#	Cited nodes	Nodes / Authors	GCS	LCS
5601	7	5368 1985 DRUG METABOLISM AND DISPOSITION 13(1):58-61 KEDDERIS GL; RICKERT DE LOSS OF RAT-LIVER MICROSOMAL CYTOCHROME-P-450 DURING METHIMAZOLE METABOLISM - ROLE OF FLAVIN-CONTAINING MONOOXYGENASE	40	5
5602	7	5469 1985 MOLECULAR PHARMACOLOGY 28(2):207-214 KEDDERIS GL; RICKERT DE CHARACTERIZATION OF THE OXIDATION OF AMINE METABOLITES OF NITROTOLUENES BY RAT HEPATIC MICROSOMES - N-HYDROXYLATION AND C-HYDROXYLATION	6	1
5603	17	7643 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(33):22515-22521 KEDZIE KM; BALFOUR CA; ESCOBAR GY; GRIMM SW; HE YA; PEPPERL DJ; REGAN JW; STEVENS JC; HALPERT JR MOLECULAR-BASIS FOR A FUNCTIONALLY UNIQUE CYTOCHROME-P450IIB1 VARIANT	89	47
5604	22	8511 1993 BIOCHIMICA ET BIOPHYSICA ACTA 1164(2):124-132 KEDZIE KM; GRIMM SW; CHEN F; HALPERT JR HYBRID ENZYMES FOR STRUCTURE-FUNCTION ANALYSIS OF CYTOCHROME-P- 450-2B11	13	8
5605	21	7373 1991 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 291(1):176-186 KEDZIE KM; PHILPOT RM; HALPERT JR FUNCTIONAL EXPRESSION OF MAMMALIAN CYTOCHROMES-P450IIB IN THE YEAST SACCHAROMYCES-CEREVISIAE	30	20
5606	4	9989 1996 ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY 33(3-4):283-301 Keeley LL; Park JH; Lu KH; Bradfield JY Neurohormone signal transduction for dual regulation of metabolism and gene expression in insects: Hypertrehalosemic hormone as a model	12	0
5607	39	8813 1993 PHARMACOLOGY & THERAPEUTICS 58(3):301-317 KEENEY DS; WATERMAN MR REGULATION OF STEROID HYDROXYLASE GENE-EXPRESSION - IMPORTANCE TO PHYSIOLOGY AND DISEASE	23	10
5608	1	6772 1989 TOXICOLOGY AND APPLIED PHARMACOLOGY 101(1):158-169 KEFALAS V; STACEY NH POTENTIATION OF CARBON TETRACHLORIDE-INDUCED LIPID-PEROXIDATION BY TRICHLOROETHYLENE IN ISOLATED RAT HEPATOCYTES - NO ROLE IN ENHANCED TOXICITY	17	1
5609	6	7789 1991 TOXICOLOGY AND APPLIED PHARMACOLOGY 109(1):171-179 KEFALAS V; STACEY NH POTENTIATING EFFECTS OF CHLORINATED HYDROCARBONS ON CARBON- TETRACHLORIDE TOXICITY IN ISOLATED RAT HEPATOCYTES AND PLASMA- MEMBRANES	11	0
5610	1	74 1959 PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES 150(939):149-191 KEILIN D THE LEEUWENHOEK LECTURE - THE PROBLEM OF ANABIOSIS OR LATENT LIFE - HISTORY AND CURRENT CONCEPT	162	1
5611	1	30 1958 BIOCHIMICA ET BIOPHYSICA ACTA 27(1):173-184 KEILIN D; HARTREE EF SPECTROPHOTOMETRIC STUDY OF SUSPENSIONS OF PIGMENTED PARTICLES	30	4
5612	2	4968 1983 MOLECULAR PHARMACOLOGY 23(3):735-742 KELLER GM; JEFCOATE CR MODULATION OF MICROSOMAL BENZO[A]PYRENE METABOLISM BY DNA	6	0
5613	3	9419 1995 APPLIED AND ENVIRONMENTAL MICROBIOLOGY 61(10):3628-3632 KELLER NP; SEGNER S; BHATNAGAR D; ADAMS TH STCS, A PUTATIVE P-450 MONOOXYGENASE, IS REQUIRED FOR THE CONVERSION OF VERSICOLORIN-A TO STERIGMATOCYSTIN IN ASPERGILLUS-NIDULANS	18	3
5614	4	5953 1987 MOLECULAR PHARMACOLOGY 32(2):206-211 KELLEY M; HANTELLE P; SAFE S; LEVIN W; THOMAS PE COINDUCTION OF CYTOCHROME-P-450 ISOZYMES IN RAT-LIVER BY 2,4,5,2',4',5'-HEXACHLOROBIPHENYL OR 3-METHOXY-4- AMINOAZOBENZENE	35	22
5615	6	6882 1990 BIOCHEMICAL PHARMACOLOGY 39(12):1991-1998 KELLEY M; WOMACK J; SAFE S EFFECTS OF CYTOCHROME-P-450 MONOOXYGENASE INDUCERS ON MOUSE HEPATIC-MICROSOMAL METABOLISM OF TESTOSTERONE AND ALKOXYRESORUFINS	22	11
5616	11	10638 1997 CURRENT OPINION IN BIOTECHNOLOGY 8(3):274-278 Kellner DG; Maves SA; Sligar SG Engineering cytochrome P450s for bioremediation	28	4
5617	3	10693 1997 EUROPEAN JOURNAL OF BIOCHEMISTRY 245(2):349-354 Kelly GP; Muskett FW; Whitford D Analysis of backbone dynamics in cytochrome b(5) using N-15-NMR relaxation measurements	11	0
5618	5	6104 1988 BIOCHEMICAL SOCIETY TRANSACTIONS 16(6):1086-1088 KELLY SL; KELLY DE ANALYSIS AND EXPLOITATION OF CYTOCHROME-P-450 IN YEAST	1	0
5619	5	5353 1985 CARCINOGENESIS 6(9):1321-1325 KELLY SL; KELLY DE; KING DJ; WISEMAN A INTERACTION BETWEEN YEAST CYTOCHROME-P-450 AND CHEMICAL CARCINOGENS	19	7
5620	4	10708 1997 FEBS LETTERS 412(1):233-235 Kelly SL; Lamb DC; Kelly DE Sterol 22-desaturase, cytochrome P45061, possesses activity in xenobiotic metabolism	9	2
5621	6	8294 1992 PESTICIDE SCIENCE 36(1):27-30 KELLY SL; TOPAL A; BARNETT I; KELLY DE; HENDRY GAF ROLE OF CYTOCHROME-P450 IN TULIP BULB PROBED BY SUBSTRATE- BINDING STUDIES	5	0
5622	20	11389 1998 PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 61 61():25-64 Kemper B Regulation of cytochrome P450 gene transcription by phenobarbital	6	2
5623	7	9237 1994 JOURNAL OF NEUROSCIENCE RESEARCH 39(5):576-588 KEMPERMANN G; KNOTH R; GEBICKEHAERTER PJ; STOLZ BJ; VOLK B CYTOCHROME-P450 IN RAT ASTROCYTES IN-VIVO AND IN-VITRO - INTRACELLULAR-LOCALIZATION AND INDUCTION BY PHENYTOIN	19	6
5624	24	9450 1995 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 321(2):277-288 KEMPF AC; ZANGER UM; MEYER UA TRUNCATED HUMAN P450 2D6 - EXPRESSION IN ESCHERICHIA-COLI, NI2+-CHELATE AFFINITY PURIFICATION, AND CHARACTERIZATION OF SOLUBILITY AND AGGREGATION	31	19
5625	6	10472 1997 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 41(3):654-660 Kempf DJ; Marsh KC; Kumar G; Rodrigues AD; Denissen JF; McDonald E; Kukulka MJ; Hsu A; Granneman GR; Baroldi PA; Sun E; Pizzuti D; Plattner JJ; Norbeck DW; Leonard JM Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir	130	5
5626	5	7030 1990 DRUG METABOLISM AND DISPOSITION 18(5):788-793 KENNA JG; MARTIN JL; SATOH H; POHL LR FACTORS AFFECTING THE EXPRESSION OF TRIFLUOROACETYLATED LIVER MICROSOMAL PROTEIN NEOANTIGENS IN RATS TREATED WITH HALOTHANE	60	6
5627	5	7141 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(20):11425-11428 KENNEDY CH; MASON RP A REEXAMINATION OF THE CYTOCHROME-P-450-CATALYZED FREE-RADICAL PRODUCTION FROM A DIHYDROPYRIDINE - EVIDENCE OF TRACE TRANSITION-METAL CATALYSIS	14	6
5628	5	4541 1982 BIOCHEMICAL PHARMACOLOGY 31(11):2011-2016 KENNEDY KA; SLIGAR SG; POLOMSKI L; SARTORELLI AC METABOLIC-ACTIVATION OF MITOMYCIN-C BY LIVER-MICROSOMES AND NUCLEI	82	6
5629	2	6660 1989 JOURNAL OF CLINICAL INVESTIGATION 83(4):1326-1335 KENNEDY TP; RAO NV; HOPKINS C; PENNINGTON L; TOLLEY E; HOIDAL JR ROLE OF REACTIVE OXYGEN SPECIES IN REPERFUSION INJURY OF THE RABBIT LUNG	158	3
5630	2	5842 1987 CANCER RESEARCH 47(16):4271-4277 KENSLER TW; EGNER PA; DOLAN PM; GROOPMAN JD; ROEBUCK BD MECHANISM OF PROTECTION AGAINST AFLATOXIN TUMORIGENICITY IN RATS FED 5-(2-PYRAZINYL)-4-METHYL-1,2-DITHIOL-3-THIONE (OLTIPRAZ) AND RELATED 1,2-DITHIOL-3-THIONES AND 1,2-DITHIOL-3- ONES	184	11
5631	3	7997 1992 CARCINOGENESIS 13(1):95-100 KENSLER TW; GROOPMAN JD; EATON DL; CURPHEY TJ; ROEBUCK BD POTENT INHIBITION OF AFLATOXIN-INDUCED HEPATIC TUMORIGENESIS BY THE MONOFUNCTIONAL ENZYME INDUCER 1,2-DITHIOLE-3-THIONE	60	3
5632	23	10615 1997 CHEMICAL RESEARCH IN TOXICOLOGY 10(5):600-608 Kent UM; Bend JR; Chamberlin BA; Gage DA; Hollenberg PF Mechanism-based inactivation of cytochrome P450 2B1 by N- benzyl-1-aminobenzotriazole	12	7
5633	31	10565 1997 BIOCHEMISTRY 36(39):11707-11716 Kent UM; Hanna IH; Szklarz GD; Vaz ADN; Halpert JR; Bend JR; Hollenberg PF Significance of glycine 478 in the metabolism of N-benzyl-1- aminobenzotriazole to reactive intermediates by cytochrome P450 2B1	15	9
5634	20	11112 1998 CHEMICAL RESEARCH IN TOXICOLOGY 11(10):1154-1161 Kent UM; Roberts ES; Chun J; Hodge K; Juncaj J; Hollenberg PF Inactivation of cytochrome P450 2E1 by tert-butylisothiocyanate	14	9
5635	15	12365 2001 BIOCHEMISTRY 40(24):7253-7261 Kent UM; Roberts-Kirchhoff ES; Moon N; Dunham WR; Hollenberg PF Spectral studies of tert-butyl isothiocyanate-inactivated P450 2E1	4	1
5636	14	11572 1999 CHEMICAL RESEARCH IN TOXICOLOGY 12(4):317-322 Kent UM; Yanev S; Hollenberg PF Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by n-propylxanthate	13	4
5637	17	11551 1999 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 48(5):716-727 Kenworthy KE; Bloomer JC; Clarke SE; Houston JB CYP3A4 drug interactions: correlation of 10 in vitro probe substrates	53	11
5638	5	5023 1984 ANALYTICAL CHEMISTRY 56(11):1849-1852 KEOUGH T; MIHELICH ED; EICKHOFF DJ DIFFERENTIATION OF MONOEPOXIDE ISOMERS OF POLY-UNSATURATED FATTY-ACIDS AND FATTY-ACID ESTERS BY LOW-ENERGY CHARGE-EXCHANGE MASS-SPECTROMETRY	12	3
5639	2	3758 1979 BIOCHEMICAL JOURNAL 181(2):427-433 KERBEY AL; RADCLIFFE PM; RANDLE PJ; SUGDEN PH REGULATION OF KINASE REACTIONS IN PIG-HEART PYRUVATE- DEHYDROGENASE COMPLEX	64	0
5640	3	2980 1976 BIOCHEMICAL JOURNAL 154(2):327-348 KERBEY AL; RANDLE PJ; COOPER RH; WHITEHOUSE S; PASK HT; DENTON RM REGULATION OF PYRUVATE-DEHYDROGENASE IN RAT-HEART - MECHANISM OF REGULATION OF PROPORTIONS OF DEPHOSPHORYLATED AND PHOSPHORYLATED ENZYME BY OXIDATION OF FATTY-ACIDS AND KETONE- BODIES AND OF EFFECTS OF DIABETES - ROLE OF COENZYME-A, ACETYL- COENZYME-A AND REDUCED AND OXIDIZED NICOTINAMIDE-ADENINE DINUCLEOTIDEB	303	2
5641	26	7928 1992 BIOCHEMICAL PHARMACOLOGY 44(9):1745-1756 KERLAN V; DREANO Y; BERCOVICI JP; BEAUNE PH; FLOCH HH; BERTHOU F NATURE OF CYTOCHROMES P450 INVOLVED IN THE 2-/4-HYDROXYLATIONS OF ESTRADIOL IN HUMAN LIVER-MICROSOMES	87	27
5642	11	10366 1996 NETHERLANDS JOURNAL OF MEDICINE 48(6):237-243 Kerremans ALM Cytochrome P450 isoenzymes - Importance for the internist	13	4
5643	2	5521 1986 ADVANCES IN MICROBIAL PHYSIOLOGY 27():1-72 KERRIDGE D MODE OF ACTION OF CLINICALLY IMPORTANT ANTIFUNGAL DRUGS	86	0
5644	5	8454 1993 BIOCHEMICAL PHARMACOLOGY 45(4):833-839 KERRY NL; SOMOGYI AA; MIKUS G; BOCHNER F PRIMARY AND SECONDARY OXIDATIVE-METABOLISM OF DEXTROMETHORPHAN - INVITRO STUDIES WITH FEMALE SPRAGUE-DAWLEY AND DARK AGOUTI RAT-LIVER MICROSOMES	24	5
5645	5	3367 1977 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 358(3):258-259 KERSCHER L; OESTERHELT D FERREDOXIN OF PLANT TYPE FROM HALOBACTERIA	0	0
5646	3	3086 1976 EUROPEAN JOURNAL OF BIOCHEMISTRY 71(1):101-107 KERSCHER L; OESTERHELT D; CAMMACK R; HALL DO NEW PLANT-TYPE FERREDOXIN FROM HALOBACTERIA	63	6
5647	7	8828 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(9):4047-4051 KERSTING U; KERSTING D; SPRING KR KETOCONAZOLE ACTIVATES CL- CONDUCTANCE AND BLOCKS CL- AND FLUID ABSORPTION BY CULTURED CYSTIC-FIBROSIS (CFPAC-1) CELLS	24	3
5648	31	9168 1994 ISOPENTENOIDS AND OTHER NATURAL PRODUCTS 562():163-201 KERWIN JL EVOLUTION OF STRUCTURE AND FUNCTION OF FATTY-ACIDS AND THEIR METABOLITES	3	0
5649	9	10942 1998 ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 22(2):501-504 Kessova IG; DeCarli LM; Lieber CS Inducibility of cytochromes P-4502E1 and P-4501A1 in the rat pancreas	9	2
5650	52	9742 1995 JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 15(6):387-398 KETTER TA; FLOCKHART DA; POST RM; DENICOFF K; PAZZAGLIA PJ; MARANGELL LB; GEORGE MS; CALLAHAN AM THE EMERGING ROLE OF CYTOCHROME-P450 3A IN PSYCHOPHARMACOLOGY	118	20
5651	6	7405 1991 BIOCHEMICAL PHARMACOLOGY 41(4):635-638 KETTERER B; MEYER DJ; LALOR E; JOHNSON P; GUENGERICH FP; DISTLERATH LM; REILLY PEB; KADLUBAR FF; FLAMMANG TJ; YAMAZOE Y; BEAUNE PH A COMPARISON OF LEVELS OF GLUTATHIONE TRANSFERASES, CYTOCHROMES-P450 AND ACETYLTRANSFERASES IN HUMAN LIVERS	13	3
