYPE OF INDUCER OF DRUG-METABOLIZING ENZYMES	214	63
6872	17	1979 1972 MOLECULAR PHARMACOLOGY 8(5):490-& LU AYH; WEST SB RECONSTITUTED LIVER MICROSOMAL ENZYME-SYSTEM THAT HYDROXYLATES DRUGS, OTHER FOREIGN COMPOUNDS, AND ENDOGENOUS SUBSTRATES .3. PROPERTIES OF RECONSTITUTED 3,4-BENZPYRENE HYDROXYLASE SYSTEM	88	41
6873	61	3668 1978 PHARMACOLOGY & THERAPEUTICS PART A-CHEMOTHERAPY TOXICOLOGY AND METABOLIC INHIBITORS 2(2):337-358 LU AYH; WEST SB RECONSTITUTED MAMMALIAN MIXED-FUNCTION OXIDASES - REQUIREMENTS, SPECIFICITIES AND OTHER PROPERTIES	147	51
6874	52	3934 1979 PHARMACOLOGICAL REVIEWS 31(4):277-295 LU AYH; WEST SB MULTIPLICITY OF MAMMALIAN MICROSOMAL CYTOCHROMES P-450	7	3
6875	15	2188 1973 DRUG METABOLISM AND DISPOSITION 1(1):29-39 LU AYH; WEST SB; RYAN D; LEVIN W CHARACTERIZATION OF PARTIALLY PURIFIED CYTOCHROMES P-450 AND P- 448 FROM RAT-LIVER MICROSOMES	26	0
6876	31	2562 1974 JOURNAL OF BIOLOGICAL CHEMISTRY 249(21):6701-6709 LU AYH; WEST SB; VORE M; RYAN D; LEVIN W ROLE OF CYTOCHROME-B5 IN HYDROXYLATION BY A RECONSTITUTED CYTOCHROME P-450-CONTAINING SYSTEM	120	86
6877	1	7501 1991 CHEMICO-BIOLOGICAL INTERACTIONS 78(1):77-84 LU H; LIU GT EFFECT OF DIBENZO[A,C]CYCLOOCTENE LIGNANS ISOLATED FROM FRUCTUS-SCHIZANDRAE ON LIPID-PEROXIDATION AND ANTIOXIDATIVE ENZYME-ACTIVITY	19	0
6878	2	8309 1992 PLANTA MEDICA 58(4):311-313 LU H; LIU GT ANTIOXIDANT ACTIVITY OF DIBENZOCYCLOOCTENE LIGNANS ISOLATED FROM SCHISANDRACEAE	23	0
6879	8	9465 1995 ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY 28(1):79-90 LU KH; BRADFIELD JY; KEELEY LL HYPERTREHALOSEMIC HORMONE-REGULATED GENE-EXPRESSION FOR CYTOCHROME P4504C1 IN THE FAT-BODY OF THE COCKROACH, BLABERUS- DISCOIDALIS	6	2
6880	6	11688 1999 INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 29(8):667-673 Lu KH; Bradfield JY; Keeley LL Juvenile hormone inhibition of gene expression for cytochrome P4504C1 in adult females of the cockroach, Blaberus discoidalis	2	1
6881	15	10480 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 337(1):1-7 Lu P; Alterman MA; Chaurasia CS; Bambal RB; Hanzlik RP Heme-coordinating analogs of lauric acid as inhibitors of fatty acid omega-hydroxylation	11	7
6882	2	6047 1988 ARCHIVES OF MICROBIOLOGY 149(4):303-307 LU WP; KELLY DP CHEMOLITHOTROPHIC ATP SYNTHESIS AND NAD(P) REDUCTION IN THIOBACILLUS-TEPIDARIUS AND THIOBACILLUS-VERSUTUS	7	0
6883	3	3859 1979 INTERNATIONAL JOURNAL OF CANCER 23(3):353-357 LUBET RA; CAPDEVILA J; PROUGH RA METABOLIC ACTIVATION OF BENZO(A)PYRENE AND 9- HYDROXYBENZO(A)PYRENE BY LIVER MICROSOMAL FRACTIONS	26	6
6884	1	11095 1998 CANCER RESEARCH 58(5):921-926 Lubet RA; Gordon GB; Prough RA; Lei XD; You M; Wang Y; Grubbs CJ; Steele VE; Kelloff GJ; Thomas CF; Moon RD Modulation of methylnitrosourea-induced breast cancer in Sprague Dawley rats by dehydroepiandrosterone: Dose-dependent inhibition, effects of limited exposure, effects on peroxisomal enzymes, and lack of effects on levels of Ha-ras mutations	11	2
6885	5	6844 1990 ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 19(2):157-163 LUBET RA; GUENGERICH FP; NIMS RW THE INDUCTION OF ALKOXYRESORUFIN METABOLISM - A POTENTIAL INDICATOR OF ENVIRONMENTAL CONTAMINATION	42	7
6886	5	6723 1989 MUTATION RESEARCH 212(2):275-284 LUBET RA; MCKINNEY CE; CAMERON JW; GUENGERICH FP; NIMS RW PREFERENTIAL ACTIVATION OF 6-AMINOCHRYSENE AND 2- AMINOANTHRACENE TO MUTAGENIC MOIETIES BY DIFFERENT FORMS OF CYTOCHROME P450 IN HEPATIC 9000XG SUPERNATANTS FROM THE RAT	13	3
6887	9	10015 1996 BIOCHEMICAL PHARMACOLOGY 51(3):345-356 Luc PV; Adesnik M; Ganguly S; Shaw PM Transcriptional regulation of the CYP2B1 and CYP2BZ genes by C/EBP-related proteins	23	9
