#	Cited nodes	Nodes / Authors	GCS	LCS
4601	7	1775 1972 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 48(4):977-& HOFFSTRO.I; ORRENIUS S; ELLIN A; BACKSTRO.D; EHRENBERG A EVIDENCE FOR PRESENCE OF AN IRON SULFUR PROTEIN IN RAT-KIDNEY CORTEX MICROSOMES	12	0
4602	8	9807 1995 MOLECULAR & GENERAL GENETICS 248(1):95-102 HOHN TM; DESJARDINS AE; MCCORMICK SP THE TRI4 GENE OF FUSARIUM SPOROTRICHIOIDES ENCODES A CYTOCHROME-P450 MONOOXYGENASE INVOLVED IN TRICHOTHECENE BIOSYNTHESIS	35	5
4603	4	4993 1983 SCIENCE OF THE TOTAL ENVIRONMENT 32(1):13-27 HOHNBENTZ J; KURELEC B; ZAHN RK FAST EPHEMERAL DNA DAMAGE UPON BAP INJECTION	6	1
4604	3	7074 1990 FEBS LETTERS 273(1-2):219-222 HOHNE M; BECKERRABBENSTEIN V; KAHL GF; TANIGUCHI H REGULATION OF CYTOCHROME-P-450 CYPIA1 GENE-EXPRESSION AND PROTOONCOGENE EXPRESSION BY GROWTH-FACTORS IN PRIMARY HEPATOCYTES	23	4
4605	4	3160 1976 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 1(6):1067-1079 HOLBROOK DJ; WASHINGTON ME; LEAKE HB; BRUBAKER PE EFFECTS OF PLATINUM AND PALLADIUM SALTS ON PARAMETERS OF DRUG- METABOLISM IN RAT-LIVER	11	1
4606	6	3005 1976 BIOCHEMICAL PHARMACOLOGY 25(24):2747-2750 HOLDER GM; LITTLE PJ; RYAN AJ; WATSON TR INHIBITORS OF HEPATIC MIXED-FUNCTION OXIDASES .2. SOME BENZIMIDAZOLE, BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES	53	17
4607	25	11733 1999 JOURNAL OF CLINICAL INVESTIGATION 104(6):751-760 Holla VR; Makita K; Zaphiropoulos PG; Capdevila JH The kidney cytochrome P-4502C23 arachidonic acid epoxygenase is upregulated during dietary salt loading	21	6
4608	5	6155 1988 CHEMICAL REVIEWS 88(3):473-485 HOLLAND HL CHIRAL SULFOXIDATION BY BIOTRANSFORMATION OF ORGANIC SULFIDES	140	2
4609	6	11594 1999 CURRENT OPINION IN CHEMICAL BIOLOGY 3(1):22-27 Holland HL C-H activation	8	0
4610	9	11853 1999 STEROIDS 64(3):178-186 Holland HL Recent advances in applied and mechanistic aspects of the enzymatic hydroxylation of steroids by whole-cell biocatalysts	8	1
4611	1	6498 1989 CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE 67(2):268-274 HOLLAND HL; BROWN FM; CHENCHAIAH PC; CHERNISHENKO MJ; KHAN SH; RAO JA MICROBIAL HYDROXYLATION OF STEROIDS .12. HYDROXYLATION OF TESTOSTERONE AND RELATED STEROIDS BY GNOMONIA-FRUCTICOLA ATCC 11430	8	0
4612	4	8770 1993 MOLECULAR AND CELLULAR ENDOCRINOLOGY 94(2):R9-R13 HOLLAND OB; MATHIS JM; BIRD IM; RAINEY WE ANGIOTENSIN INCREASES ALDOSTERONE SYNTHASE MESSENGER-RNA LEVELS IN HUMAN NCI-H295 CELLS	23	3
4613	2	3468 1977 ZENTRALBLATT FUR BAKTERIOLOGIE MIKROBIOLOGIE UND HYGIENE SERIES A-MEDICAL MICROBIOLOGY INFECTIOUS DISEASES VIROLOGY PARASITOLOGY 237(2-3):351-357 HOLLANDER R INFLUENCE OF PERMEABILITY OF CELL-MEMBRANE ON TMPD OXIDASE ACTIVITY	4	0
4614	14	2285 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(7):2630-2633 HOLLENBE.PF; HAGER LP P-450 NATURE OF CARBON-MONOXIDE COMPLEX OF FERROUS CHLOROPEROXIDASE	94	0
4615	3	3731 1979 ACTA ENDOCRINOLOGICA 90(4):658-668 HOLLER M; DENGLER K; FABRICIUS R; BREUER H LIVER-CIRRHOSIS AND ESTROGEN METABOLISM - PERFUSION STUDIES WITH CIRRHOTIC RAT LIVERS	6	0
4616	20	9873 1995 PURE AND APPLIED CHEMISTRY 67(8-9):1487-1532 HOLLINGWORTH RM; KURIHARA N; MIYAMOTO J; OTTO S; PAULSON GD DETECTION AND SIGNIFICANCE OF ACTIVE METABOLITES OF AGROCHEMICALS AND RELATED XENOBIOTICS IN ANIMALS (TECHNICAL REPORT)	2	0
4617	7	13086 2003 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125(27):8209-8217 Hollmann F; Lin PC; Witholt B; Schmid A Stereospecific biocatalytic epoxidation: The first example of direct regeneration of a FAD-dependent monooxygenase for catalysis	0	0
4618	2	965 1969 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 130(1-2):653-& HOLLOSZY JO; OSCAI LB EFFECT OF EXERCISE ON ALPHA-GLYCEROPHOSPHATE DEHYDROGENASE ACTIVITY IN SKELETAL MUSCLE	68	3
4619	3	6681 1989 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 33(2):219-225 HOLLOWAY CD; KENYON CJ; DOWIE LJ; CORRIE JET; GRAY CE; FRASER R EFFECT OF THE BENZODIAZEPINES DIAZEPAM, DES-N-METHYLDIAZEPAM AND MIDAZOLAM ON CORTICOSTEROID BIOSYNTHESIS IN BOVINE ADRENOCORTICAL-CELLS INVITRO - LOCATION OF SITE OF ACTION	20	2
4620	10	5274 1985 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 237(2):477-489 HOLM KA; ENGELL RJ; KUPFER D REGIOSELECTIVITY OF HYDROXYLATION OF PROSTAGLANDINS BY LIVER- MICROSOMES SUPPORTED BY NADPH VERSUS H2O2 IN METHYLCHOLANTHRENE-TREATED AND CONTROL RATS - FORMATION OF NOVEL PROSTAGLANDIN METABOLITES	23	7
4621	24	8924 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 312(2):554-565 HOLMANS PL; SHET MS; MARTINWIXTROM CA; FISHER CW; ESTABROOK RW THE HIGH-LEVEL EXPRESSION IN ESCHERICHIA-COLI OF THE MEMBRANE- BOUND FORM OF HUMAN AND RAT CYTOCHROME B(5) AND STUDIES ON THEIR MECHANISM OF FUNCTION	42	42
4622	7	7531 1991 DRUG METABOLISM AND DISPOSITION 19(1):48-53 HOLSZTYNSKA EJ; WEBER WW; DOMINO EF GENETIC-POLYMORPHISM OF CYTOCHROME-P-450-DEPENDENT PHENCYCLIDINE HYDROXYLATION IN MICE - COMPARISON TO PHENCYCLIDINE HYDROXYLATION IN HUMANS	4	1
4623	2	84 1960 BIOCHEMICAL JOURNAL 76():179-189 HOLTON FA; COLPABOONSTRA J SPECTROPHOTOMETRIC OBSERVATIONS RELATING TO THE OXIDATION- REDUCTION POTENTIAL OF CYTOCHROME-B IN NON-PHOSPHORYLATING HEART-MUSCLE PARTICLES	32	18
4624	4	8791 1993 NATURE 366(6452):276-279 HOLTON TA; BRUGLIERA F; LESTER DR; TANAKA Y; HYLAND CD; MENTING JGT; LU CY; FARCY E; STEVENSON TW; CORNISH EC CLONING AND EXPRESSION OF CYTOCHROME-P450 GENES-CONTROLLING FLOWER COLOR	118	45
4625	2	9853 1995 PLANT CELL 7(7):1071-1083 HOLTON TA; CORNISH EC GENETICS AND BIOCHEMISTRY OF ANTHOCYANIN BIOSYNTHESIS	177	5
4626	5	10135 1996 CYTOCHROME P450, PT B 272():275-283 Holton TA; Lester DR Cloning of novel cytochrome P450 gene sequences via polymerase chain reaction amplification	10	3
4627	10	5034 1984 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 233(2):345-353 HOLTZCLAW WD; THURMAN RG; KAUFFMAN FC MITOCHONDRIAL MICROSOMAL INTERACTIONS INVITRO - USE OF MICROSOMAL 7-ETHYOXYCOUMARIN O-DEETHYLASE TO STUDY SUCCINATE- STIMULATED MALATE EFFLUX FROM MITOCHONDRIA	4	1
4628	2	703 1967 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 89(24):6341-& HOLTZMAN J; GILLETTE JR; MILNE GWA METABOLIC PRODUCTS OF NAPHTHALENE IN MAMMALIAN SYSTEMS	31	3
4629	9	1247 1970 BIOCHEMISTRY 9(4):995-& HOLTZMAN JL EFFECT OF 4,4-DIDEUTERATION OF REDUCED NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE ON MIXED FUNCTION OXIDASES OF HEPATIC MICROSOMES	27	19
4630	5	1373 1970 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 92(23):6993-& HOLTZMAN JL EFFECT OF 4,4-DIDEUTERATION OF NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE ON STEROID HYDROXYLATION	1	1
4631	63	3937 1979 PHARMACOLOGY & THERAPEUTICS 4(3):601-627 HOLTZMAN JL ROLE OF THE STIMULATION OF NADPH-CYTOCHROME-P-450 REDUCTASE- ACTIVITY IN HEPATIC, MICROSOMAL MIXED-FUNCTION OXIDASE ACTIVITY	8	0
4632	8	1377 1970 LIFE SCIENCE PART 1 PHYSIOLOGY & PHARMACOLOGY 9(18):1033-& HOLTZMAN JL; CARR ML INHIBITION OF HEPATIC MICROSOMAL MIXED FUNCTION OXIDASES BY D2O	13	12
4633	10	1741 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 150(1):227-& HOLTZMAN JL; CARR ML TEMPERATURE DEPENDENCE OF COMPONENTS OF HEPATIC MICROSOMAL MIXED-FUNCTION OXIDASES	48	21
4634	21	1978 1972 MOLECULAR PHARMACOLOGY 8(5):481-& HOLTZMAN JL; CARR ML INHIBITION BY DEUTERATED WATER OF MIXED-FUNCTION OXIDASES OF HEPATIC MICROSOMES OF MALE RAT	20	8
4635	13	4916 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258(9):5400-5404 HOLTZMAN JL; GANDER JE; ERICKSON RR THE EFFECT OF NADH AND LOW OXYGEN-PRESSURE ON THE HEPATIC- MICROSOMAL ETHYLMORPHINE N-DEMETHYLASE ACTIVITY OF THE MALE-RAT	12	0
4636	1	1007 1969 BIOCHEMICAL PHARMACOLOGY 18(8):1927-& HOLTZMAN JL; GILLETTE JR EFFECT OF DIETARY OROTIC ACID AND ADENINE SULFATE ON HEPATIC MICROSOMAL ENZYMES IN MALE AND FEMALE RATS	12	3
4637	6	787 1968 BIOCHEMICAL JOURNAL 110(3):407-& HOLTZMAN JL; GRAM TE; GIGON PL; GILLETTE JR DISTRIBUTION OF COMPONENTS OF MIXED-FUNCTION OXIDASE BETWEEN ROUGH AND SMOOTH ENDOPLASMIC RETICULUM OF LIVER CELLS	185	82
4638	8	6569 1989 DRUG METABOLISM REVIEWS 20(2-4):629-643 HOLTZMAN JL; PRASAD JS; ERICKSON RR; CHEN NQ; LIU YX; SRIVASTAVA SP DOES CYTOCHROME-P-450 MEDIATE THE EFFECTS OF NOREPINEPHRINE IN THE HEPATOCYTE	5	0
4639	4	1562 1971 CHEMICO-BIOLOGICAL INTERACTIONS 3(4):279-& HOLTZMAN JL; RUMACK BH KINETICS OF ETHYLMORPHINE ACTIVATION OF NADPH-CYTOCHROME P-450 REDUCTASE ACTIVITY OF HEPATIC MICROSOMES FROM MALE AND FEMALE RATS	9	8
4640	7	1661 1971 LIFE SCIENCE PART 1 PHYSIOLOGY & PHARMACOLOGY 10(12):669-& HOLTZMAN JL; RUMACK BH KINETICS OF CYTOCHROME P-450 REDUCTASE STIMULATION BY ETHYLMORPHINE	17	12
4641	12	2125 1973 BIOCHEMISTRY 12(12):2309-2313 HOLTZMAN JL; RUMACK BH KINETIC STUDIES ON CONTROL OF ETHYLMORPHINE N-DEMETHYLASE - ROLE OF ETHYLMORPHINE ACTIVATION OF REDUCED NICOTINAMIDE ADENINE-DINUCLEOTIDE PHOSPHATE-CYTOCHROME P-450 REDUCTASE	24	19
4642	9	2958 1976 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 173(2):710-719 HOLTZMAN JL; RUMACK BH; ERICKSON RR SPECTROPHOTOMETRIC AND RADIOMETRIC STUDIES ON INVIVO BINDING OF PHENOBARBITAL TO HEPATIC MICROSOMES	13	5
4643	1	8183 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267(30):21438-21445 HOLTZMAN MJ; TURK J; SHORNICK LP IDENTIFICATION OF A PHARMACOLOGICALLY DISTINCT PROSTAGLANDIN-H SYNTHASE IN CULTURED EPITHELIAL-CELLS	130	4
4644	7	10789 1997 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 15(9-10):1215-1222 Homma R; Kouyama T; Yamada M; Niimura Y; Krivosheev AV; Hara T; Kawato S Time-resolved study of effect of chlorpromazine on mobility of cytochrome P-450 and phospholipids in the inner membrane of adrenocortical mitochondria	2	0
4645	11	8430 1993 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 191(1):282-288 HOMMA T; ZHANG JY; SHIMIZU T; PRAKASH C; BLAIR IA; HARRIS RC CYCLOOXYGENASE-DERIVED METABOLITES OF 8,9-EPOXYEICOSATRIENOIC ACID ARE POTENT MITOGENS FOR CULTURED RAT GLOMERULAR MESANGIAL CELLS	6	3
4646	2	297 1964 BIOCHIMICA ET BIOPHYSICA ACTA 81(3):585-& HOMMES F; CHANCE B; ESTABROOK RW; RASMUSSE.UF IMIDAZOLE INHIBITION OF ENERGY-LINKED REDUCTION OF NAD+ BY SUCCINATE	4	4
4647	3	201 1963 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 11(1):1-& HOMMES F; ESTABROOK RW ROLE OF TRANSHYDROGENASE IN ENERGY-LINKED REDUCTION OF TPN	20	20
4648	3	156 1962 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 8(4):248-& HOMMES FA KINETICS OF SUCCINATE LINKED PYRIDINE NUCLEOTIDE REDUCTION IN SONIC PARTICLES FROM BEEF HEART MITOCHONDRIA	29	10
4649	3	213 1963 BIOCHIMICA ET BIOPHYSICA ACTA 71(3):595-& HOMMES FA A SOLUBLE FACTOR FROM MITOCHONDRIA STIMULATING RATE OF ENERGY- REQUIRING PYRIDINE NUCLEOTIDE REDUCTION	15	7