5652	5	5015 1984 ADVANCES IN ENZYME REGULATION 23():291-307 KEYES SR; HEIMBROOK DC; FRACASSO PM; ROCKWELL S; SLIGAR SG; SARTORELLI AC CHEMOTHERAPEUTIC ATTACK OF HYPOXIC TUMOR-CELLS BY THE BIOREDUCTIVE ALKYLATING AGENT MITOMYCIN-C	0	0
5653	8	2137 1973 BIOCHIMICA ET BIOPHYSICA ACTA 305(3):557-569 KEYHANI E; STOREY BT ENERGY CONSERVATION CAPACITY AND MORPHOLOGICAL INTEGRITY OF MITOCHONDRIA IN HYPOTONICALLY TREATED RABBIT EPIDIDYMAL SPERMATOZOA	100	4
5654	1	256 1963 SCIENCE 142(359):399-& KHALIFAH RA; COGGINS CW; LEWIS LN NEW NATURAL GROWTH PROMOTING SUBSTANCE IN YOUNG CITRUS FRUIT	25	0
5655	6	3092 1976 FARMAKOLOGIYA I TOKSIKOLOGIYA 39(4):500-506 KHALILOV EM; BOLSHEV VN EFFECT OF IONIZING-RADIATION ON ACTIVITY OF ENDOPLASMATIC RETICULUM ENZYMES METABOLIZING MEDICINAL AGENTS	0	0
5656	13	8056 1992 DRUG METABOLISM AND DISPOSITION 20(5):620-624 KHAN IU; BICKERS DR; HAQQI TM; MUKHTAR H INDUCTION OF CYP1A1 MESSENGER-RNA IN RAT EPIDERMIS AND CULTURED HUMAN EPIDERMAL-KERATINOCYTES BY BENZ(A)ANTHRACENE AND BETA- NAPHTHOFLAVONE	12	5
5657	16	11909 2000 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 373(2):335-345 Khan KK; Halpert JR Structure-function analysis of human cytochrome P450 3A4 using 7-alkoxycoumarins as active-site probes	16	3
5658	15	10691 1997 EUROPEAN JOURNAL OF BIOCHEMISTRY 244(2):361-370 Khan KK; Mazumdar S; Modi S; Sutcliffe M; Roberts GCK; Mitra S Steady-state and picosecond-time-resolved fluorenscence studies on the recombinant heme domain of Bacillus megaterium cytochrome P-450	7	3
5659	66	4205 1980 PHARMACOLOGY & THERAPEUTICS 11(1):43-107 KHAN MAQ INDUCTION OF DRUG-METABOLIZING-ENZYMES BY INSECTICIDES AND OTHER XENOBIOTICS	16	2
5660	7	6514 1989 CARCINOGENESIS 10(2):269-272 KHAN S; CODNER M; PAYNE JF; RAHIMTULA AD EFFECT OF A PRUDHOE BAY CRUDE-OIL ON HEPATIC AND RENAL PEROXISOMAL BETA-OXIDATION AND MIXED-FUNCTION OXIDASE ACTIVITIES IN RATS	4	0
5661	6	5839 1987 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 65(12):2400-2408 KHAN S; MARTIN M; RAHIMTULA AD; PAYNE JF EFFECT OF A PRUDHOE BAY CRUDE-OIL ON HEPATIC AND PLACENTAL DRUG-METABOLISM IN RATS	5	2
5662	10	6558 1989 DRUG METABOLISM AND DISPOSITION 17(4):360-364 KHAN WA; KUHN C; MERK HF; PARK SS; GELBOIN HV; BICKERS DR; MUKHTAR H ISOZYME-SPECIFIC MONOCLONAL ANTIBODY-DIRECTED ASSESSMENT OF INDUCTION OF HEPATIC CYTOCHROME-P-450 BY CLOTRIMAZOLE	6	5
5663	4	6049 1988 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 150(1):10-17 KHANI SC; PORTER TD; COON MJ ISOLATION AND PARTIAL CHARACTERIZATION OF THE GENE FOR CYTOCHROME-P-450 3A (P-450ALC) AND A 2ND CLOSELY RELATED GENE	13	12
5664	7	6231 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(15):7170-7175 KHANI SC; PORTER TD; FUJITA VS; COON MJ ORGANIZATION AND DIFFERENTIAL EXPRESSION OF 2 HIGHLY SIMILAR GENES IN THE RABBIT ALCOHOL-INDUCIBLE CYTOCHROME-P-450 SUBFAMILY	59	29
5665	7	2991 1976 BIOCHEMICAL PHARMACOLOGY 25(3):329-335 KHANNA JM; KALANT H; YEE Y; CHUNG S; SIEMENS AJ EFFECT OF CHRONIC ETHANOL TREATMENT ON METABOLISM OF DRUGS INVITRO AND INVIVO	64	7
5666	4	2244 1973 FOOD AND COSMETICS TOXICOLOGY 11(1):11-17 KHANNA KL; CORNISH HH EFFECT OF DAILY INGESTION OF CAFFEINE ON MICROSOMAL ENZYMES OF RAT-LIVER	13	2
5667	9	7841 1992 ANESTHESIOLOGY 77(6):1208-1214 KHARASCH ED; HERRMANN S; LABROO R KETAMINE AS A PROBE FOR MEDETOMIDINE STEREOISOMER INHIBITION OF HUMAN LIVER MICROSOMAL DRUG-METABOLISM	9	0
5668	25	8375 1993 ANESTHESIA AND ANALGESIA 76(5):1033-1039 KHARASCH ED; THUMMEL KE HUMAN ALFENTANIL METABOLISM BY CYTOCHROME-P450-3A3/4 - AN EXPLANATION FOR THE INTERINDIVIDUAL VARIABILITY IN ALFENTANIL CLEARANCE	49	12
5669	15	8376 1993 ANESTHESIOLOGY 79(4):795-807 KHARASCH ED; THUMMEL KE IDENTIFICATION OF CYTOCHROME-P450 2E1 AS THE PREDOMINANT ENZYME CATALYZING HUMAN LIVER MICROSOMAL DEFLUORINATION OF SEVOFLURANE, ISOFLURANE, AND METHOXYFLURANE	140	19
5670	4	10674 1997 ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 36(2):118-122 Khatisashvili G; Gordeziani M; Kvesitadze G; Korte F Plant monooxygenases: Participation in xenobiotic oxidation	6	0
5671	3	11074 1998 BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 62(4):773-777 Khedara A; Goto T; Kayashita J; Kato N Hypercholesterolemic effect in rats of a dietary addition of the nitric oxide synthase inhibitor, L-N(omega)Nitroarginine, by less synthesis of bile acids	6	0
5672	1	4470 1981 VOPROSY ONKOLOGII 27(12):47-51 KHUDOLEI VV; BARTSH H; MALAVEILLE C METABOLIC-ACTIVATION AND MUTAGENICITY OF CARCINOGENIC N- NITRAMINES IN A LIQUID-INCUBATION SYSTEM	1	0
5673	1	6955 1990 BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE 109(6):724-727 KHUDOLEI VV; MIZGIREV IV; MAIOROVA IG ENZYMATIC IMPRINTING IN ADULT ANIMALS	0	0
5674	2	2525 1974 FARMAKOLOGIYA I TOKSIKOLOGIYA 37(2):176-183 KHUEN KT; MYULLER D; KLINGER V MECHANISM IF PROTECTIVE ACTION OF SULFONAMIDES IN CCL4-PRODUCED LIVER INJURIES - EFFECT OF SULFONAMIDES ON BIOTRANSFORMATION REACTION IN RAT-LIVER	0	0
5675	1	12768 2002 DIGESTION 66(2):79-88 Kiba T The role of the autonomic nervous system in liver regeneration and apoptosis - Recent developments	1	0
5676	5	1187 1970 AMERICAN JOURNAL OF PHYSIOLOGY 219(3):641-& KIDDER GW CYTOCHROME-C AS SITE OF ACTION OF THIOCYANATE IN FROG GASTRIC MUCOSA	14	0
5677	29	3889 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(17):8377-8385 KIDO T; ARAKAWA M; KIMURA T ADRENAL-CORTEX MITOCHONDRIAL CYTOCHROME-P-450 SPECIFIC TO CHOLESTEROL SIDE-CHAIN CLEAVAGE REACTION - SPECTRAL CHANGES INDUCED BY DETERGENTS, ALCOHOLS, AMINES, PHOSPHOLIPIDS, STEROID HYDROXYLASE INHIBITORS, AND STEROID SUBSTRATES, AND CONDITIONS FOR ADRENODOXIN BINDING TO THE CYTOCHROME	50	12
5678	23	3874 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(23):1806-1815 KIDO T; KIMURA T FORMATION OF BINARY AND TERNARY COMPLEXES OF CYTOCHROME-P- 450SCC WITH ADRENODOXIN AND ADRENODOXIN REDUCTASE ADRENODOXIN COMPLEX - IMPLICATION IN ACTH FUNCTION	71	0
5679	4	6778 1989 TOXICOLOGY LETTERS 48(3):265-273 KIEFER F; WIEBEL FJ V79 CHINESE-HAMSTER CELLS EXPRESS CYTOCHROME-P-450 ACTIVITY AFTER SIMULTANEOUS EXPOSURE TO POLYCYCLIC AROMATIC-HYDROCARBONS AND AMINOPHYLLINE	20	4
5680	8	561 1966 PHARMACOLOGICAL REVIEWS 18(3):1091-& KIESE M BIOCHEMICAL PRODUCTION OF FERRIHEMOGLOBIN-FORMING DERIVATIVES FROM AROMATIC AMINES AND MECHANISMS OF FERRIHEMOGLOBIN FORMATION	233	15
5681	4	5959 1987 NEUROENDOCRINOLOGY 46(1):1-9 KIESEL L; CATT KJ STIMULATION OF LUTEINIZING-HORMONE RELEASE AND CYCLIC- NUCLEOTIDE PRODUCTION BY ARACHIDONIC-ACID IN CULTURED PITUITARY GONADOTROPHS	21	0
5682	5	735 1968 ACTA PHARMACOLOGICA ET TOXICOLOGICA 26(3):245-& KIESSLIN.KH EFFECT OF ETHANOL ON RAT LIVER .6. A POSSIBLE CORRELATION BETWEEN ALPHA-GLYCEROPHOSPHATE OXIDASE ACTIVITY AND MITOCHONDRIAL SIZE IN MALE AND FEMALE RATS FED ETHANOL	26	0
5683	1	6403 1989 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 159(1):283-289 KIFFEL L; LOEPER J; HOMBERG JC; LEROUX JP A HUMAN CYTOCHROME-P-450 IS RECOGNIZED BY ANTI-LIVER KIDNEY MICROSOME ANTIBODIES IN AUTOIMMUNE CHRONIC HEPATITIS	17	7
5684	9	8248 1992 LABORATORY INVESTIGATION 67(5):535-539 KIKKAWA Y DIVERSE ROLE OF PULMONARY CYTOCHROME-P-450 MONOOXYGENASE	22	5
5685	6	7295 1990 TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 160(4):323-332 KIKUCHI H; SAGAMI I; FUJII H; OHMACHI T; WATANABE M COMPLEMENTARY-DNA SEQUENCE OF 3-METHYLCHOLANTHRENE-INDUCIBLE P- 450 FROM THE RAT LUNG	10	1
5686	16	11925 2000 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 383(2):225-232 Kikuta Y; Kasyu H; Kusunose E; Kusunose M Expression and catalytic activity of mouse leukotriene B-4 omega-hydroxylase, CYP4F14	6	4
5687	15	11160 1998 DNA AND CELL BIOLOGY 17(3):221-230 Kikuta Y; Kato M; Yamashita Y; Miyauchi Y; Tanaka K; Kamada N; Kusunose M Human leukotriene B-4 omega-hydroxylase (CYP4F3) gene: Molecular cloning and chromosomal localization	21	10
5688	14	8684 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(13):9376-9380 KIKUTA Y; KUSUNOSE E; ENDO K; YAMAMOTO S; SOGAWA K; FUJIIKURIYAMA Y; KUSUNOSE M A NOVEL FORM OF CYTOCHROME-P-450 FAMILY-4 IN HUMAN POLYMORPHONUCLEAR LEUKOCYTES - CDNA CLONING AND EXPRESSION OF LEUKOTRIENE-B4 OMEGA-HYDROXYLASE	68	32
5689	14	11486 1999 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 369(2):193-196 Kikuta Y; Kusunose E; Ito M; Kusunose M Purification and characterization of recombinant rat hepatic CYP4F1	19	8
5690	11	9137 1994 FEBS LETTERS 348(1):70-74 KIKUTA Y; KUSUNOSE E; KONDO T; YAMAMOTO S; KINOSHITA H; KUSUNOSE M CLONING AND EXPRESSION OF A NOVEL FORM OF LEUKOTRIENE B-4 OMEGA-HYDROXYLASE FROM HUMAN LIVER	45	23
5691	16	12112 2000 JOURNAL OF BIOCHEMISTRY 127(6):1047-1052 Kikuta Y; Kusunose E; Kusunose M Characterization of human liver leukotriene B-4 omega- hydroxylase P450 (CYP4F2)	9	5
5692	10	12355 2001 BIOCHEMICAL PHARMACOLOGY 62(2):249-254 Kikuta Y; Kusunose E; Kusunose M Expression and induction of cytochrome P450s in rabbit parotid glands	0	0
5693	39	12936 2002 PROSTAGLANDINS & OTHER LIPID MEDIATORS 68-9():345-362 Kikuta Y; Kusunose E; Kusunose M Prostaglandin and leukotriene omega-hydroxylases	2	0
5694	7	7112 1990 JOURNAL OF BIOCHEMISTRY 107(2):280-286 KIKUTA Y; KUSUNOSE E; OKUMOTO T; KUBOTA I; KUSUNOSE M PURIFICATION AND CHARACTERIZATION OF 2 FORMS OF CYTOCHROME-P- 450 WITH OMEGA-HYDROXYLASE ACTIVITIES TOWARD PROSTAGLANDIN-A AND FATTY-ACIDS FROM RABBIT LIVER-MICROSOMES	27	20
5695	12	10979 1998 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 355(2):201-205 Kikuta Y; Kusunose E; Sumimoto H; Mizukami Y; Takeshige K; Sakaki T; Yabusaki Y; Kusunose M Purification and characterization of recombinant human neutrophil leukotriene B-4 omega-hydroxylase (cytochrome p450 4F3)	16	7
5696	13	11599 1999 DNA AND CELL BIOLOGY 18(9):723-730 Kikuta Y; Miyauchi Y; Kusunose E; Kusunose M Expression and molecular cloning of human liver leukotriene B-4 omega-hydroxylase (CYP4F2) gene	17	7
5697	7	7634 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(27):17821-17825 KIKUTA Y; SOGAWA K; HANIU M; KINOSAKI M; KUSUNOSE E; NOJIMA Y; YAMAMOTO S; ICHIHARA K; KUSUNOSE M; FUJIIKURIYAMA Y A NOVEL SPECIES OF CYTOCHROME-P-450 (P-450IB) SPECIFIC FOR THE SMALL-INTESTINE OF RABBITS - CDNA CLONING AND ITS EXPRESSION IN COS CELLS	20	16
5698	5	7686 1991 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 38(6):677-686 KILLEEN AA; SANE KS; ORR HT MOLECULAR AND ENDOCRINE CHARACTERIZATION OF A MUTATION INVOLVING A RECOMBINATION BETWEEN THE STEROID 21-HYDROXYLASE FUNCTIONAL GENE AND PSEUDOGENE	10	1
5699	12	11004 1998 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 242(1):209-212 Kim BR; Kim DH Influence of glutathione on the catalytic activity of reconstituted cytochrome P450 3A4	5	3
5700	2	9872 1995 PROTOPLASMA 184(1-4):111-117 KIM C; CRANE FL; BECKER GW; MORRE DJ PURIFICATION OF NADH-CYTOCHROME B(5) REDUCTASE FROM RAT-LIVER PLASMA-MEMBRANES	6	0

#	Cited nodes	Nodes / Authors	GCS	LCS
5701	3	9093 1994 DRUG METABOLISM AND DISPOSITION 22(6):858-865 KIM C; MANNING RO; BROWN RP; BRUCKNER JV A COMPREHENSIVE EVALUATION OF THE VIAL EQUILIBRATION METHOD FOR QUANTIFICATION OF THE METABOLISM OF VOLATILE ORGANIC-CHEMICALS - TRICHLOROETHYLENE	0	0