6888	10	6805 1990 ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 14(4):590-594 LUCAS D; BERTHOU F; DREANO Y; FLOCH HH; MENEZ JF ETHANOL-INDUCIBLE CYTOCHROME-P-450 - ASSESSMENT OF SUBSTRATES SPECIFIC CHEMICAL PROBES IN RAT-LIVER MICROSOMES	32	17
6889	15	8365 1993 ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 17(4):900-905 LUCAS D; BERTHOU F; DREANO Y; LOZACH P; VOLANT A; MENEZ JF COMPARISON OF LEVELS OF CYTOCHROMES-P-450, CYP1A2, CYP2E1, AND THEIR RELATED MONOOXYGENASE ACTIVITIES IN HUMAN SURGICAL LIVER SAMPLES	44	12
6890	14	11230 1998 FUNDAMENTAL & CLINICAL PHARMACOLOGY 12(5):553-558 Lucas D; Farez C; Bardou LG; Vaisse J; Attali JR; Valensi P Cytochrome P450 2E1 activity in diabetic and obese patients as assessed by chlorzoxazone hydroxylation	25	6
6891	12	9399 1995 ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 19(2):362-366 LUCAS D; MENEZ C; GIRRE C; BODENEZ P; HISPARD E; MENEZ JF DECREASE IN CYTOCHROME P4502E1 AS ASSESSED BY THE RATE OF CHLORZOXAZONE HYDROXYLATION IN ALCOHOLICS DURING THE WITHDRAWAL PHASE	41	5
6892	7	7826 1992 ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 16(5):916-921 LUCAS D; MENEZ JF; BERTHOU F; CAUVIN JM; DEITRICH RA DIFFERENCES IN HEPATIC-MICROSOMAL CYTOCHROME-P-450 ISOENZYME INDUCTION BY PYRAZOLE, CHRONIC ETHANOL, 3-METHYLCHOLANTHRENE, AND PHENOBARBITAL IN HIGH ALCOHOL SENSITIVITY (HAS) AND LOW ALCOHOL SENSITIVITY (LAS) RATS	6	1
6893	1	3656 1978 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 100(1):298-299 LUCCHESE RR; SCHAEFER HF METAL-CARBENE COMPLEXES AND POSSIBLE ROLE OF HYDROXY-CARBENE IN FORMALDEHYDE LASER PHOTOCHEMISTRY	51	0
6894	2	1587 1971 FEBS LETTERS 12(4):213-& LUCIANI S EFFECTS OF TANNIC ACID AND 2-THENOYLTRIFLUOROACETONE ON SUCCINATE OXIDATION AND PENETRATION ACROSS MITOCHONDRIAL MEMBRANE	8	0
6895	6	1969 1972 LIFE SCIENCES PT-2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY 11(12):597-& LUCIER GW; KLEIN R; MCDANIEL OS; MATTHEWS HB INCREASED DEGRADATION OF RAT-LIVER CO-BINDING PIGMENT BY METHYLMERCURY HYDROXIDE	16	5
6896	7	3221 1977 ACTA BIOLOGICA ET MEDICA GERMANICA 36(7-8):981-998 LUDWIG P; SCHEWE T; RAPOPORT S SLOW IRREVERSIBLE INHIBITION OF RESPIRATORY-CHAIN OF NON- PHOSPHORYLATING SUB-MITOCHONDRIAL PARTICLES BY FREE FATTY-ACIDS AND THEIR METHYL-ESTERS AND MONOGLYCERIDES	12	1
6897	7	4164 1980 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 212(2):211-216 LUI EMK; LUCIER GW NEONATAL FEMINIZATION OF HEPATIC MONO-OXYGENASE IN ADULT MALE- RATS - ALTERED SEXUAL DIMORPHIC RESPONSE TO CADMIUM	20	0
6898	6	6125 1988 BIOCHIMICA ET BIOPHYSICA ACTA 954(3):265-270 LUKAT GS; JABRO MN; RODGERS KR; GOFF HM ELECTRON-PARAMAGNETIC RESONANCE SPECTROSCOPY OF THYROID PEROXIDASE	8	1
6899	3	5814 1987 BIOCHEMISTRY 26(22):6927-6932 LUKAT GS; RODGERS KR; GOFF HM ELECTRON-PARAMAGNETIC RESONANCE SPECTROSCOPY OF LACTOPEROXIDASE COMPLEXES - CLARIFICATION OF HYPERFINE SPLITTING FOR THE NO ADDUCT OF LACTOPEROXIDASE	29	2
6900	10	5408 1985 INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY ():99-112 LUKE BT; LOEW GH A THEORETICAL INVESTIGATION OF THE 1ST STEP IN THE METABOLIC REDUCTION OF HALOGENATED METHANES BY CYTOCHROME-P-450	0	0

#	Cited nodes	Nodes / Authors	GCS	LCS
6901	3	1352 1970 JOURNAL OF BIOLOGICAL CHEMISTRY 245(12):3179-& LUMENG L; DAVIS EJ MECHANISM OF ETHANOL SUPPRESSION OF GLUCONEOGENESIS - INHIBITION OF PHOSPHOENOLPYRUVATE SYNTHESIS FROM GLUTAMATE AND ALPHA-KETOGLUTARATE	13	1
6902	3	11842 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(13):7238-7243 Lund EG; Guileyardo JM; Russell DW cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain	58	10
