#	Cited nodes	Nodes / Authors	GCS	LCS
5101	4	1174 1969 STEROIDS 13(3):327-& JACOBSON M; KUNTZMAN R STUDIES ON TESTOSTERONE HYDROXYLATION AND PENTOBARBITAL OXIDATION BY RAT LIVER MICROSOMES - SELECTIVE EFFECTS OF AGE SEX CASTRATION AND TESTOSTERONE PROPIONATE TREATMENT	74	32
5102	11	2216 1973 DRUG METABOLISM AND DISPOSITION 1(6):766-774 JACOBSON M; LEVIN W; LU AYH; CONNEY AH; KUNTZMAN R RATE OF PENTOBARBITAL AND ACETANILIDE METABOLISM BY LIVER- MICROSOMES - FUNCTION OF LIPID PEROXIDATION AND DEGRADATION OF CYTOCHROME-P-450 HEME	62	14
5103	14	1857 1972 CHEMICO-BIOLOGICAL INTERACTIONS 5(3):183-& JACOBSON M; WEST S; SERNATIN.E; LU AYH; KUNTZMAN R EFFECT OF ALTERING LIVER MICROSOMAL CO-BINDING HEMOPROTEIN COMPOSITION ON PENTOBARBITAL-INDUCED ANESTHESIA	11	3
5104	1	2467 1974 BIOCHIMICA ET BIOPHYSICA ACTA 350(2):277-291 JACOBSON MK; BERNOFSK.C MITOCHONDRIAL ACETALDEHYDE DEHYDROGENASE FROM SACCHAROMYCES- CEREVISIAE	40	0
5105	14	7413 1991 BIOCHEMICAL PHARMACOLOGY 41(12):1911-1919 JACOLOT F; SIMON I; DREANO Y; BEAUNE P; RICHE C; BERTHOU F IDENTIFICATION OF THE CYTOCHROME-P450 IIIA FAMILY AS THE ENZYMES INVOLVED IN THE N-DEMETHYLATION OF TAMOXIFEN IN HUMAN LIVER-MICROSOMES	137	38
5106	2	6364 1989 ARCHIVES FRANCAISES DE PEDIATRIE 46(1):59-65 JACQZAIGRAIN E PHARMACOGENETICS OF DRUG OXIDATION REACTIONS	0	0
5107	1	6545 1989 DEVELOPMENTAL PHARMACOLOGY AND THERAPEUTICS 13(2-4):78-84 JACQZAIGRAIN E GENETIC POLYMORPHISMS OF DRUG-METABOLISM - POSSIBLE IMPLICATIONS DURING DEVELOPMENT	4	2
5108	7	8040 1992 DEVELOPMENTAL PHARMACOLOGY AND THERAPEUTICS 18(3-4):161-168 JACQZAIGRAIN E; CRESTEIL T CYTOCHROME-P450-DEPENDENT METABOLISM OF DEXTROMETHORPHAN - FETAL AND ADULT STUDIES	17	5
5109	7	7410 1991 BIOCHEMICAL PHARMACOLOGY 41(11):1657-1663 JACQZAIGRAIN E; GUEGUEN M; ZANGER UM; ROBIEUX I; ALVAREZ F CYTOCHROME-P450IID SUBFAMILY IN NONHUMAN-PRIMATES - CATALYTICAL AND IMMUNOLOGICAL CHARACTERIZATION	19	7
5110	19	9588 1995 CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY 13(3):211-221 JACQZAIGRAIN E; PANSERAT S; SICA L; KRISHNAMOORTHY R MOLECULAR-GENETICS OF CYTOCHROME-P450-IID - ANOMALIES OF DRUG- METABOLISM	1	0
5111	5	8625 1993 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 45(2-3):101-107 JAHN F; REUTER A; KARGE E; DANZ M; KLINGER W AGE-DEPENDENT DIFFERENT INFLUENCE OF CARBON-TETRACHLORIDE ON BIOTRANSFORMATION OF XENOBIOTICS, GLUTATHIONE CONTENT, LIPID- PEROXIDATION AND HISTOPATHOLOGY OF RAT-LIVER	5	0
5112	5	5947 1987 MOLECULAR ENDOCRINOLOGY 1(4):312-320 JAISWAL AK; GONZALEZ FJ; NEBERT DW COMPARISON OF HUMAN MOUSE P1450 UPSTREAM REGULATORY SEQUENCES IN LIVER-DERIVED AND NONLIVER-DERIVED CELL-LINES	18	10
5113	2	7256 1990 NUCLEIC ACIDS RESEARCH 18(14):4237-4242 JAISWAL AK; HAAPARANTA T; LUC PV; SCHEMBRI J; ADESNIK M GLUCOCORTICOID REGULATION OF A PHENOBARBITAL-INDUCIBLE CYTOCHROME-P-450 GENE - THE PRESENCE OF A FUNCTIONAL GLUCOCORTICOID RESPONSE ELEMENT IN THE 5'-FLANKING REGION OF THE CYP2B2 GENE	50	21
5114	5	5781 1987 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 148(2):857-863 JAISWAL AK; NEUHOLD LA; NEBERT DW HUMAN P450IA1 UPSTREAM REGULATORY SEQUENCES EXPRESSING THE CHLORAMPHENICOL ACETYLTRANSFERASE GENE - EFFECT OF HA-MSV ENHANCER AND COMPARISON OF TRANSIENT WITH STABLE TRANSFORMATION ASSAYS	4	3
5115	7	9785 1995 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 55(5-6):555-563 Jakob F; Homann D; Adamski J Expression and regulation of aromatase and 17 beta- hydroxysteroid dehydrogenase type 4 in human THP 1 leukemia cells	8	1
5116	7	10799 1997 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 61(3-6):167-174 Jakob F; Siggelkow H; Homann D; Kohrle J; Adamski J; Schutze N Local estradiol metabolism in osteoblast- and osteoclast-like cells	19	0
5117	10	1209 1970 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 39(6):1073-& JAKOBSSO.S FATTY ACID INDUCIBLE CYTOCHROME P-454 OF RAT KIDNEY CORTEX MICROSOMES	61	0
5118	18	2069 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 158(2):556-565 JAKOBSSO.S; GRUNDIN R; THOR H INDUCTION OF MICROSOMAL ARYL HYDROCARBON (3,4- BENZO(ALPHA)PYRENE) HYDROXYLASE AND CYTOCHROME P-450K IN RAT- KIDNEY CORTEX .2. INTERACTIONS WITH INDUCED HEMOPROTEIN	9	0
5119	11	2315 1973 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 185(2):226-234 JAKOBSSO.SV; CINTI DL STUDIES ON CYTOCHROME P-450-CONTAINING MONO-OXYGENASE SYSTEM IN HUMAN KIDNEY-CORTEX MICROSOMES	43	0
5120	3	4685 1982 MICROBIOS 34(135):17-30 JAMES AM; DJAVAN A MICRO-CALORIMETRIC STUDIES OF KLEBSIELLA-AEROGENES GROWN IN CHEMOSTAT CULTURE .3. TRANSIENT (NON-STEADY) STATE	3	0
5121	14	11140 1998 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 121(1-3):157-172 James MO; Boyle SM Cytochromes P450 in crustacea	10	2
5122	13	9959 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 329(1):31-38 James MO; Boyle SM; TrapidoRosenthal HG; Smith WC; Greenberg RM; Shiverick KT cDNA and protein sequence of a major form of P450, CYP2L, in the hepatopancreas of the spiny lobster, Panulirus argus	14	12
5123	5	4409 1981 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 217(1):127-132 JAMES R; DESMOND P; KUPFER A; SCHENKER S; BRANCH RA THE DIFFERENTIAL LOCALIZATION OF VARIOUS DRUG-METABOLIZING SYSTEMS WITHIN THE RAT-LIVER LOBULE AS DETERMINED BY THE HEPATOTOXINS ALLYL ALCOHOL, CARBON-TETRACHLORIDE AND BROMOBENZENE	70	4
5124	10	2702 1975 BIOCHEMICAL PHARMACOLOGY 24(8):835-838 JAMES RC; FRANKLIN MR COMPARISONS OF FORMATION OF CYTOCHROME-P-450 COMPLEXES ABSORBING AT 455 NM IN RABBIT AND RAT MICROSOMES	22	18
5125	9	3699 1978 TOXICOLOGY AND APPLIED PHARMACOLOGY 44(1):63-73 JAMES RC; FRANKLIN MR TRIPHASIC AMPHETAMINE LETHAL DOSE CURVE IN MICE AND ITS POSSIBLE RELATIONSHIP TO DRUG-METABOLISM	2	0
5126	4	12082 2000 FITOTERAPIA 71(1):25-33 Janbaz KH; Gilani AH Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents	1	0
5127	5	11366 1998 PHARMACOLOGICAL RESEARCH 38(3):215-219 Janbaz KH; Saeed SA; Gilani AH An assessment of the potential of protopine to inhibit microsomal drug metabolising enzymes and prevent chemical- induced hepatotoxicity in rodents	0	0
5128	11	7227 1990 MOLECULAR ENDOCRINOLOGY 4(2):295-303 JANECZKO R; WAXMAN DJ; LEBLANC GA; MORVILLE A; ADESNIK M HORMONAL-REGULATION OF LEVELS OF THE MESSENGER-RNA ENCODING HEPATIC P450 2C (IIC11), A CONSTITUTIVE MALE-SPECIFIC FORM OF CYTOCHROME-P450	29	13
5129	14	11369 1998 PHARMACOLOGY 56(3):150-157 Jang GR; Benet LZ Antiprogestin-mediated inactivation of cytochrome P450 3A4	6	2
5130	6	6130 1988 BIOMEDICA BIOCHIMICA ACTA 47(7):565-579 JANIG GR; KRAFT R; RABE H; MAKOWER A; RUCKPAUL K COMPARATIVE STUDIES ON THE ACCESSIBILITY AND FUNCTIONAL IMPORTANCE OF TYROSINE RESIDUES IN CYTOCHROME-P-450 ISOZYMES	3	1
5131	6	3334 1977 CROATICA CHEMICA ACTA 49(2):263-270 JANIG GR; MISSELWITZ R; ZIRWER D; BUDER E; REIN H; RUCKPAUL K DIFFERENTIATION BETWEEN TYPE-I AND TYPE-II SUBSTRATE BINDING TO CYTOCHROME-P450 BY TEMPERATURE STUDIES	3	1
5132	30	3674 1978 PHARMAZIE 33(6):313-317 JANIG GR; PFEIL D LIVER MICROSOMAL MONO-OXYGENASE SYSTEM - FUNCTIONAL COMPONENTS AND THEIR PROPERTIES	5	2
5133	13	3724 1979 ACTA BIOLOGICA ET MEDICA GERMANICA 38(2-3):409-422 JANIG GR; PFEIL D; RUCKPAUL K ENZYMATIC-ACTIVITIES OF MATRIX-BOUND COMPONENTS OF THE LIVER MICROSOMAL CYTOCHROME-P-450 SYSTEM	9	4
5134	30	8192 1992 JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS 580(1-2):325-346 JANSEN EHJM; DEFLUITER P DETECTION OF THE ENZYMATIC-ACTIVITY OF CYTOCHROME-P-450 ENZYMES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY	8	4
5135	17	10270 1996 JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS 684(1-2):133-145 Jansen EHJM; Laan CA; deFluiter P Advances in sample preparation, electrophoretic separation and detection methods for rat cytochrome P450 enzymes	0	0
5136	7	6615 1989 INTERNATIONAL JOURNAL OF DERMATOLOGY 28(8):493-496 JANSSEN PAJ; VANDENBOSSCHE HFA; VANWAUWE JP; CAUWENBERGH GFMJ; DEGREEF HJ THE ROLE OF CYTOCHROME-P-450 IN DERMATOLOGY	9	3
5137	19	5436 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260(11):7084-7093 JANSSON I; MOLE J; SCHENKMAN JB PURIFICATION AND CHARACTERIZATION OF A NEW FORM (RLM2) OF LIVER MICROSOMAL CYTOCHROME-P-450 FROM UNTREATED RAT	98	57
5138	9	9423 1995 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 316(1):275-284 JANSSON I; MOLE JE; SCHENKMAN JB THE ISOLATION AND COMPARISON OF MULTIPLE FORMS OF CYP2B FROM UNTREATED AND PHENOBARBITAL-TREATED RABBIT LIVER-MICROSOMES	7	5
5139	15	2333 1973 MOLECULAR PHARMACOLOGY 9(6):840-845 JANSSON I; SCHENKMAN JB EVIDENCE AGAINST PARTICIPATION OF CYTOCHROME B5 IN HEPATIC MICROSOMAL MIXED-FUNCTION OXIDASE REACTION	34	33
5140	24	2887 1975 MOLECULAR PHARMACOLOGY 11(4):450-461 JANSSON I; SCHENKMAN JB STUDIES ON 3 MICROSOMAL ELECTRON-TRANSFER ENZYME-SYSTEMS - EFFECTS OF ALTERATION OF COMPONENT ENZYME LEVELS INVIVO AND INVITRO	80	30
5141	34	3241 1977 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 178(1):89-107 JANSSON I; SCHENKMAN JB STUDIES ON 3 MICROSOMAL ELECTRON-TRANSFER ENZYME-SYSTEMS .2. SPECIFICITY OF ELECTRON FLOW PATHWAYS	90	47
5142	17	3482 1978 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 185(1):251-261 JANSSON I; SCHENKMAN JB INFLUENCES OF SUBSTRATES OF DIFFERENT MICROSOMAL ELECTRON- TRANSFER PATHWAYS ON OXIDATION-REDUCTION KINETICS OF MICROSOMAL CYTOCHROME-B5	23	16
5143	19	4343 1981 DRUG METABOLISM AND DISPOSITION 9(5):461-465 JANSSON I; SCHENKMAN JB STOICHIOMETRY OF AMINOPYRINE DEMETHYLATION WITH AND WITHOUT NADH SYNERGISM	3	1
5144	26	4479 1982 ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 136():145-163 JANSSON I; SCHENKMAN JB POSSIBLE MECHANISM OF COUPLED NADPH OXIDASE AND P-450 MONO- OXYGENASE ACTION	0	0
5145	11	9942 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 325(2):265-269 Jansson I; Schenkman JB Substrate influence on interaction between cytochrome P450 and cytochrome b(5) in microsomes	8	6
5146	11	1748 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 151(2):391-& JANSSON I; SCHENKMAN JB; ERNSTER L; ORRENIUS S STUDY OF INTERACTION OF A SERIES OF SUBSTITUTED BARBITURIC ACIDS WITH HEPATIC MICROSOMAL MONOOXYGENASE	68	44
5147	8	12251 2000 TOXICOLOGY 144(1-3):211-219 Jansson I; Stoilov I; Sarfarazi M; Schenkman JB Enhanced expression of CYP1B1 in Escherichia coli	7	4
5148	13	12620 2001 PHARMACOGENETICS 11(9):793-801 Jansson I; Stoilov I; Sarfarazi M; Schenkman JB Effect of two mutations of human CYP1B1, G61E and R469W, on stability and endogenous steroid substrate metabolism	4	0
5149	20	5373 1985 DRUG METABOLISM AND DISPOSITION 13(4):453-458 JANSSON I; TAMBURINI PP; FAVREAU LV; SCHENKMAN JB THE INTERACTION OF CYTOCHROME-B5 WITH 4 CYTOCHROME-P-450 ENZYMES FROM THE UNTREATED RAT	58	30