4650	5	217 1963 BIOCHIMICA ET BIOPHYSICA ACTA 77(2):173-& HOMMES FA SUCCINATE-LINKED NICOTINAMIDE-ADENINE DINUCLEOTIDE REDUCTION IN SUBMITOCHONDRIAL PARTICLES .1. KINETIC STUDIES OF REACTION	21	7
4651	5	218 1963 BIOCHIMICA ET BIOPHYSICA ACTA 77(2):183-& HOMMES FA SUCCINATE-LINKED NICOTINAMIDE-ADENINE DINUCLEOTIDE REDUCTION IN SUBMITOCHENDRIAL PARTICLES .2. STUDIES WITH INHIBITORS	13	8
4652	5	274 1964 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 108(1):36-& HOMMES FA OSCILLATORY REDUCTIONS OF PYRIDINE NUCLEOTIDES DURING ANAEROBIC GLYCOLYSIS IN BREWERS YEAST	61	28
4653	3	276 1964 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 108(3):500-& HOMMES FA OSCILLATION TIMES OF OSCILLATORY REDUCTION OF PYRIDINE NUCLEOTIDES DURING ANAEROBIC GLYCOLYSIS IN BREWERS YEAST	10	0
4654	2	404 1965 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY 14(2):231-& HOMMES FA OSCILLATORY REDUCTIONS OF PYRIDINE NUCLEOTIDES DURING ANAEROBIC GLYCOLYSIS IN YEASTS	10	6
4655	5	457 1966 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 113(2):324-& HOMMES FA MECHANISM OF CRABTREE EFFECT IN YEAST GROWN WITH DIFFERENT GLUCOSE CONCENTRATIONS	22	3
4656	1	977 1969 ARCHIVES OF DISEASE IN CHILDHOOD 44(238):688-& HOMMES FA; DEGROOT CJ; WILMINK CW; JONXIS JHP CARBAMYLPHOSPHATE SYNTHETASE DEFICIENCY IN AN INFANT WITH SEVERE CEREBRAL DAMAGE	45	0
4657	1	2222 1973 ENZYME 15(1-6):351-360 HOMMES FA; KRAAN GPB; BERGER R REGULATION OF ATP SYNTHESIS IN FETAL RAT-LIVER	17	0
4658	1	1526 1971 BIOCHIMICA ET BIOPHYSICA ACTA 230(2):327-& HOMMES FA; RICHTERS AR; BEERE A DEVELOPMENT OF ADENYLATE KINASE IN RAT LIVER	5	0
4659	1	300 1964 BIOCHIMICA ET BIOPHYSICA ACTA 86(2):427-& HOMMES FA; STEKHOVEN FMA APERIODIC CHANGES OF REDUCED NICOTINAMIDE-ADENINE DINUCLEOTIDE DURING ANAEROBIC GLYCOLYSIS IN BREWERS YEAST	27	21
4660	1	1871 1972 DEVELOPMENTAL BIOLOGY 29(2):250-& HOMMES FA; VANDERZW.P; LUITDEHA.G; OUDMANRI.AR DEVELOPMENT OF ENZYMES OF PHOSPHOCREATINE BIOSYNTHESIS IN RAT	5	0
4661	1	821 1968 BIOLOGIA NEONATORUM 13(3-4):181-& HOMMES FA; WILMINK CW DEVELOPMENTAL CHANGES OF GLYCOLYTIC ENZYMES IN RAT BRAIN LIVER AND SKELETAL MUSCLE	14	0
4662	2	1962 1972 JOURNAL OF PHYSIOLOGY-LONDON 220(3):601-& HOMSHER E; WALLNER A; MOMMAERT.WF; RICCHIUT.NV ACTIVATION HEAT, ACTIVATION METABOLISM AND TENSION-RELATED HEAT IN FROG SEMITENDINOSUS MUSCLES	147	0
4663	1	8782 1993 MOLECULAR PHARMACOLOGY 43(6):878-887 HONCHEL R; AKSOY IA; SZUMLANSKI C; WOOD TC; OTTERNESS DM; WIEBEN ED; WEINSHILBOUM RM HUMAN THIOPURINE METHYLTRANSFERASE - MOLECULAR-CLONING AND EXPRESSION OF T84 COLON-CARCINOMA CELL CDNA	51	6
4664	5	11019 1998 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 252(2):445-449 Honda S; Harada N; Ito S; Takagi Y; Maeda S Disruption of sexual behavior in male aromatase-deficient mice lacking exons 1 and 2 of the cyp19 gene	61	3
4665	3	12562 2001 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 79(1-5):255-260 Honda SI; Matsumoto T; Harada N Characterization and purification of a protein binding to the cis-acting element for brain-specific exon 1 of the mouse aromatase gene	0	0
4666	47	3675 1978 PHARMAZIE 33(6):317-321 HONECK H MIXED-FUNCTION MONO-OXYGENASE SYSTEMS OF ADRENAL-CORTEX	2	0
4667	10	12098 2000 HYPERTENSION 36(4):610-616 Honeck H; Gross V; Erdmann B; Kargel E; Neunaber R; Milia AF; Schneider W; Luft FC; Schunck WH Cytochrome P450-dependent renal arachidonic acid metabolism in desoxycorticosterone acetate-salt hypertensive mice	7	2
4668	2	10264 1996 JOURNAL OF CELLULAR PHYSIOLOGY 169(2):309-319 Hong JT; Glauert HP Comitogenicity of eicosanoids and the peroxisome proliferator ciprofibrate in cultured rat hepatocytes	14	2
4669	4	11407 1998 TOXICOLOGY 131(2-3):99-107 Hong JT; Glauert HP Stimulation of the DNA binding activity of AP-1 by the peroxisome proliferator ciprofibrate and eicosanoids in cultured rat hepatocytes	7	0
4670	4	10997 1998 ARCHIVES OF PHARMACAL RESEARCH 21(2):120-127 Hong JT; Yun YP Effects of the peroxisome proliferator ciprofibrate and prostaglandin F-2 alpha combination treatment on second messengers in cultured rat hepatocytes	0	0
4671	5	6509 1989 CANCER RESEARCH 49(11):2973-2979 HONG JY; PAN JM; NING SM; YANG CS MOLECULAR-BASIS FOR THE SEX-RELATED DIFFERENCE IN RENAL N- NITROSODIMETHYLAMINE DEMETHYLASE IN C3H-HEJ MICE	41	9
4672	11	10682 1997 ENVIRONMENTAL HEALTH PERSPECTIVES 105():759-762 Hong JY; Yang CS Genetic polymorphism of cytochrome P450 as a biomarker of susceptibility to environmental toxicity	25	3
4673	7	10525 1997 ARCHIVES OF TOXICOLOGY 71(4):266-269 Hong JY; Yang CS; Lee M; Wang YY; Huang WQ; Tan YZ; Patten CJ; Bondoc FY Role of cytochromes P450 in the metabolism of methyl tert-butyl ether in human livers	17	1
4674	5	10187 1996 EXPERIMENTAL AND MOLECULAR MEDICINE 28(4):167-172 Hong YS; Park HY; Park SS Diallyl sulfide down-regulates polycyclic aromatic hydrocarbon- induced cytochrome P450 1A1 in mouse liver and lung	0	0
4675	5	12928 2002 PLANT JOURNAL 32(4):495-508 Hong Z; Ueguchi-Tanaka M; Shimizu-Sato S; Inukai Y; Fujioka S; Shimada Y; Takatsuto S; Agetsuma M; Yoshida S; Watanabe Y; Uozu S; Kitano H; Ashikari M; Matsuoka M Loss-of-function of a rice brassinosteroid biosynthetic enzyme, C-6 oxidase, prevents the organized arrangement and polar elongation of cells in the leaves and stem	1	0
4676	2	11159 1998 DIABETES-METABOLISM REVIEWS 14(3):241-249 Honing MLH; Morrison PJ; Banga JD; Stroes ESG; Rabelink TJ Nitric oxide availability in diabetes mellitus	39	0
4677	5	813 1968 BIOCHIMICA ET BIOPHYSICA ACTA 162(4):624-& HONJO I; OZAWA K LYSOLECITHIN INHIBITION OF MITOCHONDRIAL METABOLISM	32	5
4678	5	878 1968 JOURNAL OF BIOCHEMISTRY 64(3):311-& HONJO I; OZAWA K; KITAMURA O; SAKAI A; OHSAWA T RAPID CHANGE OF PHOSPHOLIPID IN PANCREAS MITOCHONDRIA DURING AGING	5	1
4679	2	869 1968 JOURNAL OF BIOCHEMISTRY 63(3):332-& HONJO I; TAKASAN H; OZAWA K ON ISOLATION OF MITOCHONDRIA WITH HIGH RESPIRATORY CONTROL FROM GUINEA PIG PANCREAS	9	2
4680	3	875 1968 JOURNAL OF BIOCHEMISTRY 63(6):811-& HONJO I; TAKASAN H; OZAWA K; KITAMURA O; SAKAI A; OHSAWA T INHIBITORY EFFECT OF LYSOLECITHIN ON ELECTRON TRANSFER FROM NADH TO CYTOCHROME B	11	4
4681	6	7977 1992 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 33(3):313-317 HONKAKOSKI P; ARVELA P; JUVONEN R; LANG MA; KAIRALUOMA M; PELKONEN O HUMAN AND MOUSE-LIVER COUMARIN 7-HYDROXYLASES DO NOT METABOLIZE WARFARIN INVITRO	4	2
4682	15	7916 1992 BIOCHEMICAL PHARMACOLOGY 43(10):2121-2128 HONKAKOSKI P; AURIOLA S; LANG MA DISTINCT INDUCTION PROFILES OF 3 PHENOBARBITAL-RESPONSIVE MOUSE-LIVER CYTOCHROME-P450 ISOZYMES	28	11
4683	11	6044 1988 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 267(2):589-598 HONKAKOSKI P; AUTIO S; JUVONEN R; RAUNIO H; GELBOIN HV; PARK SS; PELKONEN O; LANG MA PYRAZOLE IS DIFFERENT FROM ACETONE AND ETHANOL AS AN INDUCER OF THE POLYSUBSTRATE MONOOXYGENASE SYSTEM IN MICE - EVIDENCE THAT PYRAZOLE-INDUCIBLE P450COH IS DISTINCT FROM ACETONE-INDUCIBLE P450AC	22	12
4684	7	7899 1992 BIOCHEMICAL JOURNAL 285():979-983 HONKAKOSKI P; KOJO A; LANG MA REGULATION OF THE MOUSE-LIVER CYTOCHROME-P450 2B SUBFAMILY BY SEX-HORMONES AND PHENOBARBITAL	52	26
4685	20	6388 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 273(1):42-57 HONKAKOSKI P; LANG MA MOUSE-LIVER PHENOBARBITAL-INDUCIBLE P450 SYSTEM - PURIFICATION, CHARACTERIZATION, AND DIFFERENTIAL INDUCIBILITY OF 4 CYTOCHROME-P450 ISOZYMES FROM THE D2 MOUSE	65	31
4686	17	7957 1992 BIOCHIMICA ET BIOPHYSICA ACTA 1122(1):6-14 HONKAKOSKI P; LINNALAKANKKUNEN A; USANOV SA; LANG MA HIGHLY HOMOLOGOUS CYTOCHROME-P-450 AND CYTOCHROME-B5 - A MODEL TO STUDY PROTEIN PROTEIN INTERACTIONS IN A RECONSTITUTED MONOOXYGENASE SYSTEM	13	7
4687	11	8817 1993 PHARMACOLOGY & TOXICOLOGY 72(2):107-112 HONKAKOSKI P; MAENPAA J; LEIKOLA J; PASANEN M; JUVONEN R; LANG MA; PELKONEN O; RAUNIO H CYTOCHROME P4502A-MEDIATED COUMARIN 7-HYDROXYLATION AND TESTOSTERONE HYDROXYLATION IN MOUSE AND RAT LUNG	22	10
4688	71	11947 2000 BIOCHEMICAL JOURNAL 347():321-337 Honkakoski P; Negishi M Regulation of cytochrome P450 (CYP) genes by nuclear receptors	68	14
4689	2	10470 1997 ANNALS OF CLINICAL BIOCHEMISTRY 34():45-54 Honour JW; Brook CGD Clinical indications for the use of urinary steroid profiles in neonates and children	9	0
4690	5	3162 1976 LIFE SCIENCES 18(3):279-290 HOOK GER; BEND JR PULMONARY METABOLISM OF XENOBIOTICS	93	14
4691	18	2174 1973 CHEMICO-BIOLOGICAL INTERACTIONS 7(4):205-222 HOOK GER; BEND JR; FOUTS JR EFFECT OF SOME BIPHENYL SOLUBILIZING AND SUSPENDING AGENTS ON BIPHENYL 4-HYDROXYLASE OF RABBIT LIVER-MICROSOMES	13	5
4692	6	2770 1975 CHEMICO-BIOLOGICAL INTERACTIONS 10(3):199-214 HOOK GER; HASEMAN JK; LUCIER GW INDUCTION AND SUPPRESSION OF HEPATIC AND EXTRAHEPATIC MICROSOMAL FOREIGN-COMPOUND-METABOLIZING ENZYME-SYSTEMS BY 2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN	144	21
4693	2	9581 1995 CHEST 107(2):317-322 HOOPER RG; THOMAS AR; KEARL RA MITOCHONDRIAL ENZYME DEFICIENCY CAUSING EXERCISE LIMITATION IN NORMAL-APPEARING ADULTS	10	6
4694	3	7000 1990 CLINICAL PHARMACOLOGY & THERAPEUTICS 48(6):633-640 HOOPER WD; QING MS THE INFLUENCE OF AGE AND GENDER ON THE STEREOSELECTIVE METABOLISM AND PHARMACOKINETICS OF MEPHOBARBITAL IN HUMANS	56	4
4695	3	8089 1992 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 17(1):51-59 HOOPER WD; WATT JA; MCKINNON GE; REILLY PEB METABOLISM OF DIAZEPAM AND RELATED BENZODIAZEPINES BY HUMAN LIVER-MICROSOMES	11	2
4696	9	7924 1992 BIOCHEMICAL PHARMACOLOGY 44(4):787-796 HOPKINS NE; FOROOZESH MK; ALWORTH WL SUICIDE INHIBITORS OF CYTOCHROME-P450-1A1 AND CYTOCHROME-P450- 2B1	46	16
4697	8	5371 1985 DRUG METABOLISM AND DISPOSITION 13(3):364-367 HORAI Y; WHITE PF; TREVOR AJ THE EFFECT OF ETOMIDATE ON RABBIT LIVER MICROSOMAL DRUG- METABOLISM INVITRO	10	4
4698	1	9317 1994 OXYGEN RADICALS IN BIOLOGICAL SYSTEMS, PT D 234():572-580 HORAKOVA L; SIES H; STEENKEN S ANTIOXIDANT ACTION OF STOBADINE	27	0
4699	5	8350 1992 XENOBIOTICA 22(5):515-522 HORBACH GJMJ; VANASTEN JG; RIETJENS IMCM; KREMERS P; VANBEZOOIJEN CFA THE EFFECT OF AGE ON INDUCIBILITY OF VARIOUS TYPES OF RAT-LIVER CYTOCHROME-P-450	15	2
4700	1	6886 1990 BIOCHEMICAL PHARMACOLOGY 40(3):529-533 HORBACH GJMJ; VANASTEN JG; VANBEZOOIJEN CFA THE INFLUENCE OF AGING ON THE INDUCTION OF THE MESSENGER-RNAS OF RAT-LIVER CYTOCHROME-P450IIB1 AND CYTOCHROME-P450IIB2	17	5

#	Cited nodes	Nodes / Authors	GCS	LCS
4701	5	620 1967 BIOCHEMICAL JOURNAL 104(3):C50-& HORGAN DJ; SINGER TP CHARACTERISTICS OF BINDING OF ROTENONE IN RESPIRATORY CHAIN AND INHIBITION SITES OF AMYTAL AND PIERICIDIN A	11	2
4702	8	882 1968 JOURNAL OF BIOLOGICAL CHEMISTRY 243(4):834-& HORGAN DJ; SINGER TP; CASIDA JE STUDIES ON RESPIRATORY CHAIN-LINKED REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE	160	22
