#	Cited nodes	Nodes / Authors	GCS	LCS
10101	13	10101 1996 CHEMICAL RESEARCH IN TOXICOLOGY 9(1):318-325 Barr DP; Martin MV; Guengerich FP; Mason RP Reaction of cytochrome P450 with cumene hydroperoxide: ESR spin trapping evidence for the homolytic scission of the peroxide O- O bond by ferric cytochrome P450 1A2	24	7
10102	14	10102 1996 CHEMICAL RESEARCH IN TOXICOLOGY 9(4):729-736 Cai YN; BaerDubowska W; AshwoodSmith MJ; Ceska O; Tachibana S; DiGiovanni J Mechanism-based inactivation of hepatic ethoxyresorufin O- dealkylation activity by naturally occurring coumarins	20	0
10103	7	10103 1996 CHEMICAL RESEARCH IN TOXICOLOGY 9(5):871-874 Bellucci G; Chiappe C; Pucci L; Gervasi PG The mechanism of oxidation of allylic alcohols to alpha,beta- unsaturated ketones by cytochrome p450	4	1
10104	17	10104 1996 CHEMICAL RESEARCH IN TOXICOLOGY 9(6):924-931 Anari MR; Khan S; OBrien PJ The involvement of cytochrome P450 peroxidase in the metabolic bioactivation of cumene hydroperoxide by isolated rat hepatocytes	5	1
10105	34	10105 1996 CHEMICAL RESEARCH IN TOXICOLOGY 9(7):1079-1091 deGroot MJ; Vermeulen NPE; Kramer JD; vanAcker FAA; denKelder GMDO A three-dimensional protein model for human cytochrome P450 2D6 based on the crystal structures of P450 101, p450 102, and P450 108	44	26
10106	43	10106 1996 CHEMICAL REVIEWS 96(7):2841-2887 Sono M; Roach MP; Coulter ED; Dawson JH Heme-containing oxygenases	378	19
10107	19	10107 1996 CHEMICO-BIOLOGICAL INTERACTIONS 101(3):175-192 Wormhoudt LW; Ploemen JHTM; deWaziers I; Commandeur JNM; Beaune PH; vanBladeren PJ; Vermeulen NPE Inter-individual variability in the oxidation of 1,2- dibromoethane: Use of heterologously expressed human cytochrome P450 and human liver microsomes	9	3
10108	8	10108 1996 CHEMICO-BIOLOGICAL INTERACTIONS 102(3):155-167 Eke BC; Vural N; Iscan M Combined effects of ethanol and cigarette smoke on hepatic and pulmonary xenobiotic metabolizing enzymes in rats	5	3
10109	8	10109 1996 CHEMOSPHERE 32(7):1357-1380 Eggens ML; Vethaak AD; Leaver MJ; Horbach GJMJ; Boon JP; Seinen W Differences in CYP1A response between flounder (Platichthys flesus) and plaice (Pleuronectes platessa) after long-term exposure to harbour dredged spoil in a mesocosm study	15	2
10110	1	10110 1996 CHEMOSPHERE 32(11):2115-2125 Jenssen BM; Skaare JU Organochlorine compounds in blubber, liver and brain in neonatal grey seal pups	19	0
10111	6	10111 1996 CIRCULATION RESEARCH 79(1):54-61 Harder DR; Narayanan J; Birks EK; Liard JF; Imig JD; Lombard JH; Lange AR; Roman RJ Identification of a putative microvascular oxygen sensor	69	6
10112	21	10112 1996 CIRCULATION RESEARCH 79(4):784-793 Fang X; Kaduce TL; Weintraub NL; VanRollins M; Spector AA Functional implications of a newly characterized pathway of 11,12-epoxyeicosatrienoic acid metabolism in arterial smooth muscle	42	16
10113	10	10113 1996 CLINICAL PHARMACOKINETICS 30(2):141-179 Campana C; Regazzi MB; Buggia I; Molinaro M Clinically significant drug interactions with cyclosporin - An update	76	7
10114	23	10114 1996 CLINICAL PHARMACOKINETICS 31(1):9-28 Andersson T Pharmacokinetics, metabolism and interactions of acid pump inhibitors - Focus on omeprazole, lansoprazole and pantoprazole	113	5
10115	7	10115 1996 CLINICAL PHARMACOKINETICS 31(1):47-64 WalterSack I; Klotz U Influence of diet and nutritional status on drug metabolism	42	4
10116	2	10116 1996 CLINICAL PHARMACOKINETICS 31(3):198-214 Spina E; Pisani F; Perucca E Clinically significant pharmacokinetic drug interactions with carbamazepine - An update	90	5
10117	22	10117 1996 CLINICAL PHARMACOKINETICS 31(3):215-230 Pirmohamed M; Madden S; Park BK Idiosyncratic drug reactions - Metabolic bioactivation as a pathogenic mechanism	33	3
10118	12	10118 1996 CLINICAL PHARMACOLOGY & THERAPEUTICS 59(6):613-623 Engel G; Hofmann U; Heidemann H; Cosme J; Eichelbaum M Antipyrine as a probe for human oxidative drug metabolism: Identification of the cytochrome P450 enzymes catalyzing 4- hydroxyantipyrine, 3-hydromethylantipyrine, and norantipyrine formation	79	12
10119	9	10119 1996 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 113(1):175-183 Zhang ML; Scott JG Purification and characterization of cytochrome b(5) reductase from the house fly, Musca domestica	3	3
10120	2	10120 1996 COMPUTER APPLICATIONS IN THE BIOSCIENCES 12(3):237-240 Degtyarenko KN; Fabian P The directory of P450-containing systems on WorldWide Web	4	3
10121	6	10121 1996 CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY 31(2):101-126 Okita RT; Okita JR Prostaglandin-metabolizing enzymes during pregnancy: Characterization of NAD(+)-dependent prostaglandin dehydrogenase, carbonyl reductase, and cytochrome P450- dependent prostaglandin omega-hydroxylase	29	1
10122	47	10122 1996 CRITICAL REVIEWS IN PLANT SCIENCES 15(3):235-284 Schuler MA Plant cytochrome P450 monooxygenases	114	35
10123	3	10123 1996 CRITICAL REVIEWS IN TOXICOLOGY 26(2):213-249 Warshawsky D; Talaska G; Xue WL; Schneider J Comparative carcinogenicity, metabolism, mutagenicity, and DNA binding of 7H-dibenzo[c,g]carbazole and dibenz[a,j]acridine	26	3
10124	56	10124 1996 CRITICAL REVIEWS IN TOXICOLOGY 26(5):551-583 Guengerich FP; Gillam EMJ; Shimada T New applications of bacterial systems to problems in toxicology	43	22
10125	4	10125 1996 CURRENT EYE RESEARCH 15(8):852-859 Williams KK; Woods WD; Edelhauser HF Corneal diffusion and metabolism of 12(R)- hydroxyeicosatetraenoic acid (12(R)HETE)	2	0
10126	7	10126 1996 CURRENT GENETICS 30(5):367-380 Rep M; Grivell LA The role of protein degradation in mitochondrial function and biogenesis	44	0
10127	8	10127 1996 CURRENT OPINION IN BIOTECHNOLOGY 7(5):494-499 Weickert MJ; Doherty DH; Best EA; Olins PO Optimization of heterologous protein production in Escherichia coli	32	0
10128	1	10128 1996 CURRENT OPINION IN GENETICS & DEVELOPMENT 6(6):723-730 Eppig JT Comparative maps: Adding pieces to the mammalian jigsaw puzzle	14	0
10129	22	10129 1996 CYTOCHROME P450, PT B 272():3-14 Barnes HJ Maximizing expression of eukaryotic cytochrome P450s in Escherichia coli	33	19
10130	11	10130 1996 CYTOCHROME P450, PT B 272():15-25 Fisher CW; Shet MS; Estabrook RW Construction of plasmids and expression in Escherichia coli of enzymatically active fusion proteins containing the heme-domain of a P450 linked to NADPH-P450 reductase	13	13
10131	16	10131 1996 CYTOCHROME P450, PT B 272():35-44 Guengerich FP; Martin MV; Guo ZY; Chun YJ Purification of functional recombinant P450s from bacteria	30	16
10132	5	10132 1996 CYTOCHROME P450, PT B 272():44-51 Estabrook RW; Faulkner KM; Shet MS; Fisher CW Application of electrochemistry for P450-catalyzed reactions	22	22
10133	9	10133 1996 CYTOCHROME P450, PT B 272():152-163 Kupfer D; Dehal SS Tamoxifen metabolism by microsomal cytochrome P450 and flavin- containing monooxygenase	12	2
10134	3	10134 1996 CYTOCHROME P450, PT B 272():268-274 Halkier BA; Sibbesen O; Moller BL Isolation of plant and recombinant CYP79	2	0
10135	5	10135 1996 CYTOCHROME P450, PT B 272():275-283 Holton TA; Lester DR Cloning of novel cytochrome P450 gene sequences via polymerase chain reaction amplification	10	3
10136	6	10136 1996 CYTOCHROME P450, PT B 272():315-326 GrahamLorence SE; Peterson JA Structural alignments of P450s and extrapolations to the unknown	38	17
10137	10	10137 1996 DESIGNING SAFER CHEMICALS 640():116-137 Jones JP Predicting rates of cytochrome-P450-mediated bioactivation and its application to the design of safer chemicals	0	0
10138	3	10138 1996 DIABETES 45(10):1386-1395 Graier WF; Simecek S; Kukovetz WR; Kostner GM High D-glucose-induced changes in endothelial Ca2+/EDRF signaling are due to generation of superoxide anions	89	0
10139	6	10139 1996 DISEASES OF AQUATIC ORGANISMS 25(1-2):39-52 Arnold H; Pluta HJ; Braunbeck T Cytological alterations in the liver of rainbow trout Oncorhynchus mykiss after prolonged exposure to low concentrations of waterborne endosulfan	10	0
10140	10	10140 1996 DRUG AND CHEMICAL TOXICOLOGY 19(1-2):97-107 Ramana KV; Kohli KK Induction of hepatic cytochrome P450 by phenobarbitone in rhesus monkey (Macaca mulatta)	1	1
10141	8	10141 1996 DRUG DISCOVERY TODAY 1(5):209-216 Cashman JR Drug discovery and drug metabolism	13	2
10142	8	10142 1996 DRUG METABOLISM AND DISPOSITION 24(1):23-27 Zhang XJ; Thomas PE Erythromycin as a specific substrate for cytochrome P4503A isozymes and identification of a high-affinity erythromycin N- demethylase in adult female rats	23	5
10143	15	10143 1996 DRUG METABOLISM AND DISPOSITION 24(1):74-80 Poet TS; McQueen CA; Halpert JR Participation of cytochromes P4502B and P4503A in cocaine toxicity in rat hepatocytes	20	4
10144	21	10144 1996 DRUG METABOLISM AND DISPOSITION 24(1):126-136 Rodrigues AD; Kukulka MJ; Roberts EM; Ouellet D; Rodgers TR [O-methyl C-14]naproxen O-demethylase activity in human liver microsomes - Evidence for the involvement of cytochrome P4501A2 and P4502C9/10	33	11
10145	25	10145 1996 DRUG METABOLISM AND DISPOSITION 24(2):164-171 Irshaid Y; Branch RA; Adedoyin A Metabolic interactions of putative cytochrome P4503A substrates with alternative pathways of dapsone metabolism in human liver microsomes	7	3
10146	9	10146 1996 DRUG METABOLISM AND DISPOSITION 24(3):322-328 Zhang QY; Wikoff J; Dunbar D; Kaminsky L Characterization of rat small intestinal cytochrome P450 composition and inducibility	45	12
10147	20	10147 1996 DRUG METABOLISM AND DISPOSITION 24(4):401-407 Sewer MB; Koop DR; Morgan ET Endotoxemia in rats is associated with induction of the P4504A subfamily and suppression of several other forms of cytochrome P450	44	3
10148	4	10148 1996 DRUG METABOLISM AND DISPOSITION 24(4):447-455 Walker DK; Alabaster CT; Congrave GS; Hargreaves MB; Hyland R; Jones BC; Reed LJ; Smith DA Significance of metabolism in the disposition and action of the antidysrhythmic drug, dofetilide - In vitro studies and correlation with in vivo data	15	2
10149	12	10149 1996 DRUG METABOLISM AND DISPOSITION 24(4):462-468 Boucher JL; Delaforge M; Salaun JP; Pinot F; Durst F; Pflieger P; Mioskowski C In vitro hydroxylation and epoxidation of some isomeric lauric acid analogs by rat liver microsomes - Identification of metabolites and effects of clofibrate or phenobarbital pretreatment	4	1
10150	6	10150 1996 DRUG METABOLISM AND DISPOSITION 24(4):502-505 Raftogianis RB; Franklin MR; Galinsky RE Effect of total parenteral nutrition containing lipid calories on hepatic drug metabolism in rats	2	1
10151	8	10151 1996 DRUG METABOLISM AND DISPOSITION 24(5):523-528 Smith BJ; Zupan LA; Hu JK; Diters RW; Gibson GW; Norton JN Characterization of the effects of tebufelone on hepatic cytochromes P450 in the beagle dog	2	0
10152	8	10152 1996 DRUG METABOLISM AND DISPOSITION 24(6):619-627 Panesar SK; Bandiera SM; Abbott FS Comparative effects of carbamazepine and carbamazepine-10,11- epoxide on hepatic cytochromes P450 in the rat	11	3
10153	10	10153 1996 DRUG METABOLISM AND DISPOSITION 24(6):643-648 Nyberg SL; Mann HJ; Hu MY; Payne WD; Hu WS; Cerra FB; Remmel RP Extrahepatic metabolism of 4-methylumbelliferone and lidocaine in the anhepatic rabbit	4	0
10154	16	10154 1996 DRUG METABOLISM AND DISPOSITION 24(6):664-668 Laethem RM; Balazy M; Koop DR Expoxidation of C-18 unsaturated fatty acids by cytochromes P4502C2 and and P4502CAA	9	3
