#	Cited nodes	Nodes / Authors	GCS	LCS
101	1	546 1976 JOURNAL OF BIOLOGICAL CHEMISTRY 251(11):3442-3446 MIEYAL JJ; BLUMER JL ACCELERATION OF AUTOOXIDATION OF HUMAN OXYHEMOGLOBIN BY ANILINE AND ITS RELATION TO HEMOGLOBIN-CATALYZED ANILINE HYDROXYLATION	101	12
102	6	253 1972 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 183(2):458-& FOUTS JR; DEVEREUX TR DEVELOPMENTAL ASPECTS OF HEPATIC AND EXTRAHEPATIC DRUG- METABOLIZING ENZYME-SYSTEMS - MICROSOMAL ENZYMES AND COMPONENTS IN RABBIT LIVVER AND LUNG DURING FIRST MONTH OF LIFE	100	10
103	7	816 1980 KIDNEY INTERNATIONAL 18(5):636-647 ANDERS MW METABOLISM OF DRUGS BY THE KIDNEY	100	0
104	37	820 1980 PHARMACOLOGY & THERAPEUTICS 8(2):379-475 KULKARNI AP; HODGSON E METABOLISM OF INSECTICIDES BY MIXED-FUNCTION OXIDASE SYSTEMS	100	1
105	3	1078 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260(7):4007-4015 TAMBURINI PP; WHITE RE; SCHENKMAN JB CHEMICAL CHARACTERIZATION OF PROTEIN-PROTEIN INTERACTIONS BETWEEN CYTOCHROME-P-450 AND CYTOCHROME-B5	100	3
106	1	255 1972 LIFE SCIENCES PT-2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY 11(5):247-& SCHENKMAN JB; CINTI DL HEPATIC MIXED FUNCTION OXIDASE ACTIVITY IN RAPIDLY PREPARED MICROSOMES	99	9
107	6	379 1974 DRUG METABOLISM AND DISPOSITION 2(3):267-278 ELDEFRAW.S; COHEN GM; MANNERIN.GJ SEX-DEPENDENT DIFFERENCES IN DRUG-METABOLISM IN RAT .1. TEMPORAL CHANGES IN MICROSOMAL DRUG-METABOLIZING SYSTEM OF LIVER DURING SEXUAL-MATURATION	98	0
108	1	989 1983 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 19(1):1-10 GADHER P; MERCER EI; BALDWIN BC; WIGGINS TE A COMPARISON OF THE POTENCY OF SOME FUNGICIDES AS INHIBITORS OF STEROL 14-DEMETHYLATION	98	6
109	1	54 1969 JOURNAL OF BIOCHEMISTRY 65(2):269-& MITANI F; HORIE S STUDIES ON P-450 .V. ON SUBSTRATE-INDUCED SPECTRAL CHANGE OF P- 450 SOLUBILIZED FROM BOVINE ADRENOCORTICAL MITOCHONDRIA	97	21
110	1	789 1980 CHEMICO-BIOLOGICAL INTERACTIONS 29(3):277-289 PARKINSON A; COCKERLINE R; SAFE S POLYCHLORINATED BIPHENYL ISOMERS AND CONGENERS AS INDUCERS OF BOTH 3-METHYLCHOLANTHRENE-TYPE AND PHENOBARBITONE-TYPE MICROSOMAL-ENZYME ACTIVITY	97	0
111	6	1030 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259(24):5433-5439 MACGEOCH C; MORGAN ET; HALPERT J; GUSTAFSSON JA PURIFICATION, CHARACTERIZATION, AND PITUITARY REGULATION OF THE SEX-SPECIFIC CYTOCHROME-P-450 15-BETA-HYDROXYLASE FROM LIVER- MICROSOMES OF UNTREATED FEMALE RATS	97	0
112	2	649 1978 BIOCHEMICAL PHARMACOLOGY 27(7):1098-1101 ANDERS MW INHIBITION AND ENHANCEMENT OF MICROSOMAL DRUG-METABOLISM BY DIETHYL MALEATE	96	4
113	1	655 1978 BIOCHIMICA ET BIOPHYSICA ACTA 525(2):325-337 RICH PR; WIEGAND NK; BLUM H; MOORE AL; BONNER WD STUDIES ON MECHANISM OF INHIBITION OF REDOX ENZYMES BY SUBSTITUTED HYDROXAMIC ACIDS	96	0
114	8	133 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 145(2):531-& PETERSON JA; ULLRICH V; HILDEBRA.AG METYRAPONE INTERACTION WITH PSEUDOMONAS-PUTIDA CYTOCHEROME P- 450	95	21
115	4	58 1969 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 170(2):347-& STRIPP B; GREENE FE; GILLETTE JR DISULFIRAM IMPAIRMENT OF DRUG METABOLISM BY RAT LIVER MICROSOMES	94	4
116	5	329 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(7):2630-2633 HOLLENBE.PF; HAGER LP P-450 NATURE OF CARBON-MONOXIDE COMPLEX OF FERROUS CHLOROPEROXIDASE	94	0
117	2	584 1977 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 78(4):1254-1262 CEDERBAUM AI; DICKER E; RUBIN E; COHEN G EFFECT OF DIMETHYLSULFOXIDE AND OTHER HYDROXYL RADICAL SCAVENGERS ON OXIDATION OF ETHANOL BY RAT-LIVER MICROSOMES	94	1
118	2	35 1969 BIOCHEMICAL JOURNAL 113(4):681-& GRAM TE; GUARINO AM; SCHROEDE.DH; GILLETTE JR CHANGES IN CERTAIN KINETIC PROPERTIES OF HEPATIC MICROSOMAL ANILINE HYDROXYLASE AND ETHYLMORPHINE DEMETHYLASE ASSOCIATED WITH POSTNATAL DEVELOPMENT AND MATURATION IN MALE RATS	93	16
119	12	355 1974 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 160(1):230-245 HRYCAY EG; OBRIEN PJ MICROSOMAL ELECTRON-TRANSPORT .2. REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE-CYTOCHROME-B5 REDUCTASE AND CYTOCHROME-P-450 AS ELECTRON CARRIERS IN MICROSOMAL NADH-PEROXIDASE ACTIVITY	93	5
120	16	1365 1995 CRITICAL REVIEWS IN TOXICOLOGY 25(1):25-65 GOEPTAR AR; SCHEERENS H; VERMEULEN NPE OXYGEN AND XENOBIOTIC REDUCTASE ACTIVITIES OF CYTOCHROME-P450	93	1
121	1	175 1971 METABOLISM-CLINICAL AND EXPERIMENTAL 20(2):187-& ESTABROO.RW; FRANKLIN MR; COHEN B; SHIGAMAT.A; HILDEBRA.AG INFLUENCE OF HEPATIC MICROSOMAL MIXED FUNCTION OXIDATION REACTIONS ON CELLULAR METABOLIC CONTROL	92	0
122	7	348 1973 TOXICOLOGY AND APPLIED PHARMACOLOGY 26(3):398-406 GONASUN LM; WITMER C; KOCSIS JJ; SNYDER R BENZENE METABOLISM IN MOUSE LIVER-MICROSOMES	92	4
123	1	21 1968 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 163(2):417-& ALVARES AP; SCHILLIN.G; LEVIN W; KUNTZMAN R ALTERATION OF MICROSOMAL HEMOPROTEIN BY 3-METHYLCHOLANTHRENE - EFFECTS OF ETHIONINE AND ACTINOMYCIN D	91	17
124	6	337 1973 MOLECULAR PHARMACOLOGY 9(4):455-469 CORREIA MA; MANNERIN.GJ REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE SYNERGISM OF REDUCED TRIPHOSPHOPYRIDINE NUCLEOTIDE-DEPENDENT MIXED-FUNCTION OXIDASE SYSTEM OF HEPATIC MICROSOMES .1. EFFECTS OF ACTIVATION AND INHIBITION OF FATTY ACYL COENZYME A DESATURATION SYSTEM	91	15
125	3	391 1974 JOURNAL OF BIOLOGICAL CHEMISTRY 249(6):1940-1945 GUSTAFSS.JA; INGELMAN.M REGULATION AND PROPERTIES OF A SEX-SPECIFIC HYDROXYLASE SYSTEM IN FEMALE RAT-LIVER MICROSOMES ACTIVE ON STEROID SULFATES .1. GENERAL CHARACTERISTICS	91	0
126	4	664 1978 EUROPEAN JOURNAL OF BIOCHEMISTRY 88(1):37-47 FEYEREISEN R; DURST F ECDYSTERONE BIOSYNTHESIS - MICROSOMAL CYTOCHROME-P-450-LINKED ECDYSONE 20-MONOOXYGENASE FROM TISSUES OF AFRICAN MIGRATORY LOCUST	91	4
127	2	117 1970 LIFE SCIENCES PT-2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY 9(15):877-& HUTTERER F; DENK H; BACCHIN PG; SCKENKMA.JB; SCHAFFNE.F; POPPER H MECHANISM OF CHOLESTASIS .1. EFFECT OF BILE ACIDS ON MICROSOMAL CYTOCHROME-P-450 DEPENDENT BIOTRANSFORMATION SYSTEM IN-VITRO	90	14
128	3	474 1975 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 23(2):261-265 MEHENDALE HM; FIELDS M; MATTHEWS HB METABOLISM AND EFFECTS OF HEXACHLOROBENZENE ON HEPATIC MICROSOMAL-ENZYMES IN RAT	90	1
129	10	574 1977 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 178(1):89-107 JANSSON I; SCHENKMAN JB STUDIES ON 3 MICROSOMAL ELECTRON-TRANSFER ENZYME-SYSTEMS .2. SPECIFICITY OF ELECTRON FLOW PATHWAYS	90	6
130	1	595 1977 BIOCHEMICAL PHARMACOLOGY 26(22):2091-2094 BROWN BR; SIPES IG BIOTRANSFORMATION AND HEPATOTOXICITY OF HALOTHANE	90	0
131	1	159 1971 BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 6(2):120-& VILLENEU.DC; GRANT DL; PHILLIPS WE; CLARK ML; CLEGG DJ EFFECTS OF PCB ADMINISTRATION ON MICROSOMAL ENZYME ACTIVITY IN PREGNANT RABBITS	89	0
132	2	170 1971 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 176(1):11-& KUTT H; FOUTS JR DIPHENYLHYDANTOIN METABOLISM BY RAT LIVER MICROSOMES AND SOME OF EFFECTS OF DRUG OR CHEMICAL PRETREATMENT ON DIPHENYLHYDANTOIN METABOLISM BY RAT LIVER MICROSOMAL PREPARATIONS	89	7
133	4	446 1975 CANCER RESEARCH 35(2):382-389 GURTOO HL; DAVE CV INVITRO METABOLIC CONVERSION OF AFLATOXINS AND BENZO(A)PYRENE TO NUCLEIC ACID-BINDING METABOLITES	89	2
134	2	899 1982 CANCER RESEARCH 42(9):3747-3752 BOCK KW; LILIENBLUM W; PFEIL H; ERIKSSON LC INCREASED URIDINE DIPHOSPHATE-GLUCURONYLTRANSFERASE ACTIVITY IN PRENEOPLASTIC LIVER NODULES AND MORRIS HEPATOMAS	88	1
135	4	64 1969 MOLECULAR PHARMACOLOGY 5(4):412-& SHOEMAN DW; CHAPLIN MD; MANNERIN.GJ INDUCTION OF DRUG METABOLISM .3. FURTHER EVIDENCE FOR FORMATION OF A NEW P-450 HEMOPROTEIN AFTER TREATMENT OF RATS WITH 3- METHYLCHOLANTHRENE	87	39
136	3	44 1969 BIOCHIMICA ET BIOPHYSICA ACTA 171(1):23-& SCHENKMAN JB; GREIM H; ZANGE M; REMMER H ON PROBLEM OF POSSIBLE OTHER FORMS OF CYTOCHROME P450 IN LIVER MICROSOMES	86	56
137	1	235 1972 ENVIRONMENTAL RESEARCH 5(4):418-424 BAKER RC; COONS LB; MAILMAN RB; HODGSON E INDUCTION OF HEPATIC MIXED-FUNCTION OXIDASES BY INSECTICIDE, MIREX	86	12
138	3	736 1979 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 208(2):271-279 MARIETTA MP; VESELL ES; HARTMAN RD; WEISZ J; DVORCHIK BH CHARACTERIZATION OF CYTOCHROME P-450-DEPENDENT AMINOPYRINE N- DEMETHYLASE IN RAT-BRAIN - COMPARISON WITH HEPATIC AMINOPYRINE N-DEMETHYLATION	86	1
139	4	830 1981 ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE 251(1):26-38 NIEMEGEERS CJE; LEVRON JC; AWOUTERS F; JANSSEN PAJ INHIBITION AND INDUCTION OF MICROSOMAL-ENZYMES IN THE RAT - A COMPARATIVE-STUDY OF 4 ANTI-MYCOTICS - MICONAZOLE, ECONAZOLE, CLOTRIMAZOLE AND KETOCONAZOLE	86	7
140	2	1097 1986 ADVANCES IN MICROBIAL PHYSIOLOGY 27():1-72 KERRIDGE D MODE OF ACTION OF CLINICALLY IMPORTANT ANTIFUNGAL DRUGS	86	0
141	2	1377 1996 BIOCHEMISTRY 35(51):16735-16745 Gorren ACF; List BM; Schrammel A; Pitters E; Hemmens B; Werner ER; Schmidt K; Mayer B Tetrahydrobiopterin-free neuronal nitric oxide synthase: Evidence for two identical highly anticooperative pteridine binding sites	86	1
142	2	843 1981 BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN 54(4):1163-1170 WATANABE Y; NUMATA T; IYANAGI T; OAE S ENZYMATIC OXIDATION OF ALKYL SULFIDES BY CYTOCHROME-P-450 AND HYDROXYL RADICAL	85	0
143	4	139 1971 BIOCHEMICAL JOURNAL 123(4):539-& ELING TE; DIAUGUST.RP ROLE FOR PHOSPHOLIPIDS IN BINDING AND METABOLISM OF DRUGS BY HEPATIC MICROSOMES - USE OF FLUORESCENT HYDROPHOBIC PROBE 1- ANILINONAPHTHALENE-8-SULPHONATE	84	20
144	1	140 1971 BIOCHEMICAL JOURNAL 123(5):815-& SLATER TF; SAWYER BC STIMULATORY EFFECTS OF CARBON TETRACHLORIDE ON PEROXIDATIVE REACTIONS IN RAT LIVER FRACTIONS IN-VITRO - INTERACTION SITES IN ENDOPLASMIC RETICULUM	84	3
145	5	459 1975 DRUG METABOLISM AND DISPOSITION 3(2):104-112 KUBIC VL; ANDERS MW METABOLISM OF DIHALOMETHANES TO CARBON-MONOXIDE .2. INVITRO STUDIES	83	2
146	13	677 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253(17):5957-5963 GIBSON GG; SCHENKMAN JB PURIFICATION AND PROPERTIES OF CYTOCHROME-P-450 OBTAINED FROM LIVER-MICROSOMES OF UNTREATED RATS BY LAURIC ACID AFFINITY CHROMATOGRAPHY	83	13
147	4	1081 1985 MOLECULAR PHARMACOLOGY 27(4):471-479 MORGAN ET; MACGEOCH C; GUSTAFSSON JA SEXUAL-DIFFERENTIATION OF CYTOCHROME-P-450 IN RAT-LIVER - EVIDENCE FOR A CONSTITUTIVE ISOZYME AS THE MALE-SPECIFIC 16- ALPHA-HYDROXYLASE	83	3
148	2	1414 1997 NATURE BIOTECHNOLOGY 15(8):784-788 Parikh A; Gillam EMJ; Guengerich FP Drug metabolism by Escherichia coli expressing human cytochromes P450	83	2
149	2	50 1969 EUROPEAN JOURNAL OF BIOCHEMISTRY 11(1):193-& ORRENIUS S; BERG A; ERNSTER L EFFECTS OF TRYPSIN ON ELECTRON TRANSPORT SYSTEMS OF LIVER MICROSOMES	82	16
