#	Cited nodes	Nodes / Authors	GCS	LCS
8601	2	8601 1993 EAST AFRICAN MEDICAL JOURNAL 70(3):151-153 NYANDIEKA HS; WAKHISI J THE IMPACT OF VITAMINS A,C,E, AND SELENIUM COMPOUND ON PREVENTION OF LIVER-CANCER IN RATS	2	0
8602	38	8602 1993 ENDOCRINE RESEARCH 19(4):223-258 NARASIMHULU S ON THE MODEL CONTROVERSY FOR SUBSTRATE-INDUCED SPIN-STATE TRANSITION IN CYTOCHROME-P450 - (A NEW PERSPECTIVE)	1	1
8603	8	8603 1993 ENDOCRINOLOGY 132(5):1977-1982 YANG XM; IWAMOTO K; WANG M; ARTWOHL J; MASON JI; PANG SY INHERITED CONGENITAL ADRENAL-HYPERPLASIA IN THE RABBIT IS CAUSED BY A DELETION IN THE GENE ENCODING CYTOCHROME-P450 CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME	29	4
8604	2	8604 1993 ENDOCRINOLOGY 132(6):2438-2444 XIONG YT; HALES DB THE ROLE OF TUMOR-NECROSIS-FACTOR-ALPHA IN THE REGULATION OF MOUSE LEYDIG-CELL STEROIDOGENESIS	59	2
8605	13	8605 1993 ENDOCRINOLOGY 132(6):2498-2506 LIN D; BLACK SM; NAGAHAMA Y; MILLER WL STEROID 17-ALPHA-HYDROXYLASE AND 17,20-LYASE ACTIVITIES OF P450C17 - CONTRIBUTIONS OF SERINE(106) AND P450 REDUCTASE	76	30
8606	12	8606 1993 ENVIRONMENTAL HEALTH PERSPECTIVES 100():169-176 GOLDSTEIN JA; FALETTO MB ADVANCES IN MECHANISMS OF ACTIVATION AND DEACTIVATION OF ENVIRONMENTAL CHEMICALS	27	1
8607	4	8607 1993 ENVIRONMENTAL HEALTH PERSPECTIVES 100():189-200 VANDENHEUVEL JP; LUCIER G ENVIRONMENTAL TOXICOLOGY OF POLYCHLORINATED DIBENZO-P-DIOXINS AND POLYCHLORINATED DIBENZOFURANS	48	2
8608	9	8608 1993 ENVIRONMENTAL HEALTH PERSPECTIVES 101():109-112 HIRVONEN A; HUSGAFVELPURSIAINEN K; ANTTILA S; KARJALAINEN A; VAINIO H POLYMORPHISM IN CYP1A1 AND CYP2D6 GENES - POSSIBLE ASSOCIATION WITH SUSCEPTIBILITY TO LUNG-CANCER	16	0
8609	2	8609 1993 ENVIRONMENTAL HEALTH PERSPECTIVES 101():117-120 IDLE JR; DALY AK NEW OPPORTUNITIES IN CANCER RISK-EVALUATION USING PCR-BASED DNA ANALYSIS FOR CYP2D6	3	0
8610	2	8610 1993 ENVIRONMENTAL HEALTH PERSPECTIVES 101(6):528-536 FARISS MW; BRYSON KF; HYLTON EE; LIPPMAN HR; STUBIN CH; ZHAO XG PROTECTION AGAINST CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY BY PRETREATING RATS WITH THE HEMISUCCINATE ESTERS OF TOCOPHEROL AND CHOLESTEROL	23	1
8611	19	8611 1993 ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 12(6):989-999 VANDERWEIDEN MEJ; CELANDER M; SEINEN W; VANDENBERG M; GOKSOYR A; FORLIN L INDUCTION OF CYTOCHROME-P450 1A IN FISH TREATED WITH 2,3,7,8- TETRACHLORODIBENZO-P-DIOXIN OR CHEMICALLY CONTAMINATED SEDIMENT	25	5
8612	9	8612 1993 ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 12(9):1619-1626 MYERS CR; SUTHERLAND LA; HAASCH ML; LECH JJ ANTIBODIES TO A SYNTHETIC PEPTIDE THAT REACT SPECIFICALLY WITH RAINBOW-TROUT HEPATIC CYTOCHROME-P450 1A1	18	6
8613	8	8613 1993 EUROPEAN JOURNAL OF BIOCHEMISTRY 213(1):211-216 ELTIS LD; KARLSON U; TIMMIS KN PURIFICATION AND CHARACTERIZATION OF CYTOCHROME-P450(RR1) FROM RHODOCOCCUS-RHODOCHROUS	17	3
8614	8	8614 1993 EUROPEAN JOURNAL OF BIOCHEMISTRY 213(1):383-389 TODA K; SHIZUTA Y MOLECULAR-CLONING OF A CDNA SHOWING ALTERNATIVE SPLICING OF THE 5'-UNTRANSLATED SEQUENCE OF MESSENGER-RNA FOR HUMAN AROMATASE- P-450	40	21
8615	6	8615 1993 EUROPEAN JOURNAL OF BIOCHEMISTRY 213(2):683-687 MCKNIGHT J; CHEESMAN MR; THOMSON AJ; MILES JS; MUNRO AW IDENTIFICATION OF CHARGE-TRANSFER TRANSITIONS IN THE OPTICAL- SPECTRUM OF LOW-SPIN FERRIC CYTOCHROME-P-450 BACILLUS- MEGATERIUM	20	5
8616	19	8616 1993 EUROPEAN JOURNAL OF BIOCHEMISTRY 214(3):735-745 MAPOLES J; BERTHOU F; ALEXANDER A; SIMON F; MENEZ JF MAMMALIAN PC-12 CELL GENETICALLY-ENGINEERED FOR HUMAN CYTOCHROME-P450 2E1 EXPRESSION	26	8
8617	34	8617 1993 EUROPEAN JOURNAL OF BIOCHEMISTRY 218(2):355-361 PEYRONNEAU MA; RENAUD JP; JAOUEN M; URBAN P; CULLIN C; POMPON D; MANSUY D EXPRESSION IN YEAST OF 3 ALLELIC CDNAS CODING FOR HUMAN LIVER P-450 3A4 - DIFFERENT STABILITIES, BINDING-PROPERTIES AND CATALYTIC ACTIVITIES OF THE YEAST-PRODUCED ENZYMES	13	7
8618	19	8618 1993 EUROPEAN JOURNAL OF BIOCHEMISTRY 218(2):585-595 HASHIMOTO H; TOIDE K; KITAMURA R; FUJITA M; TAGAWA S; ITOH S; KAMATAKI T GENE STRUCTURE OF CYP3A4, AN ADULT-SPECIFIC FORM OF CYTOCHROME- P450 IN HUMAN LIVERS, AND ITS TRANSCRIPTIONAL CONTROL	102	51
8619	2	8619 1993 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 18(2):181-185 BIENVENU T; PONS G; REY E; THIROUX G; OLIVE G EFFECT OF PREGNANDIOL ON CAFFEINE METABOLISM IN FEMALE RATS	4	0
8620	13	8620 1993 EUROPEAN JOURNAL OF PHARMACOLOGY 235(1):1-7 ESCALANTE B; OMATA K; SESSA W; LEE SG; FALCK JR; SCHWARTZMAN ML 20-HYDROXYEICOSATETRAENOIC ACID IS AN ENDOTHELIUM-DEPENDENT VASOCONSTRICTOR IN RABBIT ARTERIES	32	13
8621	10	8621 1993 EUROPEAN JOURNAL OF PHARMACOLOGY-ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY SECTION 248(1):7-14 PARK KS; SOHN DH; VEECH RL; SONG BJ TRANSLATIONAL ACTIVATION OF ETHANOL-INDUCIBLE CYTOCHROME-P450 (CYP2E1) BY ISONIAZID	39	4
8622	16	8622 1993 EUROPEAN JOURNAL OF PHARMACOLOGY-ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY SECTION 248(2):95-102 SALONPAA P; HAKKOLA J; PASANEN M; PELKONEN O; VAHAKANGAS K; BATTULA N; NOUSO K; RAUNIO H RETROVIRUS-MEDIATED STABLE EXPRESSION OF HUMAN CYP2A6 IN MAMMALIAN-CELLS	26	16
8623	17	8623 1993 EUROPEAN JOURNAL OF PHARMACOLOGY-ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY SECTION 248(3):251-261 SCHMALIX WA; MASER H; KIEFER F; REEN R; WIEBEL FJ; GONZALEZ F; SEIDEL A; GLATT H; GREIM H; DOEHMER J STABLE EXPRESSION OF HUMAN CYTOCHROME-P450 1A1 CDNA IN V79 CHINESE-HAMSTER CELLS AND METABOLIC-ACTIVATION OF BENZO[A]PYRENE	49	13
8624	4	8624 1993 EXPERIENTIA 49(10):854-858 FERNANDEZLOPEZ JA; SUBIRADE I; FERNANDEZ Y; DELTOUR P; PERIQUET A; MITIJAVILA S CA-EFFLUX, FROM DIRECT MEMBRANE INJURY BY CCL4, IS ELICITED BY AMPHIPHILIC VEHICLES IN-VITRO	1	0
8625	5	8625 1993 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 45(2-3):101-107 JAHN F; REUTER A; KARGE E; DANZ M; KLINGER W AGE-DEPENDENT DIFFERENT INFLUENCE OF CARBON-TETRACHLORIDE ON BIOTRANSFORMATION OF XENOBIOTICS, GLUTATHIONE CONTENT, LIPID- PEROXIDATION AND HISTOPATHOLOGY OF RAT-LIVER	5	0
8626	7	8626 1993 EXPERIMENTAL EYE RESEARCH 56(6):701-708 GUPTA AG; HIRAKATA A; PROIA AD EFFECT OF INHIBITORS OF ARACHIDONIC-ACID METABOLISM ON CORNEAL REEPITHELIALIZATION IN THE RAT	15	0
8627	0	8627 1993 FASEB JOURNAL 7(7):A1206-A1206 SHET MS; FISHER CW; ARLOTTO MP; ESTABROOK RW ENZYMATIC-PROPERTIES OF A RECOMBINANT FUSION PROTEIN CONTAINING THE DOMAINS OF HUMAN P450-3A4 AND RAT NADPH-P450 REDUCTASE	0	0
8628	1	8628 1993 FEBS LETTERS 315(2):153-158 GRESCHNER S; SHARONOV YA; JUNG C SUBSTRATE-INDUCED CHANGES OF THE ACTIVE-SITE ELECTRONIC STATES IN REDUCED CYTOCHROME P450CAM AND THE PHOTOLYSIS PRODUCT OF ITS CO COMPLEX - LOW-TEMPERATURE MAGNETIC CIRCULAR-DICHROISM DATA	5	1
8629	5	8629 1993 FEBS LETTERS 322(1):30-32 FUJIMOTO Y; SHIRABE K; NAGAI T; YUBISUI T; TAKESHITA M ROLE OF LYS-110 OF HUMAN NADH-CYTOCHROME-B(5) REDUCTASE IN NADH BINDING AS PROBED BY SITE-DIRECTED MUTAGENESIS	3	2
8630	16	8630 1993 FEBS LETTERS 322(1):61-64 ORELLANA M; FUENTES O; VALDES E STARVATION EFFECT ON RAT-KIDNEY PEROXISOMAL AND MICROSOMAL FATTY-ACID OXIDATION - A COMPARATIVE-STUDY BETWEEN LIVER AND KIDNEY	11	2
8631	6	8631 1993 FEBS LETTERS 330(2):169-173 UMEMOTO N; KOBAYASHI O; ISHIZAKINISHIZAWA O; TOGURI T CDNAS SEQUENCES ENCODING CYTOCHROME-P450 (CYP71 FAMILY) FROM EGGPLANT SEEDLINGS	17	13
8632	16	8632 1993 FEBS LETTERS 332(1-2):1-8 DEGTYARENKO KN; ARCHAKOV AI MOLECULAR EVOLUTION OF P450 SUPERFAMILY AND P450-CONTAINING MONOOXYGENASE SYSTEMS	42	29
8633	5	8633 1993 FOOD AND CHEMICAL TOXICOLOGY 31(5):377-& LAKE BG; BEAMAND JA; JAPENGA AC; RENWICK A; DAVIES S; PRICE RJ INDUCTION OF CYTOCHROME-P-450-DEPENDENT ENZYME-ACTIVITIES IN CULTURED RAT-LIVER SLICES	56	15
8634	3	8634 1993 FOOD AND CHEMICAL TOXICOLOGY 31(12):963-& LAKE BG; EVANS JG EFFECT OF PRETREATMENT WITH SOME MIXED-FUNCTION OXIDASE ENZYME INDUCERS ON THE ACUTE HEPATOTOXICITY OF COUMARIN IN THE RAT	5	2
8635	4	8635 1993 FREE RADICAL BIOLOGY AND MEDICINE 14(6):583-588 SOHAL RS AGING, CYTOCHROME-OXIDASE ACTIVITY, AND HYDROGEN-PEROXIDE RELEASE BY MITOCHONDRIA	52	0
8636	9	8636 1993 FUNDAMENTAL & CLINICAL PHARMACOLOGY 7(2):69-75 SEREE EJ; PISANO PJ; PLACIDI M; RAHMANI R; BARRA YA IDENTIFICATION OF THE HUMAN AND ANIMAL HEPATIC CYTOCHROMES-P450 INVOLVED IN CLONAZEPAM METABOLISM	20	7
8637	13	8637 1993 FUNDAMENTAL & CLINICAL PHARMACOLOGY 7(6):311-317 PINQUIER JL; JOSEPH X; DELAFORGE M; LEJUS C; BOUCHER JL; DELAUTURE D; KAHAN A; STRAUCH G LACK OF EFFECT OF PHENOBARBITAL ON EX-VIVO LEUKOCYTE OXIDATIVE- METABOLISM IN HEALTHY-VOLUNTEERS	0	0
8638	11	8638 1993 FUNDAMENTAL AND APPLIED TOXICOLOGY 20(1):72-82 HAASCH ML; QUARDOKUS EM; SUTHERLAND LA; GOODRICH MS; LECH JJ HEPATIC CYP1A1 INDUCTION IN RAINBOW-TROUT BY CONTINUOUS FLOWTHROUGH EXPOSURE TO BETA-NAPHTHOFLAVONE	66	15
8639	13	8639 1993 GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE 17(5BIS):H3-H17 PESSAYRE D MECHANISMS OF DRUG-INDUCED LIVER-LESIONS	14	1
8640	12	8640 1993 GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE 17(12):908-912 DUCLOSVALLEE JC; YAMAMOTO AM; CRESTEIL D; ALVAREZ F MEMBERS OF THE CYTOCHROME-P450 FAMILY AND LIVER-KIDNEY MICROSOMES AUTOANTIBODIES - AN ANTIGEN-ANTIBODY RELATION	4	0
8641	14	8641 1993 GASTROENTEROLOGY 104(1):203-216 LOEPER J; DESCATOIRE V; MAURICE M; BEAUNE P; BELGHITI J; HOUSSIN D; BALLET F; FELDMANN G; GUENGERICH FP; PESSAYRE D CYTOCHROMES-P-450 IN HUMAN HEPATOCYTE PLASMA-MEMBRANE - RECOGNITION BY SEVERAL AUTOANTIBODIES	86	16
8642	2	8642 1993 GENE 136(1-2):333-336 NAKAYAMA K; SUWA Y; MIZUKAMI Y; SOGAWA K; FUJIIKURIYAMA Y CLONING AND SEQUENCING OF A NOVEL RAT CYTOCHROME-P450 2B- ENCODING GENE	8	4
8643	2	8643 1993 GENOMICS 16(1):85-89 SHEPHARD EA; DOLPHIN CT; FOX MF; POVEY S; SMITH R; PHILLIPS IR LOCALIZATION OF GENES ENCODING 3 DISTINCT FLAVIN-CONTAINING MONOOXYGENASES TO HUMAN CHROMOSOME-1Q	15	1
8644	5	8644 1993 GENOMICS 18(3):702-704 KOLBLE K REGIONAL MAPPING OF SHORT TANDEM REPEATS ON HUMAN-CHROMOSOME-10 - CYTOCHROME-P450 GENE CYP2E, D10S196, D10S220, AND D10S225	1	0
8645	3	8645 1993 GLIA 8(3):172-182 FISHER M; TRIMMER P; RUTHEL G BERGMANN GLIA REQUIRE CONTINUOUS ASSOCIATION WITH PURKINJE- CELLS FOR NORMAL PHENOTYPE EXPRESSION	8	0
8646	9	8646 1993 HEPATOLOGY 17(2):230-235 CRAIG PI; TAPNER M; FARRELL GC INTERFERON SUPPRESSES ERYTHROMYCIN METABOLISM IN RATS AND HUMAN-SUBJECTS	31	8
8647	15	8647 1993 HEPATOLOGY 17(2):236-245 TAKAHASHI T; LASKER JM; ROSMAN AS; LIEBER CS INDUCTION OF CYTOCHROME P-4502E1 IN THE HUMAN LIVER BY ETHANOL IS CAUSED BY A CORRESPONDING INCREASE IN ENCODING MESSENGER-RNA	116	17
8648	19	8648 1993 HEPATOLOGY 18(5):1254-1262 SCHUETZ EG; SCHUETZ JD; STROM SC; THOMPSON MT; FISHER RA; MOLOWA DT; LI D; GUZELIAN PS REGULATION OF HUMAN LIVER CYTOCHROMES P-450 IN FAMILY 3A IN PRIMARY AND CONTINUOUS-CULTURE OF HUMAN HEPATOCYTES	111	36
8649	6	8649 1993 HISTOCHEMISTRY 99(6):443-451 FRITZ P; BEHRLE E; BEAUNE P; EICHELBAUM M; KROEMER HK DIFFERENTIAL EXPRESSION OF DRUG-METABOLIZING-ENZYMES IN PRIMARY AND SECONDARY LIVER NEOPLASM - IMMUNOHISTOCHEMICAL CHARACTERIZATION OF CYTOCHROME-P4503A AND GLUTATHIONE-S- TRANSFERASE	25	4
8650	2	8650 1993 HUMAN GENETICS 92(1):33-39 MANFRAS BJ; SWINYARD M; RUDERT WA; BALL EJ; LEE PA; KUHNL P; TRUCCO M; BOHM BO ALTERED CYP21 GENES IN HLA-HAPLOTYPES ASSOCIATED WITH CONGENITAL ADRENAL-HYPERPLASIA (CAH) - A FAMILY STUDY	2	0
8651	12	8651 1993 HUMAN GENETICS 92(4):367-372 MURA C; PANSERAT S; VINCENTVIRY M; GALTEAU MM; JACQZAIGRAIN E; KRISHNAMOORTHY R DNA HAPLOTYPE DEPENDENCY OF DEBRISOQUINE 4-HYDROXYLASE (CYP2D6) EXPRESSION AMONG EXTENSIVE METABOLIZERS	11	0