10155	18	10155 1996 DRUG METABOLISM AND DISPOSITION 24(8):884-890 Su T; Sheng JJ; Lipinskas TW; Ding XX Expression of CYP2A genes in rodent and human nasal mucosa	37	17
10156	16	10156 1996 DRUG METABOLISM AND DISPOSITION 24(8):899-905 Huang ZQ; Fasco MJ; Figge HL; Keyomarsi K; Kaminsky LS Expression of cytochromes P450 in human breast tissue and tumors	67	17
10157	13	10157 1996 DRUG METABOLISM AND DISPOSITION 24(9):932-939 Feierman DE; Lasker JM Metabolism of fentanyl, a synthetic opioid analgesic, by human liver microsomes - Role of CYP3A4	19	7
10158	3	10158 1996 DRUG METABOLISM AND DISPOSITION 24(11):1224-1230 Swales NJ; Johnson T; Caldwell J Cryopreservation of rat and mouse hepatocytes .2. Assessment of metabolic capacity using testosterone metabolism	16	2
10159	22	10159 1996 DRUG METABOLISM AND DISPOSITION 24(11):1247-1253 Sharma U; Roberts ES; Hollenberg PF Formation of a metabolic intermediate complex of cytochrome p4502B1 by clorgyline	0	0
10160	19	10160 1996 DRUG METABOLISM AND DISPOSITION 24(11):1254-1262 Yu L; Waxman DJ Role of cytochrome P450 in oxazaphosphorine metabolism - Deactivation via N-dechloroethylation and activation via 4- hydroxylation catalyzed by distinct subsets of rat liver cytochromes P450	28	5
10161	6	10161 1996 DRUG METABOLISM AND DISPOSITION 24(11):1282-1285 Fang XJ; Halpert JR Dithionite-supported hydroxylation of palmitic acid by cytochrome P450BM-3	4	3
10162	9	10162 1996 DRUG METABOLISM AND DISPOSITION 24(12):1314-1319 Schmalix WA; Lang D; Schneider A; Bocker R; Greim H; Doehmer J Stable expression and coexpression of human cytochrome P450 oxidoreductase and cytochrome p450 1A2 in V79 Chinese hamster cells: Sensitivity to quinones and biotransformation of 7- alkoxyresorufins and triazines	10	0
10163	9	10163 1996 DRUG METABOLISM REVIEWS 28(4):591-623 Ekins S Past, present, and future applications of precision-cut liver slices for in vitro xenobiotic metabolism	35	4
10164	2	10164 1996 ELECTRONIC JOURNAL OF THEORETICAL CHEMISTRY 1():45-51 Navajas C; Poso A; Gynther J CoMFA of flavonoids with antimutagenic activity against 2- amino-3-methylimidazo[4,5-f]quinoline (IQ)	1	0
10165	6	10165 1996 ENDOCRINE 4(2):151-157 McGee EA; Nguyen A; Mason JI; Rainey WE; Carr BR Protein kinase A and protein kinase C differentially regulate steroidogenesis in human ovarian thecal tumor cells	1	0
10166	9	10166 1996 ENDOCRINE JOURNAL 43(1):1-14 Ohtaki S; Nakagawa H; Nakamura M; Kotani T Thyroid peroxidase: Experimental and clinical integration	11	0
10167	7	10167 1996 ENDOCRINE RESEARCH 22(4):665-671 Estabrook RW; Shet MS; Faulkner K; Fisher CW The use of electrochemistry for the synthesis of 17 alpha- hydroxyprogesterone by a fusion protein containing P450c17	9	9
10168	28	10168 1996 ENDOCRINE REVIEWS 17(3):221-244 Stocco DM; Clark BJ Regulation of the acute production of steroids in steroidogenic cells	316	15
10169	21	10169 1996 ENDOCRINE-RELATED CANCER 3(1):25-39 Barrie SE; Jarman M Inhibitors of cytochrome P450(17 alpha) (17 alpha- hydroxylase/C17,20 lyase)	8	2
10170	7	10170 1996 ENDOCRINOLOGY 137(6):2406-2414 Yagci A; Oertle M; Seiler H; Schmid D; Campofranco C; Muller J Potassium induces multiple steroidogenic enzymes in cultured rat zona glomerulosa cells	7	1
10171	6	10171 1996 ENDOCRINOLOGY 137(10):4331-4338 Yagci A; Muller J Induction of steroidogenic enzymes by potassium in cultured rat zona glomerulosa cells depends on calcium influx and intact protein synthesis	6	0
10172	11	10172 1996 ENVIRONMENTAL HEALTH PERSPECTIVES 104():97-106 Hodgson E; Levi PE Pesticides: An important but underused model for the environmental health sciences	27	0
10173	10	10173 1996 ENVIRONMENTAL HEALTH PERSPECTIVES 104(5):536-543 Heinonen JT; Sidhu JS; Reilly MT; Farin FM; Omiecinski CJ; Eaton DL; Kavanagh TJ Assessment of regional cytochrome P450 activities in rat liver slices using resorufin substrates and fluorescence confocal laser cytometry	13	2
10174	20	10174 1996 ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 1(1):1-11 Jacob J; Raab G; Soballa V; Schmalix WA; Grimmer G; Greim H; Doehmer J; Seidel A Cytochrome P450-mediated activation of phenanthrene in genetically engineered V79 Chinese hamster cells	40	2
10175	5	10175 1996 ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 2(4):331-337 Tsuji R; Isobe N; Kurita Y; Hanai K; Yabusaki Y; Kawasaki H Species difference in the inhibition of pentobarbital metabolism by empenthrin	1	1
10176	3	10176 1996 EUROPEAN JOURNAL OF BIOCHEMISTRY 235(3):660-669 Jung C; Ristau O; Schulze H; Sligar SG The CO stretching mode infrared spectrum of substrate-free cytochrome P-450(cam)-CO - The effect of solvent conditions, temperature, and pressure	20	8
10177	17	10177 1996 EUROPEAN JOURNAL OF BIOCHEMISTRY 238(2):476-483 Vieira I; Sonnier M; Cresteil T Developmental expression of CYP2E1 in the human liver - Hypermethylation control of gene expression during the neonatal period	36	11
10178	18	10178 1996 EUROPEAN JOURNAL OF BIOCHEMISTRY 238(2):495-504 Dumas B; Cauet G; Lacour T; Degryse E; Laruelle L; Ledoux C; Spagnoli R; Achstetter T 11 beta-hydroxylase activity in recombinant yeast mitochondria - In vivo conversion of 11-deoxycortisol to hydrocortisone	12	6
10179	19	10179 1996 EUROPEAN JOURNAL OF BIOCHEMISTRY 239(2):403-409 Munro AW; Daff S; Coggins JR; Lindsay JG; Chapman SK Probing electron transfer in flavocytochrome P-450 BM3 and its component domains	25	14
10180	7	10180 1996 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 49(4):305-308 Bonnabry P; Leemann T; Dayer P Role of human liver microsomal CYP2C9 in the biotransformation of lornoxicam	15	1
10181	5	10181 1996 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 49(6):491-495 Rizzo N; Padoin C; Palombo S; Scherrmann JM; Girre C Omeprazole and lansoprazole are not inducers of cytochrome P4501A2 under conventional therapeutic conditions	12	2
10182	6	10182 1996 EUROPEAN JOURNAL OF HAEMATOLOGY 57():89-92 Beaune PH; Lecoeur S; Bourdi M; Gauffre A; Belloc C; Dansette P; Mansuy D Anti-cytochrome P450 autoantibodies in drug-induced disease	2	1
10183	1	10183 1996 EUROPEAN NEUROLOGY 36(5):260-267 Walker UA; Collins S; Byrne E Respiratory chain encephalomyopathies: A diagnostic classification	20	2
10184	3	10184 1996 EUROPEAN RESPIRATORY JOURNAL 9(10):2077-2086 Corrigan CJ; Bungre JK; Assoufi B; Cooper AE; Seddon H; Kay AB Glucocorticoid resistant asthma: T-lymphocyte steroid metabolism and sensitivity to glucocorticoids and immunosuppressive agents	11	0
10185	5	10185 1996 EXPERIENTIA 52(8):827-830 Kalapos MP; Riba P; Garzo T; Mandl J Glucose formation from methylglyoxal in hepatocytes from streptozotocin-induced diabetic mice: The effect of insulin	3	0
10186	9	10186 1996 EXPERIENTIA 52(9):851-855 VandenBroek PJA; Barroso M; Lechner MC Critical amino-terminal segments in insertion of rat liver cytochrome P450 3A1 into the endoplasmic reticulum membrane	3	1
10187	5	10187 1996 EXPERIMENTAL AND MOLECULAR MEDICINE 28(4):167-172 Hong YS; Park HY; Park SS Diallyl sulfide down-regulates polycyclic aromatic hydrocarbon- induced cytochrome P450 1A1 in mouse liver and lung	0	0
10188	3	10188 1996 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 48(4):265-268 Giermaziak H; Tosik D Morphometric studies of the hepatocyte mitochondria and endoplasmic reticulum after acute ethylene glycol poisoning	3	0
10189	11	10189 1996 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 48(5):433-438 Muller D; Glockner R; Post M Monooxygenation, cytochrome P4501A1 and P4501A1-mRNA in rat liver slices exposed to beta-naphthoflavone and dexamethasone in vitro	15	4
10190	4	10190 1996 EXPERIMENTAL EYE RESEARCH 62(4):449-452 McAvoy M; Singh AK; Shichi H In situ hybridization of Cyp1a1, Cyp1a2 and Ah receptor mRNAs expressed in murine ocular tissues	2	1
10191	11	10191 1996 FASEB JOURNAL 10(2):202-204 Estabrook RW The remarkable P4150s: A historical overview of these versatile hemeprotein catalysts	23	23
10192	3	10192 1996 FASEB JOURNAL 10(2):205-205 Masters BSS Introduction: Cytochrome P450	2	1
10193	23	10193 1996 FASEB JOURNAL 10(2):206-214 GrahamLorence S; Peterson JA P450s: Structural similarities and functional differences	56	28
10194	15	10194 1996 FASEB JOURNAL 10(7):683-689 Negishi M; Uno T; Darden TA; Sueyoshi T; Pedersen LG Structural flexibility and functional versatility of mammalian P450 enzymes	42	22
10195	23	10195 1996 FASEB JOURNAL 10(10):1112-1117 Gonzalez FJ; Lee YH Cytochromes P450 .6. Constitutive expression of hepatic cytochrome P450 genes	49	23
10196	11	10196 1996 FASEB JOURNAL 10(11):1241-1248 Johnson EF; Palmer CNA; Griffin KJ; Hsu MH Cytochromes P450 .7. Role of the peroxisome proliferator- activated receptor in cytochrome P450 4A gene regulation	70	20
10197	4	10197 1996 FASEB JOURNAL 10(13):1455-1455 Waterman MR Introduction: Transcription and regulation of activities of cytochromes P450 metabolizing endogenous substrates	1	1
10198	21	10198 1996 FASEB JOURNAL 10(13):1456-1463 Makita K; Falck JR; Capdevila JH Cytochrome P450, the arachidonic acid cascade, and hypertension: New vistas for an old enzyme system	80	35
10199	17	10199 1996 FEBS LETTERS 397(2-3):210-214 Blake JAR; Pritchard M; Ding SH; Smith GCM; Burchell B; Wolf CR; Friedberg T Coexpression of a human P450 (CYP3A4) and P450 reductase generates a highly functional monooxygenase system in Escherichia coli	45	27
10200	5	10200 1996 FEMS MICROBIOLOGY LETTERS 139(2-3):203-207 Hargreaves JA; Keon JPR Isolation of an Ustilago maydis ERG11 gene and its expression in a mutant deficient in sterol 14 alpha-demethylase activity	13	5

#	Cited nodes	Nodes / Authors	GCS	LCS
10201	21	10201 1996 FISH PHYSIOLOGY AND BIOCHEMISTRY 15(4):323-332 Celander M; Buhler DR; Forlin L; Goksoyr A; Miranda CL; Woodin BR; Stegeman JJ Immunochemical relationships of cytochrome P4503A-like proteins in teleost fish	29	11
10202	3	10202 1996 FISHERIES SCIENCE 62(1):114-121 Iijima N; Hada T; Kayama M Production of monohydroxy derivatives from highly unsaturated fatty acids in the gills of red sea bream Pagrus major	2	1
10203	6	10203 1996 FOOD AND CHEMICAL TOXICOLOGY 34(7):595-601 Sun B; Fukuhara M; Kinoshita T; Kimura M; Ushio F Differential induction of isozymes of drug-metabolizing enzymes by butylated hydroxytoluene in mice and Chinese hamsters	5	0
10204	14	10204 1996 FUNDAMENTAL AND APPLIED TOXICOLOGY 34(2):165-175 Miller MS; Juchau MR; Guengerich FP; Nebert DW; Raucy JL Drug metabolic enzymes in developmental toxicology	24	4
10205	5	10205 1996 GENE 169(1):105-109 Skaggs BA; Alexander JF; Pierson CA; Schweitzer KS; Chun KT; Koegel C; Barbuch R; Bard M Cloning and characterization of the Saccharomyces cerevisiae C- 22 sterol desaturase gene, encoding a second cytochrome P-450 involved in ergosterol biosynthesis	27	3
10206	5	10206 1996 GENE 172(2):309-312 Brown LJ; Stoffel M; Moran SM; Fernald AA; Lehn DA; LeBeau MM; MacDonald MJ Structural organization and mapping of the human mitochondrial glycerol phosphate dehydrogenase-encoding gene and pseudogene	8	3
10207	7	10207 1996 GENE 180(1-2):165-171 Maitra S; Dombrowski SM; Waters LC; Ganguly R Three second chromosome-linked clustered Cyp6 genes show differential constitutive and barbital-induced expression in DDT-resistant and susceptible strains of Drosophila melanogaster	25	9