5702	9	11235 1998 GENES & DEVELOPMENT 12(15):2381-2391 Kim GT; Tsukaya H; Uchimiya H The ROTUNDIFOLIA3 gene of Arabidopsis thaliana encodes a new member of the cytochrome P-450 family that is required for the regulated polar elongation of leaf cells	34	5
5703	18	12442 2001 DRUG METABOLISM AND DISPOSITION 29(3):353-360 Kim H; Putt DA; Zangar RC; Wolf CR; Guengerich FP; Edwards RJ; Hollenberg PF; Novak RF Differential induction of rat hepatic cytochromes P450 3A1, 3A2, 2B1, 2B2, and 2E1 in response to pyridine treatment	3	1
5704	8	9620 1995 DRUG METABOLISM AND DISPOSITION 23(8):818-824 KIM H; REDDY S; NOVAK RF 3-METHYLCHOLANTHRENE AND PYRIDINE EFFECTS ON CYP1A1 AND CYP1A2 EXPRESSION IN RAT RENAL TISSUE	14	3
5705	1	1535 1971 BIOCHIMICA ET BIOPHYSICA ACTA 245(1):230-& KIM HD; MOMMAERT.WF RECONSTITUTION OF RABBIT MYOSIN FROM FAST AND SLOW MUSCLE	30	1
5706	17	8736 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 267(2):927-936 KIM HS; PUTT D; REDDY S; HOLLENBERG PF; NOVAK RF ENHANCED EXPRESSION OF RAT HEPATIC CYP2B1/2B2 AND 2E1 BY PYRIDINE - DIFFERENTIAL INDUCTION KINETICS AND MOLECULAR-BASIS OF EXPRESSION	29	7
5707	4	4447 1981 PHYTOCHEMISTRY 20(10):2311-2314 KIM IS; KIM SU; ANDERSON JA MICROSOMAL AGROCLAVINE HYDROXYLASE OF CLAVICEPS SPECIES	13	1
5708	7	7442 1991 BIOCHEMISTRY 30(42):10287-10294 KIM J; KEMPER B DIFFERENCES IN DEOXYRIBONUCLEASE-I HYPERSENSITIVE SITES IN PHENOBARBITAL-INDUCIBLE AND CONSTITUTIVE RABBIT P450IIC GENES	10	5
5709	7	12201 2000 NUCLEIC ACIDS RESEARCH 28(5):1126-1132 Kim J; Rivera-Rivera I; Kemper B Tissue-specific chromatin structure of the phenobarbital- responsive unit and proximal promoter of CYP2B1/2 and modulation by phenobarbital	4	0
5710	1	11021 1998 BIOCHEMICAL ARCHIVES 14(4):211-219 Kim JH; Park MK; Lee JY; Okuda H; Kim S; Hwang WI Antioxidant and antitumor effects of Manda	0	0
5711	19	12713 2002 BIOCHEMISTRY 41(30):9438-9447 Kim JS; Ahn T; Yim SK; Yun CH Differential effect of copper (II) on the cytochrome P450 enzymes and NADPH-cytochrome P450 reductase: Inhibition of cytochrome P450-catalyzed reactions by copper (II) ion	0	0
5712	7	11712 1999 JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY 32(3):232-238 Kim KW; Kim HY; Park SS; Jeong HS; Park SH; Lee JY; Jeong JH; Moon YH Gender differences in activity and induction of hepatic microsomal cytochrome P-450 by 1-bromopropane in Sprague-Dawley rats	1	0
5713	1	10786 1997 JOURNAL OF NUTRITION 127(12):2293-2301 Kim MJ; Aiken JM; Havighurst T; Hollander J; Ripple MO; Weindruch R Adult-onset energy restriction of rhesus monkeys attenuates oxidative stress-induced cytokine expression by peripheral blood mononuclear cells	17	0
5714	4	8877 1993 XENOBIOTICA 23(3):217-225 KIM ND; YOO JK; WON SM; PARK SS; GELBOIN HV PHENYTOIN INDUCTION OF CYTOCHROME P4502B IN MICE - EFFECTS ON HEXOBARBITAL HYDROXYLASE-ACTIVITY	7	1
5715	3	9503 1995 BIOCHEMICAL PHARMACOLOGY 50(10):1593-1597 KIM SG EXPRESSION OF RAT MICROSOMAL EPOXIDE HYDROLASE DURING PREGNANCY	2	0
5716	9	6969 1990 CANCER RESEARCH 50(17):5333-5339 KIM SG; NOVAK RF ROLE OF P450IIE1 IN THE METABOLISM OF 3-HYDROXYPYRIDINE, A CONSTITUENT OF TOBACCO-SMOKE - REDOX CYCLING AND DNA STRAND SCISSION BY THE METABOLITE 2,5-DIHYDROXYPYRIDINE	15	2
5717	8	8864 1993 TOXICOLOGY AND APPLIED PHARMACOLOGY 120(2):257-265 KIM SG; NOVAK RF THE INDUCTION OF CYTOCHROME-P4502E1 BY NITROGEN-CONTAINING AND SULFUR-CONTAINING HETEROCYCLES - EXPRESSION AND MOLECULAR REGULATION	48	4
5718	8	7680 1991 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 259(1):470-477 KIM SG; PHILPOT RM; NOVAK RF PYRIDINE EFFECTS ON P450IIE1, IIB AND IVB EXPRESSION IN RABBIT LIVER - CHARACTERIZATION OF HIGH-AFFINITY AND LOW-AFFINITY PYRIDINE N-OXYGENASES	34	6
5719	5	7730 1991 MOLECULAR PHARMACOLOGY 40(1):52-57 KIM SG; REDDY SL; STATES JC; NOVAK RF PYRIDINE EFFECTS ON EXPRESSION AND MOLECULAR REGULATION OF THE CYTOCHROME-P450IA GENE SUBFAMILY	40	11
5720	4	8046 1992 DRUG AND CHEMICAL TOXICOLOGY 15(4):313-327 KIM SY; CHUNG JH; KANG KW; JOE CO; PARK KH RELATIONSHIP BETWEEN ACTIVITIES OF CYTOCHROME-P-450 MONOOXYGENASES IN HUMAN PLACENTAL MICROSOMES AND BINDING OF BENZO(A)PYRENE METABOLITES TO CALF THYMUS DNA	5	0
5721	5	971 1969 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 133(2):327-& KIMELBER.HK; NICHOLLS P KINETIC STUDIES ON INTERACTION OF TMPD WITH CYTOCHROME C AND CYTOCHROME C OXIDASE	35	0
5722	25	10083 1996 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 74(1):97-103 Kimmett SM; McNamee JP; Marks GS Chick embryo liver microsomal steroid hydroxylations: Induction by dexamethasone, phenobarbital, and glutethimide and inactivation following the in ovo administration of porphyrinogenic compounds	2	1
5723	20	9548 1995 BRITISH JOURNAL OF PHARMACOLOGY 114(4):832-836 KIMONEN T; JUVONEN RO; ALHAVA E; PASANEN M THE INHIBITION OF CYP ENZYMES IN MOUSE AND HUMAN LIVER BY PILOCARPINE	18	5
5724	4	5665 1986 INORGANIC CHEMISTRY 25(13):2242-2246 KIMURA E; KOIKE T; SHIMIZU Y; KODAMA M COMPLEXES OF THE HISTAMINE H-2-ANTAGONIST CIMETIDINE WITH DIVALENT AND MONO-VALENT COPPER IONS	44	1
5725	7	5496 1985 TOXICOLOGY AND APPLIED PHARMACOLOGY 78(2):300-309 KIMURA R; KAWAI M; KATO Y; SATO M; AIMOTO T; MURATA T ROLE OF 3,5-DICHLOROPHENYL METHYL SULFONE, A METABOLITE OF M- DICHLOROBENZENE, IN THE INDUCTION OF HEPATIC-MICROSOMAL DRUG- METABOLIZING-ENZYMES BY M-DICHLOROBENZENE IN RATS	10	0
5726	5	5001 1983 TOXICOLOGY AND APPLIED PHARMACOLOGY 67(3):338-345 KIMURA R; KAWAI M; SATO M; AIMOTO T; MURATA T INDUCTION OF HEPATIC-MICROSOMAL DRUG-METABOLIZING-ENZYMES BY SULFUR-CONTAINING METABOLITES OF CHLORINATED BENZENES IN RATS	20	1
5727	15	12212 2000 PHARMACOLOGY 61(3):147-153 Kimura S; Gonzalez F Applications of genetically manipulated mice in pharmacogenetics and pharmacogenomics	5	0
5728	8	6549 1989 DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY 8(7):503-516 KIMURA S; HANIOKA N; MATSUNAGA E; GONZALEZ FJ THE RAT CLOFIBRATE-INDUCIBLE CYP4A GENE SUBFAMILY .1. COMPLETE INTRON AND EXON SEQUENCE OF THE CYP4A1 AND CYP4A2 GENES, UNIQUE EXON ORGANIZATION, AND IDENTIFICATION OF A CONSERVED 19-BP UPSTREAM ELEMENT	91	50
5729	10	6550 1989 DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY 8(7):517-525 KIMURA S; HARDWICK JP; KOZAK CA; GONZALEZ FJ THE RAT CLOFIBRATE-INDUCIBLE CYP4A SUBFAMILY .2. CDNA SEQUENCE OF IVA3, MAPPING OF THE CYP4A LOCUS TO MOUSE CHROMOSOME-4, AND COORDINATE AND TISSUE-SPECIFIC REGULATION OF THE CYP4A GENES	115	63
5730	7	11564 1999 CARCINOGENESIS 20(9):1825-1830 Kimura S; Kawabe M; Ward JM; Morishima H; Kadlubar FF; Hammons GJ; Fernandez-Salguero P; Gonzalez FJ CYP1A2 is not the primary enzyme responsible for 4- aminobiphenyl-induced hepatocarcinogenesis in mice	14	4
5731	7	13068 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(6):3580-3589 Kimura S; Kawamura M; Iyanagi T Role of Thr(66) in porcine NADIR-cytochrome b(5) reductase in catalysis and control of the rate-limiting step in electron transfer	1	0
5732	13	6459 1989 BIOCHEMISTRY 28(9):3798-3803 KIMURA S; KOZAK CA; GONZALEZ FJ IDENTIFICATION OF A NOVEL P450 EXPRESSED IN RAT LUNG - CDNA CLONING AND SEQUENCE, CHROMOSOME MAPPING, AND INDUCTION BY 3- METHYLCHOLANTHRENE	64	41
5733	1	5961 1987 NUCLEIC ACIDS RESEARCH 15(23):10053-10054 KIMURA S; PASTEWKA J; GELBOIN HV; GONZALEZ FJ CDNA AND AMINO-ACID-SEQUENCES OF 2 MEMBERS OF THE HUMAN P450IIC GENE SUBFAMILY	75	46
5734	7	5887 1987 EMBO JOURNAL 6(7):1929-1933 KIMURA S; SMITH HH; HANKINSON O; NEBERT DW ANALYSIS OF 2 BENZO[A]PYRENE-RESISTANT MUTANTS OF THE MOUSE HEPATOMA HEPA-1 P1450 GENE VIA CDNA EXPRESSION IN YEAST	70	32
5735	3	6349 1989 AMERICAN JOURNAL OF HUMAN GENETICS 45(6):889-904 KIMURA S; UMENO M; SKODA RC; MEYER UA; GONZALEZ FJ THE HUMAN DEBRISOQUINE 4-HYDROXYLASE (CYP2D) LOCUS - SEQUENCE AND IDENTIFICATION OF THE POLYMORPHIC CYP2D6 GENE, A RELATED GENE, AND A PSEUDOGENE	233	63
5736	36	4426 1981 MOLECULAR AND CELLULAR BIOCHEMISTRY 36(2):105-122 KIMURA T ACTH STIMULATION ON CHOLESTEROL SIDE-CHAIN CLEAVAGE ACTIVITY OF ADRENOCORTICAL MITOCHONDRIA - TRANSFER OF THE STIMULUS FROM PLASMA-MEMBRANE TO MITOCHONDRIA	77	16
5737	3	1196 1970 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 137(2):357-& KIMURA T; HUANG JJ STUDIES ON ADRENAL STEROID HYDROXYLASES - OPTICAL ABSORPTION SPECTROSCOPY OF ADRENAL IRON-SULFUR PROTEIN (ADRENODOXIN) AND ITS APOPROTEIN	12	5
5738	9	2041 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):94-106 KIMURA T; NAKAMURA S; HUANG JJ; CHU JW; WANG HP; TSERNOGL.D ELECTRON-TRANSPORT SYSTEM FOR ADRENOCORTICAL MITOCHONDRIAL STEROID HYDROXYLATION REACTIONS - MECHANISM OF HYDROXYLATION REACTIONS AND PROPERTIES OF FLAVOPROTEIN-IRON-SULFUR PROTEIN COMPLEX	15	8
5739	3	873 1968 JOURNAL OF BIOCHEMISTRY 63(6):716-& KIMURA T; OHNO H PREPARATION OF TESTIS NON-HEME IRON PROTEIN AND SUBSTITUTION FOR ADRENODOXIN BY VARIOUS NON-HEME IRON PROTEINS IN STEROID 11-BETA-HYDROXYLATION	30	24
5740	1	5448 1985 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 232(1):269-274 KIMURA T; SATOH S INHIBITORY EFFECT OF QUINACRINE ON MYOCARDIAL REACTIVE HYPEREMIA IN THE DOG	12	0
5741	2	190 1962 METHODS IN ENZYMOLOGY 5():562-570 KIMURA T; SINGER TP CHOLINE DEHYDROGENASE FROM RAT LIVER	24	2
5742	3	92 1960 BIOCHIMICA ET BIOPHYSICA ACTA 44(2):284-297 KIMURA T; SINGER TP; LUSTY CJ STUDIES ON CHOLINE DEHYDROGENASE .3. ORGANIZATION OF THE RESPIRATORY CHAIN IN CHOLINE OXIDASE	23	8
5743	3	686 1967 JOURNAL OF BIOLOGICAL CHEMISTRY 242(3):485-& KIMURA T; SUZUKI K COMPONENTS OF ELECTRON TRANSPORT SYSTEM IN ADRENAL STEROID HYDROXYLASE - ISOLATION AND PROPERTIES OF NON-HEME IRON PROTEIN (ADRENODOXIN)	234	137
5744	3	1021 1969 BIOCHEMISTRY 8(10):4027-& KIMURA T; SUZUKI K; PADMANAB.R; SAMEJIMA T; TARUTANI O; UI N STUDIES ON STEROID HYDROXYLASE . MOLECULAR PROPERTIES OF ADRENAL IRON-SULFUR PROTEIN	33	12
5745	6	3052 1976 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 53(3):273-276 KIMURA T; WANG HP; DEALVARE L; HONN KV; CHAVIN W CYTOCHROME-P-450 AND ADRENODOXIN IN ADRENAL MITOCHONDRIAL FRACTIONS OF SEVERAL LOWER-VERTEBRATES	4	2
5746	2	8361 1993 ADVANCES IN SECOND MESSENGER AND PHOSPHOPROTEIN RESEARCH 27():1-23 KINCAID R CALMODULIN-DEPENDENT PROTEIN PHOSPHATASES FROM MICROORGANISMS TO MAN - A STUDY IN STRUCTURAL CONSERVATISM AND BIOLOGICAL DIVERSITY	48	0
5747	13	5254 1984 XENOBIOTICA 14(1-2):187-206 KING DJ; AZARI MR; WISEMAN A STUDIES ON THE PROPERTIES OF HIGHLY PURIFIED CYTOCHROME-P-448 AND ITS DEPENDENT ACTIVITY BENZO[A]PYRENE HYDROXYLASE, FROM SACCHAROMYCES-CEREVISIAE	35	9
5748	31	12905 2002 MOLECULAR PHARMACOLOGY 61(4):840-852 King LM; Ma JX; Srettabunjong S; Graves J; Bradbury JA; Li LP; Spiecker M; Liao JK; Mohrenweiser H; Zeldin DC Cloning of CYP2J2 gene and identification of functional polymorphisms	1	0
5749	14	446 1966 ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY 28():155-& KING TE RECONSTITUTION OF RESPIRATORY CHAIN	75	12
5750	9	4740 1983 ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY 54():267-366 KING TE CARDIAC CYTOCHROME-C1	12	0