5150	8	8876 1993 XENOBIOTICA 23(2):169-179 JAPENGA AC; DAVIES S; PRICE RJ; LAKE BG EFFECT OF TREATMENT WITH PYRAZINE AND SOME DERIVATIVES ON CYTOCHROME-P450 AND SOME ENZYME-ACTIVITIES IN RAT-LIVER	17	8
5151	5	2517 1974 EUROPEAN JOURNAL OF BIOCHEMISTRY 43(1):79-85 JAPUNDZI.I; JAPUNDZI.M; SZABO S INDUCTION OF ETHYLMORPHINE DEMETHYLATION AND ANILINE PARA- HYDROXYLATION BY VARIOUS CATATOXIC STEROIDS IN REGENERATING RAT-LIVER	8	0
5152	5	3405 1977 JOURNAL OF CELL BIOLOGY 73(1):223-241 JARASCH ED; BRUDER G; KEENAN TW; FRANKE WW REDOX CONSTITUENTS IN MILK-FAT GLOBULE MEMBRANES AND ROUGH ENDOPLASMIC-RETICULUM FROM LACTATING MAMMARY-GLAND	70	3
5153	9	3893 1979 JOURNAL OF CELL BIOLOGY 80(1):37-52 JARASCH ED; KARTENBECK J; BRUDER G; FINK A; MORRE DJ; FRANKE WW B-TYPE CYTOCHROMES IN PLASMA-MEMBRANES ISOLATED FROM RAT-LIVER, IN COMPARISON WITH THOSE OF ENDOMEMBRANES	90	8
5154	3	33 1958 BIOCHIMICA ET BIOPHYSICA ACTA 29(1):123-132 JARNEFELT J; BASFORD RE; TISDALE HD; GREEN DE STUDIES ON THE TERMINAL ELECTRON TRANSPORT SYSTEM .12. FRAGMENTATION OF THE SUCCINIC DEHYDROGENASE COMPLEX	23	2
5155	16	11485 1999 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 369(1):89-99 Jarukamjorn K; Sakuma T; Miyaura JI; Nemoto N Different regulation of the expression of mouse hepatic cytochrome P4502B enzymes by glucocorticoid and phenobarbital	10	3
5156	7	11945 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 279(1):288-292 Jarukamjorn K; Sakuma T; Nemoto N Discriminating activation of CYP2B9 expression in male C57BL/6 mouse liver by beta-estradiol	4	0
5157	25	12354 2001 BIOCHEMICAL PHARMACOLOGY 62(2):161-169 Jarukamjorn K; Sakuma T; Yamamoto M; Ohara A; Nemoto N Sex-associated expression of mouse hepatic and renal CYP2B enzymes by glucocorticoid hormones	3	0
5158	10	7811 1991 XENOBIOTICA 21(9):1091-1106 JAUREGUI HO; NG SF; GANN KL; WAXMAN DJ XENOBIOTIC INDUCTION OF P-450 PB-4 (IIB1) AND P-450C (IA1) AND ASSOCIATED MONOOXYGENASE ACTIVITIES IN PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES	34	3
5159	9	8473 1993 BIOCHEMICAL PHARMACOLOGY 46(3):493-501 JAW S; JEFFERY EH INTERACTION OF CAFFEINE WITH ACETAMINOPHEN .1. CORRELATION OF THE EFFECT OF CAFFEINE ON ACETAMINOPHEN HEPATOTOXICITY AND ACETAMINOPHEN BIOACTIVATION FOLLOWING TREATMENT OF MICE WITH VARIOUS CYTOCHROME-P450 INDUCING AGENTS	11	1
5160	7	5795 1987 BIOCHEMICAL PHARMACOLOGY 36(15):2481-2487 JAYYOSI Z; TOTIS M; SOUHAILI H; GOULONGINET C; LIVERTOUX MH; BATT AM; SIEST G INDUCTION OF HEPATIC CYTOCHROME-P-450C-DEPENDENT MONOOXYGENASE ACTIVITIES BY DANTROLENE IN RAT	5	1
5161	11	9076 1994 DNA AND CELL BIOLOGY 13(8):781-792 JEAN A; REISS A; DESROCHERS M; DUBOIS S; TROTTIER E; TROTTIER Y; WIRTANEN L; ADESNIK M; WAXMAN DJ; ANDERSON A RAT-LIVER CYTOCHROME-P450 2B3 - STRUCTURE OF THE CYP2B3 GENE AND IMMUNOLOGICAL IDENTIFICATION OF A CONSTITUTIVE P450 2B3- LIKE PROTEIN IN RAT-LIVER	14	5
5162	4	6176 1988 DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY 7(5):361-369 JEAN A; RIVKIN E; ANDERSON A SIMPLE SEQUENCE DNA ASSOCIATED WITH NEAR SEQUENCE IDENTITY OF THE 3'-FLANKING REGIONS OF RAT CYTOCHROME-P450B AND CYTOCHROME- P450E GENES	13	9
5163	6	10890 1997 PROTEINS-STRUCTURE FUNCTION AND GENETICS 28(3):388-404 Jean P; Pothier J; Dansette PM; Mansuy D; Viari A Automated multiple analysis of protein structures: Application to homology modeling of cytochromes P450	7	3
5164	11	3404 1977 JOURNAL OF BIOLOGICAL CHEMISTRY 252(24):8788-8796 JEFCOATE CR CYTOCHROME-P-450 OF ADRENAL MITOCHONDRIA - STEROID BINDING- SITES ON 2 DISTINGUISHABLE FORMS OF RAT ADRENAL MITOCHONDRIAL CYTOCHROME-P-450SCC	37	12
5165	9	4652 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(9):4731-4737 JEFCOATE CR PH MODULATION OF LIGAND-BINDING TO ADRENAL MITOCHONDRIAL CYTOCHROME P-450SCC	25	7
5166	8	1588 1971 FEBS LETTERS 12(5):279-& JEFCOATE CR; BOYD GS PH-DEPENDENT CHANGES IN SPIN STATE OF CYTOCHROME P450 FROM ADRENAL MITOCHONDRIA	33	19
5167	8	1388 1970 MOLECULAR PHARMACOLOGY 6(4):391-& JEFCOATE CR; CALABRES.RL; GAYLOR JL LIGAND INTERACTION WITH HEMOPROTEIN P-450 .3. USE OF NORMAL- OCTYLAMINE AND ETHYL ISOCYANIDE DIFFERENCE SPECTROSCOPY IN QUANTITATIVE DETERMINATION OF HIGH-SPIN AND LOW-SPIN P-450	71	0
5168	10	1020 1969 BIOCHEMISTRY 8(8):3464-& JEFCOATE CR; GAYLOR JL LIGAND INTERACTIONS WITH HEMOPROTEIN P-450 .2. INFLUENCE OF PHENOBARBITAL AND METHYLCHOLANTHRENE INDUCTION PROCESSES ON P- 450 SPECTRA	156	0
5169	11	1256 1970 BIOCHEMISTRY 9(19):3816-& JEFCOATE CR; GAYLOR JL LIGAND INTERACTIONS WITH HEMOPROTEIN-P-450 - EQUILIBRIA BETWEEN HIGH-SPIN AND LOW-SPIN FORMS OF P-450 IN BOVINE ADRENAL MITOCHONDRIA	23	18
5170	11	1019 1969 BIOCHEMISTRY 8(8):3455-& JEFCOATE CR; GAYLOR JL; CALABRES.RL LIGAND INTERACTIONS WITH CYTOCHROME P-450 .I. BINDING OF PRIMARY AMINES	229	0
5171	7	1307 1970 FEBS LETTERS 9(1):41-& JEFCOATE CR; HUME R; BOYD GS SEPARATION OF 2 FORMS OF CYTOCHROME-P450 ADRENAL CORTEX MITOCHONDRIA	102	63
5172	28	5638 1986 ENDOCRINE RESEARCH 12(4):315-350 JEFCOATE CR; MCNAMARA BC; DIBARTOLOMEIS MJ CONTROL OF STEROID-SYNTHESIS IN ADRENAL FASCICULATA CELLS	39	8
5173	10	2851 1975 JOURNAL OF BIOLOGICAL CHEMISTRY 250(12):4671-4677 JEFCOATE CR; ORMEJOHNSON WH CYTOCHROME-P-450 OF ADRENAL MITOCHONDRIA - INVITRO AND INVIVO CHANGES IN SPIN STATES	39	9
5174	16	2516 1974 EUROPEAN JOURNAL OF BIOCHEMISTRY 42(2):539-551 JEFCOATE CR; SIMPSON ER; BOYD GS SPECTRAL PROPERTIES OF RAT ADRENAL-MITOCHONDRIAL CYTOCHROME-P- 450	132	40
5175	19	2046 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):243-261 JEFCOATE CR; SIMPSON ER; BOYD GS; BROWNIE AC; ORMEJOHN.WH DETECTION OF DIFFERENT STATES OF P-450 CYTOCHROMES IN ADRENAL MITOCHONDRIA - CHANGES INDUCED BY ACTH	74	33
5176	14	11285 1998 JOURNAL OF CLINICAL PSYCHIATRY 59():31-39 Jefferson JW Drug and diet interactions: Avoiding therapeutic paralysis	10	0
5177	16	11286 1998 JOURNAL OF CLINICAL PSYCHIATRY 59():37-47 Jefferson JW Drug interactions - Friend or foe?	17	2
5178	6	2596 1974 MOLECULAR PHARMACOLOGY 10(6):1004-1008 JEFFERY E; MANNERIN.GJ DISCREPANCY IN MEASUREMENT OF REDUCED TRIPHOSPHOPYRIDINE NUCLEOTIDE OXIDIZED DURING ETHYLMORPHINE N-DEMETHYLATION DUE TO PRESENCE OF A NUCLEOTIDE PYROPHOSPHATASE	25	14
5179	5	4967 1983 MOLECULAR PHARMACOLOGY 23(2):467-473 JEFFERY EH THE EFFECT OF ZINC ON NADPH OXIDATION AND MONOOXYGENASE ACTIVITY IN RAT HEPATIC MICROSOMES	30	0
5180	12	3923 1979 MOLECULAR PHARMACOLOGY 15(2):396-409 JEFFERY EH; MANNERING GJ MECHANISM OF THE NUCLEOTIDE PYROPHOSPHATASE INDUCED DISTORTION OF STOICHIOMETRY OF TPNH UTILIZATION AND PRODUCT FORMATION BY HEPATIC CYTOCHROME-P-450 LINKED N-DEMETHYLASE SYSTEMS	7	4
5181	9	4970 1983 MOLECULAR PHARMACOLOGY 23(3):748-757 JEFFERY EH; MANNERING GJ INTERACTION OF CONSTITUTIVE AND PHENOBARBITAL-INDUCED CYTOCHROME-P-450 ISOZYMES DURING THE SEQUENTIAL OXIDATION OF BENZPHETAMINE - EXPLANATION FOR THE DIFFERENCE IN BENZPHETAMINE-INDUCED HYDROGEN-PEROXIDE PRODUCTION AND 455-NM COMPLEX-FORMATION IN MICROSOMES FROM UNTREATED AND PHENOBARBITAL-TREATED RATS	11	3
5182	7	11061 1998 BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1395(3):259-265 Jehan F; Ismail R; Hanson K; DeLuca HF Cloning and expression of the chicken 25-hydroxyvitamin D-3 24- hydroxylase cDNA	2	0
5183	6	7134 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(14):8190-8197 JELINEK DF; ANDERSSON S; SLAUGHTER CA; RUSSELL DW CLONING AND REGULATION OF CHOLESTEROL 7-ALPHA-HYDROXYLASE, THE RATE-LIMITING ENZYME IN BILE-ACID BIOSYNTHESIS	231	22
5184	1	1127 1969 JOURNAL OF ENDOCRINOLOGY 45(1):75-& JELLINCK PH; GARLAND M ENDOCRINE CONTROL OF METABOLISM OF OESTRADIOL BY RAT LIVER MICROSOMES	15	0
5185	7	2776 1975 CHEMICO-BIOLOGICAL INTERACTIONS 11(5):459-468 JELLINCK PH; SMITH G; NEWCOMBE AM INHIBITION OF HEPATIC ARYL-HYDROCARBON HYDROXYLASE BY 3- METHYLCHOLANTHRENE, 7,8-BENZOFLAVONE AND OTHER INDUCERS ADDED INVITRO	16	1
5186	9	8772 1993 MOLECULAR AND CELLULAR ENDOCRINOLOGY 97(1-2):R1-R6 JENKINS C; MICHAEL D; MAHENDROO M; SIMPSON E EXON-SPECIFIC NORTHERN ANALYSIS AND RAPID AMPLIFICATION OF CDNA ENDS (RACE) REVEAL THAT THE PROXIMAL PROMOTER-II (PII) IS RESPONSIBLE FOR AROMATASE CYTOCHROME-P-450 (CYP19) EXPRESSION IN HUMAN OVARY	28	14
5187	9	10754 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272(36):22509-22513 Jenkins CM; Genzor CG; Fillat MF; Waterman MR; GomezMoreno C Negatively charged Anabaena flavodoxin residues (Asp(144) and Glu(145)) are important for reconstitution of cytochrome P450 17 alpha-hydroxylase activity	13	5
5188	14	10514 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 347(1):93-102 Jenkins CM; Pikuleva I; Kagawa N; Waterman MR Escherichia coli flavodoxin sepharose as an affinity resin for cytochromes P450 and use to identify a putative cytochrome p450c17 3 beta-hydroxysteroid dehydrogenase interaction	4	2
5189	19	9206 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(44):27401-27408 JENKINS CM; WATERMAN MR FLAVODOXIN AND NADPH-FLAVODOXIN REDUCTASE FROM ESCHERICHIA-COLI SUPPORT BOVINE CYTOCHROME P450C17 HYDROXYLASE-ACTIVITIES	78	49
5190	28	11043 1998 BIOCHEMISTRY 37(17):6106-6113 Jenkins CM; Waterman MR NADPH-Flavodoxin reductase and flavodoxin from Escherichia coli: Characteristics as a soluble microsomal P450 reductase	23	12
5191	13	11621 1999 DRUG METABOLISM REVIEWS 31(1):195-203 Jenkins CM; Waterman MR Flavodoxin as a model for the P450-interacting domain of NADPH cytochrome P450 reductase	0	0
5192	2	10727 1997 HUMAN GENETICS 99(2):248-250 Jenkins MM; Prchal JT A high-frequency polymorphism of NADH-cytochrome b5 reductase in African-Americans	1	1
5193	3	11894 2000 AMERICAN JOURNAL OF CLINICAL NUTRITION 72(2):670S-674S Jenkins RR Exercise and oxidative stress methodology: a critique	4	0
5194	9	7353 1991 AQUATIC TOXICOLOGY 21(1-2):81-91 JENSEN EG; SKAARE JU; EGAAS E; GOKSOYR A RESPONSE OF XENOBIOTIC METABOLIZING ENZYMES IN RAINBOW-TROUT (ONCORHYNCHUS-MYKISS) TO ENDOSULFAN, DETECTED BY ENZYME- ACTIVITIES AND IMMUNOCHEMICAL METHODS	19	6
5195	6	8555 1993 CARCINOGENESIS 14(10):2115-2118 JENSEN KG; ONFELT A; POULSEN HE; DOEHMER J; LOFT S EFFECTS OF BENZO[A]PYRENE AND (PLUS-OR-MINUS)-TRANS-7,8- DIHYDROXY-7,8-DIHYDROBENZO[A]PYRENE ON MITOSIS IN CHINESE- HAMSTER V79 CELLS WITH STABLE EXPRESSION OF RAT CYTOCHROME P4501A1 OR 1A2	19	3
5196	4	12191 2000 MUTAGENESIS 15(1):9-15 Jensen KG; Wiberg K; Klasson-Wehler E; Onfelt A Induction of aberrant mitosis with PCBs: particular efficiency of 2,3,3 ',4,4 '-pentachlorobiphenyl and synergism with triphenyltin	0	0