10208	19	10208 1996 GENERAL AND COMPARATIVE ENDOCRINOLOGY 102(2):173-182 Trant JM Heterologous expression of the spiny dogfish shark (Squalus acanthias) cytochrome P450c17 (17 alpha-hydroxylase) in Escherichia coli	5	3
10209	6	10209 1996 GENOMICS 38(1):96-99 Koike G; VanVooren P; Shiozawa M; Galli J; Li LS; Glaser A; Balasubramanyam A; Brown LJ; Luthman H; Szpirer C; MacDonald MJ; Jacob HJ Genetic mapping and chromosome localization of the rat mitochondrial glycerol-3-phosphate dehydrogenase gene, a candidate for non-insulin-dependent diabetes mellitus	10	1
10210	19	10210 1996 GENOMICS 38(3):371-381 Rozman D; Stromstedt M; Tsui LC; Scherer SW; Waterman MR Structure and mapping of the human lanosterol 14 alpha- demethylase gene (CYP51) encoding the cytochrome P450 involved in cholesterol biosynthesis; Comparison of exon/intron organization with other mammalian and fungal CYP genes	33	12
10211	5	10211 1996 GERONTOLOGY 42():67-77 Wakino S; Meguro M; Suzuki H; Saruta T; Ogishima T; Ishimura Y; Shinki T; Suda T Evidence for 54-kD protein in chicken kidney as a cytochrome P450 with a high molecular activity of 25-hydroxyvitamin D-3 1 alpha-hydroxylase	4	2
10212	5	10212 1996 GYNECOLOGIC AND OBSTETRIC INVESTIGATION 41(3):147-172 Lieberman S Are estradiol-producing cells incompletely endowed? A chronicle of the emergence of certitude from conjecture	3	1
10213	2	10213 1996 HEPATOLOGY 23(1):80-86 Frost L; Mahoney J; Field J; Farrell GC Impaired bile flow and disordered hepatic calcium homeostasis are early features of halothane-induced liver injury in guinea pigs	3	1
10214	15	10214 1996 HEPATOLOGY 23(3):515-523 Pellinen P; Stenback F; Kojo A; Honkakoski P; Gelboin HV; Pasanen M Regenerative changes in hepatic morphology and enhanced expression of CYP2B10 and CYP3A during daily administration of cocaine	15	4
10215	2	10215 1996 HEPATOLOGY 24(3):677-684 Johnston DE; Kroening C Stimulation of prostaglandin synthesis in cultured liver cells by CCl4	11	1
10216	9	10216 1996 HUMAN & EXPERIMENTAL TOXICOLOGY 15(1):45-50 Kraul H; Pasanen M; Sigusch H; Stenback F; Park SS; Gelboin HV; Pelkonen O Immunohistochemical properties of dipyrone-induced cytochromes P450 in rats	1	0
10217	30	10217 1996 HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL 11(2):97-114 Glue P; Banfield C Psychiatry, psychopharmacology and P-450s	39	11
10218	6	10218 1996 IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 18(2):237-245 Hornstein EH; Vassilopoulos D; Thomas DE; Friedman FK; Tsokos GC Modulation of human T-lymphocyte plasma membrane Ca+2 permeability by imidazole antimycotics.	3	0
10219	7	10219 1996 IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 18(4):571-586 Walter R; Siegmund W; Scheuch E Effects of interferon-gamma and streptolysin O on hepatic procainamide N-acetyltransferase and various microsomal cytochrome P450-dependent monooxygenases in rats	6	0
10220	5	10220 1996 INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 26(3):267-276 Reed JR; Hernandez P; Blomquist GJ; Feyereisen R; Reitz RC Hydrocarbon biosynthesis in the house fly, Musca domestica: Substrate specificity and cofactor requirement of P450hyd	4	0
10221	11	10221 1996 INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 26(7):697-703 Brun A; Cuany A; LeMouel T; Berge J; Amichot M Inducibility of the Drosophila melanogaster cytochrome P450 gene, CYP6A2, by phenobarbital in insecticide susceptible or resistant strains	22	10
10222	6	10222 1996 INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY 11():15-27 Puozzo C; Leonard BE Pharmacokinetics of milnacipran in comparison with other antidepressants	22	0
10223	23	10223 1996 INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY 11():31-61 Lane RM Pharmacokinetic drug interaction potential of selective serotonin reuptake inhibitors	53	8
10224	10	10224 1996 JAPANESE JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 42(6):468-478 Kobayashi Y; Yamamoto T; Okui E; Kotani E; Yoshida T; Kuroiwa Y Regio-related differential induction of hepatic microsomal heme oxygenase and cytochrome P450 by substituted imidazole and pyridine compounds in rats	5	0
10225	2	10225 1996 JOURNAL OF APPLIED TOXICOLOGY 16(2):121-128 Chu I; Villeneuve DC; Yagminas A; Lecavalier P; Poon R; Feeley M; Kennedy SW; Seegal RF; Hakansson H; Ahlborg UG; Valli VE; Bergman A Toxicity of 2,2',4,4',5,5'-hexachlorobiphenyl in rats: Effects following 90-day oral exposure	12	2
10226	7	10226 1996 JOURNAL OF APPLIED TOXICOLOGY 16(4):331-337 Rahman M; Fujii K; Kawamoto M; Yuge O Contrasting effect of isoflurane on drug metabolism: Decreased type I and increased type II substrate metabolism in guinea pig liver microsomes	2	0
10227	5	10227 1996 JOURNAL OF AUTOIMMUNITY 9(4):529-536 Fan JL; Patibandla SA; Kimura S; Rao TN; Desai RK; Seetharamaiah GS; Kurosky A; Prabhakar BS Purification and characterization of a recombinant human thyroid peroxidase expressed in insect cells	8	0
10228	2	10228 1996 JOURNAL OF BACTERIOLOGY 178(1):204-208 Mylona PV; Premakumar R; Pau RN; Bishop PE Characteristics of orf1 and orf2 in the anfHDGK genomic region encoding nitrogenase 3 of Azotobacter vinelandii	2	0
10229	6	10229 1996 JOURNAL OF BASIC MICROBIOLOGY 36(2):121-147 Balakrishnan K; Pandey A The panorama of cyclosporin research	7	0
10230	16	10230 1996 JOURNAL OF BIOCHEMISTRY 119(2):340-345 Hiratsuka M; Matsuura T; Watanabe E; Sato M; Suzuki Y Sex and strain differences in constitutive expression of fatty acid omega-hydroxylase (CYP4A-related proteins) in mice	3	2
10231	13	10231 1996 JOURNAL OF BIOCHEMISTRY 119(3):435-440 Nakayama N; Takemae A; Shoun H Cytochrome P450foxy, a catalytically self-sufficient fatty acid hydroxylase of the fungus Fusarium oxysporum	15	12
10232	11	10232 1996 JOURNAL OF BIOCHEMISTRY 119(5):926-933 Aoyama Y; Noshiro M; Gotoh O; Imaoka S; Funae Y; Kurosawa N; Horiuchi T; Yoshida Y Sterol 14-demethylase P450 (P45014DM*) is one of the most ancient and conserved P450 species	47	16
10233	5	10233 1996 JOURNAL OF BIOCHEMISTRY 120(6):1082-1087 Nakahara K; Shoun H N-terminal processing and amino acid sequence of two isoforms of nitric oxide reductase cytochrome P450nor from Fusarium oxysporum	14	3
10234	19	10234 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(6):3306-3310 Hsu LC; Hsu NC; Guzova JA; Guzov VM; Chang SF; Chung BC The common I172N mutation causes conformational change of cytochrome P450c21 revealed by systematic mutation, kinetic, and structural studies	13	5
10235	44	10235 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(7):3460-3468 Wu S; Moomaw CR; Tomer KB; Falck JR; Zeldin DC Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart	75	46
10236	9	10236 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(7):3507-3516 Street JM; Evans JE; Natowicz MR Glucuronic acid-conjugated dihydroxy fatty acids in the urine of patients with generalized peroxisomal disorders	13	1
10237	18	10237 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(14):8028-8033 Bottner B; Schrauber H; Bernhardt R Engineering a mineralocorticoid- to a glucocorticoid- synthesizing cytochrome P450	14	8
10238	3	10238 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(14):8243-8249 Nomura M; Nawata H; Morohashi K Autoregulatory loop in the regulation of the mammalian ftz-f1 gene	23	1
10239	18	10239 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(15):8570-8574 Nakano R; Sato H; Watanabe A; Ito O; Shimizu T Conserved Glu(318) at the cytochrome P450 1A2 distal site is crucial in the nitric oxide complex stability	22	6
10240	14	10240 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(20):12063-12067 Lee SST; Buters JTM; Pineau T; FernandezSalguero P; Gonzalez FJ Role of CYP2E1 in the hepatotoxicity of acetaminophen	108	16
10241	27	10241 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(21):12496-12501 Ibeanu GC; Ghanayem BI; Linko P; Li LP; Pedersen LG; Goldstein JA Identification of residues 99, 220, and 221 of human cytochrome P450 2C19 as key determinants of omeprazole hydroxylase activity	41	19
10242	19	10242 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(24):14001-14009 VanRollins M; Kaduce TL; Fang X; Knapp HR; Spector AA Arachidonic acid diols produced by cytochrome P-450 monooxygenases are incorporated into phospholipids of vascular endothelial cells	29	12
10243	4	10243 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(24):14112-14118 Su C; Oliw EH Purification and characterization of linoleate 8-dioxygenase from the fungus Gaeumannomyces graminis as a novel hemoprotein	12	1
10244	10	10244 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(24):14631-14635 Chen PF; Tsai AL; Berka V; Wu KK Endothelial nitric-oxide synthase - Evidence for bidomain structure and successful reconstitution of catalytic activity from two separate domains generated by a baculovirus expression system	65	2
10245	3	10245 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(25):14734-14739 Vidakovic MS; Fraczkiewicz G; Germanas JP Expression and spectroscopic characterization of the hydrogenosomal [2Fe-2S] ferredoxin from the protozoan Trichomonas vaginalis	11	0
10246	7	10246 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(33):19970-19975 Wang LH; MatijevicAleksic N; Hsu PW; Ruan KH; Wu KK; Kulmacz RJ Identification of thromboxane A(2), synthase active site residues by molecular modeling-guided site-directed mutagenesis	15	4
10247	22	10247 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(37):22462-22469 Sibbesen O; DeVoss JJ; deMontellano PRO Putidaredoxin reductase-putidaredoxin-cytochrome P450(cam) triple fusion protein - Construction of a self-sufficient Escherichia coli catalytic system	25	19
10248	21	10248 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(37):22663-22671 Capdevila JH; Wei SZ; Helvig C; Falck JR; Belosludtsev Y; Truan G; GrahamLorence SE; Peterson JA The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3	45	26
10249	2	10249 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(38):23105-23110 Ayala A; Parrado J; Bougria M; Machado A Effect of oxidative stress, produced by cumene hydroperoxide, on the various steps of protein synthesis - Modifications of elongation factor-2	15	0
10250	13	10250 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(41):25269-25276 Cairns W; Smith CAD; McLaren AW; Wolf CR Characterization of the human cytochrome P4502D6 promoter - A potential role for antagonistic interactions between members of the nuclear receptor family	24	10
10251	17	10251 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(42):26209-26213 Sakaki T; Kominami S; Hayashi K; AkiyoshiShibata M; Yabusaki Y Molecular engineering study on electron transfer from NADPH- P450 reductase to rat mitochondrial P450c27 in yeast microsomes	14	8
10252	24	10252 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(43):26637-26645 Guzov VM; Houston HL; Murataliev MB; Walker FA; Feyereisen R Molecular cloning, overexpression in Escherichia coli, structural and functional characterization of house fly cytochrome b(5)	20	5
