#	Cited nodes	Nodes / Authors	GCS	LCS
101	5	478 1975 JOURNAL OF BIOLOGICAL CHEMISTRY 250(16):6445-6451 GRIFFIN BW; PETERSON JA PSEUDOMONAS-PUTIDA CYTOCHROME-P-450 - EFFECT OF COMPLEXES OF FERRIC HEMEPROTEIN ON RELAXATION OF SOLVENT WATER PROTONS	82	11
102	3	480 1975 JOURNAL OF PHARMACY AND PHARMACOLOGY 27(10):739-746 IOANNIDES C; PARKE DV MECHANISM OF INDUCTION OF HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYMES BY A SERIES OF BARBITURATES	169	11
103	8	690 1978 PHARMAZIE 33(6):325-328 REIN H; RISTAU O IMPORTANCE OF HIGH SPIN-LOW SPIN EQUILIBRIUM EXISTING IN CYTOCHROME-P-450 FOR ENZYMATIC MECHANISM	29	11
104	12	891 1982 BIOCHEMISTRY 21(6):1324-1330 BACKES WL; SLIGAR SG; SCHENKMAN JB KINETICS OF HEPATIC CYTOCHROME-P-450 REDUCTION - CORRELATION WITH SPIN STATE OF THE FERRIC HEME	50	11
105	13	1045 1984 XENOBIOTICA 14(1-2):27-47 GIBSON GG; TAMBURINI PP CYTOCHROME-P-450 SPIN STATE - INORGANIC BIOCHEMISTRY OF HEME IRON LIGATION AND FUNCTIONAL-SIGNIFICANCE	34	11
106	1	1 1967 BIOCHIMICA ET BIOPHYSICA ACTA 147(3):518-& ICHIKAWA Y; YAMANO T ROLE OF HYDROPHOBIC BONDING IN P-450 AND EFFECT OF ORGANIC COMPOUNDS ON CONVERSION OF P-450 TO P-420	47	10
107	1	30 1969 ANNUAL REVIEW OF BIOCHEMISTRY 38():21-& HAYAISHI O ENZYMIC HYDROXYLATION	128	10
108	6	81 1970 BIOCHEMICAL PHARMACOLOGY 19(5):1695-& TOPHAM JC RELATIONSHIP BETWEEN DIFFERENCE SPECTRA AND METABOLISM - BARBITURATES, DRUG INTERACTION AND SPECIES DIFFERENCE	23	10
109	5	94 1970 EUROPEAN JOURNAL OF BIOCHEMISTRY 14(2):317-& KUPFER D; ORRENIUS S INTERACTION OF DRUGS, STEROIDS AND FATTY ACIDS WITH LIVER- MICROSOMAL CYTOCHROME P-450	28	10
110	2	116 1970 LIFE SCIENCE PART 1 PHYSIOLOGY & PHARMACOLOGY 9(18):1039-& MATTHEWS HB; SKRINJAR.M; CASIDA JE INSECTICIDE SYNERGIST INTERACTIONS WITH CYTOCHROME-P-450 IN MOUSE LIVER MICROSOMES	36	10
111	5	176 1971 METABOLISM-CLINICAL AND EXPERIMENTAL 20(2):215-& GILLETTE JR EFFECT OF VARIOUS INDUCERS ON ELECTRON TRANSPORT SYSTEM ASSOCIATED WITH DRUG METABOLISM BY LIVER MICROSOMES	64	10
112	6	184 1971 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 270(1):41-& BOHN W; ULLRICH V; STAUDING.H SPECIES OF CYTOCHROME P-450 IN RAT LIVER MICROSOMES WITH DIFFERENT STEREOSELECTIVITY FOR BINDING AND MONOOXYGENATION OF (+)-METHYLPHENOBARBITAL AND (-)-METHYLPHENOBARBITAL	32	10
113	6	251 1972 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 183(1):206-& BEND JR; FOUTS JR; EASTERLI.RE; GRAM TE; HOOK GER COMPARATIVE STUDY OF HEPATIC AND PULMONARY MICROSOMAL MIXED- FUNCTION OXIDASE SYSTEMS IN RABBIT	145	10
114	6	253 1972 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 183(2):458-& FOUTS JR; DEVEREUX TR DEVELOPMENTAL ASPECTS OF HEPATIC AND EXTRAHEPATIC DRUG- METABOLIZING ENZYME-SYSTEMS - MICROSOMAL ENZYMES AND COMPONENTS IN RABBIT LIVVER AND LUNG DURING FIRST MONTH OF LIFE	100	10