6903	2	13072 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(25):22980-22988 Lund EG; Xie CL; Kotti T; Turley SD; Dietschy JM; Russell DW Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover	0	0
6904	7	7126 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(6):3304-3312 LUND J; AHLGREN R; WU DH; KAGIMOTO M; SIMPSON ER; WATERMAN MR TRANSCRIPTIONAL REGULATION OF THE BOVINE CYP17 (P-45017-ALPHA) GENE - IDENTIFICATION OF 2 CAMP REGULATORY REGIONS LACKING THE CONSENSUS CAMP-RESPONSIVE ELEMENT (CRE)	128	34
6905	7	6240 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(31):16195-16201 LUND J; FAUCHER DJ; FORD SP; PORTER JC; WATERMAN MR; MASON JI DEVELOPMENTAL EXPRESSION OF BOVINE ADRENOCORTICAL STEROID HYDROXYLASES - REGULATION OF P-45017-ALPHA EXPRESSION LEADS TO EPISODIC FETAL CORTISOL PRODUCTION	51	18
6906	11	5388 1985 EUROPEAN JOURNAL OF BIOCHEMISTRY 147(2):297-305 LUND J; WOODLAND MP; DALTON H ELECTRON-TRANSFER REACTIONS IN THE SOLUBLE METHANE MONOOXYGENASE OF METHYLOCOCCUS-CAPSULATUS (BATH)	82	1
6907	13	12706 2002 BIOCHEMICAL JOURNAL 363():297-303 Lundell K Cloning and expression of two novel pig liver and kidney fatty acid hydroxylases [cytochrome P450 (CYP)4A24 and CYP4A25]	0	0
6908	17	12516 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(13):9606-9612 Lundell K; Hansson R; Wikvall K Cloning and expression of a pig liver taurochenodeoxycholic acid 6 alpha-hydroxylase (CYP4A21) - A novel member of the CYP4A subfamily	3	1
6909	2	575 1967 ACTA CHEMICA SCANDINAVICA 21(5):1385-& LUNDQUIS.CG; KIESSLIN.KH OXIDATION OF DL-ALPHA-GLYCEROPHOSPHATE AND BETA-HYDROXYBUTYRATE IN RED AND WHITE SKELETAL MUSCLE	4	0
6910	4	11678 1999 GENE 226(2):327-338 Lundqvist E; Johansson I; Ingelman-Sundberg M Genetic mechanisms for duplication and multiduplication of the human CYP2D6 gene and methods for detection of duplicated CYP2D6 genes	25	1
6911	6	5833 1987 BIOLOGICHESKIE MEMBRANY 4(9):913-922 LUNEVICH AY; KIRILLOV VA; KISSEL MA; STRIZHAKOVA EP; KISSELEV PA PROTEIN-LIPID INTERACTIONS - THE INFLUENCE OF CYTOCHROME-P-450 ON THERMOTROPIC PROPERTIES OF LIPOSOMES MADE OF DIMYRISTOYL PHOSPHATIDYLCHOLINE AND DIMYRISTOYLPHOSPHATIDYLGLYCEROL MIXTURE	1	0
6912	41	10983 1998 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 357(1):45-57 Luo G; Zeldin DC; Blaisdell JA; Hodgson E; Goldstein JA Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid	22	13
6913	1	453 1966 ANNALES MEDICINAE EXPERIMENTALIS ET BIOLOGIAE FENNIAE S 44():1-& LUOMANMA.K STUDIES ON METABOLISM OF CARBON MONOXIDE	10	0
6914	5	7381 1991 ARCHIVES OF TOXICOLOGY 65(8):661-665 LUOTAMO M; ELOVAARA E; RAUNIO H; PELKONEN O; RIIHIMAKI V; VAINIO H DISTRIBUTION AND EFFECTS ON CYTOCHROME P450 SYSTEM OF 2 HEXACHLOROBIPHENYL ISOMERS IN THE RAT	1	0
6915	19	11481 1999 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 368(1):181-192 Lupien S; Karp F; Wildung M; Croteau R Regiospecific cytochrome P450 limonene hydroxylases from mint (Mentha) species: cDNA isolation, characterization, and functional expression of (-)-4S-limonene-3-hydroxylase and (-)- 4S-limonene-6-hydroxylase	23	4
6916	1	11216 1998 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 50(4-6):501-506 Lupp A; Kerst S; Karge E; Quack G; Klinger W Investigation on possible antioxidative properties of the NMDA- receptor antagonists ketamine, memantine, and amantadine in comparison to nicanartine in vitro	2	0
6917	1	226 1963 CANADIAN JOURNAL OF BIOCHEMISTRY AND PHYSIOLOGY 41(10):2205-& LUSENA CV; DASS CMS PARTICLES IN DISRUPTED RAT LIVER MITOCHONDRIA	2	0
6918	9	7332 1991 ADVANCES IN ENZYME REGULATION 31():307-317 LUSSKA AE; JONES KW; ELFERINK CJ; WU L; SHEN ES; WEN LP; WHITLOCK JP 2, 3, 7, 8-TETRACHLORODIBENZO-P-DIOXIN INDUCES CYTOCHROME P450IA1 ENZYME-ACTIVITY BY ACTIVATING TRANSCRIPTION OF THE CORRESPONDING GENE	1	0