5197	3	494 1966 BIOCHIMICA ET BIOPHYSICA ACTA 122(2):157-& JENSEN PK ANTIMYCIN-INSENSITIVE OXIDATION OF SUCCINATE AND REDUCED NICOTINAMIDE-ADENINE DINUCLEOTIDE IN ELECTRON-TRANSPORT PARTICLES .I. PH DEPENDENCY AND HYDROGEN PEROXIDE FORMATION	19	5
5198	1	10110 1996 CHEMOSPHERE 32(11):2115-2125 Jenssen BM; Skaare JU Organochlorine compounds in blubber, liver and brain in neonatal grey seal pups	19	0
5199	9	12816 2002 FOOD AND CHEMICAL TOXICOLOGY 40(11):1685-1692 Jeong HG; Kim JY Effects of o,p '-DDT on the 2,3,7,8-tetrachlorodibenzo-p- dioxin-inducible CYP1A1 expression in murine Hepa-lc1c7 cells	0	0
5200	8	11944 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 277(3):594-598 Jeong HG; Kim JY; Choi CY Down-regulation of murine Cyp1a-1 in mouse hepatoma Hepa-1c1c7 cells by bisphenol A	2	0

#	Cited nodes	Nodes / Authors	GCS	LCS
5201	9	12396 2001 CANCER LETTERS 165(1):95-101 Jeong HG; Kim JY; Choi CY; You HJ; Hahm KS Suppression of CYP1A1 expression by 4-nonylphenol in murine Hepa-1c1c7 cells	2	0
5202	11	11094 1998 CANCER LETTERS 133(2):177-184 Jeong HG; Lee SS Suppressive effects of estradiol on 2,3,7,8-tetrachlorodibenzo- p-dioxin-mediated transcriptional activation of murine Cyp1a-1 in mouse hepatoma Hepa 1c1c7 cells	10	3
5203	8	11562 1999 CANCER LETTERS 138(1-2):131-137 Jeong HG; Lee SS Suppressive effects of alpha-Hederin on 2,3,7,8- tetrachlorodibenzo-p-dioxin-mediated murine Cypla-1 expression in the mouse hepatoma Hepa-1c1c7 cells	2	0
5204	6	2686 1975 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 64(3):814-822 JERNSTROM B; CAPDEVILA J; JAKOBSSON S; ORRENIUS S SOLUBILIZATION AND PARTIAL-PURIFICATION OF CYTOCHROME-P-450 FROM RAT LUNG MICROSOMES	16	7
5205	9	3037 1976 CANCER RESEARCH 36(11):4107-4113 JERNSTROM B; VADI H; ORRENIUS S FORMATION IN ISOLATED RAT-LIVER MICROSOMES AND NUCLEI OF BENZO(A)PYRENE METABOLITES THAT BIND TO DNA	82	9
5206	2	12388 2001 BRAIN RESEARCH 895(1-2):264-267 Jevtovic-Todorovic V; Wozniak DF; Benshoff ND; Olney JW A comparative evaluation of the neurotoxic properties of ketamine and nitrous oxide	6	0
5207	13	6792 1989 XENOBIOTICA 19(10):1181-1200 JEWELL CSE; CUMMINGS LE; RONIS MJJ; WINSTON GW THE HEPATIC-MICROSOMAL MIXED-FUNCTION OXYGENASE (MFO) SYSTEM OF ALLIGATOR-MISSISSIPPIENSIS - INDUCTION BY 3-METHYLCHOLANTHRENE (MC)	25	7
5208	8	6538 1989 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 92(2):329-339 JEWELL CSE; WINSTON GW CHARACTERIZATION OF THE MICROSOMAL MIXED-FUNCTION OXYGENASE SYSTEM OF THE HEPATOPANCREAS AND GREEN GLAND OF THE RED SWAMP CRAYFISH, PROCAMBARUS-CLARKII	25	7
5209	1	10554 1997 BIOCHEMICAL PHARMACOLOGY 54(6):639-647 Jez JM; Flynn TG; Penning TM A new nomenclature for the aldo-keto reductase superfamily	117	1
5210	6	11293 1998 JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 5(1-4):371-377 Jezequel SG Microbial models of mammalian metabolism: uses and misuses (clarification of some misconceptions)	1	0
5211	6	6510 1989 CANCER RESEARCH 49(19):5299-5304 JI C; MIRVISH SS; NICKOLS J; ISHIZAKI H; LEE MJ; YANG CS FORMATION OF HYDROXY DERIVATIVES, ALDEHYDES, AND NITRITE FROM N-NITROSOMETHYL-NORMAL-AMYLAMINE BY RAT-LIVER MICROSOMES AND BY PURIFIED CYTOCHROME-P-450 IIB1	22	6
5212	6	11774 1999 LIFE SCIENCES 65(12):1257-1264 Jiang HB; Ichikawa Y Neuronal nitric oxide synthase catalyzes the reduction of 7- ethoxyresorufin	4	0
5213	3	11378 1998 PHYTOCHEMISTRY 49(2):387-394 Jiao Y; Davin LB; Lewis NG Furanofuran lignan metabolism as a function of seed maturation in Sesamum indicum: Methylenedioxy bridge formation	3	0
5214	1	545 1966 JOURNAL OF BIOLOGICAL CHEMISTRY 241(22):5366-& JICK H; SHUSTER L TURNOVER OF MICROSOMAL REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE-CYTOCHROME C REDUCTASE IN LIVERS OF MICE TREATED WITH PHENOBARBITAL	117	18
5215	1	5551 1986 ARCHIVOS DE INVESTIGACION MEDICA 17(3):313-321 JIMENEZCARDOSO JM; ALCANTARA G; CAMPOS E; CARABEZ A; WUSTERHAUS A LIGHT AND ELECTRON-MICROSCOPY OF HEPATOCYTE OF RATS TREATED WITH PEREZONE - PRELIMINARY-REPORT	0	0
5216	24	10989 1998 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 359(1):89-98 Jin RY; Koop DR; Raucy JL; Lasker JM Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4	14	7
5217	2	1867 1972 COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS 37(8):2649-& JINDRA A; SIPAL Z OXIDATION OF TOLUENE BY MICROSOMAL MONOOXYGENASE SYSTEM OF RAT- LIVER	0	0
5218	12	13038 2003 DRUG METABOLISM AND DISPOSITION 31(4):398-403 Jinno H; Tanaka-Kagawa T; Ohno A; Makino Y; Matsushima E; Hanioka N; Ando M Functional characterization of cytochrome P4502B6 allelic variants	0	0
5219	9	4414 1981 JOURNAL OF RADIOANALYTICAL CHEMISTRY 65(1-2):139-154 JIROUSEK L ON THE CHEMICAL NATURE OF IODINATING SPECIES	7	0
5220	4	242 1963 JOURNAL OF GENERAL PHYSIOLOGY 46(5):905-& JOBSIS FF SPECTROPHOTOMETRIC STUDIES ON INTACT MUSCLE .1. COMPONENTS OF RESPIRATORY CHAIN	49	7
5221	7	697 1967 JOURNAL OF GENERAL PHYSIOLOGY 50(4):1009-& JOBSIS FF; DUFFIELD JC OXIDATIVE AND GLYCOLYTIC RECOVERY METABOLISM IN MUSCLE - FLUOROMETRIC OBSERVATIONS ON THEIR RELATIVE CONTRIBUTIONS	97	13
5222	2	1649 1971 JOURNAL OF NEUROPHYSIOLOGY 34(5):735-& JOBSIS FF; OCONNOR M; VITALE A; VREMAN H INTRACELLULAR REDOX CHANGES IN FUNCTIONING CEREBRAL CORTEX .1. METABOLIC EFFECTS OF EPILEPTIFORM ACTIVITY	175	12
5223	5	938 1968 RESPIRATION PHYSIOLOGY 4(3):292-& JOBSIS FF; STAINSBY WN OXIDATION OF NADH DURING CONTRACTIONS OF CIRCULATED MAMMALIAN SKELETAL MUSCLE	177	6
5224	6	9334 1994 PHARMACOLOGY & TOXICOLOGY 75(1):7-16 JOCHMANN C; KLEE S; UNGEMACH FR; YOUNES M THE ROLE OF GLUTATHIONE AND PROTEIN THIOLS IN CBRCL3-INDUCED CYTOTOXICITY IN ISOLATED RAT HEPATOCYTES	2	0
5225	4	163 1962 BIOCHEMISTRY 1(2):281-& JOEL CD; BALL EG ELECTRON TRANSMITTER SYSTEM OF BROWN ADIPOSE TISSUE	37	5
5226	4	3476 1978 ANALYTICAL BIOCHEMISTRY 86(2):725-732 JOHANNESEN KAM; DEPIERRE JW MEASUREMENT OF CYTOCHROME-P-450 IN PRESENCE OF LARGE AMOUNTS OF CONTAMINATING HEMOGLOBIN AND METHEMOGLOBIN	181	34
5227	1	7006 1990 CONTRACEPTION 42(6):683-690 JOHANSEN RL; MISRA HP EFFECTS OF GOSSYPOL ON THE HEPATIC DRUG-METABOLIZING SYSTEM IN RATS	1	0
5228	11	6111 1988 BIOCHEMISTRY 27(6):1925-1934 JOHANSSON I; EKSTROM G; SCHOLTE B; PUZYCKI D; JORNVALL H; INGELMANSUNDBERG M ETHANOL-INDUCIBLE, FASTING-INDUCIBLE, AND ACETONE-INDUCIBLE CYTOCHROMES-P-450 IN RAT-LIVER - REGULATION AND CHARACTERISTICS OF ENZYMES BELONGING TO THE IIB-GENE AND IIE-GENE SUBFAMILIES	330	110
5229	6	4917 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258(12):7311-7316 JOHANSSON I; INGELMANSUNDBERG M HYDROXYL RADICAL-MEDIATED, CYTOCHROME-P-450-DEPENDENT METABOLIC-ACTIVATION OF BENZENE IN MICROSOMES AND RECONSTITUTED ENZYME-SYSTEMS FROM RABBIT LIVER	60	12
5230	17	8928 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 314(2):367-375 JOHN GH; HASLER JA; HE YA; HALPERT JR ESCHERICHIA-COLI EXPRESSION AND CHARACTERIZATION OF CYTOCHROMES P450 2B11, 2B1, AND 2B5	49	23
5231	4	5723 1986 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83(13):4715-4719 JOHN ME; JOHN MC; BOGGARAM V; SIMPSON ER; WATERMAN MR TRANSCRIPTIONAL REGULATION OF STEROID HYDROXYLASE GENES BY CORTICOTROPIN	217	70
5232	3	5942 1987 MOLECULAR AND CELLULAR ENDOCRINOLOGY 50(3):263-268 JOHN ME; SIMPSON ER; CARR BR; MAGNESS RR; ROSENFELD CR; WATERMAN MR; MASON JI ONTOGENY OF ADRENAL-STEROID HYDROXYLASES - EVIDENCE FOR CAMP- INDEPENDENT GENE-EXPRESSION	42	14
5233	9	5714 1986 MOLECULAR AND CELLULAR ENDOCRINOLOGY 45(2-3):197-204 JOHN ME; SIMPSON ER; WATERMAN MR; MASON JI REGULATION OF CHOLESTEROL SIDE-CHAIN CLEAVAGE CYTOCHROME-P-450 GENE-EXPRESSION IN ADRENAL-CELLS IN MONOLAYER-CULTURE	24	7
5234	1	3050 1976 CLINICAL PHARMACOLOGY & THERAPEUTICS 20(2):233-237 JOHNSEN SG; KAMPMANN JP; BENNETT EP; JORGENSEN FS ENZYME-INDUCTION BY ORAL TESTOSTERONE	27	2
5235	3	5394 1985 FEDERATION PROCEEDINGS 44(1):19-24 JOHNSON AR; REVTYAK G; CAMPBELL WB ARACHIDONIC-ACID METABOLITES AND ENDOTHELIAL INJURY - STUDIES WITH CULTURES OF HUMAN-ENDOTHELIAL CELLS	87	14
5236	5	6616 1989 INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY 11(2):217-227 JOHNSON BE; DIETERT RR; WASSOM DL THE RELATIVE IMPORTANCE OF AH VERSUS H-2 GENOTYPE ON TRICHINELLA RESISTANCE FOLLOWING EXPOSURE TO 3- METHYLCHOLANTHRENE	2	0
5237	2	631 1967 BIOCHEMISTRY 6(4):1121-& JOHNSON CL; MAURITZE.CM; STARBUCK WC; SCHWARTZ A HISTONES AND MITOCHONDRIAL ION TRANSPORT	33	2
5238	2	7975 1992 BIOLOGY OF REPRODUCTION 46(1):30-38 JOHNSON DC CELLULAR-LOCALIZATION AND FACTORS CONTROLLING RAT PLACENTAL CYTOCHROME P45017-ALPHA (CYP17) - 17-ALPHA-HYDROXYLASE/C17,20- LYASE ACTIVITY	11	1
5239	13	8346 1992 TRENDS IN PHARMACOLOGICAL SCIENCES 13(3):122-126 JOHNSON EF MAPPING DETERMINANTS OF THE SUBSTRATE SELECTIVITIES OF P450 ENZYMES BY SITE-DIRECTED MUTAGENESIS	50	30
5240	3	5914 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262(12):5918-5923 JOHNSON EF; BARNES HJ; GRIFFIN KJ; OKINO S; TUKEY RH CHARACTERIZATION OF A 2ND GENE-PRODUCT RELATED TO RABBIT CYTOCHROME-P-450-1	24	21
5241	5	6392 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 273(2):273-280 JOHNSON EF; FINLAYSON M; HUJSAK CM; PENDURTHI UR; TUKEY RH GENETIC CONTRIBUTIONS TO THE VARIATION AMONG RABBITS OF LIVER MICROSOMAL DEOXYCORTICOSTERONE SYNTHESIS	7	5
5242	18	8101 1992 FASEB JOURNAL 6(2):700-705 JOHNSON EF; KRONBACH T; HSU MH ANALYSIS OF THE CATALYTIC SPECIFICITY OF CYTOCHROME-P450 ENZYMES THROUGH SITE-DIRECTED MUTAGENESIS	32	24
5243	11	10196 1996 FASEB JOURNAL 10(11):1241-1248 Johnson EF; Palmer CNA; Griffin KJ; Hsu MH Cytochromes P450 .7. Role of the peroxisome proliferator- activated receptor in cytochrome P450 4A gene regulation	70	20
5244	4	6245 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(33):17672-17677 JOHNSON EF; SCHWAB GE; VICKERY LE POSITIVE EFFECTORS OF THE BINDING OF AN ACTIVE SITE-DIRECTED AMINO STEROID TO RABBIT CYTOCHROME-P-450-3C	50	22
5245	8	6909 1990 BIOCHEMISTRY 29(4):873-879 JOHNSON EF; WALKER DL; GRIFFIN KJ; CLARK JE; OKITA RT; MUERHOFF AS; MASTERS BS CLONING AND EXPRESSION OF 3 RABBIT KIDNEY CDNAS ENCODING LAURIC ACID OMEGA-HYDROXYLASES	59	43
5246	5	12791 2002 ENDOCRINE RESEARCH 28(4):435-441 Johnson EF; Wester MR; Stout CD The structure of microsomal cytochrome p450 2C5: A steroid and drug metabolizing enzyme	1	0
5247	2	2977 1976 BIOCHEMICAL GENETICS 14(5-6):403-426 JOHNSON GB POLYMORPHISM AND PREDICTABILITY AT ALPHA-GLYCEROPHOSPHATE DEHYDROGENASE LOCUS IN COLIAS BUTTERFLIES - GRADIENTS IN ALLELE FREQUENCY WITHIN SINGLE POPULATIONS	30	0
5248	7	2048 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):307-318 JOHNSON LR; RUHMANNW.A; NELSON DH IN-VIVO EFFECT OF ACTH ON UTILIZATION OF REDUCING ENERGY FOR PREGNENOLONE SYNTHESIS BY ADRENAL MITOCHONDRIA	44	11