5751	3	1110 1969 JOURNAL OF BIOLOGICAL CHEMISTRY 244(7):1890-& KING TE; BAYLEY PM; MACKLER B OPTICAL ROTATORY DISPERSION OF MITOCHONDRIAL REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE DEHYDROGENASE FROM CARDIAC TISSUE	1	0
5752	6	181 1962 JOURNAL OF BIOLOGICAL CHEMISTRY 237(5):1686-& KING TE; HOWARD RL PREPARATION AND SOME PROPERTIES OF A REDUCED DIPHOSPPHOPYRIDINE NUCLEOTIDE DEHYDROGENASE FROM SNAKE VENOM DIGEST OF A HEART MUSCLE PREPARATION	86	28
5753	5	318 1964 JOURNAL OF BIOLOGICAL CHEMISTRY 239(6):1989-& KING TE; NICKEL KS; JENSEN DR IRON COPPER CYTOCHROME + LIPID CONTENTS OF HEART MUSCLE PREPARATION + HEART MITOCHONDRIA	73	11
5754	4	8256 1992 MAMMALIAN GENOME 3():S136-S152 KINGSLEY DM MOUSE CHROMOSOME-9	7	0
5755	1	160 1962 BIOCHEMICAL JOURNAL 82(1):164-& KINI MM; COOPER JR BIOCHEMISTRY OF METHANOL POISONING .4. EFFECT OF METHANOL AND ITS METABOLITES ON RETINAL METABOLISM	30	0
5756	12	9794 1995 LABORATORY INVESTIGATION 73(1):3-19 KINNULA VL; CRAPO JD; RAIVIO KO BIOLOGY OF DISEASE - GENERATION AND DISPOSAL OF REACTIVE OXYGEN METABOLITES IN THE LUNG	65	1
5757	5	680 1967 JOURNAL OF BIOCHEMISTRY 61(1):26-& KINOSHIT.T; HORIE S STUDIES ON P-450 .3. ON ABOSRPTION SPECTRUM OF P-450 IN RABBIT LIVER MICROSOMES	33	0
5758	6	528 1966 JOURNAL OF BIOCHEMISTRY 60(4):391-& KINOSHIT.T; HORIE S; SHIMAZON.N; YOHRO T STUDIES ON P-450 .I. PREPARATION AND PROPERTIES OF A SUBMITOCHONDRIAL PARTICULATE FRACTION FROM BOVINE ADRENAL CORTEX	24	0
5759	2	12055 2000 ENDOCRINOLOGY 141(4):1317-1324 Kinuta K; Tanaka H; Moriwake T; Aya K; Kato S; Seino Y Vitamin D is an important factor in estrogen biosynthesis of both female and male gonads	18	0
5760	6	9051 1994 CHEMICAL REVIEWS 94(2):373-431 KIPLINGER JL; RICHMOND TG; OSTERBERG CE ACTIVATION OF CARBON FLUORINE BONDS BY METAL-COMPLEXES	200	0
5761	3	10279 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(11):4122-4128 Kiriakidou M; McAllister JM; Sugawara T; Strauss JF Expression of steroidogenic acute regulatory protein (StAR) in the human ovary	56	2
5762	7	8416 1993 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 307(2):253-258 KIRITA S; MATSUBARA T CDNA CLONING AND CHARACTERIZATION OF A NOVEL MEMBER OF STEROID- INDUCED CYTOCHROME-P450 3A IN RATS	46	32
5763	4	6206 1988 GENE 68(2):229-237 KIRSCH DR; LAI MH; OSULLIVAN J ISOLATION OF THE GENE FOR CYTOCHROME-P450L1A1 (LANOSTEROL 14- ALPHA-DEMETHYLASE) FROM CANDIDA-ALBICANS	47	13
5764	7	6552 1989 DOKLADY AKADEMII NAUK SSSR 309(3):729-732 KISELEV PA; GARDA G; FINCH CAE; STIER A; GURINOVICH NA; KHATYLEVA SI; AKHREM AA DYNAMICS OF THE PROTEIN PROTEIN-INTERACTION IN A MONOOXYGENASE ENZYMATIC SYSTEM RECONSTRUCTED IN LIPOSOMES OF DIFFERENT PHOSPHOLIPID-COMPOSITION	0	0
5765	11	6925 1990 BIOCHEMISTRY-MOSCOW 55(11):1535-1544 KISELEV PA; GARDA G; FINCH SAE; STIER A; KHATYLEVA SY; AKHREM AA REGULATION OF THE CATALYTIC ACTIVITY OF THE MONOOXYGENASE ENZYME-SYSTEM DEPENDING ON THE STRUCTURE OF THE SUBSTRATE AND PHOSPHOLIPID-COMPOSITION OF THE MODEL MEMBRANE	0	0
5766	2	3314 1977 BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE 83(6):832-834 KISELEVA VN; GILEV AP; PARINOV VY; SHATTS VD; GERMANE SK DEMETHYLATION OF METHINDIONE	0	0
5767	5	10373 1996 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 56(1):44-52 Kishimoto D; Kurihara N Effects of cytochrome P450 antibodies on the oxidative demethylation of methoxychlor catalyzed by rat liver microsomal cytochrome P450 isozymes: Isozyme specificity and alteration of enantiotopic selectivity	1	0
5768	3	9831 1995 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 51(1):12-19 KISHIMOTO D; OKU A; KURIHARA N ENANTIOTOPIC SELECTIVITY OF CYTOCHROME P450-CATALYZED OXIDATIVE DEMETHYLATION OF METHOXYCHLOR - ALTERATION OF SELECTIVITY DEPENDING ON ISOZYMES AND SUBSTRATE CONCENTRATIONS	9	1
5769	3	10953 1998 ANALYTICAL BIOCHEMISTRY 261(1):16-28 Kiss L; Bieniek E; Weissmann N; Schutte H; Sibelius U; Gunther A; Bier J; Mayer K; Henneking K; Padberg W; Grimm H; Seeger W; Grimminger F Simultaneous analysis of 4- and 5-series lipoxygenase and cytochrome P450 products from different biological sources by reversed-phase high-performance liquid chromatographic technique	11	1
5770	10	11898 2000 AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 161(6):1917-1923 Kiss L; Schutte H; Mayer K; Grimm H; Padberg W; Seeger W; Grimminger F Synthesis of arachidonic acid-derived lipoxygenase end cytochrome P450 products in the intact human lung vasculature	9	3
5771	11	12801 2002 EUROPEAN JOURNAL OF BIOCHEMISTRY 269(7):1799-1805 Kisselev P; Schwarz D; Platt KL; Schunck WH; Roots I Epoxidation of benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1 in reconstituted membranes	1	0
5772	7	11650 1999 EUROPEAN JOURNAL OF BIOCHEMISTRY 260(3):768-773 Kisselev P; Tuckey RC; Woods ST; Triantopoulos T; Schwarz D Enzymatic properties of vesicle-reconstituted human cytochrome P450SCC (CYP11A1) - Differences in functioning of the mitochondrial electron-transfer chain using human and bovine adrenodoxin and activation by cardiolipin	2	0
5773	2	731 1967 STEROIDS 10(5):567-& KITABCHI AE INHIBITION OF STEROID C-21 HYDROXYLASE BY ASCORBATE - ALTERATIONS OF MICROSOMAL LIPIDS IN BEEF ADRENAL CORTEX	35	4
5774	15	3377 1977 JAPANESE JOURNAL OF PHARMACOLOGY 27(5):601-608 KITADA M; CHIBA K; KAMATAKI T; KITAGAWA H INHIBITION BY CYANIDE OF DRUG OXIDATIONS IN RAT-LIVER MICROSOMES	22	13
5775	13	9097 1994 DRUG METABOLISM REVIEWS 26(1-2):305-323 KITADA M; KAMATAKI T CYTOCHROME-P450 IN HUMAN FETAL LIVER - SIGNIFICANCE AND FETAL- SPECIFIC EXPRESSION	28	10
5776	9	2477 1974 CHEMICAL & PHARMACEUTICAL BULLETIN 22(4):752-756 KITADA M; KAMATAKI T; KITAGAWA H EFFECTS OF LIPID PEROXIDATION ON MICROSOMAL ELECTRON-TRANSPORT SYSTEM AND RATE OF DRUG-METABOLISM IN RAT-LIVER	16	2
5777	15	3242 1977 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 178(1):151-157 KITADA M; KAMATAKI T; KITAGAWA H NADH-SYNERGISM OF NADPH-DEPENDENT O-DEALKYLATION OF TYPE-2 COMPOUNDS, PARA-ANISIDINE AND PARA-PHENETIDINE, IN RAT-LIVER MICROSOMES	10	9
5778	17	4012 1980 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 97(4):1527-1534 KITADA M; OMORI S; IGARASHI T; KANAKUBO Y; KITAGAWA H SEX DIFFERENCE IN N-DEMETHYLATION ACTIVITY OF ETHYLMORPHINE IN RAT-LIVER MICROSOMES	7	4
5779	11	5668 1986 JAPANESE JOURNAL OF PHARMACOLOGY 40(2):347-349 KITADA M; YAMAGUCHI N; RIKIHISA T; KANAKUBO Y; KITAGAWA H EFFECTS OF CYTOCHROME-B5 ON ANILINE HYDROXYLATION CATALYZED BY A RECONSTITUTED SYSTEM CONTAINING ACETONE OR 2,2'-BIPYRIDINE	2	1
5780	2	1853 1972 CHEMICAL & PHARMACEUTICAL BULLETIN 20(4):650-& KITAGAWA H; KITADA M; HORIE T STUDIES ON DRUG-METABOLISM .13. POSSIBLE ROLE OF LIVER MICROSOMAL CYTOCHROME-P-450 IN OXIDATIVE N-DEMETHYLATION OF PARA-SUBSTITUTED DIMETHYLANILINE, N-METHYL-N-ALKYLANILINE AND N-METHYL-N-ACYLANILINE DERIVATIVES	6	0
5781	10	4639 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(20):2075-2080 KITAGAWA T; SAKAMOTO H; SUGIYAMA T; YAMANO T FORMATION OF THE SEMI-QUINONE FORM IN THE ANAEROBIC REDUCTION OF ADRENODOXIN REDUCTASE BY NADPH - RESONANCE RAMAN, ELECTRON- PARAMAGNETIC-RES, AND OPTICAL SPECTROSCOPIC EVIDENCE	20	0
5782	4	2034 1973 AMERICAN JOURNAL OF SURGERY 126(3):379-382 KITAMURA O; OZAWA K; HONJO I ALTERATIONS OF LIVER METABOLISM ASSOCIATED WITH EXPERIMENTAL ACUTE PANCREATITIS	17	0
5783	12	7849 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 292(1):136-140 KITAMURA R; SATO K; SAWADA M; ITOH S; KITADA M; KOMORI M; KAMATAKI T STABLE EXPRESSION OF CYTOCHROME-P450IIIA7 CDNA IN HUMAN BREAST- CANCER CELL-LINE MCF-7 AND ITS APPLICATION TO CYTOTOXICITY TESTING	27	15
5784	5	11775 1999 LIFE SCIENCES 65(17):1747-1756 Kitamura T; Tanaka K; Morita K; Saito S; Kiba T; Numata K; Sekihara H Dehydroepiandrosterone (DHEA) facilitates liver regeneration after partial hepatectomy in rats	2	0
5785	8	11349 1998 NEW ENGLAND JOURNAL OF MEDICINE 338(10):653-661 Kitanaka S; Takeyama K; Murayama A; Sato T; Okumura K; Nogami M; Hasegawa Y; Niimi H; Yanagisawa J; Tanaka T; Kato S Inactivating mutations in the 25-hydroxyvitamin D-3 1 alpha- hydroxylase gene in patients with pseudovitamin D-deficiency rickets	79	5
5786	2	12205 2000 PATHOLOGY INTERNATIONAL 50(5):353-362 Kitano M Host genes controlling the susceptibility and resistance to squamous cell carcinoma of the tongue in a rat model	0	0
5787	13	9088 1994 DRUG METABOLISM AND DISPOSITION 22(4):607-615 KITAREEWAN S; WALZ FG GENETIC AND DEVELOPMENTAL DIVERSITY OF HEPATIC CYTOCHROMES-P450 - WARFARIN AND PROGESTERONE METABOLISM BY HEPATIC MICROSOMES FROM 4 INBRED STRAINS OF RAT	5	3
5788	20	12123 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(50):39734-39740 Kitazume T; Takaya N; Nakayama N; Shoun H Fusarium oxysporum fatty-acid subterminal hydroxylase (CYP505) is a membrane-bound eukaryotic: Counterpart of Bacillus megaterium cytochrome P450BM3	5	4
5789	20	12802 2002 EUROPEAN JOURNAL OF BIOCHEMISTRY 269(8):2075-2082 Kitazume T; Tanaka A; Takaya N; Nakamura A; Matsuyama S; Suzuki T; Shoun H Kinetic analysis of hydroxylation of saturated fatty acids by recombinant P450foxy produced by an Escherichia coli expression system	0	0
5790	8	10318 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 278(3):1018-1027 Kitteringham NR; Davis C; Howard N; Pirmohamed M; Park BK Interindividual and interspecies variation in hepatic microsomal epoxide hydrolase activity: Studies, with cis- stilbene oxide, carbamazepine 10,11-epoxide and naphthalene	21	0
5791	2	10815 1997 LEUKEMIA & LYMPHOMA 25(5-6):427-& Kizaki M; Ueno H; Matsushita H; Takayama N; Muto A; Awaya N; Ikeda Y Retinoid resistance in leukemic cells	11	0
5792	3	10074 1996 BLOOD 87(2):725-733 Kizaki M; Ueno H; Yamazoe Y; Shimada M; Takayama N; Muto A; Matsushita H; Nakajima H; Morikawa M; Koeffler HP; Ikeda Y Mechanisms of retinoid resistance in leukemic cells: Possible role of cytochrome P450 and P-glycoprotein	55	3
5793	13	7626 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(16):10632-10637 KIZAWA H; TOMURA D; ODA M; FUKAMIZU A; HOSHINO T; GOTOH O; YASUI T; SHOUN H NUCLEOTIDE-SEQUENCE OF THE UNIQUE NITRATE NITRITE-INDUCIBLE CYTOCHROME-P-450 CDNA FROM FUSARIUM-OXYSPORUM	66	27
5794	5	5483 1985 PHOTOCHEMISTRY AND PHOTOBIOLOGY 42(6):779-783 KJELLBOM P; LARSSON C; ASKERLUND P; SCHELIN C; WIDELL S CYTOCHROME-P-450-420 IN PLANT PLASMA-MEMBRANES - A POSSIBLE COMPONENT OF THE BLUE-LIGHT-REDUCIBLE FLAVOPROTEIN-CYTOCHROME COMPLEX	37	0
5795	10	10641 1997 DERMATOLOGIC SURGERY 23(12):1169-1174 Klein JA; Kassarjdian N Lidocaine toxicity with tumescent liposuction - A case report of probable drug interactions	19	0
5796	9	1255 1970 BIOCHEMISTRY 9(19):3653-& KLEIN KO; HARDING BW ELECTRON TRANSPORT REVERSAL AND STEROID 11BETA-HYDROXYLATION IN ADRENAL CORTICAL MITOCHONDRIA	8	5
5797	12	8681 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(10):7553-7561 KLEIN ML; FULCO AJ CRITICAL RESIDUES INVOLVED IN FMN BINDING AND CATALYTIC ACTIVITY IN CYTOCHROME-P450(BM-3)	25	15
