| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 12001 | 16 | 12001 2000 CHEMICO-BIOLOGICAL INTERACTIONS 127(1):73-90
Narimatsu S; Kobayashi N; Masubuchi Y; Horie T; Kakegawa T; Kobayashi H; Hardwick JP; Gonzalez FJ; Shimada N; Ohmori S; Kitada M; Asaoka K; Kataoka H; Yamamoto S; Satoh T
Species difference in enantioselectivity for the oxidation of propranolol by cytochrome P450 2D enzymes | 5 | 1
|
| 12002 | 9 | 12002 2000 CHEMISTRY-A EUROPEAN JOURNAL 6(9):1531-1536
Li QS; Schwaneberg U; Fischer P; Schmid RD
Directed evolution of the fatty-acid hydyoxylase P450BM-3 into an indole-hydroxylating catalyst | 19 | 8
|
| 12003 | 7 | 12003 2000 CHEMOSPHERE 41(7):973-978
Hanioka N; Jinno H; Tanaka-Kagawa T; Nishimura T; Ando M
Interaction of bisphenol A with rat hepatic cytochrome P450 enzymes | 5 | 1
|
| 12004 | 3 | 12004 2000 CIRCULATION RESEARCH 87(7):566-573
Shinozaki K; Nishio Y; Okamura T; Yoshida Y; Maegawa H; Kojima H; Masada M; Toda N; Kikkawa R; Kashiwagi A
Oral administration of tetrahydrobiopterin prevents endothelial dysfunction and vascular oxidative stress in the aortas of insulin-resistant rats | 38 | 0
|
| 12005 | 7 | 12005 2000 CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 27(10):796-800
Buzaleh AM; Martinez MD; Batlle AMD
Relevance of cytochrome P450 levels in the actions of enflurane and isoflurane in mice: Studies on the haem pathway | 1 | 0
|
| 12006 | 34 | 12006 2000 CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 27(11):855-865
Roman RJ; Maier KG; Sun CW; Harder DR; Alonso-Galicia M
Renal and cardiovascular actions of 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids | 21 | 3
|
| 12007 | 12 | 12007 2000 CLINICAL CANCER RESEARCH 6(8):3297-3303
Kobayashi K; Mimura N; Fujii H; Minami H; Sasaki Y; Shimada N; Chiba K
Role of human cytochrome p450 3A4 in metabolism of medroxyprogesterone acetate | 7 | 5
|
| 12008 | 4 | 12008 2000 CLINICAL CHEMISTRY 46(11):1834-1836
van Schaik RHN; de Wildt SN; van Iperen NM; Uitterlinden AG; van den Anker JN; Lindemans J
CYP3A4-V polymorphism detection by PCR-restriction fragment length polymorphism analysis and its allelic frequency among 199 Dutch Caucasians | 3 | 0
|
| 12009 | 52 | 12009 2000 CLINICAL PHARMACOKINETICS 38(2):111-180
Venkatakrishnan K; von Moltke LL; Greenblatt DJ
Effects of the antifungal agents on oxidative drug metabolism - Clinical relevance | 67 | 5
|
| 12010 | 11 | 12010 2000 CLINICAL PHARMACOKINETICS 38(6):493-504
Fuhr U
Induction of drug metabolising enzymes - Pharmacokinetic and toxicological consequences in humans | 31 | 5
|
| 12011 | 25 | 12011 2000 CLINICAL PHARMACOKINETICS 39(2):127-153
Carrillo JA; Benitez J
Clinically significant pharmacokinetic interactions between dietary caffeine and medications | 8 | 0
|
| 12012 | 17 | 12012 2000 CLINICAL PHARMACOLOGY & THERAPEUTICS 67(1):48-56
Sata F; Sapone A; Elizondo G; Stocker P; Miller VP; Zheng W; Raunio H; Crespi CL; Gonzalez FJ
CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: Evidence for an allelic variant with altered catalytic activity | 69 | 17
|
| 12013 | 21 | 12013 2000 CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY 18(2):215-239
Boitier E; Beaune P
Xenobiotic-metabolizing enzymes as autoantigens in human autoimmune disorders - An update | 1 | 0
|
| 12014 | 6 | 12014 2000 CLINICAL SCIENCE 98(3):277-282
Chu ZM; Croft KD; Kingsbury DA; Falck JR; Reddy KM; Beilin LJ
Cytochrome P450 metabolites of arachidonic acid may be important mediators in angiotensin II-induced vasoconstriction in the rat mesentery in vivo | 17 | 3
|
| 12015 | 3 | 12015 2000 CLINICS IN CHEST MEDICINE 21(1):47-+
Tanoue LT
Cigarette smoking and women's respiratory health | 2 | 0
|
| 12016 | 16 | 12016 2000 COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS 65(1):122-132
Borek-Dohalska L; Hodek P; Stiborova M
New selective inhibitors of cytochrome P4502B4 and an activator of cytochrome P450 3A6 in rabbit liver microsomes | 3 | 0
|
| 12017 | 19 | 12017 2000 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 125(2):203-214
Rotchell JM; Steventon GB; Bird DJ
Catalytic properties of CYP1A isoforms in the liver of an agnathan (Lampetra fluviatilis) and two species of teleost (Pleuronectes flesus, Anguilla anguilla) | 2 | 0
|
| 12018 | 4 | 12018 2000 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 125(2):245-250
Stupans I; Kong S; Kirlich A; McKinnon RA; Murray M
Testosterone dehydrogenase activity in koala liver: characterisation of cofactor and steroid substrate differences | 1 | 1
|
| 12019 | 13 | 12019 2000 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 126(3):235-244
Sen A; Arinc E
Further immunochemical and biocatalytic characterization of CYP1A1 from feral leaping mullet liver (Liza saliens) microsomes | 2 | 2
|
| 12020 | 13 | 12020 2000 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 126(3):267-284
White RD; Shea D; Schlezinger JJ; Hahn ME; Stegeman JJ
In vitro metabolism of polychlorinated biphenyl congeners by beluga whale (Delphinapterus leucas) and pilot whale (Globicephala melas) and relationship to cytochrome P450 expression | 5 | 1
|
| 12021 | 19 | 12021 2000 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 127(2):143-152
Oka T; Fukuhara M; Ushio F; Kurose K
Molecular cloning and characterization of three novel cytochrome P450 2D isoforms, CYP2D20, CYP2D27, and CYP2D28 in the Syrian hamster (Mesocricetus auratus) | 1 | 0
|
| 12022 | 4 | 12022 2000 CRITICAL CARE MEDICINE 28(3):809-817
Shimizu H; Takahashi T; Suzuki T; Yamasaki A; Fujiwara T; Odaka Y; Hirakawa M; Fujita H; Akagi R
Protective effect of heme oxygenase induction in ischemic acute renal failure | 23 | 0
|
| 12023 | 26 | 12023 2000 CRITICAL REVIEWS IN TOXICOLOGY 30(3):287-306
Kranendonk M; Laires A; Rueff J; Estabrook RW; Vermeulen NPE
Heterologous expression of xenobiotic mammalian-metabolizing enzymes in mutagenicity tester bacteria: An update and practical considerations | 3 | 3
|
| 12024 | 80 | 12024 2000 CRITICAL REVIEWS IN TOXICOLOGY 30(4):347-570
Whyte JJ; Jung RE; Schmitt CJ; Tillitt DE
Ethoxyresorufin-O-deethylase (EROD) activity in fish as a biomarker of chemical exposure | 14 | 1
|
| 12025 | 25 | 12025 2000 CURRENT DRUG METABOLISM 1(1):67-84
Murray M
Mechanisms of inhibitory and regulatory effects of methylenedioxyphenyl compounds on cytochrome P450-dependent drug oxidation | 3 | 0
|
| 12026 | 38 | 12026 2000 CURRENT DRUG METABOLISM 1(2):107-132
Sheweita SA
Drug-metabolizing enzymes: Mechanisms and functions | 12 | 0
|
| 12027 | 14 | 12027 2000 CURRENT DRUG METABOLISM 1(4):305-331
Lin JH
Sense and nonsense in the prediction of drug-drug interactions | 5 | 0
|
| 12028 | 12 | 12028 2000 CURRENT GENETICS 37(1):65-73
Yadav JS; Loper JC
Cytochrome P450 oxidoreductase gene and its differentially terminated cDNAs from the white rot fungus Phanerochaete chrysosporium | 6 | 1
|
| 12029 | 54 | 12029 2000 CURRENT ORGANIC CHEMISTRY 4(3):263-282
Martinez CA; Stewart JD
Cytochrome P450's: Potential catalysts for asymmetric olefin epoxidations | 4 | 0
|
| 12030 | 14 | 12030 2000 CURRENT SCIENCE 79(12):1665-1671
Das S; Tyagi AK; Kaur H
Cancer modulation by glucosinolates: A review | 0 | 0
|
| 12031 | 5 | 12031 2000 DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT 125(3):63-67
Martin-Facklam M; Drewe J; Haefeli WE
Drug interactions with the cytochrome P 450 system | 8 | 0
|
| 12032 | 5 | 12032 2000 DIGESTIVE AND LIVER DISEASE 32(1):39-45
Clemente MG; De Virgiliis S
Autoantigen characterization in liver/kidney microsome positive hepatitis | 0 | 0
|
| 12033 | 15 | 12033 2000 DNA AND CELL BIOLOGY 19(5):307-317
Paquette SM; Bak S; Feyereisen R
Intron-exon organization and phylogeny in a large superfamily, the paralogous cytochrome P450 genes of Arabidopsis thaliana | 26 | 5
|
| 12034 | 2 | 12034 2000 DNA AND CELL BIOLOGY 19(6):319-329
Piletz JE; Ivanov TR; Sharp JD; Ernsberger P; Chang CH; Pickard RT; Gold G; Roth B; Zhu H; Jones JC; Baldwin J; Reis DJ
Imidazoline receptor antisera-selected (IRAS) cDNA: Cloning and characterization | 15 | 0
|
| 12035 | 31 | 12035 2000 DRUG DEVELOPMENT RESEARCH 49(1):4-16
Guengerich FP
Pharmacogenomics of cytochrome P450 and other enzymes involved in biotransformation of xenobiotics | 7 | 4
|
| 12036 | 16 | 12036 2000 DRUG METABOLISM AND DISPOSITION 28(1):73-78
Kuriya S; Ohmori S; Hino M; Ishii I; Nakamura H; Senda C; Igarashi T; Kiuchi M; Kitada M
Identification of cytochrome P-450 isoform(s) responsible for the metabolism of pimobendan in human liver microsomes | 2 | 1
|
| 12037 | 14 | 12037 2000 DRUG METABOLISM AND DISPOSITION 28(1):96-101
Harvey JL; Paine AJ; Maurel P; Wright MC
Effect of the adrenal 11-beta-hydroxylase inhibitor metyrapone on human hepatic cytochrome P-450 expression: Induction of cytochrome Pp-450 3A4 | 4 | 2
|
| 12038 | 3 | 12038 2000 DRUG METABOLISM AND DISPOSITION 28(2):131-138
Arora V; Iversen PL
Antisense oligonucleotides targeted to the p53 gene modulate liver regeneration in vivo | 11 | 0
|
| 12039 | 22 | 12039 2000 DRUG METABOLISM AND DISPOSITION 28(3):246-254
Houston JB; Kenworthy KE
In vitro-in vivo scaling of CYP kinetic data not consistent with the classical Michaelis-Menten model | 57 | 11
|
| 12040 | 23 | 12040 2000 DRUG METABOLISM AND DISPOSITION 28(3):360-366
Wang RW; Newton DJ; Liu N; Atkins WM; Lu AYH
Human cytochrome P-450 3A4: In vitro drug-drug interaction patterns are substrate-dependent | 46 | 11
|
| 12041 | 7 | 12041 2000 DRUG METABOLISM AND DISPOSITION 28(7):715-717
Schulz-Utermoehl T; Mountfield RJ; Madsen K; Jorgensen PN; Hansen KT
Selective and potent inhibition of human CYP2C19 activity by a conformationally targeted antipeptide antibody | 2 | 0
|
| 12042 | 24 | 12042 2000 DRUG METABOLISM AND DISPOSITION 28(7):718-725
Schulz-Utermoehl T; Mountfield RJ; Bywater RP; Madsen K; Jorgensen PN; Hansen KT
Structure-function analysis of human CYP3A4 using a specific proinhibitory antipeptide antibody | 1 | 0
|
| 12043 | 6 | 12043 2000 DRUG METABOLISM AND DISPOSITION 28(7):737-741
Sweeny DJ; Lynch G; Bidgood AM; Lew W; Wang KY; Cundy KC
Metabolism of the influenza neuraminidase inhibitor prodrug oseltamivir in the rat | 0 | 0
|
| 12044 | 14 | 12044 2000 DRUG METABOLISM AND DISPOSITION 28(8):905-911
Chun J; Kent UM; Moss RM; Sayre LM; Hollenberg PF
Mechanism-based inactivation of cytochromes P4502B1 and P4502B6 by 2-phenyl-2-(1-piperidinyl) propane | 10 | 1
|
| 12045 | 8 | 12045 2000 DRUG METABOLISM AND DISPOSITION 28(9):1094-1099
Coleman T; Spellman EF; Rostami-Hodjegan A; Lennard MS; Tucker GT
The 1 '-hydroxylation of rac-bufuralol by rat brain microsomes | 2 | 1
|
| 12046 | 12 | 12046 2000 DRUG METABOLISM AND DISPOSITION 28(10):1202-1209
Renwick AB; Watts PS; Edwards RJ; Barton PT; Guyonnet I; Price RJ; Tredger JM; Pelkonen O; Boobis AR; Lake BG
Differential maintenance of cytochrome P450 enzymes in cultured precision-cut human liver slices | 7 | 1
|
| 12047 | 2 | 12047 2000 DRUG METABOLISM AND DISPOSITION 28(10):1217-1221
Ng CY; Ghabrial H; Morgan DJ; Ching MS; Smallwood RA; Angus PW
Impaired elimination of propranolol due to right heart failure: Drug clearance in the isolated liver and its relationship to intrinsic metabolic capacity | 2 | 0
|
| 12048 | 12 | 12048 2000 DRUG METABOLISM AND DISPOSITION 28(11):1291-1296
Matsunaga T; Kishi N; Higuchi S; Watanabe K; Ohshima T; Yamamoto I
CYP3A4 is a major isoform responsible for oxidation of 7- hydroxy-Delta(8)-tetrahydrocannabinol to 7-oxo-Delta(8)- tetrahydrocannabinol in human liver microsomes | 4 | 1
|
| 12049 | 21 | 12049 2000 DRUG METABOLISM AND DISPOSITION 28(11):1311-1316
Xie Q; Zhang QY; Zhang Y; Su T; Gu J; Kaminsky LS; Ding XX
Induction of mouse CYP2J by pyrazole in the eye, kidney, liver, lung, olfactory mucosa, and small intestine, but not in the heart | 2 | 1
|
| 12050 | 49 | 12050 2000 DRUG METABOLISM REVIEWS 32(1):45-79
Kato R; Yamazoe Y
History of drug metabolism research in Japan | 0 | 0
|
| 12051 | 28 | 12051 2000 DRUG METABOLISM REVIEWS 32(3-4):339-361
Wrighton SA; Schuetz EG; Thummel KE; Shen DD; Korzekwa KR; Watkins PB
The human CYP3A subfamily: Practical considerations | 24 | 6
|
| 12052 | 0 | 12052 2000 ENDOCRINE RESEARCH 26(4):693-694
Bernhardt R; Estabrook RW
Steroidogenic enzymes - Session summary | 0 | 0
|
| 12053 | 11 | 12053 2000 ENDOCRINE RESEARCH 26(4):695-703
Auchus RJ; Worthy K; Geller DH; Miller WL
Probing structural and functional domains of human P450c17 | 5 | 2
|
| 12054 | 49 | 12054 2000 ENDOCRINE REVIEWS 21(3):245-291
White PC; Speiser PW
Congenital adrenal hyperplasia due to 21-hydroxylase deficiency | 93 | 1
|
| 12055 | 2 | 12055 2000 ENDOCRINOLOGY 141(4):1317-1324
Kinuta K; Tanaka H; Moriwake T; Aya K; Kato S; Seino Y
Vitamin D is an important factor in estrogen biosynthesis of both female and male gonads | 18 | 0
|
| 12056 | 9 | 12056 2000 ENDOCRINOLOGY 141(11):4100-4106
Pampori NA; Shapiro BH
Nominal growth hormone pulses in otherwise normal masculine plasma profiles induce intron retention of overexpressed hepatic CYP2C11 with associated nuclear splicing deficiency | 4 | 0
|
| 12057 | 2 | 12057 2000 ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA 29(4):789-+
White JR; Campbell RK
Dangerous and common drug interactions in patients with diabetes mellitus | 2 | 0
|
| 12058 | 2 | 12058 2000 ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 35(2):139-149
Taras-Valero D; Perin-Roussel O; Plessis MJ; Zajdela F; Perin F
Tissue-specific activities of methylated dibenzo[c,g]carbazoles in mice: Carcinogenicity, DNA adduct formation, and CYP1A induction in liver and skin | 1 | 0
|
| 12059 | 11 | 12059 2000 ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 36(2):121-126
Aryal P; Terashita T; Guengerich FP; Shimada T; Oda Y
Use of genetically engineered Salmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH- Cytochrome P450 reductase and bacterial O-acetyltransferase in SOS/umu assay | 4 | 2
|
| 12060 | 10 | 12060 2000 ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 19(11):2797-2805
Stagg RM; Rusin J; McPhail ME; McIntosh AD; Moffat CF; Craft JA
Effects of polycyclic aromatic hydrocarbons on expression of CYP1A in salmon (Salmo salar) following experimental exposure and after the Braer oil spill | 6 | 1
|
| 12061 | 9 | 12061 2000 ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 19(11):2806-2811
Drenth HJ; Van Oevelen CJC; Buitenhuis CJK; Van den Berg M
Induction of hepatic cytochrome P450 activities by toxaphene in rat and Japanese quail | 1 | 0
|
| 12062 | 13 | 12062 2000 ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 8(3):197-204
Spotti M; Maas RFM; de Nijs CM; Fink-Gremmels J
Effect of fumonisin B-1 on rat hepatic P450 system | 1 | 0
|
| 12063 | 9 | 12063 2000 ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 8(4):217-225
Nyman M; Raunio H; Pelkonen O