115	5	292 1973 BIOCHEMICAL JOURNAL 134(2):367-375 CINTI DL; GRUNDIN R; ORRENIUS S EFFECT OF ETHANOL ON DRUG OXIDATIONS IN-VITRO AND SIGNIFICANCE OF ETHANOL-CYTOCHROME P-450 INTERACTION	61	10
116	8	420 1975 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 244(APR15):107-131 GRIFFIN BW; PETERSON JA; WERRINGLOER J; ESTABROOK RW CHEMISTRY OF SOLUBLE AND MEMBRANE-BOUND CYTOCHROME-P-450	30	10
117	3	505 1976 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 175(2):524-533 NORDBLOM GD; WHITE RE; COON MJ STUDIES ON HYDROPEROXIDE-DEPENDENT SUBSTRATE HYDROXYLATION BY PURIFIED LIVER MICROSOMAL CYTOCHROME-P-450	307	10
118	5	521 1976 BIOCHEMICAL PHARMACOLOGY 25(24):2747-2750 HOLDER GM; LITTLE PJ; RYAN AJ; WATSON TR INHIBITORS OF HEPATIC MIXED-FUNCTION OXIDASES .2. SOME BENZIMIDAZOLE, BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES	53	10
119	9	524 1976 BIOCHIMICA ET BIOPHYSICA ACTA 421(1):44-56 TSYRLOV IB; ZAKHAROVA NE; GROMOVA OA; LYAKHOVICH VV POSSIBLE MECHANISM OF INDUCTION OF LIVER MICROSOMAL MONOOXYGENASES BY PHENOBARBITAL	42	10
120	8	583 1977 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 78(4):1139-1146 PIERSON WC; CINTI DL TEMPERATURE-DEPENDENT AND TEMPERATURE-INDUCED SPECTRAL CHARACTERISTICS AND TRANSITIONS OF LIVER-MICROSOMES	20	10
121	4	692 1978 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 75(12):5955-5959 TSONG TY; YANG CS RAPID CONFORMATIONAL-CHANGES OF CYTOCHROME-P-450 - EFFECT OF DIMYRISTOYL LECITHIN	27	10
122	3	56 1969 JOURNAL OF BIOCHEMISTRY 66(5):739-& KATO R; TAKANAKA A; ONODA K SUBSTRATE INTERACTION WITH P-450 AND DRUG HYDROXYLATION BY LIVER MICROSOMES OF RATS UNDER PHYSIOLOGICALLY ABNORMAL STATES	18	9
123	3	118 1970 LIFE SCIENCES PT-2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY 9(20):1189-& YAFFE SJ PRESENCE OF A MONOOXYGENASE SYSTEM IN HUMAN FETAL LIVER MICROSOMES	160	9
124	8	190 1972 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 11(8):701-& ULLRICH V ENZYMATIC HYDROXYLATIONS WITH MOLECULAR-OXYGEN	144	9
125	9	195 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 153(1):294-& LU AYH; LEVIN W; WEST SB; KUNTZMAN R; JACOBSON M RECONSTITUTED LIVER MICROSOMAL ENZYME-SYSTEM THAT HYDROXYLATES DRUGS, OTHER FOREIGN COMPOUNDS, AND ENDOGENOUS SUBSTRATES .4. HYDROXYLATION OF ANILINE	50	9
126	6	224 1972 BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 8(3):186-& MAILMAN RB; HODGSON E CYTOCHROME-P-450 SUBSTRATE OPTICAL DIFFERENCE SPECTRA OF PESTICIDES WITH MOUSE HEPATIC MICROSOMES	18	9
127	1	255 1972 LIFE SCIENCES PT-2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY 11(5):247-& SCHENKMAN JB; CINTI DL HEPATIC MIXED FUNCTION OXIDASE ACTIVITY IN RAPIDLY PREPARED MICROSOMES	99	9
128	5	259 1972 MOLECULAR PHARMACOLOGY 8(3):327-& CINTI DL; SCHENKMAN JB HEPATIC ORGANELLE INTERACTION .1. SPECTRAL INVESTIGATION DURING DRUG BIOTRANSFORMATION	43	9