8652	6	8652 1993 HYPERTENSION 22(3):357-364 IMIG JD; FALCK JR; GEBREMEDHIN D; HARDER DR; ROMAN RJ ELEVATED RENOVASCULAR TONE IN YOUNG SPONTANEOUSLY HYPERTENSIVE RATS - ROLE OF CYTOCHROME-P-450	55	12
8653	9	8653 1993 IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 29A(1):62-66 KOCAREK TA; SCHUETZ EG; GUZELIAN PS TRANSIENT INDUCTION OF CYTOCHROME-P450-1A1 MESSENGER-RNA BY CULTURE-MEDIUM COMPONENT IN PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES	24	0
8654	7	8654 1993 INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 23(4):475-480 LAGADIC L; CRESTEIL T ENHANCED INVITRO METABOLISM OF TESTOSTERONE BY MICROSOMES FROM INSECTICIDE-RESISTANT SPODOPTERA-LITTORALIS LARVAE	2	0
8655	2	8655 1993 INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY 7(3-4):167-180 DINGEMANSE J AN UPDATE OF RECENT MOCLOBEMIDE INTERACTION DATA	47	2
8656	3	8656 1993 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 25(1):43-52 DIETZE EC; KUWANO E; HAMMOCK BD THE INTERACTION OF CYTOSOLIC EPOXIDE HYDROLASE WITH CHIRAL EPOXIDES	2	0
8657	6	8657 1993 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 25(2):279-286 LESKOVAC V; PEGGINS JO; TRIVIC S; SVIRCEVIC J; POPOVIC M; STUPAR M REDUCTION OF 1-NITROSO-2-NAPHTHOL BY NADPH IN THE PRESENCE OF LIVER-MICROSOMES	2	1
8658	5	8658 1993 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 25(9):1291-1301 WINDER BS; NOUROOZZADEH J; ISSEROFF RR; MOGHADDAM MF; HAMMOCK BD PROPERTIES OF ENZYMES HYDRATING EPOXIDES IN HUMAN EPIDERMIS AND LIVER	3	0
8659	4	8659 1993 INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER 3(3):159-163 PATEL KR; ASTLEY S; ADAMS DJ; LACEY CJN; ALI SW; WELLS M EXPRESSION OF CYTOCHROME-P450 ENZYMES IN THE CERVIX - AN IMMUNOHISTOCHEMICAL STUDY	4	0
8660	6	8660 1993 INTERNATIONAL JOURNAL OF ONCOLOGY 2(5):731-738 NG SF; WAXMAN DJ ACTIVATION OF THIO-TEPA CYTOTOXICITY TOWARD HUMAN BREAST-CANCER CELLS BY HEPATIC CYTOCHROME-P450	6	2
8661	7	8661 1993 JAPANESE JOURNAL OF CANCER RESEARCH 84(3):265-271 NEMOTO N; SAKURAI J CELL-DENSITY-DEPENDENT EXPRESSION OF CYP1A2 GENE IN MONOLAYER- CULTURED ADULT-MOUSE HEPATOCYTES	7	2
8662	4	8662 1993 JAPANESE JOURNAL OF CANCER RESEARCH 84(12):1320-1321 GELBOIN HV CYTOCHROME-P-450 - THE JAPANESE CONNECTION	0	0
8663	3	8663 1993 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 41(6):858-862 CHELVARAJAN RL; FANNIN FF; BUSH LP STUDY OF NICOTINE DEMETHYLATION IN NICOTIANA-OTOPHORA	19	2
8664	4	8664 1993 JOURNAL OF APPLIED PHYSIOLOGY 74(3):1342-1347 BERTOCCI LA; HALLER RG; LEWIS SF MUSCLE METABOLISM DURING LACTATE INFUSION IN HUMAN PHOSPHOFRUCTOKINASE DEFICIENCY	4	0
8665	6	8665 1993 JOURNAL OF APPLIED PHYSIOLOGY 74(5):2421-2425 GAO YS; VANHOUTTE PM RESPIRATORY EPITHELIUM MODULATES THE RESPONSES OF CANINE BRONCHI TO COOLING	2	0
8666	15	8666 1993 JOURNAL OF BACTERIOLOGY 175(18):6028-6037 ROPP JD; GUNSALUS IC; SLIGAR SG CLONING AND EXPRESSION OF A MEMBER OF A NEW CYTOCHROME-P-450 FAMILY - CYTOCHROME P-450LIN (CYP111) FROM PSEUDOMONAS- INCOGNITA	10	5
8667	18	8667 1993 JOURNAL OF BIOCHEMICAL TOXICOLOGY 8(3):135-144 OKITA JR; CASTLE PJ; OKITA RT CHARACTERIZATION OF CYTOCHROMES-P450 IN LIVER AND KIDNEY OF RATS TREATED WITH DI-(2-ETHYLHEXYL)PHTHALATE	35	12
8668	6	8668 1993 JOURNAL OF BIOCHEMISTRY 113(1):7-12 FUKUDA T; IMAI Y; KOMORI M; NAKAMURA M; KUSUNOSE E; SATOUCHI K; KUSUNOSE M REPLACEMENT OF THR-303 OF P450 2E1 WITH SERINE MODIFIES THE REGIOSELECTIVITY OF ITS FATTY-ACID HYDROXYLASE-ACTIVITY	50	35
8669	11	8669 1993 JOURNAL OF BIOCHEMISTRY 113(2):144-152 NOMURA M; MOROHASHI K; KIRITA S; NONAKA Y; OKAMOTO M; NAWATA H; OMURA T 3 FORMS OF RAT CYP11B GENES - 11 BETA-HYDROXYLASE GENE, ALDOSTERONE SYNTHASE GENE, AND A NOVEL GENE	43	5
8670	12	8670 1993 JOURNAL OF BIOCHEMISTRY 114(3):363-369 UNO T; IMAI Y; NAKAMURA M; OKAMOTO N; FUKUDA T IMPORTANCE OF SUCCESSIVE PROLINES IN THE CARBOXY-TERMINAL REGION OF P450-2C2 AND P450-2C14 FOR THE HYDROXYLASE-ACTIVITIES	5	2
8671	6	8671 1993 JOURNAL OF BIOCHEMISTRY 114(3):445-448 KOMORI M; HIGAMI A; IMAI Y; IMAOKA S; FUNAE Y PURIFICATION AND CHARACTERIZATION OF A FORM OF P450 FROM HORSE LIVER-MICROSOMES	3	0
8672	6	8672 1993 JOURNAL OF BIOCHEMISTRY 114(5):652-657 YAMAZAKI S; SATO K; SUHARA K; SAKAGUCHI M; MIHARA K; OMURA T IMPORTANCE OF THE PROLINE-RICH REGION FOLLOWING SIGNAL-ANCHOR SEQUENCE IN THE FORMATION OF CORRECT CONFORMATION OF MICROSOMAL CYTOCHROME P-450S	70	40
8673	9	8673 1993 JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 25(4):367-375 VINOGRADOV AD KINETICS, CONTROL, AND MECHANISM OF UBIQUINONE REDUCTION BY THE MAMMALIAN RESPIRATORY CHAIN-LINKED NADH-UBIQUINONE REDUCTASE	52	5
8674	10	8674 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(1):269-275 TUCK SF; GRAHAMLORENCE S; PETERSON JA; DEMONTELLANO PRO ACTIVE-SITES OF THE CYTOCHROME-P450(CAM) (CYP101) F87W AND F87A MUTANTS - EVIDENCE FOR SIGNIFICANT STRUCTURAL REORGANIZATION WITHOUT ALTERATION OF CATALYTIC REGIOSPECIFICITY	24	15
8675	4	8675 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(2):1053-1057 PASCO DS; BOYUM KW; ELBI C; SIU CS; FAGAN JB INDUCER-DEPENDENT TRANSCRIPTIONAL ACTIVATION OF THE P4501A2 GENE INVIVO AND IN ISOLATED HEPATOCYTES	18	7
8676	5	8676 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(4):2997-3004 SHAW GC; FULCO AJ INHIBITION BY BARBITURATES OF THE BINDING OF BM3R1 REPRESSOR TO ITS OPERATOR SITE ON THE BARBITURATE-INDUCIBLE CYTOCHROME- P450(BM-3) GENE OF BACILLUS-MEGATERIUM	51	13
8677	17	8677 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(6):4453-4457 HALPERT JR; HE YA ENGINEERING OF CYTOCHROME-P450 2B1 SPECIFICITY - CONVERSION OF AN ANDROGEN 16-BETA-HYDROXYLASE TO A 15-ALPHA-HYDROXYLASE	78	45
8678	14	8678 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(7):5069-5076 TANG CL; HENRY HL OVEREXPRESSION IN ESCHERICHIA-COLI AND AFFINITY PURIFICATION OF CHICK KIDNEY FERREDOXIN	10	2
8679	4	8679 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(9):6293-6298 SONG WC; BAERTSCHI SW; BOEGLIN WE; HARRIS TM; BRASH AR FORMATION OF EPOXYALCOHOLS BY A PURIFIED ALLENE OXIDE SYNTHASE - IMPLICATIONS FOR THE MECHANISM OF ALLENE OXIDE SYNTHESIS	39	14
8680	26	8680 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(9):6402-6407 ZELDIN DC; KOBAYASHI J; FALCK JR; WINDER BS; HAMMOCK BD; SNAPPER JR; CAPDEVILA JH REGIOFACIAL AND ENANTIOFACIAL SELECTIVITY OF EPOXYEICOSATRIENOIC ACID HYDRATION BY CYTOSOLIC EPOXIDE HYDROLASE	55	34
8681	12	8681 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(10):7553-7561 KLEIN ML; FULCO AJ CRITICAL RESIDUES INVOLVED IN FMN BINDING AND CATALYTIC ACTIVITY IN CYTOCHROME-P450(BM-3)	25	15
8682	4	8682 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(11):8350-8355 NAKAHARA K; TANIMOTO T; HATANO K; USUDA K; SHOUN H CYTOCHROME-P-450-55A1 (P-450DNIR) ACTS AS NITRIC-OXIDE REDUCTASE EMPLOYING NADH AS THE DIRECT ELECTRON-DONOR	107	34
8683	10	8683 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(12):9130-9137 MUKAI K; IMAI M; SHIMADA H; ISHIMURA Y ISOLATION AND CHARACTERIZATION OF RAT CYP11B GENES INVOLVED IN LATE STEPS OF MINERALOCORTICOID AND GLUCOCORTICOID SYNTHESES	50	7
8684	14	8684 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(13):9376-9380 KIKUTA Y; KUSUNOSE E; ENDO K; YAMAMOTO S; SOGAWA K; FUJIIKURIYAMA Y; KUSUNOSE M A NOVEL FORM OF CYTOCHROME-P-450 FAMILY-4 IN HUMAN POLYMORPHONUCLEAR LEUKOCYTES - CDNA CLONING AND EXPRESSION OF LEUKOTRIENE-B4 OMEGA-HYDROXYLASE	68	32
8685	3	8685 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(13):9430-9436 WOLFF DJ; DATTO GA; SAMATOVICZ RA THE DUAL-MODE OF INHIBITION OF CALMODULIN-DEPENDENT NITRIC- OXIDE SYNTHASE BY ANTIFUNGAL IMIDAZOLE AGENTS	49	5
8686	2	8686 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(13):9681-9689 ATTAASAFOADJEI E; LAWTON MP; PHILPOT RM CLONING, SEQUENCING, DISTRIBUTION, AND EXPRESSION IN ESCHERICHIA-COLI OF FLAVIN-CONTAINING MONOOXYGENASE 1C1 - EVIDENCE FOR A 3RD GENE SUBFAMILY IN RABBITS	47	6
8687	2	8687 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(16):11639-11654 PASCAL S; TATON M; RAHIER A PLANT STEROL BIOSYNTHESIS - IDENTIFICATION AND CHARACTERIZATION OF 2 DISTINCT MICROSOMAL OXIDATIVE ENZYMATIC SYSTEMS INVOLVED IN STEROL C4-DEMETHYLATION	26	5
8688	22	8688 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(17):12912-12918 LAETHEM RM; BALAZY M; FALCK JR; LAETHEM CL; KOOP DR FORMATION OF 19(S)-HYDROXYEICOSATETRAENOIC, 19(R)- HYDROXYEICOSATETRAENOIC, AND 18(R)-HYDROXYEICOSATETRAENOIC ACIDS BY ALCOHOL-INDUCIBLE CYTOCHROME-P450 2E1	88	48
8689	11	8689 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(17):12919-12924 BRISTOW J; GITELMAN SE; TEE MK; STAELS B; MILLER WL ABUNDANT ADRENAL-SPECIFIC TRANSCRIPTION OF THE HUMAN P450C21A PSEUDOGENE	46	8
8690	15	8690 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(18):13565-13570 KARARA A; MAKITA K; JACOBSON HR; FALCK JR; GUENGERICH FP; DUBOIS RN; CAPDEVILA JH MOLECULAR-CLONING, EXPRESSION, AND ENZYMATIC CHARACTERIZATION OF THE RAT-KIDNEY CYTOCHROME-P-450 ARACHIDONIC-ACID EPOXYGENASE	61	45
8691	19	8691 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(23):17253-17260 PENG HM; DING XX; COON MJ ISOLATION AND HETEROLOGOUS EXPRESSION OF CLONED CDNAS FOR 2 RABBIT NASAL MICROSOMAL PROTEINS, CYP2A10 AND CYP2A11, THAT ARE RELATED TO NASAL MICROSOMAL CYTOCHROME-P450 FORM A	32	20
8692	6	8692 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(23):17317-17325 BEGEOT M; SHETTY U; KILGORE M; WATERMAN M; SIMPSON E REGULATION OF EXPRESSION OF THE CYP11A (P450(SCC)) GENE IN BOVINE OVARIAN LUTEAL CELLS BY FORSKOLIN AND PHORBOL ESTERS	26	4
8693	18	8693 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(23):17384-17391 BOUCHER PD; RUCH RJ; HINES RN SPECIFIC NUCLEAR-PROTEIN BINDING TO A NEGATIVE REGULATORY ELEMENT ON THE HUMAN CYP1A1 GENE	59	26
8694	11	8694 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(23):17628-17633 GRANT DF; STORMS DH; HAMMOCK BD MOLECULAR-CLONING AND EXPRESSION OF MURINE LIVER SOLUBLE EPOXIDE HYDROLASE	43	8
8695	8	8695 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(24):18267-18271 KOH YC; BUCZKO E; DUFAU ML REQUIREMENT OF PHENYLALANINE-343 FOR THE PREFERENTIAL DELTA-4- LYASE VERSUS DELTA-5-LYASE ACTIVITY OF RAT CYP17	25	12
8696	9	8696 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(26):19463-19470 MAHENDROO MS; MENDELSON CR; SIMPSON ER TISSUE-SPECIFIC AND HORMONALLY CONTROLLED ALTERNATIVE PROMOTERS REGULATE AROMATASE CYTOCHROME-P450 GENE-EXPRESSION IN HUMAN ADIPOSE-TISSUE	165	38
8697	20	8697 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(26):19681-19689 IMAI T; GLOBERMAN H; GERTNER JM; KAGAWA N; WATERMAN MR EXPRESSION AND PURIFICATION OF FUNCTIONAL HUMAN 17-ALPHA- HYDROXYLASE/17,20-LYASE (P450C17) IN ESCHERICHIA-COLI - USE OF THIS SYSTEM FOR STUDY OF A NOVEL FORM OF COMBINED 17-ALPHA- HYDROXYLASE/17,20-LYASE DEFICIENCY	96	46
8698	6	8698 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(28):21399-21402 SHIMOZAWA O; SAKAGUCHI M; OGAWA H; HARADA N; MIHARA K; OMURA T CORE GLYCOSYLATION OF CYTOCHROME-P-450 (AROM) - EVIDENCE FOR LOCALIZATION OF N-TERMINUS OF MICROSOMAL CYTOCHROME-P-450 IN THE LUMEN	37	12
8699	7	8699 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(29):21722-21726 RAMSDEN R; SOMMER KM; OMIECINSKI CJ PHENOBARBITAL INDUCTION AND TISSUE-SPECIFIC EXPRESSION OF THE RAT CYP2B2 GENE IN TRANSGENIC MICE	71	15
8700	18	8700 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(29):21997-22003 STRAUB P; LLOYD M; JOHNSON EF; KEMPER B CASSETTE MUTAGENESIS OF A POTENTIAL SUBSTRATE RECOGNITION REGION OF CYTOCHROME-P450-2C2	34	21