Expression and inducibility of members in the cytochrome P4501 (CYP1) family in ringed and grey seals from polluted and less polluted waters | 7 | 3
|
| 12064 | 8 | 12064 2000 ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 9(1-2):31-37
Asteinza J; Camacho-Carranza R; Reyes-Reyes RE; Dorado-Gonzalez V; Espinosa-Aguirre JJ
Induction of cytochrome P450 enzymes by albendazole treatment in the rat | 3 | 0
|
| 12065 | 12 | 12065 2000 EUROPEAN JOURNAL OF BIOCHEMISTRY 267(3):755-766
Banci L; Bertini I; Rosato A; Scacchieri S
Solution structure of oxidized microsomal rabbit cytochrome b(5) - Factors determining the heterogeneous binding of the heme | 15 | 3
|
| 12066 | 16 | 12066 2000 EUROPEAN JOURNAL OF BIOCHEMISTRY 267(4):963-970
Marc N; Galisteo M; Lagadic-Gossmann D; Fautrel A; Joannard F; Guillouzo A; Corcos L
Regulation of phenobarbital induction of the cytochrome P450 2b9/10 genes in primary mouse hepatocyte culture - Involvement of calcium- and cAMP-dependent pathways | 7 | 0
|
| 12067 | 3 | 12067 2000 EUROPEAN JOURNAL OF BIOCHEMISTRY 267(9):2705-2710
Baciocchi E; Gerini MF; Harvey PJ; Lanzalunga O; Mancinelli S
Oxidation of aromatic sulfides by lignin peroxidase from Phanerochaete chrysosporium | 9 | 0
|
| 12068 | 9 | 12068 2000 EUROPEAN JOURNAL OF BIOCHEMISTRY 267(10):2916-2920
Anzenbacherova E; Bec N; Anzenbacher P; Hudecek J; Soucek P; Jung C; Munro AW; Lange R
Flexibility and stability of the structure of cytochromes P450 3A4 and BM-3 | 9 | 2
|
| 12069 | 10 | 12069 2000 EUROPEAN JOURNAL OF BIOCHEMISTRY 267(23):6729-6739
Daiber A; Herold S; Schoneich C; Namgaladze D; Peterson JA; Ullrich V
Nitration and inactivation of cytochrome P450(BM-3) by peroxynitrite - Stopped-flow measurements prove ferryl intermediates | 22 | 2
|
| 12070 | 7 | 12070 2000 EUROPEAN JOURNAL OF BIOCHEMISTRY 267(24):7209-7217
Urcelay E; Jareno MA; Menaya J; Parrilla R; Ayuso MS; Martin-Requero A
Cloning and functional characterization of the 5 ' regulatory region of the human mitochondrial glycerol-3-phosphate dehydrogenase gene - Lack of 3,5,3 '-triiodothyronine responsiveness in adipose tissue | 2 | 1
|
| 12071 | 10 | 12071 2000 EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 30():14-20
Peter M; Dubuis JM
Transcription factors as regulators of steroidogenic P-450 enzymes | 1 | 0
|
| 12072 | 18 | 12072 2000 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 56(2):145-151
Martinez C; Gervasini G; Agundez JAG; Carrillo JA; Ramos SI; Garcia-Gamito FJ; Gallardo L; Benitez J
Modulation of midazolam 1-hydroxylation activity in vitro by neurotransmitters and precursors | 4 | 2
|
| 12073 | 26 | 12073 2000 EUROPEAN JOURNAL OF NUTRITION 39(6):270-276
Amet Y; Plee-Gautier E; Berthou F; Adas F; French SW
Adaptation to chronic ethanol administration emphasized by fatty acid hydroxylations in rat liver and kidney microsomes | 1 | 0
|
| 12074 | 11 | 12074 2000 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 12(2):103-110
Schellens JHM; Malingre MM; Kruijtzer CMF; Bardelmeijer HA; van Tellingen O; Schinkel AH; Beijnen JH
Modulation of oral bioavailability of anticancer drugs: from mouse to man | 10 | 0
|
| 12075 | 7 | 12075 2000 EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 49(2):129-135
Brunner LJ; Werner U; Gravenall CE
Effect of dose on cyclosporine-induced suppression of hepatic cytochrome P450 3A2 and 2C11 | 2 | 0
|
| 12076 | 7 | 12076 2000 EYE 14():422-428
Sarfarazi M; Stoilov I
Molecular genetics of primary congenital glaucoma | 17 | 1
|
| 12077 | 3 | 12077 2000 FARADAY DISCUSSIONS (116):15-22
Davis JJ; Djuricic D; Lo KKW; Wallace ENK; Wong LL; Hill HAO
A scanning tunnelling study of immobilised cytochrome P450(cam) | 13 | 0
|
| 12078 | 4 | 12078 2000 FARADAY DISCUSSIONS (116):135-153
Sadeghi SJ; Meharenna YT; Fantuzzi A; Valetti F; Gilardi G
Engineering artificial redox chains by molecular 'Lego' | 10 | 0
|
| 12079 | 8 | 12079 2000 FEBS LETTERS 486(2):173-177
Ost TWB; Miles CS; Murdoch J; Cheung YF; Reid GA; Chapman SK; Munro AW
Rational re-design of the substrate binding site of flavocytochrome P450BM3 | 5 | 4
|
| 12080 | 7 | 12080 2000 FISH PHYSIOLOGY AND BIOCHEMISTRY 22(3):199-206
Perkins EJ; DeBusk BC; Schlenk D
Isolation of a novel hepatic CYP2-related protein from channel catfish, Ictalurus punctatus | 1 | 0
|
| 12081 | 5 | 12081 2000 FISHERIES SCIENCE 66(2):358-364
Iijima N; Chosa S; Hada T; Kayama M
Identification of 12-lipoxygenase products in the gills of carp, Cyprinus carpio | 3 | 0
|
| 12082 | 4 | 12082 2000 FITOTERAPIA 71(1):25-33
Janbaz KH; Gilani AH
Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents | 1 | 0
|
| 12083 | 23 | 12083 2000 FRONTIERS IN NEUROENDOCRINOLOGY 21(1):1-56
Compagnone NA; Mellon SH
Neurosteroids: Biosynthesis and function of these novel neuromodulators | 75 | 1
|
| 12084 | 6 | 12084 2000 FUNDAMENTAL & CLINICAL PHARMACOLOGY 14(4):301-319
Benedetti MS
Enzyme induction and inhibition by new antiepileptic drugs: a review of human studies | 16 | 3
|
| 12085 | 10 | 12085 2000 FUNGAL GENETICS AND BIOLOGY 29(1):49-59
Muraguchi H; Kamada T
A mutation in the eln2 gene encoding a cytochrome P450 of Coprinus cinereus affects mushroom morphogenesis | 9 | 2
|
| 12086 | 1 | 12086 2000 GASTROENTEROLOGY 119(3):794-805
Titos E; Claria J; Bataller R; Bosch-Marce M; Gines P; Jimenez W; Arroyo V; Rivera F; Rodes J
Hepatocyte-derived cysteinyl leukotrienes modulate vascular tone in experimental cirrhosis | 7 | 0
|
| 12087 | 17 | 12087 2000 GENE 256(1-2):83-91
Leaver MJ; George SG
A cytochrome P4501B gene from a fish, Pleuronectes platessa | 0 | 0
|
| 12088 | 9 | 12088 2000 GENE 260(1-2):13-23
Finta C; Zaphiropoulos PG
The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons | 25 | 8
|
| 12089 | 10 | 12089 2000 GENERAL AND COMPARATIVE ENDOCRINOLOGY 118(1):123-133
Kazeto Y; Ijiri S; Todo T; Adachi S; Yamauchi K
Molecular cloning and characterization of Japanese eel ovarian P450c17 (CYP17) cDNA | 11 | 0
|
| 12090 | 10 | 12090 2000 GENETICA 110(3):257-265
Fogleman JC; Danielson PB
Analysis of fragment homology among DNA sequences from cytochrome P450 families 4 and 6 | 0 | 0
|
| 12091 | 2 | 12091 2000 GENOME RESEARCH 10(12):1958-1967
Del Punta K; Rothman A; Rodriguez I; Mombaerts P
Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse | 13 | 0
|
| 12092 | 4 | 12092 2000 GENOMICS 63(3):433-438
Finta C; Zaphiropoulos PG
The human CYP2C locus: A prototype for intergenic and exon repetition splicing events | 11 | 5
|
| 12093 | 3 | 12093 2000 GENOMICS 70(1):49-61
Sosinsky A; Glusman G; Lancet D
The genomic structure of human olfactory receptor genes | 18 | 1
|
| 12094 | 1 | 12094 2000 HAEMOPHILIA 6(5):487-490
Wilde JT
Protease inhibitor therapy and bleeding | 2 | 0
|
| 12095 | 9 | 12095 2000 HEPATOLOGY 32(1):49-55
Siewert E; Bort R; Kluge R; Heinrich PC; Castell J; Jover R
Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent | 17 | 0
|
| 12096 | 10 | 12096 2000 HUMAN & EXPERIMENTAL TOXICOLOGY 19(11):623-631
Gyamfi MA; Hokama N; Oppong-Boachie K; Aniya Y
Inhibitory effects of the medicinal herb, Thonningia sanguinea, on liver drug metabolizing enzymes of rats | 1 | 0
|
| 12097 | 4 | 12097 2000 HYPERTENSION 35(1):457-463
Muthalif MM; Benter IF; Khandekar Z; Gaber L; Estes A; Malik S; Parmentier JH; Manne V; Malik KU
Contribution of Ras GTPase/MAP kinase and cytochrome P450 metabolites to deoxycorticosterone-salt-induced hypertension | 10 | 2
|
| 12098 | 10 | 12098 2000 HYPERTENSION 36(4):610-616
Honeck H; Gross V; Erdmann B; Kargel E; Neunaber R; Milia AF; Schneider W; Luft FC; Schunck WH
Cytochrome P450-dependent renal arachidonic acid metabolism in desoxycorticosterone acetate-salt hypertensive mice | 7 | 2
|
| 12099 | 14 | 12099 2000 INSECT MOLECULAR BIOLOGY 9(5):441-449
Korytko PJ; MacIntyre RJ; Scott JG
Expression and activity of a house-fly cytochrome P450, CYP6D1, in Drosophila melanogaster | 0 | 0
|
| 12100 | 14 | 12100 2000 INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH 73(2):71-85
Indulski JA; Lutz W
Metabolic genotype in relation to individual susceptibility to environmental carcinogens | 4 | 1
|
| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 12101 | 3 | 12101 2000 INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS 38(1):30-34
Farker K; Lehmann MH; Kastner R; Weber J; Janitzky V; Schubert J; Hoffmann A
Analysis of point mutation in exon 2 of CYP2E1 gene in renal cell/urothelial cancer patients in comparison with control population | 5 | 0
|
| 12102 | 7 | 12102 2000 INTERNATIONAL JOURNAL OF ENVIRONMENT AND POLLUTION 13(1-6):56-91
Livingstone DR; Chipman JK; Lowe DM; Minier C; Mitchelmore CL; Moore MN; Peters LD; Pipe RK
Development of biomarkers to detect the effects of organic pollution on aquatic invertebrates: recent molecular, genotoxic, cellular and immunological studies on the common mussel (Mytilus edulis L.) and other mytilids | 12 | 0
|
| 12103 | 73 | 12103 2000 INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 198 198():109-152
Kanamura S; Watanabe J
Cell biology of cytochrome P-450 in the liver | 0 | 0
|
| 12104 | 7 | 12104 2000 ISRAEL JOURNAL OF CHEMISTRY 40(1):55-62
Stevenson JA; Jones JP; Wong LL
Mutations of phenylalanine-193 in the putative substrate access channel alter the substrate specificity of cytochrome P450(cam) | 1 | 1
|
| 12105 | 15 | 12105 2000 JAPANESE JOURNAL OF PHARMACOLOGY 82(3):232-239
Nakamura T; Okada K; Nagata K; Yamazoe Y
Intestinal cytochrome P450 and response to rifampicin in rabbits | 5 | 2
|
| 12106 | 1 | 12106 2000 JOURNAL OF ADVERTISING 29(4):41-58
Gould SJ; Gupta PB; Grabner-Krauter S
Product placements in movies: A cross-cultural analysis of Austrian, French and American consumers' attitudes toward this emerging, international promotional medium | 0 | 0
|
| 12107 | 2 | 12107 2000 JOURNAL OF ANIMAL SCIENCE 78(2):371-379
Engelbrecht Y; Herselman T; Louw A; Swart P
Investigation of the primary cause of hypoadrenocorticism in South African Angora goats (Capra aegagrus): A comparison with Boer goats (Capra hircus) and Merino sheep (Ovis aries) | 1 | 0
|
| 12108 | 4 | 12108 2000 JOURNAL OF APPLIED TOXICOLOGY 20(6):455-461
Poon R; Nadeau B; Chu I
Biochemical effects of chloral hydrate on male rats following 7-day drinking water exposure | 2 | 0
|
| 12109 | 14 | 12109 2000 JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 14(1):20-25
Korytko PJ; Quimby FW; Scott JG
Metabolism of phenanthrene by house fly CYP6D1 and dog liver cytochrome P450 | 1 | 1
|
| 12110 | 3 | 12110 2000 JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 14(6):335-345
Nicholls-Grzemski FA; Belling GB; Priestly BG; Calder IC; Burcham PC
Clofibrate pretreatment in mice confers resistance against hepatic lipid peroxidation | 1 | 0
|
| 12111 | 2 | 12111 2000 JOURNAL OF BIOCHEMISTRY 127(1):151-161
Furukawa H; Haga T
Expression of functional M-2 muscarinic acetylcholine receptor in Escherichia coli | 7 | 0
|
| 12112 | 16 | 12112 2000 JOURNAL OF BIOCHEMISTRY 127(6):1047-1052
Kikuta Y; Kusunose E; Kusunose M
Characterization of human liver leukotriene B-4 omega- hydroxylase P450 (CYP4F2) | 9 | 5
|
| 12113 | 13 | 12113 2000 JOURNAL OF BIOCHEMISTRY 128(2):189-194
Imai Y; Matsunaga I; Kusunose E; Ichihara K
Unique heme environment at the putative distal region of hydrogen peroxide-dependent fatty acid alpha-hydroxylase from Sphingomonas paucimobilis (Peroxygenase P450(SP alpha)) | 3 | 1
|
| 12114 | 10 | 12114 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(3):1966-1975
Andersen MD; Busk PK; Svendsen I; Moller BL
Cytochromes P-450 from cassava (Manihot esculenta Crantz) catalyzing the first steps in the biosynthesis of the cyanogenic glucosides linamarin and lotaustralin - Cloning, functional expression in Pichia pastoris, and substrate specificity of the isolated recombinant enzymes | 17 | 1
|
| 12115 | 41 | 12115 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(4):2312-2321
Oleksiak MF; Wu S; Parker C; Karchner SI; Stegeman JJ; Zeldin DC
Identification, functional characterization, and regulation of a new cytochrome P450 subfamily, the CYP2Ns | 10 | 4
|
| 12116 | 8 | 12116 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(4):2852-2858
Huang NW; Miller WL
Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc | 16 | 2
|
| 12117 | 44 | 12117 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(6):4118-4126
Lasker JM; Chen WB; Wolf I; Bloswick BP; Wilson PD; Powell PK
Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney - Role of CYP4F2 and CYP4A11 | 34 | 9
|
| 12118 | 14 | 12118 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(18):13362-13369
Handschin C; Meyer UA
A conserved nuclear receptor consensus sequence (DR-4) mediates transcriptional activation of the chicken CYP2H1 gene by phenobarbital in a hepatoma cell line | 18 | 4
|
| 12119 | 8 | 12119 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(22):16543-16549
Li-Hawkins J; Lund EG; Bronson AD; Russell DW
Expression cloning of an oxysterol 7 alpha-hydroxylase selective for 24-hydroxycholesterol | 25 | 0
|
| 12120 | 10 | 12120 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(22):17130-17135
Neve EPA; Ingelman-Sundberg M
Molecular basis for the transport of cytochrome P450 2E1 to the plasma membrane | 6 | 2
|
| 12121 | 12 | 12121 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(37):28873-28881
Sandberg M; Hassett C; Adman ET; Meijer J; Omiecinski CJ
Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms | 8 | 1
|
| 12122 | 6 | 12122 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(47):36637-36644
Reyland ME; Evans RM; White EK
Lipoproteins regulate expression of the steroidogenic acute regulatory protein (StAR) in mouse adrenocortical cells | 4 | 0
|
| 12123 | 20 | 12123 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(50):39734-39740
Kitazume T; Takaya N; Nakayama N; Shoun H
Fusarium oxysporum fatty-acid subterminal hydroxylase (CYP505) is a membrane-bound eukaryotic: Counterpart of Bacillus megaterium cytochrome P450BM3 | 5 | 4
|
| 12124 | 8 | 12124 2000 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 5(2):204-212
Tschirret-Guth RA; Koo LS; de Montellano PRO
Protein control of the formation and decomposition of the CYP119 and CYP101 aryl-iron complexes | 4 | 0
|
| 12125 | 13 | 12125 2000 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 5(4):422-431
Banci L; Presenti C
Perspectives in inorganic structural biology: solution structures of metalloproteins | 8 | 0
|
| 12126 | 13 | 12126 2000 JOURNAL OF BIOMEDICAL SCIENCE 7(2):144-151
Yeh JR; Hsu LC; Chung BC
Sp1-like proteins function in the transcription of human ferredoxin genes | 1 | 0
|
| 12127 | 31 | 12127 2000 JOURNAL OF BIOSCIENCE AND BIOENGINEERING 90(6):583-590
Sakaki T; Inouye K
Practical application of mammalian cytochrome P450 | 5 | 2
|
| 12128 | 19 | 12128 2000 JOURNAL OF BIOTECHNOLOGY 84(3):249-257
Schwaneberg U; Appel D; Schmitt J; Schmid RD