6919	8	5257 1985 ACTA PHARMACOLOGICA ET TOXICOLOGICA 56(1):69-74 LUTHMAN H; INGELMANSUNDBERG M CYTOCHROME-P-450-DEPENDENT FRAGMENTATION OF DNA IN RECONSTITUTED MEMBRANES	2	1
6920	1	5922 1987 JOURNAL OF EXPERIMENTAL ZOOLOGY 243(2):289-298 LUTTMER SJ; LONGO FJ RATES OF MALE PRONUCLEAR ENLARGEMENT IN SEA-URCHIN ZYGOTES	22	1
6921	6	4005 1980 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 93(3):776-781 LUUTHE V; CUMPS J; DUMONT P METYRAPONE-REDUCED CYTOCHROME-P-450 COMPLEX - A SPECIFIC METHOD FOR THE DETERMINATION OF THE PHENOBARBITAL INDUCIBLE FORM OF RAT HEPATIC-MICROSOMAL CYTOCHROME-P-450	48	21
6922	8	12585 2001 MOLECULAR PLANT-MICROBE INTERACTIONS 14(7):918-924 Luyten E; Swinnen E; Vlassak K; Verreth C; Dombrecht B; Vanderleyden J Analysis of a symbiosis-specific cytochrome P450 homolog in Rhizobium sp, BR816	1	0
6923	13	2362 1973 SUB-CELLULAR BIOCHEMISTRY 2(1):1-31 LUZIKOV VN STABILIZATION OF ENZYMATIC SYSTEMS OF INNER MITOCHONDRIAL- MEMBRANE AND RELATED PROBLEMS - POSSIBLE APPROACH TO PROBLEM OF REGULATION OF MITOCHONDRIAL FORMATION	26	4
6924	4	6120 1988 BIOCHEMISTRY-MOSCOW 53(10):1373-1382 LUZIKOV VN RELATIONSHIP BETWEEN THE STABILITY OF CELL ORGANELLES AND THEIR FUNCTIONAL-STATE	0	0
6925	4	1037 1969 BIOCHIMICA ET BIOPHYSICA ACTA 180(3):429-& LUZIKOV VN; RAKHIMOV MM; BEREZIN IV EFFECT OF SUBSTRATES ON RECONSTITUTION OF MITOCHONDRIAL RESPIRATORY CHAIN UNDER VARIOUS CONDITIONS	11	3
6926	7	1825 1972 BIOCHIMICA ET BIOPHYSICA ACTA 267(1):37-& LUZIKOV VN; ROMASHIN.LV STUDIES ON STABILIZATION OF OXIDATIVE-PHOSPHORYLATION SYSTEM .2. ELECTRON TRANSFER-DEPENDENT RESISTANCE OF SUCCINATE OXIDASE AND NADH OXIDASE SYSTEMS OF SUBMITOCHONDRIAL PARTICLES TO PROTEINASES AND COBRA VENOM PHOSPHOLIPASE	21	6
6927	2	1589 1971 FEBS LETTERS 13(5):261-& LUZIKOV VN; ROMASHIN.LV; VOZNAYA NM SITES OF COBRA VENOM PHOSPHOLIPASE ACTION ON RESPIRATORY SYSTEM OF SUBMITOCHONDRIAL PARTICLES	4	3
6928	10	1269 1970 BIOCHIMICA ET BIOPHYSICA ACTA 223(1):16-& LUZIKOV VN; SAKS VA; BEREZIN IV COMPARATIVE STUDY OF THERMAL DEGRADATION OF ELECTRON TRANSFER PARTICLES AND RECONSTITUTED RESPIRATORY CHAIN RELATION OF ELECTRON TRANSFER TO REACTIVATION OF SUBMITOCHONDRIAL PARTICLES	17	10
6929	8	1536 1971 BIOCHIMICA ET BIOPHYSICA ACTA 245(2):321-& LUZIKOV VN; ZUBATOV AS; RAININA EI; BAKEYEVA LE DEGRADATION AND RESTORATION OF MITOCHONDRIA UPON DEAERATION AND SUBSEQUENT AERATION OF AEROBICALLY GROWN SACCHAROMYCES- CEREVISIAE CELLS	45	6
6930	7	4106 1980 FEBS LETTERS 115(1):31-34 LYAKHOVICH VV; POLYAKOVA NE; POPOVA VI; EREMENKO SI; OLKIN SE; WEINER LM AFFINITY MODIFICATION OF CYTOCHROME-P450 BY IODINE-CONTAINING STABLE IMINOXYL RADICAL	8	6
6931	4	12542 2001 JOURNAL OF HELMINTHOLOGY 75(3):259-265 Lyddiard JRA; Whitfield PJ Inhibition of Site I mitochondrial electron transport by an extract of the seeds of Millettia thonningii: a potential mechanism for the plant's molluscicidal and schistosome larvicidal activity	1	1
6932	4	12879 2002 JOURNAL OF PARASITOLOGY 88(1):163-170 Lyddiard JRA; Whitfield PJ; Bartlett A Antischistosomal bioactivity of isoflavonoids from Millettia thonningii (Leguminosae)	0	0
6933	28	12710 2002 BIOCHEMICAL PHARMACOLOGY 64(10):1447-1460 Ma JX; Bradbury JA; King L; Maronpot R; Davis LS; Breyer MD; Zeldin DC Molecular cloning and characterization of mouse CYP2J6, an unstable cytochrome P450 isoform	0	0
6934	47	11719 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(25):17777-17788 Ma JX; Qu W; Scarborough PE; Tomer KB; Moomaw CR; Maronpot R; Davis LS; Breyer MD; Zeldin DC Molecular cloning, enzymatic characterization, developmental expression, and cellular localization of a mouse cytochrome p450 highly expressed in Kidney	20	13