10253	36	10253 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(44):27438-27444 Yamazaki H; Johnson WW; Ueng YF; Shimada T; Guengerich FP Lack of electron transfer from cytochrome b(5) in stimulation of catalytic activities of cytochrome P450 3A4 - Characterization of a reconstituted cytochrome P450 3A4 NADPH- cytochrome P450 reductase system and studies with apo- cytochrome b(5)	63	43
10254	9	10254 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(45):28176-28180 Kawashima H; Sequeira DJ; Nelson DR; Strobel HW Genomic cloning and protein expression of a novel rat brain cytochrome P-450 CYP2D18 catalyzing imipramine N-demethylation	29	12
10255	8	10255 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(45):28607-28611 Chen CD; Kemper B Different structural requirements at specific proline residue positions in the conserved proline-rich region of cytochrome P450 2C2	15	9
10256	3	10256 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(47):29922-29927 White JA; Guo YD; Baetz K; BeckettJones B; Bonasoro J; Hsu KE; Dilworth FJ; Jones G; Petkovich M Identification of the retinoic acid-inducible all-trans- retinoic acid 4-hydroxylase	118	8
10257	19	10257 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(47):29978-29987 Waxman DJ; Zhao SP; Choi HK Interaction of a novel sex-dependent, growth hormone-regulated liver nuclear factor with CYP2C12 promoter	29	4
10258	19	10258 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(49):31312-31316 Yun CH; Song M; Ahn T; Kim H Conformational change of cytochrome p450 1A2 induced by sodium chloride	20	9
10259	9	10259 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(50):32269-32275 Eggertsen G; Olin M; Andersson U; Ishida H; Kubota S; Hellman U; KyuIchiro O; Bjorkhem I Molecular cloning and expression of rabbit sterol 12 alpha- hydroxylase	27	9
10260	11	10260 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(51):32944-32950 Kahn RA; Bak S; Olsen CE; Svendsen I; Moller BL Isolation and reconstitution of the heme-thiolate protein obtusifoliol 14 alpha-demethylase from Sorghum bicolor (L.) Moench	17	6
10261	11	10261 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(51):33054-33059 Gilday D; Gannon M; Yutzey K; Bader D; Rifkind AB Molecular cloning and expression of two novel avian cytochrome p450 1A enzymes induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin	48	21
10262	7	10262 1996 JOURNAL OF BIOMOLECULAR NMR 8(2):171-183 Sarma S; DiGate RJ; Banville DL; Guiles RD H-1, C-13 and N-15 NMR assignments and secondary structure of the paramagnetic form of rat cytochrome b(5)	13	4
10263	3	10263 1996 JOURNAL OF CATALYSIS 164(2):341-346 Parton RF; Neys PE; Jacobs PA; Sosa RC; Rouxhet PG Iron-phthalocyanine immobilized on activated carbon black: A selective catalyst for alkane oxidation	17	0
10264	2	10264 1996 JOURNAL OF CELLULAR PHYSIOLOGY 169(2):309-319 Hong JT; Glauert HP Comitogenicity of eicosanoids and the peroxisome proliferator ciprofibrate in cultured rat hepatocytes	14	2
10265	12	10265 1996 JOURNAL OF CHROMATOGRAPHY A 730(1-2):91-98 Yamane M; Abe A; Shimizu S; Nakajima M Subcellular localization of docosahexaenoic acid and arachidonic acid omega-hydroxylation activity in the brain, liver and colonic adenocarcinoma	3	2
10266	13	10266 1996 JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS 678(1):93-103 Engel G; Hofmann U; Kroemer HK Prediction of CYP2DG-mediated polymorphic drug metabolism (sparteine type) based on in vitro investigations	3	1
10267	6	10267 1996 JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS 678(1):105-111 Jones DR; Gorski JC; Hamman MA; Hall SD Quantification of dextromethorphan and metabolites: A dual phenotypic marker for cytochrome P450 3A4/5 and 2D6 activity	24	3
10268	18	10268 1996 JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS 678(2):339-343 Yamane M; Abe A High-performance liquid chromatography-thermospray mass spectrometry of 5,6-dihydroxyeicosatrienoate-1,5-lactone from tissue homogenates	3	2
10269	52	10269 1996 JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS 684(1-2):107-131 Roos PH Chromatographic separation and behavior of microsomal cytochrome P450 and cytochrome b(5)	3	1
10270	17	10270 1996 JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS 684(1-2):133-145 Jansen EHJM; Laan CA; deFluiter P Advances in sample preparation, electrophoretic separation and detection methods for rat cytochrome P450 enzymes	0	0
10271	4	10271 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(1):257-263 Rainey WE; Sawetawan C; McCarthy JL; McGee EA; Bird LM; Word RA; Carr BR Human ovarian tumor cells: A potential model for thecal cell steroidogenesis	5	1
10272	14	10272 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(1):264-268 Laflamme N; Leblanc JF; Mailloux J; Faure N; Labrie F; Simard J Mutation R96W in cytochrome P450c17 gene causes combined 17 alpha-hydroxylase/17-20-lyase deficiency in two French Canadian patients	18	4
10273	13	10273 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(1):321-326 Fardella CE; Hum DW; Rodriguez H; Zhang GR; Barry FL; Ilicki A; Bloch CA; Miller WL Gene conversion in the CYP11B2 gene encoding P450c11AS is associated with, but does not cause, the syndrome of corticosterone methyloxidase II deficiency	26	3
10274	5	10274 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(3):881-886 Moghetti P; Castello R; Negri C; Tosi F; Spiazzi GG; Brun E; Balducci R; Toscano V; Muggeo M Insulin infusion amplifies 17 alpha-hydroxycorticosteroid intermediates response to adrenocorticotropin in hyperandrogenic women: Apparent relative impairment of 17,20- lyase activity	67	3
10275	8	10275 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(6):2069-2075 Han IS; Choi JH Highly specific cytochrome P450-like enzymes for all-trans- retinoic acid in T47D human breast cancer cells	20	1
10276	7	10276 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(6):2389-2393 Skinner CA; Rumsby G; Honour JW Single strand conformation polymorphism (SSCP) analysis for the detection of mutations in the CYP11B1 gene	12	3
10277	2	10277 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(7):2746-2749 Slominski A; Ermak G; Mihm M ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin.	52	2
10278	11	10278 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(11):3843-3849 Agarwal VR; Bulun SE; Leitch M; Rohrich R; Simpson ER Use of alternative promoters to express the aromatase cytochrome P450 (CYP19) gene in breast adipose tissues of cancer-free and breast cancer patients	61	8
10279	3	10279 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(11):4122-4128 Kiriakidou M; McAllister JM; Sugawara T; Strauss JF Expression of steroidogenic acute regulatory protein (StAR) in the human ovary	56	2
10280	1	10280 1996 JOURNAL OF CLINICAL NEUROSCIENCE 3(4):386-389 Bower S; Nicol S; Kirkland G; Byrne E Exercise intolerance in Kearns-Sayre syndrome	0	0
10281	9	10281 1996 JOURNAL OF CLINICAL PHARMACOLOGY 36(12):1154-1160 Goldberg MJ; Ring B; DeSante K; Cerimele B; Hatcher B; Sides G; Wrighton S Effect of dirithromycin on human CYP3A in vitro and on pharmacokinetics and pharmacodynamics of terfenadine in vivo	7	0
10282	9	10282 1996 JOURNAL OF CLINICAL PSYCHIATRY 57():17-25 Ereshefsky L; Riesenman C; Lam YWF Serotonin selective reuptake inhibitor drug interactions and the cytochrome P450 system	28	3
10283	15	10283 1996 JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 16(3):S37-S50 Ereshefsky L Drug-drug interactions involving antidepressants: Focus on venlafaxine	47	2
10284	2	10284 1996 JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 16(2):101-103 Flockhart DA Drug interactions, cardiac toxicity, and terfenadine: From bench to clinic?	15	0
10285	9	10285 1996 JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 16(2):104-112 vonMoltke LL; Greenblatt DJ; Duan SX; Harmatz JS; Wright CE; Shader RI Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: Relation to pharmacokinetic interactions in vivo	60	14
10286	3	10286 1996 JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 16(3):197-201 Shader RI; vonMoltke LL; Schmider J; Harmatz JS; Greenblat DJ The clinician and drug interactions - An update	42	6
10287	20	10287 1996 JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 16(4):267-272 Schmider J; Greenblatt DJ; vonMoltke LL; Shader RI Relationship of in vitro data on drug metabolism to in vivo pharmacokinetics and drug interactions: Implications for diazepam disposition in humans	33	6
10288	35	10288 1996 JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 16(4):273-285 Harvey AT; Preskorn SH Cytochrome p450 enzymes: Interpretation of their interactions with selective serotonin reuptake inhibitors .1.	57	12
10289	9	10289 1996 JOURNAL OF COMPARATIVE NEUROLOGY 366(2):244-258 Norris PJ; Hardwick JP; Emson PC Regional distribution of cytochrome P450 2D1 in the rat central nervous system	21	3
10290	5	10290 1996 JOURNAL OF ENDOCRINOLOGY 148(2):213-221 Sawetawan C; Carr BR; McGee E; Bird IM; Hong TL; Rainey WE Inhibin and activin differentially regulate androgen production and 17 alpha-hydroxylase expression in human ovarian thecal- like tumor cells	13	4
10291	16	10291 1996 JOURNAL OF ENDOCRINOLOGY 150():S51-S57 Simpson ER; Bulun SE; Nichols JE; Zhao Y Estrogen biosynthesis in adipose tissue: Regulation by paracrine and autocrine mechanisms	10	0
10292	29	10292 1996 JOURNAL OF ENDOCRINOLOGY 150():S129-S147 Waxman DJ Role of metabolism in the activation of dehydroepiandrosterone as a peroxisome proliferator	29	8
10293	33	10293 1996 JOURNAL OF FOOD AND DRUG ANALYSIS 4(1):13-23 Ueng TH; Kang JJ; Chao IC; Chen YC Cytochrome P450: Enzyme regulation and toxicological significance	0	0
10294	6	10294 1996 JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 11(6):594-601 Farrell GC; Frost L; Tapner M; Field J; Weltman M; Mahoney J Halothane-induced liver injury in guinea-pigs: Importance of cytochrome P450 enzyme activity and hepatic blood flow	1	0
10295	1	10295 1996 JOURNAL OF MEDICINAL CHEMISTRY 39(7):1509-1513 Flaherty PT; Greenwood TD; Manheim AL; Wolfe JF Synthesis and evaluation of N- (phenylacetyl)trifluoromethanesulfonamides as anticonvulsant agents	6	0
10296	1	10296 1996 JOURNAL OF MOLECULAR EVOLUTION 42(6):631-640 Hastings KEM Strong evolutionary conservation of broadly expressed protein isoforms in the troponin I gene family and other vertebrate gene families	24	0
10297	2	10297 1996 JOURNAL OF NEUROCHEMISTRY 66(5):2057-2066 Tretter L; AdamVizi V Early events in free radical-mediated damage of isolated nerve terminals: Effects of peroxides on membrane potential and intracellular Na+ and Ca+ concentrations	30	0
10298	6	10298 1996 JOURNAL OF NUTRITION 126(2):403-409 NugonBaudon L; Roland N; Flinois JP; Beaune P Hepatic cytochrome p450 and UDP-glucuronosyl transferase are affected by five sources of dietary fiber in germ-free rats	3	0
10299	10	10299 1996 JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS 12(4):527-539 Gaynes BI; Fiscella RG Biotransformation in review: Applications in ocular disease and drug design	1	0
10300	7	10300 1996 JOURNAL OF ORGANIC CHEMISTRY 61(3):838-841 Yeola SN; Saleh SA; Brash AR; Prakash C; Taber DF; Blair IA Synthesis of 10(S)-hydroxyeicosatetraenoic acid: A novel cytochrome P-450 metabolite of arachidonic acid	7	1