P450 in biotechnology: zinc driven omega-hydroxylation of p- nitrophenoxydodecanoic acid using P450BM-3 F87A as a catalyst | 11 | 6
|
| 12129 | 5 | 12129 2000 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 35(2):227-233
Satake N; Imanishi M; Keto Y; Yamada H; Ishikawa M; Shibata S
Genistein potentiates the relaxation induced by beta(1)- and beta(2)-adrenoceptor activation in rat aortic rings | 3 | 0
|
| 12130 | 14 | 12130 2000 JOURNAL OF CELLULAR BIOCHEMISTRY 76(4):686-694
LaBella FS; Queen GM; Brandes LJ
Interactive binding at cytochrome P-450 of cell growth regulatory bioamines, steroid hormones, antihormones, and drugs | 3 | 0
|
| 12131 | 7 | 12131 2000 JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY 75(10):933-941
Souter A; McLean KJ; Smith WE; Munro AW
The genome sequence of Mycobacterium tuberculosis reveals cytochromes P450 as novel anti-TB drug targets | 5 | 2
|
| 12132 | 1 | 12132 2000 JOURNAL OF CHROMATOGRAPHY B 737(1-2):119-130
Begum RR; Newbold RJ; Whitford D
Purification of the membrane binding domain of cytochrome b(5) by immobilised nickel chelate chromatography | 4 | 0
|
| 12133 | 3 | 12133 2000 JOURNAL OF CHROMATOGRAPHY B 741(2):145-153
Madani S; Howald WN; Lawrence RF; Shen DD
Analysis of hydroxylated and N-dealkylated metabolites of terfenadine in microsomal incubates by liquid chromatography- mass spectrometry | 1 | 0
|
| 12134 | 3 | 12134 2000 JOURNAL OF CHROMATOGRAPHY B 744(2):399-406
Hanioka N; Tatarazako N; Jinno H; Arizono K; Ando M
Determination of cytochrome P450 1A activities in mammalian liver microsomes by high-performance liquid chromatography with fluorescence detection | 5 | 1
|
| 12135 | 3 | 12135 2000 JOURNAL OF CHROMATOGRAPHY B 746(2):331-338
Bendriss EK; Markoglou N; Wainer IW
Liquid chromatographic method for the simultaneous determination of caffeine and fourteen caffeine metabolites in urine | 6 | 0
|
| 12136 | 7 | 12136 2000 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 85(6):2304-2311
Wickenheisser JK; Quinn PG; Nelson VL; Legro RS; Strauss JF; McAllister JM
Differential activity of the cytochrome P450 17 alpha- hydroxylase and steroidogenic acute regulatory protein gene promoters in normal and polycystic ovary syndrome theca cells | 16 | 1
|
| 12137 | 1 | 12137 2000 JOURNAL OF CLINICAL MICROBIOLOGY 38(4):1609-1614
Posteraro B; Sanguinetti M; Masucci L; Romano L; Morace G; Fadda G
Reverse cross blot hybridization assay for rapid detection of PCR-amplified DNA from Candida species, Cryptococcus neoformans, and Saccharomyces cerevisiae in clinical samples | 6 | 0
|
| 12138 | 12 | 12138 2000 JOURNAL OF CLINICAL ONCOLOGY 18(11):2301-2308
Yamamoto N; Tamura T; Kamiya Y; Sekine I; Kunitoh H; Saijo N
Correlation between docetaxel clearance and estimated cytochrome P450 activity by urinary metabolite of exogenous cortisol | 7 | 0
|
| 12139 | 4 | 12139 2000 JOURNAL OF FOOD AND DRUG ANALYSIS 8(3):166-173
Chang HC; Seng JE; Leakey JEA; Gandy J
Metabolism of flutamide in diet control Fischer 344 and Brown Norway x F 344 rats, and its hydroxylation and conjugation by human CYP450s and UDP-glucuronosyltransferases | 0 | 0
|
| 12140 | 7 | 12140 2000 JOURNAL OF HEPATOLOGY 33(2):216-223
Krahenbuhl L; Ledermann M; Lang C; Krahenbuhl S
Relationship between hepatic mitochondrial functions in vivo and in vitro in rats with carbon tetrachloride-induced liver cirrhosis | 3 | 0
|
| 12141 | 11 | 12141 2000 JOURNAL OF INORGANIC BIOCHEMISTRY 81(3):153-160
Raner GM; Hatchell AJ; Morton PE; Ballou DP; Coon MJ
Stopped-flow spectrophotometric analysis of intermediates in the peroxo-dependent inactivation of cytochrome P450 by aldehydes | 3 | 0
|
| 12142 | 9 | 12142 2000 JOURNAL OF INORGANIC BIOCHEMISTRY 81(3):183-190
Williams PA; Cosme J; Sridhar V; Johnson EF; McRee DE
Microsomal cytochrome P4502C5: comparison to microbial P450s and unique features | 23 | 7
|
| 12143 | 10 | 12143 2000 JOURNAL OF INORGANIC BIOCHEMISTRY 81(3):191-205
Shimizu H; Park SY; Lee DS; Shoun H; Shiro Y
Crystal structures of cytochrome P450nor and its mutants (Ser286 -> Val, Thr) in the ferric resting state at cryogenic temperature: a comparative analysis with monooxygenase cytochrome P450s | 10 | 2
|
| 12144 | 9 | 12144 2000 JOURNAL OF INVESTIGATIVE DERMATOLOGY 114(2):328-333
Katiyar SK; Matsui MS; Mukhtar H
Ultraviolet-B exposure of human skin induces cytochromes P450 1A1 and 1B1 | 13 | 2
|
| 12145 | 20 | 12145 2000 JOURNAL OF LIPID RESEARCH 41(1):66-74
Fang X; Kaduce TL; VanRollins M; Weintraub NL; Spector AA
Conversion of epoxyeicosatrienoic acids (EETs) to chain- shortened epoxy fatty acids by human skin fibroblasts | 13 | 5
|
| 12146 | 88 | 12146 2000 JOURNAL OF LIPID RESEARCH 41(2):163-181
Capdevila JH; Falck JR; Harris RC
Cytochrome P450 and arachidonic acid bioactivation: molecular and functional properties of the arachidonate monooxygenase | 51 | 16
|
| 12147 | 8 | 12147 2000 JOURNAL OF MEDICINAL CHEMISTRY 43(23):4437-4445
Hartmann RW; Hector M; Wachall BG; Palusczak A; Palzer M; Huch V; Veith M
Synthesis and evaluation of 17-aliphatic heterocycle- substituted steroidal inhibitors of 17 alpha-hydroxylase/C17- 20-lyase (P450 17) | 10 | 2
|
| 12148 | 10 | 12148 2000 JOURNAL OF NEUROSCIENCE RESEARCH 60(1):106-115
Hagemeyer CE; Rosenbrock H; Singec I; Knoth R; Volk B
Different testosterone metabolism by immortalized embryonic and postnatal hippocampal neurons from C57BL/6 mice: A crucial role for androstenedione | 2 | 2
|
| 12149 | 6 | 12149 2000 JOURNAL OF NUTRITION 130(9):2367-2370
Stupans I; Stretch G; Hayball P
Olive oil phenols inhibit human hepatic microsomal activity | 11 | 0
|
| 12150 | 3 | 12150 2000 JOURNAL OF ORGANIC CHEMISTRY 65(14):4460-4463
Rosen GM; Tsai P; Barth ED; Dorey G; Casara P; Spedding M; Halpern HJ
A one-step synthesis of 2-(2-pyridyl)-3H-indol-3-one N-oxide: Is it an efficient spin trap for hydroxyl radical? | 8 | 0
|
| 12151 | 25 | 12151 2000 JOURNAL OF PATHOLOGY 192(4):419-426
Murray GI
The role of cytochrome P450 in tumour development and progression and its potential in therapy | 13 | 2
|
| 12152 | 3 | 12152 2000 JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM 13(5):483-488
Saraco N; Berensztein E; Dardis A; Rivarola MA; Belgorosky A
Expression of the aromatase gene in the human prepubertal testis | 1 | 0
|
| 12153 | 12 | 12153 2000 JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM 13():1271-1275
Auchus RJ; Geller DH; Lee TC; Worthy KM
The function and roles of P450c17 in androgen excess states | 2 | 0
|
| 12154 | 8 | 12154 2000 JOURNAL OF PHARMACEUTICAL SCIENCES 89(8):1022-1027
Brunner LJ; Bai S
Effect of dietary oil intake on hepatic cytochrome p450 activity in the rat | 0 | 0
|
| 12155 | 23 | 12155 2000 JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS 44(1):313-324
Ekins S; Ring BJ; Grace J; McRobie-Belle DJ; Wrighton SA
Present and future in vitro approaches for drug metabolism | 22 | 1
|
| 12156 | 16 | 12156 2000 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 292(2):553-560
Moorthy B; Parker KM; Smith CV; Bend JR; Welty SE
Potentiation of oxygen-induced lung injury in rats by the mechanism-based cytochrome P-450 inhibitor, 1- aminobenzotriazole | 8 | 3
|
| 12157 | 11 | 12157 2000 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 292(3):1008-1014
Sindhu RK; Mitsuhashi M; Kikkawa Y
Induction of cytochrome P-450 1A2 by oxidized tryptophan in Hepa lclc7 cells | 3 | 0
|
| 12158 | 4 | 12158 2000 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 293(2):494-500
Abraham NG; Jiang SL; Yang LM; Zand BA; Laniado-Schwartzman M; Marji J; Drummond GS; Kappas A
Adenoviral vector-mediated transfer of human heme oxygenase in rats decreases renal heme-dependent arachidonic acid epoxygenase activity | 11 | 0
|
| 12159 | 11 | 12159 2000 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 293(2):677-685
Cummings BS; Lasker JM; Lash LH
Expression of glutathione-dependent enzymes and cytochrome P450s in freshly isolated and primary cultures of proximal tubular cells from human kidney | 9 | 1
|
| 12160 | 12 | 12160 2000 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 294(1):313-322
Moorthy B
Persistent expression of 3-methylcholanthrene-inducible cytochromes P4501A in rat hepatic and extrahepatic tissues | 6 | 1
|
| 12161 | 13 | 12161 2000 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 294(1):387-395
Yao DG; Ding SH; Burchell B; Wolf CR; Friedberg T
Detoxication of vinca alkaloids by human P450CYP3A4-mediated metabolism: Implications for the development of drug resistance | 7 | 3
|
| 12162 | 12 | 12162 2000 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 294(3):1120-1130
Thompson CM; Capdevila JH; Strobel HW
Recombinant cytochrome P450 2D18 metabolism of dopamine and arachidonic acid | 8 | 3
|
| 12163 | 13 | 12163 2000 JOURNAL OF PLANT RESEARCH 113(1112):475-488
Aoki T; Akashi T; Ayabe S
Flavonoids of leguminous plants: Structure, biological activity, and biosynthesis | 4 | 0
|
| 12164 | 19 | 12164 2000 JOURNAL OF PROTEIN CHEMISTRY 19(1):23-32
Omata Y; Dai RK; Smith SV; Robinson RC; Friedman FK
Synthetic peptide mimics of a predicted topographical interaction surface: The cytochrome P4502B1 recognition domain for NADPH-cytochrome P450 reductase | 1 | 0
|
| 12165 | 6 | 12165 2000 JOURNAL OF PSYCHIATRY & NEUROSCIENCE 25(5):481-496
Baker GB; Coutts RT; Greenshaw AJ
Neurochemical and metabolic aspects of antidepressants: an overview | 2 | 0
|
| 12166 | 7 | 12166 2000 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 75(1):57-63
Ehmer PB; Jose J; Hartmann RW
Development of a simple and rapid assay for the evaluation of inhibitors of human 17 alpha-hydroxylase-C-17,C-21-lyase (P450c17) by coexpression of P450c17 with NADPH-cytochrome- P450-reductase in Escherichia coli | 6 | 2
|
| 12167 | 6 | 12167 2000 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 122(6):1047-1056
Wirtz M; Klucik J; Rivera M
Ferredoxin-mediated electrocatalytic dehalogenation of haloalkanes by cytochrome P450(cam) | 6 | 1
|
| 12168 | 3 | 12168 2000 JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (3):253-273
Durand S; Parrain JL; Santelli M
Construction of (Z,Z) skipped 1,4-dienes. Application to the synthesis of polyunsaturated fatty acids and derivatives | 8 | 0
|
| 12169 | 4 | 12169 2000 JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2 5():983-988
Tsai P; Porasuphatana S; Pou S; Rosen GM
Investigations into the spin trapping of nitric oxide and superoxide: models to explore free radical generation by nitric oxide synthase | 0 | 0
|
| 12170 | 3 | 12170 2000 LANCET 355(9208):945-946
Park BK
Cytochrome P450 enzymes in the heart | 2 | 0
|
| 12171 | 5 | 12171 2000 LANGMUIR 16(7):3414-3421
Kloss AA; Lavrik N; Yeung C; Leckband D
Effect of the microenvironment on the recognition of immobilized cytochromes by soluble redox proteins | 5 | 0
|
| 12172 | 9 | 12172 2000 LIFE SCIENCES 66(20):1955-1967
Fujita K; Mogami A; Hayashi A; Kamataki T
Establishment of Salmonella strain expressing catalytically active human UDP-glucuronosyltransferase 1A1 (UGT1A1) | 0 | 0
|
| 12173 | 8 | 12173 2000 LIFE SCIENCES 66(22):2193-2212
Fontaine F; de Sousa G; Burcham PC; Duchene P; Rahmani R
Role of cytochrome P450 3A in the metabolism of mefloquine in human and animal hepatocytes | 2 | 1
|
| 12174 | 13 | 12174 2000 LIFE SCIENCES 67(11):1307-1316
Boucher P; Seree E; Vidon C; de Souza AC; Villard PH; Chambon R; Barra Y; Vallon JJ
Dietary lipids affect human ethanol-inducible CYP2E1 gene expression in vivo in mononuclear cells | 4 | 2
|
| 12175 | 1 | 12175 2000 LIPIDS 35(3):325-331
Williams JR
The effects of dehydroepiandrosterone on carcinogenesis, obesity, the immune system, and aging | 12 | 1
|
| 12176 | 6 | 12176 2000 MAMMALIAN GENOME 11(11):1016-1023
Glusman G; Bahar A; Sharon D; Pilpel Y; White J; Lancet D
The olfactory receptor gene superfamily: data mining, classification, and nomenclature | 23 | 1
|
| 12177 | 13 | 12177 2000 MARINE BIOTECHNOLOGY 2(2):167-172
Aoki J; Sato M; Itakura T
An eel cytochrome P450 1A gene having no XRE sequences in its 5 ' upstream region of 1600 bp | 1 | 0
|
| 12178 | 5 | 12178 2000 MARINE ENVIRONMENTAL RESEARCH 50(1-5):7-10
Godard CAJ; Leaver MJ; Said MR; Dickerson RL; George S; Stegeman JJ
Identification of cytochrome P4501B-like sequences in two teleost fish species (scup, Stenotomus chrysops and plaice, Pleuronectes platessa) and in a cetacean (striped dolphin, Stenella coeruleoalba) | 5 | 2
|
| 12179 | 15 | 12179 2000 MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS 12(1-2):103-109
Hara M
Application of P450s for biosensing: combination of biotechnology and electrochemistry | 3 | 2
|
| 12180 | 7 | 12180 2000 MEDICINA CLINICA 114(4):121-127
Fernandez J; Montemayor T; Bautista J; Marquez R; Jimenez L; Arenas J; Campos Y; Castillo J
Role of cardiopulmonary exercise test in patients with mitochondrial myopathies | 2 | 0
|
| 12181 | 11 | 12181 2000 METAL-OXO AND METAL-PEROXO SPECIES IN CATALYTIC OXIDATIONS 97():1-35
Meunier B; Bernadou J
Active iron-oxo and iron-peroxo species in cytochromes p450 and peroxidases; Oxo-hydroxo tautomerism with water-soluble metalloporphyrins | 19 | 2
|
| 12182 | 7 | 12182 2000 METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY 22(9):695-705
Isaza CA; Henao J; Lopez AM; Cacabelos R
Isolation, sequence and genotyping of the drug metabolizer CYP2D6 gene in the Colombian population | 1 | 0
|
| 12183 | 14 | 12183 2000 MOLECULAR AND CELLULAR ENDOCRINOLOGY 164(1-2):169-181
Ijiri S; Berard C; Trant JM
Characterization of gonadal and extra-gonadal forms of the cDNA encoding the Atlantic stingray (Dasyatis sabina) cytochrome P450 aromatase (CYP19) | 5 | 0
|
| 12184 | 1 | 12184 2000 MOLECULAR BIOLOGY 34(3):351-355
Schwartz EI; Duzhak TG; Gulyaeva LF; Lyakhovich VV
Effect of inducers on the interaction of the positive and negative cis-acting elements of the CYP2B2 gene with rat liver nuclear proteins | 0 | 0
|
| 12185 | 65 | 12185 2000 MOLECULAR BIOTECHNOLOGY 16(3):233-251
Imig JD
Epoxygenase metabolites - Epithelial and vascular actions | 3 | 0
|
| 12186 | 2 | 12186 2000 MOLECULAR BRAIN RESEARCH 78(1-2):38-49
Oyan AM; Nilsen F; Goksoyr A; Holmqvist B
Partial cloning of constitutive and inducible nitric oxide synthases and detailed neuronal expression of NOS mRNA in the cerebellum and optic tectum of adult Atlantic salmon (Salmo salar) | 7 | 0
|
| 12187 | 6 | 12187 2000 MOLECULAR ENDOCRINOLOGY 14(6):875-888
Compagnone NA; Zhang P; Vigne JL; Mellon SH
Novel role for the nuclear phosphoprotein SET in transcriptional activation of P450c17 and initiation of neurosteroidogenesis | 8 | 1
|
| 12188 | 15 | 12188 2000 MOLECULAR PHARMACOLOGY 58(1):48-57
Huss JM; Kasper CB
Two-stage glucocorticoid induction of CYP3A23 through both the glucocorticoid and pregnane X receptors | 13 | 7
|
| 12189 | 18 | 12189 2000 MOLECULAR PHARMACOLOGY 58(2):279-287
Tsao CC; Foley J; Coulter SJ; Maronpot R; Zeldin DC; Goldstein JA