129	6	274 1972 XENOBIOTICA 2(3):259-& VAINIO H; HANNINEN O ENHANCEMENT OF ANILINE PARA HYDROXYLATION BY ACETONE IN RAT- LIVER MICROSOMES	39	9
130	10	280 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):156-174 LU AYH; LEVIN W; WEST S; JACOBSON M; RYAN D; KUNTZMAN R; CONNEY AH ROLE OF CYTOCHROME-P-450 AND P-448 IN DRUG AND STEROID HYDROXYLATIONS	44	9
131	3	368 1974 BIOCHEMICAL PHARMACOLOGY 23(21):3075-3078 CANADY WJ; ROBINSON DA; COLBY HD PARTITION MODEL FOR HEPATIC CYTOCHROME P-450-HYDROCARBON COMPLEX-FORMATION	12	9
132	2	393 1974 JOURNAL OF BIOLOGICAL CHEMISTRY 249(17):5373-5378 THOMPSON EA; SIITERI PK INVOLVEMENT OF HUMAN PLACENTAL MICROSOMAL CYTOCHROME-P-450 IN AROMATIZATION	450	9
133	21	401 1974 PHARMACOLOGICAL REVIEWS 26(3):171-197 CAMPBELL TC; HAYES JR ROLE OF NUTRITION IN DRUG-METABOLIZING ENZYME-SYSTEM	300	9
134	2	430 1975 BIOCHEMICAL PHARMACOLOGY 24(15):1427-1433 ELCOMBE CR; BRIDGES JW; GRAY TJB; NIMMOSMITH RH; NETTER KJ STUDIES ON INTERACTION OF SAFROLE WITH RAT HEPATIC MICROSOMES	71	9
135	9	438 1975 BIOCHEMICAL SOCIETY TRANSACTIONS 3(6):803-807 ULLRICH V; NASTAINCZYK W; RUF HH LIGAND REACTIONS OF CYTOCHROME-P-450	25	9
136	9	452 1975 CHEMICO-BIOLOGICAL INTERACTIONS 10(2):77-89 TSYRLOV IB; LYAKHOVICH VV RATE-LIMITING STEPS IN DRUG-METABOLISM BY MICROSOMES FROM CCL4- CIRRHOTIC RAT-LIVER	15	9
137	7	485 1975 MOLECULAR PHARMACOLOGY 11(4):450-461 JANSSON I; SCHENKMAN JB STUDIES ON 3 MICROSOMAL ELECTRON-TRANSFER ENZYME-SYSTEMS - EFFECTS OF ALTERATION OF COMPONENT ENZYME LEVELS INVIVO AND INVITRO	80	9
138	2	577 1977 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 180(2):363-373 PROUGH RA; ZIEGLER DM RELATIVE PARTICIPATION OF LIVER MICROSOMAL AMINE OXIDASE AND CYTOCHROME-P-450 IN N-DEMETHYLATION REACTIONS	153	9
139	4	650 1978 BIOCHEMICAL PHARMACOLOGY 27(8):1203-1209 LESCA P; LECOINTE P; PAOLETTI C; MANSUY D ELLIPTICINES AS POTENT INHIBITORS OF ARYL-HYDROCARBON HYDROXYLASE - THEIR BINDING TO MICROSOMAL CYTOCHROMES P450 AND PROTECTIVE EFFECT AGAINST BENZO(A)PYRENE MUTAGENICITY	78	9
140	7	674 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253(8):2804-2811 KUPFER D; NAVARRO J; PICCOLO DE HYDROXYLATION OF PROSTAGLANDINS-A1 AND E1 BY LIVER MICROSOMAL MONO-OXYGENASE - CHARACTERISTICS OF ENZYME-SYSTEM IN GUINEA-PIG	52	9
141	3	949 1983 BIOCHEMICAL PHARMACOLOGY 32(5):831-835 REILLY PEB; CARRINGTON LE; WINZOR DJ THE INTERACTION OF CIMETIDINE WITH RAT-LIVER MICROSOMES	54	9
142	9	965 1983 CHEMICO-BIOLOGICAL INTERACTIONS 45(2):243-258 BURKE MD; MAYER RT DIFFERENTIAL-EFFECTS OF PHENOBARBITONE AND 3-METHYLCHOLANTHRENE INDUCTION ON THE HEPATIC-MICROSOMAL METABOLISM AND CYTOCHROME P-450-BINDING OF PHENOXAZONE AND A HOMOLOGOUS SERIES OF ITS NORMAL-ALKYL ETHERS (ALKOXYRESORUFINS)	254	9