#	Cited nodes	Nodes / Authors	GCS	LCS
10301	4	10301 1996 JOURNAL OF PAEDIATRICS AND CHILD HEALTH 32(5):433-438 Burren CP; Montalto J; Yong ABW; Batch JA CYP11 beta 1 (11-beta-hydroxylase) deficiency in congenital adrenal hyperplasia	0	0
10302	11	10302 1996 JOURNAL OF PESTICIDE SCIENCE 21(1):57-59 Scott JG; Roberts MA Phenobarbital and 3-methylcholanthrene inducible cytochromes P450 are not responsible for metabolism of deltamethrin in rat liver microsomes	0	0
10303	10	10303 1996 JOURNAL OF PESTICIDE SCIENCE 21(2):241-245 Scott JG Cytochrome P450 monooxygenase-mediated resistance to insecticides	8	4
10304	1	10304 1996 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 14(12):1675-1680 Xu A; Linderholm K; Peng L; Hulse J Development and validation of an LC-MS-MS method for the determination of terfenadine in human plasma	10	1
10305	5	10305 1996 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS 24(5):449-459 Meyer UA Overview of enzymes of drug metabolism	33	4
10306	7	10306 1996 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS 24(5):461-473 Wrighton SA; VandenBranden M; Ring BJ The human drug metabolizing cytochromes P450	42	7
10307	11	10307 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 276(1):21-29 ThorntonManning J; Appleton ML; Gonzalez FJ; Yost GS Metabolism of 3-methylindole by vaccinia-expressed P450 enzymes: Correlation of 3-methyleneindolenine formation and protein-binding	36	5
10308	10	10308 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 276(1):238-245 Sidhu JS; Omiecinski CJ Forskolin-mediated induction of CYP3A1 mRNA expression in primary rat hepatocytes is independent of elevated intracellular cyclic AMP	15	5
10309	10	10309 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 276(1):258-264 Kraner JC; Morgan ET; Poet TS; Born SL; Burnett VL; Halpert JR Suppression of rat hepatic microsomal cytochromes P450 by cyclophosphamide is correlated with plasma thyroid hormone levels and displays differential strain sensitivity	6	2
10310	12	10310 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 276(2):370-379 vonMoltke LL; Greenblatt DJ; Harmatz JS; Duan SX; Harrel LM; CotreauBibbo MM; Pritchard GA; Wright CE; Shader RI Triazolam biotransformation by human liver microsomes in vitro: Effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole	126	25
10311	4	10311 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 276(2):602-608 Raftogianis RB; Franklin MR; Galinsky RE Effect of lipid-free total parenteral nutrition on hepatic drug conjugation in rats	3	2
10312	13	10312 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 277(1):292-298 Shelnutt SR; Badger TM; Owens SM Phencyclidine metabolite irreversible binding in the rat: Gonadal steroid regulation and CYP2C11	8	3
10313	24	10313 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 277(1):321-332 Bourrie M; Meunier V; Berger Y; Fabre G Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes	153	33
10314	14	10314 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 277(1):423-431 Kumar GN; Rodrigues AD; Buko AM; Denissen JF Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes	134	14
10315	19	10315 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 277(2):768-774 Nunoya KI; Yokoi T; Kimura K; Kodama T; Funayama M; Inoue K; Nagashima K; Funae Y; Shimada N; Green C; Kamataki T (+)-cis-3,5-dimethyl-2-(3-pyridyl) thiazolidin-4-one hydrochloride (SM-12502) as a novel substrate for cytochrome P450 2A6 in human liver microsomes	34	15
10316	4	10316 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 277(3):1195-1199 Fulton D; Balazy M; McGiff JC; Quilley J Possible contribution of platelet cyclooxygenase to the renal vascular action of 5,6-epoxyeicosatrienoic acid	14	8
10317	15	10317 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 277(3):1710-1718 Brunner LJ; Bennett WM; Koop DR Selective suppression of rat hepatic microsomal activity during chronic cyclosporine nephrotoxicity	11	4
10318	8	10318 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 278(3):1018-1027 Kitteringham NR; Davis C; Howard N; Pirmohamed M; Park BK Interindividual and interspecies variation in hepatic microsomal epoxide hydrolase activity: Studies, with cis- stilbene oxide, carbamazepine 10,11-epoxide and naphthalene	21	0
10319	26	10319 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 278(3):1188-1194 McCallum GP; Weedon AC; Krug P; Bend JR Microsomal cytochrome P450 peroxygenase metabolism of arachidonic acid in guinea pig liver	3	2
10320	24	10320 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 278(3):1383-1391 Chang TKH; Bellward GD Peripubertal androgen imprinting of rat hepatic cytochrome P450 2C11 and steroid 5 alpha-reductase: Pretranslational regulation and impact on microsomal drug activation	9	2
10321	3	10321 1996 JOURNAL OF PLANT PHYSIOLOGY 149(5):633-635 Loerwald B; Clemens S; Barz W Purification and characterization of the NADPH-cytochrome P-450 (cytochrome c) reductase from chickpea	1	0
10322	12	10322 1996 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 56(1-6):151-159 Toda K; Nomoto S; Shizuta Y Identification and characterization of transcriptional regulatory elements of the human aromatase cytochrome P450 gene (CYP19)	11	2
10323	11	10323 1996 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 58(5-6):599-603 Swierczynski J; Mayer D Dehydroepiandrosterone-induced lipid peroxidation in rat liver mitochondria	8	1
10324	1	10324 1996 JOURNAL OF SUBMICROSCOPIC CYTOLOGY AND PATHOLOGY 28(1):27-32 Gilroy C; Singh A; Chu I; Villeneuve DC Toxicity of PCB 156 in the rat liver: An ultrastructural and biochemical study	2	0
10325	9	10325 1996 JOURNAL OF SURGICAL RESEARCH 61(2):361-366 Izuishi K; Ichikawa Y; Hossain MA; Maeba T; Maeta H; Tanaka S Effects of cold preservation and reperfusion on microsomal cytochrome P-450-linked monooxygenase system of the rat liver	7	1
10326	4	10326 1996 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 118(28):6547-6555 Choi SY; Eaton PE; Hollenberg PF; Liu KE; Lippard SJ; Newcomb M; Putt DA; Upadhyaya SP; Xiong YS Regiochemical variations in reactions of methylcubane with tert-butoxyl radical, cytochrome P-450 enzymes, and a methane monooxygenase system	58	5
10327	6	10327 1996 JOURNAL OF THE INDIAN CHEMICAL SOCIETY 73(12):637-645 Chauhan SMS Biomimetic oxidation of organic substrates by chemical models of cytochrome P-450 and related heme monooxygenases	4	1
10328	6	10328 1996 JOURNAL OF THE NATIONAL CANCER INSTITUTE 88(3-4):183-192 Zang EA; Wynder EL Differences in lung cancer risk between men and women: Examination of the evidence	142	3
10329	3	10329 1996 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 47(5):443-451 Markiewicz KV; Howie LE; Safe SH; Donnelly KC Mutagenic potential of binary and complex mixtures using different enzyme induction systems	5	0
10330	3	10330 1996 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 49(3):301-318 Chu I; Villeneuve DC; Yagminas A; Lecavalier P; Poon R; Hakansson H; Ahlborg UG; Valli VE; Kennedy SW; Bergman A; Seegal RF; Feeley M Toxicity of 2,4,4'-trichlorobiphenyl in rats following 90-day dietary exposure	10	1
10331	6	10331 1996 KIDNEY INTERNATIONAL 49(2):362-369 Baliga R; Zhang ZW; Baliga M; Shah SV Evidence for cytochrome P-450 as a source of catalytic iron in myoglobinuric acute renal failure	21	5
10332	18	10332 1996 LIPIDS 31(5):453-487 Smith LL Review of progress in sterol oxidations: 1987-1995	72	0
10333	106	10333 1996 LIPIDS 31(10):1003-1021 Oliw EH; Bylund J; Herman C Bisallylic hydroxylation and epoxidation of polyunsaturated fatty acids by cytochrome P450	21	13
10334	1	10334 1996 MARINE ENVIRONMENTAL RESEARCH 42(1-4):1-6 Boyle SM; James MO Cross-reactivity of an antibody to spiny lobster P450 2L with microsomes from other species	6	4
10335	4	10335 1996 MARINE ENVIRONMENTAL RESEARCH 42(1-4):297-301 Wootton AN; Goldfarb PS; Lemaire P; OHara SCM; Livingstone DR Characterization of the presence and seasonal variation of a CYP1A-like enzyme in digestive gland of the common mussel, Mytilus edulis	15	5
10336	4	10336 1996 MEDICAL SCIENCE RESEARCH 24(4):257-259 Watanabe M; Nakura H; Tateishi T; Tanaka H; Kumai T; Kobayashi S Reduced hepatic drug-metabolising enzyme activities in spontaneously hyperlipidaemic rat as an animal model of hypercholesterolaemia	7	1
10337	9	10337 1996 MOLECULAR & GENERAL GENETICS 250(6):725-733 vanNistelrooy JGM; vandenBrink JM; vanKan JAL; vanGorcom RFM; deWaard MA Isolation and molecular characterisation of the gene encoding eburicol 14 alpha-demethylase (CYP51) from Penicillium italicum	29	14
10338	8	10338 1996 MOLECULAR & GENERAL GENETICS 251(3):290-297 Dunkov BC; RodriguezArnaiz R; Pittendrigh B; FfrenchConstant RH; Feyereisen R Cytochrome P450 gene clusters in Drosophila melanogaster	45	18
10339	16	10339 1996 MOLECULAR AND CELLULAR ENDOCRINOLOGY 120(1):77-83 Li H; Liu SQ; Kemper B Sex- and tissue-specific expression of a cytochrome P450 2C2- luciferase transgene	3	1
10340	15	10340 1996 MOLECULAR ENDOCRINOLOGY 10(11):1350-1357 Zhao Y; Nichols JE; Valdez R; Mendelson CR; Simpson ER Tumor necrosis factor-alpha stimulates aromatase gene expression in human adipose stromal cells through use of an activating protein-1 binding site upstream of promoter 1.4	29	4
10341	3	10341 1996 MOLECULAR GENETICS AND EVOLUTION OF PESTICIDE RESISTANCE 645():62-71 DeWaard MA Molecular genetics of resistance in fungi to azole fungicides	13	2
10342	12	10342 1996 MOLECULAR MARINE BIOLOGY AND BIOTECHNOLOGY 5(1):84-92 Husoy AM; Straetkvern KO; Maaseide NP; Olsen SO; Goksoyr A Polyclonal and monoclonal antibodies against immunoaffinity- purified Atlantic cod (Gadus morhua L) CYP1A	13	2
10343	22	10343 1996 MOLECULAR MICROBIOLOGY 20(6):1115-1125 Munro AW; Lindsay JG Bacterial cytochromes P-450	58	16
10344	15	10344 1996 MOLECULAR PHARMACOLOGY 49(1):63-72 Schuetz JD; Schuetz EG; Thottassery JV; Guzelian PS; Strom S; Sun D Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells	50	21
10345	16	10345 1996 MOLECULAR PHARMACOLOGY 49(2):234-243 Leeder JS; Gaedigk A; Lu XL; Cook VA Epitope mapping studies with human anti-cytochrome P450 3A antibodies	28	4
10346	21	10346 1996 MOLECULAR PHARMACOLOGY 49(2):276-287 Webb SJ; Xiao GH; Geoghegan TE; Prough RA Regulation of CYP4A expression in rat by dehydroepiandrosterone and thyroid hormone	16	10
10347	9	10347 1996 MOLECULAR PHARMACOLOGY 49(2):329-337 Sterling K; Bresnick E Oct-1 transcription factor is a negative regulator of rat CYP1A1 expression via an octamer sequence in its negative regulatory element	22	5
10348	2	10348 1996 MOLECULAR PHARMACOLOGY 49(3):547-555 Rossi L; DeAngelis I; Pedersen JZ; Marchese E; Stammati A; Rotilio G; Zucco F N-[5-nitro-2-furfurylidene]-3-amino-2-oxazolidinone activation by the human intestinal cell line Caco-2 monitored through noninvasive electron spin resonance spectroscopy	8	0
10349	17	10349 1996 MOLECULAR PHARMACOLOGY 49(5):814-821 Rao DNR; Yang MX; Lasker JM; Cederbaum AI 1-hydroxyethyl radical formation during NADPH- and NADH- dependent oxidation of ethanol by human liver microsomes	18	0
10350	9	10350 1996 MOLECULAR PHARMACOLOGY 49(6):1113-1121 Ding XX; Spink DC; Bhama JK; Sheng JJ; Vaz ADN; Coon MJ Metabolic activation of 2,6-dichlorobenzonitrile, an olfactory- specific toxicant, by rat, rabbit, and human cytochromes p450	21	9