#	Cited nodes	Nodes / Authors	GCS	LCS
8701	7	8701 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(31):23168-23171 STRITTMATTER P; KITTLER JM; COGHILL JE; OZOLS J INTERACTION OF NON-MYRISTOYLATED NADH-CYTOCHROME-B(5) REDUCTASE WITH CYTOCHROME-B(5)-DIMYRISTOYLPHOSPHATIDYLCHOLINE VESICLES	10	1
8702	7	8702 1993 JOURNAL OF CELL BIOLOGY 122(1):265-278 BRISTOW J; TEE MK; GITELMAN SE; MELLON SH; MILLER WL TENASCIN-X - A NOVEL EXTRACELLULAR-MATRIX PROTEIN ENCODED BY THE HUMAN XB GENE OVERLAPPING P450C21B	162	4
8703	6	8703 1993 JOURNAL OF CELL SCIENCE 106():249-259 VERGERES G; YEN TSB; AGGELER J; LAUSIER J; WASKELL L A MODEL SYSTEM FOR STUDYING MEMBRANE BIOGENESIS - OVEREXPRESSION OF CYTOCHROME-B(5) IN YEAST RESULTS IN MARKED PROLIFERATION OF THE INTRACELLULAR MEMBRANE	41	9
8704	11	8704 1993 JOURNAL OF CELLULAR BIOCHEMISTRY 53(3):206-212 TAKAHARA H; ZAIDI SIA; MUKHTAR H; HANDA M; EPSTEIN WL; FUKUYAMA K PURIFICATION AND CHARACTERIZATION OF NADPH-CYTOCHROME P-450 REDUCTASE FROM RAT EPIDERMIS	2	2
8705	3	8705 1993 JOURNAL OF CELLULAR PHYSIOLOGY 156(1):119-129 MAIER P; SCHAWALDER H PHYSIOLOGICAL OXYGEN-TENSION MODULATES THE CHEMICALLY-INDUCED MITOGENIC RESPONSE OF CULTURED RAT HEPATOCYTES	9	0
8706	16	8706 1993 JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY 57(3):195-211 LIVINGSTONE DR BIOTECHNOLOGY AND POLLUTION MONITORING - USE OF MOLECULAR BIOMARKERS IN THE AQUATIC ENVIRONMENT	129	7
8707	2	8707 1993 JOURNAL OF CHROMATOGRAPHY 632(1-2):97-103 CORDIS GA; MAULIK N; BAGCHI D; ENGELMAN RM; DAS DK ESTIMATION OF THE EXTENT OF LIPID-PEROXIDATION IN THE ISCHEMIC AND REPERFUSED HEART BY MONITORING LIPID METABOLIC PRODUCTS WITH THE AID OF HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY	23	2
8708	12	8708 1993 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 76(6):1555-1559 VANVOORHIS BJ; DUNN MS; FALCK JR; BHATT RK; VANROLLINS M; SNYDER GD METABOLISM OF ARACHIDONIC-ACID TO EPOXYEICOSATRIENOIC ACIDS BY HUMAN GRANULOSA-CELLS MAY MEDIATE STEROIDOGENESIS	16	5
8709	3	8709 1993 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 77(1):98-102 SWART P; SWART AC; WATERMAN MR; ESTABROOK RW; MASON JI PROGESTERONE 16-ALPHA-HYDROXYLASE ACTIVITY IS CATALYZED BY HUMAN CYTOCHROME-P450 17-ALPHA-HYDROXYLASE	39	39
8710	11	8710 1993 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 77(2):489-493 FARDELLA CE; ZHANG LH; MAHACHOKLERTWATTANA P; LIN D; MILLER WL DELETION OF AMINO-ACIDS ASP (487)-SER(488)-PHE(489) IN HUMAN CYTOCHROME P450C17 CAUSES SEVERE 17-ALPHA-HYDROXYLASE DEFICIENCY	22	9
8711	7	8711 1993 JOURNAL OF CLINICAL INVESTIGATION 91(6):2488-2496 LEITERSDORF E; RESHEF A; MEINER V; LEVITZKI R; SCHWARTZ SP; DANN EJ; BERKMAN N; CALI JJ; KLAPHOLZ L; BERGINER VM FRAMESHIFT AND SPLICE-JUNCTION MUTATIONS IN THE STEROL 27- HYDROXYLASE GENE CAUSE CEREBROTENDINOUS XANTHOMATOSIS IN JEWS OF MOROCCAN ORIGIN	84	8
8712	19	8712 1993 JOURNAL OF CLINICAL INVESTIGATION 92(2):1018-1024 SCHUETZ JD; KAUMA S; GUZELIAN PS IDENTIFICATION OF THE FETAL LIVER CYTOCHROME-CYP3A7 IN HUMAN ENDOMETRIUM AND PLACENTA	48	23
8713	14	8713 1993 JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 41(1):43-49 WATANABE J; ASAKA Y; FUJIMOTO S; KANAMURA S DENSITIES OF NADPH-FERRIHEMOPROTEIN REDUCTASE AND CYTOCHROME-P- 450 MOLECULES IN THE ENDOPLASMIC-RETICULUM MEMBRANE OF RAT HEPATOCYTES	17	1
8714	8	8714 1993 JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 41(6):877-885 VOIGT JM; GUENGERICH FP; BARON J LOCALIZATION AND INDUCTION OF CYTOCHROME-P450 1A1 AND ARYL- HYDROCARBON HYDROXYLASE-ACTIVITY IN RAT NASAL-MUCOSA	24	3
8715	17	8715 1993 JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 21(6):281-305 BADAWI AF; MOSTAFA MH POSSIBLE MECHANISMS OF ALTERATION IN THE CAPACITIES OF CARCINOGEN METABOLIZING ENZYMES DURING SCHISTOSOMIASIS AND THEIR ROLE IN BLADDER-CANCER INDUCTION	20	0
8716	6	8716 1993 JOURNAL OF INVESTIGATIVE DERMATOLOGY 101(1):59-63 IANNONE A; MARCONI A; ZAMBRUNO G; GIANNETTI A; VANNINI V; TOMASI A FREE-RADICAL PRODUCTION DURING METABOLISM OF ORGANIC HYDROPEROXIDES BY NORMAL HUMAN KERATINOCYTES	12	0
8717	1	8717 1993 JOURNAL OF LABORATORY AND CLINICAL MEDICINE 121(3):372-374 SERHAN CN CELL-CELL INTERACTIONS IN THE GENERATION OF EICOSANOIDS - CHARTING THE ROUTES AND PRODUCTS OF TRANSCELLULAR BIOSYNTHESIS	12	3
8718	12	8718 1993 JOURNAL OF LIPID MEDIATORS 6(1-3):199-208 WONG PYK; LIN KT; YAN YT; AHERN D; ILES J; SHEN SY; BHATT RK; FALCK JR 14(R),15(S)-EPOXYEICOSATRIENOIC ACID (14(R),15(S)-EET) RECEPTOR IN GUINEA-PIG MONONUCLEAR CELL-MEMBRANES	26	15
8719	8	8719 1993 JOURNAL OF LIPID RESEARCH 34(7):1187-1199 KUNDU RK; GETZ GS; TONSGARD JH INDUCTION OF (OMEGA-1)-OXIDATION OF MONOCARBOXYLIC ACIDS BY ACETYLSALICYLIC-ACID	5	2
8720	4	8720 1993 JOURNAL OF MEDICINAL CHEMISTRY 36(10):1418-1424 BURGER A; CLARK JE; NISHIMOTO M; MUERHOFF AS; MASTERS BSS; DEMONTELLANO PRO MECHANISM-BASED INHIBITORS OF PROSTAGLANDIN OMEGA-HYDROXYLASE - (R)-12-HYDROXY-16-HEPTADECYNOIC AND (S)-12-HYDROXY-16- HEPTADECYNOIC ACID AND 2,2-DIMETHYL-12-HYDROXY-16-HEPTADECYNOIC ACID	6	2
8721	7	8721 1993 JOURNAL OF MOLECULAR ENDOCRINOLOGY 10(3):297-311 PESTELL RG; HAMMOND VE; CRAWFORD RJ MOLECULAR-CLONING AND CHARACTERIZATION OF THE CYCLIC AMP- RESPONSIVE OVINE CYP11A1 (CHOLESTEROL SIDE-CHAIN CLEAVAGE) GENE PROMOTER - DNASE-1 PROTECTION OF CONSERVED CONSENSUS ELEMENTS	13	2
8722	9	8722 1993 JOURNAL OF NEUROCHEMISTRY 60(4):1467-1474 KURZ GM; WIESINGER H; HAMPRECHT B PURIFICATION OF CYTOSOLIC MALIC ENZYME FROM BOVINE BRAIN, GENERATION OF MONOCLONAL-ANTIBODIES, AND IMMUNOCYTOCHEMICAL LOCALIZATION OF THE ENZYME IN GLIAL-CELLS OF NEURAL PRIMARY CULTURES	54	3
8723	9	8723 1993 JOURNAL OF NEUROCHEMISTRY 61(1):150-159 AMRUTHESH SC; BOERSCHEL MF; MCKINNEY JS; WILLOUGHBY KA; ELLIS EF METABOLISM OF ARACHIDONIC-ACID TO EPOXYEICOSATRIENOIC ACIDS, HYDROXYEICOSATETRAENOIC ACIDS, AND PROSTAGLANDINS IN CULTURED RAT HIPPOCAMPAL ASTROCYTES	50	11
8724	6	8724 1993 JOURNAL OF NUTRITION 123(2):216-224 MCINTOSH MK; GOLDFARB AH; CURTIS LN; COTE PS VITAMIN-E ALTERS HEPATIC ANTIOXIDANT ENZYMES IN RATS TREATED WITH DEHYDROEPIANDROSTERONE (DHEA)	24	3
8725	6	8725 1993 JOURNAL OF NUTRITIONAL BIOCHEMISTRY 4(5):298-303 MCINTOSH MK; GOLDFARB AH; COTE PS; GRIFFIN K VITAMIN-E REDUCES PEROXISOMAL FATTY-ACID OXIDATION AND INDICATORS OF OXIDATIVE STRESS IN UNTRAINED, EXERCISED RATS TREATED WITH DEHYDROEPIANDROSTERONE (DHEA)	11	0
8726	11	8726 1993 JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS 29(2):77-83 CHIU SHL THE USE OF INVITRO METABOLISM STUDIES IN THE UNDERSTANDING OF NEW DRUGS	25	4
8727	8	8727 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 264(1):89-94 YASUMORI T; CHEN L; NAGATA K; YAMAZOE Y; KATO R SPECIES-DIFFERENCES IN STEREOSELECTIVE METABOLISM OF MEPHENYTOIN BY CYTOCHROME P450 (CYP2C AND CYP3A)	26	11
8728	4	8728 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 264(1):166-171 IMAMURA Y; IWAMOTO K; YANACHI Y; HIGUCHI T; OTAGIRI M POSTNATAL-DEVELOPMENT, SEX-RELATED DIFFERENCE AND HORMONAL- REGULATION OF ACETOHEXAMIDE REDUCTASE ACTIVITIES IN RAT-LIVER AND KIDNEY	23	1
8729	7	8729 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 264(1):457-462 MAINES MD; MAYER RD; EWING JF; MCCOUBREY WK INDUCTION OF KIDNEY HEME OXYGENASE-1 (HSP32) MESSENGER-RNA AND PROTEIN BY ISCHEMIA REPERFUSION - POSSIBLE ROLE OF HEME AS BOTH PROMOTOR OF TISSUE-DAMAGE AND REGULATOR OF HSP32	77	1
8730	13	8730 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 264(2):1012-1020 FERRARI L; JOUZEAU JY; GILLET P; HERBER R; FENER P; BATT AM; NETTER P INTERLEUKIN-1-BETA DIFFERENTIALLY REPRESSES DRUG-METABOLIZING- ENZYMES IN ARTHRITIC FEMALE RATS	10	2
8731	9	8731 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 265(1):281-285 MATHEWS JM; BEND JR N-ARALKYL DERIVATIVES OF 1-AMINOBENZOTRIAZOLE AS POTENT ISOZYME-SELECTIVE MECHANISM-BASED INHIBITORS OF RABBIT PULMONARY CYTOCHROME-P450 INVIVO	11	6
8732	15	8732 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 265(1):401-407 TASSANEEYAKUL W; BIRKETT DJ; VERONESE ME; MCMANUS ME; TUKEY RH; QUATTROCHI LC; GELBOIN HV; MINERS JO SPECIFICITY OF SUBSTRATE AND INHIBITOR PROBES FOR HUMAN CYTOCHROMES-P450 1A1 AND 1A2	186	45
8733	5	8733 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 265(3):1261-1266 OWENS SM; GUNNELL M; LAURENZANA EM; VALENTINE JL DOSE-DEPENDENT AND TIME-DEPENDENT CHANGES IN PHENCYCLIDINE METABOLITE COVALENT BINDING IN RATS AND THE POSSIBLE ROLE OF CYP2D1	16	3
8734	6	8734 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 266(1):52-59 CHIBA K; KOBAYASHI K; MANABE K; TANI M; KAMATAKI T; ISHIZAKI T OXIDATIVE-METABOLISM OF OMEPRAZOLE IN HUMAN LIVER-MICROSOMES - COSEGREGATION WITH S-MEPHENYTOIN 4'-HYDROXYLATION	102	19
8735	38	8735 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 267(2):758-764 KNICKLE LC; WEBB CD; HOUSE AA; BEND JR MECHANISM-BASED INACTIVATION OF CYTOCHROME P450-1A1 BY N- ARALKYL-1-AMINOBENZOTRIAZOLES IN GUINEA-PIG KIDNEY IN-VIVO AND IN-VITRO - MINIMAL EFFECTS ON METABOLISM OF ARACHIDONIC-ACID BY RENAL P450-DEPENDENT MONOOXYGENASES	13	8
8736	17	8736 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 267(2):927-936 KIM HS; PUTT D; REDDY S; HOLLENBERG PF; NOVAK RF ENHANCED EXPRESSION OF RAT HEPATIC CYP2B1/2B2 AND 2E1 BY PYRIDINE - DIFFERENTIAL INDUCTION KINETICS AND MOLECULAR-BASIS OF EXPRESSION	29	7
8737	10	8737 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 267(2):1012-1016 IMAOKA S; WEDLUND PJ; OGAWA H; KIMURA S; GONZALEZ FJ; KIM HY IDENTIFICATION OF CYP2C23 EXPRESSED IN RAT-KIDNEY AS AN ARACHIDONIC-ACID EPOXYGENASE	26	18
8738	3	8738 1993 JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY 17(1):33-40 LISSI EA; ROSENBLUTH H DISRUPTION EFFECTS OF CARBON-TETRACHLORIDE ON RAT-LIVER MICROSOMES	2	0
8739	9	8739 1993 JOURNAL OF REPRODUCTION AND FERTILITY ():77-86 MODE A SEXUALLY DIFFERENTIATED EXPRESSION OF GENES ENCODING THE P4502C CYTOCHROMES IN RAT-LIVER - A MODEL SYSTEM FOR STUDYING THE ACTION OF GROWTH-HORMONE	0	0
8740	13	8740 1993 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 44(1):61-67 MAENPAA J; PELKONEN O; CRESTEIL T; RANE A THE ROLE OF CYTOCHROME-P450 3A (CYP3A) ISOFORM(S) IN OXIDATIVE- METABOLISM OF TESTOSTERONE AND BENZPHETAMINE IN HUMAN ADULT AND FETAL LIVER	31	16
8741	10	8741 1993 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 44(4-6):321-330 SIMPSON ER; MAHENDROO MS; MEANS GD; KILGORE MW; CORBIN CJ; MENDELSON CR TISSUE-SPECIFIC PROMOTERS REGULATE AROMATASE CYTOCHROME-P450 EXPRESSION	47	12
8742	4	8742 1993 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 45(1-3):99-106 ROSLER A; WHITE PC MUTATIONS IN HUMAN 11-BETA-HYDROXYLASE GENES - 11-BETA- HYDROXYLASE DEFICIENCY IN JEWS OF MOROCCO AND CORTICOSTERONE METHYL-OXIDASE-II DEFICIENCY IN JEWS OF IRAN	10	2
8743	7	8743 1993 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 46(3):321-329 MILEWICH L; MARRERO M; TEZABWALA BU; BENNETT M; FRENKEL RA; SLAUGHTER CA INDUCTION OF MURINE HEPATIC GLUTATHIONE-S-TRANSFERASE BY DIETARY DEHYDROEPIANDROSTERONE	3	1
8744	1	8744 1993 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 46(4):451-462 COPLAND JA; HENDRY LB; CHU CK; WOOD JC; WRENN RW; PANTAZIS CG; MAHESH VB INHIBITION OF ESTROGEN-STIMULATED MITOGENESIS BY 3- PHENYLACETYLAMINO-2,6-PIPERIDINEDIONE AND ITS PARA-HYDROXY ANALOG	9	0
8745	5	8745 1993 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 47(1-6):191-194 WARNER M; STROMSTEDT M; WYSS A; GUSTAFSSON JA REGULATION OF CYTOCHROME-P450 IN THE CENTRAL-NERVOUS-SYSTEM	25	6
8746	1	8746 1993 JOURNAL OF SURGICAL RESEARCH 55(6):575-580 OBITABOT ET; HANRAHAN LM; CACHECHO R; BEER ER; HOPKINS SR; CHAN JCK; SHAPIRO JM; LAMORTE WW CHANGES IN HEPATOCYTE NADH FLUORESCENCE DURING PROLONGED HYPOXIA	15	0