5249	3	11838 1999 POSTGRADUATE MEDICINE 105(2):193-+ Johnson MD; Newkirk G; White JR Clinically significant drug interactions - What you need to know before writing prescriptions	15	4
5250	6	1494 1971 BIOCHEMICAL PHARMACOLOGY 20(5):955-& JOHNSON RK; MAZEL P; DONAHUE JD; JONDORF WR FACTORS INVOLVED IN INHIBITION OF DRUG METABOLISM BY (-)- EMETINE	5	1
5251	8	12961 2002 XENOBIOTICA 32(7):595-604 Johnson TN; Tanner MS; Tucker GT Developmental changes in the expression of enterocytic and hepatic cytochromes P4501A in rat	0	0
5252	2	10215 1996 HEPATOLOGY 24(3):677-684 Johnston DE; Kroening C Stimulation of prostaglandin synthesis in cultured liver cells by CCl4	11	1
5253	2	11374 1998 PHARMACOLOGY & TOXICOLOGY 83(6):231-239 Johnston DE; Kroening C Mechanism of early carbon tetrachloride toxicity in cultured rat hepatocytes	9	3
5254	7	6737 1989 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 35(2):107-118 JOHNSTON G; COLLETT G; WALKER C; DAWSON A; BOYD I; OSBORN D ENHANCEMENT OF MALATHION TOXICITY TO THE HYBRID RED-LEGGED PARTRIDGE FOLLOWING EXPOSURE TO PROCHLORAZ	24	2
5255	19	11152 1998 CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY 33(5):375-405 Johnston JO Aromatase inhibitors	5	0
5256	7	5118 1984 ENDOCRINOLOGY 115(2):776-785 JOHNSTON JO; WRIGHT CL; METCALF BW BIOCHEMICAL AND ENDOCRINE PROPERTIES OF A MECHANISM-BASED INHIBITOR OF AROMATASE	68	2
5257	6	12649 2001 TOXICOLOGY 166(3):139-160 Jokanovic M Biotransformation of organophosphorus compounds	1	0
5258	14	3230 1977 ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 1(1):17-20 JOLY JG; VILLENEUVE JP; MAVIER P CHRONIC ETHANOL ADMINISTRATION INDUCES A FORM OF CYTOCHROME-P- 450 WITH SPECIFIC SPECTRAL AND CATALYTIC PROPERTIES	49	9
5259	6	4348 1981 DRUG METABOLISM REVIEWS 12(2):379-430 JONDORF WR DRUG-METABOLIZING-ENZYMES AS EVOLUTIONARY PROBES	6	1
5260	13	2431 1974 BIOCHEMICAL PHARMACOLOGY 23(8):1319-1329 JONEN HG; HUTHWOHL B; KAHL R; KAHL GF INFLUENCE OF PYRIDINE AND SOME PYRIDINE-DERIVATIVES ON SPECTRAL PROPERTIES OF REDUCED MICROSOMES AND ON MICROSOMAL DRUG- METABOLIZING ACTIVITY	55	30
5261	0	2891 1975 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 287():R74-R74 JONEN HG; WERRINGLOER J; PROUGH RA; ESTABROOK RW DEGRADATION OF CYTOCHROME-P-450 BY PHENYLHYDRAZINE	3	3
5262	13	4650 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(8):4404-4411 JONEN HG; WERRINGLOER J; PROUGH RA; ESTABROOK RW THE REACTION OF PHENYLHYDRAZINE WITH MICROSOMAL CYTOCHROME-P- 450 - CATALYSIS OF HEME MODIFICATION	80	80
5263	2	7567 1991 EUROPEAN JOURNAL OF CANCER 27(3):301-301 JONES AL; DOWSETT MJ; POWLES TJ; GALLAGHER CJ; COOMBES RC TREATMENT OF ADVANCED BREAST-CANCER WITH MICONAZOLE - A POTENTIAL INHIBITOR OF PERIPHERAL ESTROGEN SYNTHESIS	0	0
5264	7	11176 1998 DRUG METABOLISM AND DISPOSITION 26(9):875-882 Jones BC; Hyland R; Ackland M; Tyman CA; Smith DA Interaction of terfenadine and its primary metabolites with cytochrome P450 2D6	9	3
5265	12	10933 1997 XENOBIOTICA 27(10):1025-1037 Jones BC; Tyman CA; Smith DA Identification of the cytochrome P450 isoforms involved in the O-demethylation of 4-nitroanisole in human liver microsomes	8	4
5266	8	12688 2002 ANTIOXIDANTS & REDOX SIGNALING 4(5):701-709 Jones BE; Liu HL; Lo CR; Koop DR; Czaja MJ Cytochrome P450 2E1 expression induces hepatocyte resistance to cell death from oxidative stress	0	0
5267	5	8868 1993 TOXICOLOGY IN VITRO 7(6):685-& JONES C; GREINER B; WACHTER F; TERLOUW GDC; BECHTER R AN IMMUNOHISTOCHEMICAL INVESTIGATION INTO THE PRESENCE AND LOCALIZATION OF CYTOCHROME-P-450 ISOZYMES IN ORGANOGENESIS- STAGE RAT CONCEPTAL TISSUE	0	0
5268	11	10516 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 347(2):163-173 Jones CL; Reiners JJ Differentiation status of cultured murine keratinocytes modulates induction of genes responsive to 2,3,7,8- tetrachlorodibenzo-p-dioxin	6	1
5269	2	649 1967 BIOCHIMICA ET BIOPHYSICA ACTA 143(2):340-& JONES CW; REDFEARN ER CYTOCHROME SYSTEM OF AZOTOBACTER VINELANDII	116	6
5270	3	5532 1986 ANNUAL REVIEW OF PHYSIOLOGY 48():33-50 JONES DP RENAL METABOLISM DURING NORMOXIA, HYPOXIA, AND ISCHEMIC-INJURY	47	0
5271	7	4257 1981 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 210(2):505-516 JONES DP; EKLOW L; THOR H; ORRENIUS S METABOLISM OF HYDROGEN-PEROXIDE IN ISOLATED HEPATOCYTES - RELATIVE CONTRIBUTIONS OF CATALASE AND GLUTATHIONE-PEROXIDASE IN DECOMPOSITION OF ENDOGENOUSLY GENERATED H2O2	195	15
5272	9	4134 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(6):2383-2390 JONES DP; GRAFSTROM R; ORRENIUS S QUANTITATION OF HEMOPROTEINS IN RAT SMALL INTESTINAL-MUCOSA WITH IDENTIFICATION OF MITOCHONDRIAL CYTOCHROME-P-450	29	3
5273	12	3631 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253(14):4874-4880 JONES DP; MASON HS GRADIENTS OF O2 CONCENTRATION IN HEPATOCYTES	155	11
5274	2	3771 1979 BIOCHEMICAL PHARMACOLOGY 28(6):929-935 JONES DP; SUNDBY GB; ORMSTAD K; ORRENIUS S USE OF ISOLATED KIDNEY-CELLS FOR STUDY OF DRUG-METABOLISM	140	8
5275	6	10267 1996 JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS 678(1):105-111 Jones DR; Gorski JC; Hamman MA; Hall SD Quantification of dextromethorphan and metabolites: A dual phenotypic marker for cytochrome P450 3A4/5 and 2D6 activity	24	3
5276	1	616 1967 BIOCHEMICAL JOURNAL 103(2):420-& JONES EA CHANGES IN ENZYME PATTERN OF MAMMARY GLAND OF LACTATING RAT AFTER HYPOPHYSECTOMY AND WEANING	34	0
5277	19	10448 1996 XENOBIOTICA 26(10):995-1012 Jones EJ; Riddick DS Regulation of constitutive rat hepatic cytochromes P450 by 3- methylcholanthrene	13	2
5278	2	5390 1985 EXPERIENTIA 41(8):1045-1046 JONES GRN; THATCHER R A COMPARISON OF THE EFFECTS OF THE OPTICAL ISOMERS OF ISOPROTERENOL ON ENERGY-METABOLISM IN A MOUSE SARCOMA	2	0
5279	6	6551 1989 DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY 8(7):527-534 JONES JE; NEBERT DW TRANSCRIPTIONAL START SITE IN THE MOUSE CYP1A1 (CYTOCHROME- P1450) GENE	1	1
5280	10	10137 1996 DESIGNING SAFER CHEMICALS 640():116-137 Jones JP Predicting rates of cytochrome-P450-mediated bioactivation and its application to the design of safer chemicals	0	0
5281	5	7175 1990 JOURNAL OF MEDICINAL CHEMISTRY 33(4):1242-1246 JONES JP; RETTIE AE; TRAGER WF INTRINSIC ISOTOPE EFFECTS SUGGEST THAT THE REACTION COORDINATE SYMMETRY FOR THE CYTOCHROME-P-450 CATALYZED HYDROXYLATION OF OCTANE IS ISOZYME INDEPENDENT	41	9
5282	1	617 1967 BIOCHEMICAL JOURNAL 103(3):714-& JONES RGW UBIQUINONE DEFICIENCY IN AN AUXOTROPH OF ESCHERICHIA COLI REQUIRING 4-HYDROXYBENZOIC ACID	13	0
5283	5	7913 1992 BIOCHEMICAL PHARMACOLOGY 43(8):1876-1879 JONES SM; BOOBIS AR; MOORE GE; STANIER PM EXPRESSION OF CYP2E1 DURING HUMAN FETAL DEVELOPMENT - METHYLATION OF THE CYP2E1 GENE IN HUMAN FETAL AND ADULT LIVER SAMPLES	28	13
5284	4	4570 1982 BIOSYSTEMS 15(1):49-58 JONNALAGADDA SB; BECKER JU; SELKOV EE; BETZ A FLUX REGULATION IN GLYCOGEN-INDUCED OSCILLATORY GLYCOLYSIS IN CELL-FREE-EXTRACTS OF SACCHAROMYCES-CARLSBERGENSIS	6	1
5285	10	3227 1977 ACTA PHARMACOLOGICA ET TOXICOLOGICA 40(4):517-528 JONSSON J AROMATIC HYDROXYLATION OF AMPHETAMINE IN RAT-LIVER MICROSOMES AND PERFUSED LIVER PREPARATIONS - EFFECTS OF LONG-TERM ADMINISTRATION	12	1
5286	10	2937 1976 ACTA PHARMACEUTICA SUECICA 13(4):313-320 JONSSON J; LINDEKE B FORMATION OF CYTOCHROME-P-450 PRODUCT COMPLEXES DURING METABOLISM OF PHENYLALKYLAMINES	58	23
5287	2	2644 1975 ACTA PHARMACOLOGICA ET TOXICOLOGICA 37(5):352-360 JONSSON J; LINDEKE B; CHO AK OXIDATION OF PHENETHYLAMINE YIELDING TYRAMINE BY RAT-LIVER MICROSOMES	8	2
5288	6	2446 1974 BIOCHEMICAL PHARMACOLOGY 23(22):3191-3197 JONSSON JA HYDROXYLATION OF AMPHETAMINE TO PARAHYDROXYAMPHETAMINE BY RAT- LIVER MICROSOMES	35	5
5289	5	11578 1999 CHEMISTRY & BIOLOGY 6(10):699-706 Joo H; Arisawa A; Lin ZL; Arnold FH A high-throughput digital imaging screen for the discovery and directed evolution of oxygenases	27	3
5290	7	11805 1999 NATURE 399(6737):670-673 Joo H; Lin ZL; Arnold FH Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation	99	20
5291	4	4537 1982 BIOCHEMICAL PHARMACOLOGY 31(7):1393-1400 JORDAN RA; SCHENKMAN JB RELATIONSHIP BETWEEN MALONDIALDEHYDE PRODUCTION AND ARACHIDONATE CONSUMPTION DURING NADPH-SUPPORTED MICROSOMAL LIPID-PEROXIDATION	55	8
5292	10	9668 1995 FEBS LETTERS 365(2-3):101-107 JORGENSEN ECB; AUTRUP H EFFECT OF A NEGATIVE REGULATORY ELEMENT (NRE) ON THE HUMAN CYP1A1 GENE-EXPRESSION IN BREAST-CARCINOMA MCF-7 AND HEPATOMA HEPG2 CELLS	10	3
5293	16	10090 1996 CARCINOGENESIS 17(3):435-441 Jorgensen ECB; Autrup H Autoregulation of human CYP1A1 gene promotor activity in HepG2 and MCF-7 cells	16	2
5294	13	4738 1983 ACTA PHARMACOLOGICA ET TOXICOLOGICA 53(1):70-77 JORGENSEN L; JOHANSEN T AFFINITY OF DRUGS FOR CYTOCHROME-P-450 DETERMINED BY INHIBITION OF PARA-NITROPHENETOLE O-DEETHYLATION BY RAT-LIVER MICROSOMES	4	0
5295	3	2480 1974 CHEMICO-BIOLOGICAL INTERACTIONS 8(5):297-302 JORI A; PESCADOR R STRAIN DIFFERENCES IN INDUCTION OF SOLUBLE AND MICROSOMAL- ENZYMES BYPHENOBARBITAL AND 3-METHYLCHOLANTHRENE	14	3
5296	1	1514 1971 BIOCHEMICAL PHARMACOLOGY 20(10):2695-& JORI A; PESCADOR R; PUGLIATT.C RAT STRAIN DIFFERENCES IN ACTIVITY OF HEPATIC MICROSOMAL ENZYMES	16	4
5297	1	11667 1999 FEBS LETTERS 456(1):85-88 Jornvall H Motifer, a search tool for finding amino acid sequence patterns from nucleotide sequence databases	0	0
5298	8	12857 2002 JOURNAL OF BIOTECHNOLOGY 95(3):257-268 Jose J; Bernhardt R; Hannemann F Cellular surface display of dimeric Adx and whole cell P450- mediated steroid synthesis on E-coli	2	0
5299	4	11672 1999 FERTILITY AND STERILITY 71(3):528-535 Jose M; Puche C; Cabero A; Cabero L; Meseguer A Expression of P450c17 messenger ribonucleic acid in postmenopausal human ovary tissues	5	0
5300	7	2371 1973 XENOBIOTICA 3(6):357-366 JOSE PJ; SLATER TF STIMULATION OF LIPID PEROXIDATION PRODUCED BY DIMETHYLNITROSAMINE IN RAT-LIVER MICROSOMES IN-VITRO - EFFECTS OF PROMETHAZINE AND INHIBITORS OF DRUG-METABOLISM, AND A COMPARISON WITH PREVIOUS STUDIES USING CARBON-TETRACHLORIDE	14	2

#	Cited nodes	Nodes / Authors	GCS	LCS
5301	7	5190 1984 JOURNAL OF PHARMACY AND PHARMACOLOGY 36(10):711-712 JOSEPH CA; DIXON PAF A POSSIBLE CYTOCHROME-P-450-MEDIATED N-OXIDATION OF DIETHYLCARBAMAZINE	2	0
5302	17	12996 2003 BIOCHEMICAL PHARMACOLOGY 65(11):1817-1826 Joseph S; Rusling JF; Lvov YM; Friedberg T; Fuhr U An amperometric biosensor with human CYP3A4 as a novel drug screening tool	0	0
5303	3	9670 1995 FEBS LETTERS 374(2):174-178 JOSEPHHORNE T; HOLLOMON D; LOEFFLER RST; KELLY SL ALTERED P450 ACTIVITY ASSOCIATED WITH DIRECT SELECTION FOR FUNGAL AZOLE RESISTANCE	29	4