CYP2C40, a unique arachidonic acid 16-hydroxylase, is the major CYP2C in murine intestinal tract | 4 | 2
|
| 12190 | 5 | 12190 2000 MOLECULAR PHARMACOLOGY 58(5):976-981
Hodgkinson CP; Wright MC; Paine AJ
Fibronectin-mediated hepatocyte shape change reprograms cytochrome p450 2C11 gene expression via an integrin-signaled induction of ribonuclease activity | 4 | 1
|
| 12191 | 4 | 12191 2000 MUTAGENESIS 15(1):9-15
Jensen KG; Wiberg K; Klasson-Wehler E; Onfelt A
Induction of aberrant mitosis with PCBs: particular efficiency of 2,3,3 ',4,4 '-pentachlorobiphenyl and synergism with triphenyltin | 0 | 0
|
| 12192 | 9 | 12192 2000 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 454(1-2):45-52
Cooper MT; Porter TD
Mutagenicity of nitrosamines in methyltransferase-deficient strains of Salmonella typhimurium coexpressing human cytochrome P450 2E1 and reductase | 6 | 5
|
| 12193 | 16 | 12193 2000 MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS 471(1-2):135-143
Kushida H; Fujita K; Suzuki A; Yamada M; Nohmi T; Kamataki T
Development of a Salmonella tester strain sensitive to promutagenic N-nitrosamines: expression of recombinant CYP2A6 and human NADPH-cytochrome P450 reductase in S-typhimurium YG7108 | 10 | 5
|
| 12194 | 15 | 12194 2000 MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS 472(1-2):129-138
Yamazaki H; Hatanaka N; Kizu R; Hayakawa K; Shimada N; Guengerich FP; Nakajima M; Yokoi T
Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1- nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1 | 9 | 4
|
| 12195 | 8 | 12195 2000 NEUROCHEMISTRY INTERNATIONAL 36(4-5):451-459
McKenna MC; Stevenson JH; Huang XL; Tildon JT; Zielke CL; Hopkins IB
Mitochondrial malic enzyme activity is much higher in mitochondria from cortical synaptic terminals compared with mitochondria from primary cultures of cortical neurons or cerebellar granule cells | 15 | 0
|
| 12196 | 9 | 12196 2000 NEUROIMMUNOMODULATION 917():121-134
Kozak W; Kluger MJ; Tesfaigzi J; Kozak A; Mayfield KP; Wachulec M; Dokladny K
Molecular mechanisms of fever and endogenous antipyresis | 7 | 2
|
| 12197 | 5 | 12197 2000 NEUROIMMUNOMODULATION 917():971-982
Morfin R; Lafaye P; Cotillon AC; Nato F; Chmielewski V; Pompon D
7 alpha-hydroxy-dehydroepiandrosterone and immune response | 4 | 1
|
| 12198 | 4 | 12198 2000 NEUROLOGIC CLINICS 18(1):15-+
Taivassalo T; Reddy H; Matthews PM
Muscle responses to exercise in health and disease | 1 | 0
|
| 12199 | 4 | 12199 2000 NEUROLOGY 55(5):644-649
Karadimas CL; Greenstein P; Sue CM; Joseph JT; Tanji K; Haller RG; Taivassalo T; Davidson MM; Shanske S; Bonilla E; DiMauro S
Recurrent myoglobinuria due to a nonsense mutation in the COX I gene of mitochondrial DNA | 25 | 3
|
| 12200 | 8 | 12200 2000 NEW MEDICATIONS FOR DRUG ABUSE 909():233-246
Sellers EM; Tyndale RF
Mimicking gene defects to treat drug dependence | 7 | 0
|
| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 12201 | 7 | 12201 2000 NUCLEIC ACIDS RESEARCH 28(5):1126-1132
Kim J; Rivera-Rivera I; Kemper B
Tissue-specific chromatin structure of the phenobarbital- responsive unit and proximal promoter of CYP2B1/2 and modulation by phenobarbital | 4 | 0
|
| 12202 | 4 | 12202 2000 ONCOGENE 19(21):2585-2597
Herrington J; Smit LS; Schwartz J; Carter-Su C
The role of STAT proteins in growth hormone signaling | 29 | 0
|
| 12203 | 7 | 12203 2000 OTOLARYNGOLOGY-HEAD AND NECK SURGERY 123(1):1-8
Sherman BE; Chole RA
Effects of leukotriene and cyclo-oxygenase inhibition on adaptive bone remodeling in the middle ear | 0 | 0
|
| 12204 | 8 | 12204 2000 PARASITOLOGY 120():399-407
Lockyer AE; Jones CS; Noble LR; Rollinson D
Use of differential display to detect changes in gene expression in the intermediate snail host Biomphalaria glabrata upon infection with Schistosoma mansoni | 9 | 0
|
| 12205 | 2 | 12205 2000 PATHOLOGY INTERNATIONAL 50(5):353-362
Kitano M
Host genes controlling the susceptibility and resistance to squamous cell carcinoma of the tongue in a rat model | 0 | 0
|
| 12206 | 23 | 12206 2000 PEDIATRIC RESEARCH 47(5):677-683
Treluyer JM; Benech H; Colin I; Pruvost A; Cheron G; Cresteil T
Ontogenesis of CYP2C-dependent arachidonic acid metabolism in the human liver: Relationship with sudden infant death syndrome | 7 | 1
|
| 12207 | 10 | 12207 2000 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 68(1):11-25
Yamada T; Kambara Y; Imaishi H; Ohkawa H
Molecular cloning of novel cytochrome P450 species induced by chemical treatments in cultured tobacco cells | 4 | 0
|
| 12208 | 8 | 12208 2000 PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 439(3):R56-R57
Rozman D
Lanosterol 14 alpha-demethylase (CYP51) - a cholesterol biosynthetic enzyme involved in production of meiosis activating sterols in oocytes and testis - a minireview | 6 | 2
|
| 12209 | 16 | 12209 2000 PHARMACOGENETICS 10(5):373-388
Ozdemir V; Kalow W; Tang BK; Paterson AD; Walker SE; Endrenyi L; Kashuba ADM
Evaluation of the genetic component of variability in CYP3A4 activity: a repeated drug administration method | 27 | 7
|
| 12210 | 14 | 12210 2000 PHARMACOGENETICS 10(8):667-678
Sheng JJ; Guo JC; Hua ZC; Caggana M; Ding XX
Characterization of human CYP2G genes: widespread loss-of- function mutations and genetic polymorphism | 6 | 4
|
| 12211 | 20 | 12211 2000 PHARMACOLOGY 61(3):124-135
Nebert DW; Dieter MZ
The evolution of drug metabolism | 9 | 3
|
| 12212 | 15 | 12212 2000 PHARMACOLOGY 61(3):147-153
Kimura S; Gonzalez F
Applications of genetically manipulated mice in pharmacogenetics and pharmacogenomics | 5 | 0
|
| 12213 | 16 | 12213 2000 PHARMACOLOGY & THERAPEUTICS 85(1):11-28
Hiemke C; Hartter S
Pharmacokinetics of selective serotonin reuptake inhibitors | 47 | 1
|
| 12214 | 41 | 12214 2000 PHARMACOLOGY & THERAPEUTICS 86(1):1-28
Nakagawa K; Ishizaki T
Therapeutic relevance of pharmacogenetic factors in cardiovascular medicine | 9 | 0
|
| 12215 | 9 | 12215 2000 PHARMACOLOGY & TOXICOLOGY 86(5):215-221
Taavitsainen P; Anttila M; Nyman L; Karnani H; Salonen JS; Pelkonen O
Selegiline metabolism and cytochrome P450 enzymes: In vitro study in human liver microsomes | 10 | 1
|
| 12216 | 5 | 12216 2000 PHARMACOLOGY & TOXICOLOGY 87(4):174-178
Skaanild MT; Friis C
Expression changes of CYP2A and CYP3A in microsomes from pig liver and cultured hepatocytes | 2 | 0
|
| 12217 | 6 | 12217 2000 PHARMACOTHERAPY 20(8):139S-151S
Cloyd JC; Remmel RP
Antiepileptic drug pharmacokinetics and interactions: Impact on treatment of epilepsy | 8 | 0
|
| 12218 | 3 | 12218 2000 PHARMACOTHERAPY 20(3):280-291
Higa GM
Altering the estrogenic milieu of breast cancer with a focus on the new aromatase inhibitors | 1 | 0
|
| 12219 | 5 | 12219 2000 PHYTOCHEMISTRY 53(1):7-12
Yamamoto H; Katano N; Ooi A; Inoue K
Secologanin synthase which catalyzes the oxidative cleavage of loganin into secologanin is a cytochrome P450 | 11 | 1
|
| 12220 | 3 | 12220 2000 PHYTOCHEMISTRY 53(3):319-323
Utsunomiya Y; Nakayama T; Oohira H; Hirota R; Mori T; Kawai F; Ueda T
Purification and inactivation by substrate of an allene oxide synthase (CYP74) from corn (Zea mays L.) seeds | 5 | 0
|
| 12221 | 4 | 12221 2000 PHYTOTHERAPY RESEARCH 14(1):43-44
Hagymasi K; Blazovics A; Feher J; Lugasi A; Kristo ST; Kery A
The in vitro effect of dandelions antioxidants on microsomal lipid peroxidation | 2 | 0
|
| 12222 | 18 | 12222 2000 PLANT MOLECULAR BIOLOGY 44(2):141-153
Tranbarger TJ; Forward BS; Misra S
Regulation of NADPH-cytochrome P450 reductase expressed during Douglas-fir germination and seedling development | 0 | 0
|
| 12223 | 18 | 12223 2000 PLANT PHYSIOLOGY 122(4):1311-1321
Nielsen JS; Moller BL
Cloning and expression of cytochrome P450 enzymes catalyzing the conversion of tyrosine to p-hydroxyphenylacetaldoxime in the biosynthesis of cyanogenic glucosides in Triglochin maritima | 9 | 0
|
| 12224 | 1 | 12224 2000 PLASMID 43(1):35-48
Stockwell D; Lelianova V; Thompson T; Dempsey WB
Transcription of the transfer genes traY and traM of the antibiotic resistance plasmid R100-1 is linked | 0 | 0
|
| 12225 | 5 | 12225 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(1):331-336
Tiffert T; Ginsburg H; Krugliak M; Elford BC; Lew VL
Potent antimalarial activity of clotrimazole in in vitro cultures of Plasmodium falciparum | 9 | 0
|
| 12226 | 2 | 12226 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(5):2379-2384
Hull AK; Vij R; Celenza JL
Arabidopsis cytochrome P450s that catalyze the first step of tryptophan-dependent indole-3-acetic acid biosynthesis | 52 | 2
|
| 12227 | 2 | 12227 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(10):5203-5207
Patterson GH; Knobel SM; Arkhammar P; Thastrup O; Piston DW
Separation of the glucose-stimulated cytoplasmic mitochondrial NAD(P)H responses in pancreatic islet beta cells | 14 | 0
|
| 12228 | 9 | 12228 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(20):10769-10774
Handschin C; Podvinec M; Meyer UA
CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR) | 22 | 6
|
| 12229 | 3 | 12229 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(20):11080-11085
Gnaiger E; Mendez G; Hand SC
High phosphorylation efficiency and depression of uncoupled respiration in mitochondria under hypoxia | 23 | 0
|
| 12230 | 18 | 12230 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(22):11948-11953
Schalk M; Croteau R
A single amino acid substitution (F363I) converts the regiochemistry of the spearmint (-)-limonene hydroxylase from a C6-to a C3-hydroxylase | 10 | 2
|
| 12231 | 64 | 12231 2000 PROSTAGLANDINS & OTHER LIPID MEDIATORS 62(3):271-292
Capdevila JH; Falck JR
Biochemical and molecular characteristics of the cytochrome P450 arachidonic acid monooxygenase | 5 | 2
|
| 12232 | 4 | 12232 2000 PROSTATE 45(4):304-314
Pinto JT; Qiao CH; Xing J; Suffoletto BP; Schubert KB; Rivlin RS; Huryk RF; Bacich DJ; Heston WDW
Alterations of prostate biomarker expression and testosterone utilization in human LNCaP prostatic carcinoma cells by garlic- derived S-allylmercaptocysteine | 7 | 0
|
| 12233 | 9 | 12233 2000 PROTEIN EXPRESSION AND PURIFICATION 18(3):310-315
Hull AK; Celenza JL
Bacterial expression and purification of the Arabidopsis NADPH- cytochrome P450 reductase ATR2 | 0 | 0
|
| 12234 | 10 | 12234 2000 PROTEIN EXPRESSION AND PURIFICATION 19(1):173-178
Mulrooney SB; Waskell L
High-level expression in Escherichia coli and purification of the membrane-bound form of cytochrome b(5) | 4 | 0
|
| 12235 | 29 | 12235 2000 PROTEINS-STRUCTURE FUNCTION AND GENETICS 40(4):590-612
Grinberg AV; Hannemann F; Schiffler B; Muller J; Heinemann U; Bernhardt R
Adrenodoxin: Structure, stability, and electron transfer properties | 33 | 7
|
| 12236 | 13 | 12236 2000 PURE AND APPLIED CHEMISTRY 72(6):985-994
Arinc E; Sen A; Bozcaarmutlu A
Cytochrome P4501A and associated mixed-function oxidase induction in fish as a biomarker for toxic carcinogenic pollutants in the aquatic environment | 4 | 4
|
| 12237 | 2 | 12237 2000 RAPID COMMUNICATIONS IN MASS SPECTROMETRY 14(17):1619-1624
Bu HZ; Magis L; Knuth K; Teitelbaum P
High-throughput cytochrome P450 (CYP) inhibition screening via cassette probe-dosing strategy. I. Development of direct injection/on-line guard cartridge extraction/tandem mass spectrometry for the simultaneous detection of CYP probe substrates and their metabolites | 13 | 1
|
| 12238 | 3 | 12238 2000 REVISTA DE NEUROLOGIA 30():S94-S104
Adin J; Gutierrez-Rubio F; Armijo JA
Antiepileptic drugs and the liver | 1 | 0
|
| 12239 | 8 | 12239 2000 SCIENCE 287(5458):1615-1622
Schlichting I; Berendzen J; Chu K; Stock AM; Maves SA; Benson DE; Sweet BM; Ringe D; Petsko GA; Sligar SG
The catalytic pathway of cytochrome P450cam at atomic resolution | 193 | 15
|
| 12240 | 3 | 12240 2000 SCIENCE OF THE TOTAL ENVIRONMENT 247(2-3):295-311
Cajaraville MP; Bebianno MJ; Blasco J; Porte C; Sarasquete C; Viarengo A
The use of biomarkers to assess the impact of pollution in coastal environments of the Iberian Peninsula: a practical approach | 17 | 0
|
| 12241 | 37 | 12241 2000 SCIENCE OF THE TOTAL ENVIRONMENT 247(2-3):313-332
Sarasquete C; Segner H
Cytochrome P4501A (CYP1A) in teleostean fishes. A review of immunohistochemical studies | 7 | 3
|
| 12242 | 34 | 12242 2000 SEIBUTSU-KOGAKU KAISHI 78(3):82-93
Kagawa N; Kusano K; Nonaka Y
Heterologous expression of mammalian cytochrome P450 as active forms in Escherichia coli - Review | 2 | 0
|
| 12243 | 5 | 12243 2000 SHOCK 13(4):279-284
Lee SM; Park MJ; Cho TS; Clemens MG
Hepatic injury and lipid peroxidation during ischemia and reperfusion | 8 | 2
|
| 12244 | 7 | 12244 2000 STEROIDS 65(4):171-179
Brodie AMH; Njar VCO
Aromatase inhibitors and their application in breast cancer treatment | 25 | 0
|
| 12245 | 10 | 12245 2000 THORAX 55():S13-S16
Carroll MA; McGiff JC
A new class of lipid mediators: cytochrome P450 arachidonate metabolites | 5 | 2
|
| 12246 | 7 | 12246 2000 TOXICOLOGICAL SCIENCES 54(1):183-193
Ziccardi MH; Gardner IA; Denison MS
Development and modification of a recombinant cell bioassay to directly detect halogenated and polycyclic aromatic hydrocarbons in serum | 15 | 1
|
| 12247 | 7 | 12247 2000 TOXICOLOGICAL SCIENCES 55(2):266-273
Jackson TE; Lilly PD; Recio L; Schlosser PM; Medinsky MA
Inhibition of cytochrome P450 2E1 decreases, but does not eliminate, genotoxicity mediated by 1,3-butadiene | 5 | 2
|
| 12248 | 17 | 12248 2000 TOXICOLOGICAL SCIENCES 55(2):352-360
Krovat BC; Tracy JH; Omiecinski CJ
Fingerprinting of cytochrome P450 and microsomal epoxide hydrolase gene expression in human blood cells | 10 | 0
|
| 12249 | 3 | 12249 2000 TOXICOLOGICAL SCIENCES 58(1):3-4
Snyder R
Cytochrome p450, the oxygen-activating enzyme in xenobiotic metabolism | 0 | 0
|
| 12250 | 14 | 12250 2000 TOXICOLOGY 144(1-3):31-38
Doostdar H; Burke MD; Mayer RT
Bioflavonoids: selective substrates and inhibitors for cytochrome P450CYP1A and CYP1B1 | 24 | 2
|
| 12251 | 8 | 12251 2000 TOXICOLOGY 144(1-3):211-219
Jansson I; Stoilov I; Sarfarazi M; Schenkman JB
Enhanced expression of CYP1B1 in Escherichia coli | 7 | 4
|
| 12252 | 16 | 12252 2000 TOXICOLOGY 153(1-3):221-253
Lerche-Langrand C; Toutain HJ
Precision-cut liver slices: characteristics and use for in vitro pharmaco-toxicology | 13 | 0
|
| 12253 | 19 | 12253 2000 TOXICOLOGY AND APPLIED PHARMACOLOGY 164(1):24-37
Gannon M; Gilday D; Rifkind AB
TCDD induces CYP1A4 and CYP1A5 in chick liver and kidney and only CYP1A4, an enzyme lacking arachidonic acid epoxygenase activity, in myocardium and vascular endothelium | 6 | 1
|
| 12254 | 6 | 12254 2000 TOXICOLOGY AND APPLIED PHARMACOLOGY 164(1):46-54
Lee KM; Muralidhara S; Schnellmann RG; Bruckner JV
Contribution of direct solvent injury to the dose-dependent kinetics of trichloroethylene: Portal vein administration to rats | 2 | 0
|
| 12255 | 16 | 12255 2000 TOXICOLOGY AND APPLIED PHARMACOLOGY 164(3):305-311
Serron SC; Dwivedi N; Backes WL