8747	2	8747 1993 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 115(1):218-223 HALPERN HJ; POU S; PERIC M; YU C; BARTH E; ROSEN GM DETECTION AND IMAGING OF OXYGEN-CENTERED FREE-RADICALS WITH LOW-FREQUENCY ELECTRON-PARAMAGNETIC RESONANCE AND SIGNAL- ENHANCING DEUTERIUM-CONTAINING SPIN TRAPS	19	1
8748	1	8748 1993 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 115(19):8775-8779 HARRIS D; LOEW G DETERMINANTS OF THE SPIN-STATE OF THE RESTING STATE OF CYTOCHROME-P450CAM	41	5
8749	9	8749 1993 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 3(8):1496-1500 TAKAHASHI K; HARRIS RC; CAPDEVILA JH; KARARA A; MAKITA K; JACOBSON HR; MUNGER KA; BADR KF INDUCTION OF RENAL ARACHIDONATE CYTOCHROME-P-450 EPOXYGENASE AFTER UNINEPHRECTOMY - COUNTERREGULATION OF HYPERFILTRATION	10	3
8750	2	8750 1993 JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2 (11):2113-2117 PINHEIRO TJT; BRATT PJ; DAVIS IH; DOETSCHMAN DC; WATTS A SPIN-LATTICE RELAXATION-TIMES OF PHOSPHOLIPID AMINOXYL SPIN LABELS IN CARDIOLIPIN CYTOCHROME-C BILAYERS - A PULSE SATURATION RECOVERY EPR STUDY	2	0
8751	6	8751 1993 JOURNAL OF THE NATIONAL CANCER INSTITUTE 85(23):1888-1891 NEBERT DW ELEVATED ESTROGEN 16-ALPHA-HYDROXYLASE ACTIVITY - IS THIS A GENOTOXIC OR NONGENOTOXIC BIOMARKER IN HUMAN BREAST-CANCER RISK	20	4
8752	16	8752 1993 JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY 105(3):541-549 NING XH; DING XX; CHILDS KF; BOLLING SF; GALLAGHER KP FLAVONE IMPROVES FUNCTIONAL RECOVERY AFTER ISCHEMIA IN ISOLATED REPERFUSED RABBIT HEARTS	7	0
8753	10	8753 1993 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 38(1):43-55 ZANGAR RC; SPRINGER DL; BUHLER DR ALTERATIONS IN CYTOCHROME-P-450 LEVELS IN ADULT-RATS FOLLOWING NEONATAL EXPOSURE TO XENOBIOTICS	13	4
8754	11	8754 1993 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 40(2-3):177-194 SIDHU JS; KAVANAGH TJ; REILLY MT; OMIECINSKI CJ DIRECT DETERMINATION OF FUNCTIONAL-ACTIVITY OF CYTOCHROME-P- 4501A1 AND NADPH DT-DIAPHORASE IN HEPATOMA-CELL LINES USING NONINVASIVE SCANNING LASER CYTOMETRY	14	3
8755	9	8755 1993 JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY 31(1):173-196 BRENT JA; RUMACK BH ROLE OF FREE-RADICALS IN TOXIC HEPATIC-INJURY .2. ARE FREE- RADICALS THE CAUSE OF TOXIN-INDUCED LIVER-INJURY	31	0
8756	4	8756 1993 JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 16(1):106-109 GALTIER P; KADDOURI M; EECKHOUTTE C COMPARED N-DEMETHYLATION OF VETERINARY DRUGS BY MICROSOMES FROM NORMAL AND FLUKE-INFECTED SHEEP LIVERS	4	0
8757	7	8757 1993 JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 16(2):152-163 ELTOM SE; BABISH JG; SCHWARK WS THE POSTNATAL-DEVELOPMENT OF DRUG-METABOLIZING-ENZYMES IN HEPATIC, PULMONARY AND RENAL TISSUES OF THE GOAT	8	1
8758	8	8758 1993 LIFE SCIENCES 52(1):29-34 LEEMANN T; TRANSON C; DAYER P CYTOCHROME-P450TB (CYP2C) - A MAJOR MONOOXYGENASE CATALYZING DICLOFENAC 4'-HYDROXYLATION IN HUMAN LIVER	131	30
8759	5	8759 1993 LIFE SCIENCES 52(10):PL91-PL96 TRIVIER JM; LIBERSA C; BELLOC C; LHERMITTE M AMIODARONE N-DEETHYLATION IN HUMAN LIVER-MICROSOMES - INVOLVEMENT OF CYTOCHROME-P450-3A ENZYMES .1.	4	1
8760	5	8760 1993 LIFE SCIENCES 52(21):1709-1716 RAO MS; IDE H; ALVARES K; SUBBARAO V; REDDY JK; HECHTER O; YELDANDI AV COMPARATIVE EFFECTS OF DEHYDROEPIANDROSTERONE AND RELATED STEROIDS ON PEROXISOME PROLIFERATION IN RAT-LIVER	12	3
8761	2	8761 1993 LIFE SCIENCES 53(14):1137-1147 CAVALLARO S; PANI L; GUIDOTTI A; COSTA E ACTH-INDUCED MITOCHONDRIAL DBI RECEPTOR (MDR) AND DIAZEPAM- BINDING INHIBITOR (DBI) EXPRESSION IN ADRENALS OF HYPOPHYSECTOMIZED RATS IS NOT CAUSE-EFFECT RELATED TO ITS IMMEDIATE STEROIDOGENIC ACTION	7	1
8762	7	8762 1993 MAGNETIC RESONANCE IN CHEMISTRY 31():S47-S52 CHMIELEWSKI PJ; LATOSGRAZYNSKI L; RACHLEWICZ K H-1 NUCLEAR-MAGNETIC-RESONANCE STUDIES OF THE REACTION OF IRON(III) PORPHYRIN CATION-RADICAL WITH ARYL GRIGNARD-REAGENTS	4	0
8763	6	8763 1993 MARINE ECOLOGY-PROGRESS SERIES 97(3):309-316 BURGEOT T; BOCQUENE G; TRUQUET P; LEDEAN L; POULARD JC; DOREL D; SOUPLET A; GALGANI F THE DRAGONET CALLIONYMUS-LYRA, A TARGET SPECIES USED FOR EVALUATION OF BIOLOGICAL EFFECTS OF CHEMICAL CONTAMINANTS ON FRENCH COASTS	3	0
8764	4	8764 1993 METALLOBIOCHEMISTRY, PART C 226():97-118 CHANCE MR LOW-TEMPERATURE OPTICAL SPECTROSCOPY - METALLOPROTEIN STRUCTURE AND DYNAMICS	6	0
8765	4	8765 1993 METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY 15(10):715-719 TANTCHEVA L; STOYTCHEV T; MEHANDJIEVA E; TIVCHEVA L LIVER AND KIDNEY MONOOXYGENASE ACTIVITY IN RATS SUBCHRONICALLY TREATED WITH ZN AND PB SALTS AND THEIR COMBINATION	0	0
8766	2	8766 1993 MOLECULAR AND CELLULAR BIOCHEMISTRY 120(1):1-13 AON MA; CORTASSA S AN ALLOMETRIC INTERPRETATION OF THE SPATIOTEMPORAL ORGANIZATION OF MOLECULAR AND CELLULAR PROCESSES	4	1
8767	3	8767 1993 MOLECULAR AND CELLULAR BIOCHEMISTRY 126(1):69-75 MUKHOPADHYAY M; MUKHOPADHYAY CK; CHATTERJEE IB PROTECTIVE EFFECT OF ASCORBIC-ACID AGAINST LIPID-PEROXIDATION AND OXIDATIVE DAMAGE IN CARDIAC-MICROSOMES	12	0
8768	9	8768 1993 MOLECULAR AND CELLULAR ENDOCRINOLOGY 91(1-2):201-209 OERTLE M; MULLER J 2 TYPES OF CYTOCHROME-P-45011-BETA IN RAT ADRENALS - SEPARATE REGULATION OF GENE-EXPRESSION	27	3
8769	7	8769 1993 MOLECULAR AND CELLULAR ENDOCRINOLOGY 93(1):1-10 LEHOUX JG; DUCHARME L EFFECTS OF DEXAMETHASONE ON THE LEVELS OF ADRENAL STEROIDOGENIC ENZYME MESSENGER-RNA IN RATS TREATED WITH 4- AMINOPYRAZOLOPYRIMIDINE	3	0
8770	4	8770 1993 MOLECULAR AND CELLULAR ENDOCRINOLOGY 94(2):R9-R13 HOLLAND OB; MATHIS JM; BIRD IM; RAINEY WE ANGIOTENSIN INCREASES ALDOSTERONE SYNTHASE MESSENGER-RNA LEVELS IN HUMAN NCI-H295 CELLS	23	3
8771	7	8771 1993 MOLECULAR AND CELLULAR ENDOCRINOLOGY 94(2):235-242 LAUBER ME; PICTON HM; BEGEOT M; MOMOI K; WATERMAN MR; SIMPSON ER REGULATION OF CYP11A GENE-EXPRESSION IN BOVINE OVARIAN GRANULOSA-CELLS IN PRIMARY CULTURE BY CAMP AND PHORBOL ESTERS IS CONFERRED BY A COMMON CIS-ACTING ELEMENT	12	2
8772	9	8772 1993 MOLECULAR AND CELLULAR ENDOCRINOLOGY 97(1-2):R1-R6 JENKINS C; MICHAEL D; MAHENDROO M; SIMPSON E EXON-SPECIFIC NORTHERN ANALYSIS AND RAPID AMPLIFICATION OF CDNA ENDS (RACE) REVEAL THAT THE PROXIMAL PROMOTER-II (PII) IS RESPONSIBLE FOR AROMATASE CYTOCHROME-P-450 (CYP19) EXPRESSION IN HUMAN OVARY	28	14
8773	12	8773 1993 MOLECULAR CARCINOGENESIS 7(4):268-275 CAMUS AM; GENESTE O; HONKAKOSKI P; BEREZIAT JC; HENDERSON CJ; WOLF CR; BARTSCH H; LANG MA HIGH VARIABILITY OF NITROSAMINE METABOLISM AMONG INDIVIDUALS - ROLE OF CYTOCHROMES P450 2A6 AND 2E1 IN THE DEALKYLATION OF N- NITROSODIMETHYLAMINE AND N-NITROSODIETHYLAMINE IN MICE AND HUMANS	85	18
8774	11	8774 1993 MOLECULAR CARCINOGENESIS 7(4):276-280 KOBLIAKOV V; KULIKOVA L; SAMOILOV D; LANG MA HIGH EXPRESSION OF CYTOCHROME-P450 2A-5 (COUMARIN 7- HYDROXYLASE) IN MOUSE HEPATOMAS	15	6
8775	11	8775 1993 MOLECULAR ENDOCRINOLOGY 7(2):206-213 TRZECIAK WH; LEHOUX JG; WATERMAN MR; SIMPSON ER DEXAMETHASONE INHIBITS CORTICOTROPIN-INDUCED ACCUMULATION OF CYP11A AND CYP17 MESSENGER-RNAS IN BOVINE ADRENOCORTICAL-CELLS	17	1
8776	7	8776 1993 MOLECULAR ENDOCRINOLOGY 7(2):283-290 PARISSENTI AM; PARKER KL; SCHIMMER BP IDENTIFICATION OF PROMOTER ELEMENTS IN THE MOUSE 21-HYDROXYLASE (CYP21) GENE THAT REQUIRE A FUNCTIONAL CYCLIC ADENOSINE 3',5'- MONOPHOSPHATE-DEPENDENT PROTEIN-KINASE	29	6
8777	3	8777 1993 MOLECULAR ENDOCRINOLOGY 7(3):453-461 ROGLER LE; PINTAR JE EXPRESSION OF THE P450 SIDE-CHAIN CLEAVAGE AND ADRENODOXIN GENES BEGINS DURING EARLY STAGES OF ADRENAL-CORTEX DEVELOPMENT	23	1
8778	7	8778 1993 MOLECULAR ENDOCRINOLOGY 7(12):1617-1624 AMARNEH B; CORBIN CJ; PETERSON JA; SIMPSON ER; GRAHAMLORENCE S FUNCTIONAL DOMAINS OF HUMAN AROMATASE CYTOCHROME-P450 CHARACTERIZED BY LINEAR ALIGNMENT AND SITE-DIRECTED MUTAGENESIS	31	8
8779	1	8779 1993 MOLECULAR PHARMACOLOGY 43(2):139-148 MOEBIUS FF; BURROWS GG; STRIESSNIG J; GLOSSMANN H BIOCHEMICAL-CHARACTERIZATION OF A 22-KDA HIGH-AFFINITY ANTIISCHEMIC DRUG-BINDING POLYPEPTIDE IN THE ENDOPLASMIC- RETICULUM OF GUINEA-PIG LIVER - POTENTIAL COMMON TARGET FOR ANTIISCHEMIC DRUG-ACTION	26	0
8780	15	8780 1993 MOLECULAR PHARMACOLOGY 43(2):183-190 OHMORI S; SHIRAKAWA C; MOTOHASHI K; YOSHIDA H; ABE H; NAKAMURA T; HORIE T; KITAGAWA H; ASAOKA K; RIKIHISA T; KANAKUBO O; KITADA M PURIFICATION FROM LIVER-MICROSOMES FROM UNTREATED CYNOMOLGUS MONKEYS OF CYTOCHROME P450 CLOSELY RELATED TO HUMAN CYTOCHROME P450 2B6	26	14
8781	12	8781 1993 MOLECULAR PHARMACOLOGY 43(4):504-508 QUATTROCHI LC; TUKEY RH NUCLEAR UPTAKE OF THE AH (DIOXIN) RECEPTOR IN RESPONSE TO OMEPRAZOLE - TRANSCRIPTIONAL ACTIVATION OF THE HUMAN CYP1A1 GENE	43	7
8782	1	8782 1993 MOLECULAR PHARMACOLOGY 43(6):878-887 HONCHEL R; AKSOY IA; SZUMLANSKI C; WOOD TC; OTTERNESS DM; WIEBEN ED; WEINSHILBOUM RM HUMAN THIOPURINE METHYLTRANSFERASE - MOLECULAR-CLONING AND EXPRESSION OF T84 COLON-CARCINOMA CELL CDNA	51	6
8783	5	8783 1993 MOLECULAR PHARMACOLOGY 44(1):216-221 NAKASA H; KOMIYA M; OHMORI S; RIKIHISA T; KIUCHI M; KITADA M CHARACTERIZATION OF HUMAN LIVER MICROSOMAL CYTOCHROME-P450 INVOLVED IN THE REDUCTIVE METABOLISM OF ZONISAMIDE	30	9
8784	7	8784 1993 MOLECULAR PHARMACOLOGY 44(3):560-568 STERLING K; WEAVER J; HO KL; XU LC; BRESNICK E RAT CYP1A1 NEGATIVE REGULATORY ELEMENT - BIOLOGICAL-ACTIVITY AND INTERACTION WITH A PROTEIN FROM LIVER AND HEPATOMA-CELLS	36	12
8785	10	8785 1993 MOLECULAR PHARMACOLOGY 44(4):775-783 SHAW PM; ADESNIK M; WEISS MC; CORCOS L THE PHENOBARBITAL-INDUCED TRANSCRIPTIONAL ACTIVATION OF CYTOCHROME-P-450 GENES IS BLOCKED BY THE GLUCOCORTICOID- PROGESTERONE ANTAGONIST RU486	40	12
8786	3	8786 1993 MOLECULAR PHARMACOLOGY 44(6):1142-1151 CANGA L; PAROLI L; BLANCK TJJ; SILVER RB; RIFKIND AB 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN INCREASES CARDIAC MYOCYTE INTRACELLULAR CALCIUM AND PROGRESSIVELY IMPAIRS VENTRICULAR CONTRACTILE RESPONSES TO ISOPROTERENOL AND TO CALCIUM IN CHICK- EMBRYO HEARTS	19	6
8787	1	8787 1993 MUTATION RESEARCH 286(1):111-118 TENNANT RW STRATIFICATION OF RODENT CARCINOGENICITY BIOASSAY RESULTS TO REFLECT RELATIVE HUMAN HAZARD	52	0
8788	11	8788 1993 MUTATION RESEARCH 290(1):27-33 MCKINNON RA; BURGESS WM; GONZALEZ FJ; MCMANUS ME METABOLIC DIFFERENCES IN COLON MUCOSAL CELLS	13	6
8789	26	8789 1993 MUTATION RESEARCH 295(4-6):201-222 MANJGALADZE M; CHEN S; FRAME LT; SENG JE; DUFFY PH; FEUERS RJ; HART RW; LEAKEY JEA EFFECTS OF CALORIC RESTRICTION ON RODENT DRUG AND CARCINOGEN METABOLIZING ENZYMES - IMPLICATIONS FOR MUTAGENESIS AND CANCER	37	4
8790	6	8790 1993 MUTATION RESEARCH 295(4-6):223-235 CHOU MW; KONG J; CHUNG KT; HART RW EFFECT OF CALORIC RESTRICTION ON THE METABOLIC-ACTIVATION OF XENOBIOTICS	21	2
8791	4	8791 1993 NATURE 366(6452):276-279 HOLTON TA; BRUGLIERA F; LESTER DR; TANAKA Y; HYLAND CD; MENTING JGT; LU CY; FARCY E; STEVENSON TW; CORNISH EC CLONING AND EXPRESSION OF CYTOCHROME-P450 GENES-CONTROLLING FLOWER COLOR	118	45
8792	2	8792 1993 NEUROLOGY 43(5):884-890 MATTHEWS PM; FORD B; DANDURAND RJ; EIDELMAN DH; OCONNOR D; SHERWIN A; KARPATI G; ANDERMANN F; ARNOLD DL COENZYME-Q(10) WITH MULTIPLE VITAMINS IS GENERALLY INEFFECTIVE IN TREATMENT OF MITOCHONDRIAL DISEASE	59	2
8793	5	8793 1993 NEURON 11(4):633-644 FRASER DD; HOEHN K; WEISS S; MACVICAR BA ARACHIDONIC-ACID INHIBITS SODIUM CURRENTS AND SYNAPTIC TRANSMISSION IN CULTURED STRIATAL NEURONS	58	1
8794	16	8794 1993 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 46(1):15-26 ADAMS NH; LEVI PE; HODGSON E DIFFERENCES IN INDUCTION OF 3 P450 ISOZYMES BY PIPERONYL BUTOXIDE, SESAMEX, SAFROLE, AND ISOSAFROLE	12	4