5304	8	12953 2002 TOXICOLOGY 181():255-260 Josephy PD Genetically-engineered bacteria expressing human enzymes and their use in the study of mutagens and mutagenesis	0	0
5305	19	12466 2001 ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 38(1):12-18 Josephy PD; Batty SM; Boverhof DR Recombinant human P450 forms 1A1, 1A2, and 1B1 catalyze the bioactivation of heterocyclic amine mutagens in Escherichia coli lacZ strains	2	1
5306	13	10842 1997 MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH 386(1):1-23 Josephy PD; Gruz P; Nohmi T Recent advances in the construction of bacterial genotoxicity assays	30	7
5307	3	11357 1998 PHARMACEUTICAL RESEARCH 15(8):1189-1195 Joshi R; Arora V; Desjardins JP; Robinson D; Himmelstein KJ; Iversen PL In vivo properties of an in situ forming gel for parenteral delivery of macromolecular drugs	6	1
5308	18	8956 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 205(3):1741-1747 JOUNAIDI Y; GUZELIAN PS; MAUREL P; VILAREM MJ SEQUENCE OF THE 5'-FLANKING REGION OF CYP3A5 - COMPARATIVE- ANALYSIS WITH CYP3A4 AND CYP3A7	34	22
5309	13	11099 1998 CANCER RESEARCH 58(19):4391-4401 Jounaidi Y; Hecht JED; Waxman DJ Retroviral transfer of human cytochrome P450 genes for oxazaphosphorine-based cancer gene therapy	31	7
5310	13	10004 1996 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 221(2):466-470 Jounaidi Y; Hyrailles V; Gervot L; Maurel P Detection of a CYP3A5 allelic variant: A candidate for the polymorphic expression of the protein?	35	19
5311	4	5092 1984 CANADIAN JOURNAL OF BIOCHEMISTRY AND CELL BIOLOGY 62(10):935-944 JOUVE HM; GAILLARD J; PELMONT J CHARACTERIZATION AND SPECTRAL PROPERTIES OF PROTEUS-MIRABILIS PR CATALASE	16	0
5312	6	11222 1998 FEBS LETTERS 431(2):227-230 Jover R; Bort R; Gomez-Lechon MJ; Castell JV Re-expression of C/EBP alpha induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cells	16	3
5313	7	10009 1996 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 226(1):152-157 Jover R; Hoffmann K; Meyer UA Induction of 5-aminolevulinate synthase by drugs is independent of increased apocytochrome P450 synthesis	13	3
5314	7	10355 1996 MOLECULAR PHARMACOLOGY 50(3):474-481 Jover R; Lindberg RLP; Meyer UA Role of heme in cytochrome P450 transcription and function in mice treated with lead acetate	11	4
5315	8	7541 1991 EMBO JOURNAL 10(5):1075-1081 JOWETT T; WAJIDI MFF; OXTOBY E; WOLF CR MAMMALIAN GENES EXPRESSED IN DROSOPHILA - A TRANSGENIC MODEL FOR THE STUDY OF MECHANISMS OF CHEMICAL MUTAGENESIS AND METABOLISM	25	6
5316	2	7273 1990 PLANTA MEDICA 56(2):171-174 JOYEUX M; ROLLAND A; FLEURENTIN J; MORTIER F; DORFMAN P TERT-BUTYL HYDROPEROXIDE-INDUCED INJURY IN ISOLATED RAT HEPATOCYTES - A MODEL FOR STUDYING ANTIHEPATOTOXIC CRUDE DRUGS	35	1
5317	1	5045 1984 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 120(2):548-552 JUBIZ W; NOLAN G A PREVIOUSLY UNIDENTIFIED LEUKOTRIENE PRODUCED BY HUMAN POLYMORPHONUCLEAR LEUKOCYTES	3	0
5318	3	6361 1989 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 29():165-187 JUCHAU MR BIOACTIVATION IN CHEMICAL TERATOGENESIS	43	10
5319	25	7207 1990 LIFE SCIENCES 47(26):2385-2394 JUCHAU MR SUBSTRATE SPECIFICITIES AND FUNCTIONS OF THE P450 CYTOCHROMES	57	25
5320	28	11183 1998 DRUG METABOLISM REVIEWS 30(3):541-568 Juchau MR; Boutelet-Bochan H; Huang Y Cytochrome-P450-dependent biotransformation of xenobiotics in human and rodent embryonic tissues	19	4
5321	4	1991 1972 PEDIATRIC CLINICS OF NORTH AMERICA 19(1):65-& JUCHAU MR; DYER DC PHARMACOLOGY OF PLACENTA	19	3
5322	32	8064 1992 DRUG METABOLISM REVIEWS 24(2):195-238 JUCHAU MR; LEE QP; FANTEL AG XENOBIOTIC BIOTRANSFORMATION BIOACTIVATION IN ORGANOGENESIS- STAGE CONCEPTUAL TISSUES - IMPLICATIONS FOR EMBRYOTOXICITY AND TERATOGENESIS	64	12
5323	1	741 1968 AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 100(3):348-& JUCHAU MR; NISWANDE.KR; YAFFE SJ DRUG METABOLIZING SYSTEMS IN HOMOGENATES OF HUMAN IMMATURE PLACENTAS	35	6
5324	4	1794 1972 BIOCHEMICAL PHARMACOLOGY 21(15):2053-& JUCHAU MR; SYMMS KG ANILINE HYDROXYLATION IN HUMAN PLACENTA - MECHANISTIC ASPECTS	52	8
5325	8	2697 1975 BIOCHEMICAL PHARMACOLOGY 24(12):227-233 JUCHAU MR; ZACHARIAH PK COMPARATIVE STUDIES ON OXIDATION AND REDUCTION OF DRUG SUBSTRATES IN HUMAN PLACENTAL VERSUS RAT HEPATIC MICROSOMES	29	7
5326	1	6253 1988 JOURNAL OF MAGNETIC RESONANCE 76(1):178-182 JUE T; CHUNG Y; SHULMAN RG MEASURING THE REDOX POTENTIAL IN PERFUSED LIVER WITH H-1-NMR	11	0
5327	5	5882 1987 DRUG METABOLISM AND DISPOSITION 15(6):786-793 JUEDES MJ; BULGER WH; KUPFER D MONOOXYGENASE-MEDIATED ACTIVATION OF CHLOROTRIANISENE (TACE) IN COVALENT BINDING TO RAT HEPATIC-MICROSOMAL PROTEINS	7	4
5328	8	9228 1994 JOURNAL OF INVESTIGATIVE DERMATOLOGY 102(6):970-975 JUGERT FK; AGARWAL R; KUHN A; BICKERS DR; MERK HF; MUKHTAR H MULTIPLE CYTOCHROME-P450 ISOZYMES IN MURINE SKIN - INDUCTION OF P450 1A, 2B, 2E, AND 3A BY DEXAMETHASONE	40	5
5329	10	8032 1992 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 102(4):747-755 JULISTIONO H; BRIAND J MICROSOMAL ETHANOL-OXIDIZING SYSTEM IN EUGLENA-GRACILIS - SIMILARITIES BETWEEN EUGLENA AND MAMMALIAN-CELL SYSTEMS	6	1
5330	13	5333 1985 BIOLOGICAL CHEMISTRY HOPPE-SEYLER 366(1):23-31 JUNG B; GRAF H; ULLRICH V A NEW MONOOXYGENASE PRODUCT FROM 7-ETHOXYCOUMARIN AND ITS RELATION TO THE O-DEALKYLATION REACTION	6	3
5331	5	9659 1995 EUROPEAN JOURNAL OF BIOCHEMISTRY 233(2):600-606 JUNG C; HOA GHB; DAVYDOV D; GILL E; HEREMANS K COMPRESSIBILITY OF THE HEME POCKET OF SUBSTRATE-ANALOG COMPLEXES OF CYTOCHROME P-450CAM-CO - THE EFFECT OF HYDROSTATIC-PRESSURE ON THE SORET BAND	17	5
5332	3	7944 1992 BIOCHEMISTRY 31(51):12855-12862 JUNG C; HOA GHB; SCHRODER KL; SIMON M; DOUCET JP SUBSTRATE-ANALOG INDUCED CHANGES OF THE CO-STRETCHING MODE IN THE CYTOCHROME-P450CAM-CARBON MONOXIDE COMPLEX	60	20
5333	7	7450 1991 BIOCHIMICA ET BIOPHYSICA ACTA 1076(1):130-136 JUNG C; RISTAU O; REIN H THE HIGH-SPIN LOW-SPIN EQUILIBRIUM IN CYTOCHROME-P-450 - A NEW METHOD FOR DETERMINATION OF THE HIGH-SPIN CONTENT	27	13
5334	3	10176 1996 EUROPEAN JOURNAL OF BIOCHEMISTRY 235(3):660-669 Jung C; Ristau O; Schulze H; Sligar SG The CO stretching mode infrared spectrum of substrate-free cytochrome P-450(cam)-CO - The effect of solvent conditions, temperature, and pressure	20	8
5335	6	10046 1996 BIOCHEMISTRY 35(47):15088-15094 Jung C; Schulze H; Deprez E Role of the polarity of the heme environment for the CO stretch modes in cytochrome P-450cam-CO	14	4
5336	5	10537 1997 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 239(2):457-462 Jung CH; Wells WW Ascorbic acid is a stimulatory cofactor for mitochondrial glycerol-3-phosphate dehydrogenase	6	1
5337	1	5293 1985 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 130(2):559-566 JUNG G; YANG DC; NAKAO A OXYGENATION OF PHOSPHATIDYLCHOLINE BY HUMAN POLYMORPHONUCLEAR LEUKOCYTE 15-LIPOXYGENASE	44	4
5338	3	12311 2001 APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 55(2):187-191 Jung Y; Kwak J; Lee Y High-level production of heme-containing holoproteins in Escherichia coli	1	1
5339	6	2678 1975 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 171(2):398-406 JUNGE O; BRAND K MIXED-FUNCTION OXIDATION OF HEXOBARBITAL AND GENERATION OF NADPH BY HEXOSE MONOPHOSPHATE SHUNT IN ISOLATED RAT-LIVER CELLS	44	0
5340	9	7042 1990 ENDOCRINOLOGY 126(3):1534-1540 JUNIER MP; DRAY F; BLAIR I; CAPDEVILA J; DISHMAN E; FALCK JR; OJEDA SR EPOXYGENASE PRODUCTS OF ARACHIDONIC-ACID ARE ENDOGENOUS CONSTITUENTS OF THE HYPOTHALAMUS INVOLVED IN D2 RECEPTOR- MEDIATED, DOPAMINE-INDUCED RELEASE OF SOMATOSTATIN	39	11
5341	4	9566 1995 CELL BIOLOGY AND TOXICOLOGY 11(6):313-327 JurimaRomet M; Casley WL; Neu JM; Huang HS Induction of CYP3A and associated terfenadine N-dealkylation in rat hepatocytes cocultured with 3T3 cells	7	1
5342	4	8482 1993 BIOCHEMICAL PHARMACOLOGY 46(12):2163-2170 JURIMAROMET M; HUANG HS COMPARATIVE CYTOTOXICITY OF ANGIOTENSIN-CONVERTING ENZYME- INHIBITORS IN CULTURED RAT HEPATOCYTES	10	2
5343	5	10429 1996 TOXICOLOGY IN VITRO 10(6):655-663 JurimaRomet M; Huang HS; Beck DJ; Li AP Evaluation of drug interactions in intact hepatocytes: Inhibitors of terfenadine metabolism	6	1
5344	3	2404 1974 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 165(1):98-113 JURKOWIT.M; SCOTT KM; ALTSCHUL.RA; MEROLA AJ; BRIERLEY GP ION-TRANSPORT BY HEART-MITOCHONDRIA .28. RETENTION AND LOSS OF ENERGY COUPLING IN AGED HEART-MITOCHONDRIA	53	0
5345	1	677 1967 JOURNAL OF BACTERIOLOGY 93(3):1069-& JURTSHUK P; ASTON PR; OLD L ENZYMATIC OXIDATION OF TETRAMETHYL-P-PHENYLENEDIAMINE AND P- PHENYLENEDIAMINE BY ELECTRON TRANSPORT PARTICULATE FRACTION OF AZOTOBACTER VINELANDII	40	3
5346	2	1051 1969 CANADIAN JOURNAL OF MICROBIOLOGY 15(7):797-& JURTSHUK P; MAY AK; POPE LM; ASTON PR COMPARATIVE STUDIES ON SUCCINATE AND TERMINAL OXIDASE ACTIVITY IN MICROBIAL AND MAMMALIAN ELECTRON-TRANSPORT SYSTEMS	25	1
5347	6	3821 1979 CURRENT MICROBIOLOGY 2(6):349-354 JURTSHUK P; MCQUITTY DN; RILEY WH USE OF 3,3'-DIAMINOBENZIDINE AS A BIOCHEMICAL ELECTRON-DONOR FOR STUDIES ON TERMINAL CYTOCHROME-OXIDASE ACTIVITY IN AZOTOBACTER-VINELANDII	6	1
5348	3	5656 1986 FEMS MICROBIOLOGY LETTERS 37(1):15-18 JUSSOFIE A; GOTTSCHALK G FURTHER-STUDIES ON THE DISTRIBUTION OF CYTOCHROMES IN METHANOGENIC BACTERIA	23	1
5349	1	737 1968 ACTA PHYSIOLOGICA SCANDINAVICA S():2-& JUVA K HYDROXYLATION OF PROLINE IN BIOSYNTHESIS OF COLLAGEN - AN EXPERIMENTAL STUDY WITH CHICK EMBRYO AND GRANULATION TISSUE OF RAT	0	0
5350	4	3613 1978 INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY 16(2):263-264 KACHOLE MS; MAKHIJA SJ; PAWAR SS; SATHE CH MICROSOMAL MIXED-FUNCTION OXIDASE SYSTEM IN HUMAN PLACENTA - SUBSTRATE INTERACTIONS WITH CYTOCHROME-P-450	0	0
5351	2	2805 1975 EXPERIMENTAL NEUROLOGY 46(1):57-68 KACZMAREK LK; ADEY WR CORTICAL RELEASE OF LABELED COMPOUNDS DURING AROUSAL IN CAT - CORRELATIONS WITH CARBON-DIOXIDE, BRAIN TEMPERATURE AND EEG	2	0
5352	12	8231 1992 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 42(5):499-508 KADDOURI M; BRASSET N; ALVINERIE M; EECKHOUTTE C; BONFILS C; DERANCOURT J; GALTIER P ONTOGENIC DEVELOPMENT OF LIVER PROGESTERONE METABOLISM IN FEMALE SHEEP - CONTRIBUTION OF CYTOCHROME-P4502B AND P4503A- SUBFAMILIES	19	8
5353	4	943 1968 ZEITSCHRIFT FUR ANALYTISCHE CHEMIE FRESENIUS 243(DEC):542-& KADENBAC.B; URBAN PF APPLICATION OF A QUANTITATIVE CHROMATOGRAPHIC METHOD OF PURIFICATION IN STUDY OF BIOSYNTHESIS OF CYTOCHROME C	11	0
5354	1	442 1965 STEROIDS 5(3):319-& KADIS B EPOXIDATION OF PREGN-4 16-DIENE-3 20-DIONE BY SOW OVARY	6	0
5355	2	551 1966 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 88(8):1846-& KADIS B STEROID HYDROXYLATIONS .3. ROLE OF REDUCED NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE (NADPH)	5	2