5798	8	9009 1994 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1201(2):245-250 KLEIN ML; FULCO AJ THE INTERACTION OF CYTOCHROME-C AND THE HEME DOMAIN OF CYTOCHROME P-450(BM-3) WITH THE REDUCTASE DOMAIN OF CYTOCHROME P-450(BM-3)	7	7
5799	8	5535 1986 AQUATIC TOXICOLOGY 8(4):231-241 KLEINOW KM; HAASCH ML; LECH JJ THE EFFECT OF TRICAINE ANESTHESIA UPON INDUCTION OF SELECT P- 450 DEPENDENT MONOOXYGENASE ACTIVITIES IN RAINBOW-TROUT (SALMO- GAIRDNERI)	20	3
5800	7	7005 1990 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 96(2):259-270 KLEINOW KM; HAASCH ML; WILLIAMS DE; LECH JJ A COMPARISON OF HEPATIC-P450 INDUCTION IN RAT AND TROUT (ONCORHYNCHUS-MYKISS) - DELINEATION OF THE SITE OF RESISTANCE OF FISH TO PHENOBARBITAL-TYPE INDUCERS	44	12

#	Cited nodes	Nodes / Authors	GCS	LCS
5801	4	1131 1969 JOURNAL OF NEUROCHEMISTRY 16(12):1629-& KLEITKE B; WOLLENBE.A RECONSTRUCTION OF GLYCEROLPHOSPHATE CYCLE IN SUSPENSIONS OF RAT BRAIN MITOCHONDRIA	4	3
5802	15	9775 1995 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 274(3):1450-1455 KLEKOTKA PA; RICHARDSON TH; JOHNSON EF; HALPERT JR INACTIVATION OF ESCHERICHIA-COLI EXPRESSED RABBIT CYTOCHROME-P- 450 2C ENZYMES BY 17-BETA-SUBSTITUTED STEROIDS	1	1
5803	35	10067 1996 BIOLOGICAL CHEMISTRY 377(11):741-762 Kleman M; Gustafsson JA Interactions of procarcinogenic heterocyclic amines and indolocarbazoles with the dioxin receptor	6	0
5804	2	734 1968 ACTA ENTOMOLOGICA BOHEMOSLOVACA 65(1):1-& KLEPKE AK; MICHEJDA JW DIFFERENTIAL SPECTRA OF CYTOCHROMES IN DEVELOPMENT OF FLIGHT- MUSCLES IN ANTHERAEA PERNYI	0	0
5805	1	1124 1969 JOURNAL OF CELL BIOLOGY 43(2P1):207-& KLEVECZ RR TEMPORAL ORDER IN MAMMALIAN CELLS .I. PERIODIC SYNTHESIS OF LACTATE DEHYDROGENASE IN CELL CYCLE	56	5
5806	2	3190 1976 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 73(11):4012-4016 KLEVECZ RR QUANTIZED GENERATION TIME IN MAMMALIAN-CELLS AS AN EXPRESSION OF CELLULAR CLOCK	73	4
5807	5	5154 1984 INTERNATIONAL REVIEW OF CYTOLOGY-A SURVEY OF CELL BIOLOGY 86():97-128 KLEVECZ RR; KAUFFMAN SA; SHYMKO RM CELLULAR CLOCKS AND OSCILLATORS	22	1
5808	1	1173 1969 SCIENCE 166(3912):1536-& KLEVEZ RR TEMPORAL COORDINATION OF DNA REPLICATION WITH ENZYME SYNTHESIS IN DIPOLOID AND HETEROPLOID CELLS	57	0
5809	33	12792 2002 ENDOCRINE REVIEWS 23(5):687-702 Kliewer SA; Goodwin B; Willson TM The nuclear pregnane X receptor: A key regulator of xenobiotic metabolism	2	0
5810	6	12873 2002 JOURNAL OF LIPID RESEARCH 43(3):359-364 Kliewer SA; Willson TM Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor	9	1
5811	18	6941 1990 BIOCHIMICA ET BIOPHYSICA ACTA 1044(1):158-164 KLIMEK J CYTOCHROME-P-450 INVOLVEMENT IN THE NADPH-DEPENDENT LIPID- PEROXIDATION IN HUMAN PLACENTAL MITOCHONDRIA	8	1
5812	11	11228 1998 FREE RADICAL BIOLOGY AND MEDICINE 24(7-8):1168-1175 Klimek J; Wozniak M; Szymanska G; Zelewski L Inhibitory effect of free radicals derived from organic hydroperoxide on progesterone synthesis in human term placental mitochondria	10	0
5813	15	312 1964 ERGEBNISSE DER PHYSIOLOGIE BIOLOGISCHEN CHEMIE UND EXPERIMENTELLEN PHARMAKOLOGIE 55():131-189 KLINGENBERG M MUSKELMITOCHONDRIEN	38	3
5814	1	12982 2003 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 412(1):2-2 Klingenberg M The dragging emergence of the P450 cytochrome	0	0
5815	5	53 1959 BIOCHEMISCHE ZEITSCHRIFT 331(4):312-333 KLINGENBERG M; BUCHER T FLUGMUSKELMITOCHONDRIEN AUS LOCUSTA MIGRATORIA MIT ATMUNGSKONTROLLE - AUFBAU UND ZUSAMMENSETZUNG DER ATMUNGSKETTE	83	22
5816	22	77 1960 ANNUAL REVIEW OF BIOCHEMISTRY 29():669-708 KLINGENBERG M; BUCHER T BIOLOGICAL OXIDATIONS	131	17
5817	4	54 1959 BIOCHEMISCHE ZEITSCHRIFT 331(4):334-336 KLINGENBERG M; SLENCZKA W ATMUNGSAKTIVITAT VON MITOCHONDRIEN VERSCHIEDENER ORGANE MIT GLYCERIN-1-P IM VERGLEICH ZU SUBSTRATEN DES TRICARBONSAURECYCLUS	29	14
5818	2	1709 1971 ZEITSCHRIFT FUR VERSUCHSTIERKUNDE 13(6):308-& KLINGER W AMIDOPYRINE-N-DEMETHYLATION BY 9000 G-LIVERSUPERNATANT OF WISTAR-RATS (JENA) - DETERMINATION OF NORMAL VALUES	9	0
5819	3	2377 1974 ACTA BIOLOGICA ET MEDICA GERMANICA 33(2):181-186 KLINGER W OPTIMAL INCUBATION CONDITIONS FOR FIRST STEP OF AMIDOPYRINE-N- DEMETHYLATION BY 9000XG LIVER SUPERNATANT OF NEWBORN AND ADULT RATS	3	2
5820	43	4697 1982 PHARMACOLOGY & THERAPEUTICS 16(3):377-429 KLINGER W BIOTRANSFORMATION OF DRUGS AND OTHER XENOBIOTICS DURING POSTNATAL-DEVELOPMENT	58	3
5821	3	5550 1986 ARCHIVES OF TOXICOLOGY ():382-385 KLINGER W; FREYTAG A; SCHMITT W INFLUENCE OF AGE, HEXOBARBITAL, AND ANILINE ON NADPH NADH DEPENDENT HYDROGEN-PEROXIDE PRODUCTION IN RAT HEPATIC MICROSOMES	0	0
5822	4	12479 2001 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 26(1-2):31-35 Klinger W; Karge E; Demme U; Kretzschmar M Interactions of melatonin with the liver microsomal cytochrome P450 system of rats and humans in vitro and effects on the P450 system and the antioxidative status in rat liver after acute treatment	0	0
5823	4	12481 2001 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 52(6):513-522 Klinger W; Lupp A; Barth A; Karge E; Knels L; Kuhn U; Muller D; Schiller F; Demme U; Lindstrom-Seppa P; Hanninen O Cytochrome P450 (P450) isoforms expression, P450 concentration, monooxygenase activities, reactive oxygen species formation, lipid peroxidation, and glutathione content in wild catch carp and tench liver - influence of a two weeks exposure to phenobarbital	0	0
5824	5	12955 2002 TOXICOLOGY LETTERS 128(1-3):129-144 Klinger W; Lupp A; Karge E; Baumbach H; Eichhorn F; Feix A; Fuldner F; Gernhardt S; Knels L; Kost B; Mertens G; Werner F; Oettel M; Romer W; Schwarz S; Elger W; Schneider B Estradiol, testosterone,, dehydroepiandrosterone and androstenedione: novel derivatives and enantiomers. Interactions with rat liver microsomal cytochrome P450 and antioxidant/radical scavenger activities in vitro	2	0
5825	10	3078 1976 ENVIRONMENTAL HEALTH PERSPECTIVES 18(DEC):13-23 KLINGER W; MULLER D DEVELOPMENTAL ASPECTS OF XENOBIOTIC TRANSFORMATION	12	2
5826	5	1245 1970 BIOCHEMICAL PHARMACOLOGY 19(10):2677-& KLINGER W; NEUGEBAU.A; SPLINTER FK; CHEMNITI.KH EFFECT OF ESTROGEN ON OXIDATIVE BIOTRANSFORMATION REACTIONS IN RAT LIVER	9	4
5827	2	10700 1997 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 22(2):165-171 Klinger W; Oelschlager H; Karge E; Rothley D Interaction of chlormezanone with rat liver microsomes and its degradation	5	2
5828	3	11656 1999 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 24(1):63-68 Klinger W; Oelschlager H; Rothley D; Karge E; Seeling A Interaction of chlormezanone enantiomers with rat liver microsomes	1	0
5829	3	834 1968 DIGESTION 1(1):2-& KLION FM; SCHAFFNE.F ULTRASTRUCTURAL STUDIES IN ALCOHOLIC LIVER DISEASE	33	0
5830	3	1695 1971 PROTOPLASMA 72(2-3):109-& KLITZING LV METABOLITE-REGULATION OF AEROBIC CELL-SUSPENSION OF SACCHAROMYCES-CARLSBERGENSIS AFTER FEEDING WITH GLUCOSE .1. SHIFT FROM RESPIRATION TO AEROBIC FERMENTATION	4	2
5831	6	3202 1976 STUDIA BIOPHYSICA 55(3):211-216 KLITZING LV OSCILLATORY CONTROLLED GLYCOLYSIS IN YEAST-CELLS - EXTENDED MODEL OF GLYCOLYTIC REGULATION	0	0
5832	9	9105 1994 ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 13(9):1483-1496 KLOEPPERSAMS PJ; BENTON E EXPOSURE OF FISH TO BIOLOGICALLY TREATED BLEACHED-KRAFT EFFLUENT .2. INDUCTION OF HEPATIC CYTOCHROME-P4501A IN MOUNTAIN WHITEFISH (PROSOPIUM-WILLIAMSONI) AND OTHER SPECIES	25	1
5833	5	6367 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 268(2):525-535 KLOEPPERSAMS PJ; STEGEMAN JJ THE TEMPORAL RELATIONSHIPS BETWEEN P450E-PROTEIN CONTENT, CATALYTIC ACTIVITY, AND MESSENGER-RNA LEVELS IN THE TELEOST FUNDULUS-HETEROCLITUS FOLLOWING TREATMENT WITH BETA- NAPHTHOFLAVONE	77	35
5834	9	7883 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 299(1):38-46 KLOEPPERSAMS PJ; STEGEMAN JJ EFFECTS OF TEMPERATURE-ACCLIMATION ON THE EXPRESSION OF HEPATIC CYTOCHROME-P4501A MESSENGER-RNA AND PROTEIN IN THE FISH FUNDULUS-HETEROCLITUS	36	10
5835	5	12171 2000 LANGMUIR 16(7):3414-3421 Kloss AA; Lavrik N; Yeung C; Leckband D Effect of the microenvironment on the recognition of immobilized cytochromes by soluble redox proteins	5	0
5836	3	10019 1996 BIOCHEMICAL PHARMACOLOGY 51(7):919-929 Klotz LO; Muller J; Fausel M; Gebhardt R; Weser U Reactivity of lipophilic diSchiff-base coordinated copper in rat hepatocytes	1	0
5837	11	11208 1998 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 54(1):7-12 Klotz U; Ammon E Clinical and toxicological consequences of the inductive potential of ethanol	19	2
5838	1	8348 1992 TSITOLOGIYA 34(7):53-62 KLYUBIN IV THE EFFECT OF INHIBITORS OF GLUCOSE-UTILIZATION ON THE CHEMILUMINESCENCE AND FLUORESCENCE OF MURINE PERITONEAL- MACROPHAGES	0	0
5839	8	7770 1991 PROSTAGLANDINS 42(1):47-54 KNAPP HR; MILLER AJ; LAWSON JA URINARY-EXCRETION OF DIOLS DERIVED FROM EICOSAPENTAENOIC ACID DURING N-3 FATTY-ACID INGESTION BY MAN	7	2
5840	6	11912 2000 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 375(1):145-153 Kneer N; Lardy H Thyroid hormone and dehydroepiandrosterone permit gluconeogenic hormone responses in hepatocytes	1	0
5841	4	3877 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(23):2160-2168 KNEER NM; WAGNER MJ; LARDY HA REGULATION BY CALCIUM OF HORMONAL EFFECTS ON GLUCONEOGENESIS	108	0
5842	6	5715 1986 NEUROENDOCRINOLOGY 43(1):44-48 KNEPEL W; MEYEN G EFFECT OF VARIOUS BLOCKERS OF ARACHIDONIC-ACID METABOLISM ON RELEASE OF BETA-ENDORPHIN-LIKE AND ADRENOCORTICOTROPIN-LIKE IMMUNOREACTIVITY INDUCED BY PHOSPHOLIPASE-A2 FROM RAT ADENOHYPOPHYSIS INVITRO	25	0
5843	9	7986 1992 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 70(12):1610-1617 KNICKLE LC; BEND JR DOSE-DEPENDENT, MECHANISM-BASED INACTIVATION OF CYTOCHROME-P450 MONOOXYGENASES INVIVO BY 1-AMINOBENZOTRIAZOLE IN LIVER, LUNG, AND KIDNEY OF UNTREATED, PHENOBARBITAL-TREATED, AND BETA- NAPHTHOFLAVONE-TREATED GUINEA-PIGS	21	11
5844	24	9302 1994 MOLECULAR PHARMACOLOGY 45(6):1273-1280 KNICKLE LC; BEND JR BIOACTIVATION OF ARACHIDONIC-ACID BY THE CYTOCHROME-P450 MONOOXYGENASES OF GUINEA-PIG LUNG - THE ORTHOLOGUE OF CYTOCHROME-P450-2B4 IS SOLELY RESPONSIBLE FOR FORMATION OF EPOXYEICOSATRIENOIC ACIDS	39	20
5845	12	9251 1994 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 270(1):377-385 KNICKLE LC; PHILPOT RM; BEND JR N-ARALKYLATED DERIVATIVES OF 1-AMINOBENZOTRIAZOLE ARE POTENT ISOZYME-SELECTIVE AND LUNG-SELECTIVE MECHANISM-BASED INHIBITORS OF GUINEA-PIG CYTOCHROME-P-450 IN-VIVO	8	5
5846	38	8735 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 267(2):758-764 KNICKLE LC; WEBB CD; HOUSE AA; BEND JR MECHANISM-BASED INACTIVATION OF CYTOCHROME P450-1A1 BY N- ARALKYL-1-AMINOBENZOTRIAZOLES IN GUINEA-PIG KIDNEY IN-VIVO AND IN-VITRO - MINIMAL EFFECTS ON METABOLISM OF ARACHIDONIC-ACID BY RENAL P450-DEPENDENT MONOOXYGENASES	13	8
5847	8	5632 1986 DRUG AND CHEMICAL TOXICOLOGY 9(3-4):253-273 KNIGHT EV; CHIN BH; UENG TH; ALVARES AP DIFFERENCES IN THE INVIVO AND INVITRO EFFECTS OF THE CARBAMATE INSECTICIDE, CARBARYL ON RAT HEPATIC MONOOXYGENASES	3	0
5848	4	5736 1986 TOXICOLOGY 40(3):327-339 KNIGHTS KM; CASSIDY MR; DREW R BENOXAPROFEN INDUCED TOXICITY IN ISOLATED RAT HEPATOCYTES	5	0