150	1	149 1971 BIOCHEMICAL PHARMACOLOGY 20(7):1569-& HANSEN LG; HODGSON E BIOCHEMICAL CHARACTERISTICS OF INSECT MICROSOMES - N- DEMETHYLATION AND O-DEMETHYLATION	82	3
151	3	219 1972 BIOCHEMISTRY 11(25):4740-& GRIFFIN BW; PETERSON JA CAMPHOR BINDING BY PSEUDOMONAS-PUTIDA CYTOCHROME-P-450 - KINETICS AND THERMODYNAMICS OF REACTION	82	13
152	1	247 1972 JOURNAL OF BIOLOGICAL CHEMISTRY 247(22):7232-& DEITRICH RA; ERWIN VG; COLLINS AC GENETIC INFLUENCE UPON PHENOBARBITAL-INDUCED INCREASE IN RAT- LIVER SUPERNATANT ALDEHYDE DEHYDROGENASE-ACTIVITY	82	0
153	5	478 1975 JOURNAL OF BIOLOGICAL CHEMISTRY 250(16):6445-6451 GRIFFIN BW; PETERSON JA PSEUDOMONAS-PUTIDA CYTOCHROME-P-450 - EFFECT OF COMPLEXES OF FERRIC HEMEPROTEIN ON RELAXATION OF SOLVENT WATER PROTONS	82	11
154	3	653 1978 BIOCHEMISTRY 17(15):3058-3064 CEDERBAUM AI; DICKER E; COHEN G EFFECT OF HYDROXYL RADICAL SCAVENGERS ON MICROSOMAL OXIDATION OF ALCOHOLS AND ON ASSOCIATED MICROSOMAL REACTIONS	82	0
155	4	317 1973 DRUG METABOLISM AND DISPOSITION 1(1):350-357 ORRENIUS S; ELLIN A; JAKOBSSO.SV; THOR H; CINTI DL; SCHENKMAN JB; ESTABROO.RW CYTOCHROME P-450-CONTAINING MONO-OXYGENASE SYSTEM OF RAT-KIDNEY CORTEX MICROSOMES	80	12
156	7	485 1975 MOLECULAR PHARMACOLOGY 11(4):450-461 JANSSON I; SCHENKMAN JB STUDIES ON 3 MICROSOMAL ELECTRON-TRANSFER ENZYME-SYSTEMS - EFFECTS OF ALTERATION OF COMPONENT ENZYME LEVELS INVIVO AND INVITRO	80	9
157	31	750 1979 PHARMACOLOGY & THERAPEUTICS 7(2):203-244 SNYDER R; REMMER H CLASSES OF HEPATIC MICROSOMAL MIXED-FUNCTION OXIDASE INDUCERS	80	5
158	4	921 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(8):4404-4411 JONEN HG; WERRINGLOER J; PROUGH RA; ESTABROOK RW THE REACTION OF PHENYLHYDRAZINE WITH MICROSOMAL CYTOCHROME-P- 450 - CATALYSIS OF HEME MODIFICATION	80	3
159	3	346 1973 TOXICOLOGY AND APPLIED PHARMACOLOGY 24(1):1-19 CASTRO JA; FERREYRA EC; CASTRO CRD; GOMEZ MID; DACOSTA N; FENOS OMD STUDIES ON MECHANISM OF CYSTAMINE PREVENTION OF SEVERAL LIVER STRUCTURAL AND BIOCHEMICAL ALTERATIONS CAUSED BY CARBON- TETRACHLORIDE	79	16
160	11	476 1975 JOURNAL OF BIOCHEMISTRY 78(3):455-468 YOSHIDA Y; KUMAOKA H STUDIES ON SUBSTRATE-INDUCED SPECTRAL CHANGE OF CYTOCHROME-P- 450 IN LIVER-MICROSOMES	79	40
161	2	1234 1989 JOURNAL OF MEDICINAL CHEMISTRY 32(10):2231-2239 VANWAUWE JP; JANSSEN PAJ IS THERE A CASE FOR P-450 INHIBITORS IN CANCER-TREATMENT	79	0
162	1	1256 1990 EUROPEAN JOURNAL OF BIOCHEMISTRY 194(3):889-896 RENAUD JP; CULLIN C; POMPON D; BEAUNE P; MANSUY D EXPRESSION OF HUMAN LIVER CYTOCHROME-P450 IIIA4 IN YEAST - A FUNCTIONAL-MODEL FOR THE HEPATIC ENZYME	79	2
163	5	249 1972 JOURNAL OF NUTRITION 102(1):53-& MGBODILE MU; CAMPBELL TC EFFECT OF PROTEIN DEPRIVATION OF MALE WEANLING RATS ON KINETICS OF HEPATIC MICROSOMAL ENZYME-ACTIVITY	78	0
164	1	541 1976 GANN 67(6):899-902 OKITA K; NODA K; FUKUMOTO Y; TAKEMOTO T CYTOCHROME-P-450 IN HYPERPLASTIC LIVER NODULES DURING HEPATOCARCINOGENESIS WITH N-2-FLUORENYLACETAMIDE IN RATS	78	0
165	4	650 1978 BIOCHEMICAL PHARMACOLOGY 27(8):1203-1209 LESCA P; LECOINTE P; PAOLETTI C; MANSUY D ELLIPTICINES AS POTENT INHIBITORS OF ARYL-HYDROCARBON HYDROXYLASE - THEIR BINDING TO MICROSOMAL CYTOCHROMES P450 AND PROTECTIVE EFFECT AGAINST BENZO(A)PYRENE MUTAGENICITY	78	9
166	5	642 1978 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 186(1):128-138 FANG WF; STROBEL HW DRUG AND CARCINOGEN METABOLISM SYSTEM OF RAT COLON MICROSOMES	77	1
167	3	63 1969 MOLECULAR PHARMACOLOGY 5(2):123-& SASAME HA; GILLETTE JR STUDIES ON RELATIONSHIP BETWEEN EFFECTS OF VARIOUS SUBSTANCES ON ABSORPTION SPECTRUM OF CYTOCHROME P-450 AND REDUCTION OF P- NITROBENZOATE BY MOUSE LIVER MICROSOMES	76	27
168	3	1160 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262(29):14319-14326 FAVREAU LV; MALCHOFF DM; MOLE JE; SCHENKMAN JB RESPONSES TO INSULIN BY 2 FORMS OF RAT HEPATIC-MICROSOMAL CYTOCHROME-P-450 THAT UNDERGO MAJOR (RLM6) AND MINOR (RLM5B) ELEVATIONS IN DIABETES	76	3
169	1	1305 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 294(2):454-460 VINCENT SH; KARANAM BV; PAINTER SK; CHIU SHL INVITRO METABOLISM OF FK-506 IN RAT, RABBIT, AND HUMAN LIVER- MICROSOMES - IDENTIFICATION OF A MAJOR METABOLITE AND OF CYTOCHROME P450-3A AS THE MAJOR ENZYMES RESPONSIBLE FOR ITS METABOLISM	76	1
170	4	142 1971 BIOCHEMICAL PHARMACOLOGY 20(1):229-& RUBIN E; LIEBER CS; ALVARES AP; LEVIN W; KUNTZMAN R ETHANOL BINDING TO HEPATIC MICROSOMES - ITS INCREASE BY ETHANOL CONSUMPTION	74	12
171	9	555 1976 LIFE SCIENCES 19(5):611-623 SCHENKMAN JB; JANSSON I; ROBIESUH KM MANY ROLES OF CYTOCHROME-B5 IN HEPATIC MICROSOMES	73	6
172	10	562 1976 TOXICOLOGY 5(3):297-309 LAKE BG; PHILLIPS JC; HEADING CE; GANGOLLI SD STUDIES ON INVITRO METABOLISM OF DIMETHYLNITROSAMINE BY RAT- LIVER	73	8
173	7	256 1972 MOLECULAR PHARMACOLOGY 8(2):178-& SCHENKMAN JB EFFECTS OF TEMPERATURE AND SUBSTRATES ON COMPONENT REACTIONS OF HEPATIC MICROSOMAL MIXED-FUNCTION OXIDASE	72	13
174	7	285 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 157(1):148-159 NEBERT DW; CONSIDIN.N; OWENS IS GENETIC EXPRESSION OF ARYL HYDROCARBON HYDROXYLASE INDUCTION .6. CONTROL OF OTHER AROMATIC HYDROCARBON-INDUCIBLE MONO- OXYGENASE ACTIVITIES AT OR NEAR SAME GENETIC LOCUS	72	2
175	1	463 1975 EUROPEAN JOURNAL OF BIOCHEMISTRY 55(2):333-341 RICH PR; BENDALL DS CYTOCHROME COMPONENTS OF PLANT MICROSOMES	72	3
176	4	752 1979 PHYSIOLOGICAL REVIEWS 59(2):353-406 FINKELSTEIN M; SHAEFER JM INBORN-ERRORS OF STEROID-BIOSYNTHESIS	72	0
177	4	923 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(10):5496-5502 SONO M; DAWSON JH FORMATION OF LOW-SPIN COMPLEXES OF FERRIC CYTOCHROME P-450-CAM WITH ANIONIC LIGANDS - SPIN STATE AND LIGAND AFFINITY COMPARISON TO MYOGLOBIN	72	3
178	16	1156 1987 DRUG METABOLISM REVIEWS 18(1):55-81 MURRAY M MECHANISMS OF THE INHIBITION OF CYTOCHROME-P-450-MEDIATED DRUG OXIDATION BY THERAPEUTIC AGENTS	72	6
179	7	67 1969 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 265(3):205-& NETTER KJ; KAHL GF; MAGNUSSE.MP KINETIC EXPERIMENTS ON BINDING OF METYRAPONE TO LIVER MICROSOMES	71	19
180	2	121 1970 MOLECULAR PHARMACOLOGY 6(4):391-& JEFCOATE CR; CALABRES.RL; GAYLOR JL LIGAND INTERACTION WITH HEMOPROTEIN P-450 .3. USE OF NORMAL- OCTYLAMINE AND ETHYL ISOCYANIDE DIFFERENCE SPECTROSCOPY IN QUANTITATIVE DETERMINATION OF HIGH-SPIN AND LOW-SPIN P-450	71	0
181	2	358 1974 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 57(2):426-433 MAY HE; BOOSE R; REED DJ HYDROXYLATION OF CARCINOSTATIC 1-(2-CHLOROETHYL)-3-CYCLOHEXYL- 1-NITROSOUREA (CCNU) BY RAT-LIVER MICROSOMES	71	2
182	3	360 1974 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 61(2):735-742 GURTOO HL; BEJBA N HEPATIC MICROSOMAL MIXED-FUNCTION OXYGENASE - ENZYME MULTIPLICITY FOR METABOLISM OF CARCINOGENS TO DNA-BINDING METABOLITES	71	0
183	2	430 1975 BIOCHEMICAL PHARMACOLOGY 24(15):1427-1433 ELCOMBE CR; BRIDGES JW; GRAY TJB; NIMMOSMITH RH; NETTER KJ STUDIES ON INTERACTION OF SAFROLE WITH RAT HEPATIC MICROSOMES	71	9
184	11	380 1974 DRUG METABOLISM AND DISPOSITION 2(3):301-308 MAILMAN RB; KULKARNI AP; BAKER RC; HODGSON E CYTOCHROME-P-450 DIFFERENCE SPECTRA - EFFECT OF CHEMICAL- STRUCTURE ON TYPE-II SPECTRA IN MOUSE HEPATIC MICROSOMES	70	34
185	2	1353 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(42):26083-26091 FREY C; NARAYANAN K; MCMILLAN K; SPACK L; GROSS SS; MASTERS BS; GRIFFITH OW L-THIOCITRULLINE - A STEREOSPECIFIC, HEME-BINDING INHIBITOR OF NITRIC-OXIDE SYNTHASES	70	3
186	3	52 1969 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 350(5):547-& DEGKWITZ E; ULLRICH V; STAUDING.H; RUMMEL W METABOLISM AND CYTOCHROME P-450 BINDING SPECTRA OF (+)- AND (- )-HEXOBARBITAL IN RAT LIVER MICROSOMES	69	20
187	4	288 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 158(2):597-604 ELLIN A; ORRENIUS S CYTOCHROME P-450K OF RAT-KIDNEY CORTEX MICROSOMES - FURTHER STUDIES ON ITS INTERACTION WITH FATTY-ACIDS	69	7
188	5	556 1976 MOLECULAR PHARMACOLOGY 12(2):322-334 SUGIURA M; IWASAKI K; KATO R REDUCTION OF TERTIARY AMINE N-OXIDES BY LIVER MICROSOMAL CYTOCHROME-P-450	69	6
189	1	724 1979 DRUG METABOLISM AND DISPOSITION 7(5):260-262 RICE SA; TALCOTT RE EFFECTS OF ISONIAZID TREATMENT ON SELECTED HEPATIC MIXED- FUNCTION OXIDASES	69	1
190	6	194 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 151(2):391-& JANSSON I; SCHENKMAN JB; ERNSTER L; ORRENIUS S STUDY OF INTERACTION OF A SERIES OF SUBSTITUTED BARBITURIC ACIDS WITH HEPATIC MICROSOMAL MONOOXYGENASE	68	32
191	10	284 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 157(1):7-22 HRYCAY EG; OBRIEN PJ MICROSOMAL ELECTRON-TRANSPORT .1. REDUCED NICOTINAMIDE ADENINE- DINUCLEOTIDE PHOSPHATE-CYTOCHROME-C REDUCTASE AND CYTOCHROME-P- 450 AS ELECTRON CARRIERS IN MICROSOMAL NADPH-PEROXIDASE ACTIVITY	68	6
192	9	198 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 153(2):543-553 LEVIN W; LU AYH; RYAN D; WEST S; KUNTZMAN R; CONNEY AH PARTIAL-PURIFICATION AND PROPERTIES OF CYTOCHROMES P-450 AND P- 448 FROM RAT-LIVER MICROSOMES	67	4
193	1	1236 1989 MARINE ENVIRONMENTAL RESEARCH 27(1):51-65 WATANABE S; SHIMADA T; NAKAMURA S; NISHIYAMA N; YAMASHITA N; TANABE S; TATSUKAWA R SPECIFIC PROFILE OF LIVER MICROSOMAL CYTOCHROME-P-450 IN DOLPHIN AND WHALES	67	0
194	5	336 1973 MOLECULAR PHARMACOLOGY 9(3):383-397 COHEN GM; MANNERIN.GJ INVOLVEMENT OF A HYDROPHOBIC SITE IN INHIBITION OF MICROSOMAL PARA-HYDROXYLATION OF ANILINE BY ALCOHOLS	66	12
195	1	113 1970 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 174(2):197-& CATZ CS; JUCHAU MR; YAFFE SJ EFFECTS OF IRON, RIBOFLAVIN AND IODIDE DEFICIENCIES ON HEPATIC DRUG-METABOLIZING ENZYME SYSTEMS	65	11
196	4	201 1972 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 47(3):611-& KUPFER D; LEVIN E MONOOXYGENASE DRUG-METABOLIZING ACTIVITY IN CACL2-AGGREGATED HEPATIC MICROSOMES FROM RAT-LIVER	65	3
197	3	934 1982 XENOBIOTICA 12(1):9-17 RENDIC S; ALEBICKOLBAH T; KAJFEZ F; RUF HH INTERACTION OF RANITIDINE WITH LIVER-MICROSOMES	65	4
198	4	103 1970 JAPANESE JOURNAL OF PHARMACOLOGY 20(4):546-& KATO R; ONODA KI; TAKANAKA A SPECIES DIFFERENCE IN DRUG METABOLISM BY LIVER MICROSOMES IN ALLOXAN DIABETIC OR FASTED ANIMALS .1. ACTIVITY OF DRUG- METABOLIZING ENZYMES AND ELECTRON TRANSPORT SYSTEM	64	5
199	5	176 1971 METABOLISM-CLINICAL AND EXPERIMENTAL 20(2):215-& GILLETTE JR EFFECT OF VARIOUS INDUCERS ON ELECTRON TRANSPORT SYSTEM ASSOCIATED WITH DRUG METABOLISM BY LIVER MICROSOMES	64	10
200	5	394 1974 JOURNAL OF PEDIATRICS 85(4):534-542 ARANDA JV; MACLEOD SM; RENTON KW; EADE NR HEPATIC MICROSOMAL DRUG OXIDATION AND ELECTRON-TRANSPORT IN NEWBORN-INFANTS	64	3