143	8	1008 1984 BIOCHEMISTRY 23(20):4526-4533 TAMBURINI PP; GIBSON GG; BACKES WL; SLIGAR SG; SCHENKMAN JB REDUCTION KINETICS OF PURIFIED RAT-LIVER CYTOCHROME-P-450 - EVIDENCE FOR A SEQUENTIAL REACTION-MECHANISM DEPENDENT ON THE HEMOPROTEIN SPIN STATE	40	9
144	2	96 1970 EUROPEAN JOURNAL OF PHARMACOLOGY 11(1):101-& ELING TE; HARBISON RD; BECKER BA; FOUTS J KINETIC CHANGES IN MICROSOMAL DRUG METABOLISM WITH AGE AND DIPHENYLHYDANTOIN TREATMENT	20	8
145	3	102 1970 JAPANESE JOURNAL OF PHARMACOLOGY 20(2):194-& KATO R; ONODA K; SASAJIMA M EFFECTS OF MORPHINE TREATMENT AND STARVATION ON SUBSTRATE INTERACTION WITH P-450 IN OXIDATION OF DRUGS BY LIVER MICROSOMES	28	8
146	2	115 1970 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 175(1):12-& GRAM TE; GUARINO AM; SCHROEDE.DH; DAVIS DC; REAGAN RL; GILLETTE JR EFFECT OF STARVATION ON KINETICS OF DRUG OXIDATION BY HEPATIC MICROSOMAL ENZYMES FROM MALE AND FEMALE RATS	59	8
147	2	127 1971 ANESTHESIOLOGY 35(3):241-& BROWN BR DIPHASIC ACTION OF HALOTHANE ON OXIDATIVE METABOLISM OF DRUGS BY LIVER - IN-VITRO STUDY IN RAT	49	8
148	2	145 1971 BIOCHEMICAL PHARMACOLOGY 20(6):1061-& AUST SD; STEVENS JB AMINOPYRINE DEMETHYLASE - MULTIPLICITY SHOWN BY DIELDRIN AND DDT INHIBITION	36	8
149	3	193 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 150(2):725-& PEISACH J; BLUMBERG WE; APPLEBY CA ELECTRON-PARAMAGNETIC RESONANCE AND TEMPERATURE DEPENDENT SPIN STATE STUDIES OF FERRIC CYTOCHROME-P-450 FROM RHIZOBIUM- JAPONICUM	43	8
150	1	271 1972 TOXICOLOGY AND APPLIED PHARMACOLOGY 22(1):50-& CHHABRA RS; FOUTS JR; GRAM TE COMPARATIVE STUDY OF 2 PROCEDURES USED IN DETERMINATION OF HEPATIC MICROSOMAL ANILINE HYDROXYLATION	59	8
151	2	291 1973 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 55(3):937-944 MOLDEUS P; GRUNDIN R; BAHR CV; ORRENIUS S SPECTRAL STUDIES ON DRUG-CYTOCHROME P-450 INTERACTION IN ISOLATED RAT-LIVER CELLS	30	8
152	15	381 1974 DRUG METABOLISM AND DISPOSITION 2(3):309-320 KULKARNI AP; MAILMAN RB; BAKER RC; HODGSON E CYTOCHROME-P-450 DIFFERENCE SPECTRA - TYPE-II INTERACTIONS IN INSECTICIDE-RESISTANT AND INSECTICIDE-SUSCEPTIBLE HOUSEFLIES	22	8
153	8	425 1975 BIOCHEMICAL JOURNAL 148(2):269-277 POWIS G EFFECT OF A SINGLE ORAL DOSE OF METHANOL, ETHANOL AND PROPAN-2- OL ON HEPATIC MICROSOMAL METABOLISM OF FOREIGN COMPOUNDS IN RAT	55	8
154	4	504 1976 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 172(2):696-705 MATSUBARA T; TOCHINO Y MODIFICATION BY CYANIDE OF ANILINE-BINDING REACTION WITH CYTOCHROME-P-450	18	8
155	5	516 1976 BIOCHEMICAL PHARMACOLOGY 25(8):951-955 GREINER JW; KRAMER RE; ROBINSON DA; CANADY WJ; COLBY HD INTERACTION OF AROMATIC-HYDROCARBONS AND DRUGS WITH ADRENAL MICROSOMAL CYTOCHROME-P-450 IN GUINEA-PIG	26	8
156	10	562 1976 TOXICOLOGY 5(3):297-309 LAKE BG; PHILLIPS JC; HEADING CE; GANGOLLI SD STUDIES ON INVITRO METABOLISM OF DIMETHYLNITROSAMINE BY RAT- LIVER	73	8