Ethylbenzene induces microsomal oxygen free radical generation: Antibody-directed characterization of the responsible cytochrome P450 enzymes | 8 | 1
|
| 12256 | 15 | 12256 2000 TOXICOLOGY AND APPLIED PHARMACOLOGY 165(2):158-162
Gu J; Su T; Chen Y; Zhang QY; Ding XX
Expression of biotransformation enzymes in human fetal olfactory mucosa: Potential roles in developmental toxicity | 8 | 5
|
| 12257 | 5 | 12257 2000 TOXICOLOGY AND APPLIED PHARMACOLOGY 166(1):43-50
Fan L; Ovadia M; Friedman DM; Rifkind AB
Ventricular preexcitation sensitive to flecainide in late stage chick embryo ECGs: 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs inotropic but not chronotropic or dromotropic responses to isoproterenol and confers resistance to flecainide | 1 | 0
|
| 12258 | 28 | 12258 2000 TOXICOLOGY AND APPLIED PHARMACOLOGY 167(3):237-245
Giorgi M; Marini S; Longo V; Mazzaccaro A; Amato G; Gervasi PG
Cytochrome P450-dependent monooxygenase activities and their inducibility by classic P450 inducers in the liver, kidney, and nasal mucosa of male adult ring-necked pheasants | 1 | 0
|
| 12259 | 7 | 12259 2000 TRENDS IN PHARMACOLOGICAL SCIENCES 21(4):121-124
Quilley J; McGiff JC
Is EDHF an epoxyeicosatrienoic acid? | 32 | 3
|
| 12260 | 4 | 12260 2000 TRENDS IN PHARMACOLOGICAL SCIENCES 21(4):127-128
Zeldin DC; Liao JK
Reply: cytochrome P450-derived eicosanoids and the vascular wall | 4 | 1
|
| 12261 | 5 | 12261 2000 VETERINARNI MEDICINA 45(10-11):322-326
Sivikova K; Dianovsky J
A decrease of sister chromatid exchanges induced by carbon tetrachloride in cultured sheep peripheral lymphocytes by vitamin E and selenium | 0 | 0
|
| 12262 | 1 | 12262 2000 VETERINARY CLINICS OF NORTH AMERICA-FOOD ANIMAL PRACTICE 16(3):531-+
Panter KE; Stegelmeier BL
Reproductive toxicoses of food animals | 0 | 0
|
| 12263 | 25 | 12263 2000 VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 58 58():53-87
Szklarz GD; Graham SE; Paulsen MD
Molecular modeling of mammalian cytochromes P450: Application to study enzyme function | 8 | 1
|
| 12264 | 5 | 12264 2000 VOPROSY MEDITSINSKOI KHIMII 46(2):117-126
Grishanova AY; Zueva TV
Bilirubin as the endogenous intermediary in activation of CYP1A1 expression under ultrasound action | 0 | 0
|
| 12265 | 7 | 12265 2000 WORLD JOURNAL OF SURGERY 24(1):49-53
Izuishi K; Wakabayashi H; Maeba T; Ryu M; Maeta H
Lidocaine-metabolizing activity after warm ischemia and reperfusion of the rat liver in vivo | 0 | 0
|
| 12266 | 26 | 12266 2000 XENOBIOTICA 30(1):1-25
Lewis DFV; Bird MG; Dickins M; Lake BG; Eddershaw PJ; Tarbit MH; Goldfarb PS
Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the putative active site of the human CYP2E1 isoform | 15 | 4
|
| 12267 | 7 | 12267 2000 XENOBIOTICA 30(1):61-70
Yamazaki H; Suzuki M; Tane K; Shimada N; Nakajima M; Yokoi T
In vitro inhibitory effects of troglitazone and its metabolites on drug oxidation activities of human cytochrome P450 enzymes: comparison with pioglitazone and rosiglitazone | 25 | 3
|
| 12268 | 11 | 12268 2000 XENOBIOTICA 30(2):141-154
Yin H; Racha J; Li SY; Olejnik N; Satoh H; Moore D
Automated high throughput human CYP isoform activity assay using SPE-LC/MS method: application in CYP inhibition evaluation | 23 | 3
|
| 12269 | 15 | 12269 2000 XENOBIOTICA 30(3):285-295
Inoue K; Asao T; Shimada T
Ethnic-related differences in the frequency distribution of genetic polymorphisms in the CYP1A1 and CYP1B1 genes in Japanese and Caucasian populations | 15 | 2
|
| 12270 | 3 | 12270 2000 XENOBIOTICA 30(3):297-306
Bach MV; Coutts RT; Baker GB
Metabolism of N,N-dialkylated amphetamines, including deprenyl, by CYP2D6 expressed in a human cell line | 7 | 1
|
| 12271 | 6 | 12271 2000 XENOBIOTICA 30(4):371-380
Tuvesson H; Strandgarden K; Nordle O; Gunnarsson PO; Seidegard J; Persson R
Metabolism of roquinimex in mouse and rat: an in vitro/in vivo comparison | 1 | 1
|
| 12272 | 18 | 12272 2000 XENOBIOTICA 30(6):547-564
Miksys S; Rao Y; Sellers EM; Kwan M; Mendis D; Tyndale RF
Regional and cellular distribution of CYP2D subfamily members in rat brain | 6 | 1
|
| 12273 | 12 | 12273 2000 XENOBIOTICA 30(6):589-607
Meunier V; Bourrie M; Julian B; Marti E; Guillou F; Berger Y; Fabre G
Expression and induction of CYP1A1/1A2, CYP2A6 and CYP3A4 in primary cultures of human hepatocytes: a 10-year follow-up | 12 | 1
|
| 12274 | 12 | 12274 2000 XENOBIOTICA 30(7):665-681
Hewitt NJ; Fischer T; Zuehlke U; Oesch F; Utesch D
Metabolic activity of fresh and cryopreserved cynomolgus monkey (Macaca fascicularis) hepatocytes | 2 | 0
|
| 12275 | 14 | 12275 2000 XENOBIOTICA 30(8):745-754
Mankowski DC; Lawton MP; Ekins S
Characterization of transgenic mouse strains using six human hepatic cytochrome P450 probe substrates | 2 | 2
|
| 12276 | 13 | 12276 2000 XENOBIOTICA 30(8):781-795
Price RJ; Surry D; Renwick AB; Meneses-Lorente G; Lake BG; Evans DC
CYP isoform induction screening in 96-well plates: use of 7- benzyloxy-4-trifluoromethylcoumarin as a substrate for studies with rat hepatocytes | 4 | 1
|
| 12277 | 8 | 12277 2000 XENOBIOTICA 30(9):905-914
Tuvesson H; Wienkers LC; Gunnarsson PO; Seidegard J; Persson R
Identification of cytochrome P4503A as the major subfamily responsible for the metabolism of roquinimex in man | 1 | 1
|
| 12278 | 17 | 12278 2000 XENOBIOTICA 30(10):955-969
Renwick AB; Surry D; Price RJ; Lake BG; Evans DC
Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms | 5 | 4
|
| 12279 | 10 | 12279 2000 XENOBIOTICA 30(10):971-982
Emoto C; Yamazaki H; Yamasaki S; Shimada N; Nakajima M; Yokoi T
Use of everted sacs of mouse small intestine as enzyme sources for the study of drug oxidation activities in vitro | 3 | 1
|
| 12280 | 5 | 12280 2000 XENOBIOTICA 30(12):1123-1130
Lee HS; Lee HY; Gu HK; Han SS; Yun CH; Kim JH; Kim JA; Lee ES; Nam DH; Jeong TC
Effects of flupyrazofos on liver microsomal cytochrome P450 in the male Fischer 344 rat | 0 | 0
|
| 12281 | 28 | 12281 2000 XENOBIOTICA 30(12):1131-1152
Bogaards JJP; Bertrand M; Jackson P; Oudshoorn MJ; Weaver RJ; van Bladeren PJ; Walther B
Determining the best animal model for human cytochrome P450 activities: a comparison of mouse, rat, rabbit, dog, micropig, monkey and man | 5 | 2
|
| 12282 | 31 | 12282 2000 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN 120(12):1347-1357
Yamazaki H
Roles of human cytochrome P450 enzymes involved in drug metabolism and toxicological studies | 0 | 0
|
| 12283 | 19 | 12283 2000 YEAST 16(12):1077-1087
Lida T; Sumita T; Ohta A; Takagi M
The cytochrome P450ALK multigene family of an n-alkane- assimilating yeast, Yarrowia lipolytica: cloning and characterization of genes coding for new CYP52 family members | 4 | 1
|
| 12284 | 8 | 12284 2001 ACTA PHARMACOLOGICA SINICA 22(3):283-288
Shu Y; Cheng ZN; Liu ZQ; Wang LS; Zhu B; Huang SL; Ou-Yang DS; Zhou HH
Interindividual variations in levels and activities of cytochrome P-450 in liver microsomes of Chinese subjects | 2 | 1
|
| 12285 | 14 | 12285 2001 ADVANCED SYNTHESIS & CATALYSIS 343(6-7):601-606
Farinas ET; Schwaneberg U; Glieder A; Arnold FH
Directed evolution of a cytochrome P450 monooxygenase for alkane oxidation | 8 | 4
|
| 12286 | 6 | 12286 2001 ADVANCES IN INORGANIC CHEMISTRY, VOL 51 51():107-162
Veitch NC; Smith AT
Horseradish peroxidase | 25 | 0
|
| 12287 | 4 | 12287 2001 ADVANCES IN INSECT PHYSIOLOGY, VOL 28 28():1-83
Dow JAT; Davies SA
The Drosophila melanogaster malpighian tubule | 8 | 0
|
| 12288 | 4 | 12288 2001 ALTEX-ALTERNATIVEN ZU TIEREXPERIMENTEN 18(2):91-101
Nussler AK; Wang A; Neuhaus P; Fischer J; Yuan J; Liu LG; Zeilinger K; Gerlach J; Arnold PJ; Albrecht W
The suitability of hepatocyte culture models to study various aspects of drug metabolism | 2 | 0
|
| 12289 | 3 | 12289 2001 AMERICAN JOURNAL OF HYPERTENSION 14(6):62S-67S
Zhang F; Kaide JI; Rodriguez-Mulero F; Abraham NG; Nasjletti A
Vasoregulatory function of the heme-heme oxygenase-carbon monoxide system | 8 | 0
|
| 12290 | 7 | 12290 2001 AMERICAN JOURNAL OF PATHOLOGY 158(1):323-332
Ward JM; Yoon M; Anver MR; Haines DC; Kudo G; Gonzalez FJ; Kimura S
Hyalinosis and Ym1/Ym2 gene expression in the stomach and respiratory tract of 129S4/SvJae and wild-type and CYP1A2-null B6,129 mice | 8 | 0
|
| 12291 | 30 | 12291 2001 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 280(1):H1-H10
Jacobs ER; Zeldin DC
The lung HETEs (and EETs) up | 13 | 6
|
| 12292 | 3 | 12292 2001 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 280(2):H603-H609
Brass EP; Hiatt WR; Gardner AW; Hoppel CL
Decreased NADH dehydrogenase and ubiquinol-cytochrome c oxidoreductase in peripheral arterial disease | 3 | 0
|
| 12293 | 15 | 12293 2001 AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 280(5):L965-L973
Benoit C; Renaudon B; Salvail D; Rousseau E
EETs relax airway smooth muscle via an EpDHF effect: BKCa channel activation and hyperpolarization | 4 | 0
|
| 12294 | 9 | 12294 2001 AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 164(3):425-432
Flaherty KR; Wald J; Weisman IM; Zeballos RJ; Schork MA; Blaivas M; Rubenfire M; Martinez FJ
Unexplained exertional limitation - Characterization of patients with a mitochondrial myopathy | 10 | 3
|
| 12295 | 17 | 12295 2001 AMERICAN JOURNAL ON ADDICTIONS 10():29-50
Lieber CS
Liver diseases by alcohol and hepatitis C: Early detection and new insights in pathogenesis lead to improved treatment | 6 | 0
|
| 12296 | 7 | 12296 2001 AMERICAN ZOOLOGIST 41(4):877-889
Fogleman JC; Danielson PB
Chemical interactions in the cactus-microorganism-Drosophila model system of the Sonoran Desert | 0 | 0
|
| 12297 | 16 | 12297 2001 ANALYTICAL BIOCHEMISTRY 292(1):115-124
Nithipatikom K; DiCamelli RF; Kohler S; Gumina RJ; Falck JR; Campbell WB; Gross GJ
Determination of cytochrome P450 metabolites of arachidonic acid in coronary venous plasma during ischemia and reperfusion in dogs | 5 | 1
|
| 12298 | 17 | 12298 2001 ANALYTICAL BIOCHEMISTRY 295(2):248-256
Tachibana S; Tanaka M
Simultaneous determination of testosterone metabolites in liver microsomes using column-switching semi-microcolumn high- performance liquid chromatography | 2 | 1
|
| 12299 | 29 | 12299 2001 ANALYTICAL BIOCHEMISTRY 298(2):327-336
Nithipatikom K; Grall AJ; Holmes BB; Harder DR; Falck JR; Campbell WB
Liquid chromatographic-electrospray ionization-mass spectrometric analysis of cytochrome P450 metabolites of arachidonic acid | 9 | 1
|
| 12300 | 4 | 12300 2001 ANALYTICAL BIOCHEMISTRY 299(2):227-234
Watanabe T; Hammock BD
Rapid determination of soluble epoxide hydrolase inhibitors in rat hepatic microsomes by high-performance liquid chromatography with electrospray tandem mass spectrometry | 1 | 1
|
| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 12301 | 6 | 12301 2001 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 40(21):3948-3959
Powell KA; Ramer SW; del Cardayre SB; Stemmer WPC; Tobin MB; Longchamp PF; Huisman GW
Directed evolution and biocatalysis | 20 | 0
|
| 12302 | 3 | 12302 2001 ANIMAL REPRODUCTION SCIENCE 66(1-2):35-46
Rabiee AR; Macmillan KL; Schwarzenberger F
Progesterone metabolism in ovariectomised non-lactating Holstein-Friesian cows treated with progesterone with two levels of feed intake | 9 | 0
|
| 12303 | 4 | 12303 2001 ANNALS OF NEUROLOGY 50(2):133-141
Taivassalo T; Shoubridge EA; Chen J; Kennaway NG; DiMauro S; Arnold DL; Haller RG
Aerobic conditioning in patients with mitochondrial myopathies: Physiological, biochemical, and genetic effects | 11 | 4
|
| 12304 | 2 | 12304 2001 ANNALS OF PHARMACOTHERAPY 35(1):21-25
Schulz M; Schmoldt A; Donn F; Becker H
Lack of methemoglobinemia with flutamide | 0 | 0
|
| 12305 | 25 | 12305 2001 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 41():297-316
Murray GI; Melvin WT; Greenlee WF; Burke MD
Regulation, function, and tissue-specific expression of cytochrome P450CYP1B1 | 30 | 4
|
| 12306 | 23 | 12306 2001 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 41():535-567
Lin JH; Lu AYH
Interindividual variability in inhibition and induction of cytochrome P450 enzymes | 23 | 5
|
| 12307 | 33 | 12307 2001 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 41():815-850
Xie HG; Kim RB; Wood AJJ; Stein CM
Molecular basis of ethnic differences in drug disposition and response | 30 | 1
|
| 12308 | 4 | 12308 2001 ANTI-CANCER DRUGS 12(4):351-358
Malingre MM; Beijnen JH; Rosing H; Koopman FJ; van Tellingen O; Duchin K; Huinink WWT; Swart M; Lieverst J; Schellens JHM
The effect of different doses of cyclosporin A on the systemic exposure of orally administered paclitaxel | 3 | 1
|
| 12309 | 3 | 12309 2001 ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT 11(1):1-6
Brand RM; Hannah TL; Norris J; Iversen PL
Transdermal delivery of antisense oligonucleotides can induce changes in gene expression in vivo | 7 | 0
|
| 12310 | 15 | 12310 2001 APPLIED AND ENVIRONMENTAL MICROBIOLOGY 67(12):5735-5739
Li QS; Ogawa J; Schmid RD; Shimizu S
Engineering cytochrome P450BM-3 for oxidation of polycyclic aromatic hydrocarbons | 4 | 3
|
| 12311 | 3 | 12311 2001 APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 55(2):187-191
Jung Y; Kwak J; Lee Y
High-level production of heme-containing holoproteins in Escherichia coli | 1 | 1
|
| 12312 | 7 | 12312 2001 AQUATIC TOXICOLOGY 51(3):319-333
van Hezik CM; Letcher RJ; de Geus HJ; Wester PG; Goksoyr A; Lewis WE; Boon JP
Indications for the involvement of a CYP3A-like iso-enzyme in the metabolism of chlorobornane (Toxaphene (R)) congeners in seals from inhibition studies with liver microsomes | 5 | 0
|
| 12313 | 5 | 12313 2001 AQUATIC TOXICOLOGY 52(3-4):297-309
Boon JP; Lewis WE; Goksoyr A
Immunochemical and catalytic characterization of hepatic microsomal cytochrome P450 in the sperm whale (Physeter macrocephalus) | 3 | 0
|
| 12314 | 8 | 12314 2001 AQUATIC TOXICOLOGY 54(1-2):29-38
Carlsson C; Part P
7-ethoxyresorufin O-deethylase induction in rainbow trout gill epithelium cultured on permeable supports: asymmetrical distribution of substrate metabolites | 2 | 0
|
| 12315 | 10 | 12315 2001 AQUATIC TOXICOLOGY 55(3-4):177-190
Snyder MJ; Mulder EP
Environmental endocrine disruption in decapod crustacean larvae: hormone titers, cytochrome P450, and stress protein responses to heptachlor exposure | 1 | 0
|
| 12316 | 12 | 12316 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 385(1):78-87
Schenkman JB; Jansson I; Lvov Y; Rusling JF; Boussaad S; Tao NJ
Charge-dependent sidedness of cytochrome P450 forms studied by quartz crystal microbalance and atomic force microscopy | 6 | 0
|
| 12317 | 22 | 12317 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 385(2):290-300
Cvrk T; Strobel HW
Role of LYS271 and LYS279 residues in the interaction of cytochrome P4501A1 with NADPH-cytochrome P450 reductase | 4 | 2
|
| 12318 | 15 | 12318 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 385(2):311-321
Loughran PA; Roman LJ; Miller RT; Masters BSS