4703	6	3693 1978 SEIKAGAKU 50(5):352-357 HORIE S SPECTRAL CHARACTERISTICS AND COORDINATION STRUCTURE OF HEMOPROTEIN P-450	0	0
4704	4	529 1966 JOURNAL OF BIOCHEMISTRY 60(6):660-& HORIE S; KINOSHIT.T; SHIMAZON.N STUDIES ON P-450 .2. ON ABSORPTION SPECTRUM OF P-450 IN MITOCHONDRIAL FRAGMENTS FROM BOVINE ADRENAL CORTEX	14	11
4705	11	2870 1975 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 6(3-4):401-409 HORIE S; WATANABE T PROPERTIES OF HIGH-SPIN TYPE-P-450 PREPARATIONS FROM BOVINE ADRENAL-CORTEX MITOCHONDRIA	15	6
4706	5	7106 1990 JOURNAL OF BACTERIOLOGY 172(7):3644-3653 HORII M; ISHIZAKI T; PAIK SY; MANOME T; MUROOKA Y AN OPERON CONTAINING THE GENES FOR CHOLESTEROL OXIDASE AND A CYTOCHROME-P-450-LIKE PROTEIN FROM A STREPTOMYCES SP	57	11
4707	1	165 1962 BIOCHEMISTRY 1(6):1141-& HORIO T; KAMEN MD OBSERVATIONS ON RESPIRATORY SYSTEM OF RHODOSPIRILLUM RUBRUM	53	1
4708	4	3615 1978 JAPANESE JOURNAL OF EXPERIMENTAL MEDICINE 48(1):27-33 HORIUCHI T; OHTSUBO K; SAITO M DEVELOPMENT OF RESISTANCE TO HEPATOTOXIC EFFECT OF FURYLFURAMIDE BY PRETREATMENT WITH ITS SUB-NECROTIC DOSES AND CARBON-TETRACHLORIDE	0	0
4709	5	7002 1990 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 95(3):613-618 HORNING M; COLLATZ KG 1ST DESCRIPTION OF THE GLYCOLYTIC OSCILLATOR OF AN INSECT, THE BLOWFLY PHORMIA-TERRAENOVAE	4	1
4710	9	4139 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(9):4020-4027 HORNSBY PJ REGULATION OF CYTOCHROME P-450-SUPPORTED 11 BETA-HYDROXYLATION OF DEOXYCORTISOL BY STEROIDS, OXYGEN, AND ANTIOXIDANTS IN ADRENOCORTICAL CELL-CULTURES	129	26
4711	15	5640 1986 ENDOCRINE RESEARCH 12(4):469-494 HORNSBY PJ CYTOCHROME-P-450 PSEUDOSUBSTRATE INTERACTIONS AND THE ROLE OF ANTIOXIDANTS IN THE ADRENAL-CORTEX	18	3
4712	8	5932 1987 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 27(4-6):1161-1171 HORNSBY PJ PHYSIOLOGICAL AND PATHOLOGICAL EFFECTS OF STEROIDS ON THE FUNCTION OF THE ADRENAL-CORTEX	15	0
4713	2	9595 1995 DEHYDROEPIANDROSTERONE (DHEA) AND AGING 774():29-46 Hornsby PJ Biosynthesis of DHEAS by the human adrenal cortex and its age- related decline	38	1
4714	11	4962 1983 MOLECULAR AND CELLULAR ENDOCRINOLOGY 30(1):1-20 HORNSBY PJ; CRIVELLO JF THE ROLE OF LIPID-PEROXIDATION AND BIOLOGICAL ANTI-OXIDANT IN THE FUNCTION OF THE ADRENAL-CORTEX .1. A BACKGROUND REVIEW	94	15
4715	13	4963 1983 MOLECULAR AND CELLULAR ENDOCRINOLOGY 30(2):123-147 HORNSBY PJ; CRIVELLO JF THE ROLE OF LIPID-PEROXIDATION AND BIOLOGICAL ANTI-OXIDANT IN THE FUNCTION OF THE ADRENAL-CORTEX .2.	135	7
4716	2	3587 1978 ENDOCRINOLOGY 102(3):926-936 HORNSBY PJ; GILL GN CHARACTERIZATION OF ADULT BOVINE ADRENOCORTICAL-CELLS THROUGHOUT THEIR LIFE-SPAN IN TISSUE-CULTURE	75	9
4717	8	8042 1992 DNA AND CELL BIOLOGY 11(5):385-395 HORNSBY PJ; YANG LQ; RAJU SG; MAGHSOUDLOU SS; LALA DS; NALLASETH FS DEMETHYLATION OF SPECIFIC SITES IN THE 5'-FLANKING REGION OF THE CYP17-GENES WHEN BOVINE ADRENOCORTICAL-CELLS ARE PLACED IN CULTURE	10	5
4718	6	10218 1996 IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 18(2):237-245 Hornstein EH; Vassilopoulos D; Thomas DE; Friedman FK; Tsokos GC Modulation of human T-lymphocyte plasma membrane Ca+2 permeability by imidazole antimycotics.	3	0
4719	23	9974 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 332(2):261-268 Hornsten L; Bylund J; Oliw EH Dexamethasone induces bisallylic hydroxylation of polyunsaturated fatty acids by rat liver microsomes	9	3
4720	26	10457 1997 ACTA GASTRO-ENTEROLOGICA BELGICA 60(1):2-10 Horsmans Y Major cytochrome P-450 families: Implications in health and liver diseases	4	0
4721	5	11645 1999 EUROPEAN HEART JOURNAL SUPPLEMENTS 1(T):T7-T12 Horsmans Y Differential metabolism of statins: importance in drug-drug interactions	5	0
4722	3	9847 1995 PHARMACOLOGY & TOXICOLOGY 77(4):247-249 HORSMANS Y; DEKONINCK X; GEUBEL AP; PAUWELS S MICROSOMAL FUNCTION IN HEPATITIS-B SURFACE-ANTIGEN HEALTHY CARRIERS - ASSESSMENT OF CYTOCHROME-P450 1A2 ACTIVITY BY THE C- 14 CAFFEINE BREATH TEST	10	1
4723	15	8301 1992 PHARMACOLOGY & TOXICOLOGY 71(4):258-261 HORSMANS Y; DESAGER JP; HARVENGT C ABSENCE OF CYP3A GENETIC-POLYMORPHISM ASSESSED BY URINARY- EXCRETION OF 6-BETA-HYDROXYCORTISOL IN 102 HEALTHY-SUBJECTS ON RIFAMPICIN	26	12
4724	5	8806 1993 PHARMACOLOGICAL RESEARCH 28(3):243-248 HORSMANS Y; DESAGER JP; VANDENBERGE V; ABRASSART M; HARVENGT C EFFECTS OF SIMVASTATIN AND PRAVASTATIN ON 6-BETA- HYDROXYCORTISOL EXCRETION, A POTENTIAL MARKER OF CYTOCHROME-P- 450-3A	18	3
4725	10	7812 1991 XENOBIOTICA 21(12):1559-1570 HORSMANS Y; LANNES D; LARREY D; TINEL M; LETTERON P; LOEPER J; PESSAYRE D NILUTAMIDE INHIBITS MEPHENYTOIN 4-HYDROXYLATION IN UNTREATED MALE-RATS AND IN HUMAN LIVER-MICROSOMES	4	1
4726	32	5867 1987 CRC CRITICAL REVIEWS IN TOXICOLOGY 18(1):27-79 HORTON AA; FAIRHURST S LIPID-PEROXIDATION AND MECHANISMS OF TOXICITY	188	3
4727	1	2310 1973 JOURNAL OF NEUROCHEMISTRY 21(3):507-520 HORTON RW; MELDRUM BS; BACHELAR.HS ENZYMIC AND CEREBRAL METABOLIC EFFECTS OF 2-DEOXY-D-GLUCOSE	126	0
4728	3	8529 1993 BIOTECHNOLOGY PROGRESS 9(6):666-670 HORVATH JJ; GLAZIER SA; SPANGLER CJ IN-SITU FLUORESCENCE CELL MASS MEASUREMENTS OF SACCHAROMYCES- CEREVISIAE USING CELLULAR TRYPTOPHAN	10	0
4729	12	11618 1999 DRUG METABOLISM AND DISPOSITION 27(12):1512-1518 Hosagrahara VP; Hansen LK; Remmel RP Induction of the metabolism of midazolam by rifampin in cultured porcine hepatocytes: Preliminary evidence for CYP3A isoforms in pigs	5	1
4730	14	10976 1998 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 353(2):365-373 Hosea NA; Guengerich FP Oxidation of nonionic detergents by cytochrome P450 enzymes	12	5
4731	26	11957 2000 BIOCHEMISTRY 39(20):5929-5939 Hosea NA; Miller GP; Guengerich FP Elucidation of distinct ligand binding sites for cytochrome P450 3A4	53	17
4732	1	1531 1971 BIOCHIMICA ET BIOPHYSICA ACTA 237(2):227-& HOSKINS DD ENZYMIC CONTROL OF FRUCTOLYSIS IN PRIMATE SPERMATOZOA	27	3
4733	21	11478 1999 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 366(2):199-206 Hosny G; Roman LJ; Mostafa MH; Masters BSS Unique properties of purified, Escherichia coli-expressed constitutive cytochrome P4504A5	7	3
4734	19	2901 1975 SEIKAGAKU 47(4):151-175 HOSOYA T THYROID PEROXIDASE - ITS PROPERTIES AND PHYSIOLOGICAL-ROLE	2	0
4735	5	2219 1973 ENDOCRINOLOGIA JAPONICA 20(6):555-564 HOSOYA T; MATSUKAW.S; NAGAI Y FURTHER STUDIES ON LOCALIZATION OF PEROXIDASE IN PIG THYROID- CELLS	9	3
4736	5	629 1967 BIOCHEMISTRY 6(4):1021-& HOSOYA T; MORRISON M A STUDY OF HEMOPROTEINS OF THYROID MICROSOMES WITH EMPHASIS ON THYROID PEROXIDASE	63	18
4737	7	6707 1989 MOLECULAR PHARMACOLOGY 35(3):279-285 HOSTETLER KA; WRIGHTON SA; MOLOWA DT; THOMAS PE; LEVIN W; GUZELIAN PS COINDUCTION OF MULTIPLE HEPATIC CYTOCHROME-P-450 PROTEINS AND THEIR MESSENGER-RNAS IN RATS TREATED WITH IMIDAZOLE ANTIMYCOTIC AGENTS	77	34
4738	18	9672 1995 FEBS LETTERS 374(3):345-350 HOTZE M; SCHRODER G; SCHRODER J CINNAMATE 4-HYDROXYLASE FROM CATHARANTHUS-ROSEUS, AND A STRATEGY FOR THE FUNCTIONAL EXPRESSION OF PLANT CYTOCHROME-P- 450 PROTEINS AS TRANSLATIONAL FUSIONS WITH P-450 REDUCTASE IN ESCHERICHIA-COLI	26	10
4739	6	2797 1975 EUROPEAN JOURNAL OF BIOCHEMISTRY 54(1):11-18 HOUSTEK J; CANNON B; LINDBERG O GLYCEROL-3-PHOSPHATE SHUTTLE AND ITS FUNCTION IN INTERMEDIARY METABOLISM OF HAMSTER BROWN-ADIPOSE TISSUE	42	14
4740	3	3420 1977 JOURNAL OF PHARMACY AND PHARMACOLOGY 29():P76-P76 HOUSTON JB; ALGAILANY KAS; BRIDGES JW EFFECT OF STRUCTURAL MODIFICATIONS ON DRUG-HEPATIC MICROSOMAL INTERACTIONS	0	0
4741	22	12039 2000 DRUG METABOLISM AND DISPOSITION 28(3):246-254 Houston JB; Kenworthy KE In vitro-in vivo scaling of CYP kinetic data not consistent with the classical Michaelis-Menten model	57	11
4742	2	11715 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(8):4985-4994 Houston M; Estevez A; Chumley P; Aslan M; Marklund S; Parks DA; Freeman BA Binding of xanthine oxidase to vascular endothelium - Kinetic characterization and oxidative impairment of nitric oxide- dependent signaling	43	0
4743	5	9172 1994 JOURNAL OF BIOCHEMICAL TOXICOLOGY 9(2):71-78 HOWARD PC; MCMANUS ME; KOOP DR THE ROLE OF CYTOCHROME-P450 2C3 IN RABBIT LIVER MICROSOMAL METABOLISM OF 1-NITROPYRENE AND 3-NITROFLUORANTHENE	5	0
4744	3	6146 1988 CANCER RESEARCH 48(15):4261-4265 HOWARD PC; REED KA; KOOP DR OXIDATIVE-METABOLISM OF 1-NITROPYRENE BY RABBIT LIVER- MICROSOMES AND PURIFIED MICROSOMAL CYTOCHROME-P-450 ISOZYMES	21	4
4745	1	204 1963 BIOCHEMICAL JOURNAL 89(1):P18-& HOWLAND JL PHOSPHORYLATION COUPLED TO OXIDATION OF TETRAMETHYL-P- PHENYLENEDIAMINE IN RAT-LIVER MITOCHONDRIA	0	0
4746	3	215 1963 BIOCHIMICA ET BIOPHYSICA ACTA 73(4):665-& HOWLAND JL REVERSIBILITY OF INHIBITION BY 2-HEPTYL-4-HYDROXYQUINOLINE-N- OXIDE AND 2-HYDROXY-3(3-METHYLBUTYL)-1,4-NAPHTHOQUINONE OF SUCCINATE OXIDATION	31	6
4747	2	220 1963 BIOCHIMICA ET BIOPHYSICA ACTA 77(3):419-& HOWLAND JL PHOSPHORYLATION COUPLED TO OXIDATION OF TETRAMETHYL-RHO- PHENYLENEDIAMINE IN RAT-LIVER MITOCHONDRIA	48	14
4748	4	392 1965 BIOCHIMICA ET BIOPHYSICA ACTA 105(2):205-& HOWLAND JL INHIBITION OF MITOCHONDRIAL SUCCINATE OXIDATION BY ALKYL HYDROXY NAPHTHOQUINONES	22	5
4749	4	801 1968 BIOCHIMICA ET BIOPHYSICA ACTA 153(1):309-& HOWLAND JL REVERSIBILITY OF ANTIMYCIN INHBITION	9	3
4750	4	980 1969 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 35(3):331-& HOWLAND JL; BOTTOMY DP ION FLUX COUPLED TO MITOCHONDRIAL OXIDATION OF TETRAMETHYL-RHO- PHENYLENEDIAMINE	0	0
4751	7	1502 1971 BIOCHEMICAL PHARMACOLOGY 20(7):1463-& HOWLAND RD; BURKHALT.A SOME EFFECTS OF 3-METHYLCHOLANTHRENE ON URIDINE DIPHOSPHATE GLUCURONYLTRANSFERASE IN RAT AND GUINEA PIG	21	3
4752	1	1083 1969 GERONTOLOGIA 15(1):52-& HRACHOVE.JP AGE CHANGES IN AMINO ACID INCORPORATION BY RAT LIVER MICROSOMES	44	0
4753	3	3773 1979 BIOCHEMICAL PHARMACOLOGY 28(7):1157-1161 HRADEC J; DUSEK Z; BAHNA L CARCINOGENIC HYDROCARBONS INCREASE THE ACCEPTANCE OF TRANSFER RIBONUCLEIC-ACID FOR METHIONINE	8	0
4754	14	2419 1974 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 60(2):771-778 HRYCAY EG; ESTABROOK RW EFFECT OF EXTRA BOUND CYTOCHROME-B5 ON CYTOCHROME P-450- DEPENDENT ENZYME-ACTIVITIES IN LIVER-MICROSOMES	26	26
4755	10	2689 1975 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 66(1):209-216 HRYCAY EG; GUSTAFSSON JA; INGELMANSUNDBERG M; ERNSTER L SODIUM PERIODATE, SODIUM-CHLORITE, ORGANIC HYDROPEROXIDES, AND H2O2 AS HYDROXYLATING AGENTS IN STEROID HYDROXYLATION REACTIONS CATALYZED BY PARTIALLY PURIFIED CYTOCHROME-P-450	120	37
4756	8	2814 1975 FEBS LETTERS 56(1):161-165 HRYCAY EG; GUSTAFSSON JA; INGELMANSUNDBERG M; ERNSTER L SODIUM PERIODATE, SODIUM-CHLORITE, AND ORGANIC HYDROPEROXIDES AS HYDROXYLATING AGENTS IN HEPATIC MICROSOMAL STEROID HYDROXYLATION REACTIONS CATALYZED BY CYTOCHROME-P-450	34	13