157	3	565 1976 TOXICOLOGY AND APPLIED PHARMACOLOGY 38(1):71-77 FABACHER DL; HODGSON E INDUCTION OF HEPATIC MIXED-FUNCTION OXIDASE ENZYMES IN ADULT AND NEONATAL MICE BY KEPONE AND MIREX	64	8
158	9	576 1977 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 179(1):34-42 POWIS G; JANSSON I; SCHENKMAN JB EFFECTS OF ALBUMIN UPON SPECTRAL CHANGES AND METABOLISM BY HEPATIC MICROSOMAL FRACTION	19	8
159	3	911 1982 GASTROENTEROLOGY 82(1):89-96 SPEEG KV; PATWARDHAN RV; AVANT GR; MITCHELL MC; SCHENKER S INHIBITION OF MICROSOMAL DRUG-METABOLISM BY HISTAMINE H2- RECEPTOR ANTAGONISTS STUDIED INVIVO AND INVITRO IN RODENTS	149	8
160	3	945 1983 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 225(2):758-770 KAMATAKI T; MAEDA K; YAMAZOE Y; NAGAI T; KATO R SEX DIFFERENCE OF CYTOCHROME-P-450 IN THE RAT - PURIFICATION, CHARACTERIZATION, AND QUANTITATION OF CONSTITUTIVE FORMS OF CYTOCHROME-P-450 FROM LIVER-MICROSOMES OF MALE AND FEMALE RATS	279	8
161	1	1352 1994 JOURNAL OF BIOCHEMICAL TOXICOLOGY 9(6):297-304 POON R; CHU I; LECAVALIER P; BERGMAN A; VILLENEUVE DC URINARY ASCORBIC-ACID - HPLC DETERMINATION AND APPLICATION AS A NONINVASIVE BIOMARKER OF HEPATIC RESPONSE	20	8
162	1	16 1968 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 349(11):1618-& NETTER KJ INHIBITION OF OXIDATIVE DRUG METABOLISM BY METYRAPONE	12	7
163	6	82 1970 BIOCHEMICAL PHARMACOLOGY 19(5):1729-& GURTOO HL; CAMPBELL TC A KINETIC APPROACH TO A STUDY OF INDUCTION OF RAT LIVER MICROSOMAL HYDROXYLASE AFTER PRETREATMENT WITH 3,4-BENZPYRENE AND AFLATOXIN-B1	31	7
164	4	95 1970 EUROPEAN JOURNAL OF BIOCHEMISTRY 15(3):531-& SIES H; BRAUSER B INTERACTION OF MIXED FUNCTION OXIDASE WITH ITS SUBSTRATES AND ASSOCIATED REDOX TRANSITIONS OF CYTOCHROME-P-450 AND PYRIDINE NUCLEOTIDES IN PERFUSED RAT LIVER	57	7
165	3	99 1970 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 351(8):913-& FROMMER U; ULLRICH V; STAUDING.H HYDROXYLATION OF ALIPHATIC COMPOUNDS BY LIVER MICROSOMES .2. EFFECT OF PHENOBARBITAL INDUCTION IN RATS ON SPECIFIC ACTIVITY AND CYTOCHROME P-450 SUBSTRATE BINDING SPECTRA	26	7
166	2	170 1971 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 176(1):11-& KUTT H; FOUTS JR DIPHENYLHYDANTOIN METABOLISM BY RAT LIVER MICROSOMES AND SOME OF EFFECTS OF DRUG OR CHEMICAL PRETREATMENT ON DIPHENYLHYDANTOIN METABOLISM BY RAT LIVER MICROSOMAL PREPARATIONS	89	7
167	6	181 1971 MOLECULAR PHARMACOLOGY 7(6):683-& GLAZER RI; SCHENKMAN JB; SARTOREL.AC IMMUNOCHEMICAL STUDIES ON ROLE OF REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE-CYTOCHROME-C (P-450) REDUCTASE IN DRUG OXIDATION	39	7
168	4	220 1972 BIOCHIMICA ET BIOPHYSICA ACTA 261(1):94-& WILSON BJ; ORRENIUS S STUDY OF MODIFIED TYPE II SPECTRAL CHANGE PRODUCED BY INTERACTION OF AGROCLAVINE WITH CYTOCHROME-P-450	13	7