The kinetic and spectral characterization of the E-coli- expressed mammalian CYP4A7: Cytochrome b(5) effects vary with substrate | 11 | 10
|
| 12319 | 23 | 12319 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 387(1):117-124
Cowart LA; Falck JR; Capdevila JH
Structural determinants of active site binding affinity and metabolism by cytochrome P450BM-3 | 1 | 1
|
| 12320 | 8 | 12320 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 388(2):276-280
Woyski D; Cupp-Vickery JR
Enhanced expression of cytochrome P450s from lac-based plasmids using lactose as the inducer | 1 | 0
|
| 12321 | 30 | 12321 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 389(1):31-40
Cvrk T; Strobel HW
Role of THR501 residue in substrate binding and catalytic activity of cytochrome P4501A1 | 1 | 0
|
| 12322 | 4 | 12322 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 389(2):223-233
Marohnic CC; Barber MJ
Arginine 91 is not essential for flavin incorporation in hepatic cytochrome b(5) reductase | 6 | 5
|
| 12323 | 19 | 12323 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 389(2):264-270
He YQ; Roussel F; Halpert JR
Importance of amino acid residue 474 for substrate specificity of canine and human cytochrome p450 3A enzymes | 1 | 0
|
| 12324 | 5 | 12324 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 389(2):278-287
Fitzpatrick JL; Ripp SL; Smith NB; Pierce WM; Prough RA
Metabolism of DHEA by cytochromes P450 in rat and human liver microsomal fractions | 8 | 1
|
| 12325 | 9 | 12325 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 390(2):215-221
Gilep AA; Guryev OL; Usanov SA; Estabrook RW
Reconstitution of the enzymatic activities of cytochrome P450s using recombinant flavocytochromes containing rat cytochrome b(5) fused to NADPH-cytochrome P450 reductase with various membrane-binding segments | 2 | 2
|
| 12326 | 20 | 12326 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 390(2):222-234
Gilep AA; Guryev OL; Usanov SA; Estabrook RW
Expression, purification, and physical properties of recombinant flavocytochrome fusion proteins containing rat cytochrome b(5) linked to NADPH-cytochrome P450 reductase by different membrane-binding segments | 1 | 1
|
| 12327 | 4 | 12327 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 390(2):287-294
Zamora R; Vodovotz Y; Alarcon L; Betten B; Loughran PA; Aulak KS; Stuehr DJ; Gibson KF; Billiar TR
Nitric oxide from the inducible nitric oxide synthase (iNOS) increases the expression of cytochrome P450 2E1 in iNOS-null hepatocytes in the absence of inflammatory stimuli | 2 | 0
|
| 12328 | 14 | 12328 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 393(1):143-153
Doray B; Chen CD; Kemper B
N-terminal deletions and His-tag fusions dramatically affect expression of cytochrome P4502C2 in bacteria | 0 | 0
|
| 12329 | 15 | 12329 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 393(2):222-235
Ralston L; Kwon ST; Schoenbeck M; Ralston J; Schenk DJ; Coates RM; Chappell J
Cloning, heterologous expression, and functional characterization of 5-epi-aristolochene-1,3-dihydroxylase from tobacco (Nicotiana tabacum) | 6 | 0
|
| 12330 | 21 | 12330 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 393(2):255-261
Hanna IH; Kim MS; Guengerich FP
Heterologous expression of cytochrome P450 2D6 mutants, electron transfer, and catalysis of bufuralol hydroxylation: The role of aspartate 301 in structural integrity | 13 | 7
|
| 12331 | 26 | 12331 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 393(2):329-338
Aitken AE; Roman LJ; Loughran PA; de la Garza M; Masters BSS
Expressed CYP4A4 metabolism of prostaglandin E-1 and arachidonic acid | 2 | 1
|
| 12332 | 16 | 12332 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 394(1):45-53
Matsunaga I; Ueda A; Sumimoto T; Ichihara K; Ayata M; Ogura H
Site-directed mutagenesis of the putative distal helix of peroxygenase cytochrome P450 | 5 | 2
|
| 12333 | 9 | 12333 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 395(1):25-31
Nakamura K; Martin MV; Guengerich FP
Random mutagenesis of human cytochrome P450 2A6 and screening with indole oxidation products | 3 | 1
|
| 12334 | 13 | 12334 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 395(1):78-84
Lamb DC; Kaderbhai NN; Venkateswarlu K; Kelly DE; Kelly SL; Kaderbhai MA
Human sterol 14 alpha-demethylase activity is enhanced by the membrane-bound state of cytochrome b(5) | 1 | 1
|
| 12335 | 8 | 12335 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 395(2):158-168
Menzel R; Bogaert T; Achazi R
A systematic gene expression screen of Caenorhabditis elegans cytochrome P450 genes reveals CYP35 as strongly xenobiotic inducible | 4 | 0
|
| 12336 | 30 | 12336 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 396(1):16-24
Deeni YY; Paine MJI; Ayrton AD; Clarke SE; Chenery R; Wolf CR
Expression, purification, and biochemical characterization of a human cytochrome P450CYP2D6-NADPH cytochrome P450 reductase fusion protein | 4 | 3
|
| 12337 | 5 | 12337 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 396(1):25-34
Grinberg AV; Bernhardt R
Contribution of a salt bridge to the thermostability of adrenodoxin determined by site-directed mutagenesis | 1 | 0
|
| 12338 | 18 | 12338 2001 ARCHIVES OF TOXICOLOGY 75(6):335-345
Runge DM; Stock TW; Lehmann T; Taege C; Bernauer U; Stolz DB; Hofmann S; Foth H
Expression of cytochrome P450 2E1 in normal human bronchial epithelial cells and activation by ethanol in culture | 2 | 1
|
| 12339 | 7 | 12339 2001 ARCHIVES OF TOXICOLOGY 75(9):555-561
Suzuki T; Nakagawa Y; Tayama K; Yaguchi K; Suga T
Toxicity and effects of 2,6-di-tert-butyl-4-methylphenyl N- methylcarbamate (terbutol) on hepatic cytochrome P450 in F344 rats | 0 | 0
|
| 12340 | 4 | 12340 2001 ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH 51(4):325-331
Ezzat AR; el-Din SHS; Ebeid FA
Effect of praziquantel treatment on the activities of some liver microsomal enzymes in mice infected with Schistosoma mansoni | 0 | 0
|
| 12341 | 8 | 12341 2001 ATLA-ALTERNATIVES TO LABORATORY ANIMALS 29(2):179-192
De Smet K; Cavin C; Vercruysse A; Rogiers V
Collagen type I gel cultures of adult rat hepatocytes as a screening induction model for cytochrome P450-dependent enzymes | 1 | 0
|
| 12342 | 1 | 12342 2001 BIOCATALYSIS AND BIOTRANSFORMATION 19(1):69-83
Webster R; Beaumont K; Ritzau M; Stachulski AV
The synthesis of the glucuronide metabolite of UK-157,147 using immobilised uridine 5 '-diphosphoglucuronyl transferase and traditional organic chemistry techniques (imidate method) | 0 | 0
|
| 12343 | 13 | 12343 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 280(3):892-897
Bylund J; Bylund M; Oliw EH
cDNA cloning and expression of CYP4F12, a novel human cytochrome P450 | 12 | 6
|
| 12344 | 12 | 12344 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 280(5):1258-1261
Li QS; Ogawa J; Shimizu S
Critical role of the residue size at position 87 in H2O2- dependent substrate hydroxylation activity and H2O2 inactivation of cytochrome P450BM-3 | 6 | 4
|
| 12345 | 12 | 12345 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 281(2):529-535
Rylander T; Neve EPA; Ingelman-Sundberg M; Oscarson M
Identification and tissue distribution of the novel human cytochrome P4502S1 (CYP2S1) | 12 | 3
|
| 12346 | 14 | 12346 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 284(3):757-762
Imaoka S; Hayashi K; Hiroi T; Yabusaki Y; Kamataki T; Funae Y
A transgenic mouse expressing human CYP4B1 in the liver | 7 | 2
|
| 12347 | 7 | 12347 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 284(4):937-941
Gilep AA; Guryev OL; Usanov SA; Estabrook RW
An enzymatically active chimeric protein containing the hydrophilic form of NADPH-cytochrome p450 reductase fused to the membrane-binding domain of cytochrome b(5) | 1 | 1
|
| 12348 | 10 | 12348 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 285(1):32-39
Meyer RP; Hagemeyer CE; Knoth R; Kurz G; Volk B
Oxidative hydrolysis of scoparone by cytochrome P450CYP2C29 reveals a novel metabolite | 1 | 1
|
| 12349 | 10 | 12349 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 286(1):55-60
Iwano S; Saito T; Takahashi Y; Fujita K; Kamataki T
Cooperative regulation of CYP3A5 gene transcription by NF-Y and Sp family members | 4 | 0
|
| 12350 | 7 | 12350 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 286(2):239-242
Tamasi V; Kiss A; Dobozy O; Falus A; Vereczkey L; Monostory K
The effect of dexamethasone on P450 activities in regenerating rat liver | 2 | 1
|
| 12351 | 8 | 12351 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 286(3):652-658
Maier T; Forster HH; Asperger O; Hahn U
Molecular characterization of the 56-kDa CYP153 from Acinetobacter sp EB104 | 1 | 0
|
| 12352 | 20 | 12352 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 287(4):820-824
Nakayama K; Sudo Y; Sasaki Y; Iwata H; Takahashi M; Kamataki T
Studies on transcriptional regulation of Cyp3a16 gene in mouse livers by application of direct DNA injection method | 1 | 0
|
| 12353 | 11 | 12353 2001 BIOCHEMICAL PHARMACOLOGY 61(2):145-153
Borlak J; Thum T
Induction of nuclear transcription factors, cytochrome P450 monooxygenases, and glutathione S-transferase alpha gene expression in Aroclor 1254-treated rat hepatocyte cultures | 6 | 1
|
| 12354 | 25 | 12354 2001 BIOCHEMICAL PHARMACOLOGY 62(2):161-169
Jarukamjorn K; Sakuma T; Yamamoto M; Ohara A; Nemoto N
Sex-associated expression of mouse hepatic and renal CYP2B enzymes by glucocorticoid hormones | 3 | 0
|
| 12355 | 10 | 12355 2001 BIOCHEMICAL PHARMACOLOGY 62(2):249-254
Kikuta Y; Kusunose E; Kusunose M
Expression and induction of cytochrome P450s in rabbit parotid glands | 0 | 0
|
| 12356 | 7 | 12356 2001 BIOCHEMICAL PHARMACOLOGY 62(4):407-415
Oliw EH; Stark K; Bylund J
Oxidation of prostaglandin H-2 and prostaglandin H-2 analogues by human cytochromes P450: analysis of omega-side chain hydroxy metabolites and four steroisomers of 5-hydroxyprostaglandin I-1 by mass spectrometry | 4 | 1
|
| 12357 | 34 | 12357 2001 BIOCHEMICAL PHARMACOLOGY 62(5):635-645
Sivapathasundaram S; Magnisali P; Coldham NG; Howells LC; Sauer MJ; Ioannides C
A study of the expression of the xenobiotic-metabolising cytochrome P450 proteins and of testosterone metabolism in bovine liver | 3 | 1
|
| 12358 | 23 | 12358 2001 BIOCHEMICAL SOCIETY TRANSACTIONS 29():128-135
Urban P; Jobert AS; Laine R; Pompon D
Cytochrome P450 (CYP) mutants and substrate-specificity alterations: segment-directed mutagenesis applied to human CYP1A1 | 1 | 1
|
| 12359 | 14 | 12359 2001 BIOCHEMICAL SOCIETY TRANSACTIONS 29():139-147
Degtyarenko KN; Kulikova TA
Evolution of bioinorganic motifs in P450-containing systems | 4 | 0
|
| 12360 | 12 | 12360 2001 BIOCHEMISTRY 40(7):1956-1963
Munro AW; Noble MA; Robledo L; Daff SN; Chapman SK
Determination of the redox properties of human NADPH-cytochrome P450 reductase | 13 | 2
|
| 12361 | 11 | 12361 2001 BIOCHEMISTRY 40(9):2669-2677
Lee DS; Park SY; Yamane K; Obayashi E; Hori H; Shiro Y
Structural characterization of n-butyl-isocyanide complexes of cytochromes P450nor and P450cam | 5 | 2
|
| 12362 | 18 | 12362 2001 BIOCHEMISTRY 40(14):4521-4530
Yun CH; Miller GP; Guengerich FP
Oxidations of p-alkoxyacylanilides catalyzed by human cytochrome P450 1A2: Structure-activity relationships and simulation of rate constants of individual steps in catalysis | 4 | 3
|
| 12363 | 49 | 12363 2001 BIOCHEMISTRY 40(16):5018-5031
Guryev OL; Gilep AA; Usanov SA; Estabrook RW
Interaction of apo-cytochrome b(5) with cytochromes P4503A4 and P45017A: Relevance of heme transfer reactions | 12 | 12
|
| 12364 | 2 | 12364 2001 BIOCHEMISTRY 40(20):6124-6131
Rasmussen T; Scheide D; Brors B; Kintscher L; Weiss H; Friedrich T
Identification of two tetranuclear FeS clusters on the ferredoxin-type subunit of NADH : ubiquinone oxidoreductase (complex I) | 12 | 0
|
| 12365 | 15 | 12365 2001 BIOCHEMISTRY 40(24):7253-7261
Kent UM; Roberts-Kirchhoff ES; Moon N; Dunham WR; Hollenberg PF
Spectral studies of tert-butyl isothiocyanate-inactivated P450 2E1 | 4 | 1
|
| 12366 | 16 | 12366 2001 BIOCHEMISTRY 40(24):7262-7272
Miller GP; Guengerich FP
Binding and oxidation of alkyl 4-nitrophenyl ethers by rabbit cytochrome P450 1A2: Evidence for two binding sites | 9 | 4
|
| 12367 | 13 | 12367 2001 BIOCHEMISTRY 40(25):7621-7629
Pikuleva IA; Puchkaev A; Bjorkhem I
Putative helix F contributes to regioselectivity of hydroxylation in mitochondrial cytochrome P450 27A1 | 6 | 1
|
| 12368 | 9 | 12368 2001 BIOCHEMISTRY 40(38):11490-11501
Kupfer R; Liu SY; Allentoff AJ; Thompson JA
Comparisons of hydroperoxide isomerase and monooxygenase activities of cytochrome P450 for conversions of allylic hydroperoxides and alcohols to epoxyalcohols and diols: Probing substrate reorientation in the active site | 3 | 1
|
| 12369 | 11 | 12369 2001 BIOCHEMISTRY 40(45):13421-13429
Ost TWB; Miles CS; Munro AW; Murdoch J; Reid GA; Chapman SK
Phenylalanine 393 exerts thermodynamic control over the heme of flavocytochrome P450BM3 | 7 | 6
|
| 12370 | 11 | 12370 2001 BIOCHEMISTRY 40(45):13430-13438
Ost TWB; Munro AW; Mowat CG; Taylor PR; Pesseguiero A; Fulco AJ; Cho AK; Cheesman MA; Walkinshaw MD; Chapman SK
Structural and spectroscopic analysis of the F393H mutant of flavocytochrome p450 BM3 | 3 | 2
|
| 12371 | 25 | 12371 2001 BIOCHEMISTRY 40(45):13456-13465
Haines DC; Tomchick DR; Machius M; Peterson JA
Pivotal role of water in the mechanism of P450BM-3 | 9 | 5
|
| 12372 | 10 | 12372 2001 BIOCHEMISTRY 40(45):13574-13582
Bewley MC; Marohnic CC; Barber MJ
The structure and biochemistry of NADH-dependent cytochrome b(5) reductase are now consistent | 3 | 1
|
| 12373 | 5 | 12373 2001 BIOCHEMISTRY 40(46):14089-14097
Miyano K; Ogasawara S; Han CH; Fukuda H; Tamura M
A fusion protein between Rac and p67(phox) (1-210) reconstitutes NADPH oxidase with higher activity and stability than the individual components | 6 | 0
|
| 12374 | 10 | 12374 2001 BIOCHEMISTRY 40(47):14215-14223
Miller GP; Hanna IH; Nishimura Y; Guengerich FP
Oxidation of phenethylamine derivatives by cytochrome P450 2D6: The issue of substrate protonation in binding and catalysis | 9 | 5
|
| 12375 | 3 | 12375 2001 BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1503(3):329-340
Dejean L; Beauvoit B; Bunoust O; Fleury C; Guerin B; Rigoulet M
The calorimetric-respirometric ratio is an on-line marker of enthalpy efficiency of yeast cells growing on a non-fermentable carbon source | 1 | 0
|
| 12376 | 7 | 12376 2001 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1545(1-2):114-121
Li QS; Schwaneberg U; Fischer M; Schmitt J; Pleiss J; Lutz-Wahl S; Schmid RD
Rational evolution of a medium chain-specific cytochrome P-450 BM-3 variant | 14 | 5
|
| 12377 | 21 | 12377 2001 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1546(1):143-155
Schulz TG; Thiel R; Neubert D; Brassil PJ; Schulz-Utermoehl T; Boobis AR; Edwards RJ