#	Cited nodes	Nodes / Authors	GCS	LCS
201	2	512 1976 BIOCHEMICAL PHARMACOLOGY 25(3):329-335 KHANNA JM; KALANT H; YEE Y; CHUNG S; SIEMENS AJ EFFECT OF CHRONIC ETHANOL TREATMENT ON METABOLISM OF DRUGS INVITRO AND INVIVO	64	2
202	3	565 1976 TOXICOLOGY AND APPLIED PHARMACOLOGY 38(1):71-77 FABACHER DL; HODGSON E INDUCTION OF HEPATIC MIXED-FUNCTION OXIDASE ENZYMES IN ADULT AND NEONATAL MICE BY KEPONE AND MIREX	64	8
203	2	45 1969 BIOCHIMICA ET BIOPHYSICA ACTA 171(1):32-& ICHIKAWA Y; YAMANO T; FUJISHIM.H RELATIONSHIP BETWEEN INTERCONVERSION OF CYTOCHROME P-450 AND P- 420 AND ITS ACTIVITIES IN HYDROXYLATIONS AND DEMETHYLATIONS BY P-450 OXIDASE SYSTEMS	63	11
204	6	447 1975 CANCER RESEARCH 35(8):2083-2091 VADI H; MOLDEUS P; CAPDEVILA J; ORRENIUS S METABOLISM OF BENZO(ALPHA-)PYRENE IN ISOLATED RAT-LIVER CELLS	63	2
205	13	675 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253(11):3888-3897 EBEL RE; OKEEFFE DH; PETERSON JA SUBSTRATE BINDING TO HEPATIC MICROSOMAL CYTOCHROME-P-450 - INFLUENCE OF MICROSOMAL MEMBRANE	63	25
206	2	109 1970 JOURNAL OF BIOLOGICAL CHEMISTRY 245(16):4187-& HILTON J; SARTOREL.AC INDUCTION BY PHENOBARBITAL OF MICROSOMAL MIXED OXIDASE ENZYMES IN REGENERATING RAT LIVER	62	2
207	7	110 1970 JOURNAL OF BIOLOGICAL CHEMISTRY 245(20):5441-& WHYSNER JA; RAMSEYER J; HARDING BW SUBSTRATE-INDUCED CHANGES IN VISIBLE ABSORPTION AND ELECTRON SPIN RESONANCE PROPERTIES OF ADRENAL CORTEX MITOCHONDRIAL-P450	62	15
208	7	120 1970 MOLECULAR PHARMACOLOGY 6(3):221-& KUPFER D; ORRENIUS S CHARACTERISTICS OF GUINEA-PIG LIVER AND ADRENAL MONOOXYGENASE SYSTEMS	62	19
209	4	319 1973 DRUG METABOLISM REVIEWS 2(1):1-32 GRAM TE COMPARATIVE ASPECTS OF MIXED-FUNCTION OXIDATION BY LUNG AND LIVER OF RABBITS	62	4
210	6	72 1970 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 39(6):1073-& JAKOBSSO.S FATTY ACID INDUCIBLE CYTOCHROME P-454 OF RAT KIDNEY CORTEX MICROSOMES	61	0
211	5	292 1973 BIOCHEMICAL JOURNAL 134(2):367-375 CINTI DL; GRUNDIN R; ORRENIUS S EFFECT OF ETHANOL ON DRUG OXIDATIONS IN-VITRO AND SIGNIFICANCE OF ETHANOL-CYTOCHROME P-450 INTERACTION	61	10
212	21	751 1979 PHARMACOLOGY & THERAPEUTICS 7(3):549-599 BURKE MD; ORRENIUS S ISOLATION AND COMPARISON OF ENDOPLASMIC-RETICULUM MEMBRANES AND THEIR MIXED-FUNCTION OXIDASE ACTIVITIES FROM MAMMALIAN EXTRA- HEPATIC TISSUES	61	0
213	3	1348 1994 EUROPEAN JOURNAL OF BIOCHEMISTRY 222(3):843-850 URBAN P; WERCKREICHHART D; TEUTSCH HG; DURST F; REGNIER S; KAZMAIER M; POMPON D CHARACTERIZATION OF RECOMBINANT PLANT CINNAMATE 4-HYDROXYLASE PRODUCED IN YEAST - KINETIC AND SPECTRAL PROPERTIES OF THE MAJOR PLANT P450 OF THE PHENYLPROPANOID PATHWAY	61	0
214	2	126 1971 ACTA PHARMACOLOGICA ET TOXICOLOGICA 29(2-3):284-& PELKONEN O; VORNE M; JOUPPILA P; KARKI NT METABOLISM OF CHLORPROMAZINE AND PARA NITROBENZOIC ACID IN LIVER, INTESTINE AND KIDNEY OF HUMAN FOETUS	60	2
215	6	328 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(6):2192-2201 FUJITA T; SHOEMAN DW; MANNERIN.GJ DIFFERENCES IN P-450 CYTOCHROMES FROM LIVERS OF RATS TREATED WITH PHENOBARBITAL AND WITH 3-METHYLCHOLANTHRENE	60	11
216	2	1067 1985 CANCER RESEARCH 45(8):3573-3577 STEELE CM; LALIES M; IOANNIDES C INHIBITION OF THE MUTAGENICITY OF AROMATIC-AMINES BY THE PLANT FLAVONOID (+)-CATECHIN	60	0
217	2	1314 1992 CARCINOGENESIS 13(1):95-100 KENSLER TW; GROOPMAN JD; EATON DL; CURPHEY TJ; ROEBUCK BD POTENT INHIBITION OF AFLATOXIN-INDUCED HEPATIC TUMORIGENESIS BY THE MONOFUNCTIONAL ENZYME INDUCER 1,2-DITHIOLE-3-THIONE	60	0
218	2	115 1970 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 175(1):12-& GRAM TE; GUARINO AM; SCHROEDE.DH; DAVIS DC; REAGAN RL; GILLETTE JR EFFECT OF STARVATION ON KINETICS OF DRUG OXIDATION BY HEPATIC MICROSOMAL ENZYMES FROM MALE AND FEMALE RATS	59	8
219	1	225 1972 CANCER CHEMOTHERAPY REPORTS PART 1 56(5):603-610 ALLEN LM; CREAVEN PJ IN-VITRO ACTIVATION OF ISOPHOSPHAMIDE (NSC-109724), A NEW OXAZAPHOSPHORINE, BY RAT-LIVER MICROSOMES	59	4
220	1	271 1972 TOXICOLOGY AND APPLIED PHARMACOLOGY 22(1):50-& CHHABRA RS; FOUTS JR; GRAM TE COMPARATIVE STUDY OF 2 PROCEDURES USED IN DETERMINATION OF HEPATIC MICROSOMAL ANILINE HYDROXYLATION	59	8
221	8	717 1979 BIOCHEMISTRY 18(1):36-42 CINTI DL; SLIGAR SG; GIBSON GG; SCHENKMAN JB TEMPERATURE-DEPENDENT SPIN EQUILIBRIUM OF MICROSOMAL AND SOLUBILIZED CYTOCHROME-P-450 FROM RAT-LIVER	59	24
222	3	1103 1986 BIOCHEMICAL PHARMACOLOGY 35(11):1867-1878 LAVRIJSEN K; VANHOUDT J; THIJS D; MEULDERMANS W; HEYKANTS J INDUCTION POTENTIAL OF ANTIFUNGALS CONTAINING AN IMIDAZOLE OR TRIAZOLE MOIETY - MICONAZOLE AND KETOCONAZOLE, BUT NOT ITRACONAZOLE ARE ABLE TO INDUCE HEPATIC DRUG-METABOLIZING- ENZYMES OF MALE-RATS AT HIGH-DOSES	59	0
223	3	1293 1991 MOLECULAR PHARMACOLOGY 39(3):275-280 RAUCY JL; LASKER JM; KRANER JC; SALAZAR DE; LIEBER CS; CORCORAN GB INDUCTION OF CYTOCHROME-P450IIE1 IN THE OBESE OVERFED RAT	59	0
224	9	338 1973 MOLECULAR PHARMACOLOGY 9(4):470-485 CORREIA MA; MANNERIN.GJ REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE SYNERGISM OF REDUCED TRIPHOSPHOPYRIDINE NUCLEOTIDE-DEPENDENT MIXED-FUNCTION OXIDASE SYSTEM OF HEPATIC MICROSOMES .2. ROLE OF TYPE 1 DRUG-BINDING SITE OF CYTOCHROME-P-450	58	7
225	16	928 1982 PHARMACOLOGY & THERAPEUTICS 16(3):377-429 KLINGER W BIOTRANSFORMATION OF DRUGS AND OTHER XENOBIOTICS DURING POSTNATAL-DEVELOPMENT	58	2
226	3	78 1970 BIOCHEMICAL PHARMACOLOGY 19():1025-& SASAME HA; GILLETTE JR STUDIES ON INHIBITORY EFFECTS OF VARIOUS SUBSTANCES ON DRUG METABOLISM BY LIVER MICROSOMES - EFFECT OF NICOTINAMIDE IN ALTERING APPARENT MECHANISM OF INHIBITION	57	17
227	4	95 1970 EUROPEAN JOURNAL OF BIOCHEMISTRY 15(3):531-& SIES H; BRAUSER B INTERACTION OF MIXED FUNCTION OXIDASE WITH ITS SUBSTRATES AND ASSOCIATED REDOX TRANSITIONS OF CYTOCHROME-P-450 AND PYRIDINE NUCLEOTIDES IN PERFUSED RAT LIVER	57	7
228	2	282 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):406-419 MASON JI; ESTABROO.RW; PURVIS JL TESTICULAR CYTOCHROME-P-450 AND IRON-SULFUR PROTEIN AS RELATED TO STEROID METABOLISM	57	3
229	6	293 1973 BIOCHEMICAL PHARMACOLOGY 22(9):1005-1014 HAYES JR; MGBODILE MU; CAMPBELL TC EFFECT OF PROTEIN-DEFICIENCY ON INDUCIBILITY OF HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM .1. EFFECT ON SUBSTRATE INTERACTION WITH CYTOCHROME-P-450	57	6
230	3	803 1980 INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 37(6):621-631 YUKAWA O; NAKAZAWA T RADIATION-INDUCED LIPID-PEROXIDATION AND MEMBRANE-BOUND ENZYMES IN LIVER-MICROSOMES	57	2
231	4	987 1983 MUTATION RESEARCH 116(3-4):257-269 HAUGEN DA; PEAK MJ MIXTURES OF POLYCYCLIC AROMATIC-COMPOUNDS INHIBIT MUTAGENESIS IN THE SALMONELLA MICROSOME ASSAY BY INHIBITION OF METABOLIC- ACTIVATION	57	0
232	5	428 1975 BIOCHEMICAL PHARMACOLOGY 24(3):369-378 LIU SJ; RAMSEY RK; FALLON HJ EFFECTS OF ETHANOL ON HEPATIC MICROSOMAL DRUG-METABOLIZING- ENZYMES IN RAT	56	3
233	4	623 1977 JOURNAL OF BIOCHEMISTRY 82(5):1237-1246 IMAI Y; SATO R; IYANAGI T RATE-LIMITING STEP IN RECONSTITUTED MICROSOMAL DRUG HYDROXYLASE SYSTEM	56	6
234	12	832 1981 BIOCHEMICAL PHARMACOLOGY 30(6):595-600 MORGAN ET; DEVINE M; SKETT P CHANGES IN THE RAT HEPATIC MIXED-FUNCTION OXIDASE SYSTEM ASSOCIATED WITH CHRONIC ETHANOL VAPOR INHALATION	56	5
235	3	85 1970 BIOCHEMICAL PHARMACOLOGY 19(8):2461-& CASTRO JA; GREENE FE; GIGON P; SASAME H; GILLETTE JR EFFECT OF ADRENALECTOMY AND CORTISONE ADMINISTRATION ON COMPONENTS OF LIVER MICROSOMAL MIXED FUNCTION OXYGENASE SYSTEM OF MALE RATS WHICH CATALYZES ETHYLMORPHINE METABOLISM	55	4
236	1	361 1974 BIOCHEMICAL PHARMACOLOGY 23(2):295-& CASTRO JA; FERREYRA EC; CASTRO CRD; FENOS OMD; SASAME H; GILLETTE JR PREVENTION OF CARBON TETRACHLORIDE-INDUCED NECROSIS BY INHIBITORS OF DRUG-METABOLISM - FURTHER STUDIES ON THEIR MECHANISM OF ACTION	55	1
237	8	425 1975 BIOCHEMICAL JOURNAL 148(2):269-277 POWIS G EFFECT OF A SINGLE ORAL DOSE OF METHANOL, ETHANOL AND PROPAN-2- OL ON HEPATIC MICROSOMAL METABOLISM OF FOREIGN COMPOUNDS IN RAT	55	8
238	2	787 1980 CANCER RESEARCH 40(9):3241-3244 FARRELLY JG A NEW ASSAY FOR THE MICROSOMAL METABOLISM OF NITROSAMINES	55	0
239	3	883 1982 BIOCHEMICAL PHARMACOLOGY 31(7):1393-1400 JORDAN RA; SCHENKMAN JB RELATIONSHIP BETWEEN MALONDIALDEHYDE PRODUCTION AND ARACHIDONATE CONSUMPTION DURING NADPH-SUPPORTED MICROSOMAL LIPID-PEROXIDATION	55	2
240	5	108 1970 JOURNAL OF BIOLOGICAL CHEMISTRY 245(3):519-& NEBERT DW MICROSOMAL CYTOCHROMES B5 AND P450 DURING INDUCTION OF ARYL HYDROCARBON HYDROXYLASE ACTIVITY IN MAMMALIAN CELL CULTURE	54	6
241	2	254 1972 KIDNEY INTERNATIONAL 2(3):152-& LEBER HW; SCHUTTER.G OXIDATIVE DRUG-METABOLISM IN LIVER-MICROSOMES FROM UREMIC RATS	54	0
242	3	397 1974 LIFE SCIENCES 15(8):1433-1442 SUGIURA M; IWASAKI K; NOGUCHI H; KATO R EVIDENCE FOR INVOLVEMENT OF CYTOCHROME-P-450 IN TIARAMIDE N- OXIDE REDUCTION	54	5
243	7	741 1979 MOLECULAR AND CELLULAR BIOCHEMISTRY 24(1):21-43 MITANI F CYTOCHROME-P450 IN ADRENOCORTICAL MITOCHONDRIA	54	1
244	3	949 1983 BIOCHEMICAL PHARMACOLOGY 32(5):831-835 REILLY PEB; CARRINGTON LE; WINZOR DJ THE INTERACTION OF CIMETIDINE WITH RAT-LIVER MICROSOMES	54	9
245	11	981 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258(22):3637-3645 DAWSON JH; ANDERSSON LA; SONO M THE DIVERSE SPECTROSCOPIC PROPERTIES OF FERROUS CYTOCHROME-P- 450-CAM LIGAND COMPLEXES	54	0
246	3	37 1969 BIOCHEMICAL JOURNAL 115(3):547-& DIAUGUST.RP; FOUTS JR EFFECTS OF UNSATURATED FATTY ACIDS ON HEPATIC MICROSOMAL DRUG METABOLISM AND CYTOCHROME P-450	53	0
247	3	136 1971 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 42(1):1-& RUBIN E; GANG H; LIEBER CS INTERACTION OF ETHANOL AND PYRAZOLE WITH HEPATIC MICROSOMES	53	3
248	6	258 1972 MOLECULAR PHARMACOLOGY 8(2):204-& PHILPOT RM; HODGSON E EFFECT OF PIPERONYL BUTOXIDE CONCENTRATION ON FORMATION OF CYTOCHROME-P-450 DIFFERENCE SPECTRA IN HEPATIC MICROSOMES FROM MICE	53	12
249	6	314 1973 CLINICAL PHARMACOLOGY & THERAPEUTICS 14(4):666-672 RANE A; SJOQVIST F; ORRENIUS S DRUGS AND FETAL METABOLISM	53	2
250	7	316 1973 DRUG METABOLISM AND DISPOSITION 1(1):111-120 SCHENKMAN JB; CINTI DL; MOLDEUS PW; ORRENIUS S NEWER ASPECTS OF SUBSTRATE BINDING TO CYTOCHROME-P-450	53	33
251	5	521 1976 BIOCHEMICAL PHARMACOLOGY 25(24):2747-2750 HOLDER GM; LITTLE PJ; RYAN AJ; WATSON TR INHIBITORS OF HEPATIC MIXED-FUNCTION OXIDASES .2. SOME BENZIMIDAZOLE, BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES	53	10
252	5	1031 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259(9):5776-5783 VANROLLINS M; BAKER RC; SPRECHER HW; MURPHY RC OXIDATION OF DOCOSAHEXAENOIC ACID BY RAT-LIVER MICROSOMES	53	0
253	4	1130 1986 MICROBIOLOGICAL REVIEWS 50(3):244-258 KAPPELI O CYTOCHROMES-P-450 OF YEASTS	53	0