169	4	288 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 158(2):597-604 ELLIN A; ORRENIUS S CYTOCHROME P-450K OF RAT-KIDNEY CORTEX MICROSOMES - FURTHER STUDIES ON ITS INTERACTION WITH FATTY-ACIDS	69	7
170	9	338 1973 MOLECULAR PHARMACOLOGY 9(4):470-485 CORREIA MA; MANNERIN.GJ REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE SYNERGISM OF REDUCED TRIPHOSPHOPYRIDINE NUCLEOTIDE-DEPENDENT MIXED-FUNCTION OXIDASE SYSTEM OF HEPATIC MICROSOMES .2. ROLE OF TYPE 1 DRUG-BINDING SITE OF CYTOCHROME-P-450	58	7
171	4	339 1973 MOLECULAR PHARMACOLOGY 9(6):840-845 JANSSON I; SCHENKMAN JB EVIDENCE AGAINST PARTICIPATION OF CYTOCHROME B5 IN HEPATIC MICROSOMAL MIXED-FUNCTION OXIDASE REACTION	34	7
172	8	396 1974 LIFE SCIENCES 15(4):657-670 KUPFER D INTERACTIONS OF PROSTAGLANDINS WITH HEPATIC MICROSOMAL CYTOCHROME-P-450	29	7
173	8	415 1975 ACTA BIOLOGICA ET MEDICA GERMANICA 34(11-1):1755-1766 MISSELWITZ R; JANIG GR; REIN H; BUDER E; ZIRWER D; RUCKPAUL K INTERACTION OF SUBSTRATES WITH CYTOCHROME-P-450 IN MICROSOMAL AND SOLUBILIZED FORM	24	7
174	3	429 1975 BIOCHEMICAL PHARMACOLOGY 24(8):867-870 ALGAILANY KAS; BRIDGES JW; NETTER KJ DEALKYLATION OF SOME PARA-NITROPHENYLALKYLETHERS AND THEIR ALPHA-DEUTERATED ANALOGS BY RAT-LIVER MICROSOMES	22	7
175	5	481 1975 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 6(3-4):419-425 ESTABROOK RW; MARTINEZZEDILLO G; YOUNG S; PETERSON JA; MCCARTHY J INTERACTION OF STEROIDS WITH LIVER MICROSOMAL CYTOCHROME-P-450 - GENERAL HYPOTHESIS	43	7
176	26	685 1978 PHARMACOLOGY 17(5):262-279 KUMAKI K; NEBERT DW SPECTRAL EVIDENCE FOR WEAK LIGAND IN SIXTH POSITION OF HEPATIC MICROSOMAL CYTOCHROME-P-450 LOW-SPIN FERRIC IRON INVIVO	19	7
177	10	706 1979 BIOCHEMICAL PHARMACOLOGY 28(1):37-41 VANDENBERG AP; NOORDHOEK J; KOOPMANKOOL E USE OF COMPETITIVE INHIBITION OF SUBSTRATE-BINDING TO CYTOCHROME P450 IN DETERMINATION OF SPECTRAL DISSOCIATION- CONSTANTS FOR SUBSTRATES WITH MULTIPLE TYPES OF BINDING, AS ILLUSTRATED WITH 1-BUTANOL	11	7
178	4	830 1981 ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE 251(1):26-38 NIEMEGEERS CJE; LEVRON JC; AWOUTERS F; JANSSEN PAJ INHIBITION AND INDUCTION OF MICROSOMAL-ENZYMES IN THE RAT - A COMPARATIVE-STUDY OF 4 ANTI-MYCOTICS - MICONAZOLE, ECONAZOLE, CLOTRIMAZOLE AND KETOCONAZOLE	86	7
179	7	865 1981 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 78(9):5362-5366 CAPDEVILA J; CHACOS N; WERRINGLOER J; PROUGH RA; ESTABROOK RW LIVER MICROSOMAL CYTOCHROME-P-450 AND THE OXIDATIVE-METABOLISM OF ARACHIDONIC-ACID	218	7
180	4	895 1982 BIOCHIMICA ET BIOPHYSICA ACTA 714(2):234-242 WEINER LM; GRITZAN NP; BAZHIN NM; LYAKHOVICH VV MICROSOMAL AND PHOTOCHEMICAL OXIDATION AND REDUCTION OF 1- PIPERIDINOANTHRAQUINONE	15	7
181	10	1265 1990 PHARMACOLOGICAL REVIEWS 42(2):85-101 MURRAY M; REIDY GF SELECTIVITY IN THE INHIBITION OF MAMMALIAN CYTOCHROMES-P-450 BY CHEMICAL-AGENTS	254	7