6935	11	11237 1998 GENOMICS 49(1):152-155 Ma JX; Ramachandran S; Fiedorek FT; Zeldin DC Mapping of the CYP2J cytochrome P450 genes to human chromosome 1 and mouse chromosome 4	5	3
6936	3	12892 2002 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A 65(17):1247-1260 Ma JYC; Yang HM; Barger MW; Siegel PD; Zhong BZ; Kriech AJ; Castranova V Alteration of pulmonary cytochrome P-450 system: Effects of asphalt fume condensate exposure	1	0
6937	12	12668 2002 AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY 59(21):2061-2069 Ma MK; Woo MH; McLeod HL Genetic basis of drug metabolism	1	0
6938	14	12431 2001 CURRENT DRUG METABOLISM 2(2):149-164 Ma Q Induction of CYP1A1. The AhR/DRE paradigm: Transcription, receptor regulation, and expanding biological roles	17	4
6939	21	13022 2003 CHEMICAL RESEARCH IN TOXICOLOGY 16(3):249-260 Ma Q; Lu AYH Origins of individual variability in P4501A induction	0	0
6940	6	8914 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 310(2):332-340 MA RL; COHEN MB; BERENBAUM MR; SCHULER MA BLACK SWALLOWTAIL (PAPILIO POLYXENES) ALLELES ENCODE CYTOCHROME P450S THAT SELECTIVELY METABOLIZE LINEAR FURANOCOUMARINS	44	21
6941	6	8570 1993 CIRCULATION RESEARCH 72(1):126-136 MA YH; GEBREMEDHIN D; SCHWARTZMAN ML; FALCK JR; CLARK JE; MASTERS BS; HARDER DR; ROMAN RJ 20-HYDROXYEICOSATETRAENOIC ACID IS AN ENDOGENOUS VASOCONSTRICTOR OF CANINE RENAL ARCUATE ARTERIES	133	38
6942	3	12725 2002 BIOMEDICAL CHROMATOGRAPHY 16(3):199-202 Maboudou P; Matheiu D; Bachelet H; Wiart JF; Lhermitte M Detection of oxidative stress. Interest of GC-MS for malondialdehyde and formaldehyde monitoring	1	0
6943	8	10008 1996 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 226(1):51-58 Macdonald IDG; Smith GCM; Wolf CR; Smith WE Observation of structural variation and spin state conversion of cytochrome P450 CYP2B4 on binding of sterically different substrates	2	2
6944	1	5893 1987 EXPERIMENTAL AND MOLECULAR PATHOLOGY 46(1):64-77 MACDONALD JR; THAYER KJ; SMUCKLER EA ISOLATION AND MAINTENANCE OF MONOLAYER HEPATOCYTES FROM THE LIVERS OF TOXIN-TREATED RATS	4	0
6945	5	4398 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256(16):8287-8290 MACDONALD MJ HIGH CONTENT OF MITOCHONDRIAL GLYCEROL-3-PHOSPHATE DEHYDROGENASE IN PANCREATIC-ISLETS AND ITS INHIBITION BY DIAZOXIDE	139	16
6946	6	9944 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 326(1):79-84 MacDonald MJ; Brown LJ Calcium activation of mitochondrial glycerol phosphate dehydrogenase restudied	23	3
6947	7	11926 2000 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 384(1):143-153 MacDonald MJ; Marshall LK Mouse lacking NAD(+)-linked glycerol phosphate dehydrogenase has normal pancreatic beta cell function but abnormal metabolite pattern in skeletal muscle	5	1
6948	8	12571 2001 MOLECULAR AND CELLULAR BIOCHEMISTRY 220(1-2):117-125 MacDonald MJ; Marshall LK Survey of normal appearing mouse strain which lacks malic enzyme and NAD(+)-linked glycerol phosphate dehydrogenase: Normal pancreatic beta cell function, but abnormal metabolite pattern in skeletal muscle	4	0
6949	4	6972 1990 CANCER RESEARCH 50(22):7203-7205 MACDONALD MJ; WARNER TF; MERTZ RJ HIGH-ACTIVITY OF MITOCHONDRIAL GLYCEROL PHOSPHATE DEHYDROGENASE IN INSULINOMAS AND CARCINOID AND OTHER TUMORS OF THE AMINE PRECURSOR UPTAKE DECARBOXYLATION SYSTEM	13	5
6950	6	7543 1991 ENDOCRINE REVIEWS 12(4):372-401 MACDONALD PC; DOMBROSKI RA; CASEY ML RECURRENT SECRETION OF PROGESTERONE IN LARGE AMOUNTS - AN ENDOCRINE METABOLIC DISORDER UNIQUE TO YOUNG-WOMEN	31	2