5356	6	2395 1974 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 162(1):83-92 KADLUBAR FF; ZIEGLER DM PROPERTIES OF A NADH-DEPENDENT N-HYDROXY AMINE REDUCTASE ISOLATED FROM PIG LIVER-MICROSOMES	55	19
5357	5	2367 1973 VOPROSY MEDITSINSKOI KHIMII 19(3):227-241 KAGAN VE; KOTELEVT.SV; SITKOVSK.MV; DANILOV VS; KOZLOV YP PEROXIDE OXIDATION OF LIPIDS IN MICROSOMES	6	0
5358	3	3791 1979 BIOCHEMISTRY-MOSCOW 44(3):379-385 KAGAN VE; PRILIPKO LL; SAVOV VM; PISAREV VA; ELUASHVILI IA; KOZLOV YP PARTICIPATION OF FREE ACTIVE FORMS OF OXYGEN IN ENZYMATIC PEROXIDATION OF LIPIDS IN BIOMEMBRANES	1	0
5359	11	11625 1999 DRUG METABOLISM REVIEWS 31(2):333-342 Kagawa N; Bischof LJ; Cheng PY; Anwar A; Waterman MR Biochemical diversity of peptide-hormone-dependent regulation of steroidogenic P450s	3	0
5360	34	12242 2000 SEIBUTSU-KOGAKU KAISHI 78(3):82-93 Kagawa N; Kusano K; Nonaka Y Heterologous expression of mammalian cytochrome P450 as active forms in Escherichia coli - Review	2	0
5361	7	9199 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(29):18716-18719 KAGAWA N; OGO A; TAKAHASHI Y; IWAMATSU A; WATERMAN MR A CAMP-REGULATORY SEQUENCE (CRS1) OF CYP17 IS A CELLULAR TARGET FOR THE HOMEODOMAIN PROTEIN PBX1	47	12
5362	6	7140 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(19):11299-11305 KAGAWA N; WATERMAN MR CAMP-DEPENDENT TRANSCRIPTION OF THE HUMAN CYP21B (P-450C21) GENE REQUIRES A CIS-REGULATORY ELEMENT DISTINCT FROM THE CONSENSUS CAMP-REGULATORY ELEMENT	70	20
5363	6	7627 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(17):11199-11204 KAGAWA N; WATERMAN MR EVIDENCE THAT AN ADRENAL-SPECIFIC NUCLEAR-PROTEIN REGULATES THE CAMP RESPONSIVENESS OF THE HUMAN CYP21B (P450C21) GENE	43	15
5364	6	6056 1988 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 155(1):379-383 KAGIMOTO K; MCCARTHY JL; WATERMAN MR; KAGIMOTO M DEDUCED AMINO-ACID SEQUENCE OF MATURE CHICKEN TESTIS FERREDOXIN	19	5
5365	2	6611 1989 HUMAN GENETICS 82(3):285-286 KAGIMOTO K; WATERMAN MR; KAGIMOTO M; FERREIRA P; SIMPSON ER; WINTER JSD IDENTIFICATION OF A COMMON MOLECULAR-BASIS FOR COMBINED 17- ALPHA-HYDROXYLASE 17,20-LYASE DEFICIENCY IN 2 MENNONITE FAMILIES	28	11
5366	7	7146 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(28):17209-17214 KAGIMOTO M; HEIM M; KAGIMOTO K; ZEUGIN T; MEYER UA MULTIPLE MUTATIONS OF THE HUMAN CYTOCHROME-P450IID6 GENE (CYP2D6) IN POOR METABOLIZERS OF DEBRISOQUINE - STUDY OF THE FUNCTIONAL-SIGNIFICANCE OF INDIVIDUAL MUTATIONS BY EXPRESSION OF CHIMERIC GENES	175	42
5367	8	6232 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(18):8925-8928 KAGIMOTO M; KAGIMOTO K; SIMPSON ER; WATERMAN MR TRANSCRIPTION OF THE BOVINE ADRENODOXIN GENE PRODUCES 2 SPECIES OF MESSENGER-RNA OF WHICH ONLY ONE IS TRANSLATED INTO ADRENODOXIN	11	3
5368	2	6277 1988 MOLECULAR ENDOCRINOLOGY 2(6):564-570 KAGIMOTO M; WINTER JSD; KAGIMOTO K; SIMPSON ER; WATERMAN MR STRUCTURAL CHARACTERIZATION OF NORMAL AND MUTANT HUMAN STEROID 17-ALPHA-HYDROXYLASE GENES - MOLECULAR-BASIS OF ONE EXAMPLE OF COMBINED 17-ALPHA-HYDROXYLASE/17,20 LYASE DEFICIENCY	75	32
5369	9	1392 1970 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 266(1):61-& KAHL GF EXPERIMENTS ON METYRAPONE REDUCING MICROSOMAL ENZYME SYSTEM	36	5
5370	18	1660 1971 KLINISCHE WOCHENSCHRIFT 49(7):384-& KAHL GF MODIFICATIONS OF RATE OF DRUG METABOLISATION AND THEIR SIGNIFICANCE IN PHARMACOTHERAPY	29	2
5371	15	3133 1976 JOURNAL OF BIOLOGICAL CHEMISTRY 251(17):5397-5407 KAHL GF; KAHL R; KUMAKI K; NEBERT DW ASSOCIATION OF AH LOCUS WITH SPECIFIC CHANGES IN METYRAPONE AND ETHYLISOCYANIDE BINDING TO MOUSE-LIVER MICROSOMES	20	8
5372	3	2202 1973 DRUG METABOLISM AND DISPOSITION 1(1):191-193 KAHL GF; MINCK K; NETTER KJ ENHANCEMENT OF TYPE II SUBSTRATE OXIDATION AND OF AZO REDUCTION IN ISOLATED RAT-LIVER AND IN-VITRO BY METYRAPONE	12	9
5373	6	1227 1970 BIOCHEMICAL PHARMACOLOGY 19(1):27-& KAHL GF; NETTER KJ EFFECT OF METYRAPONE ON CELLULAR RESPIRATION AND MICROSOMAL DRUG OXIDATION	10	8
5374	6	1681 1971 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 268(1):1-& KAHL GF; SIMON S ACTION OF METYRAPONE ON REDOX STATE OF FREE NICOTINAMIDE- ADENINE DINUCLEOTIDE AND ON OXYGEN CONSUMPTION OF PERFUSED RAT LIVERS AND ISOLATED MITOCHONDRIA	3	2
5375	4	6766 1989 TOXICOLOGY 59(2):179-194 KAHL R; WEINKE S; KAPPUS H PRODUCTION OF REACTIVE OXYGEN SPECIES DUE TO METABOLIC- ACTIVATION OF BUTYLATED HYDROXYANISOLE	37	3
5376	11	10260 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(51):32944-32950 Kahn RA; Bak S; Olsen CE; Svendsen I; Moller BL Isolation and reconstitution of the heme-thiolate protein obtusifoliol 14 alpha-demethylase from Sorghum bicolor (L.) Moench	17	6
5377	5	1712 1972 ACTA ENDOCRINOLOGICA 70(2):315-& KAHNT FW; NEHER R ADRENOCORTICAL STEROID BIOSYNTHESIS IN-VITRO - PART .5. ACTIVATORS AND INHIBITORS - EVIDENCE FOR PRESENCE OF SUBSTRATE- SPECIFIC 21-HYDROXYLASES	26	7
5378	5	5097 1984 CHEMICAL & PHARMACEUTICAL BULLETIN 32(10):4017-4022 KAI M; NOGUCHI S; BABA H; OHKURA Y SENSITIVE FLUORIMETRIC ASSAY FOR HUMAN THYROID PEROXIDASE USING PARA-CRESOL AS A SUBSTRATE	1	0
5379	2	1334 1970 JOURNAL OF BIOCHEMISTRY 68(2):177-& KAKINUMA K METABOLIC CONTROL AND INTRACELLULAR PH DURING PHAGOCYTOSIS BY POLYMORPHONUCLEAR LEUCOCYTES	35	0
5380	1	1204 1970 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 140(2):334-& KAKLIJ GS; NADKARNI GB ADAPTIVE ALTERATIONS IN LACTOBACILLUS-CASEI .2. VARIATION IN LEVELS OF ALDOLASE IN CELLS GROWN ON GLUCOSE AND RIBOSE	19	0
5381	2	1048 1969 CANADIAN JOURNAL OF BIOCHEMISTRY 47(6):611-& KAKO KJ ADP-DEPENDENT PALMITOYLCARNITINE SENSITIVITY OF MITOCHONDRIA ISOLATED FROM PERFUSED RABBIT HEART	10	0
5382	2	11782 1999 MEDICAL SCIENCE RESEARCH 27(9):617-620 Kalapos MP Influence of acetone on the hepatotoxicity of methylglyoxal	1	0
5383	5	7457 1991 BIOCHIMICA ET BIOPHYSICA ACTA 1092(3):284-290 KALAPOS MP; GARZO T; ANTONI F; MANDL J EFFECT OF METHYLGLYOXAL ON GLUCOSE FORMATION, DRUG OXIDATION AND GLUTATHIONE CONTENT IN ISOLATED MURINE HEPATOCYTES	17	3
5384	3	9163 1994 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 26(9):1069-1079 KALAPOS MP; MANDL J; BANHEGYI G; ANTONI F; GARZO T NET GLUCOSE-PRODUCTION FROM ACETONE IN ISOLATED MURINE HEPATOCYTES - THE EFFECT OF DIFFERENT PRETREATMENTS OF MICE	6	1
5385	5	10185 1996 EXPERIENTIA 52(8):827-830 Kalapos MP; Riba P; Garzo T; Mandl J Glucose formation from methylglyoxal in hepatocytes from streptozotocin-induced diabetic mice: The effect of insulin	3	0
5386	6	7795 1991 TOXICOLOGY LETTERS 58(2):181-191 KALAPOS MP; SCHAFF Z; GARZO T; ANTONI F; MANDL J ACCUMULATION OF PHENOLS IN ISOLATED HEPATOCYTES AFTER PRETREATMENT WITH METHYLGLYOXAL	12	2
5387	8	6306 1988 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85(19):7221-7225 KALB VF; LOPER JC PROTEINS FROM EIGHT EUKARYOTIC CYTOCHROME-P-450 FAMILIES SHARE A SEGMENTED REGION OF SEQUENCE SIMILARITY	65	37
5388	5	5874 1987 DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY 6(6):529-537 KALB VF; WOODS CW; TURI TG; DEY CR; SUTTER TR; LOPER JC PRIMARY STRUCTURE OF THE P450 LANOSTEROL DEMETHYLASE GENE FROM SACCHAROMYCES-CEREVISIAE	131	50
5389	17	10092 1996 CARCINOGENESIS 17(4):793-799 Kall MA; Vang O; Clausen J Effects of dietary broccoli on human in vivo drug metabolizing enzymes: Evaluation of caffeine, oestrone and chlorzoxazone metabolism	54	5
5390	3	6270 1988 KLINISCHE WOCHENSCHRIFT 66(6):229-235 KALOW W DEVELOPMENTS IN PHARMACOGENETICS - A SURVEY ON THE OCCASION OF HERKEN,HANS 75TH BIRTHDAY	3	0
5391	5	1461 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 147(2):734-& KALRA VK; MURTI CRK; BRODIE AF RESOLUTION AND RECONSTITUTION OF SUCCINOXIDASE PATHWAY OF MYCOBACTERIUM-PHLEI	17	0
5392	15	12782 2002 DRUG METABOLISM AND DISPOSITION 30(9):1022-1028 Kalsotra A; Anakk S; Boehme CL; Strobel HW Sexual dimorphism and tissue specificity in the expression of CYP4F forms in Sprague Dawley rats	3	0
5393	10	11832 1999 PLANT JOURNAL 19(2):183-193 Kaltenbach M; Schroder G; Schmelzer E; Lutz V; Schroder J Flavonoid hydroxylase from Catharanthus roseus: cDNA, heterologous expression, enzyme properties and cell-type specific expression in plants	13	2
5394	2	4914 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258(6):3855-3858 KALYANARAMAN B; MOTTLEY C; MASON RP A DIRECT ELECTRON-SPIN RESONANCE AND SPIN-TRAPPING INVESTIGATION OF PEROXYL FREE-RADICAL FORMATION BY HEMATIN HYDROPEROXIDE SYSTEMS	102	5
5395	10	4056 1980 BIOCHIMICA ET BIOPHYSICA ACTA 628(1):26-34 KAMAT JP; NARURKAR LM; MHATRE NA; NARURKAR MV NICOTINAMIDE-INDUCED HEPATIC-MICROSOMAL MIXED-FUNCTION OXIDASE SYSTEM IN RATS	18	2
5396	14	12766 2002 CYTOCHROME P450, PT C 357():301-310 Kamataki B; Fujita K Mutagenesis testing based on bacterial expression of human P450s	0	0
5397	10	5514 1985 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN 105(7):607-618 KAMATAKI T PURIFICATION AND REGULATION OF FORMS OF CYTOCHROME-P-450 PRESENT SPECIFICALLY IN LIVER-MICROSOMES OF MALE AND FEMALE RATS	2	0
5398	11	9909 1995 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN 115(5):370-377 KAMATAKI T MOLECULAR TOXICOLOGY OF CYTOCHROME-P450 - FOCUSING ON INTERSPECIES HOMOLOGY	4	3
5399	16	4122 1980 JAPANESE JOURNAL OF PHARMACOLOGY 30(6):841-851 KAMATAKI T; ANDO M; ISHII K; KATO R INHIBITION BY SKF 525-A OF 7-ETHOXYCOUMARIN O-DEETHYLATION IN MICROSOMAL AND THE RECONSTITUTED MONO-OXYGENASE SYSTEMS FROM PCB-TREATED RAT LIVERS	7	0
5400	19	4028 1980 BIOCHEMICAL PHARMACOLOGY 29(7):1015-1022 KAMATAKI T; ANDO M; YAMAZOE Y; ISHII K; KATO R SEX DIFFERENCE IN THE O-DEALKYLATION ACTIVITY OF 7- HYDROXYCOUMARIN O-ALKYL DERIVATIVES IN LIVER-MICROSOMES OF RATS	70	21

#	Cited nodes	Nodes / Authors	GCS	LCS
5401	15	12789 2002 DRUG METABOLISM REVIEWS 34(3):667-676 Kamataki T; Fujita K; Nakayama K; Yamazaki Y; Miyamoto M; Ariyoshi N Role of human cytochrome P450 (CYP) in the metabolic activation of nitrosamine derivatives: Application of genetically engineered Salmonella expressing human CYP	0	0
5402	2	1706 1971 YAKUGAKU ZASSHI 91(1):142-& KAMATAKI T; FUKAZAWA H; KITAGAWA H STUDIES ON HEXOBARBITAL DIFFERENCE SPECTRUM WITH MICROSOMES FROM 3-METHYLCHOLANTHRENE TREATED RATS	5	5
5403	26	4029 1980 BIOCHEMICAL PHARMACOLOGY 29(8):1141-1147 KAMATAKI T; KITADA M; CHIBA K; KITAGAWA H; IMAI Y; SATO R ENHANCEMENT BY CYANIDE OF ANILINE PARA-HYDROXYLATION ACTIVITY IN RAT-LIVER MICROSOMES	17	7
5404	6	1558 1971 CHEMICAL & PHARMACEUTICAL BULLETIN 19(8):1749-& KAMATAKI T; KITADA M; KITAGAWA H SUBSTRATE INDUCED DIFFERENCE SPECTRUM OF MICROSOMAL P-450 IN HUMAN LIVER	3	2