254	5	1310 1992 BIOCHEMICAL PHARMACOLOGY 44(2):251-259 WALTON MI; WOLF CR; WORKMAN P THE ROLE OF CYTOCHROME-P450 AND CYTOCHROME-P450 REDUCTASE IN THE REDUCTIVE BIOACTIVATION OF THE NOVEL BENZOTRIAZINE DI-N- OXIDE HYPOXIC CYTOTOXIN 3-AMINO-1,2,4-BENZOTRIAZINE-1,4-DIOXIDE (SR-4233, WIN-59075) BY MOUSE-LIVER	53	0
255	3	1449 2000 BIOCHEMISTRY 39(20):5929-5939 Hosea NA; Miller GP; Guengerich FP Elucidation of distinct ligand binding sites for cytochrome P450 3A4	53	3
256	1	15 1968 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 349(11):1610-& GUNSALUS IC A SOLUBLE METHYLENE HYDROXYLASE SYSTEM - STRUCTURE AND ROLE OF CYTOCHROME P-450 AND IRON-SULFUR PROTEIN COMPONENTS	52	11
257	1	42 1969 BIOCHEMISTRY 8(4):1306-& WILLIAMS.DG; ODONNELL VJ INTERACTION OF METOPIRONE WITH ADRENAL MITOCHONDRIAL CYTOCHROME P-450 . A MECHANISM FOR INHIBITION OF ADRENAL STEROID 11BETA- HYDROXYLATION	52	0
258	1	77 1970 BIOCHEMICAL PHARMACOLOGY 19(3):895-& BECKING GC; MORRISON AB HEPATIC DRUG METABOLISM IN ZINC-DEFICIENT RATS	52	5
259	3	208 1972 BIOCHEMICAL PHARMACOLOGY 21(15):2053-& JUCHAU MR; SYMMS KG ANILINE HYDROXYLATION IN HUMAN PLACENTA - MECHANISTIC ASPECTS	52	4
260	7	674 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253(8):2804-2811 KUPFER D; NAVARRO J; PICCOLO DE HYDROXYLATION OF PROSTAGLANDINS-A1 AND E1 BY LIVER MICROSOMAL MONO-OXYGENASE - CHARACTERISTICS OF ENZYME-SYSTEM IN GUINEA-PIG	52	9
261	7	731 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(13):5641-5646 WOOD AW GENETIC-REGULATION OF COUMARIN HYDROXYLASE-ACTIVITY IN MICE - BIOCHEMICAL CHARACTERIZATION OF THE ENZYME FROM 2 INBRED STRAINS AND THEIR F1-HYBRID	52	3
262	2	773 1980 BIOCHEMICAL JOURNAL 188(3):937-939 PAINE AJ; VILLA P; HOCKIN LJ EVIDENCE THAT LIGAND FORMATION IS A MECHANISM UNDERLYING THE MAINTENANCE OF CYTOCHROME-P-450 IN RAT-LIVER CELL-CULTURE - POTENT MAINTENANCE BY METYRAPONE	52	0
263	1	837 1981 BIOCHIMICA ET BIOPHYSICA ACTA 646(2):283-297 MEIER PJ; SPYCHER MA; MEYER UA ISOLATION AND CHARACTERIZATION OF ROUGH ENDOPLASMIC-RETICULUM ASSOCIATED WITH MITOCHONDRIA FROM NORMAL RAT-LIVER	52	0
264	2	34 1969 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 36(5):789-& LEIBMAN KC; HILDEBRA.AG; ESTABROO.RW SPECTROPHOTOMETRIC STUDIES OF INTERACTIONS BETWEEN VARIOUS SUBSTRATES IN THEIR BINDING TO MICROSOMAL CYTOCHROME P-450	51	23
265	3	73 1970 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 40(4):858-& LIEBER CS; RUBIN E; DECARLI LM HEPATIC MICROSOMAL ETHANOL OXIDIZING SYSTEM (MEOS) - DIFFERENTIATION FROM ALCOHOL DEHYDROGENASE AND NADPH OXIDASE	51	2
266	2	557 1976 MUTATION RESEARCH 35(3):415-422 GUTTENPLAN JB; HUTTERER F; GARRO AJ EFFECTS OF CYTOCHROME P-448 AND P-450 INDUCERS ON MICROSOMAL DIMETHYLNITROSAMINE DEMETHYLASE ACTIVITY AND CAPACITY OF ISOLATED MICROSOMES TO ACTIVATE DIMETHYLNITROSAMINE TO A MUTAGEN	51	2
267	9	195 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 153(1):294-& LU AYH; LEVIN W; WEST SB; KUNTZMAN R; JACOBSON M RECONSTITUTED LIVER MICROSOMAL ENZYME-SYSTEM THAT HYDROXYLATES DRUGS, OTHER FOREIGN COMPOUNDS, AND ENDOGENOUS SUBSTRATES .4. HYDROXYLATION OF ANILINE	50	9
268	1	301 1973 BIOCHIMICA ET BIOPHYSICA ACTA 309(1):67-74 ZAKIM D; GOLDENBE.J; VESSEY DA DIFFERENTIATION OF HOMOLOGOUS FORMS OF HEPATIC MICROSOMAL UDP- GLUCURONYLTRANSFERASE .1. EVIDENCE FOR GLUCURONIDATION OF ORTHO-AMINOPHENOL AND PARA-NITROPHENOL BY SEPARATE ENZYMES	50	1
269	3	335 1973 LABORATORY INVESTIGATION 28(3):321-331 SCHAFFNE.F; SCHARNBE.HH; HUTTERER F; DENK H; GREIM HA; POPPER H MECHANISM OF CHOLESTASIS .7. ALPHA-NAPHTHYLISOTHIOCYANATE- INDUCED JAUNDICE	50	0
270	1	597 1977 BIOCHEMICAL PHARMACOLOGY 26(22):2169-2173 LESCA P; LECOINTE P; PAOLETTI C; MANSUY D HYDROXYLATION OF ANTI-TUMOR AGENT, ELLIPTICINE, BY LIVER- MICROSOMES FROM DIFFERENTLY PRETREATED RATS	50	4
271	11	708 1979 BIOCHEMICAL PHARMACOLOGY 28(2):231-238 DICKINS M; ELCOMBE CR; MOLONEY SJ; NETTER KJ; BRIDGES JW FURTHER-STUDIES ON THE DISSOCIATION OF THE ISOSAFROLE METABOLITE-CYTOCHROME-P-450 COMPLEX	50	6
272	5	721 1979 CHEMICO-BIOLOGICAL INTERACTIONS 28(1):17-33 APPEL KE; RUF HH; MAHR B; SCHWARZ M; RICKART R; KUNZ W BINDING OF NITROSAMINES TO CYTOCHROME-P-450 OF LIVER-MICROSOMES	50	2
273	9	733 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(17):8377-8385 KIDO T; ARAKAWA M; KIMURA T ADRENAL-CORTEX MITOCHONDRIAL CYTOCHROME-P-450 SPECIFIC TO CHOLESTEROL SIDE-CHAIN CLEAVAGE REACTION - SPECTRAL CHANGES INDUCED BY DETERGENTS, ALCOHOLS, AMINES, PHOSPHOLIPIDS, STEROID HYDROXYLASE INHIBITORS, AND STEROID SUBSTRATES, AND CONDITIONS FOR ADRENODOXIN BINDING TO THE CYTOCHROME	50	0
274	12	891 1982 BIOCHEMISTRY 21(6):1324-1330 BACKES WL; SLIGAR SG; SCHENKMAN JB KINETICS OF HEPATIC CYTOCHROME-P-450 REDUCTION - CORRELATION WITH SPIN STATE OF THE FERRIC HEME	50	11
275	2	1198 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(33):17672-17677 JOHNSON EF; SCHWAB GE; VICKERY LE POSITIVE EFFECTORS OF THE BINDING OF AN ACTIVE SITE-DIRECTED AMINO STEROID TO RABBIT CYTOCHROME-P-450-3C	50	5
276	1	18 1968 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 349(11):1624-& SCHENKMAN JB EFFECT OF SUBSTRATES ON HEPATIC MICROSOMAL CYTOCHROME P-450	49	24
277	2	127 1971 ANESTHESIOLOGY 35(3):241-& BROWN BR DIPHASIC ACTION OF HALOTHANE ON OXIDATIVE METABOLISM OF DRUGS BY LIVER - IN-VITRO STUDY IN RAT	49	8
278	5	131 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 144(1):143-& IMAI Y; SIEKEVIT.P COMPARISON OF SOME PROPERTIES OF MICROSOMAL CYTOCHROME P-450 FROM NORMAL, METHYLCHOLANTHRENE-TREATED, AND PHENOBARBITAL- TREATED RATS	49	17
279	1	579 1977 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 184(1):276-281 BARTOLI GM; GALEOTTI T; PALOMBINI G; PARISI G; AZZI A DIFFERENT CONTRIBUTION OF RAT-LIVER MICROSOMAL PIGMENTS IN FORMATION OF SUPEROXIDE ANIONS AND HYDROGEN-PEROXIDE DURING DEVELOPMENT	49	1
280	2	628 1977 LIFE SCIENCES 20(6):991-997 MEHENDALE HM; TAKANAKA A; DESAIAH D; HO IK KEPONE INDUCTION OF HEPATIC MIXED-FUNCTION OXIDASES IN MALE RAT	49	3
281	1	156 1971 BIOCHEMISTRY 10(15):2884-& HERSH LB RAT LIVER OMEGA-AMIDASE - PURIFICATION AND PROPERTIES	48	0
282	4	398 1974 MOLECULAR PHARMACOLOGY 10(5):776-789 GURTOO HL; CAMPBELL TC METABOLISM OF AFLATOXIN-B1 AND ITS METABOLISM-DEPENDENT AND INDEPENDENT BINDING TO RAT HEPATIC MICROSOMES	48	3
283	9	483 1975 MOLECULAR AND CELLULAR BIOCHEMISTRY 8(2):69-79 ELLIN A; ORRENIUS S FATTY-ACID HYDROXYLATION IN RAT-KIDNEY CORTEX MICROSOMES	48	1
284	10	980 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258(22):3444-3452 TAMBURINI PP; GIBSON GG THERMODYNAMIC STUDIES OF THE PROTEIN-PROTEIN INTERACTIONS BETWEEN CYTOCHROME-P-450 AND CYTOCHROME-B5 - EVIDENCE FOR A CENTRAL ROLE OF THE CYTOCHROME-P-450 SPIN STATE IN THE COUPLING OF SUBSTRATE AND CYTOCHROME-B5 BINDING TO THE TERMINAL HEMOPROTEI	48	0
285	2	1112 1986 CANCER RESEARCH 46(3):1224-1232 OCHS H; DUSTERBERG B; GUNZEL P; SCHULTEHERMANN R EFFECT OF TUMOR PROMOTING CONTRACEPTIVE STEROIDS ON GROWTH AND DRUG-METABOLIZING-ENZYMES IN RAT-LIVER	48	1
286	5	1193 1988 EUROPEAN JOURNAL OF BIOCHEMISTRY 172(2):315-324 SUMIMOTO H; TAKESHIGE K; MINAKAMI S CHARACTERIZATION OF HUMAN NEUTROPHIL LEUKOTRIENE-B4 OMEGA- HYDROXYLASE AS A SYSTEM INVOLVING A UNIQUE CYTOCHROME-P-450 AND NADPH CYTOCHROME-P-450 REDUCTASE	48	1
287	1	1 1967 BIOCHIMICA ET BIOPHYSICA ACTA 147(3):518-& ICHIKAWA Y; YAMANO T ROLE OF HYDROPHOBIC BONDING IN P-450 AND EFFECT OF ORGANIC COMPOUNDS ON CONVERSION OF P-450 TO P-420	47	10
288	2	22 1968 MOLECULAR PHARMACOLOGY 4(6):613-& SCHENKMAN JB; SATO R RELATIONSHIP BETWEEN PH-INDUCED SPECTRAL CHANGE IN FERRIPROTOHEME AND SUBSTRATE-INDUCED SPECTRAL CHANGE OF HEPATIC MICROSOMAL MIXED-FUNCTION OXIDASE	47	38
289	3	112 1970 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 173(2):233-& PETERS MA; FOUTS JR A STUDY OF SOME POSSIBLE MECHANISMS BY WHICH MAGNESIUM ACTIVATES HEPATIC MICROSOMAL DRUG METABOLISM IN-VITRO	47	14
290	1	300 1973 BIOCHEMISTRY 12(7):1445-1451 CAPDEVIL.J; MORELLO A; PERRY AS; AGOSIN M EFFECT OF PHENOBARBITAL AND NAPHTHALENE ON SOME OF COMPONENTS OF ELECTRON-TRANSPORT SYSTEM AND HYDROXYLATING ACTIVITY OF HOUSE-FLY MICROSOMES	47	0
291	2	625 1977 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 203(2):409-416 KARASHIMA D; HIROKATA Y; SHIGEMATSU A; FURUKAWA T INVITRO METABOLISM OF HALOTHANE (2-BROMO-2-CHLORO-1,1,1- TRIFLUOROETHANE) BY HEPATIC MICROSOMAL CYTOCHROME-P-450	47	1
292	1	645 1978 BIOCHEMICAL PHARMACOLOGY 27(3):355-358 AUCLAIR C; DEPROST D; HAKIM J SUPEROXIDE ANION PRODUCTION BY LIVER-MICROSOMES FROM PHENOBARBITAL TREATED RAT	47	1
293	10	647 1978 BIOCHEMICAL PHARMACOLOGY 27(5):783-788 ALGAILANY KAS; HOUSTON JB; BRIDGES JW ROLE OF SUBSTRATE LIPOPHILICITY IN DETERMINING TYPE-1 MICROSOMAL P450 BINDING CHARACTERISTICS	47	14
294	9	805 1980 JOURNAL OF BIOCHEMISTRY 88(2):505-516 HASHIMOTOYUTSUDO C; IMAI Y; SATO R MULTIPLE FORMS OF CYTOCHROME-P-450 PURIFIED FROM LIVER- MICROSOMES OF PHENOBARBITAL-PRETREATED AND 3- METHYLCHOLANTHRENE-PRETREATED RABBITS .2. SPECTRAL PROPERTIES	47	0
295	17	904 1982 CRC CRITICAL REVIEWS IN BIOCHEMISTRY 12(1):39-101 HLAVICA P BIOLOGICAL OXIDATION OF NITROGEN IN ORGANIC-COMPOUNDS AND DISPOSITION OF N-OXIDIZED PRODUCTS	47	2
296	1	69 1969 SCIENCE 163(3873):1297-& SIH CJ ENZYMATIC MECHANISM OF STEROID HYDROXYLATION	46	4
297	5	84 1970 BIOCHEMICAL PHARMACOLOGY 19(7):2396-& SCHENKMAN JB; CINTI DL RATE-LIMITING STEP IN AMINOPYRINE DEMETHYLASE OF RAT LIVER MICROSOMES	46	19
298	8	143 1971 BIOCHEMICAL PHARMACOLOGY 20(2):447-& KATO R; TAKANAKA A; ONODA K EFFECT OF ADRENALECTOMY OR ALLOXAN DIABETES ON SUBSTRATE INTERACTION WITH CYTOCHROME-P-450 IN OXIDATION OF DRUGS BY LIVER MICROSOMES	46	16
299	7	294 1973 BIOCHEMICAL PHARMACOLOGY 22(10):1125-1132 MGBODILE MU; HAYES JR; CAMPBELL TC EFFECT OF PROTEIN-DEFICIENCY ON INDUCIBILITY OF HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM .2. EFFECT ON ENZYME-KINETICS AND ELECTRON-TRANSPORT SYSTEM	46	0
300	9	629 1977 LIFE SCIENCES 20(6):1017-1026 GREINER JW; KRAMER RE; RUMBAUGH RC; COLBY HD DIFFERENTIAL CONTROL OF ADRENAL DRUG AND STEROID METABOLISM IN GUINEA-PIG	46	6

#	Cited nodes	Nodes / Authors	GCS	LCS
301	13	673 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253(4):1048-1058 KUMAKI K; SATO M; KON H; NEBERT DW CORRELATION OF TYPE-I, TYPE-II, AND REVERSE TYPE-I DIFFERENCE SPECTRA WITH ABSOLUTE CHANGES IN SPIN STATE OF HEPATIC MICROSOMAL CYTOCHROME-P-450 IRON FROM 5 MAMMALIAN-SPECIES	46	21
302	1	847 1981 DRUG METABOLISM AND DISPOSITION 9(6):561-564 TYBRING G; VONBAHR C; BERTILSSON L; COLLSTE H; GLAUMANN H; SOLBRAND M METABOLISM OF CARBAMAZEPINE AND ITS EPOXIDE METABOLITE IN HUMAN AND RAT-LIVER INVITRO	46	1