4757	19	3080 1976 EUROPEAN JOURNAL OF BIOCHEMISTRY 61(1):43-52 HRYCAY EG; GUSTAFSSON JA; INGELMANSUNDBERG M; ERNSTER L INVOLVEMENT OF CYTOCHROME-P-450 IN HEPATIC MICROSOMAL STEROID HYDROXYLATION REACTIONS SUPPORTED BY SODIUM PERIODATE, SODIUM- CHLORITE, AND ORGANIC HYDROPEROXIDES	105	42
4758	23	2667 1975 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 166(1):145-151 HRYCAY EG; JONEN HG; LU AYH; LEVIN W RECONSTITUTION OF REDUCED NICOTINAMIDE ADENINE-DINUCLEOTIDE PHOSPHATE AND REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE- PEROXIDASE ACTIVITIES FROM SOLUBILIZED COMPONENTS OF RAT-LIVER MICROSOMES	40	18
4759	14	1457 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 147(1):14-& HRYCAY EG; OBRIEN PJ CYTOCHROME P-450 AS A MICROSOMAL PEROXIDASE UTILIZING A LIPID PEROXIDE SUBSTRATE	196	66
4760	20	1757 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 153(2):480-494 HRYCAY EG; OBRIEN PJ CYTOCHROME-P-450 AS A MICROSOMAL PEROXIDASE IN STEROID HYDROPEROXIDE REDUCTION	101	44
4761	25	2064 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 157(1):7-22 HRYCAY EG; OBRIEN PJ MICROSOMAL ELECTRON-TRANSPORT .1. REDUCED NICOTINAMIDE ADENINE- DINUCLEOTIDE PHOSPHATE-CYTOCHROME-C REDUCTASE AND CYTOCHROME-P- 450 AS ELECTRON CARRIERS IN MICROSOMAL NADPH-PEROXIDASE ACTIVITY	68	27
4762	20	2392 1974 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 160(1):230-245 HRYCAY EG; OBRIEN PJ MICROSOMAL ELECTRON-TRANSPORT .2. REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE-CYTOCHROME-B5 REDUCTASE AND CYTOCHROME-P-450 AS ELECTRON CARRIERS IN MICROSOMAL NADH-PEROXIDASE ACTIVITY	93	37
4763	18	2405 1974 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 165(1):331-339 HRYCAY EG; PROUGH RA REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE-CYTOCHROME-B5 REDUCTASE AND CYTOCHROME-B5 AS ELECTRON CARRIERS IN NADH- SUPPORTED CYTOCHROME P-450-DEPENDENT ENZYME-ACTIVITIES IN LIVER-MICROSOMES	53	34
4764	11	12440 2001 DRUG METABOLISM AND DISPOSITION 29(3):268-273 Hsieh KP; Lin YY; Cheng CL; Lai ML; Lin MS; Siest JP; Huang JD Novel mutations of CYP3A4 in Chinese	12	5
4765	1	8244 1992 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 3(4):947-952 HSU CH; PATEL S UREMIC PLASMA CONTAINS FACTORS INHIBITING 1-ALPHA-HYDROXYLASE ACTIVITY	14	0
4766	19	10234 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(6):3306-3310 Hsu LC; Hsu NC; Guzova JA; Guzov VM; Chang SF; Chung BC The common I172N mutation causes conformational change of cytochrome P450c21 revealed by systematic mutation, kinetic, and structural studies	13	5
4767	6	9819 1995 MOLECULAR PHARMACOLOGY 48(3):559-567 HSU MH; PALMER CNA; GRIFFIN KJ; JOHNSON EF A SINGLE AMINO-ACID CHANGE IN THE MOUSE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-ALPHA ALTERS TRANSCRIPTIONAL RESPONSES TO PEROXISOME PROLIFERATORS	29	5
4768	6	11268 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(43):27988-27997 Hsu MH; Palmer CNA; Song W; Griffin KJ; Johnson EF A carboxyl-terminal extension of the zinc finger domain contributes to the specificity and polarity of peroxisome proliferator-activated receptor DNA binding	25	3
4769	9	12521 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(30):27950-27958 Hsu MH; Savas V; Griffin KJ; Johnson EF Identification of peroxisome proliferator-responsive human genes by elevated expression of the peroxisome proliferator- activated receptor a in HepG2 cells	24	1
4770	18	11535 1999 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1430(1):95-102 Hsu NC; Guzov VM; Hsu LC; Chung BC Characterization of the consequence of a novel Glu-380 to Asp mutation by expression of functional P450c21 in Escherichia coli	2	1
4771	9	11924 2000 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 383(1):119-127 Hsu PY; Tsai AL; Wang LH Identification of thromboxane synthase amino acid residues involved in heme-propionate binding	2	0
4772	3	9288 1994 METABOLISM-CLINICAL AND EXPERIMENTAL 43(7):913-916 HU HY; GREIF RL; GOODWIN CW THE EFFECTS OF THERMAL-INJURY ON MITOCHONDRIAL OXYGEN- CONSUMPTION AND THE GLYCEROL PHOSPHATE SHUTTLE	2	0
4773	7	11705 1999 JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 13(6):307-315 Hu K; Bunce NJ Metabolism of polychlorinated dibenzo-p-dioxins by rat liver microsomes	8	0
4774	23	11769 1999 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS 2(2):183-210 Hu KK; Bunce NJ Metabolism of polychlorinated dibenzo-p-dioxins and related dioxin-like compounds	14	0
4775	16	11637 1999 ENDOCRINOLOGY 140(12):5609-5618 Hu MC; Chou SJ; Huang YY; Hsu NC; Li H; Chung BC Tissue-specific, hormonal, and developmental regulation of SCC- LacZ expression in transgenic mice leads to adrenocortical zone characterization	14	1
4776	11	7229 1990 MOLECULAR ENDOCRINOLOGY 4(6):893-898 HU MC; CHUNG BC EXPRESSION OF HUMAN 21-HYDROXYLASE (P450C21) IN BACTERIAL AND MAMMALIAN-CELLS - A SYSTEM TO CHARACTERIZE NORMAL AND MUTANT ENZYMES	19	8
4777	9	7395 1991 BIOCHEMICAL JOURNAL 274():813-817 HU MC; GUO IC; LIN JH; CHUNG BC REGULATED EXPRESSION OF CYTOCHROME-P-450SCC (CHOLESTEROL-SIDE- CHAIN CLEAVAGE ENZYME) IN CULTURED-CELL LINES DETECTED BY ANTIBODY AGAINST BACTERIALLY EXPRESSED HUMAN PROTEIN	22	4
4778	19	10012 1996 BIOCHEMICAL JOURNAL 316():325-329 Hu MC; Hsu LC; Hsu NC; Chung BC Function and membrane topology of wild-type and mutated cytochrome P-450c21	9	4
4779	4	11505 1999 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 263(2):286-293 Hu Y; Hakkola J; Oscarson M; Ingelman-Sundberg M Structural and functional characterization of the 5 '-flanking region of the rat and human cytochrome P450 2E1 genes: Identification of a polymorphic repeat in the human gene	19	2
4780	17	10495 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 340(2):208-214 Hua ZC; Zhang QY; Su T; Lipinskas TW; Ding XX cDNA cloning, heterologous expression, and characterization of mouse CYP2G1, an olfactory-specific steroid hydroxylase	11	10
4781	3	8090 1992 EUROPEAN JOURNAL OF PHARMACOLOGY 211(3):359-364 HUANG HC; CHANG JH; TUNG SF; WU RT; FOEGH ML; CHU SH IMMUNOSUPPRESSIVE EFFECT OF EMODIN, A FREE-RADICAL GENERATOR	21	0
4782	3	7576 1991 EUROPEAN JOURNAL OF PHARMACOLOGY 205(3):289-294 HUANG HC; LEE CR; CHAO PDL; CHEN CC; CHU SH VASORELAXANT EFFECT OF EMODIN, AN ANTHRAQUINONE FROM A CHINESE HERB	13	1
4783	6	11601 1999 DRUG METABOLISM AND DISPOSITION 27(1):98-101 Huang JD; Guo WC; Lai MD; Guo YL; Lambert GH Detection of a novel cytochrome P-450 1A2 polymorphism (F21L) in Chinese	18	3
4784	5	1213 1970 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 41(3):737-& HUANG JJ; KIMURA T DOES REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE HAVE A DUAL FUNCTION IN STEROID HYDROXYLATION REACTIONS IN ADRENAL MITOCHONDRIA	10	9
4785	5	1471 1971 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 44(5):1065-& HUANG JJ; KIMURA T SPECIFIC ROLE OF REDUCED ADRENODOXIN IN ADRENAL MITOCHONDRIAL STEROID HYDROXYLASES	10	7
4786	4	2120 1973 BIOCHEMISTRY 12(3):406-409 HUANG JJ; KIMURA T STUDIES ON ADRENAL STEROID HYDROXYLASES - OXIDATION-REDUCTION PROPERTIES OF ADRENAL IRON-SULFUR PROTEIN (ADRENODOXIN)	93	37
4787	1	2573 1974 JOURNAL OF NEUROCHEMISTRY 23(2):393-404 HUANG M; DALY JW INTERRELATIONSHIPS AMONG LEVELS OF ATP, ADENOSINE AND CYCLIC- AMP IN INCUBATED SLICES OF GUINEA-PIG CEREBRAL-CORTEX - EFFECTS OF DEPOLARIZING AGENTS, PSYCHOTROPIC-DRUGS AND METABOLIC- INHIBITORS	61	0
4788	17	12460 2001 ENDOCRINOLOGY 142(6):2569-2576 Huang MC; Miller WL Creation and activity of COS-1 cells stably expressing the F2 fusion of the human cholesterol side-chain cleavage enzyme system	1	0
4789	15	4395 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256(13):6829-6836 HUANG MT; CHANG RL; FORTNER JG; CONNEY AH STUDIES ON THE MECHANISM OF ACTIVATION OF MICROSOMAL BENZO[A]PYRENE HYDROXYLATION BY FLAVONOIDS	88	36
4790	15	4384 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256(21):897-901 HUANG MT; JOHNSON EF; MULLEREBERHARD U; KOOP DR; COON MJ; CONNEY AH SPECIFICITY IN THE ACTIVATION AND INHIBITION BY FLAVONOIDS OF BENZO[ALPHA]PYRENE HYDROXYLATION BY CYTOCHROME-P-450 ISOZYMES FROM RABBIT LIVER-MICROSOMES	108	0
4791	16	3132 1976 JOURNAL OF BIOLOGICAL CHEMISTRY 251(15):4659-4665 HUANG MT; WEST SB; LU AYH SEPARATION, PURIFICATION, AND PROPERTIES OF MULTIPLE FORMS OF CYTOCHROME-P-450 FROM LIVER-MICROSOMES OF PHENOBARBITAL-TREATED MICE	181	54
4792	8	12116 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(4):2852-2858 Huang NW; Miller WL Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc	16	2
4793	7	7908 1992 BIOCHEMICAL PHARMACOLOGY 43(3):637-639 HUANG S; GIBSON GG SPECIES AND CONGENER SPECIFIC INDUCTION OF HEPATIC CYTOCHROME P4504A BY POLYCHLORINATED-BIPHENYLS	7	1
4794	4	12730 2002 BIOPHYSICAL JOURNAL 82(5):2811-2825 Huang SH; Heikal AA; Webb WW Two-photon fluorescence spectroscopy and microscopy of NAD(P)H and flavoprotein	4	0
4795	10	7787 1991 TOXICOLOGY AND APPLIED PHARMACOLOGY 108(1):86-95 HUANG SW; GIBSON GG DIFFERENTIAL INDUCTION OF CYTOCHROMES-P450 AND CYTOCHROME-P450- DEPENDENT ARACHIDONIC-ACID METABOLISM BY 3,4,5,3',4'- PENTACHLOROBIPHENYL IN THE RAT AND THE GUINEA-PIG	20	7
4796	2	11291 1998 JOURNAL OF LEUKOCYTE BIOLOGY 64(3):322-330 Huang YI; Surichamorn W; Cao GL; Meng M; Pou S; Rosen GM; Salcedo TW; Strimpler A; Veale C; Bernstein PR; Bonuccelli CM Effect of trifluoromethyl ketone-based elastase inhibitors on neutrophil function in vitro	5	0
4797	16	10156 1996 DRUG METABOLISM AND DISPOSITION 24(8):899-905 Huang ZQ; Fasco MJ; Figge HL; Keyomarsi K; Kaminsky LS Expression of cytochromes P450 in human breast tissue and tumors	67	17
4798	9	10503 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 343(1):101-108 Huang ZQ; Fasco MJ; Kaminsky LS Alternative splicing of CYP2D mRNA in human breast tissue	11	6
4799	9	11104 1998 CARCINOGENESIS 19(5):867-872 Huang ZQ; Guengerich FP; Kaminsky LS 16 alpha-hydroxylation of estrone by human cytochrome P4503A4/5	17	5
4800	4	4369 1981 ISOTOPENPRAXIS 17(4):167-170 HUBNER G EFFECT OF HEAVY-WATER ON ISOLATED RAT-LIVER MITOCHONDRIA	1	0

#	Cited nodes	Nodes / Authors	GCS	LCS
4801	19	11923 2000 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 383(1):70-78 Hudecek J; Anzenbacherova E; Anzenbacher P; Munro AW; Hildebrandt P Structural similarities and differences of the heme pockets of various P450 isoforms as revealed by resonance Raman spectroscopy	2	0
4802	8	11007 1998 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 243(3):811-815 Hudeeek J; Baumruk V; Anzenbacher P; Munro AW Catalytically self-sufficient P450 CYP102 (cytochrome P450 BM- 3): Resonance Raman spectral characterization of the heme domain and of the holoenzyme	5	3