Assessment of P450 induction in the marmoset monkey using targeted anti-peptide antibodies | 3 | 0
|
| 12378 | 4 | 12378 2001 BIOLOGICAL & PHARMACEUTICAL BULLETIN 24(6):678-682
Asano T; Kushida H; Sadakane C; Ishihara K; Wakui Y; Yanagisawa T; Kimura M; Kamei H; Yoshida T
Metabolism of ipecac alkaloids cephaeline and emetine by human hepatic microsomal cytochrome P450s, and their inhibitory effects on P450 enzyme activities | 2 | 0
|
| 12379 | 12 | 12379 2001 BIOLOGICAL & PHARMACEUTICAL BULLETIN 24(8):954-957
Nakamura T; Saito Y; Murayama N; Saeki M; Soyama A; Sai K; Ozawa S; Sawada J
Apparent low frequency of sequence variability within the proximal promoter region of the cytochrome P450 (CYP) 3A5 gene in established cell lines from Japanese individuals | 4 | 0
|
| 12380 | 7 | 12380 2001 BIOLOGICAL & PHARMACEUTICAL BULLETIN 24(11):1263-1266
Washio T; Arisawa H; Kohsaka K; Yasuda H
Identification of human drug-metabolizing enzymes involved in the metabolism of SNI-2011 | 2 | 0
|
| 12381 | 10 | 12381 2001 BIOLOGICAL CHEMISTRY 382(11):1541-1549
Winter J; Eckerskorn C; Waditschatka R; Kayser H
A microsomal ecdysone-binding cytochrome P450 from the insect Locusta migratoria purified by sequential use of type-II and type-I ligands | 1 | 0
|
| 12382 | 19 | 12382 2001 BIOLOGY OF THE NEONATE 80(3):193-201
Hakkola J; Raunio H; Purkunen R; Saarikoski S; Vahakangas K; Pelkonen O; Edwards RJ; Boobis AR; Pasanen M
Cytochrome P450 3A expression in the human fetal liver: Evidence that CYP3A5 is expressed in only a limited number of fetal livers | 4 | 1
|
| 12383 | 1 | 12383 2001 BIOMEDICAL CHROMATOGRAPHY 15(2):141-144
Yao TW; Zeng S
Stereoselective determination of p-hydroxyphenylphenylhydantoin enantiomers in rat liver microsomal incubates by reversed-phase high-performance liquid chromatography using beta-cyclodextrin as chiral mobile phase additives | 3 | 0
|
| 12384 | 3 | 12384 2001 BIOMETALS 14(2):135-142
Matsuo T; Ikeda A; Seki H; Ichimata T; Sugimori D; Nakamura S
Cloning and expression of the ferredoxin gene from extremely halophilic archaeon Haloarcula japonica strain TR-1 | 0 | 0
|
| 12385 | 5 | 12385 2001 BIOPHYSICAL JOURNAL 80(2):626-634
Reijenga KA; Snoep JL; Diderich JA; van Verseveld HW; Westerhoff HV; Teusink B
Control of glycolytic dynamics by hexose transport in Saccharomyces cerevisiae | 5 | 2
|
| 12386 | 2 | 12386 2001 BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 65(11):2548-2551
Ueta E; Suzuki E; Nanba E; Tadokoro Y; Otsuka Y; Kurata T
Regulation of cigarette smoke-induced cytochrome P4501A1 gene expression in osteogenic disorder shionogi rat liver and in lung by large ascorbic acid dose | 1 | 0
|
| 12387 | 10 | 12387 2001 BLOOD 97(4):1106-1114
Dekker J; Eppink MHM; van Zwieten R; de Rijk T; Remacha AF; Law LK; Li AM; Cheung KL; van Berkel WJH; Roos D
Seven new mutations in the nicotinamide adenine dinucleotide reduced-cytochrome b(5) reductase gene leading to methemoglobinemia type I | 5 | 2
|
| 12388 | 2 | 12388 2001 BRAIN RESEARCH 895(1-2):264-267
Jevtovic-Todorovic V; Wozniak DF; Benshoff ND; Olney JW
A comparative evaluation of the neurotoxic properties of ketamine and nitrous oxide | 6 | 0
|
| 12389 | 21 | 12389 2001 BREAST CANCER RESEARCH AND TREATMENT 70(1):47-54
Iscan M; Klaavuniemi T; Coban T; Kapucuoglu N; Pelkonen O; Raunio H
The expression of cytochrome P450 enzymes in human breast tumours and normal breast tissue | 3 | 0
|
| 12390 | 3 | 12390 2001 BRITISH JOURNAL OF CANCER 84(1):42-47
Malingre MM; Beijnen JH; Rosing H; Koopman FJ; Jewell RC; Paul EM; Huinink WWT; Schellens JHM
Co-administration of GF120918 significantly increases the systemic exposure to oral paclitaxel in cancer patients | 16 | 1
|
| 12391 | 9 | 12391 2001 BRITISH JOURNAL OF CANCER 85(2):242-246
McFadyen MCE; Cruickshank ME; Miller ID; McLeod HL; Melvin WT; Haites NE; Parkin D; Murray GI
Cytochrome P450CYP1B1 over-expression in primary and metastatic ovarian cancer | 4 | 1
|
| 12392 | 5 | 12392 2001 BRITISH JOURNAL OF DERMATOLOGY 144(6):1127-1132
Tantcheva-Poor I; Servera-Llaneras M; Scharffetter-Kochanek K; Fuhr U
Liver cytochrome P450CYP1A2 is markedly inhibited by systemic but not by bath PUVA in dermatological patients | 0 | 0
|
| 12393 | 3 | 12393 2001 CANCER CHEMOTHERAPY AND PHARMACOLOGY 47(4):347-354
Malingre MM; Beijnen JH; Rosing H; Koopman FJ; van Tellingen O; Duchin K; Huinink WWT; Swart M; Lieverst J; Schellens JHM
A phase I and pharmacokinetic study of bi-daily dosing of oral paclitaxel in combination with cyclosporin A | 4 | 1
|
| 12394 | 3 | 12394 2001 CANCER CHEMOTHERAPY AND PHARMACOLOGY 48(2):115-122
Nallani SC; Genter MB; Desai PB
Increased activity of CYP3A enzyme in primary cultures of rat hepatocytes treated with docetaxel: comparative evaluation with paclitaxel | 5 | 1
|
| 12395 | 4 | 12395 2001 CANCER LETTERS 163(2):179-185
Masuda C; Wanibuchi H; Otori K; Wei M; Yamamoto S; Hiroi T; Imaoka S; Funae Y; Fukushima S
Presence of a no-observed effect level for enhancing effects of development of the alpha-isomer of benzene hexachloride (alpha- BHC) on diethylnitrosamine-initiated hepatic foci in rats | 2 | 0
|
| 12396 | 9 | 12396 2001 CANCER LETTERS 165(1):95-101
Jeong HG; Kim JY; Choi CY; You HJ; Hahm KS
Suppression of CYP1A1 expression by 4-nonylphenol in murine Hepa-1c1c7 cells | 2 | 0
|
| 12397 | 8 | 12397 2001 CARCINOGENESIS 22(3):481-488
Vondracek M; Xi Z; Larsson P; Baker V; Mace K; Pfeifer A; Tjalve H; Donato MT; Gomez-Lechon MJ; Grafstrom RC
Cytochrome P450 expression and related metabolism in human buccal mucosa | 3 | 0
|
| 12398 | 11 | 12398 2001 CARCINOGENESIS 22(3):499-506
Teiber JF; Mace K; Hollenberg PF
Metabolism of the beta-oxidized intermediates of N-nitrosodi-n- propylamine: N-nitroso-beta-hydroxypropylpropylamine and N- nitroso-beta-oxopropylpropylamine | 1 | 1
|
| 12399 | 10 | 12399 2001 CARCINOGENESIS 22(5):763-770
Hudson CE; Schulte BA; Sutter TR; Norris JS
Steroid hormones modulate expression of cytochrome P450 enzymes in male hamster reproductive tract and leiomyosarcomas | 1 | 0
|
| 12400 | 7 | 12400 2001 CARCINOGENESIS 22(6):943-950
Yueh MF; Nguyen N; Famourzadeh M; Strassburg CP; Oda Y; Guengerich FP; Tukey RH
The contribution of UDP-glucuronosyltransferase 1A9 on CYP1A2- mediated genotoxicity by aromatic and heterocyclic amines | 7 | 0
|
| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 12401 | 3 | 12401 2001 CARCINOGENESIS 22(11):1819-1824
Cauchi S; Stucker I; Solas C; Laurent-Puig P; Cenee S; Hemon D; Jacquet M; Kremers P; Beaune P; Massaad-Massade L
Polymorphisms of human aryl hydrocarbon receptor (AhR) gene in a French population: relationship with CYP1A1 inducibility and lung cancer | 8 | 1
|
| 12402 | 11 | 12402 2001 CARCINOGENESIS 22(11):1877-1883
Pinto LFR; Moraes E; Albano RM; Silva MC; Godoy W; Glisovic T; Lang MA
Rat oesophageal cytochrome P450 (CYP) monooxygenase system: comparison to the liver and relevance in N-nitrosodiethylamine carcinogenesis | 2 | 0
|
| 12403 | 10 | 12403 2001 CARCINOGENESIS 22(12):2033-2038
Hatanaka N; Yamazaki H; Kizu R; Hayakawa K; Aoki Y; Iwanari M; Nakajima M; Yokoi T
Induction of cytochrome P4501B1 in lung, liver and kidney of rats exposed to diesel exhaust | 4 | 1
|
| 12404 | 11 | 12404 2001 CELL BIOLOGY AND TOXICOLOGY 17(4):271-285
Testai E
The drug-metabolizing enzymatic system and the experimental tools used for in vitro toxicology for metabolic studies | 0 | 0
|
| 12405 | 6 | 12405 2001 CELL BIOLOGY AND TOXICOLOGY 17(4):287-299
Battle T; Stacey G
Cell culture models for hepatotoxicology | 0 | 0
|
| 12406 | 4 | 12406 2001 CELLULAR AND MOLECULAR BIOLOGY 47(8):1309-1318
Vindimian E
The biological monitoring of toxic impacts on the environment | 0 | 0
|
| 12407 | 27 | 12407 2001 CELLULAR AND MOLECULAR LIFE SCIENCES 58(5-6):737-747
Anzenbacher P; Anzenbacherova E
Cytochromes P450 and metabolism of xenobiotics | 22 | 1
|
| 12408 | 8 | 12408 2001 CHEMICAL RESEARCH IN TOXICOLOGY 14(4):338-347
Atkins WM; Wang RW; Lu AYH
Allosteric behavior in cytochrome P450-dependent in vitro drug- drug interactions: A prospective based on conformational dynamics | 18 | 5
|
| 12409 | 85 | 12409 2001 CHEMICAL RESEARCH IN TOXICOLOGY 14(6):611-650
Guengerich FP
Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity | 47 | 12
|
| 12410 | 7 | 12410 2001 CHEMICAL RESEARCH IN TOXICOLOGY 14(7):901-911
Turesky RJ; Parisod V; Huynh-Ba T; Langouet S; Guengerich FP
Regioselective differences in C-8- and N-oxidation of 2-amino- 3,8-dimethylimidazo [4,5-f]quinoxaline by human and rat liver microsomes and cytochromes p450 1A2 | 2 | 0
|
| 12411 | 14 | 12411 2001 CHEMICKE LISTY 95(4):212-222
Chroma L; Mackova M; Macek T; Martinek V; Stiborova M
Plant cytochromes P450 and peroxidases and their role in degradation of environmental contaminants | 0 | 0
|
| 12412 | 24 | 12412 2001 CHEMICO-BIOLOGICAL INTERACTIONS 138(1):85-106
Boek-Dohalska L; Hodek P; Sulc M; Stiborova M
alpha-naphthoflavone acts as activator and reversible or irreversible inhibitor of rabbit microsomal CYP3A6 | 1 | 0
|
| 12413 | 3 | 12413 2001 CHEMICO-BIOLOGICAL INTERACTIONS 138(3):217-229
Gaikwad NW; Bodell WJ
Formation of DNA adducts by microsomal and peroxidase activation of p-cresol: role of quinone methide in DNA adduct formation | 2 | 0
|
| 12414 | 9 | 12414 2001 CHEMICO-BIOLOGICAL INTERACTIONS 138(3):285-298
Navas JM; Segner H
Estrogen-mediated suppression of cytochrome P4501A (CYP1A) expression in rainbow trout hepatocytes: role of estrogen receptor | 2 | 0
|
| 12415 | 5 | 12415 2001 CHEST 120(2):634-+
Clay AS; Behnia M; Brown KK
Mitochondrial disease - A pulmonary and critical-care medicine perspective | 2 | 1
|
| 12416 | 3 | 12416 2001 CHINESE JOURNAL OF PHYSIOLOGY 44(3):111-119
Yang JG; Yu CC; Li PS
Dexamethasone enhances follicle stimulating hormone-induced p450scc mRNA expression and progesterone production in pig granulosa cells | 0 | 0
|
| 12417 | 6 | 12417 2001 CIRCULATION RESEARCH 89(3):224-236
Tarpey MM; Fridovich I
Methods of detection of vascular reactive species - Nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite | 23 | 0
|
| 12418 | 34 | 12418 2001 CIRCULATION RESEARCH 89(9):753-762
Fleming I
Cytochrome P450 enzymes in vascular homeostasis | 22 | 0
|
| 12419 | 5 | 12419 2001 CLINICAL CHEMISTRY 47(2):348-351
Cavalli SA; Hirata MH; Hirata RDC
Detection of MboII polymorphism at the 5 ' promoter region of CYP3A4 | 2 | 2
|
| 12420 | 3 | 12420 2001 CLINICAL CHEMISTRY 47(6):1104-1106
van Schaik RHN; de Wildt SN; Brosens R; van Fessem M; van den Anker JN; Lindemans J
The CYP3A4*3 allele: Is it really rare? | 2 | 0
|
| 12421 | 14 | 12421 2001 CLINICAL PHARMACOKINETICS 40(9):631-640
Bonnabry P; Sievering J; Leemann T; Dayer P
Quantitative drug interactions prediction system (Q-DIPS) - A dynamic computer-based method to assist in the choice of clinically relevant in vivo studies | 3 | 0
|
| 12422 | 15 | 12422 2001 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY 128(1):99-112
Nyman M; Raunio H; Taavitsainen P; Pelkonen O
Characterization of xenobiotic-metabolizing cytochrome P450 (CYP) forms in ringed and grey seals from the Baltic Sea and reference sites | 3 | 2
|
| 12423 | 16 | 12423 2001 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY 128(2):281-290
Arinc E; Kocabiyik S; Su E
Induced CYP1A mRNA, protein and catalytic activity in the liver of feral fish, leaping mullet, Liza saliens | 2 | 2
|
| 12424 | 20 | 12424 2001 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY 128(3):367-376
Stupans I; Jones B; McKinnon RA
Xenobiotic metabolism in Australian marsupials | 0 | 0
|
| 12425 | 13 | 12425 2001 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY 129(2):115-127
Craft JA; Robertson FE; McPhail ME; Brown E; Stagg RM
Measurement of cytochrome P4501A induction in dab (Limanda limanda) and other teleosts with species-specific cDNA probes: isolation and characterisation of dab cDNA and its use in expression studies with beta-naphthoflavone-treated fish | 2 | 0
|
| 12426 | 19 | 12426 2001 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY 130(1):133-144
Pretti C; Salvetti A; Longo V; Giorgi M; Gervasi PG
Effects of beta-naphthoflavone on the cytochrome P450 system, and phase II enzymes in gilthead seabream (Sparus aurata) | 0 | 0
|
| 12427 | 4 | 12427 2001 CONTRACEPTION 64(4):261-269
Ghosh R; Kamboj VP; Singh MM
Interaction with anti-implantation and estrogen antagonistic activities of dl-ormeloxifene, a selective estrogen receptor modulator, by tetracycline in female Sprague-Dawley rats | 0 | 0
|
| 12428 | 28 | 12428 2001 CURRENT DRUG METABOLISM 2(1):1-16
Vaz ADN
Multiple oxidants in cytochrome P450 catalyzed reactions: Implications for drug metabolism | 1 | 0
|
| 12429 | 16 | 12429 2001 CURRENT DRUG METABOLISM 2(1):17-36
Shou M; Lin Y; Lu P; Tang C; Mei Q; Cui D; Tang W; Ngui JS; Lin CC; Singh R; Wong BK; Yergey JA; Lin JH; Pearson PG; Baillie TA; Rodrigues AD; Rushmore TH
Enzyme kinetics of cytochrome P450-mediated reactions | 10 | 3
|
| 12430 | 25 | 12430 2001 CURRENT DRUG METABOLISM 2(2):93-115
Guengerich FP
Uncommon P450-catalyzed reactions | 3 | 0
|
| 12431 | 14 | 12431 2001 CURRENT DRUG METABOLISM 2(2):149-164
Ma Q
Induction of CYP1A1. The AhR/DRE paradigm: Transcription, receptor regulation, and expanding biological roles | 17 | 4
|
| 12432 | 56 | 12432 2001 CURRENT DRUG METABOLISM 2(3):245-263
Hedlund E; Gustafsson JA; Warner M
Cytochrome P450 in the brain; A review | 5 | 0
|
| 12433 | 7 | 12433 2001 CURRENT OPINION IN PLANT BIOLOGY 4(2):162-167
Feldmann KA
Cytochrome P450s as genes for crop improvement | 7 | 2
|
| 12434 | 4 | 12434 2001 CURRENT OPINION IN PLANT BIOLOGY 4(3):225-233
De Luca V; Laflamme P
The expanding universe of alkaloid biosynthesis | 5 | 0
|
| 12435 | 3 | 12435 2001 DIGESTION 63(2):69-91
Braganza JM
Towards a novel treatment strategy for acute pancreatitis - 1. Reappraisal of the evidence on aetiogenesis | 4 | 0
|
| 12436 | 2 | 12436 2001 DRUG AND CHEMICAL TOXICOLOGY 24(4):429-437
Ebrahim AS; Babu E; Thirunavukkarasu C; Sakthisekaran D
Protective role of vitamin E, 2-deoxy-D-glucose, and taurine on perchloroethylene induced alterations in ATPases | 0 | 0
|
| 12437 | 8 | 12437 2001 DRUG METABOLISM AND DISPOSITION 29(1):4-7
Sheng JJ; Hua ZC; Guo JC; Caggana M; Ding XX
Identification of a new human CYP2A gene fragment with close linkage to CYP2GP1 | 7 | 2
|
| 12438 | 7 | 12438 2001 DRUG METABOLISM AND DISPOSITION 29(2):200-205
Miyazawa M; Shindo M; Shimada T
Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus Polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes | 8 | 2
|
| 12439 | 14 | 12439 2001 DRUG METABOLISM AND DISPOSITION 29(3):217-222
Taavitsainen P; Juvonen R; Pelkonen O
In vitro inhibition of cytochrome P450 enzymes in human liver microsomes by a potent CYP2A6 inhibitor, trans-2- phenylcyclopropylamine (tranylcypromine), and its nonamine analog, cyclopropylbenzene | 12 | 2