303	2	1371 1995 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 53(1-6):103-110 PAPADOPOULOS V; BROWN AS ROLE OF THE PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR AND THE POLYPEPTIDE DIAZEPAM-BINDING INHIBITOR IN STEROIDOGENESIS	46	0
304	4	1376 1996 BIOCHEMISTRY 35(18):5883-5892 Sennequier N; Stuehr DJ Analysis of substrate-induced electronic, catalytic, and structural changes in inducible NO synthase	46	1
305	6	207 1972 BIOCHEMICAL PHARMACOLOGY 21(11):1585-& BECKING GC INFLUENCE OF DIETARY IRON LEVELS ON HEPATIC DRUG-METABOLISM IN- VIVO AND IN-VITRO IN RAT	45	2
306	3	856 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256(13):6721-6728 HINTZ MJ; PETERSON JA THE KINETICS OF REDUCTION OF CYTOCHROME-P-450CAM BY REDUCED PUTIDAREDOXIN	45	0
307	2	1178 1988 BIOCHEMICAL PHARMACOLOGY 37(10):1971-1979 BEYELER S; TESTA B; PERRISSOUD D FLAVONOIDS AS INHIBITORS OF RAT-LIVER MONOOXYGENASE ACTIVITIES	45	0
308	4	1291 1991 LIPIDS 26(8):584-597 MERCER EI STEROL BIOSYNTHESIS INHIBITORS - THEIR CURRENT STATUS AND MODES OF ACTION	45	0
309	2	1297 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(20):9141-9145 LARSON JR; COON MJ; PORTER TD PURIFICATION AND PROPERTIES OF A SHORTENED FORM OF CYTOCHROME- P-450 2E1 - DELETION OF THE NH2-TERMINAL MEMBRANE-INSERTION SIGNAL PEPTIDE DOES NOT ALTER THE CATALYTIC ACTIVITIES	45	0
310	6	1339 1993 PROGRESS IN LIPID RESEARCH 32(4):357-416 MERCER EI INHIBITORS OF STEROL BIOSYNTHESIS AND THEIR APPLICATIONS	45	0
311	10	280 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):156-174 LU AYH; LEVIN W; WEST S; JACOBSON M; RYAN D; KUNTZMAN R; CONNEY AH ROLE OF CYTOCHROME-P-450 AND P-448 IN DRUG AND STEROID HYDROXYLATIONS	44	9
312	5	432 1975 BIOCHEMICAL PHARMACOLOGY 24(17):1644-1646 COLBY HD; KRAMER RE; GREINER JW; ROBINSON DA; KRAUSE RF; CANADY WJ HEPATIC DRUG-METABOLISM IN RETINOL-DEFICIENT RATS	44	1
313	5	178 1971 MOLECULAR PHARMACOLOGY 7(1):26-& LEIBMAN KC EFFECTS OF EXTRACTION WITH ISOOCTANE UPON PROPERTIES OF LIVER MICROSOMES	43	16
314	3	193 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 150(2):725-& PEISACH J; BLUMBERG WE; APPLEBY CA ELECTRON-PARAMAGNETIC RESONANCE AND TEMPERATURE DEPENDENT SPIN STATE STUDIES OF FERRIC CYTOCHROME-P-450 FROM RHIZOBIUM- JAPONICUM	43	8
315	5	259 1972 MOLECULAR PHARMACOLOGY 8(3):327-& CINTI DL; SCHENKMAN JB HEPATIC ORGANELLE INTERACTION .1. SPECTRAL INVESTIGATION DURING DRUG BIOTRANSFORMATION	43	9
316	2	261 1972 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 272(3):277-& BREYER U PERAZINE, CHLORPROMAZINE AND IMIPRAMINE AS INDUCERS OF MICROSOMAL DRUG-METABOLISM	43	2
317	5	283 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 155(2):355-360 WATERMAN MR; ULLRICH V; ESTABROO.RW EFFECT OF SUBSTRATE ON SPIN STATE OF CYTOCHROME-P-450 IN HEPATIC MICROSOMES	43	16
318	3	295 1973 BIOCHEMICAL PHARMACOLOGY 22(12):1463-1476 MOFFITT AE; MURPHY SD EFFECT OF EXCESS AND DEFICIENT COPPER INTAKE ON RAT-LIVER MICROSOMAL ENZYME-ACTIVITY	43	2
319	6	333 1973 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 185(2):226-234 JAKOBSSO.SV; CINTI DL STUDIES ON CYTOCHROME P-450-CONTAINING MONO-OXYGENASE SYSTEM IN HUMAN KIDNEY-CORTEX MICROSOMES	43	0
320	5	481 1975 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 6(3-4):419-425 ESTABROOK RW; MARTINEZZEDILLO G; YOUNG S; PETERSON JA; MCCARTHY J INTERACTION OF STEROIDS WITH LIVER MICROSOMAL CYTOCHROME-P-450 - GENERAL HYPOTHESIS	43	7
321	1	493 1975 TOXICOLOGY AND APPLIED PHARMACOLOGY 33(1):94-105 ECOBICHON DJ; COMEAU AM ISOMERICALLY PURE CHLOROBIPHENYL CONGENERS AND HEPATIC FUNCTION IN RAT - INFLUENCE OF POSITION AND DEGREE OF CHLORINATION	43	2
322	1	754 1979 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 76(7):3499-3503 BLOMSTRAND R; OSTLINGWINTZELL H; LOF A; MCMARTIN K; TOLF BR; HEDSTROM KG PYRAZOLES AS INHIBITORS OF ALCOHOL OXIDATION AND AS IMPORTANT TOOLS IN ALCOHOL RESEARCH - APPROACH TO THERAPY AGAINST METHANOL POISONING	43	0
323	8	877 1982 BIOCHEMICAL JOURNAL 207(1):51-56 PHILLIPSON CE; IOANNIDES C; DELAFORGE M; PARKE DV STUDIES ON THE SUBSTRATE-BINDING SITES OF LIVER MICROSOMAL CYTOCHROME P-448	43	12
324	4	1134 1986 TOXICOLOGY AND APPLIED PHARMACOLOGY 82(2):272-280 PATHIRATNE A; PUYEAR RL; BRAMMER JD A COMPARATIVE-STUDY OF THE EFFECTS OF BENZENE, TOLUENE, AND XYLENES ON THEIR INVITRO METABOLISM AND DRUG-METABOLIZING- ENZYMES IN RAT-LIVER	43	0
325	1	23 1968 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 259(2):98-& REMMER H; ESTABROO.RW; SCHENKMA.J; GREIM H REACTION OF DRUGS WITH MICROSOMAL LIVER HYDROXYLASE - ITS INFLUENCE ON DRUG ACTION	42	33
326	1	32 1969 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 134(2):308-& WITTKOP JA; PROUGH RA; REED DJ OXIDATIVE DEMETHYLATION OF N-METHYLHYDRAZINES BY RAT LIVER MICROSOMES	42	2
327	5	150 1971 BIOCHEMICAL PHARMACOLOGY 20(8):1991-& FELLER DR; GERALD MC INTERACTIONS OF SPRIONOLACTONE WITH HEPATIC MICROSOMAL DRUG- METABOLIZING ENZYME SYSTEMS	42	0
328	4	164 1971 EXPERIMENTAL AND MOLECULAR PATHOLOGY 14(2):263-& DENK H; SCHENKMAN JB; BACCHIN PG; HUTTERER F; SCHAFFNE.F; POPPER H MECHANISM OF CHOLESTASIS .3. INTERACTION OF SYNTHETIC DETERGENTS WITH MICROSOMAL CYTOCHROME-P-450 DEPENDENT BIOTRANSFORMATION SYSTEM IN-VITRO - COMPARISON BETWEEN EFFECTS OF DETERGENTS, EFFECTS OF BILE ACIDS, AND FINDINGS IN BILE DUCT LIGATED RATS	42	13
329	7	286 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 158(2):544-555 GRUNDIN R; JAKOBSSO.S; CINTI DL INDUCTION OF MICROSOMAL ARYL HYDROCARBON (3,4- BENZO(ALPHA)PYRENE) HYDROXYLASE AND CYTOCHROME P-450K IN RAT- KIDNEY CORTEX .1. CHARACTERISTICS OF HYDROXYLASE SYSTEM	42	4
330	1	376 1974 COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE D 278(11):1487-1490 BENVENIS.I; DURST F PRESENTATION OF ENZYME WITH CYTOCHROME-P-450, TRANS CINNAMIC ACID 4-HYDROXYLASE (CAH) IN TISSUES OF ARTICHOKE TUBER (HELIANTHUS-TUBEROSUS L, VARIETY COMMON WHITE)	42	0
331	4	423 1975 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 170(1):160-168 PROUGH RA; BURKE MD ROLE OF NADPH-CYTOCHROME-C REDUCTASE IN MICROSOMAL HYDROXYLATION REACTIONS	42	6
332	9	524 1976 BIOCHIMICA ET BIOPHYSICA ACTA 421(1):44-56 TSYRLOV IB; ZAKHAROVA NE; GROMOVA OA; LYAKHOVICH VV POSSIBLE MECHANISM OF INDUCTION OF LIVER MICROSOMAL MONOOXYGENASES BY PHENOBARBITAL	42	10
333	4	770 1980 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 199(2):591-605 BLOMSTRAND R; ELLIN A; LOF A; OSTLINGWINTZELL H BIOLOGICAL EFFECTS AND METABOLIC INTERACTIONS AFTER CHRONIC AND ACUTE ADMINISTRATION OF 4-METHYLPYRAZOLE AND ETHANOL TO RATS .1.	42	0
334	4	1185 1988 CANCER RESEARCH 48(9):2462-2468 SCHULTEHERMANN R; OCHS H; BURSCH W; PARZEFALL W QUANTITATIVE STRUCTURE-ACTIVITY STUDIES ON EFFECTS OF 16 DIFFERENT STEROIDS ON GROWTH AND MONOOXYGENASES OF RAT-LIVER	42	0
335	2	1342 1994 AQUATIC TOXICOLOGY 28(1-2):107-126 FENT K; BUCHELI TD INHIBITION OF HEPATIC-MICROSOMAL MONOOXYGENASE SYSTEM BY ORGANOTINS IN-VITRO IN FRESH-WATER FISH	42	1
336	1	4 1968 ANESTHESIOLOGY 29(2):327-& GREENE NM METABOLISM OF DRUGS EMPLOYED IN ANESTHESIA .2.	41	0
337	5	107 1970 JOURNAL OF BIOCHEMISTRY 68(5):613-& KATO R; TAKANAKA A; TAKAHASH.A EFFECT OF THYROID HORMONE ON SUBSTRATE INTERACTION WITH P-450 IN OXIDATION OF DRUGS BY LIVER MICROSOMES	41	4
338	8	172 1971 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 179(1):91-& FOUTS JR; POHL RJ FURTHER STUDIES ON EFFECTS OF METAL IONS ON RAT LIVER MICROSOMAL REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE- CYTOCHROME P-450 REDUCTASE	41	6
339	2	264 1972 PEDIATRIC CLINICS OF NORTH AMERICA 19(1):37-& RANE A; SJOQVIST F DRUG-METABOLISM IN HUMAN FETUS AND NEWBORN INFANT	41	3
340	5	347 1973 TOXICOLOGY AND APPLIED PHARMACOLOGY 25(4):534-541 DIAZGOME.MI; CASTRO JA; DEFERREY.EC; DACOSTA N; DECASTRO CR IRREVERSIBLE BINDING OF C-14 FROM C-14/CL4 TO LIVER MICROSOMAL LIPIDS AND PROTEINS FROM RATS PRETREATED WITH COMPOUNDS ALTERING MICROSOMAL MIXED-FUNCTION OXYGENASE ACTIVITY	41	0
341	5	494 1975 TOXICOLOGY AND APPLIED PHARMACOLOGY 34(1):102-114 DIAZGOMEZ MI; CASTRO CRD; DACOSTA N; FENOS OMD; FERREYRA ECD; CASTRO JA SPECIES-DIFFERENCES IN CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY - ROLE OF CCL4 ACTIVATION AND OF LIPID PEROXIDATION	41	4
342	4	598 1977 BIOCHEMISTRY 16(4):593-600 UZGIRIS VI; GRAVES PE; SALHANICK HA LIGAND MODIFICATION OF CORPUS-LUTEUM MITOCHONDRIAL CYTOCHROME- P-450 SPECTRA AND CHOLESTEROL MONO-OXYGENATION - ASSAY OF ENZYME-SPECIFIC INHIBITORS	41	3
343	4	652 1978 BIOCHEMICAL PHARMACOLOGY 27(19):2301-2304 ULLRICH V; HERMANN G; WEBER P NITRITE FORMATION FROM 2-NITROPROPANE BY MICROSOMAL MONO- OXYGENASES	41	0
344	2	715 1979 BIOCHEMICAL PHARMACOLOGY 28(13):1993-2000 KAMATAKI T; SUGIURA M; YAMAZOE Y; KATO R PURIFICATION AND PROPERTIES OF CYTOCHROME-P-450 AND NADPH- CYTOCHROME-C (P-450) REDUCTASE FROM HUMAN-LIVER MICROSOMES	41	2
345	2	1018 1984 EUROPEAN JOURNAL OF BIOCHEMISTRY 140(3):583-591 HUME R; KELLY RW; TAYLOR PL; BOYD GS THE CATALYTIC CYCLE OF CYTOCHROME-P-450SCC AND INTERMEDIATES IN THE CONVERSION OF CHOLESTEROL TO PREGNENOLONE	41	0
346	7	1089 1985 VITAMINS AND HORMONES-ADVANCES IN RESEARCH AND APPLICATIONS 42():315-368 HALL PF ROLE OF CYTOCHROMES-P-450 IN THE BIOSYNTHESIS OF STEROID- HORMONES	41	2
347	1	1177 1988 BIOCHEMICAL PHARMACOLOGY 37(10):1947-1953 FABRE G; CREVATPISANO P; DRAGNA S; COVO J; BARRA Y; CANO JP INVOLVEMENT OF THE MACROLIDE ANTIBIOTIC INDUCIBLE CYTOCHROME-P- 450 LM3C IN THE METABOLISM OF MIDAZOLAM BY MICROSOMAL FRACTIONS PREPARED FROM RABBIT LIVER	41	1
348	2	83 1970 BIOCHEMICAL PHARMACOLOGY 19(6):1955-& ACKERMAN.E DEMETHYLATION OF AMINOPHENAZONE AND CODEINE IN HUMAN LIVERS - STUDY ON MICROSOMAL ELECTRON TRANSPORT	40	0
349	4	188 1971 ZEITSCHRIFT FUR NATURFORSCHUNG PART B-CHEMIE BIOCHEMIE BIOPHYSIK BIOLOGIE UND VERWANDTEN GEBIETE B 26(4):322-& FROMMER U; ULLRICH V HYDROXYLATION OF ALIPHATIC COMPOUNDS BY LIVER MICROSOMES .3. MODEL HYDROXYLATION REACTIONS	40	0
350	4	250 1972 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 182(2):320-& SOYKA LF; LONG RJ IN-VITRO INHIBITION OF DRUG-METABOLISM BY METABOLITES OF PROGESTERONE	40	3
351	7	519 1976 BIOCHEMICAL PHARMACOLOGY 25(19):2187-2195 BURKE MD; PROUGH RA SOME CHARACTERISTICS OF HAMSTER LIVER AND LUNG MICROSOMAL ARYL- HYDROCARBON (BIPHENYL AND BENZO(A)PYRENE) HYDROXYLATION REACTIONS	40	3
352	1	561 1976 SCIENCE 194(4261):195-197 AGOSIN M; NAQUIRA C; PAULIN J; CAPDEVILA J CYTOCHROME-P-450 AND DRUG-METABOLISM IN TRYPANOSOMA-CRUZI - EFFECTS OF PHENOBARBITAL	40	1