8795	6	8795 1993 PHARMACEUTICAL RESEARCH 10(1):35-43 ADEDOYIN A; AARONS L; HOUSTON JB TIME-DEPENDENT DISPOSITION OF BETA-NAPHTHOFLAVONE IN THE RAT	3	0
8796	28	8796 1993 PHARMACOGENETICS 3(1):1-18 KORZEKWA KR; JONES JP PREDICTING THE CYTOCHROME-P450 MEDIATED METABOLISM OF XENOBIOTICS	79	35
8797	7	8797 1993 PHARMACOGENETICS 3(1):19-27 HIRVONEN A; HUSGAFVELPURSIAINEN K; ANTTILA S; KARJALAINEN A; PELKONEN O; VAINIO H PCR-BASED CYP2D6 GENOTYPING FOR FINNISH LUNG-CANCER PATIENTS	54	4
8798	3	8798 1993 PHARMACOGENETICS 3(1):40-44 LAWTON MP; PHILPOT RM MOLECULAR-GENETICS OF THE FLAVIN-DEPENDENT MONOOXYGENASES	17	8
8799	12	8799 1993 PHARMACOGENETICS 3(2):77-85 CHEN LS; YASUMORI T; YAMAZOE Y; KATO R HEPATIC-MICROSOMAL TOLBUTAMIDE HYDROXYLATION IN JAPANESE - INVITRO EVIDENCE FOR RAPID AND SLOW METABOLIZERS	13	7
8800	9	8800 1993 PHARMACOGENETICS 3(3):123-130 BROLY F; MEYER UA DEBRISOQUINE OXIDATION POLYMORPHISM - PHENOTYPIC CONSEQUENCES OF A 3-BASE-PAIR DELETION IN EXON 5 OF THE CYP2D6 GENE	35	7

#	Cited nodes	Nodes / Authors	GCS	LCS
8801	8	8801 1993 PHARMACOGENETICS 3(4):167-181 SISK SC; PEARSON WR DIFFERENCES IN INDUCTION BY XENOBIOTICS IN MURINE TISSUES AND THE HEPA1C1C7 CELL-LINE OF MESSENGER-RNAS ENCODING GLUTATHIONE TRANSFERASE, QUINONE REDUCTASE, AND CYP1A P450S	3	0
8802	20	8802 1993 PHARMACOGENETICS 3(5):213-230 SWANSON HI; BRADFIELD CA THE AH-RECEPTOR - GENETICS, STRUCTURE AND FUNCTION	274	32
8803	14	8803 1993 PHARMACOGENETICS 3(5):239-249 SCHWEIKL H; TAYLOR JA; KITAREEWAN S; LINKO P; NAGORNEY D; GOLDSTEIN JA EXPRESSION OF CYP1A1 AND CYP1A2 GENES IN HUMAN LIVER	69	16
8804	4	8804 1993 PHARMACOGENETICS 3(6):281-290 VASILIOU V; REUTER SF; KOZAK CA; NEBERT DW MOUSE DIOXIN-INDUCIBLE CYTOSOLIC ALDEHYDE DEHYDROGENASE-3 - AHD4 CDNA SEQUENCE, GENETIC-MAPPING, AND DIFFERENCES IN MESSENGERRNA LEVELS	29	2
8805	15	8805 1993 PHARMACOGENETICS 3(6):291-301 YASUMORI T; NAGATA K; YANG SK; CHEN LS; MURAYAMA N; YAMAZOE Y; KATO R CYTOCHROME-P450 MEDIATED METABOLISM OF DIAZEPAM IN HUMAN AND RAT - INVOLVEMENT OF HUMAN CYP2C IN N-DEMETHYLATION IN THE SUBSTRATE CONCENTRATION-DEPENDENT MANNER	69	27
8806	5	8806 1993 PHARMACOLOGICAL RESEARCH 28(3):243-248 HORSMANS Y; DESAGER JP; VANDENBERGE V; ABRASSART M; HARVENGT C EFFECTS OF SIMVASTATIN AND PRAVASTATIN ON 6-BETA- HYDROXYCORTISOL EXCRETION, A POTENTIAL MARKER OF CYTOCHROME-P- 450-3A	18	3
8807	27	8807 1993 PHARMACOLOGICAL REVIEWS 45(4):413-453 GELBOIN HV CYTOCHROME-P450 AND MONOCLONAL-ANTIBODIES	58	22
8808	1	8808 1993 PHARMACOLOGY 46(5):294-300 LEDUC BW; SINCLAIR PR; SHUSTER L; SINCLAIR JF; EVANS JE; GREENBLATT DJ NORCOCAINE AND N-HYDROXYNORCOCAINE FORMATION IN HUMAN LIVER- MICROSOMES - ROLE OF CYTOCHROME-P-450-3A4	30	10
8809	24	8809 1993 PHARMACOLOGY & THERAPEUTICS 57(2-3):237-257 MARTUCCI CP; FISHMAN J P450 ENZYMES OF ESTROGEN METABOLISM	162	15
8810	33	8810 1993 PHARMACOLOGY & THERAPEUTICS 57(2-3):291-345 CHRISTIANS U; SEWING KF CYCLOSPORINE METABOLISM IN TRANSPLANT PATIENTS	74	2
8811	3	8811 1993 PHARMACOLOGY & THERAPEUTICS 58(1):67-91 QUIROGA J; PRIETO J LIVER CYTOPROTECTION BY PROSTAGLANDINS	67	3
8812	13	8812 1993 PHARMACOLOGY & THERAPEUTICS 58(2):133-155 GUT J; CHRISTEN U; HUWYLER J MECHANISMS OF HALOTHANE TOXICITY - NOVEL INSIGHTS	58	6
8813	39	8813 1993 PHARMACOLOGY & THERAPEUTICS 58(3):301-317 KEENEY DS; WATERMAN MR REGULATION OF STEROID HYDROXYLASE GENE-EXPRESSION - IMPORTANCE TO PHYSIOLOGY AND DISEASE	23	10
8814	8	8814 1993 PHARMACOLOGY & THERAPEUTICS 60(1):1-38 KRAHENBUHL S ALTERATIONS IN MITOCHONDRIAL-FUNCTION AND MORPHOLOGY IN CHRONIC LIVER-DISEASE - PATHOGENESIS AND POTENTIAL FOR THERAPEUTIC INTERVENTION	12	0
8815	22	8815 1993 PHARMACOLOGY & THERAPEUTICS 60(3):461-500 SEATON MJ; VESELL ES VARIABLES AFFECTING NICOTINE METABOLISM	8	0
8816	6	8816 1993 PHARMACOLOGY & TOXICOLOGY 72():36-47 BOND JA METABOLISM AND ELIMINATION OF INHALED DRUGS AND AIRBORNE CHEMICALS FROM THE LUNGS	4	0
8817	11	8817 1993 PHARMACOLOGY & TOXICOLOGY 72(2):107-112 HONKAKOSKI P; MAENPAA J; LEIKOLA J; PASANEN M; JUVONEN R; LANG MA; PELKONEN O; RAUNIO H CYTOCHROME P4502A-MEDIATED COUMARIN 7-HYDROXYLATION AND TESTOSTERONE HYDROXYLATION IN MOUSE AND RAT LUNG	22	10
8818	15	8818 1993 PHARMACOLOGY & TOXICOLOGY 73(6):319-324 BJELOGRLIC N; PENG RX; PARK SS; GELBOIN HV; HONKAKOSKI P; PELKONEN O; VAHAKANGAS K INVOLVEMENT OF P450 1A1 IN BENZO(A)PYRENE BUT NOT IN BENZO(A)PYRENE-7,8-DIHYDRODIOL ACTIVATION BY 3- METHYLCHOLANTHRENE-INDUCED MOUSE-LIVER MICROSOMES	6	0
8819	1	8819 1993 PHARMAZIE 48(8):626-627 MERKEL U; SIGUSCH H; HOFFMANN A EXCRETION OF 7-HYDROXYCOUMARIN CONJUGATES IN HUMAN URINE	0	0
8820	5	8820 1993 PHYSIOLOGICAL REVIEWS 73(3):547-582 SCHARFF O; FODER B REGULATION OF CYTOSOLIC CALCIUM IN BLOOD-CELLS	49	0
8821	2	8821 1993 PHYTOCHEMISTRY 32(1):79-86 GERARDY R; ZENK MH FORMATION OF SALUTARIDINE FROM (R)-RETICULINE BY A MEMBRANE- BOUND CYTOCHROME-P-450 ENZYME FROM PAPAVER-SOMNIFERUM	44	9
8822	2	8822 1993 PHYTOCHEMISTRY 32(3):653-657 CLEMENS S; HINDERER W; WITTKAMPF U; BARZ W CHARACTERIZATION OF CYTOCHROME P450-DEPENDENT ISOFLAVONE HYDROXYLASES FROM CHICKPEA	20	7
8823	5	8823 1993 PLANT MOLECULAR BIOLOGY 23(5):933-946 TOGURI T; UMEMOTO N; KOBAYASHI O; OHTANI T ACTIVATION OF ANTHOCYANIN SYNTHESIS GENES BY WHITE-LIGHT IN EGGPLANT HYPOCOTYL TISSUES, AND IDENTIFICATION OF AN INDUCIBLE P-450 CDNA	37	12
8824	4	8824 1993 PLANT SCIENCE 94(1-2):119-126 TOGURI T; AZUMA M; OHTANI T THE CLONING AND CHARACTERIZATION OF A CDNA-ENCODING A CYTOCHROME-P450 FROM THE FLOWERS OF PETUNIA-HYBRIDA	11	9
8825	14	8825 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(7):2651-2655 PERNECKY SJ; LARSON JR; PHILPOT RM; COON MJ EXPRESSION OF TRUNCATED FORMS OF LIVER MICROSOMAL P450 CYTOCHROMES 2B4 AND 2E1 IN ESCHERICHIA-COLI - INFLUENCE OF NH2- TERMINAL REGION ON LOCALIZATION IN CYTOSOL AND MEMBRANES	59	30
8826	3	8826 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(7):2890-2894 SHET MS; SATHASIVAN K; ARLOTTO MA; MEHDY MC; ESTABROOK RW PURIFICATION, CHARACTERIZATION, AND CDNA CLONING OF AN NADPH- CYTOCHROME-P450 REDUCTASE FROM MUNG BEAN	34	34
8827	1	8827 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(8):3715-3719 LANCET D; SADOVSKY E; SEIDEMANN E PROBABILITY MODEL FOR MOLECULAR RECOGNITION IN BIOLOGICAL RECEPTOR REPERTOIRES - SIGNIFICANCE TO THE OLFACTORY SYSTEM	57	4
8828	7	8828 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(9):4047-4051 KERSTING U; KERSTING D; SPRING KR KETOCONAZOLE ACTIVATES CL- CONDUCTANCE AND BLOCKS CL- AND FLUID ABSORPTION BY CULTURED CYSTIC-FIBROSIS (CFPAC-1) CELLS	24	3
8829	10	8829 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(9):4102-4106 TEUTSCH HG; HASENFRATZ MP; LESOT A; STOLTZ C; GARNIER JM; JELTSCH JM; DURST F; WERCKREICHHART D ISOLATION AND SEQUENCE OF A CDNA-ENCODING THE JERUSALEM- ARTICHOKE CINNAMATE 4-HYDROXYLASE, A MAJOR PLANT CYTOCHROME- P450 INVOLVED IN THE GENERAL PHENYLPROPANOID PATHWAY	91	36
8830	6	8830 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(10):4552-4556 CURNOW KM; SLUTSKER L; VITEK J; COLE T; SPEISER PW; NEW MI; WHITE PC; PASCOE L MUTATIONS IN THE CYP11B1 GENE CAUSING CONGENITAL ADRENAL- HYPERPLASIA AND HYPERTENSION CLUSTER IN EXON-6, EXON-7, AND EXON-8	78	19
8831	3	8831 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(18):8668-8672 GUO YD; STRUGNELL S; BACK DW; JONES G TRANSFECTED HUMAN LIVER CYTOCHROME-P-450 HYDROXYLATES VITAMIN-D ANALOGS AT DIFFERENT SIDE-CHAIN POSITIONS	47	9
8832	6	8832 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(24):11483-11487 SHEN ZY; WELLS RL; LIU JM; ELKIND MM IDENTIFICATION OF A CYTOCHROME-P450 GENE BY REVERSE TRANSCRIPTION-PCR USING DEGENERATE PRIMERS CONTAINING INOSINE	20	9
8833	10	8833 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(24):11673-11677 ITO Y; FISHER CR; CONTE FA; GRUMBACH MM; SIMPSON ER MOLECULAR-BASIS OF AROMATASE DEFICIENCY IN AN ADULT FEMALE WITH SEXUAL INFANTILISM AND POLYCYSTIC OVARIES	76	11
8834	19	8834 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(24):11748-11752 SHET MS; FISHER CW; HOLMANS PL; ESTABROOK RW HUMAN CYTOCHROME-P450-3A4 - ENZYMATIC-PROPERTIES OF A PURIFIED RECOMBINANT FUSION PROTEIN CONTAINING NADPH-P450 REDUCTASE	87	87
8835	9	8835 1993 PROGRESS IN LIPID RESEARCH 32(4):357-416 MERCER EI INHIBITORS OF STEROL BIOSYNTHESIS AND THEIR APPLICATIONS	45	3
8836	2	8836 1993 PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS 48(1):79-87 BOONE DL; CURRIE WD; LEUNG PCK ARACHIDONIC-ACID AND CELL SIGNALING IN THE OVARY AND PLACENTA	21	1
8837	2	8837 1993 PSYCHIATRIC CLINICS OF NORTH AMERICA 16(3):647-671 CALLAHAN AM; FAVA M; ROSENBAUM JF DRUG-INTERACTIONS IN PSYCHOPHARMACOLOGY	17	0
8838	2	8838 1993 RAPID COMMUNICATIONS IN MASS SPECTROMETRY 7(7):605-609 MACRAE PV; JONES BC; TODD JFJ INVESTIGATION OF THE METABOLISM OF FELODIPINE USING ONLINE LIQUID-CHROMATOGRAPHY UV DIODE-ARRAY DETECTION ATMOSPHERIC- PRESSURE CHEMICAL-IONIZATION MASS-SPECTROMETRY AS A DIAGNOSTIC- TOOL	6	0
8839	4	8839 1993 RECUEIL DES TRAVAUX CHIMIQUES DES PAYS-BAS-JOURNAL OF THE ROYAL NETHERLANDS CHEMICAL SOCIETY 112(2):186-190 KOYMANS LMH; MENGE WMPB; VANLENTHE JH; DENKELDER GMDO; TEKOPPELE JM; VERMEULEN NPE A THEORETICAL-STUDY ON THE OXIDATIVE-METABOLISM OF 4- CHLOROACETANILIDE BY CYTOCHROME-P450 - ALTERNATIVE MECHANISMS FOR MIGRATION OF 4-SUBSTITUENTS DURING ENZYMATIC OXIDATION	1	0
8840	4	8840 1993 RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY 80(3):375-378 TANI E; KOUROUNAKIS PN ACTION OF OXATOMIDE ON THE HEPATIC-MICROSOMAL ENZYME-SYSTEM - EFFECT OF THE MONOOXYGENASE AND PEROXIDASE-ACTIVITY OF P-450 ON DRUG N-DEMETHYLATIONS	0	0
8841	3	8841 1993 SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY 28(11):958-962 TOBI M; DARMON E; ROZEN P; AVIGDOR S; RATTAN J; SANTO M; BARNEA ER LARGE-BOWEL MUCOSAL BIOTRANSFORMATION ACTIVITY IN PERSONS AT HIGH-RISK FOR COLORECTAL-CANCER - A PRELIMINARY-REPORT	5	0
8842	12	8842 1993 SCIENCE 261(5122):731-736 RAVICHANDRAN KG; BODDUPALLI SS; HASEMANN CA; PETERSON JA; DEISENHOFER J CRYSTAL-STRUCTURE OF HEMOPROTEIN DOMAIN OF P450BM-3, A PROTOTYPE FOR MICROSOMAL P450S	547	252
8843	21	8843 1993 STEROIDS 58(12):573-579 MCGIFF JC; QUILLEY CP; CARROLL MA THE CONTRIBUTION OF CYTOCHROME P450-DEPENDENT ARACHIDONATE METABOLITES TO INTEGRATED RENAL-FUNCTION	17	7
8844	8	8844 1993 THERAPEUTIC DRUG MONITORING 15(1):11-17 SINDRUP SH; BROSEN K; HANSEN MGJ; AAESJORGENSEN T; OVERO KF; GRAM LF PHARMACOKINETICS OF CITALOPRAM IN RELATION TO THE SPARTEINE AND THE MEPHENYTOIN OXIDATION POLYMORPHISMS	106	18
8845	5	8845 1993 THERAPEUTIC DRUG MONITORING 15(1):18-24 GRAM LF; HANSEN MGJ; SINDRUP SH; BROSEN K; POULSEN JH; AAESJORGENSEN T; OVERO KF CITALOPRAM - INTERACTION STUDIES WITH LEVOMEPROMAZINE, IMIPRAMINE, AND LITHIUM	65	12
8846	4	8846 1993 THERAPEUTIC DRUG MONITORING 15(3):243-246 SPINA E; POLLICINO AM; AVENOSO A; CAMPO GM; PERUCCA E; CAPUTI AP EFFECT OF FLUVOXAMINE ON THE PHARMACOKINETICS OF IMIPRAMINE AND DESIPRAMINE IN HEALTHY-SUBJECTS	82	18
8847	2	8847 1993 THERAPEUTIC DRUG MONITORING 15(3):258-260 BROSEN K; KRAGHSORENSEN P CONCOMITANT INTAKE OF NORTRIPTYLINE AND CARBAMAZEPINE	29	7
8848	13	8848 1993 THERAPIE 48(6):521-526 BEAUNE P HUMAN CYTOCHROMES P450 - APPLICATIONS IN PHARMACOLOGY	13	3
8849	27	8849 1993 THERAPIE 48(6):527-536 BATT AM; STRAZIELLE N; SIEGST G INDUCTION AND REPRESSION OF CYTOCHROMES P450 - IN-VIVO AND IN- VITRO METHODS	3	2
8850	13	8850 1993 THERAPIE 48(6):537-548 PESSAYRE D CYTOCHROMES P450 AND FORMATION OF REACTIVE METABOLITES - ROLE IN DRUG-INDUCED HEPATOTOXICITY	5	2
8851	3	8851 1993 THYROID 3(1):49-53 GAITAN E; COOKSEY RC; LEGAN J; CRUSE JM; LINDSAY RH; HILL J ANTITHYROID AND GOITROGENIC EFFECTS OF COAL-WATER EXTRACTS FROM IODINE-SUFFICIENT GOITER AREAS	2	1