4803	10	12399 2001 CARCINOGENESIS 22(5):763-770 Hudson CE; Schulte BA; Sutter TR; Norris JS Steroid hormones modulate expression of cytochrome P450 enzymes in male hamster reproductive tract and leiomyosarcomas	1	0
4804	5	3153 1976 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 7(4):255-262 HUDSON RW; SCHACHTER H; KILLINGER DW STUDIES OF 11-BETA-HYDROXYLATION BY BEEF ADRENAL MITOCHONDRIA	11	2
4805	3	10403 1996 PSYCHOPHARMACOLOGY BULLETIN 32(2):259-263 Hudziak JJ; Geller B Interethnic psychopharmacologic research in children and adolescents	2	0
4806	11	10827 1997 MOLECULAR CARCINOGENESIS 20(2):224-230 Hukkanen J; Hakkola J; Anttila S; Piipari R; Karjalainen A; Pelkonen O; Raunio H Detection of mRNA encoding xenobiotic-metabolizing cytochrome P450s in human bronchoalveolar macrophages and peripheral blood lymphocytes	40	11
4807	19	11899 2000 AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 22(3):360-366 Hukkanen J; Lassila A; Paivarinta K; Valanne S; Sarpo S; Hakkola J; Pelkonen O; Raunio H Induction and regulation of xenobiotic-metabolizing cytochrome P450s in the human A549 lung adenocarcinoma cell line	19	7
4808	7	11372 1998 PHARMACOLOGY & TOXICOLOGY 82(2):93-97 Hukkanen J; Mantyla M; Kangas L; Wirta P; Hakkola J; Paakki P; Evisalmi S; Pelkonen O; Raunio H Expression of cytochrome P450 genes encoding enzymes active in the metabolism of tamoxifen in human uterine endometrium	13	1
4809	52	12756 2002 CRITICAL REVIEWS IN TOXICOLOGY 32(5):391-411 Hukkanen J; Pelkonen A; Hakkola J; Raunio H Expression and regulation of xenobiotic-metabolizing cytochrome P450 (CYP) enzymes in human lung	2	0
4810	21	12480 2001 EUROPEAN RESPIRATORY JOURNAL 18():122S-126S Hukkanen J; Pelkonen O; Raunio H Expression of xenobiotic-metabolizing enzymes in human pulmonary tissue: possible role in susceptibility for ILD	2	0
4811	9	12233 2000 PROTEIN EXPRESSION AND PURIFICATION 18(3):310-315 Hull AK; Celenza JL Bacterial expression and purification of the Arabidopsis NADPH- cytochrome P450 reductase ATR2	0	0
4812	2	12226 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(5):2379-2384 Hull AK; Vij R; Celenza JL Arabidopsis cytochrome P450s that catalyze the first step of tryptophan-dependent indole-3-acetic acid biosynthesis	52	2
4813	7	3324 1977 CLINICAL BIOCHEMISTRY 10(2):83-88 HULL EW; PASEMAN FH ETHANOL-HOST INTERACTIONS DETERMINED BY RADIO-RESPIROMETRY OF C-14 GLUCOSES	2	0
4814	7	6461 1989 BIOCHEMISTRY 28(11):4871-4879 HULLA JE; JUCHAU MR OCCURRENCE AND INDUCIBILITY OF CYTOCHROME-P450IIIA IN MATERNAL AND FETAL RATS DURING PRENATAL DEVELOPMENT	27	15
4815	7	6572 1989 DRUG METABOLISM REVIEWS 20(2-4):765-779 HULLA JE; JUCHAU MR DEVELOPMENTAL ASPECTS OF P450IIIA - PRENATAL ACTIVITY AND INDUCIBILITY	10	5
4816	9	9603 1995 DNA AND CELL BIOLOGY 14(5):451-463 HUM DW; AZABLANC P; MILLER WL CHARACTERIZATION OF PLACENTAL TRANSCRIPTIONAL ACTIVATION OF THE HUMAN GENE FOR P450SCC	19	3
4817	2	4402 1981 JOURNAL OF ENDOCRINOLOGY 91(3):447-456 HUM WT; BARTABARTOVA A; BIRMINGHAM MK STEROIDOGENIC AND GLYCOLYTIC RESPONSES TO NUCLEOTIDES, NUCLEOSIDES AND STEROIDS IN RODENT ADRENAL-GLANDS - OPPOSING, SPECIES-DEPENDENT EFFECTS OF CYCLIC-GMP	3	0
4818	14	5123 1984 EUROPEAN JOURNAL OF BIOCHEMISTRY 140(3):583-591 HUME R; KELLY RW; TAYLOR PL; BOYD GS THE CATALYTIC CYCLE OF CYTOCHROME-P-450SCC AND INTERMEDIATES IN THE CONVERSION OF CHOLESTEROL TO PREGNENOLONE	41	7
4819	4	11039 1998 BIOCHEMISTRY 37(2):552-557 Humphries KM; Yoo Y; Szweda LI Inhibition of NADH-linked mitochondrial respiration by 4- hydroxy-2-nonenal	47	0
4820	10	10732 1997 INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 27(5):377-385 Hung CF; Berenbaum MR; Schuler MA Isolation and characterization of CYP6B4, a furanocoumarin- inducible cytochrome P450 from a Polyphagous caterpillar (Lepidoptera: Papilionidae)	18	7
4821	19	10395 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(22):12200-12205 Hung CF; Holzmacher R; Connolly E; Berenbaum MR; Schuler MA Conserved promoter elements in the CYP6B gene family suggest common ancestry for cytochrome P450 monooxygenases mediating furanocoumarin detoxification	26	7
4822	16	7923 1992 BIOCHEMICAL PHARMACOLOGY 44(2):275-283 HUNT CM; WESTERKAM WR; STAVE GM EFFECT OF AGE AND GENDER ON THE ACTIVITY OF HUMAN HEPATIC-CYP3A	125	20
4823	3	5211 1984 METHODS IN ENZYMOLOGY 107():413-438 HUNT S HALOGENATED TYROSINE DERIVATIVES IN INVERTEBRATE SCLEROPROTEINS - ISOLATION AND IDENTIFICATION	9	0
4824	4	66 1959 JOURNAL OF BIOLOGICAL CHEMISTRY 234(8):2176-2186 HUNTER FE; LEVY JF; FINK J; SCHUTZ B; GUERRA F; HURWITZ A STUDIES ON THE MECHANISM BY WHICH ANAEROBIOSIS PREVENTS SWELLING OF MITOCHONDRIA INVITRO - EFFECT OF ELECTRON TRANSPORT CHAIN INHIBITORS	133	5
4825	4	12564 2001 JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 24(4):299-302 Hunter RP; Short CR; Dees AA Interaction of cimetidine with equine hemoglobin	0	0
4826	5	11802 1999 MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS 443(1-2):235-249 Hursting SD; Kari FW The anti-carcinogenic effects of dietary restriction: mechanisms and future directions	15	1
4827	3	11767 1999 JOURNAL OF THE NATIONAL CANCER INSTITUTE 91(3):215-225 Hursting SD; Slaga TJ; Fischer SM; DiGiovanni J; Phang JM Mechanism-based cancer prevention approaches: Targets, examples, and the use of transgenic mice	36	0
4828	2	8198 1992 JOURNAL OF CLINICAL INVESTIGATION 89(6):1746-1754 HURWITZ A; LOUKIDES J; RICCIARELLI E; BOTERO L; KATZ E; MCALLISTER JM; GARCIA JE; ROHAN R; ADASHI EY; HERNANDEZ ER HUMAN INTRAOVARIAN INTERLEUKIN-1 (IL-1) SYSTEM - HIGHLY COMPARTMENTALIZED AND HORMONALLY DEPENDENT REGULATION OF THE GENES ENCODING IL-1, ITS RECEPTOR, AND ITS RECEPTOR ANTAGONIST	106	1
4829	15	9375 1994 TOXICOLOGY AND APPLIED PHARMACOLOGY 129(2):294-308 HUSOY AM; MYERS MS; WILLIS ML; COLLIER TK; CELANDER M; GOKSOYR A IMMUNOHISTOCHEMICAL LOCALIZATION OF CYP1A-LIKE AND CYP3A-LIKE ISOZYMES IN HEPATIC AND EXTRAHEPATIC TISSUES OF ATLANTIC COD (GADUS-MORHUA L), A MARINE FISH	52	14
4830	12	10342 1996 MOLECULAR MARINE BIOLOGY AND BIOTECHNOLOGY 5(1):84-92 Husoy AM; Straetkvern KO; Maaseide NP; Olsen SO; Goksoyr A Polyclonal and monoclonal antibodies against immunoaffinity- purified Atlantic cod (Gadus morhua L) CYP1A	13	2
4831	17	11262 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(26):16155-16162 Huss JM; Kasper CB Nuclear receptor involvement in the regulation of rat cytochrome P450 3A23 expression	29	12
4832	15	12188 2000 MOLECULAR PHARMACOLOGY 58(1):48-57 Huss JM; Kasper CB Two-stage glucocorticoid induction of CYP3A23 through both the glucocorticoid and pregnane X receptors	13	7
4833	7	8888 1994 AMERICAN JOURNAL OF PHYSIOLOGY 266(1):C243-C253 HUSSAIN H; SHORNICK LP; SHANNON VR; WILSON JD; FUNK CD; PENTLAND AP; HOLTZMAN MJ EPIDERMIS CONTAINS PLATELET-TYPE 12-LIPOXYGENASE THAT IS OVEREXPRESSED IN GERMINAL LAYER KERATINOCYTES IN PSORIASIS	58	0
4834	7	11750 1999 JOURNAL OF PATHOLOGY 188(2):197-200 Hutson JL; Wickramasinghe SN Expression of CYP2E1 by human monocyte-derived macrophages	2	1
4835	4	1382 1970 LIFE SCIENCES PT-2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY 9(15):877-& HUTTERER F; DENK H; BACCHIN PG; SCKENKMA.JB; SCHAFFNE.F; POPPER H MECHANISM OF CHOLESTASIS .1. EFFECT OF BILE ACIDS ON MICROSOMAL CYTOCHROME-P-450 DEPENDENT BIOTRANSFORMATION SYSTEM IN-VITRO	90	20
4836	4	1136 1969 LABORATORY INVESTIGATION 20(5):455-& HUTTERER F; KLION FM; WENGRAF A; SCHAFFNE.F; POPPER H HEPATOCELLULAR ADAPTATION AND INJURY - STRUCTURAL AND BIOCHEMICAL CHANGES FOLLOWING DIELDRIN AND METHYL BUTTER YELLOW	121	23
4837	24	12775 2002 DRUG METABOLISM AND DISPOSITION 30(4):355-362 Hutzler JM; Tracy TS Atypical kinetic profiles in drug metabolism reactions	5	2
4838	9	13023 2003 CHEMICAL RESEARCH IN TOXICOLOGY 16(4):450-459 Hutzler JM; Walker GS; Wienkers LC Inhibition of cytochrome P450 2D6: Structure-activity studies using a series of quinidine and quinine analogues	0	0
4839	4	8082 1992 EUROPEAN JOURNAL OF BIOCHEMISTRY 207(1):229-238 HUWYLER J; AESCHLIMANN D; CHRISTEN U; GUT J THE KIDNEY AS A NOVEL TARGET TISSUE FOR PROTEIN ADDUCT FORMATION ASSOCIATED WITH METABOLISM OF HALOTHANE AND THE CANDIDATE CHLOROFLUOROCARBON REPLACEMENT 2,2-DICHLORO-1,1,1- TRIFLUOROETHANE	24	1
4840	7	8079 1992 EUROPEAN JOURNAL OF BIOCHEMISTRY 206(3):869-879 HUWYLER J; JEDLITSCHKY G; KEPPLER D; GUT J HALOTHANE METABOLISM - IMPAIRMENT OF HEPATIC OMEGA-OXIDATION OF LEUKOTRIENES INVIVO AND INVITRO	10	5
4841	3	2389 1974 ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE 211(2):269-279 HUYEN HT; MULLER D; LUBBE H; KLINGER W EFFECT OF CHLORAMPHENICOL ON BIOTRANSFORMATION REACTIONS	2	0
4842	2	2750 1975 BIOCHIMIE 57(5):529-537 HUYNH CH MECHANISTIC STUDIES ON YEAST C-NITROSO-REDUCTASE	2	0
4843	2	11469 1999 ANTICANCER RESEARCH 19(3A):2095-2099 Huynh HT; Teel RW Effects of intragastrically administered Pycnogenol (R) on NNK metabolism in F344 rats	4	0
4844	5	12687 2002 ANTICANCER RESEARCH 22(3):1699-1703 Huynh HT; Teel RW Effects of plant-derived phenols on rat liver cytochrome p450 2B1 activity	1	0
4845	4	9993 1996 ARCHIVES OF TOXICOLOGY 70(10):640-644 Hwang JM; Tseng TH; Hsieh YS; Chou FP; Wang CJ; Chu CY Inhibitory effect of atractylon on tert-butyl hydroperoxide induced DNA damage and hepatic toxicity in rat hepatocytes	5	0
4846	9	8269 1992 MOLECULAR PHARMACOLOGY 41(2):259-266 HYLAND R; GESCHER A; THUMMEL K; SCHILLER C; JHEETA P; MYNETT K; SMITH AW; MRAZ J METABOLIC OXIDATION AND TOXIFICATION OF N-METHYLFORMAMIDE CATALYZED BY THE CYTOCHROME P450 ISOENZYME CYP2E1	30	6
4847	6	8716 1993 JOURNAL OF INVESTIGATIVE DERMATOLOGY 101(1):59-63 IANNONE A; MARCONI A; ZAMBRUNO G; GIANNETTI A; VANNINI V; TOMASI A FREE-RADICAL PRODUCTION DURING METABOLISM OF ORGANIC HYDROPEROXIDES BY NORMAL HUMAN KERATINOCYTES	12	0
4848	8	5956 1987 MUTATION RESEARCH 182(5):231-241 IBA MM COMPARATIVE ACTIVATION OF 3,3'-DICHLOROBENZIDINE AND RELATED BENZIDINES TO MUTAGENS IN THE SALMONELLA-TYPHIMURIUM ASSAY BY HEPATIC S9 AND MICROSOMES FROM RATS PRETREATED WITH DIFFERENT INDUCERS OF CYTOCHROME-P-450	12	1
4849	17	11492 1999 ARCHIVES OF TOXICOLOGY 73(4-5):208-216 Iba MM; Fung J; Thomas PE; Park Y Constitutive and induced expression by pyridine and beta- naphthoflavone of rat CYP1A is sexually dimorphic	4	0
4850	22	8878 1993 XENOBIOTICA 23(3):227-239 IBA MM; GANDER JE; MANNERING GJ LIPID PEROXIDATION-CYTOCHROME P450 INTERACTIONS - USE OF LINOLEIC-ACID HYDROPEROXIDE IN THE CHARACTERIZATION OF THE SPIN-STATE OF MEMBRANE-BOUND P450	3	1