353	11	812 1980 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 214(1):80-86 HINES RN; PROUGH RA THE CHARACTERIZATION OF A INHIBITORY COMPLEX FORMED WITH CYTOCHROME-P-450 AND A METABOLITE OF 1,1-DISUBSTITUTED HYDRAZINES	40	3
354	8	1008 1984 BIOCHEMISTRY 23(20):4526-4533 TAMBURINI PP; GIBSON GG; BACKES WL; SLIGAR SG; SCHENKMAN JB REDUCTION KINETICS OF PURIFIED RAT-LIVER CYTOCHROME-P-450 - EVIDENCE FOR A SEQUENTIAL REACTION-MECHANISM DEPENDENT ON THE HEMOPROTEIN SPIN STATE	40	9
355	6	1172 1987 XENOBIOTICA 17(1):45-57 LAVRIJSEN K; VANHOUDT J; THIJS D; MEULDERMANS W; HEYKANTS J INTERACTION OF MICONAZOLE, KETOCONAZOLE AND ITRACONAZOLE WITH RAT-LIVER MICROSOMES	40	3
356	3	1186 1988 COORDINATION CHEMISTRY REVIEWS 86():245-271 BACCI M STATIC AND DYNAMIC EFFECTS IN SPIN EQUILIBRIUM SYSTEMS	40	0
357	4	100 1970 INTERNATIONAL JOURNAL OF CANCER 6(3):470-& NEBERT DW; BAUSSERM.LL; BATES RR EFFECT OF 17-BETA-ESTRADIOL AND TESTOSTERONE ON ARYL HYDROCARBON HYDROXYLASE ACTIVITY IN MOUSE TISSUES IN-VIVO AND IN CELL CULTURE	39	1
358	6	181 1971 MOLECULAR PHARMACOLOGY 7(6):683-& GLAZER RI; SCHENKMAN JB; SARTOREL.AC IMMUNOCHEMICAL STUDIES ON ROLE OF REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE-CYTOCHROME-C (P-450) REDUCTASE IN DRUG OXIDATION	39	7
359	6	274 1972 XENOBIOTICA 2(3):259-& VAINIO H; HANNINEN O ENHANCEMENT OF ANILINE PARA HYDROXYLATION BY ACETONE IN RAT- LIVER MICROSOMES	39	9
360	4	449 1975 CHEMICAL & PHARMACEUTICAL BULLETIN 23(4):824-830 ARIYOSHI T; IDEGUCHI K; IWASAKI K; ARAKAKI M RELATIONSHIP BETWEEN CHEMICAL-STRUCTURE AND ACTIVITY .2. INFLUENCES OF ISOMERS IN DICHLOROBENZENE, TRICHLOROBENZENE, AND TETRACHLOROBENZENE ON ACTIVITIES OF DRUG-METABOLIZING-ENZYMES	39	4
361	4	517 1976 BIOCHEMICAL PHARMACOLOGY 25(13):1495-1500 HAYES JS; BRENDEL K N-DEMETHYLATION AS AN EXAMPLE OF DRUG-METABOLISM IN ISOLATED RAT HEPATOCYTES	39	1
362	25	687 1978 PHARMACOLOGY & THERAPEUTICS PART A-CHEMOTHERAPY TOXICOLOGY AND METABOLIC INHIBITORS 2(4):727-749 CINTI DL AGENTS ACTIVATING LIVER MICROSOMAL MIXED-FUNCTION OXIDASE SYSTEM	39	4
363	1	765 1979 XENOBIOTICA 9(12):737-743 EMEROLE GO; NESKOVIC N; DIXON RL DETOXICATION OF AFLATOXIN-B1 WITH GLUTATHIONE IN THE RAT	39	0
364	4	796 1980 DRUG METABOLISM REVIEWS 11(2):191-221 BAARS AJ BIOTRANSFORMATION OF XENOBIOTICS IN DROSOPHILA-MELANOGASTER AND ITS RELEVANCE FOR MUTAGENICITY TESTING	39	0
365	13	882 1982 BIOCHEMICAL PHARMACOLOGY 31(7):1315-1320 DICKINS M; BRIDGES JW THE RELATIONSHIP BETWEEN THE BINDING OF 2-NORMAL- ALKYLBENZIMIDAZOLES TO RAT HEPATIC-MICROSOMAL CYTOCHROME-P-450 AND THE INHIBITION OF MONOOXYGENATION	39	4
366	4	49 1969 EUROPEAN JOURNAL OF BIOCHEMISTRY 9(3):415-& ORRENIUS S; THOR H FATTY ACID INTERACTION WITH HYDROXYLATING ENZYME SYSTEM OF RAT LIVER MICROSOMES	38	15
367	3	248 1972 JOURNAL OF LABORATORY AND CLINICAL MEDICINE 79(3):439-& ALVARES AP; KAPPAS A INFLUENCE OF PHENOBARBITAL ON METABOLISM AND ANALGESIC EFFECT OF METHADONE IN RATS	38	0
368	9	330 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(20):7263-7271 CHENG SC; HARDING BW SUBSTRATE-INDUCED DIFFERENCE SPECTRAL, ELECTRON-PARAMAGNETIC RESONANCE, AND ENZYMATIC PROPERTIES OF CHOLESTEROL-DEPLETED MITOCHONDRIAL CYTOCHROME-P-450 OF BOVINE ADRENAL-CORTEX	38	4
369	8	363 1974 BIOCHEMICAL PHARMACOLOGY 23(10):1467-1477 PATEL JM; PAWAR SS RIBOFLAVIN AND DRUG-METABOLISM IN ADULT MALE AND FEMALE RATS	38	4
370	15	364 1974 BIOCHEMICAL PHARMACOLOGY 23(12):1721-1731 HAYES JR; CAMPBELL TC EFFECT OF PROTEIN-DEFICIENCY ON INDUCIBILITY OF HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM .3. EFFECT OF 3- METHYLCHOLANTHRENE INDUCTION ON ACTIVITY AND BINDING KINETICS	38	4
371	6	390 1974 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 22(3):360-366 HODGSON E; TATE LG; KULKARNI AP; PLAPP FW MICROSOMAL CYTOCHROME-P-450 - CHARACTERIZATION AND POSSIBLE ROLE IN INSECTICIDE RESISTANCE IN MUSCA-DOMESTICA	38	4
372	10	497 1975 XENOBIOTICA 5(6):357-376 BURKE MD; BRIDGES JW BIPHENYL HYDROXYLATIONS AND SPECTRALLY APPARENT INTERACTIONS WITH LIVER-MICROSOMES FROM HAMSTERS PRETREATED WITH PHENOBARBITONE AND 3-METHYLCHOLANTHRENE	38	5
373	3	528 1976 CANCER TREATMENT REPORTS 60(9):1285-1294 GURTOO HL; GESSNER T; CULLITON P STUDIES OF EFFECTS OF CYCLOPHOSPHAMIDE, VINCRISTINE, AND PREDNISONE ON SOME HEPATIC OXIDATIONS AND CONJUGATIONS	38	0
374	3	1147 1987 BIOCHEMICAL PHARMACOLOGY 36(18):2921-2926 RAUCY J; FERNANDES P; BLACK M; YANG SL; KOOP DR IDENTIFICATION OF A HUMAN-LIVER CYTOCHROME-P-450 EXHIBITING CATALYTIC AND IMMUNOCHEMICAL SIMILARITIES TO CYTOCHROME-P-450- 3A OF RABBIT LIVER	38	1
375	2	38 1969 BIOCHEMICAL PHARMACOLOGY 18(6):1501-& HLAVICA P; KIESE M N-OXYGENATION OF N-ALKYL- AND N,N-DIALKYLANILINES BY RABBIT LIVER MICROSOMES	37	3
376	2	46 1969 BIOCHIMICA ET BIOPHYSICA ACTA 180(1):18-& STRITTMA.CF; UMBERGER FT OXIDATIVE ENZYME COMPONENTS OF AVIAN LIVER MICROSOMES - CHANGES DURING EMBRYONIC DEVELOPMENT AND EFFECTS OF PHENOBARBITAL ADMINISTRATION	37	0
377	1	202 1972 BIOCHEMICAL JOURNAL 128(5):1285-& SHAW YS; CHEN C RING HYDROXYLATION OF DI-TERTA-BUTYLHYDROXYTOLUENE BY RAT-LIVER MICROSOMAL PREPARATIONS	37	1
378	6	632 1977 MOLECULAR PHARMACOLOGY 13(6):1092-1104 IBA MM; SOYKA LF; SCHULMAN MP CHARACTERISTICS OF LIVER MICROSOMAL DRUG-METABOLIZING ENZYME- SYSTEM OF NEWBORN RATS	37	3
379	1	880 1982 BIOCHEMICAL PHARMACOLOGY 31(7):1273-1277 BOCK KW; LILIENBLUM W; PFEIL H FUNCTIONAL-HETEROGENEITY OF UDP-GLUCURONOSYLTRANSFERASE ACTIVITIES IN C57BL/6 AND DBA/2 MICE	37	0
380	6	927 1982 MEDICAL BIOLOGY 60(5):237-254 SUOLINNA EM ISOLATION AND CULTURE OF LIVER-CELLS AND THEIR USE IN THE BIOCHEMICAL-RESEARCH OF XENOBIOTICS	37	0
381	4	1082 1985 PHOTOCHEMISTRY AND PHOTOBIOLOGY 42(6):779-783 KJELLBOM P; LARSSON C; ASKERLUND P; SCHELIN C; WIDELL S CYTOCHROME-P-450-420 IN PLANT PLASMA-MEMBRANES - A POSSIBLE COMPONENT OF THE BLUE-LIGHT-REDUCIBLE FLAVOPROTEIN-CYTOCHROME COMPLEX	37	0
382	4	1430 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(15):8882-8889 Babu BR; Griffith OW N-5-(1-imino-5-butenyl)-L-ornithine - A neuronal isoform selective mechanism-based inactivator of nitric oxide synthase	37	0
383	2	40 1969 BIOCHEMICAL PHARMACOLOGY 18(10):2561-& ANDERS MW STIMULATION IN VITRO OF MICROSOMAL ANILINE HYDROXYLATION BY 2,2'-BIPYRIDINE	36	12
384	4	88 1970 BIOCHIMICA ET BIOPHYSICA ACTA 208(1):116-& KATO R; TAKAHASH.A; OMORI Y EFFECTS OF THYROXINE AND THYROIDECTOMY ON HYDROXYLATION OF TESTOSTERONE BY LIVER MICROSOMES FROM MALE AND FEMALE RATS	36	4
385	2	116 1970 LIFE SCIENCE PART 1 PHYSIOLOGY & PHARMACOLOGY 9(18):1039-& MATTHEWS HB; SKRINJAR.M; CASIDA JE INSECTICIDE SYNERGIST INTERACTIONS WITH CYTOCHROME-P-450 IN MOUSE LIVER MICROSOMES	36	10
386	2	145 1971 BIOCHEMICAL PHARMACOLOGY 20(6):1061-& AUST SD; STEVENS JB AMINOPYRINE DEMETHYLASE - MULTIPLICITY SHOWN BY DIELDRIN AND DDT INHIBITION	36	8
387	1	200 1972 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 47(2):315-& CASTRO JA; CASTRO CRD; DACOSTA N; FERREYRA EC; FENOS OMD; DIAZGOME.MI CARBON-TETRACHLORIDE EFFECT ON RAT-LIVER AND ADRENALS RELATED TO THEIR MIXED-FUNCTION OXYGENASE CONTENT	36	3
388	4	279 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):27-49 ESTABROO.RW; MASON JI; BARON J; LAMBETH D; WATERMAN M DRUGS, ALCOHOL AND SEX-HORMONES - MOLECULAR PERSPECTIVE OF RECEPTIVITY OF CYTOCHROME-P-450	36	0
389	2	437 1975 BIOCHEMICAL SOCIETY TRANSACTIONS 3(2):278-281 WISEMAN A; GONDAL JA; SIMS P 4'-HYDROXYLATION OF BIPHENYL BY YEAST CONTAINING CYTOCHROME-P- 450 - RADIATION AND THERMAL-STABILITY, COMPARISONS WITH LIVER- ENZYME (OXIDIZED AND REDUCED FORMS)	36	0
390	2	448 1975 CHEMICAL & PHARMACEUTICAL BULLETIN 23(4):817-823 ARIYOSHI T; IDEGUCHI K; ISHIZUKA Y; IWASAKI K; ARAKAKI M RELATIONSHIP BETWEEN CHEMICAL-STRUCTURE AND ACTIVITY .1. EFFECTS OF NUMBER OF CHLORINE ATOMS IN CHLORINATED BENZENES ON COMPONENTS OF DRUG-METABOLIZING SYSTEM AND HEPATIC CONSTITUENTS	36	4
391	1	551 1976 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 198(3):709-715 GREINER JW; KRAMER RE; JARRELL J; COLBY HD MECHANISM OF ACTION OF SPIRONOLACTONE ON ADRENOCORTICAL FUNCTION IN GUINEA-PIGS	36	3
392	6	889 1982 BIOCHEMICAL PHARMACOLOGY 31(17):2745-2753 BAST A; NOORDHOEK J SPECTRAL INTERACTION OF ORPHENADRINE AND ITS METABOLITES WITH OXIDIZED AND REDUCED HEPATIC-MICROSOMAL CYTOCHROME-P-450 IN THE RAT	36	2
393	2	992 1983 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 80(21):6680-6684 BURKA LT; PLUCINSKI TM; MACDONALD TL MECHANISMS OF HYDROXYLATION BY CYTOCHROME-P-450 - METABOLISM OF MONOHALOBENZENES BY PHENOBARBITAL-INDUCED MICROSOMES	36	0
394	1	1408 1997 FOOD AND CHEMICAL TOXICOLOGY 35(2):225-239 Poon R; Lecavalier P; Mueller R; Valli VE; Procter BG; Chu I Subchronic oral toxicity of Di-n-octyl phthalate and di(2- ethylhexyl) phthalate in the rat	36	0
395	7	105 1970 JOURNAL OF BIOCHEMISTRY 68(3):395-& KATO R; TAKANAKA A; TAKAYANA.M SUBSTRATE-INDUCED SPECTRAL CHANGE OF LIVER MICROSOMES IN PHENOBARBITAL AND METHYLCHOLANTHRENE-TREATED MALE AND FEMALE RATS	35	15
396	4	206 1972 BIOCHEMICAL PHARMACOLOGY 21(7):975-& CHRISTEN.F; WISSING F INHIBITION OF MICROSOMAL DRUG-METABOLIZING ENZYMES FROM RAT- LIVER BY VARIOUS 4-HYDROXYCOUMARIN DERIVATIVES	35	0
397	3	369 1974 BIOCHEMICAL PHARMACOLOGY 23(22):3191-3197 JONSSON JA HYDROXYLATION OF AMPHETAMINE TO PARAHYDROXYAMPHETAMINE BY RAT- LIVER MICROSOMES	35	2
398	2	409 1974 XENOBIOTICA 4(4):209-217 PALMER ED; CAWTHORN.MA EFFECTS OF 1-ALKYLIMIDAZOLES ON HEPATIC DRUG-METABOLIZING ENZYME-ACTIVITY	35	13
399	8	453 1975 CHEMICO-BIOLOGICAL INTERACTIONS 10(3):215-228 MAILMAN RB; TATE LG; MUSE KE; COONS LB; HODGSON E OCCURRENCE OF MULTIPLE FORMS OF CYTOCHROME-P-450 IN HEPATIC MICROSOMES FROM UNTREATED RATS AND MICE	35	12
400	5	569 1976 XENOBIOTICA 6(11):691-711 ARFWIDSSON A; BORG KO; HOFFMANN KJ; SKANBERG I METABOLISM OF METOPROLOL IN RAT INVITRO AND INVIVO	35	0

#	Cited nodes	Nodes / Authors	GCS	LCS
401	4	596 1977 BIOCHEMICAL PHARMACOLOGY 26(22):2117-2120 YIH TD; VANROSSUM JM KS-VALUES OF SOME HOMOLOGOUS SERIES OF BARBITURATES AND RELATIONSHIP WITH LIPOPHILICITY AND METABOLIC-CLEARANCE	35	4
402	4	663 1978 ENDOCRINOLOGY 103(4):1313-1320 GREINER JW; RUMBAUGH RC; KRAMER RE; COLBY HD RELATION OF CANRENONE TO ACTIONS OF SPIRONOLACTONE ON ADRENAL CYTOCHROME P-450-DEPENDENT ENZYMES	35	0
403	1	734 1979 JOURNAL OF MEDICINAL CHEMISTRY 22(12):1509-1517 TATEE T; CARLSON KE; KATZENELLENBOGEN JA; ROBERTSON DW; KATZENELLENBOGEN BS ANTI-ESTROGENS AND ANTI-ESTROGEN METABOLITES - PREPARATION OF TRITIUM-LABELED (+/-)-CIS-3-[P-(1,2,3,4-TETRAHYDRO-6-METHOXY-2- PHENYL-1-NAPHTHYL)PHENOXY]-1,2-PROPANEDIOL (U-23469) AND CHARACTERIZATION AND SYNTHESIS OF A BIOLOGICALLY IMPORTANT METABOLITE	35	0