6951	3	4509 1982 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 104(2):620-625 MACDONALD TL; BURKA LT; WRIGHT ST; GUENGERICH FP MECHANISMS OF HYDROXYLATION BY CYTOCHROME-P-450 - EXCHANGE OF IRON-OXYGEN INTERMEDIATES WITH WATER	39	9
6952	13	5176 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259(24):5433-5439 MACGEOCH C; MORGAN ET; HALPERT J; GUSTAFSSON JA PURIFICATION, CHARACTERIZATION, AND PITUITARY REGULATION OF THE SEX-SPECIFIC CYTOCHROME-P-450 15-BETA-HYDROXYLASE FROM LIVER- MICROSOMES OF UNTREATED FEMALE RATS	97	0
6953	10	8872 1993 VETERINARNI MEDICINA 38(12):739-750 MACHALA M CYTOCHROMES P450 - TOXICOLOGICAL SIGNIFICANCE OF LEVEL DETERMINATION	0	0
6954	8	11177 1998 DRUG METABOLISM AND DISPOSITION 26(10):970-976 Machinist JM; Mayer MD; Roberts EM; Surber BW; Rodrigues AD Identification of the human liver cytochrome P450 enzymes involved in the in vitro metabolism of a novel 5-lipoxygenase inhibitor	2	1
6955	15	9623 1995 DRUG METABOLISM AND DISPOSITION 23(10):1163-1174 MACHINIST JM; MAYER MD; SHET MS; FERRERO JL; RODRIGUES AD IDENTIFICATION OF THE HUMAN LIVER CYTOCHROME-P450 ENZYMES INVOLVED IN THE METABOLISM OF ZILEUTON (ABT-077) AND ITS N- DEHYDROXYLATED METABOLITE, ABBOTT-66193	17	8
6956	15	8370 1993 AMERICAN JOURNAL OF PHYSIOLOGY 265(4):G735-G741 MACICA C; BALAZY M; FALCK JR; MIOSKOWSKI C; CARROLL MA CHARACTERIZATION OF CYTOCHROME P-450-DEPENDENT ARACHIDONIC-ACID METABOLISM IN RABBIT INTESTINE	18	9
6957	8	10860 1997 PHARMACOGENETICS 7(4):255-269 Mackenzie PI; Owens IS; Burchell B; Bock KW; Bairoch A; Belanger A; FournelGigleux S; Green M; Hum DW; Iyanagi T; Lancet D; Louisot P; Magdalou J; Chowdhury JR; Ritter JK; Schachter H; Tephly TR; Tipton KF; Nebert DW The UDP glycosyltransferase gene superfamily: Recommended nomenclature update based on evolutionary divergence	277	16
6958	3	2433 1974 BIOCHEMICAL PHARMACOLOGY 23(10):1531-1543 MACKERER CR; HAETTING.JR; SAUNDERS RN; SMITH WR; HUTSELL TC EFFECTS OF SC-26096 [2-METHYL-3-OXO-2-AZABICYCLO(2.2.2.) OCTAN- 6-EXO-YL 5-(4-BIPHENYLYL)-3METHYL VALERATE], A NEW HYPOLIPIDEMIC AGENT, ON MITOCHONDRIAL RESPIRATION AND OXIDATIVE-PHOSPHORYLATION	0	0
6959	5	7418 1991 BIOCHEMICAL PHARMACOLOGY 42(3):475-483 MACKIE JE; BACK DW; HAMILTON JW; MARKS GS ELEVATION OF DELTA-AMINOLEVULINIC-ACID SYNTHASE AND CYTOCHROME- PB1-P450 MESSENGER-RNA LEVELS BY DIHYDROPYRIDINES, DIHYDROQUINOLINES, SYDNONES, AND N-ETHYLPROTOPORPHYRIN-IX	6	1
6960	2	184 1962 JOURNAL OF BIOLOGICAL CHEMISTRY 237(9):2968-& MACKLER B; DUNCAN HM; RAO NA; COLLIPP PJ; HUENNEKENS FM AN ELECTRON TRANSPORT PARTICLE FROM YEAST - PURIFICATION AND PROPERTIES	101	15
6961	1	1451 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 145(1):194-& MACKLER B; HAYNES B; TATTONI DS; TIPPIT DF; KELLEY VC STUDIES OF ADRENAL STEROID HYDROXYLATION .1. PURIFICATION OF MICROSOMAL 21-HYDROXYLASE SYSTEM	22	16
6962	13	10100 1996 CHEMICAL RESEARCH IN TOXICOLOGY 9(1):223-226 Mackman R; Guo ZY; Guengerich FP; OrtizdeMontellano PR Active site topology of human cytochrome P450 2E1	13	4
6963	14	9970 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 331(1):134-140 Mackman R; TschirretGuth RA; Smith G; Hayhurst GP; Ellis SW; Lennard RS; Tucker GT; Wolf CR; deMontellano PRO Active-site topologies of human CYP2D6 and its aspartate-301- >glutamate, asparagine, and glycine mutants	28	10
6964	3	639 1967 BIOCHIMICA ET BIOPHYSICA ACTA 131(1):59-& MACLENNA.DH; TZAGOLOF.A; MCCONNEL.DG PREPARATION OF MICROSOMAL ELECTRON-TRANSFER COMPLEXES	36	0
6965	7	6003 1987 XENOBIOTICA 17(9):1095-1102 MACLEOD JN; SORENSEN MP; SHAPIRO BH STRAIN INDEPENDENT ELEVATION OF HEPATIC MONOOXYGENASE ENZYMES IN FEMALE MICE	20	7
6966	2	6219 1988 JOURNAL OF BACTERIOLOGY 170(9):4330-4337 MACLEOD RA; WISSE GA; STEJSKAL FL SENSITIVITY OF SOME MARINE-BACTERIA, A MODERATE HALOPHILE, AND ESCHERICHIA-COLI TO UNCOUPLERS AT ALKALINE PH	8	0