10351	18	10351 1996 MOLECULAR PHARMACOLOGY 50(1):10-16 Barwick JL; Quattrochi LC; Mills AS; Potenza C; Tukey RH; Guzelian PS Trans-species gene transfer for analysis of glucocorticoid- inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes	66	26
10352	12	10352 1996 MOLECULAR PHARMACOLOGY 50(1):67-74 Peters JM; Zhou YC; Ram PA; Lee SST; Gonzalez FJ; Waxman DJ Peroxisome proliferator-activated receptor alpha required for gene induction by dehydroepiandrosterone-3 beta-sulfate	58	13
10353	11	10353 1996 MOLECULAR PHARMACOLOGY 50(2):326-333 Lecoeur S; Andre C; Beaune PH Tienilic acid-induced autoimmune hepatitis: Anti-liver and - kidney microsomal type 2 autoantibodies recognize a three-site conformational epitope on cytochrome P4502C9	25	5
10354	9	10354 1996 MOLECULAR PHARMACOLOGY 50(2):342-350 Hedlund E; Wyss A; Kainu T; Backlund M; Kohler C; PeltoHuikko M; Gustafsson JA; Warner M Cytochrome P4502D4 in the brain: Specific neuronal regulation by clozapine and toluene	16	9
10355	7	10355 1996 MOLECULAR PHARMACOLOGY 50(3):474-481 Jover R; Lindberg RLP; Meyer UA Role of heme in cytochrome P450 transcription and function in mice treated with lead acetate	11	4
10356	15	10356 1996 MOLECULAR PHARMACOLOGY 50(4):781-788 Liu C; Zhuo XL; Gonzalez FJ; Ding XX Baculovirus-Mediated expression and characterization of rat CYP2A3 and human CYP2A6: Role in metabolic activation of nasal toxicants	38	15
10357	18	10357 1996 MOLECULAR PHARMACOLOGY 50(4):856-863 Wright MC; Wang XJ; Pimenta M; Ribeiro V; Paine AJ; Lechner MC Glucocorticoid receptor-independent transcriptional induction of cytochrome P450 3A1 by metyrapone and its potentiation by glucocorticoid	22	14
10358	24	10358 1996 MOLECULAR PHARMACOLOGY 50(5):1111-1117 Zeldin DC; Foley J; Ma JX; Boyle JE; Pascual JMS; Moomaw CR; Tomer KB; Steenbergen C; Wu S CYP2J subfamily P450s in the lung: Expression, localization, and potential functional significance	38	22
10359	4	10359 1996 MOLECULAR PLANT-MICROBE INTERACTIONS 9(6):483-491 Hirschi K; VanEtten H Expression of the pisatin detoxifying genes (PDA) of Nectria haematococca in vitro and in planta	9	3
10360	3	10360 1996 MOLECULAR PLANT-MICROBE INTERACTIONS 9(9):787-792 Ciuffetti LM; VanEtten HD Virulence of a pisatin demethylase-deficient Nectria haematococca MPVI isolate is increased by transformation with a pisatin demethylase gene	23	4
10361	4	10361 1996 MOLECULAR REPRODUCTION AND DEVELOPMENT 43(4):428-436 Stromstedt M; Keeney DS; Waterman MR; Paria BC; Conley AJ; Dey SK Preimplantation mouse blastocysts fail to express CYP genes required for estrogen biosynthesis	12	1
10362	16	10362 1996 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 350(1):43-50 Negishi M; Iwasaki M; Juvonen RO; Sueyoshi T; Darden TA; Pedersen LG Structural flexibility and functional versatility of cytochrome P450 and rapid evolution	18	10
10363	5	10363 1996 NATURE STRUCTURAL BIOLOGY 3(7):632-637 CuppVickery JR; Han O; Hutchinson CR; Poulos TL Substrate-assisted catalysis in cytochrome P450eryF	34	12
10364	4	10364 1996 NATURWISSENSCHAFTEN 83(1):32-35 Paul RJ; Schneckenburger H Oxygen concentration and the oxidation-reduction state of yeast: Determination of free/bound NADH and flavins by time- resolved spectroscopy	8	0
10365	3	10365 1996 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 354(1):53-58 Lin WW; Wang CW SK&F 96365 inhibits carbachol induced phosphoinositide turnover in human neuroblastoma SH-SY5Y and rat cerebellar granule cells	2	0
10366	11	10366 1996 NETHERLANDS JOURNAL OF MEDICINE 48(6):237-243 Kerremans ALM Cytochrome P450 isoenzymes - Importance for the internist	13	4
10367	20	10367 1996 NITRIC OXIDE, PT A - SOURCES AND DETECTION OF NO; NO SYNTHASE 268():460-472 McMillan K; Salerno JC; Masters BSS Nitric oxide synthases: Analogies to cytochrome P450 monooxygenases and characterization of recombinant rat neuronal nitric oxide synthase hemoprotein	5	0
10368	2	10368 1996 NUTRITION REVIEWS 54(10):295-317 Beard JL; Dawson H; Pinero DJ Iron metabolism: A comprehensive review	48	0
10369	1	10369 1996 OCL-OLEAGINEUX CORPS GRAS LIPIDES 3(3):182-195 Leger CL Oxidation, antioxidant substances and oxidative stress: A critical review of the connection with ageing	1	0
10370	33	10370 1996 PATHOLOGY 28(2):148-155 McKinnon RA; McManus ME Localization of cytochromes P450 in human tissues: Implications for chemical toxicity	11	1
10371	11	10371 1996 PEROXISOMES: BIOLOGY AND ROLE IN TOXICOLOGY AND DISEASE 804():328-340 Gibson GG Peroxisome proliferators and cytochrome P4504A induction	8	4
10372	8	10372 1996 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 55(3):172-179 Danielson PB; Gloor SL; Roush RT; Fogleman JC Cytochrome P450-mediated resistance to isoquinoline alkaloids and susceptibility to synthetic insecticides in Drosophila	7	2
10373	5	10373 1996 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 56(1):44-52 Kishimoto D; Kurihara N Effects of cytochrome P450 antibodies on the oxidative demethylation of methoxychlor catalyzed by rat liver microsomal cytochrome P450 isozymes: Isozyme specificity and alteration of enantiotopic selectivity	1	0
10374	115	10374 1996 PHARMACOGENETICS 6(1):1-42 Nelson DR; Koymans L; Kamataki T; Stegeman JJ; Feyereisen R; Waxman DJ; Waterman MR; Gotoh O; Coon MJ; Estabrook RW; Gunsalus IC; Nebert DW P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature	1208	1209
10375	12	10375 1996 PHARMACOGENETICS 6(1):103-111 Nagata K; Murayama N; Miyata M; Shimada M; Urahashi A; Yamazoe Y; Kato R Isolation and characterization of a new rat P450 (CYP3A18) cDNA encoding P450(6 beta-2) catalyzing testosterone 6 beta- and 16 alpha-hydroxylations	15	7
10376	14	10376 1996 PHARMACOGENETICS 6(2):159-176 Fuhr U; Rost KL; Engelhardt R; Sachs M; Liermann D; Belloc C; Beaune P; Janezic S; Grant D; Meyer UA; Staib AH Evaluation of caffeine as a test drug for CYPIA2, NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations	49	9
10377	16	10377 1996 PHARMACOGENETICS 6(3):203-211 Carriere V; Berthou F; Baird S; Belloc C; Beaune P; deWaziers I Human cytochrome P450 2E1 (CYP2E1): From genotype to phenotype	62	14
10378	5	10378 1996 PHARMACOGENETICS 6(3):273-277 Roy NK; Konkle B; Wirgin I Characterization of CYP1A1 gene regulatory elements in cancer- prone Atlantic tomcod	11	2
10379	18	10379 1996 PHARMACOGENETICS 6(5):429-439 Stubbins MJ; Harries LW; Smith G; Tarbit MH; Wolf CR Genetic analysis of the human cytochrome P450 CYP2C9 locus	97	14
10380	7	10380 1996 PHARMACOGENETICS 6(5):449-457 Nakamura K; Yokoi T; Inoue K; Shimada N; Ohashi N; Kume T; Kamataki T CYP2D6 is the principal cytochrome P450 responsible for the metabolism of the histamine H-1 antagonist promethazine in human liver microsomes	21	9
10381	4	10381 1996 PHARMAZIE 51(1):46-51 Endres HGE; Henschel L; Merkel U; Hippius M; Hoffmann A Lack of pharmacokinetic interaction between dextromethorphan, coumarin and mephenytoin in man after simultaneous administration	2	0
10382	7	10382 1996 PHARMAZIE 51(7):493-497 Scheuch E; Walter R; Hadasova E; Amon I; Siegmund W Influence of H-2-receptor- and proton pump inhibitors on some functions of the oxydative and conjugative drug metabolism	3	0
10383	6	10383 1996 PHARMAZIE 51(7):498-500 Walter R; Hadasova E; Scheuch E; Siegmund W Effects of streptolysin O, polyriboinosinic-polyribocytidylic acid and combinations with cyclophosphamide on the hepatic arylamine N-acetyltransferase and cytochrome P450-dependent monooxygenases in rats	3	0
10384	3	10384 1996 PHYTOCHEMISTRY 41(2):457-460 Clemens S; Barz W Cytochrome P450-dependent methylenedioxy bridge formation in Cicer arietinum	8	3
10385	50	10385 1996 PHYTOCHEMISTRY 43(1):1-21 Halkier BA Catalytic reactivities and structure/function relationships of cytochrome P450 enzymes	29	4
10386	5	10386 1996 PLANT CELL 8(2):213-239 Nadeau JA; Zhang XS; Li J; ONeill SD Ovule development: Identification of stage-specific and tissue- specific cDNAs	52	2
10387	6	10387 1996 PLANT CELL 8(6):959-969 Bishop GJ; Harrison K; Jones JDG The tomato Dwarf gene isolated by heterologous transposon tagging encodes the first member of a new cytochrome P450 family	62	10
10388	6	10388 1996 PLANT MOLECULAR BIOLOGY 31(2):255-265 Czernic P; Huang HC; Marco Y Characterization of hsr201 and hsr515, two tobacco genes preferentially expressed during the hypersensitive reaction provoked by phytopathogenic bacteria	25	4
10389	16	10389 1996 PLANT PHYSIOLOGY 110(3):1035-1046 Frank MR; Deyneka JM; Schuler MA Cloning of wound-induced cytochrome P450 monooxygenases expressed in pea	31	12
10390	15	10390 1996 PLANT PHYSIOLOGY 112(4):1411-1419 Schuler MA The role of cytochrome P450 monooxygenases in plant-insect interactions	24	7
10391	2	10391 1996 POLYCYCLIC AROMATIC COMPOUNDS 8(2-3):75-92 Genevois C; Brandt HCA; Bartsch H; ObrechtPflumio S; Wild CP; Castegnaro M Formation of DNA adducts in skin, lung and lymphocytes after skin painting of rats with undiluted bitumen or coal-tar fume condensates	11	1
10392	4	10392 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(4):1418-1422 Brown DW; Yu JH; Kelkar HS; Fernandes M; Nesbitt TC; Keller NP; Adams TH; Leonard TJ Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans	118	6
10393	3	10393 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(13):6536-6541 Zaphiropoulos PG Circular RNAs from transcripts of the rat cytochrome P450 2C24 gene: Correlation with exon skipping	17	3
10394	9	10394 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(14):6869-6874 Meyer K; Cusumano JC; Somerville C; Chapple CCS Ferulate-5-hydroxylase from Arabidopsis thaliana defines a new family of cytochrome P450-dependent monooxygenases	59	7
10395	19	10395 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(22):12200-12205 Hung CF; Holzmacher R; Connolly E; Berenbaum MR; Schuler MA Conserved promoter elements in the CYP6B gene family suggest common ancestry for cytochrome P450 monooxygenases mediating furanocoumarin detoxification	26	7
10396	2	10396 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(24):13552-13554 Estabrook RW; Rainey WE Twinkle, twinkle little StAR, how we wonder what you are	2	2
10397	4	10397 1996 PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS 54(1):3-16 Ara G; Teicher BA Cyclooxygenase and lipoxygenase inhibitors in cancer therapy	35	1
10398	3	10398 1996 PROTEIN ENGINEERING 9(7):555-558 Sun YL; Xie Y; Wang YH; Xiao GT; Huang ZX The influence of Glu44 and Glu56 of cytochrome b(5) on the protein structure and interaction with cytochrome c	13	2
10399	10	10399 1996 PROTEIN ENGINEERING 9(9):755-766 Chang YT; Loew GH Construction and evaluation of a three-dimensional structure of cytochrome P450choP enzyme (CYP105C1)	12	5
10400	5	10400 1996 PROTEIN EXPRESSION AND PURIFICATION 8(1):41-47 Barber MJ; Quinn GB High-level expression in Escherichia coli of the soluble, catalytic domain of rat hepatic cytochrome b(5) reductase	5	3

#	Cited nodes	Nodes / Authors	GCS	LCS
10401	17	10401 1996 PROTEIN EXPRESSION AND PURIFICATION 8(4):439-446 Onderwater RCA; Goeptar AR; Levering PR; Vos RME; Konings PNM; Doehmer J; Commandeur JNM; Vermeulen NPE The use of macroporous microcarriers for the large-scale growth of V79 cells genetically designed to express single human cytochrome p450 isoenzymes and for the characterization of the expressed cytochrome p450	1	1