404	3	784 1980 CANCER 45(5):1060-1065 STROBEL HW; FANG WF; OSHINSKY RJ ROLE OF COLONIC CYTOCHROME-P-450 IN LARGE BOWEL CARCINOGENESIS	35	0
405	3	806 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(4):1339-1345 SONO M; TANIGUCHI T; WATANABE Y; HAYAISHI O INDOLEAMINE 2,3-DIOXYGENASE - EQUILIBRIUM STUDIES OF THE TRYPTOPHAN BINDING TO THE FERRIC, FERROUS, AND CO-BOUND ENZYMES	35	0
406	3	887 1982 BIOCHEMICAL PHARMACOLOGY 31(11):2083-2092 COSTA AK; IVANETICH KM VINYLIDENE-CHLORIDE - ITS METABOLISM BY HEPATIC-MICROSOMAL CYTOCHROME-P-450 INVITRO	35	0
407	5	915 1982 JOURNAL OF BIOCHEMISTRY 91(5):1651-1659 YOSHIDA Y; IMAI Y; HASHIMOTOYUTSUDO C SPECTROPHOTOMETRIC EXAMINATION OF EXOGENOUS-LIGAND COMPLEXES OF FERRIC CYTOCHROME-P-450 - CHARACTERIZATION OF THE AXIAL LIGAND TRANS TO THIOLATE IN THE NATIVE FERRIC LOW-SPIN FORM	35	1
408	2	1003 1984 BIOCHEMICAL PHARMACOLOGY 33(1):115-123 MELTZER NM; STANG P; STERNSON LA; WADE AE INFLUENCE OF TAMOXIFEN AND ITS N-DESMETHYL AND 4-HYDROXY METABOLITES ON RAT-LIVER MICROSOMAL-ENZYMES	35	2
409	2	169 1971 JOURNAL OF BIOLOGICAL CHEMISTRY 246(22):6953-& PARLI CJ; WANG N; MCMAHON RE ENZYMATIC N-HYDROXYLATION OF AN IMINE - NEW CYTOCHROME P-450- DEPENDENT REACTION CATALYZED BY HEPATIC MICROSOMAL MONOOXYGENASES	34	1
410	4	339 1973 MOLECULAR PHARMACOLOGY 9(6):840-845 JANSSON I; SCHENKMAN JB EVIDENCE AGAINST PARTICIPATION OF CYTOCHROME B5 IN HEPATIC MICROSOMAL MIXED-FUNCTION OXIDASE REACTION	34	7
411	2	869 1981 TOXICOLOGY AND APPLIED PHARMACOLOGY 60(2):229-240 LAKE BG; HARRIS RA; PHILLIPS JC; GANGOLLI SD STUDIES ON THE EFFECTS OF L-ASCORBIC-ACID ON ACETAMINOPHEN- INDUCED HEPATOTOXICITY .1. INHIBITION OF THE COVALENT BINDING OF ACETAMINOPHEN METABOLITES TO HEPATIC MICROSOMES INVITRO	34	1
412	3	929 1982 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79(19):5773-5777 SHEETS JJ; VICKERY LE PROXIMITY OF THE SUBSTRATE BINDING-SITE AND THE HEME-IRON CATALYTIC SITE IN CYTOCHROME P-450SCC	34	1
413	13	1045 1984 XENOBIOTICA 14(1-2):27-47 GIBSON GG; TAMBURINI PP CYTOCHROME-P-450 SPIN STATE - INORGANIC BIOCHEMISTRY OF HEME IRON LIGATION AND FUNCTIONAL-SIGNIFICANCE	34	11
414	2	55 1969 JOURNAL OF BIOCHEMISTRY 65(2):325-& TAKAHASH.A; KATO R EFFECT OF TOXOHORMONE ON MICROSOMAL CYTOCHROMES AND HYDROXYLATING SYSTEMS OF RAT LIVER	33	0
415	5	146 1971 BIOCHEMICAL PHARMACOLOGY 20(6):1093-& KATO RY; ONODA KI; TAKANAKA A SPECIES DIFFERENCES IN EFFECT OF MORPHINE ADMINISTRATION OR ADRENALECTOMY ON SUBSTRATE INTERACTIONS WITH CYTOCHROME P-450 AND DRUG OXIDATIONS BY LIVER MICROSOMES	33	0
416	4	171 1971 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 177(3):556-& DAVIS DC; SCHROEDE.DH; GRAM TE; REAGAN RL; GILLETTE JR COMPARISON OF EFFECTS OF HALOTHANE AND CCL4 ON HEPATIC DRUG METABOLIZING SYSTEM	33	1
417	1	658 1978 BRITISH JOURNAL OF PHARMACOLOGY 62(4):529-536 GOLDBERG A; MEREDITH PA; MILLER S; MOORE MR; THOMPSON GG HEPATIC DRUG-METABOLISM AND HEME BIOSYNTHESIS IN LEAD-POISONED RATS	33	0
418	8	726 1979 DRUG METABOLISM REVIEWS 10(2):153-185 COOPER DY; SCHLEYER H; LEVIN SS; EISENHARDT RH; NOVACK BG; ROSENTHAL O A RE-EVALUATION OF THE ROLE OF CYTOCHROME-P-450 AS THE TERMINAL OXIDASE IN HEPATIC-MICROSOMAL MIXED-FUNCTION OXIDASE CATALYZED- REACTIONS	33	4
419	2	1039 1984 TOXICOLOGY AND APPLIED PHARMACOLOGY 73(3):511-524 SMITH JH; HOOK JB MECHANISM OF CHLOROFORM NEPHROTOXICITY .3. RENAL AND HEPATIC- MICROSOMAL METABOLISM OF CHLOROFORM IN MICE	33	0
420	3	1191 1988 DRUG METABOLISM AND DISPOSITION 16(6):823-828 KYEREMATEN GA; OWENS GF; CHATTOPADHYAY B; DEBETHIZY JD; VESELL ES SEXUAL DIMORPHISM OF NICOTINE METABOLISM AND DISTRIBUTION IN THE RAT - STUDIES INVIVO AND INVITRO	33	0
421	1	57 1969 JOURNAL OF MEDICINAL CHEMISTRY 12(2):207-& MCMAHON RE; MILLS J; CULP HW; GIBSON WR; MILLER WM; MARSHALL FJ DEMETHYLATION STUDIES .6. INHIBITION OF HEPATIC MICROSOMAL OXYGENATION BY 2,4-DICHLORO(6-PHENYLPHENOXY)ETHYLAMINE AND RELATED COMPOUNDS	32	3
422	2	154 1971 BIOCHEMICAL PHARMACOLOGY 20(11):3021-& LECHNER MC; POUSADA CR POSSIBLE ROLE OF LIVER MICROSOMAL ALKALINE RIBONUCLEASE IN STIMULATION OF OXIDATIVE DRUG METABOLISM BY PHENOBARBITAL, CHLORDANE AND CHLOROPHENOTHANE (DDT)	32	0
423	6	184 1971 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 270(1):41-& BOHN W; ULLRICH V; STAUDING.H SPECIES OF CYTOCHROME P-450 IN RAT LIVER MICROSOMES WITH DIFFERENT STEREOSELECTIVITY FOR BINDING AND MONOOXYGENATION OF (+)-METHYLPHENOBARBITAL AND (-)-METHYLPHENOBARBITAL	32	10
424	3	349 1973 XENOBIOTICA 3(1):37-48 RANE A; BERGGREN M; YAFFE S; ERICSSON JL OXIDATIVE DRUG-METABOLISM IN PERINATAL RABBIT LIVER AND PLACENTA - BIOCHEMICAL AND MORPHOLOGIC STUDY	32	2
425	2	353 1974 ANESTHESIOLOGY 41(4):375-379 TAKAHASH.S; SHIGEMAT.A; FURUKAWA T INTERACTION OF VOLATILE ANESTHETICS WITH RAT HEPATIC MICROSOMAL CYTOCHROME-P-450	32	0
426	5	387 1974 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 355(11):1341-1349 MANSUY D; DUPPEL W; RUF HH; ULLRICH V PHOSPHINES AS LIGANDS TO MICROSOMAL CYTOCHROME-P-450	32	6
427	6	427 1975 BIOCHEMICAL PHARMACOLOGY 24(12):301-303 BELINA H; COOPER SD; FARKAS R; FEUER G SEX DIFFERENCE IN PHOSPHOLIPID COMPOSITION OF RAT-LIVER MICROSOMES	32	1
428	4	462 1975 EUROPEAN JOURNAL OF BIOCHEMISTRY 51(2):511-519 SCHUSTER I; FLESCHURZ C; HELM I INTERACTION OF A LIPOPHILIC DRUG WITH DIFFERENT SITES OF RAT- LIVER MICROSOMES - EQUILIBRIUM STUDIES WITH A SUBSTITUTED PLEUROMUTILIN	32	6
429	10	535 1976 DRUG METABOLISM AND DISPOSITION 4(1):17-24 TREDGER JM; CHHABRA RS; FOUTS JR POSTNATAL-DEVELOPMENT OF MIXED-FUNCTION OXIDATION AS MEASURED IN MICROSOMES FROM SMALL-INTESTINE AND LIVER OF RABBITS	32	6
430	4	611 1977 DRUG METABOLISM AND DISPOSITION 5(2):198-204 AHMED AE; KUBIC VL; ANDERS MW METABOLISM OF HALOFORMS TO CARBON-MONOXIDE .1. INVITRO STUDIES	32	1
431	1	633 1977 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 298(2):107-113 REMMER H; ALBRECHT D; KAPPUS H LIPID PEROXIDATION IN ISOLATED HEPATOCYTES FROM RATS INGESTING ETHANOL CHRONICALLY	32	1
432	3	827 1980 XENOBIOTICA 10(6):435-445 ELOVAARA E; COLLAN Y; PFAFFLI P; VAINIO H THE COMBINED TOXICITY OF TECHNICAL GRADE XYLENE AND ETHANOL IN THE RAT	32	2
433	4	1101 1986 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 246(1):19-32 WHITE RE; MCCARTHY MB ACTIVE-SITE MECHANICS OF LIVER MICROSOMAL CYTOCHROME-P-450	32	2
434	4	1116 1986 CHEMICO-BIOLOGICAL INTERACTIONS 59(2):157-171 TESTAI E; VITTOZZI L BIOCHEMICAL-ALTERATIONS ELICITED IN RAT-LIVER MICROSOMES BY OXIDATION AND REDUCTION PRODUCTS OF CHLOROFORM METABOLISM	32	3
435	2	1137 1986 VETERINARY RESEARCH COMMUNICATIONS 10(4):317-324 FARGETTON X; GALTIER P; DELATOUR P SULFOXIDATION OF ALBENDAZOLE BY A CYTOCHROME P450-INDEPENDENT MONOOXYGENASE FROM RAT-LIVER MICROSOMES	32	0
436	1	1398 1997 BIOCHEMICAL JOURNAL 328():349-352 Pfeiffer S; Gorren ACF; Pitters E; Schmidt K; Werner ER; Mayer B Allosteric modulation of rat brain nitric oxide synthase by the pterin-site enzyme inhibitor 4-aminotetrahydrobiopterin	32	0
437	6	82 1970 BIOCHEMICAL PHARMACOLOGY 19(5):1729-& GURTOO HL; CAMPBELL TC A KINETIC APPROACH TO A STUDY OF INDUCTION OF RAT LIVER MICROSOMAL HYDROXYLASE AFTER PRETREATMENT WITH 3,4-BENZPYRENE AND AFLATOXIN-B1	31	7
438	7	114 1970 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 174(2):211-& KATO R; TAKASHI A; OHSHIMA T; HOSOYA E EFFECT OF MORPHINE ADMINISTRATION ON HYDROXLYLATION OF STEROID HORMONES BY RAT LIVER MICROSOMES	31	3
439	1	151 1971 BIOCHEMICAL PHARMACOLOGY 20(8):2027-& TORRIELL.MV; SLATER TF INHIBITION OF NADPH-CYTOCHROME C REDICTASE BY PROPYL GALLATE	31	0
440	8	296 1973 BIOCHEMICAL PHARMACOLOGY 22(14):1717-1728 WILSON JT GROWTH-HORMONE MODULATION OF LIVER DRUG METABOLIC ENZYME- ACTIVITY IN RAT .1. EFFECT OF HORMONE ON CONTENT AND RATE OF REDUCTION OF MICROSOMAL CYTOCHROME-P-450	31	4
441	4	332 1973 JOURNAL OF NUTRITION 103(6):811-820 ANTHONY LE EFFECTS OF PROTEIN-CALORIE MALNUTRITION ON DRUG-METABOLISM IN RAT-LIVER MICROSOMES	31	2
442	3	356 1974 ARCHIVES OF TOXICOLOGY 32(2):69-81 SCHMOLDT A; BENTHE HF; FRUHLING R INDUCTION OF RAT-LIVER ENZYMES BY POLYCHLORINATED BIPHENYLS (PCBS) IN DEPENDENCE ON DOSE AND CHLORINE CONTENT	31	5
443	3	378 1974 DRUG METABOLISM AND DISPOSITION 2(2):194-201 SYMMS KG; JUCHAU MR ANILINE HYDROXYLASE AND NITROREDUCTASE ACTIVITIES OF PARTIALLY PURIFIED CYTOCHROMES P-450 AND P-420, AND CYTOCHROME-B5 SOLUBILIZED FROM RABBIT HEPATIC MICROSOMES	31	4
444	6	759 1979 TOXICOLOGY AND APPLIED PHARMACOLOGY 48(3):445-458 ELHAWARI AM; PLAA GL IMPAIRMENT OF HEPATIC MIXED-FUNCTION OXIDASE ACTIVITY BY ALPHA- NAPHTHYLISOTHIOCYANATE AND BETA-NAPHTHYLISOTHIOCYANATE - RELATIONSHIP TO HEPATOTOXICITY	31	1
445	6	792 1980 CHEMICO-BIOLOGICAL INTERACTIONS 32(1-2):101-110 DELAFORGE M; IOANNIDES C; PARKE DV INHIBITION OF CYTOCHROME P-448 MIXED-FUNCTION OXIDASE ACTIVITY FOLLOWING ADMINISTRATION OF 9-HYDROXYELLIPTICINE TO RATS	31	6
446	4	990 1983 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 19(1):44-52 RIVIERE JL PROCHLORAZ, A POTENT INDUCER OF THE MICROSOMAL CYTOCHROME-P-450 SYSTEM	31	2
447	1	1190 1988 DRUG METABOLISM AND DISPOSITION 16(4):557-562 SABOURIN PJ; TYNES RE; PHILPOT RM; WINQUIST S; DAHL AR DISTRIBUTION OF MICROSOMAL MONOOXYGENASES IN THE RABBIT RESPIRATORY-TRACT	31	1
448	3	1316 1992 CHEMICO-BIOLOGICAL INTERACTIONS 81(3):271-289 LAURIAULT VV; KHAN S; OBRIEN PJ HEPATOCYTE CYTOTOXICITY INDUCED BY VARIOUS HEPATOTOXINS MEDIATED BY CYTOCHROME P-450IIE1 - PROTECTION WITH DIETHYLDITHIOCARBAMATE ADMINISTRATION	31	1
449	1	5 1968 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 123(3):484-& OLDHAM SB; WILSON LD; LANDGRAF WL; HARDING BW STUDIES ON ADRENAL CORTICAL CYTOCHROME P-450 .I. EFFECTS OF SUBSTRATES AND ELECTRON DONORS ON ITS CATALYTIC SPECTRAL AND ELECTRON PARAMAGNETIC RESONANCE PROPERTIES	30	13
450	1	79 1970 BIOCHEMICAL PHARMACOLOGY 19(4):1341-& MCCARTHY JS; FURNER RL; VANDYKE K; STITZEL RE EFFECTS OF MALARIAL INFECTION ON HOST MICROSOMAL DRUG- METABOLIZING ENZYMES	30	0
451	2	291 1973 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 55(3):937-944 MOLDEUS P; GRUNDIN R; BAHR CV; ORRENIUS S SPECTRAL STUDIES ON DRUG-CYTOCHROME P-450 INTERACTION IN ISOLATED RAT-LIVER CELLS	30	8
452	8	420 1975 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 244(APR15):107-131 GRIFFIN BW; PETERSON JA; WERRINGLOER J; ESTABROOK RW CHEMISTRY OF SOLUBLE AND MEMBRANE-BOUND CYTOCHROME-P-450	30	10
453	8	433 1975 BIOCHEMICAL PHARMACOLOGY 24(19):1771-1776 POWIS G; BOOBIS AR EFFECT OF WASHING HEPATIC MICROSOMAL FRACTION IN SUCROSE SOLUTIONS AND IN SUCROSE SOLUTION CONTAINING EDTA UPON METABOLISM OF FOREIGN COMPOUNDS	30	2