6967	6	1961 1972 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 183(3):489-498 MACLEOD SM; RENTON KW; EADE NR DEVELOPMENT OF HEPATIC MICROSOMAL DRUG-OXIDIZING ENZYMES IN IMMATURE MALE AND FEMALE RATS	88	23
6968	4	2173 1973 CHEMICO-BIOLOGICAL INTERACTIONS 7(1):29-37 MACLEOD SM; RENTON KW; EADE NR POST-MORTEM CHARACTERISTICS OF HEPATIC MICROSOMAL DRUG OXIDIZING ENZYME-SYSTEM	10	4
6969	3	1721 1972 ANALYTICAL BIOCHEMISTRY 45(2):624-& MACNICOL PK ANALYSIS OF ADENINE-NUCLEOTIDES AND METABOLIC INTERMEDIATES IN MATURE AND SENESCENT LEAF TISSUE	10	2
6970	4	2342 1973 PLANT PHYSIOLOGY 51(4):798-801 MACNICOL PK METABOLIC REGULATION IN SENESCING TOBACCO LEAF .2. CHANGES IN GLYCOLYTIC METABOLITE LEVELS IN DETACHED LEAF	14	0
6971	2	8838 1993 RAPID COMMUNICATIONS IN MASS SPECTROMETRY 7(7):605-609 MACRAE PV; JONES BC; TODD JFJ INVESTIGATION OF THE METABOLISM OF FELODIPINE USING ONLINE LIQUID-CHROMATOGRAPHY UV DIODE-ARRAY DETECTION ATMOSPHERIC- PRESSURE CHEMICAL-IONIZATION MASS-SPECTROMETRY AS A DIAGNOSTIC- TOOL	6	0
6972	3	12133 2000 JOURNAL OF CHROMATOGRAPHY B 741(2):145-153 Madani S; Howald WN; Lawrence RF; Shen DD Analysis of hydroxylated and N-dealkylated metabolites of terfenadine in microsomal incubates by liquid chromatography- mass spectrometry	1	0
6973	3	4258 1981 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 210(2):666-677 MADDAIAH VT; CLEJAN S; PALEKAR AG; COLLIPP PJ HORMONES AND LIVER-MITOCHONDRIA - EFFECTS OF GROWTH-HORMONE AND THYROXINE ON RESPIRATION, FLUORESCENCE OF 1-ANILINO-8- NAPHTHALENE SULFONATE AND ENZYME-ACTIVITIES OF COMPLEX I AND II OF SUB-MITOCHONDRIAL PARTICLES	29	1
6974	10	3879 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(7):2419-2427 MADHAVA K; COSCIA CJ DETERGENT-SOLUBILIZED NADPH-CYTOCHROME C (P-450) REDUCTASE FROM THE HIGHER-PLANT, CATHARANTHUS-ROSEUS - PURIFICATION AND CHARACTERIZATION	0	0
6975	7	1185 1970 AMERICAN JOURNAL OF CLINICAL NUTRITION 23(5):566-& MADHAVAN TV; SCHAFFNE.F; POPPER H CATABOLIC AND ANABOLIC HEPATOTOXICITY AND NUTRITION	9	1
6976	6	3762 1979 BIOCHEMICAL JOURNAL 184(3):491-499 MADHOK TC; DELUCA HF CHARACTERISTICS OF THE RAT-LIVER MICROSOMAL-ENZYME SYSTEM CONVERTING CHOLECALCIFEROL INTO 25-HYDROXYCHOLECALCIFEROL - EVIDENCE FOR THE PARTICIPATION OF CYTOCHROME-P-450	74	4
6977	1	95 1960 CANADIAN JOURNAL OF BIOCHEMISTRY AND PHYSIOLOGY 38(5):481-492 MADSEN NB THE OXIDATION OF SUCCINATE IN EXTRACTS OF XANTHOMONAS-PHASEOLI	4	0
6978	4	5602 1986 BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 37(5):759-766 MADYASTHA KM; CHADHA A METABOLISM OF 1,8-CINEOLE IN RAT - ITS EFFECTS ON LIVER AND LUNG MICROSOMAL CYTOCHROME-P-450 SYSTEMS	11	1
6979	6	5999 1987 XENOBIOTICA 17(5):539-549 MADYASTHA KM; SRIVATSAN V METABOLISM OF BETA-MYRCENE INVIVO AND INVITRO - ITS EFFECTS ON RAT-LIVER MICROSOMAL-ENZYMES	12	0
6980	10	6188 1988 DRUG METABOLISM AND DISPOSITION 16(5):765-772 MADYASTHA KM; SRIVATSAN V STUDIES ON THE METABOLISM OF I-MENTHOL IN RATS	11	1
6981	4	10446 1996 XENOBIOTICA 26(8):793-802 Mae T; Hosoe K; Fujii K; Yamashita K; Yamane T; Hidaka T; Ohashi T In vitro metabolism of a rifamycin derivative by animal and human liver microsomes, whole blood and expressed human CYP3A isoform	7	3
6982	6	11433 1998 XENOBIOTICA 28(8):759-766 Mae T; Hosoe K; Yamamoto T; Hidaka T; Ohashi T; Kleeman JM; Adams PE Effect of a new rifamycin derivative, rifalazil, on liver microsomal enzyme induction in rat and dog	4	0
6983	6	9653 1995 EUROPEAN JOURNAL OF BIOCHEMISTRY 228(1):144-148 MAEDA Y; EGGERTSEN G; NYBERG B; SETOGUCHI T; OKUDA KI; EINARSSON K; BJORKHEM I IMMUNOCHEMICAL DETERMINATION OF HUMAN CHOLESTEROL 7-ALPHA- HYDROXYLASE	4	1