4851	6	6073 1988 BIOCHEMICAL PHARMACOLOGY 37(5):781-791 IBA MM; LANG B STIMULATION OF THE CONJUGATION OF LIPID DIENES IN HEPATIC MICROSOMES BY 3,3'-DICHLOROBENZIDINE	9	1
4852	11	12694 2002 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 404(2):326-334 Iba MM; Nguyen T; Fung J CYP1A1 induction by pyridine and its metabolites in HepG2 cells	0	0
4853	20	4783 1983 BIOCHEMICAL PHARMACOLOGY 32(5):901-909 IBA MM; SIKKA HC INDUCTION OF HEPATIC-MICROSOMAL CYTOCHROME-P-448-MEDIATED OXIDASES BY 3,3'-DICHLOROBENZIDINE IN THE RAT	13	4
4854	18	3441 1977 MOLECULAR PHARMACOLOGY 13(6):1092-1104 IBA MM; SOYKA LF; SCHULMAN MP CHARACTERISTICS OF LIVER MICROSOMAL DRUG-METABOLIZING ENZYME- SYSTEM OF NEWBORN RATS	37	7
4855	10	11297 1998 JOURNAL OF NEUROSCIENCE RESEARCH 54(3):402-411 Ibach B; Appel K; Gebicke-Haerter P; Meyer RP; Friedberg T; Knoth R; Volk B Effect of phenytoin on cytochrome P450 2B mRNA expression in primary rat astrocyte cultures	7	2
4856	27	10241 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(21):12496-12501 Ibeanu GC; Ghanayem BI; Linko P; Li LP; Pedersen LG; Goldstein JA Identification of residues 99, 220, and 221 of human cytochrome P450 2C19 as key determinants of omeprazole hydroxylase activity	41	19
4857	17	9510 1995 BIOCHEMISTRY 34(25):8028-8036 IBEANU GC; GOLDSTEIN JA TRANSCRIPTIONAL REGULATION OF HUMAN CYP2C GENES - FUNCTIONAL COMPARISON OF CYP2C9 AND CYP2C18 PROMOTER REGIONS	24	17
4858	1	5354 1985 CHEMICAL & PHARMACEUTICAL BULLETIN 33(1):451-453 IBUKA T; CHU GN; AOYAGI T; KITADA K; TSUKIDA T; YONEDA F A CONVENIENT LEWIS ACID-CATALYZED PREPARATION OF CARBAMATES FROM SECONDARY ALCOHOLS AND ISOCYANATES	7	0
4859	5	1030 1969 BIOCHIMICA ET BIOPHYSICA ACTA 176(4):704-& ICHIHARA K; KUSUNOSE E; KUSUNOSE M SOME PROPERTIES AND DISTRIBUTION OF OMEGA-HYDROXYLATION SYSTEM OF MEDIUM-CHAIN FATTY ACIDS	80	28
4860	5	1102 1969 JOURNAL OF BIOCHEMISTRY 65(4):597-& ICHII S; YAGO N HORMONAL REGULATION OF AMINOPYRINE N-DEMETHYLASE SYSTEM IN RAT LIVER	13	5
4861	35	4454 1981 SEIKAGAKU 53(4):221-245 ICHIKAWA Y CYTOCHROME P-450-LINKED MIXED-FUNCTION OXIDASE SYSTEMS (MONO- OXYGENASES) OF MICROSOMAL AND MITOCHONDRIAL TYPES AND THEIR SUBSTRATE SPECIFICITIES	4	0
4862	5	585 1967 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 120(1):204-& ICHIKAWA Y; HAGIHARA B; YAMANO T MAGNETIC AND SPECTROPHOTOMETRIC PROPETIES OF MICROSOMAL CARBON MONOXIDE BINDING PIGMENT	29	17
4863	6	1360 1970 JOURNAL OF CELL BIOLOGY 45(3):640-& ICHIKAWA Y; KURODA M; YAMANO T ZONATION OF HEMOPROTEIN P-450 AND CYTOCHROME B5 IN ADRENOCORTEX OF MAMMALS	26	11
4864	3	1764 1972 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 46(3):1187-& ICHIKAWA Y; LOEHR JS NADH-DEPENDENT CYTOCHROME-P-450 OXIDASE SYSTEM IN SUBMICROSOMAL PARTICLES	30	22
4865	2	367 1965 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 20(3):263-& ICHIKAWA Y; YAMANO T CYTOCHROME 559 IN MICROSOMES OF ADRENAL MEDULLA	20	1
4866	2	593 1967 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 121(3):742-& ICHIKAWA Y; YAMANO T ELECTRON SPIN RESONANCE OF MICROSOMAL CYTOCHROMES - CORRELATION OF AMOUNT OF CO-BINDING SPECIES WITH SO-CALLED MICROSOMAL FEX IN MICROSOMES OF NORMAL TISSUES AND LIVER MICROSOMES OF SUDAN 3-TREATED ANIMALS	54	27
4867	7	656 1967 BIOCHIMICA ET BIOPHYSICA ACTA 147(3):518-& ICHIKAWA Y; YAMANO T ROLE OF HYDROPHOBIC BONDING IN P-450 AND EFFECT OF ORGANIC COMPOUNDS ON CONVERSION OF P-450 TO P-420	47	15
4868	28	3691 1978 SEIKAGAKU 50(2):77-86 ICHIKAWA Y; YAMANO T PROBLEMS OF RECONSTITUTION OF CYTOCHROME P-450-LINKED MIXED- FUNCTION OXIDASE SYSTEM	1	1
4869	14	1025 1969 BIOCHIMICA ET BIOPHYSICA ACTA 171(1):32-& ICHIKAWA Y; YAMANO T; FUJISHIM.H RELATIONSHIP BETWEEN INTERCONVERSION OF CYTOCHROME P-450 AND P- 420 AND ITS ACTIVITIES IN HYDROXYLATIONS AND DEMETHYLATIONS BY P-450 OXIDASE SYSTEMS	63	30
4870	7	12690 2002 APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 58(1):97-105 Ichinose H; Wariishi H; Tanaka H Identification and characterization of novel cytochrome P450 genes from the white-rot basidiomycete, Coriolus versicolor	7	0
4871	1	1184 1970 AGRICULTURAL AND BIOLOGICAL CHEMISTRY 34(5):715-& IDA S; KITAMURA I; MORITA Y STUDIES ON RESPIRATORY ENZYMES IN RICE KERNEL .3. PHYSICOCHEMICAL AND ENZYMATIC PROPERTIES OF PEROXIDASE-556 FROM RICE EMBRYO	4	0
4872	2	8609 1993 ENVIRONMENTAL HEALTH PERSPECTIVES 101():117-120 IDLE JR; DALY AK NEW OPPORTUNITIES IN CANCER RISK-EVALUATION USING PCR-BASED DNA ANALYSIS FOR CYP2D6	3	0
4873	12	10489 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 339(1):85-91 Igarashi T; Sakuma T; Isogai M; Nagata R; Kamataki T Marmoset liver cytochrome P450s: Study for expression and molecular cloning of their cDNAs	10	5
4874	6	6535 1989 CIRCULATION RESEARCH 65(1):1-21 IGNARRO LJ BIOLOGICAL ACTIONS AND PROPERTIES OF ENDOTHELIUM-DERIVED NITRIC-OXIDE FORMED AND RELEASED FROM ARTERY AND VEIN	765	0
4875	4	5450 1985 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 233(3):560-569 IGNARRO LJ; HARBISON RG; WOOD KS; WOLIN MS; MCNAMARA DB; HYMAN AL; KADOWITZ PJ DIFFERENCES IN RESPONSIVENESS OF INTRAPULMONARY ARTERY AND VEIN TO ARACHIDONIC-ACID - MECHANISM OF ARTERIAL RELAXATION INVOLVES CYCLIC GUANOSINE 3'-5'-MONOPHOSPHATE AND CYCLIC ADENOSINE 3'- 5'-MONOPHOSPHATE	64	3
4876	6	11958 2000 BIOCHEMISTRY 39(20):5961-5970 Ihara M; Takahashi S; Ishimori K; Morishima I Functions of fluctuation in the heme-binding loops of cytochrome b(5) revealed in the process of heme incorporation	6	0
4877	5	3095 1976 FEBS LETTERS 64(1):111-115 IHLEFELD H; DIEHL H ELEMENTARY TURNOVER MEASUREMENTS ON MONO-OXYGENASE SYSTEM FROM LIVER-MICROSOMES - MEASUREMENT OF INITIAL KINETICS	5	4
4878	5	12081 2000 FISHERIES SCIENCE 66(2):358-364 Iijima N; Chosa S; Hada T; Kayama M Identification of 12-lipoxygenase products in the gills of carp, Cyprinus carpio	3	0
4879	3	10202 1996 FISHERIES SCIENCE 62(1):114-121 Iijima N; Hada T; Kayama M Production of monohydroxy derivatives from highly unsaturated fatty acids in the gills of red sea bream Pagrus major	2	1
4880	7	2902 1975 SEIKAGAKU 47(12):1061-1090 IIZUKA T PHYSICAL ENZYMOLOGY	1	0
4881	14	12183 2000 MOLECULAR AND CELLULAR ENDOCRINOLOGY 164(1-2):169-181 Ijiri S; Berard C; Trant JM Characterization of gonadal and extra-gonadal forms of the cDNA encoding the Atlantic stingray (Dasyatis sabina) cytochrome P450 aromatase (CYP19)	5	0
4882	11	1909 1972 JAPANESE JOURNAL OF PHARMACOLOGY 22(4):479-& IKEDA M; IMAMURA T; OHTSUJI H COMPARATIVE STUDIES ON ANILINE HYDROXYLATION AND PARA- NITROTOLUENE HYDROXYLATION BY LIVER	9	0
4883	5	12799 2002 ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 11(1):1-7 Ikeda M; Inukai N; Mitsui T; Sone H; Yonemoto J; Tohyama C; Tomita T Changes in fetal brain aromatase activity following in utero 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure in rats	0	0
4884	4	9296 1994 MOLECULAR ENDOCRINOLOGY 8(5):654-662 IKEDA Y; SHEN WH; INGRAHAM HA; PARKER KL DEVELOPMENTAL EXPRESSION OF MOUSE STEROIDOGENIC FACTOR-I, AN ESSENTIAL REGULATOR OF THE STEROID HYDROXYLASES	255	14
4885	6	7573 1991 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 16(1):1-7 IKEDIOBI CO; KWANASHIE HO; OSUIDE G; WAMBEBE C EFFECTS OF CIMETIDINE ON DRUG-METABOLISM IN RAT PUPS	0	0
4886	1	10936 1997 ZYGOTE 5(2):153-175 Ikegami R; RiveraBennetts AK; Brooker DL; Yager TD Effect of inhibitors of DNA replication on early zebrafish embryos: evidence for coordinate activation of multiple intrinsic cell-cycle checkpoints at the mid-blastula transition	8	0
4887	11	11785 1999 MOLECULAR AND CELLULAR BIOCHEMISTRY 198(1-2):89-100 Ikegwuonu FI; Jefcoate CR Evidence for the involvement of the fatty acid and peroxisomal beta-oxidation pathways in the inhibition by dehydroepiandrosterone (DHEA) and induction by 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) and benz(a) anthracene (BA) of cytochrome P4501B1 (CYP1B1) in mouse embryo fibroblasts (C3H10T1/2 cells)	5	0
4888	3	6983 1990 CARCINOGENESIS 11(11):1927-1935 IKEGWUONU FI; PAI JK; MUELLER GC EFFECTS OF STEROIDS ON THE SYNTHESIS AND METABOLISM OF PHOSPHATIDYLETHANOL IN PHORBOL ESTER-ACTIVATED LYMPHOCYTES	3	1
4889	13	7918 1992 BIOCHEMICAL PHARMACOLOGY 43(11):2407-2412 IKEMOTO S; IMAOKA S; HAYAHARA N; MAEKAWA M; FUNAE Y EXPRESSION OF HEPATIC-MICROSOMAL CYTOCHROME-P450S AS ALTERED BY UREMIA	4	0
4890	8	6705 1989 MOLECULAR ENDOCRINOLOGY 3(9):1399-1408 IKEYA K; JAISWAL AK; OWENS RA; JONES JE; NEBERT DW; KIMURA S HUMAN CYP1A2 - SEQUENCE, GENE STRUCTURE, COMPARISON WITH THE MOUSE AND RAT ORTHOLOGOUS GENE, AND DIFFERENCES IN LIVER 1A2 MESSENGER-RNA EXPRESSION	79	26
4891	6	1403 1970 PLANT PHYSIOLOGY 45(6):773-& IKUMA H NECESSARY CONDITIONS FOR ISOLATION OF TIGHTLY COUPLED HIGHER PLANT MITOCHONDRIA	33	3
4892	8	726 1967 PLANT PHYSIOLOGY 42(11):1535-& IKUMA H; BONNER WD PROPERTIES OF HIGHER PLANT MITOCHONDRIA .3. EFFECTS OF RESPIRATORY INHIBITORS	81	21
4893	2	3185 1976 PLANT PHYSIOLOGY 58(3):320-323 IKUMA H; TETLEY RM POSSIBLE INTERFERENCE BY AN ACID-STABLE ENZYME DURING EXTRACTION OF NUCLEOSIDE DIPHOSPHATES AND TRIPHOSPHATES FROM HIGHER PLANT-TISSUES	11	0
4894	4	3390 1977 JOURNAL OF BIOCHEMISTRY 82(6):1741-1749 IKUTA S; IMAMURA S; MISAKI H; HORIUTI Y PURIFICATION AND CHARACTERIZATION OF CHOLINE-OXIDASE FROM ARTHROBACTER-GLOBIFORMIS	90	1
4895	4	2625 1974 TOXICOLOGY AND APPLIED PHARMACOLOGY 28(2):216-226 ILETT KF; STRIPP B; MENARD RH; REID WD; GILLETTE JR STUDIES ON MECHANISM OF LUNG TOXICITY OF PARAQUAT - COMPARISON OF TISSUE DISTRIBUTION AND SOME BIOCHEMICAL PARAMETERS IN RATS AND RABBITS	150	5
4896	20	2443 1974 BIOCHEMICAL PHARMACOLOGY 23(18):2603-2616 ILLING HPA; KUNKE S; NETTER KJ SPECTRAL INTERMEDIATE AT 440 NM FORMED DURING MIXED-FUNCTION SUBSTRATE OXIDATION	5	3
4897	13	2916 1975 XENOBIOTICA 5(1):1-15 ILLING HPA; NETTER KJ EFFECTS OF SULFHYDRYL REAGENTS ON BINDING AND MIXED-FUNCTION OXIDATION OF HEXOBARBITAL IN RAT HEPATIC MICROSOMES	9	0
4898	1	2597 1974 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 282():R37-R37 ILLING HPA; PUHALLA G; NETTER KJ ROLE OF SULFHYDRYL GROUPS IN MICROSOMAL MIXED-FUNCTION OXIDATION OF DRUGS	1	1
4899	4	5610 1986 CHEMICAL & PHARMACEUTICAL BULLETIN 34(10):4287-4293 IMAI K; AIMOTO T; SATO M; WATANABE K; KIMURA R; MURATA T EFFECTS OF SODIUM METALLOCHLOROPHYLLINS ON THE ACTIVITY AND COMPONENTS OF THE MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM IN RAT-LIVER	14	0
4900	4	866 1968 JOURNAL OF BIOCHEMISTRY 63(2):207-& IMAI K; ASANO A; SATO R OXIDATIVE PHOSPHORYLATION IN MICROCOCCUS DENITRIFICANS .4. FURTHER CHARACTERIZATION OF ELECTRON-TRANSFER PATHWAY AND PHOSPHORYLATION ACTIVITY IN NADH OXIDATION	28	5