5405	6	2166 1973 CHEMICAL & PHARMACEUTICAL BULLETIN 21(1):8-11 KAMATAKI T; KITADA M; KITAGAWA H SOME OBSERVATIONS ON MICROSOMAL ELECTRON-TRANSPORT SYSTEM AND ACTIVITIES OF DRUG OXIDIZING ENZYMES IN HUMAN LIVER	6	0
5406	4	8329 1992 TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 168(2):89-95 KAMATAKI T; KITADA M; KOMORI M; YOKOI T; KITAMURA R HUMAN FETAL LIVER CYTOCHROME-P-450 - CAPACITY TO FORM GENOTOXIC METABOLITES	4	1
5407	14	3862 1979 JAPANESE JOURNAL OF PHARMACOLOGY 29(2):191-201 KAMATAKI T; KITADA M; SHIGEMATSU H; KITAGAWA H INVOLVEMENT OF CYTOCHROME P-448 AND P-450 IN NADH-DEPENDENT O- DEMETHYLATION OF P-NITROANISOLE IN RAT-LIVER MICROSOMES	29	7
5408	8	2476 1974 CHEMICAL & PHARMACEUTICAL BULLETIN 22(1):171-175 KAMATAKI T; KITAGAWA H DIPHASIC BINDING OF CARBON-MONOXIDE WITH CYTOCHROME-P-450 OF RAT-LIVER MICROSOMES REDUCED BY NADPH	2	1
5409	11	3261 1977 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 76(4):1007-1013 KAMATAKI T; KITAGAWA H INVOLVEMENT OF CYTOCHROME-P-450 IN NADH-DEPENDENT O- DEMETHYLATION OF PARA-NITROANISOLE IN PHENOBARBITAL-TREATED RABBIT LIVER-MICROSOMES	18	9
5410	5	3617 1978 JAPANESE JOURNAL OF PHARMACOLOGY 28(6):837-845 KAMATAKI T; KITAGAWA H; SUGITA O; NAMINOHIRA S EFFECTS OF VARIOUS COMPOUNDS ON LIPID PEROXIDATION MEDIATED BY DETERGENT-SOLUBILIZED RAT-LIVER NADPH-CYTOCHROME-C REDUCTASE	4	1
5411	14	4787 1983 BIOCHEMICAL PHARMACOLOGY 32(17):2479-2483 KAMATAKI T; MAEDA K; MATSUDA N; ISHII K; YAMAZOE Y; KATO R A HIGH-SPIN FORM OF CYTOCHROME-P-448 HIGHLY PURIFIED FROM PCB- TREATED RATS .2. CHARACTERISTIC REQUIREMENT OF CYTOCHROME-B5 FOR MAXIMUM ACTIVITY	13	2
5412	4	4972 1983 MOLECULAR PHARMACOLOGY 24(1):146-155 KAMATAKI T; MAEDA K; YAMAZOE Y; MATSUDA N; ISHII K; KATO R A HIGH-SPIN FORM OF CYTOCHROME-P-450 HIGHLY PURIFIED FROM POLYCHLORINATED BIPHENYL-TREATED RATS - CATALYTIC CHARACTERIZATION AND IMMUNOCHEMICAL QUANTITATION IN LIVER- MICROSOMES	168	49
5413	13	4763 1983 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 225(2):758-770 KAMATAKI T; MAEDA K; YAMAZOE Y; NAGAI T; KATO R SEX DIFFERENCE OF CYTOCHROME-P-450 IN THE RAT - PURIFICATION, CHARACTERIZATION, AND QUANTITATION OF CONSTITUTIVE FORMS OF CYTOCHROME-P-450 FROM LIVER-MICROSOMES OF MALE AND FEMALE RATS	279	96
5414	4	3616 1978 JAPANESE JOURNAL OF PHARMACOLOGY 28(6):819-827 KAMATAKI T; NAMINOHIRA S; SUGITA O; KITAGAWA H LIPID PEROXIDATION ACTIVITY MEDIATED BY NADPH-CYTOCHROME-C REDUCTASE PURIFIED FROM RABBIT LIVER-MICROSOMES	5	2
5415	7	2442 1974 BIOCHEMICAL PHARMACOLOGY 23(17):2485-2490 KAMATAKI T; OZAWA N; KITADA M; KITAGAWA H; SATO R OCCURRENCE OF AN INHIBITOR OF LIPID PEROXIDATION IN RAT-LIVER SOLUBLE FRACTION AND ITS EFFECT ON MICROSOMAL DRUG OXIDATIONS	51	10
5416	13	2167 1973 CHEMICAL & PHARMACEUTICAL BULLETIN 21(1):102-106 KAMATAKI T; SHIMOKAW.M; KITAGAWA H FURTHER STUDIES ON P-450 DIFFERENCE SPECTRA INDUCED BY VARIOUS COMPOUNDS IN LIVER-MICROSOMES FROM 3-METHYLCHOLANTHRENE TREATED RATS	8	6
5417	13	3780 1979 BIOCHEMICAL PHARMACOLOGY 28(13):1993-2000 KAMATAKI T; SUGIURA M; YAMAZOE Y; KATO R PURIFICATION AND PROPERTIES OF CYTOCHROME-P-450 AND NADPH- CYTOCHROME-C (P-450) REDUCTASE FROM HUMAN-LIVER MICROSOMES	41	7
5418	4	11091 1998 CANCER CHEMOTHERAPY AND PHARMACOLOGY 42():S50-S53 Kamataki T; Yokoi T; Fujita K; Ando Y Preclinical approach for identifying drug interactions	6	0
5419	1	4957 1983 LUNG 161(6):361-368 KAMBARA N; TAKAGI K; SATAKE T; SUGIYAMA S; OZAWA T MECHANISM RESPONSIBLE FOR ENDOTOXIN-INDUCED LUNG MICROSOMAL DYSFUNCTION IN RATS	15	1
5420	4	2755 1975 BULLETIN DE L ACADEMIE POLONAISE DES SCIENCES-SERIE DES SCIENCES BIOLOGIQUES 23(2):83-86 KAMINSKI Z; KANIUGA Z SOLUBILIZATION OF MICROSOMAL NADPH - CYTOCHROME-C REDUCTASE AND CYTOCHROME B5 FOLLOWING TRYPSIN AND PRONASE TREATMENT	0	0
5421	4	6565 1989 DRUG METABOLISM REVIEWS 20(2-4):479-487 KAMINSKY LS WARFARIN AS A PROBE OF CYTOCHROMES-P-450 FUNCTION	19	7
5422	24	8037 1992 CRITICAL REVIEWS IN TOXICOLOGY 21(6):407-422 KAMINSKY LS; FASCO MJ SMALL INTESTINAL CYTOCHROMES-P450	111	37
5423	17	3892 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(19):9657-9662 KAMINSKY LS; FASCO MJ; GUENGERICH FP COMPARISON OF DIFFERENT FORMS OF LIVER, KIDNEY, AND LUNG MICROSOMAL CYTOCHROME-P-450 BY IMMUNOLOGICAL INHIBITION OF REGIOSELECTIVE AND STEREOSELECTIVE METABOLISM OF WARFARIN	49	9
5424	21	5389 1985 EUROPEAN JOURNAL OF BIOCHEMISTRY 149(3):479-489 KAMINSKY LS; GUENGERICH FP CYTOCHROME-P-450 ISOZYME ISOZYME FUNCTIONAL INTERACTIONS AND NADPH-CYTOCHROME-P-450 REDUCTASE CONCENTRATIONS AS FACTORS IN MICROSOMAL METABOLISM OF WARFARIN	52	24
5425	10	10866 1997 PHARMACOLOGY & THERAPEUTICS 73(1):67-74 Kaminsky LS; Zhang ZY Human P450 metabolism of warfarin	87	13
5426	2	12826 2002 HEPATOLOGY 35(6):1351-1359 Kamiya A; Kojima N; Kinoshita T; Sakai Y; Miyaijma A Maturation of fetal hepatocytes in vitro by extracellular matrices and oncostatin M: Induction of tryptophan oxygenase	2	0
5427	3	8146 1992 JOURNAL OF BACTERIOLOGY 174(12):3921-3927 KAMLAGE B; BLAUT M CHARACTERIZATION OF CYTOCHROMES FROM METHANOSARCINA STRAIN GO1 AND THEIR INVOLVEMENT IN ELECTRON-TRANSPORT DURING GROWTH ON METHANOL	22	1
5428	2	8422 1993 ARCHIVES OF MICROBIOLOGY 159(2):189-196 KAMLAGE B; BOELTER A; BLAUT M SPECTROSCOPIC AND POTENTIOMETRIC CHARACTERIZATION OF CYTOCHROMES IN 2 SPOROMUSA SPECIES AND THEIR EXPRESSION DURING GROWTH ON SELECTED SUBSTRATES	11	0
5429	2	4129 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(2):595-601 KAMPA L; PEISACH J PURIFICATION AND CHARACTERIZATION OF HYDROXYINDOLE OXIDASE FROM THE GILLS OF MYTILUS-EDULIS	2	0
5430	4	435 1965 NAUNYN-SCHMIEDEBERGS ARCHIV FUR EXPERIMENTELLE PATHOLOGIE UND PHARMAKOLOGI 250(1):1-& KAMPFFME.H; KIESE M EFFECT OF CARBON MONOXIDE ON HYDROXYLATION OF ANILINE AND N- ETHYLANILINE BY MICROSOMAL ENZYMES	19	0
5431	6	2286 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(8):2868-2875 KAN KW; UNGAR F CHARACTERIZATION OF AN ADRENAL ACTIVATOR FOR CHOLESTEROL SIDE- CHAIN CLEAVAGE	55	7
5432	3	2579 1974 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 5(8):817-825 KAN KW; UNGAR F STIMULATION FACTORS FOR CHOLESTEROL SIDE-CHAIN CLEAVAGE IN CORPUS-LUTEUM AND ADRENAL-GLAND	15	2
5433	3	2756 1975 BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE 80(10):1193-1194 KANAEVA IP; ARCHAKOV AI HYDROXYLATION IN ISOLATED LIVER-CELLS	0	0
5434	10	7880 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 298(2):403-412 KANAEVA IP; NIKITYUK OV; DAVYDOV DR; DEDINSKII IR; KOEN YM; KUZNETSOVA GP; SKOTSELYAS ED; BACHMANOVA GI; ARCHAKOV AI COMPARATIVE-STUDY OF MONOMERIC RECONSTITUTED AND MEMBRANE MICROSOMAL MONOOXYGENASE SYSTEMS OF THE RABBIT LIVER .2. KINETIC-PARAMETERS OF REDUCTASE AND MONOOXYGENASE REACTIONS	11	6
5435	9	7171 1990 JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 38(11):1599-1605 KANAI K; WATANABE J; KANAMURA S MICROPHOTOMETRIC ANALYSIS OF CYTOCHROME-P-450 IN PERIPORTAL, MIDZONAL, AND PERIVENULAR HEPATOCYTES OF MICE TREATED WITH PHENOBARBITAL	12	4
5436	73	12103 2000 INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 198 198():109-152 Kanamura S; Watanabe J Cell biology of cytochrome P-450 in the liver	0	0
5437	3	1456 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 146(1):167-& KANAPKA JA; HAMILTON IR FLUORIDE INHIBITION OF ENOLASE ACTIVITY IN-VIVO AND ITS RELATIONSHIP TO INHIBITION OF GLUCOSE-6-P FORMATION IN STREPTOCOCCUS-SALIVARIUS	76	1
5438	3	1448 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 144(2):596-& KANAPKA JA; KHANDELW.RL; HAMILTON IR FLUORIDE INHIBITION OF GLUCOSE-6-P FORMATION IN STREPTOCOCCUS- SALIVARIUS - RELATION TO GLYCOGEN SYNTHESIS AND DEGRADATION	19	1
5439	2	4287 1981 BIOCHEMICAL PHARMACOLOGY 30(7):811-814 KANDASWAMI C; OBRIEN PJ PULMONARY METABOLISM OF BENZO(A) PYRENE - EFFECT OF ASBESTOS	5	0
5440	2	5657 1986 FIZIOLOGICHESKII ZHURNAL 32(5):579-584 KANDUL SV; YATSYK MI; KONONENKO VY A COMPARATIVE-STUDY OF THE CHLODITANE EFFECT ON THE CYTOCHROME- P-450 AND ADRENODOXIN CONTENT IN CERTAIN ORGANS OF DOGS AND RATS	1	0
5441	1	1319 1970 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 1(1):1-& KANE JF; PRIVITER.CA INHIBITOR EFFECTS ON ELECTRON TRANSPORT CHAIN OF TURTLE CARDIAC MITOCHONDRIA	3	0
5442	6	6543 1989 DEVELOPMENTAL PHARMACOLOGY AND THERAPEUTICS 12(2):96-105 KANE RE; LAMOTT J; FRANKLIN MR; GALINSKY RE PERINATAL CIMETIDINE EXPOSURE HAS NO APPARENT EFFECT ON HEPATIC DRUG OXIDATIVE OR CONJUGATIVE ACTIVITY IN ADULT MALE-RAT OFFSPRING	1	0
5443	5	4897 1983 JOURNAL OF BIOCHEMISTRY 94(4):1301-1306 KANG DC; NARABAYASHI H; SATA T; TAKESHIGE K KINETICS OF SUPEROXIDE FORMATION BY RESPIRATORY-CHAIN NADH- DEHYDROGENASE OF BOVINE HEART-MITOCHONDRIA	20	3
5444	13	9920 1996 AMERICAN JOURNAL OF CHINESE MEDICINE 24(1):19-29 Kang JJ; Chen YC; Kuo WC; Chen T; Cheng YW; Kuo ML; Ueng TH Modulation of microsomal cytochrome P450 by Scutellariae Radix and Gentianae scabrae Radix in rat liver	7	0
5445	17	336 1964 POSTEPY BIOCHEMII 10(1):7-& KANIUGA Z FLAVOPROTEINS OF RESPIRATORY CHAIN	7	1
5446	30	565 1966 POSTEPY BIOCHEMII 12(4):451-& KANIUGA Z; BRYLA J REVERSAL OF RESPIRATORY CHAIN	1	1
5447	7	800 1968 BIOCHIMICA ET BIOPHYSICA ACTA 153(1):60-& KANIUGA Z; GARDAS A; BRYLA J STUDIES ON MECHANISM OF INHIBITION OF MITOCHONDRIAL ELECTRON TRANSPORT BY ANTIMYCIN .I. REVERSAL OF INHIBITION BY DIETHYL ETHER EXTRACTION	10	4
5448	4	492 1966 BIOCHIMICA ET BIOPHYSICA ACTA 118(1):9-& KANIUGA Z; GARDAS A; JAKUBIAK M EFFECT OF DIGITONIN ON RESPIRATORY CHAIN ENZYMES OF A HEART- MUSCLE PREPARATION	10	3
5449	7	802 1968 BIOCHIMICA ET BIOPHYSICA ACTA 153(2):317-& KANIUGA Z; GARDAS A; JAKUBIAK M STUDIES ON RESPIRATORY CHAIN-LINKED REDUCED NICOTINAMIDE- ADENINE DINUCLEOTIDE DEHDYROGENASE .I. EFFECT OF DIETHYL ETHER ON PARTICULATE NADH DEHYDROGENASE	7	5
5450	4	823 1968 BULLETIN DE L ACADEMIE POLONAISE DES SCIENCES-SERIE DES SCIENCES BIOLOGIQUES 16(8):485-& KANIUGA Z; GARDAS A; JAKUBIAK M; BRYLA J STUDIES ON RESPIRATORY CHAIN-LINKED NADH DEHYDROGENASE .2. REACTIVATION OF NADH COENZYME-Q-1 REDUCTASE ACTIVITY IN DIETHYL ETHER AND PHOSPHOLIPASE-A TREATED HEART-MUSCLE PREPARATIONS	0	0
5451	12	6001 1987 XENOBIOTICA 17(7):793-805 KAO LR; WILKINSON CF INHIBITION OF CYTOCHROME-P-450C-MEDIATED BENZO[A]PYRENE HYDROXYLASE AND ETHOXYRESORUFIN O-DEETHYLASE BY DIHYDROSAFROLE	5	3
5452	6	2971 1976 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 70(4):1097-1101 KAPKE G; BARON J IMMUNOCHEMICAL EVIDENCE FOR INVOLVEMENT OF ADRENAL FERREDOXIN IN SIDE-CHAIN CLEAVAGE OF 20-ALPHA-HYDROXYCHOLESTEROL	4	4