|
| 12440 | 11 | 12440 2001 DRUG METABOLISM AND DISPOSITION 29(3):268-273
Hsieh KP; Lin YY; Cheng CL; Lai ML; Lin MS; Siest JP; Huang JD
Novel mutations of CYP3A4 in Chinese | 12 | 5
|
| 12441 | 13 | 12441 2001 DRUG METABOLISM AND DISPOSITION 29(3):304-312
Yu LJ; Matias J; Scudiero DA; Hite KM; Monks A; Sausville EA; Waxman DJ
P450 enzyme expression patterns in the NCI human tumor cell line panel | 12 | 3
|
| 12442 | 18 | 12442 2001 DRUG METABOLISM AND DISPOSITION 29(3):353-360
Kim H; Putt DA; Zangar RC; Wolf CR; Guengerich FP; Edwards RJ; Hollenberg PF; Novak RF
Differential induction of rat hepatic cytochromes P450 3A1, 3A2, 2B1, 2B2, and 2E1 in response to pyridine treatment | 3 | 1
|
| 12443 | 15 | 12443 2001 DRUG METABOLISM AND DISPOSITION 29(4):368-374
Lin Y; Lu P; Tang C; Mei Q; Sandig G; Rodrigues AD; Rushmore TH; Shou M
Substrate inhibition kinetics for cytochrome P450-catalyzed reactions | 13 | 3
|
| 12444 | 15 | 12444 2001 DRUG METABOLISM AND DISPOSITION 29(5):615-622
Quattrochi LC; Guzelian PS
CYP3A regulation: From pharmacology to nuclear receptors | 27 | 11
|
| 12445 | 27 | 12445 2001 DRUG METABOLISM AND DISPOSITION 29(5):623-633
Hines RN; Luo Z; Cresteil T; Ding X; Prough RA; Fitzpatrick JL; Ripp SL; Falkner KC; Ge NL; Levine A; Elferink CJ
Molecular regulation of genes encoding xenobiotic-metabolizing enzymes: Mechanisms involving endogenous factors | 5 | 3
|
| 12446 | 1 | 12446 2001 DRUG METABOLISM AND DISPOSITION 29(6):779-780
Murphy PJ
Xenobiotic metabolism: A look from the past to the future | 0 | 0
|
| 12447 | 14 | 12447 2001 DRUG METABOLISM AND DISPOSITION 29(6):798-805
Hashizume T; Mise M; Matsumoto S; Terauchi Y; Fujii T; Imaoka S; Funae Y; Kamataki T; Miyazaki H
A novel cytochrome P450 enzyme responsible for the metabolism of ebastine in monkey small intestine | 1 | 1
|
| 12448 | 21 | 12448 2001 DRUG METABOLISM AND DISPOSITION 29(6):837-842
Turan VK; Mishin VM; Thomas PE
Clotrimazole is a selective and potent inhibitor of rat cytochrome P450 3A subfamily-related testosterone metabolism | 0 | 0
|
| 12449 | 11 | 12449 2001 DRUG METABOLISM AND DISPOSITION 29(6):908-915
Myers MJ; Farrell DE; Howard KD; Kawalek JC
Identification of multiple constitutive and inducible hepatic cytochrome P450 enzymes in market weight swine | 5 | 0
|
| 12450 | 17 | 12450 2001 DRUG METABOLISM AND DISPOSITION 29(7):983-989
Fujita K; Kamataki T
Screening of organosulfur compounds as inhibitors of human CYP2A6 | 2 | 0
|
| 12451 | 3 | 12451 2001 DRUG METABOLISM AND DISPOSITION 29(7):1068-1072
Ishigami M; Kawabata K; Takasaki W; Ikeda T; Komai T; Ito K; Sugiyama Y
Drug interaction between simvastatin and itraconazole in male and female rats | 3 | 1
|
| 12452 | 9 | 12452 2001 DRUG METABOLISM AND DISPOSITION 29(8):1146-1155
Subrahmanyam V; Renwick AB; Walters DG; Young PJ; Price RJ; Tonelli AP; Lake BG
Identification of cytochrome P-450 isoforms responsible for cis-tramadol metabolism in human liver microsomes | 3 | 0
|
| 12453 | 8 | 12453 2001 DRUG METABOLISM AND DISPOSITION 29(9):1243-1250
Burczynski ME; McMillian M; Parker JB; Bryant S; Leone A; Grant ER; Thorne JM; Zhong Z; Zivin RA; Johnson MD
Cytochrome P450 induction in rat hepatocytes assessed by quantitative real-time reverse-transcription polymerase chain reaction and the RNA invasive cleavage assay | 4 | 2
|
| 12454 | 7 | 12454 2001 DRUG METABOLISM AND DISPOSITION 29(11):1403-1409
Kuperman AV; Kalgutkar AS; Marfat A; Chambers RJ; Liston TE
Pharmacokinetics and metabolism of a cysteinyl leukotriene-1 receptor antagonist from the heterocyclic chromanol series in rats: In vitro-in vivo correlation, gender-related differences, isoform identification, and comparison with metabolism in human hepatic tissue | 2 | 0
|
| 12455 | 15 | 12455 2001 DRUG METABOLISM AND DISPOSITION 29(11):1499-1504
El-Sankary W; Gibson GG; Ayrton A; Plant N
Use of a reporter gene assay to predict and rank the potency and efficacy of CYP3A4 inducers | 7 | 0
|
| 12456 | 10 | 12456 2001 DRUG METABOLISM REVIEWS 33(1):1-35
Miller KP; Ramos KS
Impact of cellular metabolism on the biological effects of benzo[a]pyrene and related hydrocarbons | 7 | 0
|
| 12457 | 17 | 12457 2001 DRUG METABOLISM REVIEWS 33(1):81-116
Mannering GJ
A life in science: Biochemist-nutritionist-forensic toxicologst-pharmacologist | 0 | 0
|
| 12458 | 6 | 12458 2001 DRUG METABOLISM REVIEWS 33(3-4):255-271
Kong ANT; Owuor E; Yu R; Hebbar V; Chen C; Hu R; Mandlekar S
Induction of xenobiotic enzymes by the map kinase pathway and the antioxidant or electrophile response element (ARE/EpRE) | 14 | 0
|
| 12459 | 25 | 12459 2001 EMBO JOURNAL 20(10):2394-2403
Anandatheerthavarada HK; Amuthan G; Biswas G; Robin MA; Murali R; Waterman MR; Avadhani NG
Evolutionarily divergent electron donor proteins interact with P450MT2 through the same helical domain but different contact points | 1 | 0
|
| 12460 | 17 | 12460 2001 ENDOCRINOLOGY 142(6):2569-2576
Huang MC; Miller WL
Creation and activity of COS-1 cells stably expressing the F2 fusion of the human cholesterol side-chain cleavage enzyme system | 1 | 0
|
| 12461 | 13 | 12461 2001 ENDOCRINOLOGY 142(9):3901-3908
Hiroi T; Kishimoto W; Chow T; Imaoka S; Igarashi TS; Funae Y
Progesterone oxidation by cytochrome P450 2D isoforms in the brain | 11 | 5
|
| 12462 | 14 | 12462 2001 ENDOCRINOLOGY 142(11):4589-4594
Simpson ER; Davis SR
Minireview: Aromatase and the regulation of estrogen biosynthesis - Some new perspectives | 17 | 3
|
| 12463 | 4 | 12463 2001 ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA 30(1):1-+
New MI
Prenatal treatment of congenital adrenal hyperplasia - The United States experience | 3 | 0
|
| 12464 | 11 | 12464 2001 ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA 30(1):61-+
White PC
Steroid 11 beta-hydroxylase deficiency and related disorders | 7 | 1
|
| 12465 | 31 | 12465 2001 ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA 30(1):101-+
Auchus RJ
The genetics, pathophysiology, and management of human deficiencies of P450c17 | 2 | 1
|
| 12466 | 19 | 12466 2001 ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 38(1):12-18
Josephy PD; Batty SM; Boverhof DR
Recombinant human P450 forms 1A1, 1A2, and 1B1 catalyze the bioactivation of heterocyclic amine mutagens in Escherichia coli lacZ strains | 2 | 1
|
| 12467 | 31 | 12467 2001 ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 38(4):329-338
Fujita K; Nakayama K; Yamazaki Y; Tsuruma K; Yamada M; Nohmi T; Kamataki T
Construction of Salmonella typhimurium YG7108 strains, each coexpressing a form of human cytochrome P450 with NADPH- cytochrome P450 reductase | 2 | 1
|
| 12468 | 12 | 12468 2001 ENVIRONMENTAL HEALTH PERSPECTIVES 109(1):61-66
Newman JW; Denton DL; Morisseau C; Koger CS; Wheelock CE; Hinton DE; Hammock BD
Evaluation of fish models of soluble epoxide hydrolase inhibition | 3 | 1
|
| 12469 | 2 | 12469 2001 EUROPEAN HEART JOURNAL 22(16):1374-1450
Priori SG; Aliot E; Blomstrom-Lundqvist C; Bossaert L; Breithardt G; Brugada P; Camm AJ; Cappato R; Cobbe SM; Di Mario C; Maron BJ; McKenna WJ; Pedersen AK; Ravens U; Schwartz PJ; Trusz-Gluza M; Vardas P; Wellens HJJ; Zipes DP
Task force on sudden cardiac death of the European Society of Cardiology | 28 | 0
|
| 12470 | 3 | 12470 2001 EUROPEAN HEART JOURNAL SUPPLEMENTS 3(K):K93-K100
Bauman JL
The role of pharmacokinetics, drug interactions and pharmacogenetics in the acquired long QT syndrome | 2 | 0
|
| 12471 | 9 | 12471 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(5):1448-1459
Gomez-Lechon MJ; Donato T; Jover R; Rodriguez C; Ponsoda X; Glaise D; Castell JV; Guguen-Guillouzo C
Expression and induction of a large set of drug-metabolizing enzymes by the highly differentiated human hepatoma cell line BC2 | 6 | 0
|
| 12472 | 10 | 12472 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(10):3083-3090
Le Bouquin R; Skrabs M; Kahn R; Benveniste I; Salaun JP; Schreiber L; Durst F; Pinot F
CYP94A5, a new cytochrome P450 from Nicotiana tabacum is able to catalyze the oxidation of fatty acids to the omega-alcohol and to the corresponding diacid | 2 | 0
|
| 12473 | 20 | 12473 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(10):3117-3125
Carmichael AB; Wong LL
Protein engineering of Bacillus megaterium CYP102 - The oxidation of polycyclic aromatic hydrocarbons | 9 | 4
|
| 12474 | 8 | 12474 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(11):3198-3204
Zhang L; Takaya N; Kitazume T; Kondo T; Shoun H
Purification and cDNA cloning of nitric oxide reductase cytochrome P450nor (CYP55A4) from Trichosporon cutaneum | 5 | 1
|
| 12475 | 14 | 12475 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(14):4095-4103
Weitzel JM; Kutz S; Radtke C; Grott S; Seitz HJ
Hormonal regulation of multiple promoters of the rat mitochondrial glycerol-3-phosphate dehydrogenase gene - Identification of a complex hormone-response element in the ubiquitous promoter B | 6 | 1
|
| 12476 | 75 | 12476 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(18):4817-4832
Hlavica P; Lewis DFV
Allosteric phenomena in cytochrome P450-catalyzed monooxygenations | 2 | 1
|
| 12477 | 16 | 12477 2001 EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 31(10):880-886
Finnstrom N; Bjelfman C; Soderstrom TG; Smith G; Egevad L; Norlen BJ; Wolf CR; Rane A
Detection of cytochrome P450 mRNA transcripts in prostate samples by RT-PCR | 2 | 0
|
| 12478 | 9 | 12478 2001 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 57(5):403-409
Finnstrom N; Thorn M; Loof L; Rane A
Independent patterns of cytochrome P-450 gene expression in liver and blood in patients with suspected liver disease | 6 | 1
|
| 12479 | 4 | 12479 2001 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 26(1-2):31-35
Klinger W; Karge E; Demme U; Kretzschmar M
Interactions of melatonin with the liver microsomal cytochrome P450 system of rats and humans in vitro and effects on the P450 system and the antioxidative status in rat liver after acute treatment | 0 | 0
|
| 12480 | 21 | 12480 2001 EUROPEAN RESPIRATORY JOURNAL 18():122S-126S
Hukkanen J; Pelkonen O; Raunio H
Expression of xenobiotic-metabolizing enzymes in human pulmonary tissue: possible role in susceptibility for ILD | 2 | 0
|
| 12481 | 4 | 12481 2001 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 52(6):513-522
Klinger W; Lupp A; Barth A; Karge E; Knels L; Kuhn U; Muller D; Schiller F; Demme U; Lindstrom-Seppa P; Hanninen O
Cytochrome P450 (P450) isoforms expression, P450 concentration, monooxygenase activities, reactive oxygen species formation, lipid peroxidation, and glutathione content in wild catch carp and tench liver - influence of a two weeks exposure to phenobarbital | 0 | 0
|
| 12482 | 6 | 12482 2001 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 53(5):387-391
Ejiri N; Katayama KI; Nakayama H; Doi K
Expression of cytochrome P450 (CYP) isozymes in rat placenta through pregnancy | 1 | 1
|
| 12483 | 8 | 12483 2001 FARADAY DISCUSSIONS 120():261-276
Dano S; Hynne F; De Monte S; d'Ovidio F; Sorensen PG; Westerhoff H
Synchronization of glycolytic oscillations in a yeast cell population | 0 | 0
|
| 12484 | 2 | 12484 2001 FEMS MICROBIOLOGY LETTERS 198(1):23-29
Maitra PK; Bhosale SB; Kshirsagar DC; Yeole TY; Shanbhag AN
Metabolite and enzyme profiles of glycogen metabolism in Methanococcoides methylutens | 2 | 0
|
| 12485 | 6 | 12485 2001 FERTILITY AND STERILITY 76(3):517-524
Attia GR; Rainey WE; Carr BR
Metformin directly inhibits androgen production in human thecal cells | 8 | 0
|
| 12486 | 6 | 12486 2001 FOLIA HISTOCHEMICA ET CYTOBIOLOGICA 39():48-49
Testai E
The relevance of xenobiotic metabolism in the interindividual susceptibility to chemicals | 0 | 0
|
| 12487 | 16 | 12487 2001 FOOD AND CHEMICAL TOXICOLOGY 39(2):125-132
Hannon-Fletcher MPA; O'Kane MJ; Moles KW; Barnett YA; Barnett CR
Lymphocyte cytochrome P450-CYP2E1 expression in human IDDM subjects | 6 | 0
|
| 12488 | 7 | 12488 2001 FOOD AND CHEMICAL TOXICOLOGY 39(7):667-680
Walton K; Dorne JL; Renwick AG
Uncertainty factors for chemical risk assessment: interspecies differences in the in vivo pharmacokinetics and metabolism of human CYP1A2 substrates | 9 | 0
|
| 12489 | 17 | 12489 2001 FUNGAL GENETICS AND BIOLOGY 33(1):37-48
George HL; VanEtten HD
Characterization of pisatin-inducible cytochrome P450s in fungal pathogens of pea that detoxify the pea phytoalexin pisatin | 2 | 1
|
| 12490 | 6 | 12490 2001 FUNGAL GENETICS AND BIOLOGY 34(3):155-165
Seo JA; Proctor RH; Plattner RD
Characterization of four clustered and coregulated genes associated with fumonisin biosynthesis in Fusarium verticillioides | 9 | 2
|
| 12491 | 1 | 12491 2001 GASTROENTEROLOGY 120(2):525-533
Kullak-Ublick GA; Ismair MG; Stieger B; Landmann L; Huber R; Pizzagalli F; Fattinger K; Meier PJ; Hagenbuch B
Organic anion-transporting potypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver | 63 | 0
|
| 12492 | 20 | 12492 2001 GENE 262(1-2):189-198
Tijet N; Helvig C; Feyereisen R
The cytochrome P450 gene superfamily in Drosophila melanogaster: Annotation, intron-exon organization and phylogeny | 21 | 2
|
| 12493 | 12 | 12493 2001 GENE 272(1-2):257-266
Wen ZM; Horak CE; Scott JG
CYP9E2, CYP4C21 and related pseudogenes from German cockroaches, Blattella germanica: implications for molecular evolution, expression studies and nomenclature of P450s | 2 | 1
|
| 12494 | 7 | 12494 2001 GENOME RESEARCH 11(5):685-702
Glusman G; Yanai I; Rubin I; Lancet D
The complete human olfactory subgenome | 69 | 0
|
| 12495 | 3 | 12495 2001 HELVETICA CHIMICA ACTA 84(1):172-179
Nezbedova L; Hesse M; Drandarov K; Werner C
Prelandrine, the key-step intermediate in the biosynthesis of the macrocyclic spermine alkaloid aphelandrine | 5 | 1
|
| 12496 | 2 | 12496 2001 HEPATOLOGY 33(4):915-924
DeAngelis RA; Kovalovich K; Cressman DE; Taub R
Normal liver regeneration in p50/nuclear factor kappa B1 knockout mice | 5 | 2
|
| 12497 | 12 | 12497 2001 HISTOCHEMICAL JOURNAL 33(2):101-110
Sarasquete C; Ortiz JB; Gisbert E
Immunohistochemical distribution of cytochrome P4501A in larvae and fingerlings of the Siberian sturgeon, Acipenser baeri | 1 | 0
|
| 12498 | 6 | 12498 2001 HUMAN AND ECOLOGICAL RISK ASSESSMENT 7(1):181-201
Walton K; Dorne JLCM; Renwick AG
Default factors for interspecies differences in the major routes of xenobiotic elimination | 3 | 0
|
| 12499 | 6 | 12499 2001 HUMAN GENETICS 108(2):148-155
Chevalier D; Cauffiez C; Bernard C; Lo-Guidice JM; Allorge D; Fazio F; Ferrari N; Libersa C; Lhermitte M; D'Halluin JC; Broly F
Characterization of new mutations in the coding sequence and 5'-untranslated region of the human prostacyclin synthase gene (CYP8A1) | 9 | 2
|
| 12500 | 16 | 12500 2001 IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 37(3):180-184
Sadar MD; Andersson TB
Regulation of cytochrome P450 in a primary culture of rainbow trout hepatocytes | 0 | 0
|