8852	13	8852 1993 THYROID 3(2):143-159 MEDEIROSNETO GA; BILLERBECK AEC; WAJCHENBERG BL; TARGOVNIK HM DEFECTIVE ORGANIFICATION OF IODIDE CAUSING HEREDITARY GOITROUS HYPOTHYROIDISM	11	1
8853	5	8853 1993 TOXICOLOGY 79(3):169-180 VALENTOVIC MA; BALL JG; ANESTIS D; MADAN E MODIFICATION OF P450 ACTIVITY AND ITS EFFECT ON 1,2- DICHLOROBENZENE TOXICITY IN FISCHER-344 RATS	9	0
8854	17	8854 1993 TOXICOLOGY 80(1):27-35 PAPPAS JB; FRANKLIN MR HEPATIC CLOTRIMAZOLE CONCENTRATIONS AND HEPATIC DRUG- METABOLIZING ENZYME-ACTIVITIES IN ADULT MALE SPRAGUE-DAWLEY RATS	4	1
8855	16	8855 1993 TOXICOLOGY 81(2):145-154 UENG TH; UENG YF; TSAI JN; CHAO IC; CHEN TL; PARK SS; IWASAKI M; GUENGERICH FP INDUCTION AND INHIBITION OF CYTOCHROME P-450-DEPENDENT MONOOXYGENASES IN HAMSTER TISSUES BY ETHANOL	20	4
8856	21	8856 1993 TOXICOLOGY 82(1-3):21-37 GUENGERICH FP; GILLAM EMJ; OHMORI S; SANDHU P; BRIAN WR; SARI MA; IWASAKI M EXPRESSION OF HUMAN CYTOCHROME-P450 ENZYMES IN YEAST AND BACTERIA AND RELEVANCE TO STUDIES ON CATALYTIC SPECIFICITY	15	11
8857	14	8857 1993 TOXICOLOGY 82(1-3):39-52 RENAUD JP; PEYRONNEAU MA; URBAN P; TRUAN G; CULLIN C; POMPON D; BEAUNE P; MANSUY D RECOMBINANT YEAST IN DRUG-METABOLISM	28	18
8858	15	8858 1993 TOXICOLOGY 82(1-3):77-88 GONZALEZ FJ MOLECULAR-BIOLOGY OF HUMAN XENOBIOTIC-METABOLIZING CYTOCHROMES- P450 - ROLE OF VACCINIA VIRUS CDNA EXPRESSION IN EVALUATING CATALYTIC FUNCTION	8	7
8859	7	8859 1993 TOXICOLOGY 83(1-3):41-48 LAMMINEN S; PYYKKO K; RORARIUS M; TUIMALA R CYTOCHROME P450IA1 ACTIVITY IN HUMAN MYOMETRIUM AND UTERINE LEIOMYOMA - INFLUENCE OF SMOKING	1	0
8860	12	8860 1993 TOXICOLOGY AND APPLIED PHARMACOLOGY 118(2):169-176 LOUIS CA; SINCLAIR JF; WOOD SG; LAMBRECHT LK; SINCLAIR PR; SMITH EL SYNERGISTIC INDUCTION OF CYTOCHROME-P450 BY ETHANOL AND ISOPENTANOL IN CULTURES OF CHICK-EMBRYO AND RAT HEPATOCYTES	12	6
8861	11	8861 1993 TOXICOLOGY AND APPLIED PHARMACOLOGY 118(2):255-262 POSTLIND H; VU TP; TUKEY RH; QUATTROCHI LC RESPONSE OF HUMAN CYP1-LUCIFERASE PLASMIDS TO 2,3,7,8- TETRACHLORODIBENZO-P-DIOXIN AND POLYCYCLIC AROMATIC- HYDROCARBONS	64	7
8862	22	8862 1993 TOXICOLOGY AND APPLIED PHARMACOLOGY 119(1):66-73 UENG TH; UENG YF; CHEN TL; PARK SS; IWASAKI M; GUENGERICH FP INDUCTION OF CYTOCHROME-P450-DEPENDENT MONOOXYGENASES IN HAMSTER TISSUES BY FASTING	28	7
8863	4	8863 1993 TOXICOLOGY AND APPLIED PHARMACOLOGY 119(2):236-247 SILKWORTH JB; CUTLER DS; OKEEFE PW; LIPINSKAS T POTENTIATION AND ANTAGONISM OF 2,3,7,8-TETRACHLORODIBENZO-P- DIOXIN EFFECTS IN A COMPLEX ENVIRONMENTAL MIXTURE	20	0
8864	8	8864 1993 TOXICOLOGY AND APPLIED PHARMACOLOGY 120(2):257-265 KIM SG; NOVAK RF THE INDUCTION OF CYTOCHROME-P4502E1 BY NITROGEN-CONTAINING AND SULFUR-CONTAINING HETEROCYCLES - EXPRESSION AND MOLECULAR REGULATION	48	4
8865	10	8865 1993 TOXICOLOGY AND APPLIED PHARMACOLOGY 120(2):298-307 KOCAREK TA; SCHUETZ EG; GUZELIAN PS REGULATION OF PHENOBARBITAL-INDUCIBLE CYTOCHROME-P450 2B1/2 MESSENGER-RNA BY LOVASTATIN AND OXYSTEROLS IN PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES	25	3
8866	10	8866 1993 TOXICOLOGY AND APPLIED PHARMACOLOGY 123(1):34-42 TAI HL; MCREYNOLDS JH; GOLDSTEIN JA; EUGSTER HP; SENGSTAG C; ALWORTH WL; OLSON JR CYTOCHROME-P4501A1 MEDIATES THE METABOLISM OF 2,3,7,8- TETRACHLORODIBENZOFURAN IN THE RAT AND HUMAN	20	3
8867	7	8867 1993 TOXICOLOGY IN VITRO 7(5):605-614 LAKE BG; LEWIS DFV; GRAY TJB; BEAMAND JA STRUCTURE-ACTIVITY-RELATIONSHIPS FOR INDUCTION OF PEROXISOMAL ENZYME-ACTIVITIES IN PRIMARY RAT HEPATOCYTE CULTURES	14	1
8868	5	8868 1993 TOXICOLOGY IN VITRO 7(6):685-& JONES C; GREINER B; WACHTER F; TERLOUW GDC; BECHTER R AN IMMUNOHISTOCHEMICAL INVESTIGATION INTO THE PRESENCE AND LOCALIZATION OF CYTOCHROME-P-450 ISOZYMES IN ORGANOGENESIS- STAGE RAT CONCEPTAL TISSUE	0	0
8869	4	8869 1993 TOXICOLOGY IN VITRO 7(6):769-775 VANAERTS LAGJM; HAHNE SJM; OOSTENDORP AGM; PERTIJS JCLM; FIJNEMAN PHS; BOS RP; PEEREBOOM JHJC; NOORDHOEK J SEX DIFFERENCE IN AROCLOR-1254 INDUCTION OF RAT HEPATOCYTES - CONSEQUENCES FOR IN-VITRO EMBRYOTOXICITY AND MUTAGENICITY OF CYCLOPHOSPHAMIDE	1	0
8870	16	8870 1993 TRENDS IN ENDOCRINOLOGY AND METABOLISM 4(2):46-50 PARKER KL; SCHIMMER BP TRANSCRIPTIONAL REGULATION OF THE ADRENAL STEROIDOGENIC ENZYMES	50	6
8871	7	8871 1993 TRENDS IN PHARMACOLOGICAL SCIENCES 14(8):292-294 BIRKETT DJ; MACKENZIE PI; VERONESE ME; MINERS JO IN-VITRO APPROACHES CAN PREDICT HUMAN DRUG-METABOLISM	63	15
8872	10	8872 1993 VETERINARNI MEDICINA 38(12):739-750 MACHALA M CYTOCHROMES P450 - TOXICOLOGICAL SIGNIFICANCE OF LEVEL DETERMINATION	0	0
8873	7	8873 1993 WATER RESEARCH 27(3):449-455 VINDIMIAN E; NAMOUR P; MUNOZ JF; GRIL JJ; MIGEON B; GARRIC J ETHOXYRESORUFIN-O-DEETHYLASE INDUCTION IN FISH FROM A WATERSHED EXPOSED TO A NONPOINT SOURCE POLLUTION OF AGRICULTURAL ORIGIN	10	2
8874	13	8874 1993 XENOBIOTICA 23(1):71-78 ENGELKE M; BERGMANN U; DIEHL HA FLUIDITY OF THE MICROSOMAL MEMBRANE AND CYTOCHROME-P450 REDUCTION KINETICS OF PIG-LIVER MICROSOMES AS A CONSEQUENCE OF ORGANIC-SOLVENT IMPACT	14	2
8875	3	8875 1993 XENOBIOTICA 23(1):79-96 LEWIS DFV; LAKE BG INTERACTION OF SOME PEROXISOME PROLIFERATORS WITH THE MOUSE- LIVER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR) - A MOLECULAR MODELING AND QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP (QSAR) STUDY	28	5
8876	8	8876 1993 XENOBIOTICA 23(2):169-179 JAPENGA AC; DAVIES S; PRICE RJ; LAKE BG EFFECT OF TREATMENT WITH PYRAZINE AND SOME DERIVATIVES ON CYTOCHROME-P450 AND SOME ENZYME-ACTIVITIES IN RAT-LIVER	17	8
8877	4	8877 1993 XENOBIOTICA 23(3):217-225 KIM ND; YOO JK; WON SM; PARK SS; GELBOIN HV PHENYTOIN INDUCTION OF CYTOCHROME P4502B IN MICE - EFFECTS ON HEXOBARBITAL HYDROXYLASE-ACTIVITY	7	1
8878	22	8878 1993 XENOBIOTICA 23(3):227-239 IBA MM; GANDER JE; MANNERING GJ LIPID PEROXIDATION-CYTOCHROME P450 INTERACTIONS - USE OF LINOLEIC-ACID HYDROPEROXIDE IN THE CHARACTERIZATION OF THE SPIN-STATE OF MEMBRANE-BOUND P450	3	1
8879	11	8879 1993 XENOBIOTICA 23(3):267-277 FRANKLIN MR; SLAWSON MH; MOODY DE SELECTIVE INDUCTION OF RAT-LIVER PHASE-II ENZYMES BY N- HETEROCYCLE ANALOGS OF PHENANTHRENE - A RESPONSE EXHIBITING HIGH CORRELATION BETWEEN UDP-GLUCURONOSYLTRANSFERASE AND MICROSOMAL EPOXIDE HYDROLASE ACTIVITIES	11	6
8880	5	8880 1993 XENOBIOTICA 23(4):419-426 OHMORI S; TANIGUCHI T; RIKIHISA T; KANAKUBO Y; KITADA M SPECIES-DIFFERENCES OF TESTOSTERONE 16-HYDROXYLASES IN LIVER- MICROSOMES OF GUINEA-PIG, RAT AND DOG	18	7
8881	6	8881 1993 XENOBIOTICA 23(6):633-648 KOYMANS L; DENKELDER GMD; TEKOPPELE JM; VERMEULEN NPE GENERALIZED CYTOCHROME P450-MEDIATED OXIDATION AND OXYGENATION REACTIONS IN AROMATIC SUBSTRATES WITH ACTIVATED N-H, O-H, C-H, OR S-H SUBSTITUENTS	12	2
8882	3	8882 1993 XENOBIOTICA 23(11):1289-1298 SU P; COUTTS RT; BAKER GB; DANESHTALAB M ANALYSIS OF IMIPRAMINE AND 3 METABOLITES PRODUCED BY ISOZYME CYP2D6 EXPRESSED IN A HUMAN CELL-LINE	20	10
8883	12	8883 1993 XENOBIOTICA 23(12):1353-1366 BACKES WL; SEQUEIRA DJ; CAWLEY GF; EYER CS RELATIONSHIP BETWEEN HYDROCARBON STRUCTURE AND INDUCTION OF P450 - EFFECTS ON PROTEIN-LEVELS AND ENZYME-ACTIVITIES	19	6
8884	3	8884 1993 ZEITSCHRIFT FUR KARDIOLOGIE 82(10):601-609 SCHIMKE I; HABERLAND A OXYGEN RADICALS AND DISEASES OF THE HEART AND CIRCULATORY- SYSTEM - PATHOGENETIC MECHANISMS, THERAPEUTIC POSSIBILITIES	7	0
8885	33	8885 1994 ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY, VOL 68 68():37-66 WATERMAN MR HETEROLOGOUS EXPRESSION OF MAMMALIAN P450 ENZYMES	8	3
8886	13	8886 1994 AMERICAN JOURNAL OF MEDICINE 97():S13-S23 DEVANE CL PHARMACOKINETICS OF THE NEWER ANTIDEPRESSANTS - CLINICAL RELEVANCE	54	6
8887	2	8887 1994 AMERICAN JOURNAL OF PHYSIOLOGY 266(1):L101-L106 MASSARO GD; SINGH G; MASON R; PLOPPER CG; MALKINSON AM; GAIL DB BIOLOGY OF THE CLARA CELL	24	0
8888	7	8888 1994 AMERICAN JOURNAL OF PHYSIOLOGY 266(1):C243-C253 HUSSAIN H; SHORNICK LP; SHANNON VR; WILSON JD; FUNK CD; PENTLAND AP; HOLTZMAN MJ EPIDERMIS CONTAINS PLATELET-TYPE 12-LIPOXYGENASE THAT IS OVEREXPRESSED IN GERMINAL LAYER KERATINOCYTES IN PSORIASIS	58	0
8889	11	8889 1994 AMERICAN JOURNAL OF PHYSIOLOGY 266(5):H2098-H2107 HARDER DR; GEBREMEDHIN D; NARAYANAN J; JEFCOAT C; FALCK JR; CAMPBELL WB; ROMAN R FORMATION AND ACTION OF A P-450 4A METABOLITE OF ARACHIDONIC- ACID IN CAT CEREBRAL MICROVESSELS	87	13
8890	19	8890 1994 AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 11(4):386-396 PAIRON JC; TRABELSI N; BUARD A; FLEURYFEITH J; BACHELET CM; PORON F; BEAUNE P; BROCHARD P; LAURENT P CELL LOCALIZATION AND REGULATION OF EXPRESSION OF CYTOCHROME- P450 1A1 AND 2B1 IN RAT LUNG AFTER INDUCTION WITH 3- METHYLCHOLANTHRENE USING MESSENGER-RNA HYBRIDIZATION AND IMMUNOHISTOCHEMISTRY	11	3
8891	8	8891 1994 AMERICAN JOURNAL OF VETERINARY RESEARCH 55(11):1579-1586 KAWALEK JC; ELSAID KR COMPARISON OF MATURATION OF DRUG-METABOLIZING-ENZYMES IN CALVES WITH FUNCTIONING OR NONFUNCTIONING RUMEN	3	1
8892	2	8892 1994 ANAESTHESIA 49(3):188-191 PARK GR; PICHARD L; TINEL M; LARROQUE C; ELSTON A; DOMERQUE J; DEXIONNE B; MAUREL P WHAT CHANGES DRUG-METABOLISM IN CRITICALLY ILL PATIENTS - 2 PRELIMINARY STUDIES IN ISOLATED HUMAN HEPATOCYTES	17	3
8893	4	8893 1994 ANAESTHESIA 49(6):497-500 NOBLE DW; BANNISTER J; LAMONT M; ANDERSSON T; SCOTT DB THE EFFECT OF ORAL OMEPRAZOLE ON THE DISPOSITION OF LIGNOCAINE	8	1
8894	4	8894 1994 ANALYTICAL BIOCHEMISTRY 216(1):176-187 DIETZE EC; KUWANO E; HAMMOCK BD SPECTROPHOTOMETRIC SUBSTRATES FOR CYTOSOLIC EPOXIDE HYDROLASE	15	3
8895	12	8895 1994 ANALYTICAL BIOCHEMISTRY 218(1):80-86 BONFILS C; DAUJAT M; CHEVRON MP; DALETBELUCHE I ELECTROTRANSFER OF MICROSOMAL CYTOCHROME-P450 AFTER ISOELECTRIC-FOCUSING (IEF BLOTS) - RESOLUTION OF HUMAN 2A- ISOENZYMES AND 3A-ISOZYMES	7	3
8896	17	8896 1994 ANALYTICAL BIOCHEMISTRY 219(2):309-320 RODRIGUES AD; KUKULKA MJ; SURBER BW; THOMAS SB; UCHIC JT; ROTERT GA; MICHEL G; THOMEKROMER B; MACHINIST JM MEASUREMENT OF LIVER MICROSOMAL CYTOCHROME-P450 (CYP2D6) ACTIVITY USING [O-METHYL-C-14] DEXTROMETHORPHAN	52	20
8897	14	8897 1994 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH 33(19):1911-1919 ULLRICH V; BRUGGER R PROSTACYCLIN AND THROMBOXANE SYNTHASE - NEW ASPECTS OF HEMETHIOLATE CATALYSIS	36	6
8898	4	8898 1994 ANNALS OF NEUROLOGY 36(6):811-813 HALLER RG OXYGEN UTILIZATION AND DELIVERY IN METABOLIC MYOPATHIES	5	2
8899	35	8899 1994 ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 29 29():307-316 MINERS JO; VERONESE ME; BIRKETT DJ IN-VITRO APPROACHES FOR THE PREDICTION OF HUMAN DRUG-METABOLISM	24	5
8900	7	8900 1994 ANNUAL REVIEW OF NUTRITION 14():131-145 MASTERS BSS NITRIC-OXIDE SYNTHASES - WHY SO COMPLEX	77	6

#	Cited nodes	Nodes / Authors	GCS	LCS
8901	5	8901 1994 ANNUAL REVIEW OF PLANT PHYSIOLOGY AND PLANT MOLECULAR BIOLOGY 45():257-285 HASHIMOTO T; YAMADA Y ALKALOID BIOGENESIS - MOLECULAR ASPECTS	50	1
8902	6	8902 1994 ANTICANCER RESEARCH 14(6B):2597-2603 FRATTA D; SIMI S; RAINALDI G; GERVASI PG ROLE OF CYTOCHROME-P-450 ISOENZYMES IN THE BIOACTIVATION OF HYDROXY ANTHRAQUINONES	4	1
8903	4	8903 1994 AQUATIC TOXICOLOGY 28(1-2):107-126 FENT K; BUCHELI TD INHIBITION OF HEPATIC-MICROSOMAL MONOOXYGENASE SYSTEM BY ORGANOTINS IN-VITRO IN FRESH-WATER FISH	42	4
8904	12	8904 1994 AQUATIC TOXICOLOGY 28(3-4):147-167 LINDSTROMSEPPA P; KORYTKO PJ; HAHN ME; STEGEMAN JJ UPTAKE OF WATERBORNE 3,3',4,4'-TETRACHLOROBIPHENYL AND ORGAN AND CELL-SPECIFIC INDUCTION OF CYTOCHROME P4501A IN ADULT AND LARVAL FATHEAD MINNOW PIMEPHALES-PROMELAS	25	7