5849	9	5789 1987 BIOCHEMICAL PHARMACOLOGY 36(6):897-906 KNIGHTS KM; GOURLAY GK; COUSINS MJ CHANGES IN RAT HEPATIC-MICROSOMAL MIXED-FUNCTION OXIDASE ACTIVITY FOLLOWING EXPOSURE TO HALOTHANE UNDER VARIOUS OXYGEN CONCENTRATIONS	7	1
5850	9	4372 1981 JOURNAL OF APPLIED PHYSIOLOGY 51(6):1635-1642 KNOBLAUCH A; SYBERT A; BRENNAN NJ; SYLVESTER JT; GURTNER GH EFFECT OF HYPOXIA AND CO ON A CYTOCHROME P-450-MEDIATED REACTION IN RABBIT LUNGS	13	4
5851	15	7585 1991 GASTROENTEROLOGY 101(6):1680-1691 KNODELL RG; BROWNE DG; GWOZDZ GP; BRIAN WR; GUENGERICH FP DIFFERENTIAL INHIBITION OF INDIVIDUAL HUMAN LIVER CYTOCHROMES- P-450 BY CIMETIDINE	100	20
5852	2	6258 1988 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 245(3):845-849 KNODELL RG; DUBEY RK; WILKINSON GR; GUENGERICH FP OXIDATIVE-METABOLISM OF HEXOBARBITAL IN HUMAN-LIVER - RELATIONSHIP TO POLYMORPHIC S-MEPHENYTOIN 4-HYDROXYLATION	71	33
5853	3	4621 1982 GASTROENTEROLOGY 82(1):84-88 KNODELL RG; HOLTZMAN JL; CRANKSHAW DL; STEELE NM; STANLEY LN DRUG-METABOLISM BY RAT AND HUMAN HEPATIC MICROSOMES IN RESPONSE TO INTERACTION WITH H2-RECEPTOR ANTAGONISTS	156	16
5854	4	2352 1973 RADIATION RESEARCH 53(1):65-76 KNOTT JCA; WILLS ED EFFECTS OF WHOLE-BODY IRRADIATION AND HORMONES ON DRUG- METABOLISM IN LIVER ENDOPLASMIC-RETICULUM	22	5
5855	3	2530 1974 FEBS LETTERS 49(1):78-83 KNOWLES CJ; CALCOTT PH; MACLEOD RA PERIPLASMIC CO-BINDING C-TYPE CYTOCHROME IN A MARINE BACTERIUM	24	0
5856	3	810 1968 BIOCHIMICA ET BIOPHYSICA ACTA 162(3):348-& KNOWLES CJ; REDFEARN ER EFFECT OF COMBINED-NITROGEN SOURCES ON SYNTHESIS AND FUNCTION OF ELECTRON TRANSPORT SYSTEM OF AZOTOBACTER VINELANDII	17	0
5857	14	11809 1999 ONCOLOGY RESEARCH 11(11-12):523-528 Knupfer H; Knupfer MM; Hotfilder M; Preiss R P450-expression in brain tumors	2	0
5858	5	2451 1974 BIOCHEMISTRY 13(7):1543-1548 KNUTSON JC; DELUCA HF "25-HYDROXYVITAMIN-D3-24-HYDROXYLASE SUBCELLULAR LOCATION AND PROPERTIES	156	6
5859	11	11617 1999 DRUG METABOLISM AND DISPOSITION 27(12):1429-1433 Kobayashi K; Abe S; Nakajima M; Shimada N; Tani M; Chiba K; Yamamoto T Role of human CYP2B6 in S-mephobarbital N-demethylation	9	3
5860	7	5913 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262(12):5445-5447 KOBAYASHI K; AMANO M; KANBARA Y; HAYASHI K ONE-ELECTRON REDUCTION OF THE OXYFORM OF 2,4- DIACETYLDEUTEROCYTOCHROME P-450CAM	15	4
5861	12	12007 2000 CLINICAL CANCER RESEARCH 6(8):3297-3303 Kobayashi K; Mimura N; Fujii H; Minami H; Sasaki Y; Shimada N; Chiba K Role of human cytochrome p450 3A4 in metabolism of medroxyprogesterone acetate	7	5
5862	10	9516 1995 BIOCHEMISTRY 34(40):12932-12936 KOBAYASHI K; MIURA S; MIKI M; ICHIKAWA Y; TAGAWA S INTERACTION OF NADPH-ADRENODOXIN REDUCTASE WITH NADP(+) AS STUDIED BY PULSE-RADIOLYSIS	6	3
5863	6	11082 1998 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 45(4):361-368 Kobayashi K; Nakajima M; Chiba K; Yamamoto T; Tani M; Ishizaki T; Kuroiwa Y Inhibitory effects of antiarrhythmic drugs on phenacetin O- deethylation catalysed by human CYP1A2	18	8
5864	7	11611 1999 DRUG METABOLISM AND DISPOSITION 27(8):860-865 Kobayashi K; Nakajima M; Oshima K; Shimada N; Yokoi T; Chiba K Involvement of CYP2E1 as a low-affinity enzyme in phenacetin O- deethylation in human liver microsomes	10	3
5865	18	12708 2002 BIOCHEMICAL PHARMACOLOGY 63(5):889-896 Kobayashi K; Urashima K; Shimada N; Chiba K Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat	7	1
5866	9	13042 2003 DRUG METABOLISM AND DISPOSITION 31(7):833-836 Kobayashi K; Urashima K; Shimada N; Chiba K Selectivities of human cytochrome P450 inhibitors toward rat P450 isoforms: Study with cDNA-expressed systems of the rat	0	0
5867	7	11706 1999 JOURNAL OF BIOCHEMISTRY 125(6):1094-1103 Kobayashi M; Sakuradani E; Shimizu S Genetic analysis of cytochrome b(5) from arachidonic acid- producing fungus, Mortierella alpina 1S-4: Cloning, RNA editing and expression of the gene in Escherichia coli, and purification and characterization of the gene product	8	0
5868	10	10224 1996 JAPANESE JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 42(6):468-478 Kobayashi Y; Yamamoto T; Okui E; Kotani E; Yoshida T; Kuroiwa Y Regio-related differential induction of hepatic microsomal heme oxygenase and cytochrome P450 by substituted imidazole and pyridine compounds in rats	5	0
5869	13	9007 1994 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1200(1):11-18 KOBAYASHI Y; YOSHIDA T; KOTANI E; AOYAGI T; KUROIWA Y; TOBINAGA S INVOLVEMENT OF TESTOSTERONE IN THE INDUCTION OF HEPATIC- MICROSOMAL CYTOCHROME-P-450 2B1/2 (P-450 2B1/2) BY 1- BENZYLIMIDAZOLE IN MALE AND FEMALE RATS - SEX-DIFFERENTIATED INDUCTION OF P-450 2B1/2 SPECIES	7	2
5870	11	9905 1995 XENOBIOTICA 25(8):779-789 KOBAYASHI Y; YOSHIDA T; KOTANI E; MATSUURA Y; EGAWA H; AOYAGI T; IMAOKA S; FUNAE Y; TOBINAGA S; KUROIWA Y INDUCTION OF HEPATIC-MICROSOMAL P450 BY 4-PHENYLALKYLPYRIDINES IN RAT - CHAIN LENGTH-DEPENDENT AND SEX-RELATED DIFFERENTIAL INDUCTION OF P450S	6	1
5871	11	8774 1993 MOLECULAR CARCINOGENESIS 7(4):276-280 KOBLIAKOV V; KULIKOVA L; SAMOILOV D; LANG MA HIGH EXPRESSION OF CYTOCHROME-P450 2A-5 (COUMARIN 7- HYDROXYLASE) IN MOUSE HEPATOMAS	15	6
5872	22	7555 1991 EUROPEAN JOURNAL OF BIOCHEMISTRY 195(3):585-591 KOBLIAKOV V; POPOVA N; ROSSI L REGULATION OF THE EXPRESSION OF THE SEX-SPECIFIC ISOFORMS OF CYTOCHROME-P-450 IN RAT-LIVER	41	11
5873	22	13010 2003 BIOLOGICHESKIE MEMBRANY 20(3):265-272 Kobliakov VA Cytochrome P-450: Functions and regulation	0	0
5874	16	11058 1998 BIOCHEMISTRY-MOSCOW 63(8):885-898 Koblyakov VA Inducers of the cytochrome P-450 superfamily as promoters of carcinogenesis	4	2
5875	11	7244 1990 MOLECULAR PHARMACOLOGY 38(4):440-444 KOCAREK TA; SCHUETZ EG; GUZELIAN PS DIFFERENTIATED INDUCTION OF CYTOCHROME-P450B/E AND CYTOCHROME- P450P MESSENGER-RNAS BY DOSE OF PHENOBARBITAL IN PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES	64	22
5876	14	7732 1991 MOLECULAR PHARMACOLOGY 40(2):203-210 KOCAREK TA; SCHUETZ EG; GUZELIAN PS SELECTIVE INDUCTION OF CYTOCHROME-P450E BY KEPONE (CHLORDECONE) IN PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES	22	8
5877	9	8653 1993 IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 29A(1):62-66 KOCAREK TA; SCHUETZ EG; GUZELIAN PS TRANSIENT INDUCTION OF CYTOCHROME-P450-1A1 MESSENGER-RNA BY CULTURE-MEDIUM COMPONENT IN PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES	24	0
5878	10	8865 1993 TOXICOLOGY AND APPLIED PHARMACOLOGY 120(2):298-307 KOCAREK TA; SCHUETZ EG; GUZELIAN PS REGULATION OF PHENOBARBITAL-INDUCIBLE CYTOCHROME-P450 2B1/2 MESSENGER-RNA BY LOVASTATIN AND OXYSTEROLS IN PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES	25	3
5879	6	9380 1994 TOXICOLOGY LETTERS 71(2):183-196 KOCAREK TA; SCHUETZ EG; GUZELIAN PS REGULATION OF CYTOCHROME-P450-2B1/2 MESSENGER-RNAS BY KEPONE(R) (CHLORDECONE) AND POTENT ESTROGENS IN PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES ON MATRIGEL	6	1
5880	25	9461 1995 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 323(1):177-186 KOCH BM; SIBBESEN O; HALKIER BA; SVENDSEN I; MOLLER BL THE PRIMARY SEQUENCE OF CYTOCHROME P450TYR, THE MULTIFUNCTIONAL N-HYDROXYLASE CATALYZING THE CONVERSION OF L-TYROSINE TO P- HYDROXYPHENYLACETALDEHYDE OXIME IN THE BIOSYNTHESIS OF THE CYANOGENIC GLUCOSIDE DHURRIN IN SORGHUM-BICOLOR (L) MOENCH	43	16
5881	3	1329 1970 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 18(6):1073-& KOCH DE; MERKEL RA; PURCHAS BJ EFFECT OF POSTMORTEM MYOTOMY ON GLYCOLYSIS AND ULTIMATE QUALITATIVE CHARACTERISTICS OF PORCINE LONGISSIMUS MUSCLES	3	0
5882	8	6456 1989 BIOCHEMISTRY 28(8):3145-3152 KOCH JA; WAXMAN DJ POSTTRANSLATIONAL MODIFICATION OF HEPATIC CYTOCHROME-P-450 - PHOSPHORYLATION OF PHENOBARBITAL-INDUCIBLE P-450 FORMS PB-4 (IIB1) AND PB-5 (IIB2) IN ISOLATED RAT HEPATOCYTES AND INVIVO	30	13
5883	3	4425 1981 KHIMIKO-FARMATSEVTICHESKII ZHURNAL 15(1):64-68 KOCHERGINSKY NM ANALYSIS OF STRUCTURE-ACTIVITY-RELATIONSHIPS OF MEMBRANE-ACTIVE CHEMICAL-COMPOUNDS	0	0
5884	4	7854 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 293(1):187-194 KOCHS G; WERCKREICHHART D; GRISEBACH H FURTHER CHARACTERIZATION OF CYTOCHROME-P450 INVOLVED IN PHYTOALEXIN SYNTHESIS IN SOYBEAN - CYTOCHROME-P450 CINNAMATE 4- HYDROXYLASE AND 3,9-DIHYDROXYPTEROCARPAN 6A-HYDROXYLASE	22	5
5885	5	10430 1996 TOXICOLOGY LETTERS 87(1):25-30 Kodam KM; Adav SS; Govindwar SP Effect of sulfamethazine on phenobarbital and benzo[a]pyrene induced hepatic microsomal mixed function oxidase system in rats	1	1
5886	3	9896 1995 VETERINARY AND HUMAN TOXICOLOGY 37(4):340-342 KODAM KM; GOVINDWAR SP EFFECT OF SULFAMETHAZINE ON MIXED-FUNCTION OXIDASE IN CHICKENS	2	2
5887	7	10917 1997 VETERINARY AND HUMAN TOXICOLOGY 39(3):141-146 Kodam KM; Govindwar SP In vivo and in vitro effect of sulfamethazine on hepatic mixed function oxidases in rats	0	0
5888	1	13026 2003 COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 6(2):147-154 Kodzius R; Rhyner C; Konthur Z; Buczek D; Lehrach H; Walter G; Crameri R Rapid identification of allergen-encoding cDNA clones by phage display and high-density arrays	0	0
5889	6	11051 1998 BIOCHEMISTRY 37(38):13184-13193 Koenigs LL; Trager WF Mechanism-based inactivation of cytochrome P450 2B1 by 8- methoxypsoralen and several other furanocoumarins	18	1
5890	6	1998 1972 PLANT PHYSIOLOGY 49(3):353-& KOEPPE DE; MILLER RJ OXIDATION OF REDUCED NICOTINAMIDE ADENINE-DINUCLEOTIDE PHOSPHATE BY ISOLATED CORN MITOCHONDRIA	31	0
5891	10	2257 1973 INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH 5(5):345-351 KOES MT; STASIW RO; FORRESTE.LJ; CHATTOPA.SK; BARTLING GJ; COWAN D; BROWN HD CHARACTERIZATION OF SOLUBILIZED CYTOCHROME-P-450	4	2
5892	3	10006 1996 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 225(2):685-688 Koga N; Kikuichi N; Kanamaru T; Ariyoshi N; Oguri K; Yoshimura H Hamster liver cytochrome P450 (CYP2A8) as a 4-hydroxylase for 2,5,2',5'-tetrachlorabiphenyl	3	1
5893	14	9434 1995 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 317(2):464-470 KOGA N; KIKUICHINISHIMURA N; HARA T; HARADA N; ISHII Y; YAMADA H; OGURI K; YOSHIMURA H PURIFICATION AND CHARACTERIZATION OF A NEWLY IDENTIFIED ISOFORM OF CYTOCHROME-P450 RESPONSIBLE FOR 3-HYDROXYLATION OF 2,5,2',5'-TETRACHLOROBIPHENYL IN HAMSTER LIVER	3	1
5894	6	9539 1995 BIOLOGICAL & PHARMACEUTICAL BULLETIN 18(5):705-710 KOGA N; KIKUICHINISHIMURA N; YOSHIMURA H EFFECT OF CYTOCHROME-P450 INDUCERS ON LIVER MICROSOMAL METABOLISM OF TETRACHLOROBIPHENYLS IN RATS, GUINEA-PIGS AND HAMSTERS	6	2
5895	8	8695 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(24):18267-18271 KOH YC; BUCZKO E; DUFAU ML REQUIREMENT OF PHENYLALANINE-343 FOR THE PREFERENTIAL DELTA-4- LYASE VERSUS DELTA-5-LYASE ACTIVITY OF RAT CYP17	25	12
5896	3	512 1966 EXPERIMENTAL CELL RESEARCH 44(1):175-& KOHEN E; KOHEN C; JENKINS W INFLUENCE OF MICROELECTROPHORETICALLY INTRODUCED METABOLITES ON PYRIDINE NUCLEOTIDE REDUCTION IN GIANT TISSUE CULTURE ASCITES CELLS	28	1
5897	3	736 1968 ACTA PHARMACOLOGICA ET TOXICOLOGICA 26(6):556-& KOHEN E; KOHEN C; THORELL B EFFECT OF CYTOSTATIC DRUGS ON METABOLIC RESPONSE OF ASCITES TUMOR CELLS	2	1