182	25	1267 1990 PHARMACOLOGY & THERAPEUTICS 45(2):153-239 RYAN DE; LEVIN W PURIFICATION AND CHARACTERIZATION OF HEPATIC-MICROSOMAL CYTOCHROME-P-450	358	7
183	3	8 1968 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 32(6):921-& WHYSNER JA; HARDING BW SUBSTRATE INTERACTION WITH CYTOCHROME P450 OF ADRENAL CORTICAL SUBMITOCHONDRIAL PARTICLES	16	6
184	1	14 1968 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 349(4):455-& KRATZ F; STAUDING.H COUMARIN-INDUCED SPECTRAL CHANGES IN RABBIT LIVER MICROSOMES	8	6
185	2	48 1969 ENDOCRINOLOGIA JAPONICA 16(6):653-& KATO R; TAKAHASH.A; OMORI Y EFFECT OF ANDROGEN AND ESTROGEN ON HYDROXYLATION OF STEROID HORMONES BY RAT LIVER MICROSOMES	24	6
186	5	108 1970 JOURNAL OF BIOLOGICAL CHEMISTRY 245(3):519-& NEBERT DW MICROSOMAL CYTOCHROMES B5 AND P450 DURING INDUCTION OF ARYL HYDROCARBON HYDROXYLASE ACTIVITY IN MAMMALIAN CELL CULTURE	54	6
187	2	167 1971 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 19(1):58-& SELL JL; DAVISON KL; PUYEAR RL ANILINE HYDROXYLASE, N-DEMETHYLASE, AND CYTOCHROME-P450 IN LIVER MICROSOMES OF HENS FED DDT AND DIELDRIN	16	6
188	8	172 1971 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 179(1):91-& FOUTS JR; POHL RJ FURTHER STUDIES ON EFFECTS OF METAL IONS ON RAT LIVER MICROSOMAL REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE- CYTOCHROME P-450 REDUCTASE	41	6
189	7	196 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 153(2):480-494 HRYCAY EG; OBRIEN PJ CYTOCHROME-P-450 AS A MICROSOMAL PEROXIDASE IN STEROID HYDROPEROXIDE REDUCTION	101	6
190	3	221 1972 BIOCHIMICA ET BIOPHYSICA ACTA 263(1):41-& REICHMAN LM; ROZANTZE.EG; ANNAEV B STUDIES OF MICROSOMAL CYTOCHROME-P-450 WITH ISOCYANIDE SPIN LABEL	23	6
191	10	284 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 157(1):7-22 HRYCAY EG; OBRIEN PJ MICROSOMAL ELECTRON-TRANSPORT .1. REDUCED NICOTINAMIDE ADENINE- DINUCLEOTIDE PHOSPHATE-CYTOCHROME-C REDUCTASE AND CYTOCHROME-P- 450 AS ELECTRON CARRIERS IN MICROSOMAL NADPH-PEROXIDASE ACTIVITY	68	6
192	2	290 1973 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 50(3):649-655 GURTOO HL BINDING OF AFLATOXIN-B1 AND ITS METABOLITES TO HEPATIC MICROSOMES	22	6
193	6	293 1973 BIOCHEMICAL PHARMACOLOGY 22(9):1005-1014 HAYES JR; MGBODILE MU; CAMPBELL TC EFFECT OF PROTEIN-DEFICIENCY ON INDUCIBILITY OF HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM .1. EFFECT ON SUBSTRATE INTERACTION WITH CYTOCHROME-P-450	57	6
194	4	359 1974 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 59(1):334-339 VONBAHR C; VADI H; GRUNDIN R; MOLDEUS P; ORRENIUS S SPECTRAL STUDIES ON RAPID UPTAKE AND SUBSEQUENT BINDING OF DRUGS TO CYTOCHROME-P-450 IN ISOLATED RAT-LIVER CELLS	25	6