10402	16	10402 1996 PSYCHOPHARMACOLOGY BULLETIN 32(2):205-217 Lin KM; Poland RE; Wan YJY; Smith MW; Lesser IM The evolving science of pharmacogenetics: Clinical and ethnic perspectives	20	2
10403	3	10403 1996 PSYCHOPHARMACOLOGY BULLETIN 32(2):259-263 Hudziak JJ; Geller B Interethnic psychopharmacologic research in children and adolescents	2	0
10404	6	10404 1996 PSYCHOPHARMACOLOGY BULLETIN 32(4):555-568 Carson SW Pharmacokinetic and pharmacodynamic drug interactions with polypharmacotherapy of treatment-resistant affective and obsessive-compulsive disorders	2	0
10405	6	10405 1996 RESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY 91(2):149-159 Carcillo JA; Parise RA; Adedoyin A; Frye R; Branch RA; Romkes M CYP2D6 mRNA expression in circulating peripheral blood mononuclear cells correlates with in vivo debrisoquine hydroxylase activity in extensive metabolizers	15	6
10406	11	10406 1996 REVIEWS OF PHYSIOLOGY BIOCHEMISTRY AND PHARMACOLOGY, 128 128():1-97 Geley S; Fiegl M; Hartmann BL; Kofler R Genes mediating glucocorticoid effects and mechanisms of their regulation	20	0
10407	140	10407 1996 REVIEWS OF PHYSIOLOGY BIOCHEMISTRY AND PHARMACOLOGY, VOL 127 127():137-221 Bernhardt R Cytochrome P450: Structure, function, and generation of reactive oxygen species	37	11
10408	21	10408 1996 REVUE DE MEDECINE VETERINAIRE 147(12):879-892 Guerre P; Galtier P; Burgat V Metabolism and susceptibility to aflatoxins toxicity.	2	0
10409	9	10409 1996 SEMINARS IN ONCOLOGY 23(4):10-20 Brodie AMH; Njar VCO Aromatase inhibitors and breast cancer	47	3
10410	3	10410 1996 SEMINARS IN REPRODUCTIVE ENDOCRINOLOGY 14(4):287-297 Erickson GF Physiologic basis of ovulation induction	9	0
10411	7	10411 1996 TETRAHEDRON LETTERS 37(9):1425-1428 Heckmann B; Mioskowski C; Lumin S; Falck JR; Wei SZ; Capdevila JH Chiral acetals: Stereocontrolled syntheses of 16-, 17-, and 18- hydroxyeicosatetraenoic acids, cytochrome P-450 arachidonate metabolites	9	1
10412	8	10412 1996 THERAPEUTIC DRUG MONITORING 18(4):393-396 Brosen K Drug-metabolizing enzymes and therapeutic drug monitoring in psychiatry	41	1
10413	1	10413 1996 THERIOGENOLOGY 45(7):1327-1349 Milvae RA; Hinckley ST; Carlson JC Luteotropic and luteolytic mechanisms in the bovine corpus luteum	24	0
10414	15	10414 1996 TOXICOLOGIC PATHOLOGY 24(1):45-57 Parkinson A An overview of current cytochrome P450 technology for assessing the safety and efficacy of new materials	78	19
10415	9	10415 1996 TOXICOLOGY 106(1-3):19-26 Sabzevari O; Hatcher M; Kentish P; OSullivan M; Gibson GG Bifonazole, but not the structurally-related clotrimazole, induces both peroxisome proliferation and members of the cytochrome P4504A sub-family in rat liver	5	0
10416	17	10416 1996 TOXICOLOGY 106(1-3):207-219 Belloc C; Baird S; Cosme J; Lecoeur S; Gautier JC; Challine D; deWaziers I; Flinois JP; Beaune PH Human cytochromes P450 expressed in Escherichia coli: Production of specific antibodies	42	10
10417	1	10417 1996 TOXICOLOGY 108(3):185-190 Tsuji R; Isobe N; Kawasaki H Mechanism of prolongation of pentobarbital-induced sleeping time by empenthrin in mice	1	1
10418	3	10418 1996 TOXICOLOGY 109(2-3):129-146 Poon R; Chu I; Davis H; Yagminas AP; Valli VE Systemic toxicity of a bitumen upgrading product in the rat following subchronic dermal exposure	0	0
10419	12	10419 1996 TOXICOLOGY AND APPLIED PHARMACOLOGY 138(1):140-148 CamusRandon AM; Raffalli F; Bereziat JC; McGregor D; Konstandi M; Lang MA Liver injury and expression of cytochromes P450: Evidence that regulation of CYP2A5 is different from that of other major xenobiotic metabolizing CYP enzymes	20	3
10420	14	10420 1996 TOXICOLOGY AND APPLIED PHARMACOLOGY 138(2):231-241 Lake BG; Beamand JA; Wield PT; Price RJ Use of precision-cut liver slices to evaluate species differences in 2-acetylaminofluorene-induced unscheduled DNA synthesis	15	4
10421	5	10421 1996 TOXICOLOGY AND APPLIED PHARMACOLOGY 139(1):42-48 Dowsley TF; Ulreich JB; Bolton JL; Park SS; Forkert PG CYP2E1-dependent bioactivation of 1,1-dichloroethylene in murine lung: Formation of reactive intermediates and glutathione conjugates	18	5
10422	4	10422 1996 TOXICOLOGY AND APPLIED PHARMACOLOGY 140(2):322-327 Bojes HK; Thurman RG Potent peroxisome proliferators inhibit beta-oxidation in the isolated perfused rat liver	2	0
10423	18	10423 1996 TOXICOLOGY AND APPLIED PHARMACOLOGY 141(1):110-116 Zangar RC; Woodcroft KJ; Novak RF Differential effects of ciprofibrate on renal and hepatic cytochrome P450 2E1 expression	9	3
10424	16	10424 1996 TOXICOLOGY AND APPLIED PHARMACOLOGY 141(1):185-194 MartinezLarranaga MR; Anadon A; Diaz MJ; Fernandez R; Sevil B; FernandezCruz ML; Fernandez MC; Martinez MA; Anton R Induction of cytochrome P4501A1 and P4504A1 activities and peroxisomal proliferation by fumonisin B-1	11	1
10425	2	10425 1996 TOXICOLOGY AND APPLIED PHARMACOLOGY 141(1):205-213 Valentine JL; Lee SST; Seaton MJ; Asgharian B; Farris G; Corton JC; Gonzalez FJ; Medinsky MA Reduction of benzene metabolism and toxicity in mice that lack CYP2E1 expression	67	10
10426	2	10426 1996 TOXICOLOGY AND APPLIED PHARMACOLOGY 141(2):507-519 Badger DA; Sauer JM; Hoglen NC; Jolley CS; Sipes IG The role of inflammatory cells and cytochrome P450 in the potentiation of CCl4-induced liver injury by a single dose of retinol	22	3
10427	12	10427 1996 TOXICOLOGY IN VITRO 10(2):129-& GleizesEscala C; Lesca P; Larrieu G; Dupuy J; Pineau T; Galtier P Effect of exposure of rabbit hepatocytes to sulfur-containing anthelmintics (oxfendazole and fenbendazole) on cytochrome P4501A1 expression	8	0
10428	2	10428 1996 TOXICOLOGY IN VITRO 10(5):577-584 Voskoboinik I; Drew R; Ahokas JT Effect of peroxisome proliferator nafenopin on the cytotoxicity of dihaloalkanes in isolated rat hepatocytes	0	0
10429	5	10429 1996 TOXICOLOGY IN VITRO 10(6):655-663 JurimaRomet M; Huang HS; Beck DJ; Li AP Evaluation of drug interactions in intact hepatocytes: Inhibitors of terfenadine metabolism	6	1
10430	5	10430 1996 TOXICOLOGY LETTERS 87(1):25-30 Kodam KM; Adav SS; Govindwar SP Effect of sulfamethazine on phenobarbital and benzo[a]pyrene induced hepatic microsomal mixed function oxidase system in rats	1	1
10431	10	10431 1996 TRACE ELEMENTS AND ELECTROLYTES 13(2):79-84 Takiguchi M; Dhar SK; Kitajiima S; Arizono K; Ariyoshi T Effects on the activities of drug metabolizing enzymes and on the cytochrome P450 3A isozyme in the liver of rats fed on different levels of iron-deficient diet	0	0
10432	11	10432 1996 TRENDS IN CARDIOVASCULAR MEDICINE 6(1):4-10 McGiff JC; Steinberg M; Quilley J Missing links: Cytochrome P450 arachidonate products - A new class of lipid mediators	26	7
10433	4	10433 1996 TUMORI 82(5):417-422 Bajetta E; Celio L; Buzzoni R; Bichisao E Novel non-steroidal aromatase inhibitors: Are there new perspectives in the treatment of breast cancer?	9	0
10434	1	10434 1996 ULTRASTRUCTURAL PATHOLOGY 20(3):275-284 Singh A; Chu I; Villeneuve DC Subchronic toxicity of 2,4,4'-trichlorobiphenyl in the rat liver: An ultrastructural and biochemical study	7	0
10435	10	10435 1996 VETERINARY AND HUMAN TOXICOLOGY 38(1):19-23 Eissa FZ; Qualls CW; Burrows GE; Lish JW Effects of feeding Artemisia filifolia and Helenium flexuosum on rabbit cytochrome p450 isozymes	2	0
10436	17	10436 1996 VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 52 52():129-148 Waterman MR; Keeney DS Signal transduction pathways combining peptide hormones and steroidogenesis	8	0
10437	3	10437 1996 VOPROSY MEDITSINSKOI KHIMII 42(2):119-124 Lashneva NV; Karge E; Knells U; Klinger V; Splinter FK; Tutelan VA In vitro study of selen influence on the formation of active oxygen species and lipid peroxidation in rat liver microsomes	3	0
10438	4	10438 1996 XENOBIOTICA 26(1):9-15 Altuntas TG; Gorrod JW Effect of various potential inhibitors, activators and inducers on the N-oxidation of isomeric aromatic diazines in vitro using rabbit liver microsomal preparations	3	1
10439	1	10439 1996 XENOBIOTICA 26(2):177-187 Teramura T; Tokunaga T; Matsumoto H; Watanabe T; Higuchi S Metabolism of barnidipine hydrochloride, a potent calcium antagonist, in rat and dog	7	0
10440	12	10440 1996 XENOBIOTICA 26(3):297-306 Lake BG; Charzat C; Tredger JM; Renwick AB; Beamand JA; Price RJ Induction of cytochrome P450 isoenzymes in cultured precision- cut rat and human liver slices	49	16
10441	15	10441 1996 XENOBIOTICA 26(4):395-403 Shimada T; Yamazaki H; Guengerich FP Ethnic-related differences in coumarin 7-hydroxylation activities catalyzed by cytochrome P4502A6 in liver microsomes of Japanese and Caucasian populations	36	10
10442	21	10442 1996 XENOBIOTICA 26(5):503-514 Cheung RLH; Lee C; Jones EJ; Riddick DS Lack of effect of methotrexate on the expression of constitutive hepatic cytochromes P450 in the male rat	0	0
10443	5	10443 1996 XENOBIOTICA 26(6):647-666 Bessems JGM; teKoppele JM; VanDijk PA; VanStee LLP; Commandeur JNM; Vermeulen NPE Rat liver microsomal cytochrome P450-dependent oxidation of 3,5-disubstituted analogues of paracetamol	5	0
10444	42	10444 1996 XENOBIOTICA 26(7):723-753 Lewis DFV; Lake BG Molecular modelling of CYP1A subfamily members based on an alignment with CYP102: Rationalization of CYP1A substrate specificity in terms of active site amino acid residues	45	22
10445	13	10445 1996 XENOBIOTICA 26(7):755-763 Eguchi K; Nishibe Y; Baba T; Ohno K Quantitation of cytochrome P450 enzymes (CYP1A1/2, 2B11, 2C21 and 3A12) in dog liver microsomes by enzyme-linked immunosorbent assay	16	5
10446	4	10446 1996 XENOBIOTICA 26(8):793-802 Mae T; Hosoe K; Fujii K; Yamashita K; Yamane T; Hidaka T; Ohashi T In vitro metabolism of a rifamycin derivative by animal and human liver microsomes, whole blood and expressed human CYP3A isoform	7	3
10447	1	10447 1996 XENOBIOTICA 26(8):853-861 Morioka Y; Ohmizo M; Harada M; Goto K; Naito S; Tsutsumi K Metabolism of diethyl 4-[(4-bromo-2- cyanophenyl)carbamoyl]benzylphosphonate in the rat	1	0
10448	19	10448 1996 XENOBIOTICA 26(10):995-1012 Jones EJ; Riddick DS Regulation of constitutive rat hepatic cytochromes P450 by 3- methylcholanthrene	13	2
10449	17	10449 1996 XENOBIOTICA 26(10):1013-1023 Beresford AP; Taylor RJ; Ashcroft JA; Ayrton J; Tucker GT; Ellis SW Expression of human cytochrome P4501A1 (CYP1A1) in Saccharomyces cerevisiae inhibits cell division	2	1
10450	25	10450 1996 XENOBIOTICA 26(10):1067-1086 Lewis DFV; Eddershaw PJ; Goldfarb PS; Tarbit MH Molecular modelling of CYP3A4 from an alignment with CYP102: Identification of key interactions between putative active site residues and CYP3A-specific chemicals	49	29
10451	5	10451 1996 XENOBIOTICA 26(10):1101-1111 Walker DK; Beaumont KC; Stopher DA; Smith DA Pharmacokinetics of a series of bis(methanesulphonamido- arylalkyl)amines in the beagle dog	1	0
10452	19	10452 1996 XENOBIOTICA 26(11):1155-1166 Ono S; Hatanaka T; Miyazawa S; Tsutsui M; Aoyama T; Gonzalez FJ; Satoh T Human liver microsomal diazepam metabolism using cDNA-expressed cytochrome P450s: Role of CYP2B6, 2C19 and the 3A subfamily	41	16