6984	11	10688 1997 ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 3(1):1-6 Maeda Y; Morita K; Tasaki T; Kazusaka A; Imaoka S; Funae Y; Fujita S Strain differences in age-associated change in testosterone 6 beta-hydroxylation in Wistar and Dark Agouti rats	8	0
6985	3	12737 2002 BUNSEKI KAGAKU 51(1):13-19 Maehana K; Tani H; Kamataki T; Kamidate T Affinity partitioning of histidine-tagged cytochrome b(5) and an oligopeptide in an aqueous micellar two-phase system containing a metal-chelating polymer	0	0
6986	1	21 1958 ACTA CHEMICA SCANDINAVICA 12(6):1259-1273 MAEHLY AC; AKESON A STABILIZATION OF AQUEOUS HEMIN SOLUTIONS	59	2
6987	1	881 1968 JOURNAL OF BIOLOGICAL CHEMISTRY 243(2):301-& MAENO H; FEIGELSO.P STUDIES ON INTERACTION OF CARBON MONOXIDE WITH TRYPTOPHAN OXYGENASE OF PSEUDOMONAS	27	3
6988	20	11360 1998 PHARMACOGENETICS 8(2):137-155 Maenpaa J; Hall SD; Ring BJ; Strom SC; Wrighton SA Human cytochrome P450 3A (CYP3A) mediated midazolam metabolism: the effect of assay conditions and regioselective stimulation by alpha-naphthoflavone, terfenadine and testosterone	47	17
6989	16	8977 1994 BIOCHEMICAL PHARMACOLOGY 48(7):1363-1369 MAENPAA J; JUVONEN R; RAUNIO H; RAUTIO A; PELKONEN O METABOLIC INTERACTIONS OF METHOXSALEN AND COUMARIN IN HUMANS AND MICE	30	7
6990	13	8740 1993 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 44(1):61-67 MAENPAA J; PELKONEN O; CRESTEIL T; RANE A THE ROLE OF CYTOCHROME-P450 3A (CYP3A) ISOFORM(S) IN OXIDATIVE- METABOLISM OF TESTOSTERONE AND BENZPHETAMINE IN HUMAN ADULT AND FETAL LIVER	31	16
6991	17	8455 1993 BIOCHEMICAL PHARMACOLOGY 45(4):899-907 MAENPAA J; RANE A; RAUNIO H; HONKAKOSKI P; PELKONEN O CYTOCHROME-P450 ISOFORMS IN HUMAN FETAL TISSUES RELATED TO PHENOBARBITAL-INDUCIBLE FORMS IN THE MOUSE	21	13
6992	17	8456 1993 BIOCHEMICAL PHARMACOLOGY 45(5):1035-1042 MAENPAA J; SIGUSCH H; RAUNIO H; SYNGELMA T; VUORELA P; VUORELA H; PELKONEN O DIFFERENTIAL INHIBITION OF COUMARIN 7-HYDROXYLASE ACTIVITY IN MOUSE AND HUMAN LIVER-MICROSOMES	58	20
6993	8	7422 1991 BIOCHEMICAL PHARMACOLOGY 42(6):1229-1235 MAENPAA J; SYNGELMA T; HONKAKOSKI P; LANG MA; PELKONEN O COMPARATIVE-STUDIES ON COUMARIN AND TESTOSTERONE-METABOLISM IN MOUSE AND HUMAN LIVERS - DIFFERENTIAL INHIBITIONS BY THE ANTI- P450COH ANTIBODY AND METYRAPONE	26	16
6994	6	4437 1981 PHARMACOLOGICAL RESEARCH COMMUNICATIONS 13(2):121-132 MAFFEI FR; CARINI M; BERTULETTI R; TOFANETTI O INVITRO METABOLISM OF BEZAFIBRATE BY RAT-LIVER	0	0
6995	12	4197 1980 PHARMACOLOGICAL RESEARCH COMMUNICATIONS 12(6):523-537 MAFFEIFACINO R; CARINI M THE INHIBITORY EFFECT OF PYRAZINAMIDE ON MICROSOMAL MONO- OXYGENASE ACTIVITIES IS RELATED TO THE BINDING TO REDUCED CYTOCHROME-P-450	0	0
6996	12	3931 1979 PHARMACOLOGICAL RESEARCH COMMUNICATIONS 11(5):433-445 MAFFEIFACINO R; LANZANI R INTERACTION OF A SERIES OF BETA-ADRENERGIC BLOCKING-DRUGS WITH RAT HEPATIC MICROSOMAL MONO-OXYGENASE	0	0
6997	4	1874 1972 ENDOCRINOLOGY 90(2):444-& MAGALHAE.MC; MAGALHAE.MM ULTRASTRUCTURAL ALTERATIONS PRODUCED IN RAT ADRENAL BY AMINOGLUTETHIMIDE - STEREOLOGIC AND CYTOCHEMICAL STUDY	30	0
6998	2	6513 1989 CANCER SURVEYS 8(2):207-239 MAGEE PN THE EXPERIMENTAL BASIS FOR THE ROLE OF NITROSO-COMPOUNDS IN HUMAN CANCER	72	1
6999	6	9688 1995 GENOME 38(5):845-849 MAGHSOUDLOU SS; HUGHES TR; HORNSBY PJ ANALYSIS OF THE DISTAL 5'-REGION OF THE HUMAN CYP17 GENE	2	0
7000	7	10762 1997 JOURNAL OF CHEMICAL CRYSTALLOGRAPHY 27(3):183-189 Mague JT; Foroozesh M; Hopkins NE; Gan LLS; Alworth WL Aryl acetylene inhibitors for cytochrome P450-based monooxygenase isozymes	5	0

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