#	Cited nodes	Nodes / Authors	GCS	LCS
4901	3	867 1968 JOURNAL OF BIOCHEMISTRY 63(2):219-& IMAI K; ASANO A; SATO R OXIDATIVE PHOSPHORYLATION IN MICROCOCCUS DENITRIFICANS .V. EFFECTS OF IRON DEFICIENCY ON RESPIRATORY COMPONENTS AND OXIDATIVE PHOSPHORYLATION	19	7
4902	2	9283 1994 MAMMALIAN GENOME 5():S139-S153 IMAI K; KINGSLEY DM MOUSE CHROMOSOME-9	16	0
4903	4	12994 2003 BIOCHEMICAL PHARMACOLOGY 65(10):1583-1591 Imai K; Kudo N; Koyama M; Kawashima Y Effects of dehydroepiandrosterone on oleic acid accumulation in rat liver	0	0
4904	6	6754 1989 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 86(20):7823-7827 IMAI M; SHIMADA H; WATANABE Y; MATSUSHIMAHIBIYA Y; MAKINO R; KOGA H; HORIUCHI T; ISHIMURA Y UNCOUPLING OF THE CYTOCHROME P-450CAM MONOOXYGENASE REACTION BY A SINGLE MUTATION, THREONINE-252 TO ALANINE OR VALINE - A POSSIBLE ROLE OF THE HYDROXY AMINO-ACID IN OXYGEN ACTIVATION	197	77
4905	20	8697 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(26):19681-19689 IMAI T; GLOBERMAN H; GERTNER JM; KAGAWA N; WATERMAN MR EXPRESSION AND PURIFICATION OF FUNCTIONAL HUMAN 17-ALPHA- HYDROXYLASE/17,20-LYASE (P450C17) IN ESCHERICHIA-COLI - USE OF THIS SYSTEM FOR STUDY OF A NOVEL FORM OF COMBINED 17-ALPHA- HYDROXYLASE/17,20-LYASE DEFICIENCY	96	46
4906	4	7048 1990 ENDOCRINOLOGY 127(4):1742-1747 IMAI T; SEO H; MURATA Y; OHNO M; SATOH Y; FUNAHASHI H; TAKAGI H; MATSUI N ADRENOCORTICOTROPIN INCREASES EXPRESSION OF C-FOS AND BETA- ACTIN GENES IN THE RAT ADRENALS	31	1
4907	6	7176 1990 JOURNAL OF MOLECULAR ENDOCRINOLOGY 4(3):239-245 IMAI T; SEO H; MURATA Y; OHNO M; SATOH Y; FUNAHASHI H; TAKAGI H; MATSUI N ALTERATION IN THE EXPRESSION OF GENES FOR CHOLESTEROL SIDE- CHAIN CLEAVAGE ENZYME AND 21-HYDROXYLASE BY HYPOPHYSECTOMY AND ACTH ADMINISTRATION IN THE RAT ADRENAL	14	1
4908	4	8137 1992 HUMAN GENETICS 89(1):95-96 IMAI T; YANASE T; WATERMAN MR; SIMPSON ER; PRATT JJ CANADIAN MENNONITES AND INDIVIDUALS RESIDING IN THE FRIESLAND REGION OF THE NETHERLANDS SHARE THE SAME MOLECULAR-BASIS OF 17- ALPHA-HYDROXYLASE DEFICIENCY	13	5
4909	8	3118 1976 JOURNAL OF BIOCHEMISTRY 80(2):267-276 IMAI Y USE OF 8-AMINOOCTYL SEPHAROSE FOR SEPARATION OF SOME COMPONENTS OF HEPATIC MICROSOMAL ELECTRON-TRANSFER SYSTEM	106	34
4910	18	4375 1981 JOURNAL OF BIOCHEMISTRY 89(2):351-362 IMAI Y THE ROLES OF CYTOCHROME-B5 IN RECONSTITUTED MONO-OXYGENASE SYSTEMS CONTAINING VARIOUS FORMS OF HEPATIC-MICROSOMAL CYTOCHROME-P-450	73	43
4911	16	4631 1982 JOURNAL OF BIOCHEMISTRY 92(1):77-88 IMAI Y INTERACTION OF POLYCYCLIC-HYDROCARBONS WITH CYTOCHROME-P-450 .3. EFFECTS OF HYDROCARBON BINDING ON THE INTERACTION OF SOME LIGANDS WITH P-4481 HEME	23	7
4912	20	9014 1994 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1207(1):49-57 IMAI Y; FUKUDA T; KOMORI M; NAKAMURA M COMPARISON OF HEME ENVIRONMENT AT THE PUTATIVE DISTAL REGION OF P-450S UTILIZING THEIR EXTERNAL AND INTERNAL NITROGENOUS LIGAND BOUND FORMS	7	6
4913	9	4630 1982 JOURNAL OF BIOCHEMISTRY 92(1):67-75 IMAI Y; IIZUKA T; ISHIMURA Y INTERACTION OF POLYCYCLIC-HYDROCARBONS WITH CYTOCHROME-P-450 .2. FLASH-PHOTOLYSIS STUDIES ON VARIOUS HYDROCARBON-BOUND P- 4481 CO COMPOUNDS	12	7
4914	6	6106 1988 BIOCHEMISTRY 27(1):80-88 IMAI Y; KOMORI M; SATO R COMPARISON OF PRIMARY STRUCTURES DEDUCED FROM CDNA NUCLEOTIDE- SEQUENCES FOR VARIOUS FORMS OF LIVER MICROSOMAL CYTOCHROME-P- 450 FROM PHENOBARBITAL-TREATED RABBITS	38	28
4915	13	12113 2000 JOURNAL OF BIOCHEMISTRY 128(2):189-194 Imai Y; Matsunaga I; Kusunose E; Ichihara K Unique heme environment at the putative distal region of hydrogen peroxide-dependent fatty acid alpha-hydroxylase from Sphingomonas paucimobilis (Peroxygenase P450(SP alpha))	3	1
4916	7	7613 1991 JOURNAL OF BIOCHEMISTRY 110(6):884-888 IMAI Y; NAKAMURA M NITROGENOUS LIGATION AT THE 6TH COORDINATION POSITION OF THE THR-301 TO LYS-MUTATED P450IIC2 HEME IRON	8	7
4917	18	10577 1997 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1337(1):66-74 Imai Y; Okamoto N; Nakahara K; Shoun H Absorption spectral studies on heme ligand interactions of P- 450(nor)	6	4
4918	4	468 1966 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 22(6):620-& IMAI Y; SATO R SUBSTRATE INTERACTION WITH HYDROXYLASE SYSTEM IN LIVER MICROSOMES	204	187
4919	2	469 1966 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 23(1):5-& IMAI Y; SATO R EVIDENCE FOR 2 FORMS OF P-450 HEMOPROTEIN IN MICROSOMAL MEMBRANES	159	100
4920	5	476 1966 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 25(1):80-& IMAI Y; SATO R ACTIVATION AND INHIBITION OF MICROSOMAL HYDROXYLATION BY ETHYL ISOCYANIDE	77	39
4921	7	666 1967 EUROPEAN JOURNAL OF BIOCHEMISTRY 1(4):419-& IMAI Y; SATO R CONVERSION OF P-450 TO P-420 BY NEUTRAL SALTS AND SOME OTHER REAGENTS	175	89
4922	9	683 1967 JOURNAL OF BIOCHEMISTRY 62(2):239-& IMAI Y; SATO R STUDIES ON SUBSTRATE INTERACTIONS WITH P-450 IN DRUG HYDROXYLATION BY LIVER MICROSOMES	165	136
4923	11	685 1967 JOURNAL OF BIOCHEMISTRY 62(4):464-& IMAI Y; SATO R ANOMALOUS SPECTRAL INTERACTIONS OF REDUCED P-450 WITH ETHYL ISOCYANIDE AND SOME OTHER LIPOPHILIC LIGANDS	81	56
4924	9	868 1968 JOURNAL OF BIOCHEMISTRY 63(2):270-& IMAI Y; SATO R EFFECT OF IONIC STRENGTH ON ETHYL ISOCYANIDE DIFFERENCE SPECTRUM OF REDUCED P-450 IN LIVER MICROSOMES	29	17
4925	11	870 1968 JOURNAL OF BIOCHEMISTRY 63(3):370-& IMAI Y; SATO R BEHAVIOR OF 2 STATES OF ETHYL ISOCYANIDE COMPOUND OF REDUCED P- 450 IN OXIDATION-REDUCTION CYCLE	17	14
4926	12	871 1968 JOURNAL OF BIOCHEMISTRY 63(3):380-& IMAI Y; SATO R DUAL EFFECT OF ETHYL ISOCYANIDE ON DRUG HYDROXYLATION BY LIVER MICROSOMES	23	20
4927	5	2417 1974 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 60(1):8-14 IMAI Y; SATO R GEL-ELECTROPHORETICALLY HOMOGENEOUS PREPARATION OF CYTOCHROME- P-450 FROM LIVER-MICROSOMES OF PHENOBARBITAL-PRETREATED RABBITS	334	115
4928	8	3259 1977 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 75(2):420-426 IMAI Y; SATO R ROLES OF CYTOCHROME B5 IN A RECONSTITUTED N-DEMETHYLASE SYSTEM CONTAINING CYTOCHROME-P-450	98	73
4929	15	3389 1977 JOURNAL OF BIOCHEMISTRY 82(5):1237-1246 IMAI Y; SATO R; IYANAGI T RATE-LIMITING STEP IN RECONSTITUTED MICROSOMAL DRUG HYDROXYLASE SYSTEM	56	41
4930	21	1446 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 144(1):143-& IMAI Y; SIEKEVIT.P COMPARISON OF SOME PROPERTIES OF MICROSOMAL CYTOCHROME P-450 FROM NORMAL, METHYLCHOLANTHRENE-TREATED, AND PHENOBARBITAL- TREATED RATS	49	27
4931	7	7117 1990 JOURNAL OF BIOCHEMISTRY 108(4):522-524 IMAI Y; UNO T; NAKAMURA M CHARACTERIZATION OF RABBIT LIVER P450IIE1 SYNTHESIZED IN TRANSFORMED YEAST-CELLS	15	14
4932	6	9530 1995 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1246(1):53-60 IMAISHI H; YAMADA T; OHKAWA H PURIFICATION AND IMMUNOCHEMICAL CHARACTERISTICS OF NADPH- CYTOCHROME P-450 OXIDOREDUCTASE FROM TOBACCO CULTURED-CELLS	7	5
4933	4	8728 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 264(1):166-171 IMAMURA Y; IWAMOTO K; YANACHI Y; HIGUCHI T; OTAGIRI M POSTNATAL-DEVELOPMENT, SEX-RELATED DIFFERENCE AND HORMONAL- REGULATION OF ACETOHEXAMIDE REDUCTASE ACTIVITIES IN RAT-LIVER AND KIDNEY	23	1
4934	5	7185 1990 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 255(3):1385-1391 IMAOKA S; ENOMOTO K; ODA Y; ASADA A; FUJIMORI M; SHIMADA T; FUJITA S; GUENGERICH FP; FUNAE Y LIDOCAINE METABOLISM BY HUMAN CYTOCHROME-P-450S PURIFIED FROM HEPATIC MICROSOMES - COMPARISON OF THOSE WITH RAT HEPATIC CYTOCHROME-P-450S	112	41
4935	12	7460 1991 BIOCHIMICA ET BIOPHYSICA ACTA 1097(3):187-192 IMAOKA S; FUJITA S; FUNAE Y AGE-DEPENDENT EXPRESSION OF CYTOCHROME-P-450S IN RAT-LIVER	54	14
4936	9	7115 1990 JOURNAL OF BIOCHEMISTRY 108(1):33-36 IMAOKA S; FUNAE Y PURIFICATION AND CHARACTERIZATION OF RAT PULMONARY CYTOCHROME- P-450	15	9
4937	11	7416 1991 BIOCHEMICAL PHARMACOLOGY 42():S143-S150 IMAOKA S; FUNAE Y INDUCTION OF CYTOCHROME P450 ISOZYMES IN RAT-LIVER BY METHYL NORMAL-ALKYL KETONES AND NORMAL-ALKYLBENZENES - EFFECTS OF HYDROPHOBICITY OF INDUCERS ON INDUCIBILITY OF CYTOCHROME P450	20	10
4938	19	7449 1991 BIOCHIMICA ET BIOPHYSICA ACTA 1074(1):209-213 IMAOKA S; FUNAE Y HEPATIC AND RENAL CYTOCHROME-P-450S IN SPONTANEOUSLY HYPERTENSIVE RATS	30	19
4939	14	12346 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 284(3):757-762 Imaoka S; Hayashi K; Hiroi T; Yabusaki Y; Kamataki T; Funae Y A transgenic mouse expressing human CYP4B1 in the liver	7	2
4940	8	9449 1995 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 321(1):255-262 IMAOKA S; HIROI T; TAMURA Y; YAMAZAKI H; SHIMADA T; KOMORI N; DEGAWA M; FUNAE Y MUTAGENIC ACTIVATION OF 3-METHOXY-4-AMINOAZOBENZENE BY MOUSE RENAL CYTOCHROME-P450 CYP4B1 - CLONING AND CHARACTERIZATION OF MOUSE CYP4B1	16	10
4941	8	8286 1992 MUTATION RESEARCH 269(2):231-236 IMAOKA S; IKEMOTO S; SHIMADA T; FUNAE Y MUTAGENIC ACTIVATION OF AFLATOXIN-B1 BY PULMONARY, RENAL, AND HEPATIC CYTOCHROME-P450S FROM RATS	17	5
4942	18	6037 1988 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 265(1):159-170 IMAOKA S; INOUE K; FUNAE Y AMINOPYRINE METABOLISM BY MULTIPLE FORMS OF CYTOCHROME-P-450 FROM RAT-LIVER MICROSOMES - SIMULTANEOUS QUANTITATION OF 4 AMINOPYRINE METABOLITES BY HIGH-PERFORMANCE LIQUID- CHROMATOGRAPHY	44	20
4943	13	8483 1993 BIOCHEMICAL PHARMACOLOGY 46(12):2197-2200 IMAOKA S; NAKAMURA M; ISHIZAKI T; SHIMOJO N; OHISHI N; FUJII S; FUNAE Y REGULATION OF RENAL CYTOCHROME P450S BY THYROID-HORMONE IN DIABETIC RATS	9	4
4944	15	8585 1993 DNA AND CELL BIOLOGY 12(10):893-899 IMAOKA S; OGAWA H; KIMURA S; GONZALEZ FJ COMPLETE CDNA SEQUENCE AND CDNA-DIRECTED EXPRESSION OF CYP4A11, A FATTY-ACID OMEGA-HYDROXYLASE EXPRESSED IN HUMAN KIDNEY	38	25
4945	7	8546 1993 CARCINOGENESIS 14(1):117-121 IMAOKA S; SUGIYAMA T; TANIGUCHI N; FUNAE Y EXPRESSION OF CYTOCHROME P450 IN LEC RATS DURING THE DEVELOPMENT OF HEREDITARY HEPATITIS AND HEPATOMA	5	1
4946	13	6475 1989 BIOCHEMISTRY INTERNATIONAL 18(4):731-740 IMAOKA S; TANAKA S; FUNAE Y OMEGA-HYDROXYLATION AND (OMEGA-1)-HYDROXYLATION OF LAURIC ACID AND ARACHIDONIC-ACID BY RAT RENAL CYTOCHROME-P-450	38	25
4947	15	6626 1989 JOURNAL OF BIOCHEMISTRY 105(6):939-945 IMAOKA S; TERANO Y; FUNAE Y EXPRESSION OF 4 PHENOBARBITAL-INDUCIBLE CYTOCHROME-P-450S IN LIVER, KIDNEY, AND LUNG OF RATS	73	33
4948	10	8737 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 267(2):1012-1016 IMAOKA S; WEDLUND PJ; OGAWA H; KIMURA S; GONZALEZ FJ; KIM HY IDENTIFICATION OF CYP2C23 EXPRESSED IN RAT-KIDNEY AS AN ARACHIDONIC-ACID EPOXYGENASE	26	18
4949	11	6933 1990 BIOCHIMICA ET BIOPHYSICA ACTA 1036(1):18-23 IMAOKA S; YAMAGUCHI Y; FUNAE Y INDUCTION AND REGULATION OF CYTOCHROME P450.K-5 (LAURIC ACID HYDROXYLASE) IN RAT RENAL MICROSOMES BY STARVATION	31	15
4950	16	7885 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 299(1):179-184 IMAOKA S; YAMAZOE Y; KATO R; FUNAE Y HORMONAL-REGULATION OF RAT RENAL CYTOCHROME-P450S BY ANDROGEN AND THE PITUITARY	26	11