5898	9	1596 1971 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 352(4):635-& KOHEN E; KOHEN C; THORELL B MICROFLUORIMETRIC STUDY OF DRUG INDUCED METABOLIC ADAPTATIONS	3	0
5899	3	3089 1976 EXPERIMENTAL CELL RESEARCH 101(1):47-54 KOHEN E; KOHEN C; THORELL B RAPID AUTOMATIC MICROSPECTROFLUOROMETRIC STUDY OF INTRACELLULAR ENERGY-METABOLISM	7	0
5900	1	1972 1972 MIKROCHIMICA ACTA (1):103-& KOHEN E; KOHEN C; THORELL B; WAGENER G ANALYSIS OF METABOLIC TRANSIENTS IN INTACT CELLS BY RAPID MICROFLUORIMETRY	9	1

#	Cited nodes	Nodes / Authors	GCS	LCS
5901	3	8002 1992 CARCINOGENESIS 13(7):1091-1094 KOHL C; SCHILLER CD; GESCHER A; FARMER PB; BAILEY E ACETOXIME IS METABOLIZED BY HUMAN AND RODENT HEPATIC CYTOCHROME-P450 ENZYMES TO THE GENOTOXICANT AND CARCINOGEN PROPANE 2-NITRONATE	9	0
5902	6	10209 1996 GENOMICS 38(1):96-99 Koike G; VanVooren P; Shiozawa M; Galli J; Li LS; Glaser A; Balasubramanyam A; Brown LJ; Luthman H; Szpirer C; MacDonald MJ; Jacob HJ Genetic mapping and chromosome localization of the rat mitochondrial glycerol-3-phosphate dehydrogenase gene, a candidate for non-insulin-dependent diabetes mellitus	10	1
5903	9	10531 1997 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 232(3):643-647 Koike K; Kusunose E; Nishikawa Y; Ichihara K; Inagaki S; Takagi H; Kikuta Y; Kusunose M Purification and characterization of rabbit small intestinal cytochromes P450 belonging to CYP2J and CYP4A subfamilies	4	4
5904	9	3981 1980 ACTA PHARMACOLOGICA ET TOXICOLOGICA 46(1):37-42 KOIVUSAARI U; LANG M; HIETANEN E DIFFERENCES IN THE RESPONSE OF HEPATIC AND INTESTINAL DRUG- METABOLIZING-ENZYMES IN RATS FOLLOWING CARBON-TETRACHLORIDE AND-OR PHENOBARBITAL TREATMENT	9	1
5905	3	3323 1977 CLINICA CHIMICA ACTA 77(3):301-306 KOIZUMI S; KYOYA S; MIYAWAKI T; KIDANI H; FUNABASHI T; NAKASHIMA H; NAKANUMA Y; OHTA G; ITAGAKI E; KATAGIRI M CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME-ACTIVITY AND CYTOCHROME- P-450 CONTENT IN ADRENAL MITOCHONDRIA OF A PATIENT WITH CONGENITAL LIPOID ADRENAL-HYPERPLASIA (PRADER DISEASE)	42	8
5906	1	3366 1977 HAKKOKOGAKU KAISHI-JOURNAL OF THE SOCIETY OF FERMENTATION TECHNOLOGY 55(5):262-268 KOJIMA M; HATAE K; KURIHARA Y; KATOHGI Y GROWTH AND RESPIRATORY ADAPTATION IN SACCHAROMYCES-SAKE AS AFFECTED BY AROMATIC ALCOHOLS, PARTICULARLY BY 1-PHENYL-1- PROPANOL	0	0
5907	6	7425 1991 BIOCHEMICAL PHARMACOLOGY 42(9):1751-1759 KOJO A; HEISKANEN R; RYTKONEN AL; HONKAKOSKI P; JUVONEN R; LANG M INDUCIBILITY OF P450COH BY PYRAZOLE AND ITS DERIVATIVES	12	9
5908	15	10021 1996 BIOCHEMICAL PHARMACOLOGY 51(9):1137-1143 Kojo A; Pellinen P; Juvonen R; Raunio H; Pelkonen O; Pasanen M Distinct responses of mouse hepatic CYP enzymes to corn oil and peroxisome proliferators	6	0
5909	12	10999 1998 ARCHIVES OF TOXICOLOGY 72(6):336-341 Kojo A; Viitala P; Pasanen M; Pelkonen O; Raunio H; Juvonen R Induction of CYP2A5 by pyrazole and its derivatives in mouse primary hepatocytes	4	2
5910	2	1830 1972 BIOCHIMICA ET BIOPHYSICA ACTA 267(3):457-& KOLAROV J; SUBIK J; KOVAC L OXIDATIVE-PHOSPHORYLATION IN YEAST .8. OSMOTIC AND PERMEABILITY PROPERTIES OF MITOCHONDRIA ISOLATED FROM WILD-TYPE YEAST AND FROM A RESPIRATION-DEFICIENT MUTANT	34	0
5911	9	9150 1994 GASTROENTEROLOGY 106(2):433-439 KOLARS JC; BENEDICT P; SCHMIEDLINREN P; WATKINS PB AFLATOXIN B1-ADDUCT FORMATION IN RAT AND HUMAN SMALL-BOWEL ENTEROCYTES	22	4
5912	24	9329 1994 PHARMACOGENETICS 4(5):247-259 KOLARS JC; LOWN KS; SCHMIEDLINREN P; GHOSH M; FANG C; WRIGHTON SA; MERION RM; WATKINS PB CYP3A GENE-EXPRESSION IN HUMAN GUT EPITHELIUM	173	48
5913	8	7089 1990 HEPATOLOGY 12(6):1371-1378 KOLARS JC; MURRAY SA; PETERS KM; WATKINS PB DIFFERENTIAL REGULATION OF LIVER P-450III-CYTOCHROMES IN CHOLINE-DEFICIENT RATS - IMPLICATIONS FOR THE ERYTHROMYCIN BREATH TEST AS A PARAMETER OF LIVER-FUNCTION	13	5
5914	13	8124 1992 GASTROENTEROLOGY 102(4):1186-1198 KOLARS JC; SCHMIEDLINREN P; DOBBINS WO; SCHUETZ J; WRIGHTON SA; WATKINS PB HETEROGENEITY OF CYTOCHROME-P450IIIA EXPRESSION IN RAT GUT EPITHELIA	55	19
5915	22	8199 1992 JOURNAL OF CLINICAL INVESTIGATION 90(5):1871-1878 KOLARS JC; SCHMIEDLINREN P; SCHUETZ JD; FANG C; WATKINS PB IDENTIFICATION OF RIFAMPIN-INDUCIBLE P450IIIA4 (CYP3A4) IN HUMAN SMALL-BOWEL ENTEROCYTES	276	50
5916	9	8343 1992 TRANSPLANTATION 53(3):596-602 KOLARS JC; STETSON PL; RUSH BD; RUWART MJ; SCHMIEDLINREN P; DUELL EA; VOORHEES JJ; WATKINS PB CYCLOSPORINE METABOLISM BY P450IIIA IN RAT ENTEROCYTES - ANOTHER DETERMINANT OF ORAL BIOAVAILABILITY	77	11
5917	5	8644 1993 GENOMICS 18(3):702-704 KOLBLE K REGIONAL MAPPING OF SHORT TANDEM REPEATS ON HUMAN-CHROMOSOME-10 - CYTOCHROME-P450 GENE CYP2E, D10S196, D10S220, AND D10S225	1	0
5918	26	10063 1996 BIOCHIMIE 78(8-9):752-762 Kolesanova EF; Kiselar JG; Jung C; Kozin SA; Hoa GHB; Archakov AI Antigenic mapping of bacterial and animal cytochromes P-450	5	1
5919	15	10500 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 341(2):229-237 Kolesanova EF; Kozin SA; Rumyantsev AB; Jung C; Hoa GHB; Archakov AI Epitope mapping of cytochrome P450cam (CYP101)	8	0
5920	3	7575 1991 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 16(2):103-106 KOLEVA M; STOYTCHEV T; GULYAEVA L; GRISHANOVA A; MISHIN V; LYAKHOVICH V INDUCTION OF CYTOCHROME-P-450 ISOZYMES UPON REPEATED ADMINISTRATION OF NIFEDIPINE	4	0
5921	14	9719 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(10):5014-5018 KOLEY AP; BUTERS JTM; ROBINSON RC; MARKOWITZ A; FRIEDMAN FK CO BINDING-KINETICS OF HUMAN CYTOCHROME-P450 3A4 - SPECIFIC INTERACTION OF SUBSTRATES WITH KINETICALLY DISTINGUISHABLE CONFORMERS	46	19
5922	12	10562 1997 BIOCHEMISTRY 36(11):3237-3241 Koley AP; Dai RK; Robinson RC; Markowitz A; Friedman FK Differential interaction of erythromycin with cytochromes P450 3A1/2 in the endoplasmic reticulum: A CO flash photolysis study	3	2
5923	3	5258 1985 ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 191():375-386 KOLLER A; JOHNSON PC PYRIDINE-NUCLEOTIDE FLUORESCENCE MEASUREMENTS WITH SIMULTANEOUS VISUALIZATION OF THE MICROCIRCULATION IN SKELETAL-MUSCLE	1	0
5924	2	1704 1971 TOXICOLOGY AND APPLIED PHARMACOLOGY 20(3):299-& KOLMODIN.B; ALEXANDE.B; SJOQVIST F EFFECT OF EXPOSURE TO LINDANE ON DRUG METABOLISM - DECREASED HEXOBARBITAL SLEEPING-TIMES AND INCREASED ANTIPYRINE DISAPPEARANCE RATE IN RATS	31	0
5925	1	88 1960 BIOCHEMISTRY-MOSCOW 25(3):313-319 KOLOTILOVA AI THE REGULATORY SIGNIFICANCE OF THE DPN+-DPNH SYSTEM IN INTERMEDIATE CARBOHYDRATE METABOLISM	0	0
5926	26	5170 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259(5):2991-2999 KOMINAMI S; HARA H; OGISHIMA T; TAKEMORI S INTERACTION BETWEEN CYTOCHROME-P-450 (P-450C21) AND NADPH- CYTOCHROME-P-450 REDUCTASE FROM ADRENOCORTICAL MICROSOMES IN A RECONSTITUTED SYSTEM	43	17
5927	10	9005 1994 BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1192(2):234-240 KOMINAMI S; HARADA D; TAKEMORI S REGULATION MECHANISM OF THE CATALYTIC ACTIVITY OF BOVINE ADRENAL CYTOCHROME P-450(11-BETA)	9	2
5928	16	6483 1989 BIOCHIMICA ET BIOPHYSICA ACTA 985(3):293-299 KOMINAMI S; INOUE S; HIGUCHI A; TAKEMORI S STEROIDOGENESIS IN LIPOSOMAL SYSTEM CONTAINING ADRENAL MICROSOMAL CYTOCHROME-P-450 ELECTRON-TRANSFER COMPONENTS	34	9
5929	9	3603 1978 FEBS LETTERS 89(2):215-218 KOMINAMI S; MORI S; TAKEMORI S PURIFICATION AND OPTICAL STUDIES OF CYTOCHROME-P-450 FROM BOVINE ADRENOCORTICAL MICROSOMES	18	10
5930	24	4137 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(8):3386-3394 KOMINAMI S; OCHI H; KOBAYASHI Y; TAKEMORI S STUDIES ON THE STEROID HYDROXYLATION SYSTEM IN ADRENAL-CORTEX MICROSOMES - PURIFICATION AND CHARACTERIZATION OF CYTOCHROME-P- 450 SPECIFIC FOR STEROID C-21 HYDROXYLATION	144	57
5931	19	8230 1992 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 42(1):57-64 KOMINAMI S; OGAWA N; MORIMUNE R; HUANG DY; TAKEMORI S THE ROLE OF CYTOCHROME-B5 IN ADRENAL MICROSOMAL STEROIDOGENESIS	47	25
5932	14	8436 1993 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 196(2):721-728 KOMORI M A NOVEL P450 EXPRESSED AT THE HIGH-LEVEL IN RAT-BRAIN	31	12
5933	6	8671 1993 JOURNAL OF BIOCHEMISTRY 114(3):445-448 KOMORI M; HIGAMI A; IMAI Y; IMAOKA S; FUNAE Y PURIFICATION AND CHARACTERIZATION OF A FORM OF P450 FROM HORSE LIVER-MICROSOMES	3	0
5934	6	6105 1988 BIOCHEMISTRY 27(1):73-80 KOMORI M; IMAI Y; TSUNASAWA S; SATO R MICROHETEROGENEITY IN THE MAJOR PHENOBARBITAL-INDUCIBLE FORMS OF RABBIT LIVER MICROSOMAL CYTOCHROME-P-450 AS REVEALED BY NUCLEOTIDE SEQUENCING OF CLONED CDNAS	30	25
5935	7	7963 1992 BIOCHIMICA ET BIOPHYSICA ACTA 1131(1):23-29 KOMORI M; KIKUCHI O; KITADA M; KAMATAKI T MOLECULAR-CLONING OF MONKEY P450-1A1 CDNA AND EXPRESSION IN YEAST	24	16
5936	9	7973 1992 BIOCHIMICA ET BIOPHYSICA ACTA 1171(2):141-146 KOMORI M; KIKUCHI O; SAKUMA T; FUNAKI J; KITADA M; KAMATAKI T MOLECULAR-CLONING OF MONKEY LIVER CYTOCHROME-P-450 CDNAS - SIMILARITY OF THE PRIMARY SEQUENCES TO HUMAN CYTOCHROMES-P-450	35	23
5937	7	8553 1993 CARCINOGENESIS 14(8):1683-1688 KOMORI M; KITAMURA R; FUKUTA H; INOUE H; BABA H; YOSHIKAWA K; KAMATAKI T TRANSGENIC DROSOPHILA CARRYING MAMMALIAN CYTOCHROME-P-4501A1 - AN APPLICATION TO TOXICOLOGY TESTING	8	3
5938	6	6385 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 272(1):219-225 KOMORI M; NISHIO K; FUJITANI T; OHI H; KITADA M; MIMA S; ITAHASHI K; KAMATAKI T ISOLATION OF A NEW HUMAN-FETAL LIVER CYTOCHROME-P450 CDNA CLONE - EVIDENCE FOR EXPRESSION OF A LIMITED NUMBER OF FORMS OF CYTOCHROME-P450 IN HUMAN-FETAL LIVERS	68	45
5939	8	6913 1990 BIOCHEMISTRY 29(18):4430-4433 KOMORI M; NISHIO K; KITADA M; SHIRAMATSU K; MUROYA K; SOMA M; NAGASHIMA K; KAMATAKI T FETUS-SPECIFIC EXPRESSION OF A FORM OF CYTOCHROME-P-450 IN HUMAN LIVERS	105	68
5940	3	6623 1989 JOURNAL OF BIOCHEMISTRY 105(2):161-163 KOMORI M; NISHIO K; OHI H; KITADA M; KAMATAKI T MOLECULAR-CLONING AND SEQUENCE-ANALYSIS OF CDNA CONTAINING THE ENTIRE CODING REGION FOR HUMAN-FETAL LIVER CYTOCHROME-P-450	104	81
5941	14	9178 1994 JOURNAL OF BIOCHEMISTRY 116(1):114-120 KOMORI M; ODA Y A MAJOR GLUCOCORTICOID-INDUCIBLE P450 IN RAT-LIVER IS NOT P450 3A1	57	29
5942	1	5516 1985 ZOOLOGICAL SCIENCE 2(4):497-504 KOMUKAI M; FUJIWARA A; YASUMASU I; ASAMI K INHIBITORY EFFECT OF SOME ANTI-INFLAMMATORY COMPOUNDS ON RESPIRATION OF THE SEA-URCHIN EGGS ACTIVATED BY SPERM OR BY MELITTIN	4	0
5943	12	12884 2002 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 303(3):945-951 Kondraganti SR; Jiang WW; Moorthy B Differential regulation of expression of hepatic and pulmonary cytochrome P4501A enzymes by 3-methylcholanthrene in mice lacking the CP1A2 gene	0	0
5944	5	11814 1999 PHARMACEUTICAL RESEARCH 16(6):790-798 Kong ANT; Mandlekar S; Yu R; Lei W; Fasanmande A Pharmacodynamics and toxicodynamics of drug action: Signaling in cell survival and cell death	9	1
5945	6	12458 2001 DRUG METABOLISM REVIEWS 33(3-4):255-271 Kong ANT; Owuor E; Yu R; Hebbar V; Chen C; Hu R; Mandlekar S Induction of xenobiotic enzymes by the map kinase pathway and the antioxidant or electrophile response element (ARE/EpRE)	14	0