454	6	511 1976 BIOCHEMICAL PHARMACOLOGY 25(1):100-103 CINTI DL; LEMELIN MA; CHRISTIAN J INDUCTION OF LIVER MICROSOMAL MIXED-FUNCTION OXIDASES BY VOLATILE HYDROCARBONS	30	1
455	3	661 1978 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 60(2):193-197 FORLIN L; LIDMAN U EFFECTS OF CLOPHEN A50, 4-TETRACHLOROBIPHENYL, 2,5,2',5'-TETRA- CHLOROBIPHENYL AND 2,4,5,2',4',5'-HEXACHLOROBIPHENYL ON MIXED- FUNCTION OXIDASE SYSTEM OF RAINBOW-TROUT (SALMO-GAIRDNERII RICH) LIVER	30	0
456	1	944 1983 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 222(2):590-598 MCCARTHY JL; KRAMER RE; FUNKENSTEIN B; SIMPSON ER; WATERMAN MR INDUCTION OF 17-ALPHA-HYDROXYLASE (CYTOCHROME P-45017-ALPHA) ACTIVITY BY ADRENOCORTICOTROPIN IN BOVINE ADRENOCORTICAL-CELLS MAINTAINED IN MONOLAYER-CULTURE	30	0
457	5	1053 1985 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 243(2):408-419 YEOWELL HN; LINKO P; HODGSON E; GOLDSTEIN JA INDUCTION OF SPECIFIC CYTOCHROME-P-450 ISOZYMES BY METHYLENEDIOXYPHENYL COMPOUNDS AND ANTAGONISM BY 3- METHYLCHOLANTHRENE	30	1
458	1	1355 1994 JOURNAL OF LIPID RESEARCH 35(3):361-372 OKUDA KI LIVER MITOCHONDRIAL P450 INVOLVED IN CHOLESTEROL CATABOLISM AND VITAMIN-D ACTIVATION	30	1
459	1	10 1968 BIOCHEMISTRY 7(6):2273-& HEINRICH.WL; COLAS A SELECTIVE STIMULATION INHIBITION AND PHYSICOCHEMICAL ALTERATION OF 7-AND 16ALPHA-HYDROXYLASES OF 3BETA-HYDROXYANDROST-5-EN-17- ONE AND DRUG-METABOLIZING ENZYMES IN HEPATIC MICROSOMAL FRACTIONS	29	0
460	1	153 1971 BIOCHEMICAL PHARMACOLOGY 20(9):2385-& ABERNATH.CO; HODGSON E; GUTHRIE FE STRUCTURE-ACTIVITY RELATIONSHIPS ON INDUCTION OF HEPATIC MICROSOMAL ENZYMES IN MOUSE BY 1,1,1-TRICHLORO-2,2-BIS(PARA CHLOROPHENYL) ETHANE(DDT) ANALOGS	29	0
461	3	166 1971 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 352(8):1048-& REINER O; UEHLEKE H CARBON TETRACHLORIDE INTERACTION WITH REDUCED MICROSOMAL CYTOCHROME P-450 AND HAEM	29	4
462	3	180 1971 MOLECULAR PHARMACOLOGY 7(3):280-& MITANI F; ALVARES AP; SASSA S; KAPPAS A PREPARATION AND PROPERTIES OF A SOLUBILIZED FORM OF CYTOCHROME P-450 FROM CHICK EMBRYO LIVER MICROSOMES	29	5
463	3	211 1972 BIOCHEMICAL PHARMACOLOGY 21(19):2577-& FLYNN EJ; ZANNONI VG; LYNCH M SPECIES DIFFERENCES AND DRUG-METABOLISM	29	1
464	7	331 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(24):8574-8584 MOLDEUS PW; CHA YN; CINTI DL; SCHENKMAN JB HEPATIC ORGANELLE INTERACTION .3. MITOCHONDRIAL MODIFICATION OF MICROSOMAL DRUG-METABOLISM	29	2
465	8	396 1974 LIFE SCIENCES 15(4):657-670 KUPFER D INTERACTIONS OF PROSTAGLANDINS WITH HEPATIC MICROSOMAL CYTOCHROME-P-450	29	7
466	2	426 1975 BIOCHEMICAL PHARMACOLOGY 24(12):227-233 JUCHAU MR; ZACHARIAH PK COMPARATIVE STUDIES ON OXIDATION AND REDUCTION OF DRUG SUBSTRATES IN HUMAN PLACENTAL VERSUS RAT HEPATIC MICROSOMES	29	2
467	4	613 1977 DRUG METABOLISM AND DISPOSITION 5(5):474-481 GURTOO HL; PARKER NB SEX-DEPENDENT REGULATION OF BENZO[A]PYRENE AND ZOXAZOLAMINE METABOLISM IN RAT TISSUES	29	1
468	8	690 1978 PHARMAZIE 33(6):325-328 REIN H; RISTAU O IMPORTANCE OF HIGH SPIN-LOW SPIN EQUILIBRIUM EXISTING IN CYTOCHROME-P-450 FOR ENZYMATIC MECHANISM	29	11
469	5	807 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(20):9685-9692 KOOP DR; HOLLENBERG PF KINETICS OF THE HYDROPEROXIDE-DEPENDENT DEALKYLATION REACTIONS CATALYZED BY RABBIT LIVER MICROSOMAL CYTOCHROME-P-450	29	2
470	1	859 1981 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 219(1):147-155 MUAKKASSAH SF; YANG WCT MECHANISM OF THE INHIBITORY-ACTION OF PHENELZINE ON MICROSOMAL DRUG-METABOLISM	29	1
471	3	986 1983 MOLECULAR PHARMACOLOGY 23(1):213-218 SABLJIC A; PROTICSABLJIC M QUANTITATIVE STRUCTURE-ACTIVITY STUDY ON THE MECHANISM OF INHIBITION OF MICROSOMAL PARA-HYDROXYLATION OF ANILINE BY ALCOHOLS - ROLE OF STERIC FACTORS	29	0
472	1	1002 1984 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 123(2):581-588 BEDNAR MM; SCHWARTZMAN M; IBRAHAM NG; MCGIFF JC; MULLANE KM CONVERSION OF ARACHIDONIC-ACID TO 2 NOVEL PRODUCTS BY A CYTOCHROME-P450-DEPENDENT MIXED-FUNCTION OXIDASE IN POLYMORPHONUCLEAR LEUKOCYTES	29	1
473	4	1035 1984 LIFE SCIENCES 35(26):2621-2626 LAKE BG; TREDGER JM; GRAY TJB; STUBBERFIELD CR; HODDER KD; GANGOLLI SD; WILLIAMS R THE EFFECT OF PEROXISOME PROLIFERATORS ON THE METABOLISM AND SPECTRAL INTERACTION OF ENDOGENOUS SUBSTRATES OF CYTOCHROME-P- 450 IN RAT HEPATIC MICROSOMES	29	0
474	2	1094 1985 XENOBIOTICA 15(7):591-597 DELMONTE M; CITTI L; GERVASI PG ISOPRENE METABOLISM BY LIVER MICROSOMAL MONOOXYGENASES	29	1
475	4	1165 1987 MOLECULAR PHARMACOLOGY 31(1):117-121 MURRAY M; ZALUZNY L; DANNAN GA; GUENGERICH FP; FARRELL GC ALTERED REGULATION OF CYTOCHROME-P-450 ENZYMES IN CHOLINE- DEFICIENT CIRRHOTIC MALE-RAT LIVER - IMPAIRED REGULATION AND ACTIVITY OF THE MALE-SPECIFIC ANDROST-4-ENE-3,17-DIONE 16- ALPHA-HYDROXYLASE, CYTOCHROME-P-450UT-A, IN HEPATIC CIRRHOSIS	29	1
476	2	1434 1999 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 266(3):690-698 Omura T Forty years of cytochrome P450	29	0
477	5	94 1970 EUROPEAN JOURNAL OF BIOCHEMISTRY 14(2):317-& KUPFER D; ORRENIUS S INTERACTION OF DRUGS, STEROIDS AND FATTY ACIDS WITH LIVER- MICROSOMAL CYTOCHROME P-450	28	10
478	3	102 1970 JAPANESE JOURNAL OF PHARMACOLOGY 20(2):194-& KATO R; ONODA K; SASAJIMA M EFFECTS OF MORPHINE TREATMENT AND STARVATION ON SUBSTRATE INTERACTION WITH P-450 IN OXIDATION OF DRUGS BY LIVER MICROSOMES	28	8
479	1	257 1972 MOLECULAR PHARMACOLOGY 8(2):197-& LORUSSO DJ; SUTTIE JW WARFARIN BINDING TO MICROSOMES ISOLATED FROM NORMAL AND WARFARIN-RESISTANT RAT-LIVER	28	0
480	1	312 1973 CHEMICO-BIOLOGICAL INTERACTIONS 6(4):249-257 BUNYAN PJ; PAGE JMJ PESTICIDE-INDUCED CHANGES IN HEPATIC MICROSOMAL ENZYME-SYSTEMS - SOME EFFECTS OF 1,1-DI(PARA-CHLOROPHENYL)-2,2- DICHLOROETHYLENE (DDE) AND 1,1-DI(PARA-CHLOROPHENYL)-2- CHLOROETHYLENE (DDMU) IN RAT AND JAPANESE-QUAIL	28	4
481	3	407 1974 TOXICOLOGY AND APPLIED PHARMACOLOGY 27(3):558-568 DEFERREY.EC; CASTRO JA; DIAZGOME.MI; DACOSTA N; DECASTRO CR; DEFENOS OM PREVENTION AND TREATMENT OF CARBON-TETRACHLORIDE HEPATOTOXICITY BY CYSTEINE - STUDIES ABOUT ITS MECHANISM	28	0
482	6	451 1975 CHEMICO-BIOLOGICAL INTERACTIONS 10(1):57-70 BROWN JE; KUPFER D INTERACTIONS OF HEME WITH HEPATIC MICROSOMAL MONOOXYGENASE EFFECT ON BENZPYRENE HYDROXYLATION	28	2
483	2	515 1976 BIOCHEMICAL PHARMACOLOGY 25(7):779-784 IVANETICH KM; BRADSHAW JJ; MARSH JA; KAMINSKY LS INTERACTION OF HEPATIC MICROSOMAL CYTOCHROME-P-450 WITH FLUROXENE (2,2,2-TRIFLUOROETHYL VINYL ETHER) INVITRO	28	5
484	2	563 1976 TOXICOLOGY AND APPLIED PHARMACOLOGY 35(3):491-499 DREW R; PRIESTLY BG MICROSOMAL DRUG-METABOLISM DURING ALPHA-NAPHTHYLISOTHIOCYANATE- INDUCED CHOLESTASIS	28	3
485	4	732 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(15):7238-7246 SWANSON RA; DUS KM SPECIFIC COVALENT LABELING OF CYTOCHROME P-450CAM WITH 1-(4- AZIDOPHENYL)IMIDAZOLE, AN INHIBITOR-DERIVED PHOTOAFFINITY PROBE FOR P-450 HEME-PROTEINS	28	6
486	6	914 1982 JAPANESE JOURNAL OF PHARMACOLOGY 32(1):9-21 MATSUBARA T; YOSHIHARA E; IWATA T; TOCHINO Y; HACHINO Y BIOTRANSFORMATION OF COUMARIN DERIVATIVES .1. 7-ALKOXYCOUMARIN ORTHO-DEALKYLASE IN LIVER-MICROSOMES	28	3
487	7	920 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(8):4063-4070 BACKES WL; HOGABOOM M; CANADY WJ THE TRUE HYDROPHOBICITY OF MICROSOMAL CYTOCHROME-P-450 IN THE RAT - SIZE DEPENDENCE OF THE FREE-ENERGY OF BINDING OF A SERIES OF HYDROCARBON SUBSTRATES FROM THE AQUEOUS PHASE TO THE ENZYME AND TO THE MEMBRANE AS DERIVED FROM SPECTRAL BINDING DATA	28	5
488	3	935 1982 XENOBIOTICA 12(5):303-313 SONAWANE BR; YAFFE SJ; WITMER CM EFFECTS OF ENDOTOXIN UPON RAT HEPATIC-MICROSOMAL DRUG- METABOLISM INVIVO AND INVITRO	28	0
489	6	1247 1990 BIOCHEMICAL PHARMACOLOGY 40(7):1645-1655 MAYER RT; NETTER KJ; HEUBEL F; HAHNEMANN B; BUCHHEISTER A; MAYER GK; BURKE MD 7-ALKOXYQUINOLINES - NEW FLUORESCENT SUBSTRATES FOR CYTOCHROME- P450 MONOOXYGENASES	28	2
490	1	1368 1995 FUNDAMENTAL AND APPLIED TOXICOLOGY 26(2):282-292 CHU I; VILLENEUVE DC; YAGMINAS A; LECAVALIER P; HAKANSSON H; AHLBORG UG; VALLI VE; KENNEDY SW; BERGMAN A; SEEGAL RF; FEELEY M TOXICITY OF PCB-77 (3,3',4,4'-TETRACHLOROBIPHENYL) AND PCB-118 (2,3',4,4',5-PENTACHLOROBIPHENYL) IN THE RAT FOLLOWING SUBCHRONIC DIETARY EXPOSURE	28	4
491	3	1397 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 347(2):181-192 Savas U; Carstens CP; Jefcoate CR Biological oxidations and P450 reactions - Recombinant mouse CYP1B1 expressed in Escherichia coli exhibits selective binding by polycyclic hydrocarbons and metabolism which parallels C3H10T1/2 cell microsomes, but differs from human recombinant CYP1B1	28	1
492	8	135 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 147(2):391-& NARASIMH.S SIGNIFICANCE OF STEROID-INDUCED TYPE 1 SPECTRAL CHANGE IN STEROID C-21 HYDROXYLASE SYSTEM OF BOVINE ADRENOCORTICAL MICROSOMES	27	0
493	5	537 1976 DRUG METABOLISM AND DISPOSITION 4(5):451-459 TREDGER JM; CHHABRA RS PRESERVATION OF VARIOUS MICROSOMAL DRUG-METABOLIZING COMPONENTS IN TISSUE PREPARATIONS FROM LIVERS, LUNGS, AND SMALL-INTESTINES OF RODENTS	27	2
494	2	543 1976 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 7(11):585-& AGOSIN M; NAQUIRA C; CAPDEVILA J; PAULIN J HEMOPROTEINS IN TRYPANOSOMA-CRUZI WITH EMPHASIS ON MICROSOMAL PIGMENTS	27	0
495	8	586 1977 BIOCHEMICAL PHARMACOLOGY 26(6):489-495 SUGIURA M; IWASAKI K; KATO R REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE-DEPENDENT REDUCTION OF TERTIARY AMINE N-OXIDE BY LIVER MICROSOMAL CYTOCHROME-P-450	27	2
496	4	692 1978 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 75(12):5955-5959 TSONG TY; YANG CS RAPID CONFORMATIONAL-CHANGES OF CYTOCHROME-P-450 - EFFECT OF DIMYRISTOYL LECITHIN	27	10
497	5	1023 1984 FUNDAMENTAL AND APPLIED TOXICOLOGY 4(2):134-143 COON MJ; KOOP DR; REEVE LE; CRUMP BL ALCOHOL METABOLISM AND TOXICITY - ROLE OF CYTOCHROME-P-450	27	1
498	3	1043 1984 TOXICOLOGY LETTERS 23(1):25-32 WHITE RD; NORTON R; BUS JS THE EFFECT OF BUTHIONINE SULFOXIMINE, AN INHIBITOR OF GLUTATHIONE SYNTHESIS, ON HEPATIC DRUG-METABOLISM IN THE MALE- MOUSE	27	1
499	1	1052 1985 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 238(2):588-595 BORRELLO S; MINOTTI G; PALOMBINI G; GRATTAGLIANO A; GALEOTTI T SUPEROXIDE-DEPENDENT LIPID-PEROXIDATION AND VITAMIN-E CONTENT OF MICROSOMES FROM HEPATOMAS WITH DIFFERENT GROWTH-RATES	27	2
500	4	1171 1987 XENOBIOTICA 17(1):1-9 VANDESTRAAT R; DEVRIES J; DEBOER HJR; VROMANS RM; VERMEULEN NPE RELATIONSHIP BETWEEN PARACETAMOL BINDING TO AND ITS OXIDATION BY 2 CYTOCHROMES-P-450 ISOZYMES - A PROTON NUCLEAR-MAGNETIC- RESONANCE AND SPECTROPHOTOMETRIC STUDY	27	3

Page 1:  1  2  3
Generated by: HistCite(Vlad). Version: 2003.05.01