4951	8	10555 1997 BIOCHEMICAL PHARMACOLOGY 54(6):677-683 Imaoka S; Yoneda Y; Matsuda T; Degawa M; Fukushima S; Funae Y Mutagenic activation of urinary bladder carcinogens by CYP4B1 and the presence of CYP4BI in bladder mucosa	11	2
4952	7	9803 1995 MARINE POLLUTION BULLETIN 30(8):558-562 IMBER BE; SPENCE B; CHAN Z; VANAGGELEN G TEMPORAL VARIATION IN HEPATIC MIXED-FUNCTION OXIDASE (MFO) INDUCTION IN RAINBOW-TROUT EXPOSED TO INDUSTRIAL EFFLUENT	1	0
4953	19	11897 2000 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 279(6):F965-F981 Imig JD Eicosanoid regulation of the renal vasculature	27	3
4954	65	12185 2000 MOLECULAR BIOTECHNOLOGY 16(3):233-251 Imig JD Epoxygenase metabolites - Epithelial and vascular actions	3	0
4955	6	8652 1993 HYPERTENSION 22(3):357-364 IMIG JD; FALCK JR; GEBREMEDHIN D; HARDER DR; ROMAN RJ ELEVATED RENOVASCULAR TONE IN YOUNG SPONTANEOUSLY HYPERTENSIVE RATS - ROLE OF CYTOCHROME-P-450	55	12
4956	11	12830 2002 HYPERTENSION 39(2):690-694 Imig JD; Zhao XY; Capdevila JH; Morisseau C; Hammock BD Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension	9	3
4957	6	12544 2001 JOURNAL OF HYPERTENSION 19(5):983-992 Imig JD; Zhao XY; Falck JR; Wei SZ; Capdevila JH Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12- epoxyeicosatrienoic acid	5	1
4958	4	1045 1969 BIOCHIMICA ET BIOPHYSICA ACTA 191(2):257-& INANO H; INANO A; TAMAOKI BI SUBMICROSOMAL DISTRIBUTION OF ADRENAL ENZYMES AND CYTOCHROME P- 450 RELATED TO CORTICOIDOGENESIS	43	13
4959	1	1175 1969 STEROIDS 13(3):357-& INANO H; MACHINO A; TAMAOKI BI LOCALIZATION OF DELTA5-3BETA-HYDROXYSTEROID DEHYDROGENASE AND 21-HYDROXYLASE ACTIVITIES IN SMOOTH-SURFACED MICROSOMES OF ADRENALS	22	1
4960	7	11857 1999 TOXICOLOGICAL SCIENCES 52(1):130-139 Inder RE; Bray BJ; Sipes IG; Rosengren RJ Role of cytochrome P4502E1 in retinol's attenuation of carbon tetrachloride-induced hepatotoxicity in the Swiss Webster mouse	3	0
4961	14	12100 2000 INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH 73(2):71-85 Indulski JA; Lutz W Metabolic genotype in relation to individual susceptibility to environmental carcinogens	4	1
4962	5	426 1965 JOURNAL OF BIOLOGICAL CHEMISTRY 240(10):3996-& INFANTE AA; DAVIES RE EFFECT OF 2,4-DINITROFLUOROBENZENE ON ACTIVITY OF STRIATED MUSCLE	85	3
4963	2	377 1965 BIOCHIMICA ET BIOPHYSICA ACTA 94(2):504-& INFANTE AA; KLAUPIKS D; DAVIES RE PHOSPHORYLCREATINE CONSUMPTION DURING SINGLE-WORKING CONTRACTIONS OF ISOLATED MUSCLE	29	5
4964	11	4863 1983 EUROPEAN JOURNAL OF BIOCHEMISTRY 134(1):157-162 INGELMANSUNDBERG M; BLANCK J; SMETTAN G; RUCKPAUL K REDUCTION OF CYTOCHROME-P-450 LM2 BY NADPH IN RECONSTITUTED PHOSPHOLIPID-VESICLES IS DEPENDENT ON MEMBRANE CHARGE	24	0
4965	7	10003 1996 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 221(2):318-322 IngelmanSundberg M; Hagbjork AL; Ueng YF; Yamazaki H; Guengerich FP High rates of substrate hydroxylation by human cytochrome p450 3A4 in reconstituted membranous vesicles: Influence of membrane charge	26	19
4966	13	4009 1980 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 97(2):582-589 INGELMANSUNDBERG M; JOHANSSON I CYTOCHROME-B5 AS ELECTRON-DONOR TO RABBIT LIVER CYTOCHROME-P- 450LM2 IN RECONSTITUTED PHOSPHOLIPID-VESICLES	68	0
4967	12	4044 1980 BIOCHEMISTRY 19(17):4004-4011 INGELMANSUNDBERG M; JOHANSSON I CATALYTIC PROPERTIES OF PURIFIED FORMS OF RABBIT LIVER MICROSOMAL CYTOCHROME-P-450 IN RECONSTITUTED PHOSPHOLIPID- VESICLES	45	0
4968	17	5012 1984 ACTA CHEMICA SCANDINAVICA SERIES B-ORGANIC CHEMISTRY AND BIOCHEMISTRY 38(10):845-851 INGELMANSUNDBERG M; JOHANSSON I ELECTRON FLOW AND COMPLEX-FORMATION DURING CYTOCHROME-P-450- CATALYZED HYDROXYLATION REACTIONS IN RECONSTITUTED MEMBRANE- VESICLES	2	0
4969	15	5178 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259(10):6447-6458 INGELMANSUNDBERG M; JOHANSSON I MECHANISMS OF HYDROXYL RADICAL FORMATION AND ETHANOL OXIDATION BY ETHANOL-INDUCIBLE AND OTHER FORMS OF RABBIT LIVER MICROSOMAL CYTOCHROMES-P-450	192	0
4970	13	3633 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253(14):5042-5047 INGELMANSUNDBERG M; MONTELIUS J; RYDSTROM J; GUSTAFSSON JA ACTIVE FORM OF CYTOCHROME-P-45011-BETA FROM ADRENAL-CORTEX MITOCHONDRIA	16	7
4971	15	2963 1976 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 174(1):298-304 INGLEDEW WJ; SALERNO JC; OHNISHI T THERMODYNAMIC RESOLUTION OF CYTOCHROME-P450 AND CHARACTERIZATION OF AN IRON-SULFUR CENTER IN RAT-LIVER MICROSOMAL PREPARATIONS	6	2
4972	4	7650 1991 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 73(4):717-726 INKSTER SE; BRODIE AMH EXPRESSION OF AROMATASE CYTOCHROME-P-450 IN PREMENOPAUSAL AND POSTMENOPAUSAL HUMAN OVARIES - AN IMMUNOCYTOCHEMICAL STUDY	62	9
4973	12	11938 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 269(2):623-627 Inoue E; Takahashi Y; Imai Y; Kamataki T Development of bacterial expression system with high yield of CYP3A7, a human fetus-specific form of cytochrome P450	2	2
4974	15	12269 2000 XENOBIOTICA 30(3):285-295 Inoue K; Asao T; Shimada T Ethnic-related differences in the frequency distribution of genetic polymorphisms in the CYP1A1 and CYP1B1 genes in Japanese and Caucasian populations	15	2
4975	3	8144 1992 JAPANESE JOURNAL OF HUMAN GENETICS 37(2):133-138 INOUE K; INAZAWA J; NAKAGAWA H; SHIMADA T; YAMAZAKI H; GUENGERICH FP; ABE T ASSIGNMENT OF THE HUMAN CYTOCHROME-P-450 NIFEDIPINE OXIDASE GENE (CYP3A4) TO CHROMOSOME-7 AT BAND Q22.1 BY FLUORESCENCE INSITU HYBRIDIZATION	19	10
4976	8	9169 1994 JAPANESE JOURNAL OF HUMAN GENETICS 39(3):337-343 INOUE K; INAZAWA J; SUZUKI Y; SHIMADA T; YAMAZAKI H; GUENGERICH FP; ABE T FLUORESCENCE IN-SITU HYBRIDIZATION ANALYSIS OF CHROMOSOMAL LOCALIZATION OF 3 HUMAN CYTOCHROME-P450-2C GENES (CYP2C8, 2C9, AND 2C10) AT 10Q24.1	5	3
4977	17	10855 1997 PHARMACOGENETICS 7(2):103-113 Inoue K; Yamazaki H; Imiya K; Akasaka S; Guengerich FP; Shimada T Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4'-hydroxylation activities in livers of Japanese and Caucasian populations	73	26
4978	11	11430 1998 XENOBIOTICA 28(4):403-411 Inoue K; Yamazaki H; Shimada T Linkage between the distribution of mutations in the CYP2C18 and CYP2C19 genes in the Japanese and Caucasian	6	0
4979	5	11078 1998 BREEDING SCIENCE 48(2):135-143 Inui H; Shiota N; Ishige T; Ohkawa Y; Ohkawa H Herbicide metabolism and resistance of transgenic potato plants expressing rat cytochrome P4501A1	12	2
4980	5	11812 1999 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 64(1):33-46 Inui H; Ueyama Y; Shiota N; Okhawa Y; Ohkawa H Herbicide metabolism and cross-tolerance in transgenic potato plants expressing human CYP1A1	15	2
4981	11	5357 1985 CHEMICO-BIOLOGICAL INTERACTIONS 53(3):303-311 IOANNIDES C; DELAFORGE M; PARKE DV INTERACTIONS OF SAFROLE AND ISOSAFROLE AND THEIR METABOLITES WITH CYTOCHROMES-P-450	10	2
4982	12	2923 1975 XENOBIOTICA 5(11):665-676 IOANNIDES C; LAKE BG; PARKE DV ENHANCEMENT OF HEPATIC MICROSOMAL DRUG-METABOLISM INVITRO FOLLOWING ETHANOL ADMINISTRATION	7	4
4983	25	5252 1984 XENOBIOTICA 14(1-2):119-137 IOANNIDES C; LUM PY; PARKE DV CYTOCHROME-P-448 AND THE ACTIVATION OF TOXIC-CHEMICALS AND CARCINOGENS	106	27
4984	7	2868 1975 JOURNAL OF PHARMACY AND PHARMACOLOGY 27(10):739-746 IOANNIDES C; PARKE DV MECHANISM OF INDUCTION OF HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYMES BY A SERIES OF BARBITURATES	169	24
4985	6	3045 1976 CHEMICO-BIOLOGICAL INTERACTIONS 14(3-4):241-249 IOANNIDES C; PARKE DV EFFECT OF ALLYL COMPOUNDS ON HEPATIC MICROSOMAL MIXED-FUNCTION OXIDATION AND PORPHYROGENESIS	9	4
4986	62	7036 1990 DRUG METABOLISM REVIEWS 22(1):1-85 IOANNIDES C; PARKE DV THE CYTOCHROME-P450-I GENE FAMILY OF MICROSOMAL HEMOPROTEINS AND THEIR ROLE IN THE METABOLIC-ACTIVATION OF CHEMICALS	170	50
4987	2	4574 1982 BRITISH JOURNAL OF PHARMACOLOGY 77(1):83-88 IOANNIDES C; PARKE DV; TAYLOR IW ELIMINATION OF GLYCERYL TRINITRATE - EFFECTS OF SEX, AGE, SPECIES AND ROUTE OF ADMINISTRATION	16	0
4988	9	6779 1989 TOXICOLOGY LETTERS 49(1):61-68 IOANNIDES C; RODRIGUES AD; AYRTON AD; BARNETT CR; CHOWN J; PARKE DV INDUCTION OF THE RAT HEPATIC-MICROSOMAL MIXED-FUNCTION OXIDASES BY CIMETIDINE	7	2
4989	14	3365 1977 GENERAL PHARMACOLOGY 8(4):243-249 IOANNIDES C; SWEATMAN B; RICHARDS R; PARKE DV DRUG-METABOLISM IN FERRET - EFFECTS OF AGE, SEX AND STRAIN	17	6
4990	7	4790 1983 BIOCHEMICAL PHARMACOLOGY 32(20):3103-3108 IOANNONI B; REILLY PEB; WINZOR DJ EVALUATION OF MONOOXYGENASE INDUCTION AS A MEANS OF ENHANCING THE YIELD OF THE RAT-LIVER CYTOCHROME-P-450 ISOENZYME WITH HIGH-AFFINITY FOR CIMETIDINE	9	2
4991	7	4815 1983 BIOLOGICAL TRACE ELEMENT RESEARCH 5(2):139-146 IP C INTERACTION OF SELENIUM DEFICIENCY AND FAT INTAKE IN THE REGULATION OF ENZYMES ASSOCIATED WITH PEROXIDE METABOLISM	3	1
4992	3	3384 1977 JOURNAL OF BACTERIOLOGY 132(2):398-410 IRANI MH; MAITRA PK PROPERTIES OF ESCHERICHIA-COLI MUTANTS DEFICIENT IN ENZYMES OF GLYCOLYSIS	39	1
4993	8	4298 1981 BIOCHEMICAL PHARMACOLOGY 30(19):2685-2690 IRELAND CM; HOLDER GM; RYAN AJ STUDIES IN THE METABOLISM OF CARCINOGENIC POLYCYCLIC HETEROAROMATIC-COMPOUNDS .1. THE HEPATIC-MICROSOMAL METABOLISM OF 7-METHYLBENZ[C]ACRIDINE	26	4
4994	15	10903 1997 TOXICOLOGY 117(1):13-23 Iribarne C; Dreano Y; Bardou LG; Menez JF; Berthou F Interaction of methadone with substrates of human hepatic cytochrome P450 3A4	35	3
4995	5	3688 1978 RADIATION RESEARCH 76(2):339-348 IRIE S; OKUMOTO M; TAKAMORI Y RATIO OF CYTOCHROMES IN RADIATION-INDUCED LEUKEMIA-CELLS OF MICE	0	0
4996	14	11404 1998 TOXICOLOGY 126(3):179-193 Irizar A; Ioannides C Marked inhibition of hepatic cytochrome P450 activity in cholesterol-induced atherosclerosis in rabbits	5	1
4997	25	10145 1996 DRUG METABOLISM AND DISPOSITION 24(2):164-171 Irshaid Y; Branch RA; Adedoyin A Metabolic interactions of putative cytochrome P4503A substrates with alternative pathways of dapsone metabolism in human liver microsomes	7	3
4998	1	9709 1995 INTERNATIONAL JOURNAL OF PHARMACEUTICS 113(1):25-37 IRWIN WJ; HOLBROOK PA; DEY MJ THE STABILITY OF PEPTIDES IN NASAL ENZYMATIC SYSTEMS	2	0
4999	6	1032 1969 BIOCHIMICA ET BIOPHYSICA ACTA 177(2):196-& ISAACS GH; SACKTOR B; MURPHY TA ROLE OF ALPHA-GLYCEROPHOSPHATE CYCLE IN CONTROL OF CARBOHYDRATE OXIDATION IN HEART AND IN MECHANISM OF ACTION OF THYROID HORMONE	28	4
5000	7	10051 1996 BIOCHEMISTRY-MOSCOW 61(8):1026-1033 Isaeva LV; Spiridonova VA; Lumovich D; Kovaleva IE; Chernogolov AA; Usanov AS; Luzikov VN Synthesis in Escherichia coli and some properties of a hybrid protein composed of a modified adrenodoxin reductase precursor and a shortened adrenodoxin precursor	2	1

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