8905	7	8905 1994 AQUATIC TOXICOLOGY 29(3-4):147-162 VANDERWEIDEN MEJ; BLEUMINK R; SEINEN W; VANDENBERG M CONCURRENCE OF P450-1A INDUCTION AND TOXIC EFFECTS IN THE MIRROR CARP (CYPRINUS-CARPIO), AFTER ADMINISTRATION OF A LOW- DOSE OF 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN	27	4
8906	15	8906 1994 AQUATIC TOXICOLOGY 29(3-4):183-196 CELANDER M; NAF C; BROMAN D; FORLIN L TEMPORAL ASPECTS OF INDUCTION OF HEPATIC CYTOCHROME-P450 1A AND CONJUGATING ENZYMES IN THE VIVIPAROUS BLENNY (ZOARCES- VIVIPARUS) TREATED WITH PETROLEUM-HYDROCARBONS	24	5
8907	2	8907 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 308(1):1-7 TOGASHI H; SHINZAWA H; YONG H; TAKAHASHI T; NODA H; OIKAWA K; KAMADA H ASCORBIC-ACID RADICAL, SUPEROXIDE, AND HYDROXYL RADICAL ARE DETECTED IN REPERFUSION INJURY OF RAT-LIVER USING ELECTRON- SPIN-RESONANCE SPECTROSCOPY	21	1
8908	10	8908 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 308(2):380-386 WU FF; VERGERES G; WASKELL L KINETICS OF THE REDUCTION OF CYTOCHROME B(5) WITH MUTATIONS IN ITS MEMBRANE-BINDING DOMAIN	7	3
8909	17	8909 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 309(1):52-57 LOU ZS; HE YA; HALPERT JR ROLE OF RESIDUE-363 AND RESIDUE-206 IN CONVERSION OF CYTOCHROME-P450 2B1 FROM A STEROID 16-HYDROXYLASE TO A 15- ALPHA-HYDROXYLASE	0	0
8910	24	8910 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 309(1):168-177 SANDHU P; GUO ZY; BABA T; MARTIN MV; TUKEY RH; GUENGERICH FP EXPRESSION OF MODIFIED HUMAN CYTOCHROME-P450 1A2 IN ESCHERICHIA-COLI - STABILIZATION, PURIFICATION, SPECTRAL CHARACTERIZATION, AND CATALYTIC ACTIVITIES OF THE ENZYME	111	74
8911	15	8911 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 310(1):126-133 BLACK SD; LINGER MH; FRECK LC; KAZEMI S; GALBRAITH JA AFFINITY ISOLATION AND CHARACTERIZATION OF CYTOCHROME-P450-102 (BM-3) FROM BARBITURATE-INDUCED BACILLUS-MEGATERIUM	23	20
8912	11	8912 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 310(1):187-195 BERNDTSON AK; CHEN TT 2 UNIQUE CYP1 GENES ARE EXPRESSED IN RESPONSE TO 3- METHYLCHOLANTHRENE TREATMENT IN RAINBOW-TROUT	93	48
8913	13	8913 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 310(2):318-324 BHATTACHARYYA AK; HURLEY JK; TOLLIN G; WASKELL L INVESTIGATION OF THE RATE-LIMITING STEP FOR ELECTRON-TRANSFER FROM NADPH -CYTOCHROME-P450 REDUCTASE TO CYTOCHROME-B(5) - A LASER FLASH-PHOTOLYSIS STUDY	3	2
8914	6	8914 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 310(2):332-340 MA RL; COHEN MB; BERENBAUM MR; SCHULER MA BLACK SWALLOWTAIL (PAPILIO POLYXENES) ALLELES ENCODE CYTOCHROME P450S THAT SELECTIVELY METABOLIZE LINEAR FURANOCOUMARINS	44	21
8915	18	8915 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 310(2):397-401 HIROYA K; MURAKAMI Y; SHIMIZU T; HATANO M; DEMONTELLANO PRO DIFFERENTIAL ROLES OF GLU318 AND THR319 IN CYTOCHROME-P450-1A2 CATALYSIS SUPPORTED BY NADPH-CYTOCHROME-P450 REDUCTASE AND TERT-BUTYL HYDROPEROXIDE	16	7
8916	11	8916 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 310(2):452-459 OLEARY KA; BECK TW; KASPER CB NADPH CYTOCHROME-P-450 OXIDOREDUCTASE GENE - IDENTIFICATION AND CHARACTERIZATION OF THE PROMOTER REGION	16	8
8917	4	8917 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 311(2):369-377 RETTIE AE; LAWTON MP; SADEQUE AJM; MEIER GP; PHILPOT RM PROCHIRAL SULFOXIDATION AS A PROBE FOR MULTIPLE FORMS OF THE MICROSOMAL FLAVIN-CONTAINING MONOOXYGENASE - STUDIES WITH RABBIT FMO1, FMO2, FMO3, AND FMO5 EXPRESSED IN ESCHERICHIA-COLI	19	3
8918	11	8918 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 311(2):395-401 OHMORI S; CHIBA K; NAKASA H; HORIE T; KITADA M CHARACTERIZATION OF MONKEY CYTOCHROME-P450, P450-CMLD, RESPONSIBLE FOR S-MEPHENYTOIN 4'-HYDROXYLATION IN HEPATIC MICROSOMES OF CYNOMOLGUS MONKEYS	17	7
8919	27	8919 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 311(2):402-417 SHET MS; FISHER CW; ARLOTTO MP; SHACKLETON CHL; HOLMANS PL; MARTINWIXTROM CA; SAEKI Y; ESTABROOK RW PURIFICATION AND ENZYMATIC-PROPERTIES OF A RECOMBINANT FUSION PROTEIN EXPRESSED IN ESCHERICHIA-COLI CONTAINING THE DOMAINS OF BOVINE P450 17A AND RAT NADPH-P450 REDUCTASE	45	45
8920	28	8920 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 311(2):437-442 CHANG TKH; GONZALEZ FJ; WAXMAN DJ EVALUATION OF TRIACETYLOLEANDOMYCIN, ALPHA-NAPHTHOFLAVONE AND DIETHYLDITHIOCARBAMATE AS SELECTIVE CHEMICAL PROBES FOR INHIBITION OF HUMAN CYTOCHROMES P450	195	46
8921	11	8921 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 312(1):45-51 BUHLER DR; YANG YH; DREHER TW; MIRANDA CL; WANG JL CLONING AND SEQUENCING OF THE MAJOR RAINBOW-TROUT CONSTITUTIVE CYTOCHROME-P450 (CYP2K1) - IDENTIFICATION OF A NEW CYTOCHROME- P450 GENE SUBFAMILY AND ITS EXPRESSION IN MATURE RAINBOW-TROUT LIVER AND TRUNK KIDNEY	35	18
8922	26	8922 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 312(1):59-66 GILLAM EMJ; GUO ZY; GUENGERICH FP EXPRESSION OF MODIFIED HUMAN CYTOCHROME-P450 2E1 IN ESCHERICHIA-COLI, PURIFICATION, AND SPECTRAL AND CATALYTIC PROPERTIES	75	45
8923	29	8923 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 312(2):436-446 GUO ZY; GILLAM EMJ; OHMORI S; TUKEY RH; GUENGERICH FP EXPRESSION OF MODIFIED HUMAN CYTOCHROME-P450-1A1 IN ESCHERICHIA-COLI - EFFECTS OF 5' SUBSTITUTION, STABILIZATION, PURIFICATION, SPECTRAL CHARACTERIZATION, AND CATALYTIC PROPERTIES	64	0
8924	24	8924 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 312(2):554-565 HOLMANS PL; SHET MS; MARTINWIXTROM CA; FISHER CW; ESTABROOK RW THE HIGH-LEVEL EXPRESSION IN ESCHERICHIA-COLI OF THE MEMBRANE- BOUND FORM OF HUMAN AND RAT CYTOCHROME B(5) AND STUDIES ON THEIR MECHANISM OF FUNCTION	42	42
8925	18	8925 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 314(1):234-241 SCHENKMAN JB; VOZNESENSKY AI; JANSSON I INFLUENCE OF IONIC-STRENGTH ON THE P450 MONOOXYGENASE REACTION AND ROLE OF CYTOCHROME B(5) IN THE PROCESS	30	22
8926	2	8926 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 314(2):280-283 VOTYAKOVA TV; ARTZATBANOV VY; MUKAMOLOVA GV; KAPRELYANTS AS ON THE RELATIONSHIP BETWEEN BACTERIAL-CELL INTEGRITY AND RESPIRATORY-CHAIN ACTIVITY - A FLUORESCENCE ANISOTROPY STUDY	2	0
8927	10	8927 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 314(2):351-359 MIYATA M; NAGATA K; SHIMADA M; YAMAZOE Y; KATO R STRUCTURE OF A GENE AND CDNA OF A MAJOR CONSTITUTIVE FORM OF TESTOSTERONE 6-BETA-HYDROXYLASE (P450/6-BETA-A) ENCODING CYP3A2 - COMPARISON OF THE CDNA WITH P450PCN2	27	16
8928	17	8928 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 314(2):367-375 JOHN GH; HASLER JA; HE YA; HALPERT JR ESCHERICHIA-COLI EXPRESSION AND CHARACTERIZATION OF CYTOCHROMES P450 2B11, 2B1, AND 2B5	49	23
8929	2	8929 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 315(2):273-278 WANG LH; TAZAWA R; LANG AQ; WU KK ALTERNATE SPLICING OF HUMAN THROMBOXANE SYNTHASE MESSENGER-RNA	15	5
8930	14	8930 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 315(2):438-444 YANG MX; CEDERBAUM AI FRACTIONATION OF LIVER-MICROSOMES WITH POLYETHYLENE-GLYCOL AND PURIFICATION OF NADH-CYTOCHROME B(5) OXIDOREDUCTASE AND CYTOCHROME B(5)	14	7
8931	10	8931 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 315(2):454-459 DING XX; COON MJ STEROID-METABOLISM BY RABBIT OLFACTORY-SPECIFIC P450 2G1	25	15
8932	11	8932 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 315(2):489-494 BARNES HJ; JENKINS CM; WATERMAN MR BACULOVIRUS EXPRESSION OF BOVINE CYTOCHROME P450C17 IN SF9 CELLS AND COMPARISON WITH EXPRESSION IN YEAST, MAMMALIAN-CELLS, AND ESCHERICHIA-COLI	22	18
8933	19	8933 1994 ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY 27(3):205-216 ZHANG ML; SCOTT JG CYTOCHROME B(5) INVOLVEMENT IN CYTOCHROME-P450 MONOOXYGENASE ACTIVITIES IN-HOUSE FLY MICROSOMES	15	8
8934	15	8934 1994 ARCHIVES OF TOXICOLOGY 68(7):416-422 PELKONEN P; LANG M; PASANEN M TISSUE AND SEX-DEPENDENT DIFFERENCES IN CYP2A ACTIVITIES IN HAMSTERS	5	4
8935	2	8935 1994 ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY 22(4):1237-1242 SHREWSBURY RP; OLIVER SR; WHITE LG THE EFFECT OF MODERATE HEMODILUTION WITH FLUOSOL(R) ON CYTOCHROME P4502D6 ACTIVITY IN THE RAT	0	0
8936	1	8936 1994 BAILLIERES CLINICAL ENDOCRINOLOGY AND METABOLISM 8(4):803-824 NUNEZ EA; CHRISTEFF N STEROID-HORMONE, CYTOKINE, LIPID AND METABOLIC DISTURBANCES IN HIV-INFECTION	11	1
8937	5	8937 1994 BIOCATALYSIS 10(1-4):233-246 ASPERGER O; WIRKNER K; SCHMIDT M; FLECHSIG E DETECTION OF DIVERSE CYTOCHROME P450-DEPENDENT BIOOXYGENATION CATALYSTS IN MICROORGANISMS USING A MULTIPURPOSE INDUCER	3	2
8938	6	8938 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 198(2):795-803 PINOT F; ALAYRAC C; MIOSKOWSKI C; DURST F; SALAUN JP NEW CYTOCHROME P450-DEPENDENT REACTIONS FROM WHEAT - TERMINAL AND SUB-TERMINAL HYDROXYLATION OF OLEIC-ACID BY MICROSOMES FROM NAPHTHALIC ACID ANHYDRIDE AND PHENOBARBITAL INDUCED WHEAT SEEDLINGS	12	5
8939	3	8939 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 198(3):862-868 GAIDAMAKOVA EK; KARGINOV VA; KOVALENKO SP PROTEIN-BINDING DNA REGIONS INSIDE AND IN THE VICINITY OF THE CYTOCHROME P450BM-3 GENE FROM BACILLUS-MEGATERIUM	3	0
8940	6	8940 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 200(1):120-125 ZEILMAKER WM; VANTKLOOSTER GAE; GREMMELSGEHRMANN JF; VANMIERT ASJPAM; HORBACH GJMJ CDNA AND DEDUCED AMINO-ACID-SEQUENCE OF A DWARF GOAT LIVER CYTOCHROME-P450 FRAGMENT BELONGING TO THE CYP2C GENE SUBFAMILY	6	4
8941	4	8941 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 200(2):722-725 UVAROV VY; SHUMYANTSEVA VV; BYKHOVSKAYA EA; KOLYADA LN; ARCHAKOV AL SEMIARTIFICIAL HYDROXYLATING ENZYMES CREATED BY FLAVINS BINDING TO CYTOCHROME-P450 2B4 AND BY BLEOMYCIN BINDING TO NADPH- CYTOCHROME P450 REDUCTASE	12	11
8942	3	8942 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 201(1):373-378 LEFEVER MR; WACKETT LP OXIDATION OF LOW-MOLECULAR-WEIGHT CHLOROALKANES BY CYTOCHROME P450(CAM)	8	3
8943	13	8943 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 201(2):973-979 WRIGHT MC; PAINE AJ INDUCTION OF THE CYTOCHROME-P450-3A SUBFAMILY IN RAT-LIVER CORRELATES WITH THE BINDING OF INDUCERS TO A MICROSOMAL PROTEIN	21	12
8944	9	8944 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 201(3):1320-1326 AOYAMA Y; FUNAE Y; NOSHIRO M; HORIUCHI T; YOSHIDA Y OCCURRENCE OF A P450 SHOWING HIGH HOMOLOGY TO YEAST LANOSTEROL 14-DEMETHYLASE (P450(14DM)) IN THE RAT-LIVER	43	19
8945	7	8945 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 201(3):1464-1469 EGAWA T; SHIMADA H; ISHIMURA Y EVIDENCE FOR COMPOUND I FORMATION IN THE REACTION OF CYTOCHROME-P450CAM WITH M-CHLOROPERBENZOIC ACID	40	6
8946	3	8946 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 202(1):586-590 NAKAYAMA N; SHOUN H FATTY-ACID HYDROXYLASE OF THE FUNGUS FUSARIUM-OXYSPORUM IS POSSIBLY A FUSED PROTEIN OF CYTOCHROME-P-450 AND ITS REDUCTASE	9	5
8947	16	8947 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 202(3):1731-1737 VILLARD PH; SEREE E; LACARELLE B; THERENEFENOGLIO MC; BARRA Y; ATTOLINI L; BRUGUEROLE B; DURAND A; CATALIN J EFFECT OF CIGARETTE-SMOKE ON HEPATIC AND PULMONARY CYTOCHROMES P450 IN MOUSE - EVIDENCE FOR CYP2E1 INDUCTION IN LUNG	36	13
8948	16	8948 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 203(1):162-168 BLACK SD ON THE DOMAIN-STRUCTURE OF CYTOCHROME-P450-102 (BM-3) - ISOLATION AND PROPERTIES OF A 45-KDA FAD/NADP DOMAIN	6	4
8949	8	8949 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 203(1):373-378 DING XX; PENG HM; COON MJ STRUCTURE-FUNCTION ANALYSIS OF CYP2A10 AND CYP2A11, P450 CYTOCHROMES THAT DIFFER IN ONLY 8 AMINO-ACIDS BUT HAVE STRIKINGLY DIFFERENT ACTIVITIES TOWARD TESTOSTERONE AND COUMARIN	6	0