10453	12	10453 1996 XENOBIOTICA 26(11):1181-1193 Parmentier JH; Batt AM; Kremers P Interleukin 1 beta and interleukin 6 repress clofibric acid induction of different P450 isoforms in cultured foetal rat hepatocytes	5	1
10454	12	10454 1996 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN 116(3):192-208 Ariyoshi T Adaptation and protection systems against chemical substances in living body	0	0
10455	14	10455 1996 YEAST 12(4):333-348 Kargel E; Menzel R; Honeck H; Vogel F; Bohmer A; Schunck WH Candida maltosa NADPH-cytochrome P450 reductase: Cloning of a full-length cDNA, heterologous expression in Saccharomyces cerevisiae and function of the N-terminal region for membrane anchoring and proliferation of the endoplasmic reticulum	22	7
10456	11	10456 1996 YEAST 12(6):565-575 Lottermoser K; Schunck WH; Asperger O Cytochromes P450 of the sophorose lipid-producing yeast Candida apicola: Heterogeneity and polymerase chain reaction-mediated cloning of two genes	5	2
10457	26	10457 1997 ACTA GASTRO-ENTEROLOGICA BELGICA 60(1):2-10 Horsmans Y Major cytochrome P-450 families: Implications in health and liver diseases	4	0
10458	2	10458 1997 ACTA PHARMACOLOGICA SINICA 18(2):176-179 Wu B; Wang CW; Xu JR; Zhu JQ Effect of epidermal growth factor on cultured rat hepatocytes poisoned by CCl4	2	0
10459	16	10459 1997 ACTAS LUSO-ESPANOLAS DE NEUROLOGIA PSIQUIATRIA Y CIENCIAS AFINES 25(6):397-409 Lopez-Munoz F; Alamo C; Cuenca E; Rubio G Effect of antidepressant drugs on cytochrome P-450 isoenzymes and its clinical relevance: differential profile	1	0
10460	40	10460 1997 ADVANCED DRUG DELIVERY REVIEWS 27(2-3):99-127 Thummel KE; Kunze KL; Shen DD Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction	45	5
10461	3	10461 1997 ADVANCES IN GENETICS, VOL 35 35():207-252 Timmons L; Shearn A prune/Killer of prune: A conditional dominant lethal interaction in Drosophila	13	0
10462	7	10462 1997 AMERICAN JOURNAL OF HUMAN GENETICS 60(2):265-271 Nebert DW Polymorphisms in drug-metabolizing enzymes: What is their clinical relevance and why do they exist?	93	6
10463	7	10463 1997 AMERICAN JOURNAL OF KIDNEY DISEASES 29(3):465-477 Baliga R; Ueda N; Walker PD; Shah SV Oxidant mechanisms in toxic acute renal failure	69	1
10464	6	10464 1997 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 42(1):C45-C56 Rittenhouse AR; Parker C; Brugnara C; Morgan KG; Alper SL Inhibition of maxi-K currents in ferret portal vein smooth muscle cells by the antifungal clotrimazole	19	0
10465	24	10465 1997 AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 16(3):242-249 Anttila S; Hukkanen J; Hakkola J; Stjernvall T; Beaune P; Edwards RJ; Boobis AR; Pelkonen O; Raunio H Expression and localization of CYP3A4 and CYP3A5 in human lung	35	12
10466	13	10466 1997 ANALYTICAL BIOCHEMISTRY 246(2):253-259 Nithipatikom K; Falck JR; Bhatt RK; Hanke CJ; Campbell WB Determination of 14,15-epoxyeicosatrienoic acid and 14,15- dihydroxyeicosatrienoic acid by fluoroimmunoassay	6	2
10467	7	10467 1997 ANALYTICAL BIOCHEMISTRY 248(1):26-30 Watt KC; Plopper CG; Buckpitt AR Measurement of cytochrome P450 2E1 activity in rat tracheobronchial airways using high-performance liquid chromatography with electrochemical detection	7	2
10468	4	10468 1997 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH 36(1-2):25-41 Aigner A; Wolf S; Gassen HG Transport and detoxication: Principles, approaches, and perspectives for research on the blood-brain barrier	0	0
10469	4	10469 1997 ANNALES D ENDOCRINOLOGIE 58(6):494-502 Miossec P; Archambeaud-Mouveroux F; Teissier MP Inhibition of steroidogenesis by ketoconazole - Therapeutic uses	4	0
10470	2	10470 1997 ANNALS OF CLINICAL BIOCHEMISTRY 34():45-54 Honour JW; Brook CGD Clinical indications for the use of urinary steroid profiles in neonates and children	9	0
10471	11	10471 1997 ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 32 32():295-304 Lin JH; Lu AYH Inhibition of cytochrome P-450 and implications in drug development	9	3
10472	6	10472 1997 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 41(3):654-660 Kempf DJ; Marsh KC; Kumar G; Rodrigues AD; Denissen JF; McDonald E; Kukulka MJ; Hsu A; Granneman GR; Baroldi PA; Sun E; Pizzuti D; Plattner JJ; Norbeck DW; Leonard JM Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir	130	5
10473	16	10473 1997 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 41(4):776-780 Venkateswarlu K; Kelly DE; Kelly SL Characterization of Saccharomyces cerevisiae CYP51 and a CYP51 fusion protein with NADPH cytochrome P-450 oxidoreductase expressed in Escherichia coli	2	1
10474	5	10474 1997 APPLIED AND ENVIRONMENTAL MICROBIOLOGY 63(7):2741-2746 Kullman SW; Matsumura F Identification of a novel cytochrome P-450 gene from the white rot fungus Phanerochaete chrysosporium.	7	2
10475	6	10475 1997 AQUATIC TOXICOLOGY 37(2-3):169-182 Rabergh CMI; Lipsky MM Toxicity of chloroform and carbon tetrachloride in primary cultures of rainbow trout hepatocytes	2	0
10476	3	10476 1997 AQUATIC TOXICOLOGY 37(2-3):237-251 Buhler JLW; Zhao X; Yang YH; Miranda CL; Buhler DR Expression of a constitutive cytochrome P450 (CYP2K1) in livers of rainbow trout (Oncorhynchus mykiss) embryo and sac-fry	3	1
10477	12	10477 1997 AQUATIC TOXICOLOGY 38(4):205-224 Livingstone DR; Nasci C; Sole M; DaRos L; OHara SCM; Peters LD; Fossato V; Wootton AN; Goldfarb PS Apparent induction of a cytochrome P450 with immunochemical similarities to CYP1A in digestive gland of the common mussel (Mytilus galloprovincialis L) with exposure to 2,2',3,4,4',5'- hexachlorobiphenyl and Arochlor 1254	30	7
10478	15	10478 1997 AQUATIC TOXICOLOGY 39(3-4):215-230 Blom S; Forlin L Effects of PCB on xenobiotic biotransformation enzyme activities in the liver and 21-hydroxylation in the head kidney of juvenile rainbow trout	7	2
10479	9	10479 1997 ARCHIV DER PHARMAZIE 330(5):135-140 Gernhardt S; Karge E; Schonecker B; Klinger W Influence of various estrogens on biotransformation: Affinity to cytochrome P-450, structure activity relationships, and scavenger function	1	0
10480	15	10480 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 337(1):1-7 Lu P; Alterman MA; Chaurasia CS; Bambal RB; Hanzlik RP Heme-coordinating analogs of lauric acid as inhibitors of fatty acid omega-hydroxylation	11	7
10481	26	10481 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 337(1):62-68 Mahnke Z; Strotkamp D; Roos PH; Hanstein WG; Chabot GG; Nef P Expression and inducibility of cytochrome P450 3A9 (CYP3A9) and other members of the CYP3A subfamily in rat liver	1	0
10482	18	10482 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 337(2):217-224 Zangar RC; Novak RF Effects of fatty acids and ketone bodies on cytochromes P450 2B, 4A, and 2E1 expression in primary cultured rat hepatocytes	24	4
10483	12	10483 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 337(2):239-250 Gergel D; Misik V; Riesz P; Cederbaum AI Inhibition of rat and human cytochrome P4502E1 catalytic activity and reactive oxygen radical formation by nitric oxide	24	3
10484	19	10484 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 337(2):338-344 Okamoto N; Tsuruta K; Imai Y; Tomura D; Shoun H Fungal P450nor: Expression in Escherichia coli and site- directed mutageneses at the putative distal region	6	4
10485	33	10485 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 338(1):43-49 Toide K; Itoh S; Nagasaka Y; Yanagimoto T; Kamataki T Gene structure of mouse Cyp3a11: Evidence for an enhancer element within its 5' flanking sequences	8	4
10486	18	10486 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 338(2):157-164 Richardson TH; Griffin KJ; Jung F; Raucy JL; Johnson EF Targeted antipeptide antibodies to cytochrome P450 2C18 based on epitope mapping of an inhibitory monoclonal antibody to P450 2C5	22	7
10487	8	10487 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 338(2):193-200 Ogo A; Waterman MR; Kagawa N cAMP-dependent transactivation involving the homeodomain protein Pbx1	9	2
10488	13	10488 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 339(1):55-63 Yuan W; Sequeira DJ; Cawley GF; Eyer CS; Backes WL Time course for the modulation of hepatic cytochrome P450 after administration of ethylbenzene and its correlation with toluene metabolism	7	2
10489	12	10489 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 339(1):85-91 Igarashi T; Sakuma T; Isogai M; Nagata R; Kamataki T Marmoset liver cytochrome P450s: Study for expression and molecular cloning of their cDNAs	10	5
10490	14	10490 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 339(1):107-114 vonWachenfeldt C; Richardson TH; Cosme J; Johnson EF Microsomal P450 2C3 is expressed as a soluble dimer in Escherichia coli following modifications of its N-terminus	22	13
10491	2	10491 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 339(1):125-135 Radi R; Rubbo H; Bush K; Freeman BA Xanthine oxidase binding to glycosaminoglycans: Kinetics and superoxide dismutase interactions of immobilized xanthine oxidase-heparin complexes	18	0
10492	14	10492 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 339(1):218-225 Shet MS; Fisher CW; Estabrook RW The function of recombinant cytochrome P450s in intact Escherichia coli cells: The l7 alpha-hydroxylation of progesterone and pregnenolone by p450c17	20	20
10493	6	10493 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 339(2):298-304 Nishino H; Nakaya J; Nishi S; Kurosawa T; Ishibashi T Temperature-induced differential kinetic properties between an initial burst and the following steady state in membrane-bound enzymes: Studies on lathosterol 5-desaturase	4	0
10494	7	10494 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 340(1):19-26 Puntarulo S; Cederbaum AI Inhibition of ferritin-stimulated microsomal production of reactive oxygen intermediates by nitric oxide	9	0
10495	17	10495 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 340(2):208-214 Hua ZC; Zhang QY; Su T; Lipinskas TW; Ding XX cDNA cloning, heterologous expression, and characterization of mouse CYP2G1, an olfactory-specific steroid hydroxylase	11	10
10496	18	10496 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 340(2):215-218 Yanagimoto T; Itoh S; Sawada M; Kamataki T Mouse cytochrome P450 (Cyp3a11): Predominant expression in liver and capacity to activate aflatoxin B-1	24	11
10497	18	10497 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 340(2):231-238 Sevrioukova I; Truan G; Peterson JA Reconstitution of the fatty acid hydroxylase activity of cytochrome P450BM-3 utilizing its functional domains	10	8
10498	17	10498 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 340(2):270-278 Zhang QY; Ding XX; Kaminsky LS cDNA cloning, heterologous expression, and characterization of rat intestinal CYP2J4	15	9
10499	13	10499 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 341(1):104-111 Maughan JA; Nugent JHA; Hallahan DL Expression of CYP71B7, a cytochrome P450 expressed sequence tag from Arabidopsis thaliana	2	2
10500	15	10500 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 341(2):229-237 Kolesanova EF; Kozin SA; Rumyantsev AB; Jung C; Hoa GHB; Archakov AI Epitope mapping of cytochrome P450cam (CYP101)	8	0

Page 21:  1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  23  24  25  26  27
Generated by: HistCite(Vlad). Version: 2003.05.01