5946	10	11928 2000 ARCHIVES OF PHARMACAL RESEARCH 23(1):1-16 Kong ANT; Yu R; Chen C; Mandlekar S; Primiano T Signal transduction events elicited by natural products: Role of MAPK and caspase pathways in homeostatic response and induction of apoptosis	34	1
5947	1	10701 1997 EXERCISE IMMUNOLOGY REVIEW 3():1-31 Konig D; Berg A; Weinstock C; Keul J; Northoff H Essential fatty acids, immune function, and exercise	17	0
5948	7	13081 2003 JOURNAL OF PHARMACY AND PHARMACOLOGY 55(1):143-149 Konishi H; Yoshimoto T; Morita K; Minouchi T; Sato T; Yamaji A Depression of phenytoin metabolic capacity by 5-fluorouracil and doxifluridine in rats	0	0
5949	2	1693 1971 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 68(9):2112-& KONOPKA RJ; BENZER S CLOCK MUTANTS OF DROSOPHILA-MELANOGASTER	655	3
5950	1	4752 1983 ANTIBIOTIKI 28(3):192-194 KONOSHENKO GI; BULGAKOVA VG; POLIN AN HELIOMYCIN EFFECT ON RESPIRATION AND OXIDATIVE-PHOSPHORYLATION OF RAT-LIVER MITOCHONDRIA	0	0
5951	6	5570 1986 BIOCHEMICAL PHARMACOLOGY 35(15):2569-2575 KONTIR DM; GLANCE CA; COLBY HD; MILES PR EFFECTS OF ORGANIC-SOLVENT VEHICLES ON BENZO[A]PYRENE METABOLISM IN RABBIT LUNG MICROSOMES	3	1
5952	15	12889 2002 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 124(20):5684-5691 Koo LS; Immoos CE; Cohen MS; Farmer PJ; de Montellano PRO Enhanced electron transfer and lauric acid hydroxylation by site-directed mutagenesis of CYP119	4	2
5953	2	463 1966 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 115(3):523-& KOOBS DH; MCKEE RW RELATION OF INORGANIC ORTHOPHOSPHATE AND ADENINE DINUCLEOTIDE PHOSPHATE TO CRABTREE EFFECT IN MITOCHONDRIA ISOLATED FROM EHRLICH ASCITES TUMOR CELLS	11	2
5954	5	7679 1991 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 258(3):1072-1076 KOOP DR; CHERNOSKY A; BRASS EP IDENTIFICATION AND INDUCTION OF CYTOCHROME P450 2E1 IN RAT KUPFFER CELLS	33	7
5955	20	4146 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(20):9685-9692 KOOP DR; HOLLENBERG PF KINETICS OF THE HYDROPEROXIDE-DEPENDENT DEALKYLATION REACTIONS CATALYZED BY RABBIT LIVER MICROSOMAL CYTOCHROME-P-450	29	13
5956	7	6769 1989 TOXICOLOGY AND APPLIED PHARMACOLOGY 98(2):278-288 KOOP DR; LAETHEM CL; SCHNIER GG IDENTIFICATION OF ETHANOL-INDUCIBLE P450 ISOZYME-3A (P450IIE1) AS A BENZENE AND PHENOL HYDROXYLASE	111	14
5957	12	6566 1989 DRUG METABOLISM REVIEWS 20(2-4):541-551 KOOP DR; LAETHEM CL; TIERNEY DJ THE UTILITY OF PARA-NITROPHENOL HYDROXYLATION IN P450IIE1 ANALYSIS	84	13
5958	9	4662 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(14):8472-8480 KOOP DR; MORGAN ET; TARR GE; COON MJ PURIFICATION AND CHARACTERIZATION OF A UNIQUE ISOENZYME OF CYTOCHROME-P-450 FROM LIVER-MICROSOMES OF ETHANOL-TREATED RABBITS	490	141
5959	5	10883 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(26):14954-14959 Koopmann E; Hahlbrock K Differentially regulated NADPH : cytochrome P450 oxidoreductases in parsley	9	6
5960	1	413 1965 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 339(1-6):90-& KOPPERSC.G; HOFMANN E ZUR KINETIK DES AEROBEN UND ANAEROBEN GLUCOSESCHWUNDES IN HEFEZELLEN	0	0
5961	7	1149 1969 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 263(2):281-& KORANSKY W; MAGOUR S; NOACK G; HERMANN RS INFLUENCE OF INDUCING AGENTS ON DRUG-OXIDISING AND OTHER REDOX ENZYMES IN LIVER	21	6
5962	2	5823 1987 BIOCHIMICA ET BIOPHYSICA ACTA 893(3):398-408 KORETSKY AP; BALABAN RS CHANGES IN PYRIDINE-NUCLEOTIDE LEVELS ALTER OXYGEN-CONSUMPTION AND EXTRA-MITOCHONDRIAL PHOSPHATES IN ISOLATED-MITOCHONDRIA - A P-31-NMR AND NAD(P)H FLUORESCENCE STUDY	84	5
5963	4	887 1968 JOURNAL OF BIOLOGICAL CHEMISTRY 243(7):1638-& KORNACKE.MS; BALL EG RESPIRATORY PROCESSES IN BROWN ADIPOSE TISSUE	33	0
5964	2	9280 1994 MAGYAR KEMIAI FOLYOIRAT 100(2):62-73 KOROS E THE GROWING ACCEPTANCE OF A NEW IDEA IN CHEMICAL-DYNAMICS	0	0
5965	1	6782 1989 VOPROSY MEDITSINSKOI KHIMII 35(2):97-102 KORSOVA TL; MOROSOVA NA; POZNANSKAYA AA; KURGANOV BI EFFECT OF VITAMIN-B12 COENZYMES ON THE MONOOXYGENASE SYSTEM AND LIPID-PEROXIDATION IN LIVER-TISSUE OF RABBITS POISONED WITH PHENYLHYDRAZINE	0	0
5966	11	2111 1973 BIOCHEMICAL PHARMACOLOGY 22(17):2105-2112 KORTEN K; VANDYKE RA ACUTE INTERACTION OF DRUGS .1. EFFECT OF VOLATILE ANESTHETICS ON KINETICS OF ANILINE HYDROXYLASE AND AMINOPYRINE DEMETHYLASE IN RAT HEPATIC MICROSOMES	15	6
5967	2	1720 1972 ANALYTICA CHIMICA ACTA 61(3):329-& KORYTA J THEORY AND APPLICATIONS OF ION-SELECTIVE ELECTRODES	168	1
5968	7	2169 1973 CHEMICKE LISTY 67(9):897-926 KORYTA J COMPLEXES OF MACROCYCLIC LIGANDS WITH MONOVALENT METALS AND THEIR IMPORTANCE IN CHEMISTRY AND BIOLOGY	10	0
5969	9	11854 1999 TOXICOLOGICAL SCIENCES 47(1):52-61 Korytko PJ; Casey AC; Bush B; Quimby FW Induction of hepatic cytochromes P450 in dogs exposed to a chronic low dose of polychlorinated biphenyls	4	0
5970	14	12099 2000 INSECT MOLECULAR BIOLOGY 9(5):441-449 Korytko PJ; MacIntyre RJ; Scott JG Expression and activity of a house-fly cytochrome P450, CYP6D1, in Drosophila melanogaster	0	0
5971	14	12109 2000 JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 14(1):20-25 Korytko PJ; Quimby FW; Scott JG Metabolism of phenanthrene by house fly CYP6D1 and dog liver cytochrome P450	1	1
5972	5	10994 1998 ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY 37(1):57-63 Korytko PJ; Scott JG CYP6D1 protects thoracic ganglia of houseflies from the neurotoxic insecticide cypermethrin	15	6
5973	28	8796 1993 PHARMACOGENETICS 3(1):1-18 KORZEKWA KR; JONES JP PREDICTING THE CYTOCHROME-P450 MEDIATED METABOLISM OF XENOBIOTICS	79	35
5974	19	11517 1999 BIOCHEMICAL PHARMACOLOGY 57(12):1407-1413 Koskela S; Hakkola J; Hukkanen J; Pelkonen O; Sorri M; Saranen A; Anttila S; Fernandez-Salguero P; Gonzalez F; Raunio H Expression of CYP2A genes in human liver and extrahepatic tissues	32	10
5975	5	2031 1973 AMERICAN JOURNAL OF CLINICAL NUTRITION 26(2):161-164 KOSTELNI.ME; IBER FL CORRELATION OF ALCOHOL AND TOLBUTAMIDE BLOOD CLEARANCE RATES WITH MICROSOMAL ALCOHOL-METABOLIZING ENZYME-ACTIVITY	13	0
5976	3	10089 1996 CARCINOGENESIS 17(3):407-412 Kostka G; KopecSzlezak J; Palut D Early hepatic changes induced in rats by two hepatocarcinogenic organohalogen pesticides: Bromopropylate and DDT	3	0
5977	15	9459 1995 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 322(2):516-520 KOSTRUBSKY VE; STROM SC; WOOD SG; WRIGHTON SA; SINCLAIR PR; SINCLAIR JF ETHANOL AND ISOPENTANOL INCREASE CYP3A AND CYP2E IN PRIMARY CULTURES OF HUMAN HEPATOCYTES	54	9
5978	1	6923 1990 BIOCHEMISTRY-MOSCOW 55(2):143-147 KOTLYAR AB ACTIVATION OF COMPLEX-I IN THE OXIDATION OF NADH AND IN DELTA- MU-H+-DEPENDENT REDUCTION OF NAD+ BY SUCCINATE	0	0
5979	11	7967 1992 BIOCHIMICA ET BIOPHYSICA ACTA 1140(2):169-174 KOTLYAR AB; GUTMAN M THE EFFECT OF DELTA-MU-H+ ON THE INTERACTION OF ROTENONE WITH COMPLEX-I OF SUBMITOCHONDRIAL PARTICLES	13	4
5980	3	7951 1992 BIOCHIMICA ET BIOPHYSICA ACTA 1098(2):144-150 KOTLYAR AB; SLED VD; VINOGRADOV AD EFFECT OF CA2+ IONS ON THE SLOW ACTIVE INACTIVE TRANSITION OF THE MITOCHONDRIAL NADH-UBIQUINONE REDUCTASE	27	7
5981	6	6476 1989 BIOCHEMISTRY-MOSCOW 54(1):1-7 KOTLYAR AB; VINOGRADOV AD HYSTERESIS BEHAVIOR OF COMPLEX-I IN THE DELTA-MU-H+-DEPENDENT REDUCTION OF NAD+ BY SUCCINATE	0	0
5982	12	6931 1990 BIOCHIMICA ET BIOPHYSICA ACTA 1019(2):151-158 KOTLYAR AB; VINOGRADOV AD SLOW ACTIVE INACTIVE TRANSITION OF THE MITOCHONDRIAL NADH- UBIQUINONE REDUCTASE	58	9
5983	11	10738 1997 INTERNATIONAL JOURNAL FOR PARASITOLOGY 27(1):33-40 Kotze AC Cytochrome P450 monooxygenase activity in Haemonchus contortus (Nematoda)	6	0
5984	6	1084 1969 HISTOCHEMIE 20(1):68-& KOUDSTAA.J; HARDONK MJ HISTOCHEMICAL DEMONSTRATION OF ENZYMES RELATED TO NADPH- DEPENDENT HYDROXYLATING SYSTEMS IN RAT LIVER AFTER PHENOBARBITAL TREATMENT	44	0
5985	10	3044 1976 CHEMICO-BIOLOGICAL INTERACTIONS 13(3-4):317-331 KOURI RE; RUDE T; THOMAS PE; WHITMIRE CE STUDIES ON PULMONARY ARYL-HYDROCARBON HYDROXYLASE-ACTIVITY IN INBRED STRAINS OF MICE	29	4
5986	2	5218 1984 PHARMACEUTICA ACTA HELVETIAE 59(12):348-352 KOUROUNAKIS P; HADJIPETROUKOUROUNAKIS L EFFECT OF PREGNENOLONE-16-ALPHA-CARBONITRILE AND OTHER MICROSOMAL-ENZYME INDUCERS ON DRUG-METABOLISM AND SOME PARAMETERS OF ADJUVANT INDUCED DISEASE IN RATS	2	0
5987	2	5651 1986 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 11(4):269-273 KOUROUNAKIS P; REKKA E EFFECT OF BENZOPYRONE DERIVATIVES ON DRUG ACTIVITY AND METABOLISM	3	2
5988	3	3315 1977 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 55(3):363-366 KOUROUNAKIS P; SELYE H ACTIONS OF PREDNISOLONE ACETATE, "PREGNENOLONE-ALPHA-16- CARBONITRILE, AND TRIAMCINOLONE UPON DRUG-RESISTANCE AND METABOLISM - COMPARATIVE-STUDY	3	0
5989	3	2993 1976 BIOCHEMICAL PHARMACOLOGY 25(4):477-481 KOUROUNAKIS P; SZABO S; SELYE H EFFECT OF FLUOROSTEROIDS ON DRUG RESPONSE AND METABOLISM	14	5
5990	2	7063 1990 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 25(8):701-704 KOUROUNAKIS PN; REKKA E STRUCTURAL CONSIDERATIONS OF THE 16-CYANO AND RELATED PREGNENOLONES ON THEIR DRUG METABOLIC INDUCING ACTIVITY	2	1
5991	3	7355 1991 ARCHIV DER PHARMAZIE 324(3):161-164 KOUROUNAKIS PN; REKKA E INDUCTION OF DRUG-METABOLISM CAN BE A HOMEOSTATIC RESPONSE	2	0
5992	5	7574 1991 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 16(1):9-13 KOUROUNAKIS PN; REKKA E; DEMOPOULOS VJ; RETSAS S EFFECT OF THE POSITION OF THE CYANO-GROUP OF CYANOPREGNENOLONES ON THEIR DRUG METABOLIC INDUCING ACTIVITY	0	0
5993	18	1202 1970 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 139(2):370-& KOVAC L; SMIGAN P; HRUSOVSK.E; HESS B INTERACTIONS OF UNCOUPLING AGENTS AND ANTIMYCIN-A WITH CYTOCHROME-B IN YEAST AND HEART MUSCLE PREPARATION UNDER ANAEROBIC CONDITIONS	19	6
5994	1	1490 1971 BIOCHEMICAL MEDICINE 5(5):384-& KOVACH AGB; KOLTAY E; FONYO A; KOVACH E EFFECT OF PHENOXYBENZAMINE ON RESPIRATION OF ISOLATED RAT LIVER MITOCHONDRIA	0	0
5995	3	8143 1992 IZVESTIYA AKADEMII NAUK SSSR SERIYA BIOLOGICHESKAYA (1):31-41 KOVALEV IE; SHIPULINA NB IMMUNOCHEMICAL MECHANISMS OF ORGANISM ADAPTATION TO CHEMICAL SURROUNDINGS	2	0
5996	5	11968 2000 BIOCHEMISTRY-MOSCOW 65(10):1206-1211 Kovaleva IE; Grivennikov SI; Luzikov VN On the effect of cholesterol on the fate of CYP11A1 imported into yeast mitochondria in vivo	0	0
5997	6	13053 2003 EUROPEAN JOURNAL OF BIOCHEMISTRY 270(2):222-229 Kovaleva IE; Novikova LA; Nazarov PA; Grivennikov SI; Luzikov VN Effects of various N-terminal addressing signals on sorting and folding of mammalian CYP11A1 in yeast mitochondria	0	0
5998	2	12520 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(28):26605-26613 Kovalovich K; Li W; DeAngelis R; Greenbaum LE; Ciliberto G; Taub R Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL	22	2
5999	1	1015 1969 BIOCHEMISTRY 8(5):1821-& KOWAL J ADRENAL CELLS IN TISSUE CULTURE .3. EFFECT OF ADRENOCORTICOTROPIN AND 3',5'-CYCLIC ADENOSINE MONOPHOSPHATE ON 11 BETA-HYDROXYLASE AND OTHER STEROIDOGENIC ENZYMES	45	21
6000	2	1876 1972 ENDOCRINOLOGY 91(5):1219-& KOWAL J; ANGEE I; FRENKEL R ADRENAL CELLS IN TISSUE-CULTURE .9. SITE OF ACTH STIMULATION OF GLUCOSE-METABOLISM	7	3

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