8950	5	8950 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 203(2):866-873 NOVIKOVA LA; SAVELEV AS; LUZIKOV VN A MODIFIED FORM OF THE CYTOCHROME P450SCC PRECURSOR - A NEW APPROACH IN STUDIES ON PROTEIN IMPORT INTO MITOCHONDRIA	1	0
8951	11	8951 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 203(2):1168-1174 AMET Y; BERTHOU F; GOASDUFF T; SALAUN JP; LEBRETON L; MENEZ JF EVIDENCE THAT CYTOCHROME-P450 2E1 IS INVOLVED IN THE (OMEGA-1)- HYDROXYLATION OF LAURIC ACID IN RAT-LIVER MICROSOMES	49	23
8952	4	8952 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 203(3):1745-1749 GONVINDARAJ S; LI HY; POULOS TL FLAVIN SUPPORTED FATTY-ACID OXIDATION BY THE HEME DOMAIN OF BACILLUS-MEGATERIUM CYTOCHROME-P450(BM-3)	3	3
8953	6	8953 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 205(1):631-637 SALONPAA P; PELKONEN O; KOJO A; PASANEN M; NEGISHI M; RAUNIO H CYTOCHROME P4502A5 EXPRESSION AND INDUCIBILITY BY PHENOBARBITAL IS MODULATED BY CAMP IN MOUSE PRIMARY HEPATOCYTES	25	8
8954	12	8954 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 205(2):1086-1092 BOTTO F; SEREE E; ELKHYARI S; CAU P; HENRIC A; DEMEO M; BERGERON P; BARRA Y HYPOMETHYLATION AND HYPOEXPRESSION OF HUMAN CYP2E1 GENE IN LUNG-TUMORS	8	4
8955	6	8955 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 205(2):1452-1459 SCOTT JA; COLLINS FH; FEYEREISEN R DIVERSTY OF CYTOCHROME-P450 GENES IN THE MOSQUITO, ANOPHELES- ALBIMANUS	41	24
8956	18	8956 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 205(3):1741-1747 JOUNAIDI Y; GUZELIAN PS; MAUREL P; VILAREM MJ SEQUENCE OF THE 5'-FLANKING REGION OF CYP3A5 - COMPARATIVE- ANALYSIS WITH CYP3A4 AND CYP3A7	34	22
8957	10	8957 1994 BIOCHEMICAL JOURNAL 299():711-717 CHEN JH; HARA T; FISHER MJ; REES HH IMMUNOLOGICAL ANALYSIS OF DEVELOPMENTAL-CHANGES IN ECDYSONE 20- MONO-OXYGENASE EXPRESSION IN THE COTTON LEAFWORM, SPODOPTERA- LITTORALIS	16	1
8958	14	8958 1994 BIOCHEMICAL JOURNAL 301():753-758 RAM PA; WAXMAN DJ DEHYDROEPIANDROSTERONE 3-BETA-SULFATE IS AN ENDOGENOUS ACTIVATOR OF THE PEROXISOME-PROLIFERATION PATHWAY - INDUCTION OF CYTOCHROME-P-450 4A AND ACYL-COA OXIDASE MESSENGER-RNAS IN PRIMARY RAT HEPATOCYTE CULTURE AND INHIBITORY EFFECTS OF CA2+- CHANNEL BLOCKERS	25	15
8959	12	8959 1994 BIOCHEMICAL JOURNAL 303():423-428 MUNRO AW; MALARKEY K; MCKNIGHT J; THOMSON AJ; KELLY SM; PRICE NC; LINDSAY JG; COGGINS JR; MILES JS THE ROLE OF TRYPTOPHAN-97 OF CYTOCHROME-P450-BM3 FROM BACILLUS- MEGATERIUM IN CATALYTIC FUNCTION - EVIDENCE AGAINST THE COVALENT-SWITCHING HYPOTHESIS OF P-450 ELECTRON-TRANSFER	18	11
8960	9	8960 1994 BIOCHEMICAL JOURNAL 304():687-692 LOEBER G; MAURERFOGY I; SCHWENDENWEIN R PURIFICATION, CDNA CLONING AND HETEROLOGOUS EXPRESSION OF THE HUMAN MITOCHONDRIAL NADP(+)-DEPENDENT MALIC ENZYME	7	2
8961	14	8961 1994 BIOCHEMICAL PHARMACOLOGY 47(1):25-37 NEBERT DW DRUG-METABOLIZING-ENZYMES IN LIGAND-MODULATED TRANSCRIPTION	155	44
8962	15	8962 1994 BIOCHEMICAL PHARMACOLOGY 47(4):727-735 SHIRAGA T; MATSUDA H; NAGASE K; IWASAKI K; NODA K; YAMAZAKI H; SHIMADA T; FUNAE Y METABOLISM OF FK506, A POTENT IMMUNOSUPPRESSIVE AGENT, BY CYTOCHROME-P450 3A ENZYMES IN RAT, DOG AND HUMAN LIVER- MICROSOMES	38	5
8963	24	8963 1994 BIOCHEMICAL PHARMACOLOGY 47(5):763-773 WEAVER RJ; THOMPSON S; SMITH G; DICKINS M; ELCOMBE CR; MAYER RT; BURKE MD A COMPARATIVE-STUDY OF CONSTITUTIVE AND INDUCED ALKOXYRESORUFIN O-DEALKYLATION AND INDIVIDUAL CYTOCHROME-P450 FORMS IN CYNOMOLGUS MONKEY (MACACA-FASCICULARIS), HUMAN, MOUSE, RAT AND HAMSTER LIVER-MICROSOMES	49	16
8964	15	8964 1994 BIOCHEMICAL PHARMACOLOGY 47(5):893-903 HAASCH ML; GRAF WK; QUARDOKUS EM; MAYER RT; LECH JJ USE OF 7-ALKOXYPHENOXAZONES, 7-ALKOXYCOUMARINS AND 7- ALKOXYQUINOLINES AS FLUORESCENT SUBSTRATES FOR RAINBOW-TROUT HEPATIC MICROSOMES AFTER TREATMENT WITH VARIOUS INDUCERS	16	5
8965	7	8965 1994 BIOCHEMICAL PHARMACOLOGY 47(6):1061-1066 TANAKA K; ODA Y; ASADA A; FUJIMORI M; FUNAE Y METABOLISM OF LIDOCAINE BY RAT PULMONARY CYTOCHROME-P450	11	1
8966	9	8966 1994 BIOCHEMICAL PHARMACOLOGY 47(7):1221-1229 PAMPORI NA; SHAPIRO BH EFFECTS OF NEONATALLY ADMINISTERED MONOSODIUM GLUTAMATE ON THE SEXUALLY DIMORPHIC PROFILES OF CIRCULATING GROWTH-HORMONE REGULATING MURINE HEPATIC MONOOXYGENASES	13	5
8967	20	8967 1994 BIOCHEMICAL PHARMACOLOGY 47(9):1643-1653 GORSKI JC; HALL SD; VANDENBRANDEN M; WRIGHTON SA; JONES DR REGIOSELECTIVE BIOTRANSFORMATION OF MIDAZOLAM BY MEMBERS OF THE HUMAN CYTOCHROME-P450-3A (CYP3A) SUBFAMILY	148	35
8968	19	8968 1994 BIOCHEMICAL PHARMACOLOGY 47(10):1883-1895 BERTHOU F; DREANO Y; BELLOC C; KANGAS L; GAUTIER JC; BEAUNE P INVOLVEMENT OF CYTOCHROME-P450 3A ENZYME FAMILY IN THE MAJOR METABOLIC PATHWAYS OF TOREMIFENE IN HUMAN LIVER-MICROSOMES	44	13
8969	3	8969 1994 BIOCHEMICAL PHARMACOLOGY 47(12):2213-2219 CAI YO; SOHLENIUS AK; ANDERSSON K; SUNDBERG C; DEPIERRE JW EFFECTS OF ACETYLSALICYLIC-ACID ON PARAMETERS RELATED TO PEROXISOME PROLIFERATION IN MOUSE-LIVER	12	2
8970	23	8970 1994 BIOCHEMICAL PHARMACOLOGY 48(1):59-64 HAKKOLA J; PASANEN M; PURKUNEN R; SAARIKOSKI S; PELKONEN O; MAENPAA J; RANE A; RAUNIO H EXPRESSION OF XENOBIOTIC-METABOLIZING CYTOCHROME-P450 FORMS IN HUMAN ADULT AND FETAL LIVER	95	33
8971	14	8971 1994 BIOCHEMICAL PHARMACOLOGY 48(1):161-171 BORNHEIM LM; EVERHART ET; LI JM; CORREIA MA INDUCTION AND GENETIC-REGULATION OF MOUSE HEPATIC CYTOCHROME- P450 BY CANNABIDIOL	5	1
8972	8	8972 1994 BIOCHEMICAL PHARMACOLOGY 48(1):197-200 RODRIGUES AD COMPARISON OF LEVELS OF ALDEHYDE OXIDASE WITH CYTOCHROME-P450 ACTIVITIES IN HUMAN LIVER IN-VITRO	20	7
8973	10	8973 1994 BIOCHEMICAL PHARMACOLOGY 48(2):311-317 QU W; KAUFFMAN FC; THURMAN RG FOOD RESTRICTION AND STIMULATION OF MONOOXYGENATION OF P- NITROANISOLE IN PERFUSED-RAT-LIVER	1	1
8974	5	8974 1994 BIOCHEMICAL PHARMACOLOGY 48(4):637-642 NAKAJIMA T; WANG RS; ELOVAARA E; GONZALEZ FJ; GELBOIN HV; VAINIO H; AOYAMA T CYP2C11 AND CYP2B1 ARE MAJOR CYTOCHROME-P450 FORMS INVOLVED IN STYRENE OXIDATION IN LIVER AND LUNG MICROSOMES FROM UNTREATED RATS, RESPECTIVELY	40	1
8975	23	8975 1994 BIOCHEMICAL PHARMACOLOGY 48(5):923-936 BURKE MD; THOMPSON S; WEAVER RJ; WOLF CR; MAYER RT CYTOCHROME-P450 SPECIFICITIES OF ALKOXYRESORUFIN O-DEALKYLATION IN HUMAN AND RAT-LIVER	194	54
8976	15	8976 1994 BIOCHEMICAL PHARMACOLOGY 48(6):1095-1103 BOTTO F; SEREE E; ELKHYARI S; DESOUSA G; MASSACRIER A; PLACIDI M; CAU P; PELLET W; RAHMANI R; BARRA Y TISSUE-SPECIFIC EXPRESSION AND METHYLATION OF THE HUMAN CYP2E1 GENE	21	12
8977	16	8977 1994 BIOCHEMICAL PHARMACOLOGY 48(7):1363-1369 MAENPAA J; JUVONEN R; RAUNIO H; RAUTIO A; PELKONEN O METABOLIC INTERACTIONS OF METHOXSALEN AND COUMARIN IN HUMANS AND MICE	30	7
8978	12	8978 1994 BIOCHEMICAL PHARMACOLOGY 48(7):1524-1527 YAMAZAKI H; MIMURA M; SUGAHARA C; SHIMADA T CATALYTIC ROLES OF RAT AND HUMAN CYTOCHROME-P450-2A ENZYMES IN TESTOSTERONE 7-ALPHA-HYDROXYLATION AND COUMARIN 7-HYDROXYLATION	26	18
8979	11	8979 1994 BIOCHEMICAL PHARMACOLOGY 48(9):1779-1783 MASIMIREMBWA CM; HASLER JA CHARACTERIZATION OF PRAZIQUANTEL METABOLISM BY RAT-LIVER MICROSOMES USING CYTOCHROME-P450 INHIBITORS	9	0
8980	16	8980 1994 BIOCHEMICAL PHARMACOLOGY 48(9):1807-1814 CHAPMAN DE; YANG HYL; WATTERS JJ; JUCHAU MR INDUCTION IN-VITRO AND COMPLETE CODING REGION SEQUENCE OF CYTOCHROME P4501A1 CDNA FROM CULTURED WHOLE RAT CONCEPTUSES DURING EARLY ORGANOGENESIS	6	2
8981	10	8981 1994 BIOCHEMICAL PHARMACOLOGY 48(10):1953-1965 RONIS MJJ; INGELMANSUNDBERG M; BADGER TM INDUCTION, SUPPRESSION AND INHIBITION OF MULTIPLE HEPATIC CYTOCHROME-P450 ISOZYMES IN THE MALE-RAT AND BOBWHITE QUAIL (COLINUS-VIRGINIANUS) BY ERGOSTEROL BIOSYNTHESIS INHIBITING FUNGICIDES (EBIFS)	29	2
8982	28	8982 1994 BIOCHEMICAL PHARMACOLOGY 48(12):2147-2156 RODRIGUES AD USE OF IN-VITRO HUMAN METABOLISM STUDIES IN DRUG DEVELOPMENT - AN INDUSTRIAL PERSPECTIVE	107	24
8983	3	8983 1994 BIOCHEMICAL SOCIETY TRANSACTIONS 22(2):S122-S122 NANJI M; CLAIR P; SHEPHARD EA; PHILLIPS IR EXPRESSION IN A BACULOVIRUS SYSTEM OF A CDNA-ENCODING HUMAN CYP2A6	1	0
8984	16	8984 1994 BIOCHEMISTRY 33(3):807-817 MILLER JP; WHITE RE PHOTOAFFINITY-LABELING OF CYTOCHROME-P450-2B4 - CAPTURE OF ACTIVE-SITE HEME LIGANDS BY A PHOTOCARBENE	12	5
8985	13	8985 1994 BIOCHEMISTRY 33(7):1743-1752 GOLDSTEIN JA; FALETTO MB; ROMKESSPARKS M; SULLIVAN T; KITAREEWAN S; RAUCY JL; LASKER JM; GHANAYEM BI EVIDENCE THAT CYP2C19 IS THE MAJOR (S)-MEPHENYTOIN 4'- HYDROXYLASE IN HUMANS	270	70
8986	16	8986 1994 BIOCHEMISTRY 33(8):2171-2177 ANDERSEN JF; UTERMOHLEN JG; FEYEREISEN R EXPRESSION OF HOUSE-FLY CYP6A1 AND NADPH-CYTOCHROME P450 REDUCTASE IN ESCHERICHIA-COLI AND RECONSTITUTION OF AN INSECTICIDE-METABOLIZING P450 SYSTEM	46	30
8987	13	8987 1994 BIOCHEMISTRY 33(12):3766-3771 ROBERTS ES; HOPKINS NE; ZALUZEC EJ; GAGE DA; ALWORTH WL; HOLLENBERG PF IDENTIFICATION OF ACTIVE-SITE PEPTIDES FROM H-3 LABELED 2- ETHYNYLNAPHTHALENE-INACTIVATED P450 2B1 AND 2B4 USING AMINO- ACID SEQUENCING AND MASS-SPECTROMETRY	38	11
8988	19	8988 1994 BIOCHEMISTRY 33(14):4419-4424 HE YA; LUO ZS; KLEKOTKA PA; BURNETT VL; HALPERT JR STRUCTURAL DETERMINANTS OF CYTOCHROME-P450-2B1 SPECIFICITY - EVIDENCE FOR 5 SUBSTRATE RECOGNITION SITES	58	34
8989	20	8989 1994 BIOCHEMISTRY 33(16):4933-4939 SAKAKI T; KOMINAMI S; TAKEMORI S; OHKAWA H; AKIYOSHISHIBATA M; YABUSAKI Y KINETIC-STUDIES ON A GENETICALLY-ENGINEERED FUSED ENZYME BETWEEN RAT CYTOCHROME P4501A1 AND YEAST NADPH-P450 REDUCTASE	51	30
8990	8	8990 1994 BIOCHEMISTRY 33(21):6442-6449 VAZ ADN; COON MJ ON THE MECHANISM OF ACTION OF CYTOCHROME-P450 - EVALUATION OF HYDROGEN ABSTRACTION IN OXYGEN-DEPENDENT ALCOHOL OXIDATION	45	13
8991	9	8991 1994 BIOCHEMISTRY 33(21):6450-6455 SHOU M; GROGAN J; MANCEWICZ JA; KRAUSZ KW; GONZALEZ FJ; GELBOIN HV; KORZEKWA KR ACTIVATION OF CYP3A4 - EVIDENCE FOR THE SIMULTANEOUS BINDING OF 2 SUBSTRATES IN A CYTOCHROME-P450 ACTIVE-SITE	170	62
8992	10	8992 1994 BIOCHEMISTRY 33(22):6945-6951 BLACK SD; MARTIN ST; SMITH CA MEMBRANE TOPOLOGY OF LIVER MICROSOMAL CYTOCHROME-P450 2B4 DETERMINED VIA MONOCLONAL-ANTIBODIES DIRECTED TO THE HALT- TRANSFER SIGNAL	19	5
8993	14	8993 1994 BIOCHEMISTRY 33(26):8029-8034 STRAUB P; LLOYD M; JOHNSON EF; KEMPER B DIFFERENTIAL-EFFECTS OF MUTATIONS IN SUBSTRATE RECOGNITION SITE-1 OF CYTOCHROME-P450-2C2 ON LAURIC ACID AND PROGESTERONE HYDROXYLATION	21	13
8994	2	8994 1994 BIOCHEMISTRY 33(32):9692-9698 FITTON V; RIGOULET M; OUHABI R; GUERIN B MECHANISTIC STOICHIOMETRY OF YEAST MITOCHONDRIAL OXIDATIVE- PHOSPHORYLATION	35	0
8995	13	8995 1994 BIOCHEMISTRY 33(40):12056-12062 BLACK SD; MARTIN ST EVIDENCE FOR CONFORMATIONAL DYNAMICS AND MOLECULAR AGGREGATION IN CYTOCHROME-P450-102 (BM-3)	10	8
8996	14	8996 1994 BIOCHEMISTRY 33(43):12920-12929 HILDEBRANDT P; HEIBEL G; ANZENBACHER P; LANGE R; KRUGER V; STIER A CONFORMATIONAL-ANALYSIS OF MITOCHONDRIAL AND MICROSOMAL CYTOCHROME-P-450 BY RESONANCE RAMAN-SPECTROSCOPY	17	3
8997	9	8997 1994 BIOCHEMISTRY 33(47):13963-13966 FREEMAN JE; WOLF CR EVIDENCE AGAINST A ROLE FOR SERINE-129 IN DETERMINING MURINE CYTOCHROME-P450 CYP2E-1 PROTEIN-LEVELS	8	4
8998	8	8998 1994 BIOCHEMISTRY 33(49):14723-14732 RICHARDS MK; MARLETTA MA CHARACTERIZATION OF NEURONAL NITRIC-OXIDE SYNTHASE AND A C415H MUTANT, PURIFIED FROM A BACULOVIRUS OVEREXPRESSION SYSTEM	70	6
8999	7	8999 1994 BIOCHEMISTRY 33(49):14784-14791 OLKEN NM; OSAWA Y; MARLETTA MA CHARACTERIZATION OF THE INACTIVATION OF NITRIC-OXIDE SYNTHASE BY N-G-METHYL-L-ARGININE - EVIDENCE FOR HEME LOSS	49	1
9000	6	9000 1994 BIOCHEMISTRY-MOSCOW 59(4):383-387 GULYAEVA LF; GRISHANOVA AY; LYAKHOVICH VV INDUCTION OF CYTOCHROMES P-4501A AND P-4502B IN VARIOUS ORGANS OF RATS TREATED WITH HEXACHLOROBENZENE AND AROCHLOR-1254	0	0

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