5453	19	3640 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253(23):8604-8608 KAPKE GF; REDICK JA; BARON J IMMUNOHISTOCHEMICAL DEMONSTRATION OF AN ADRENAL FERREDOXIN-LIKE IRON-SULFUR PROTEIN IN RAT HEPATIC MITOCHONDRIA	10	3
5454	6	3525 1978 BIOCHEMICAL PHARMACOLOGY 27(11):1581-1589 KAPLAN E; GUTMANN HR; EMORY TH MICROSOMAL METABOLISM OF ARYLAMIDES BY RAT AND GUINEA-PIG .1. OXIDATION OF N-3-FLUORENYLACETAMIDE AT CARBON-ATOM-9 - MAJOR METABOLIC REACTION	9	3
5455	3	5756 1987 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 514():1-6 KAPPAS A MECHANISMS OF CHEMICAL-INDUCED PORPHYRINOPATHIES - INTRODUCTORY COMMENTS	1	0
5456	20	5711 1986 MICROBIOLOGICAL REVIEWS 50(3):244-258 KAPPELI O CYTOCHROMES-P-450 OF YEASTS	53	18
5457	8	5859 1987 CHEMISTRY AND PHYSICS OF LIPIDS 45(2-4):105-115 KAPPUS H A SURVEY OF CHEMICALS INDUCING LIPID-PEROXIDATION IN BIOLOGICAL-SYSTEMS	48	1
5458	2	1713 1972 ACTA ENDOCRINOLOGICA 71(2):374-& KAPPUS H; BOLT HM; REMMER H DEMETHYLATION OF MESTRANOL TO ETHINYLESTRADIOL IN-VITRO AND IN- VIVO	41	5
5459	6	2317 1973 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 4(2):121-128 KAPPUS H; BOLT HM; REMMER H AFFINITY OF ETHYNYL-ESTRADIOL AND MESTRANOL FOR UTERINE ESTROGEN RECEPTOR AND FOR MICROSOMAL MIXED-FUNCTION OXIDASE OF LIVER	24	2
5460	7	4555 1982 BIOCHEMISTRY-MOSCOW 47(6):739-748 KAPRELYANTS AS DYNAMIC PROTEIN ENSEMBLES IN BIOLOGICAL-MEMBRANES	1	0
5461	4	12199 2000 NEUROLOGY 55(5):644-649 Karadimas CL; Greenstein P; Sue CM; Joseph JT; Tanji K; Haller RG; Taivassalo T; Davidson MM; Shanske S; Bonilla E; DiMauro S Recurrent myoglobinuria due to a nonsense mutation in the COX I gene of mitochondrial DNA	25	3
5462	13	9232 1994 JOURNAL OF LIPID RESEARCH 35(7):1222-1231 KARAM WG; CHIANG JYL EXPRESSION AND PURIFICATION OF HUMAN CHOLESTEROL 7-ALPHA- HYDROXYLASE IN ESCHERICHIA-COLI	18	7
5463	12	6652 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264(33):19822-19827 KARARA A; DISHMAN E; BLAIR I; FALCK JR; CAPDEVILA JH ENDOGENOUS EPOXYEICOSATRIENOIC ACIDS - CYTOCHROME-P-450 CONTROLLED STEREOSELECTIVITY OF THE HEPATIC ARACHIDONIC-ACID EPOXYGENASE	78	41
5464	15	8690 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(18):13565-13570 KARARA A; MAKITA K; JACOBSON HR; FALCK JR; GUENGERICH FP; DUBOIS RN; CAPDEVILA JH MOLECULAR-CLONING, EXPRESSION, AND ENZYMATIC CHARACTERIZATION OF THE RAT-KIDNEY CYTOCHROME-P-450 ARACHIDONIC-ACID EPOXYGENASE	61	45
5465	6	3418 1977 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 203(2):409-416 KARASHIMA D; HIROKATA Y; SHIGEMATSU A; FURUKAWA T INVITRO METABOLISM OF HALOTHANE (2-BROMO-2-CHLORO-1,1,1- TRIFLUOROETHANE) BY HEPATIC MICROSOMAL CYTOCHROME-P-450	47	6
5466	2	10576 1997 BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM 1349(3):242-250 Karbowski M; Kurono C; Nishizawa Y; Horie Y; Soji T; Wakabayashi T Induction of megamitochondria by some chemicals inducing oxidative stress in primary cultured rat hepatocytes	20	0
5467	9	6435 1989 BIOCHEMICAL PHARMACOLOGY 38(9):1517-1525 KARENLAMPI SO; TUOMI K; KORKALAINEN M; RAUNIO H INDUCTION OF CYTOCHROME-P450IA1 IN MOUSE HEPATOMA-CELLS BY SEVERAL CHEMICALS - PHENOBARBITAL AND TCDD INDUCE THE SAME FORM OF CYTOCHROME-P450	30	1
5468	5	6583 1989 EUROPEAN JOURNAL OF BIOCHEMISTRY 181(1):143-148 KARENLAMPI SO; TUOMI K; KORKALAINEN M; RAUNIO H 2-(4'-CHLOROPHENYL)BENZOTHIAZOLE IS A POTENT INDUCER OF CYTOCHROME-P450IA1 IN A HUMAN AND A MOUSE-CELL LINE - ANOMALOUS CORRELATION BETWEEN PROTEIN AND MESSENGER-RNA INDUCTION	10	2
5469	14	10455 1996 YEAST 12(4):333-348 Kargel E; Menzel R; Honeck H; Vogel F; Bohmer A; Schunck WH Candida maltosa NADPH-cytochrome P450 reductase: Cloning of a full-length cDNA, heterologous expression in Saccharomyces cerevisiae and function of the N-terminal region for membrane anchoring and proliferation of the endoplasmic reticulum	22	7
5470	9	12715 2002 BIOCHEMISTRY 41(46):13514-13525 Kariakin A; Davydov D; Peterson JA; Jung C A new approach to the study of protein-protein interaction by FTIR: Complex formation between cytochrome P450BM-3 heme domain and FMN reductase domain	0	0
5471	14	5205 1984 LIFE SCIENCES 35(23):2327-2334 KARIYA K; LEE E; YAMAOKA M; ISHIKAWA H SELECTIVE INDUCTION OF CYTOCHROME-B5 AND NADH CYTOCHROME-B5 REDUCTASE BY PROPYLTHIOURACIL	8	4
5472	10	9904 1995 XENOBIOTICA 25(7):711-724 KARKI SB; DINNOCENZO JP ON THE MECHANISM OF AMINE OXIDATIONS BY P450	19	3
5473	8	9787 1995 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 117(13):3657-3657 KARKI SB; DINNOCENZO JP; JONES JP; KORZEKWA KR MECHANISM OF OXIDATIVE AMINE DEALKYLATION OF SUBSTITUTED N,N- DIMETHYLANILINES BY CYTOCHROME-P-450 - APPLICATION OF ISOTOPE EFFECT PROFILES	50	6
5474	3	6499 1989 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 67(8):912-921 KARMAZYN M SYNTHESIS AND RELEVANCE OF CARDIAC EICOSANOIDS WITH PARTICULAR EMPHASIS ON ISCHEMIA AND REPERFUSION	37	5
5475	21	5763 1987 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 256(1):179-193 KARP F; HARRIS JL; CROTEAU R METABOLISM OF MONOTERPENES - DEMONSTRATION OF THE HYDROXYLATION OF (+)-SABINENE TO (+)-CIS-SABINOL BY AN ENZYME PREPARATION FROM SAGE (SALVIA-OFFICINALIS) LEAVES	34	8
5476	8	6821 1990 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 276(1):219-226 KARP F; MIHALIAK CA; HARRIS JL; CROTEAU R MONOTERPENE BIOSYNTHESIS - SPECIFICITY OF THE HYDROXYLATIONS OF (-)-LIMONENE BY ENZYME PREPARATIONS FROM PEPPERMINT (MENTHA- PIPERITA), SPEARMINT (MENTHA-SPICATA), AND PERILLA (PERILLA- FRUTESCENS) LEAVES	63	10
5477	1	7779 1991 REVUE NEUROLOGIQUE 147(6-7):455-461 KARPATI G; ARNOLD D; MATTHEWS P; CARPENTER S; ANDERMANN F; SHOUBRIDGE E CORRELATIVE MULTIDISCIPLINARY APPROACH TO THE STUDY OF MITOCHONDRIAL ENCEPHALOMYOPATHIES	27	5
5478	10	5992 1987 VESTNIK AKADEMII MEDITSINSKIKH NAUK SSSR (7):60-67 KARUZINA II; ARCHAKOV AI ENZYME AUTOACTIVATION DURING CATALYSIS	3	0
5479	37	9144 1994 FREE RADICAL BIOLOGY AND MEDICINE 16(1):73-97 KARUZINA II; ARCHAKOV AI THE OXIDATIVE INACTIVATION OF CYTOCHROME-P450 IN MONOOXYGENASE REACTIONS	43	10
5480	12	9146 1994 FREE RADICAL BIOLOGY AND MEDICINE 17(6):557-567 KARUZINA II; ARCHAKOV AI HYDROGEN PEROXIDE-MEDIATED INACTIVATION OF MICROSOMAL CYTOCHROME-P450 DURING MONOOXYGENASE REACTIONS	24	6
5481	7	4302 1981 BIOCHEMISTRY-MOSCOW 46(10):1379-1385 KARUZINA II; BACHMANOVA GI; IZOTOV MV; OSIPOV AN; VARENITSA AI MECHANISM OF INHIBITORY EFFECT OF COPPER TYROSINE COMPLEX ON HYDROXYLASE REACTIONS	1	0
5482	6	3794 1979 BIOCHEMISTRY-MOSCOW 44(6):824-831 KARUZINA II; BACHMANOVA GI; MENGAZETDINOV DE; MYASOEDOVA KN; ZHIKHAREVA VO; KUZNETSOVA GP; ARCHAKOV AI ISOLATION AND PROPERTIES OF CYTOCHROME-P-450 FROM RABBIT LIVER- MICROSOMES	0	0
5483	8	4806 1983 BIOCHEMISTRY-MOSCOW 48(11):1536-1541 KARUZINA II; VARENITSA AI; ARCHAKOV AI COMPARATIVE INHIBITOR ANALYSIS OF THE HYDROXYLATION OF ANILINE BY CYTOCHROME-P-450 IN NADPH-DEPENDENT, CUMENE HYDROPEROXIDE- DEPENDENT, AND H2O2-DEPENDENT SYSTEMS	0	0
5484	19	6332 1988 VESTNIK AKADEMII MEDITSINSKIKH NAUK SSSR (1):53-62 KARYAKIN AV; DAVYDOV DR KINETICS OF ELECTRON-TRANSFER REACTION OF MONOOXYGENASE SYSTEM	0	0
5485	11	12504 2001 INSECT MOLECULAR BIOLOGY 10(3):191-196 Kasai S; Scott JG Cytochrome P450s CYP6D3 and CYP6D1 are part of a P450 gene cluster on autosome 1 in the house fly	2	0
5486	7	11244 1998 INSECT MOLECULAR BIOLOGY 7(2):185-190 Kasai S; Shono T; Yamakawa M Molecular cloning and nucleotide sequence of a cytochrome P450 cDNA from a pyrethroid-resistant mosquito, Culex quinquefasciatus Say	6	2
5487	1	11448 1999 AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 277(6):E976-E983 Kashiwagi A; Shinozaki K; Nishio Y; Maegawa H; Maeno Y; Kanazawa A; Kojima H; Haneda M; Hidaka H; Yasuda H; Kikkawa R Endothelium-specific activation of NAD(P)H oxidase in aortas of exogenously hyperinsulinemic rats	17	0
5488	14	4135 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(6):2606-2611 KASHIWAGI K; DAFELDECKER WP; SALHANICK HA PURIFICATION AND CHARACTERIZATION OF MITOCHONDRIAL CYTOCHROME- P-450 ASSOCIATED WITH CHOLESTEROL SIDE-CHAIN CLEAVAGE FROM BOVINE CORPUS-LUTEUM	32	9
5489	13	4640 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(5):2212-2217 KASHIWAGI K; MACDONALD AB; SALHANICK HA INHIBITION OF CHOLESTEROL SIDE-CHAIN CLEAVAGE BY ACTIVE-SITE DIRECTED ANTIBODY TO CORPUS-LUTEUM CYTOCHROME-P-450	13	4
5490	1	9203 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(41):25502-25514 KASHIWAYA Y; SATO K; TSUCHIYA N; THOMAS S; FELL DA; VEECH RL; PASSONNEAU JV CONTROL OF GLUCOSE-UTILIZATION IN WORKING PERFUSED RAT-HEART	113	0
5491	2	9389 1994 XENOBIOTICA 24(4):369-377 KASHIYAMA E; TODAKA T; ODOMI M; TANOKURA Y; JOHNSON DB; YOKOI T; KAMATAKI T; SHIMIZU T STEREOSELECTIVE PHARMACOKINETICS AND INTERCONVERSIONS OF FLOSEQUINAN ENANTIOMERS CONTAINING CHIRAL SULFOXIDE IN RAT	8	2
5492	13	10656 1997 DRUG METABOLISM AND DISPOSITION 25(6):716-724 Kashiyama E; Yokoi T; Odomi M; Funae Y; Inoue K; Kamataki T Cytochrome P450 responsible for the stereoselective S-oxidation of flosequinan in hepatic microsomes from rats and humans	4	2
5493	7	11883 1999 XENOBIOTICA 29(8):815-826 Kashiyama E; Yokoi T; Odomi M; Kamataki T Stereoselective S-oxidation and reduction of flosequinan in rat	0	0
5494	5	7648 1991 JOURNAL OF CHROMATOGRAPHY 587(1):43-54 KASTNER M; NEUBERT D HIGH-PERFORMANCE METAL CHELATE AFFINITY-CHROMATOGRAPHY OF CYTOCHROMES P-450 USING CHELATING SUPEROSE	9	2
5495	8	8190 1992 JOURNAL OF CHROMATOGRAPHY 625(1):55-66 KASTNER M; NEUBERT D PURIFICATION OF CYTOCHROMES-P-450 DERIVED FROM LIVER-MICROSOMES OF UNTREATED AND 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN-TREATED MARMOSET MONKEYS	4	2
5496	2	8356 1992 YEAST 8(9):691-697 KASUSKE A; WEDLER H; SCHULZE S; BECHER D EFFICIENT ELECTROPULSE TRANSFORMATION OF INTACT CANDIDA-MALTOSA CELLS BY DIFFERENT HOMOLOGOUS VECTOR PLASMIDS	11	0
5497	4	6214 1988 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 36(2):344-349 KATAGI T STRUCTURAL STUDIES OF THE VINYLTRIAZOLE FUNGICIDE DINICONAZOLE (ER PURE) RELATED TO ITS BINDING TO CYTOCHROME-P-450	5	0
5498	3	5747 1987 ACS SYMPOSIUM SERIES 355():340-352 KATAGI T; MIKAMI N; MATSUDA T; MIYAMOTO J APPLICATION OF MOLECULAR-ORBITAL CALCULATIONS TO ESTIMATE THE ACTIVE CONFORMATION OF AZOLE COMPOUNDS	1	0
5499	4	5926 1987 JOURNAL OF PESTICIDE SCIENCE 12(4):627-633 KATAGI T; MIKAMI N; MATSUDA T; MIYAMOTO J STRUCTURAL STUDIES OF THE PLANT-GROWTH REGULATOR UNICONAZOLE (ES PURE) AND COMPUTER-AIDED ANALYSIS OF ITS INTERACTION WITH CYTOCHROME-P-450	4	0
5500	5	894 1968 JOURNAL OF BIOLOGICAL CHEMISTRY 243(12):3543-& KATAGIRI M; GANGULI BN; GUNSALUS IC A SOLUBLE CYTOCHROME P-450 FUNCTIONAL IN METHYLENE HYDROXYLATION	255	126

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