195	5	387 1974 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 355(11):1341-1349 MANSUY D; DUPPEL W; RUF HH; ULLRICH V PHOSPHINES AS LIGANDS TO MICROSOMAL CYTOCHROME-P-450	32	6
196	4	423 1975 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 170(1):160-168 PROUGH RA; BURKE MD ROLE OF NADPH-CYTOCHROME-C REDUCTASE IN MICROSOMAL HYDROXYLATION REACTIONS	42	6
197	2	442 1975 BIOCHEMICAL SOCIETY TRANSACTIONS 3(6):970-972 DICKINS M; ELCOMBE CR; NIMMOSMITH RH; BRIDGES JW STRUCTURE-BINDING RELATIONSHIPS BETWEEN BENZIMIDAZOLES AND CYTOCHROME-P-450	17	6
198	4	462 1975 EUROPEAN JOURNAL OF BIOCHEMISTRY 51(2):511-519 SCHUSTER I; FLESCHURZ C; HELM I INTERACTION OF A LIPOPHILIC DRUG WITH DIFFERENT SITES OF RAT- LIVER MICROSOMES - EQUILIBRIUM STUDIES WITH A SUBSTITUTED PLEUROMUTILIN	32	6
199	10	535 1976 DRUG METABOLISM AND DISPOSITION 4(1):17-24 TREDGER JM; CHHABRA RS; FOUTS JR POSTNATAL-DEVELOPMENT OF MIXED-FUNCTION OXIDATION AS MEASURED IN MICROSOMES FROM SMALL-INTESTINE AND LIVER OF RABBITS	32	6
200	3	554 1976 LIFE SCIENCES 18(5):507-513 KUPFER D; NAVARRO J METABOLISM OF PROSTAGLANDIN-A1 BY HEPATIC MICROSOMAL MONOOXYGENASE P-450 SYSTEM IN GUINEA-PIG AND RAT	22	6

#	Cited nodes	Nodes / Authors	GCS	LCS
201	9	555 1976 LIFE SCIENCES 19(5):611-623 SCHENKMAN JB; JANSSON I; ROBIESUH KM MANY ROLES OF CYTOCHROME-B5 IN HEPATIC MICROSOMES	73	6
202	5	556 1976 MOLECULAR PHARMACOLOGY 12(2):322-334 SUGIURA M; IWASAKI K; KATO R REDUCTION OF TERTIARY AMINE N-OXIDES BY LIVER MICROSOMAL CYTOCHROME-P-450	69	6
203	10	574 1977 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 178(1):89-107 JANSSON I; SCHENKMAN JB STUDIES ON 3 MICROSOMAL ELECTRON-TRANSFER ENZYME-SYSTEMS .2. SPECIFICITY OF ELECTRON FLOW PATHWAYS	90	6
204	4	614 1977 EUROPEAN JOURNAL OF BIOCHEMISTRY 74(1):69-75 COOPER DY; SCHLEYER H; ROSENTHAL O; LEVIN W; LU AYH; KUNTZMAN R; CONNEY AH INHIBITION BY CO OF HEPATIC BENZO[A]PYRENE HYDROXYLATION AND ITS REVERSAL BY MONOCHROMATIC LIGHT	25	6
205	4	623 1977 JOURNAL OF BIOCHEMISTRY 82(5):1237-1246 IMAI Y; SATO R; IYANAGI T RATE-LIMITING STEP IN RECONSTITUTED MICROSOMAL DRUG HYDROXYLASE SYSTEM	56	6
206	9	629 1977 LIFE SCIENCES 20(6):1017-1026 GREINER JW; KRAMER RE; RUMBAUGH RC; COLBY HD DIFFERENTIAL CONTROL OF ADRENAL DRUG AND STEROID METABOLISM IN GUINEA-PIG	46	6
207	5	634 1977 PHARMACOLOGICAL RESEARCH COMMUNICATIONS 9(9):833-846 RAFFAELI E; FACINO RM; SALMONA M; PITRE D INVITRO BINDING AND METABOLISM OF IOPRONIC ACID BY RAT-LIVER MICROSOMES	14	6
208	4	662 1978 DRUG METABOLISM AND DISPOSITION 6(4):353-362 WARNER M; LAMARCA MV; NEIMS AH CHROMATOGRAPHIC AND ELECTROPHORETIC HETEROGENEITY OF CYTOCHROMES P-450 SOLUBILIZED FROM UNTREATED RAT-LIVER	114	6
209	13	700 1979 ACTA BIOLOGICA ET MEDICA GERMANICA 38(2-3):163-175 WERRINGLOER J; KAWANO S; ESTABROOK RW SPIN STATE TRANSITIONS OF LIVER MICROSOMAL CYTOCHROME-P-450	19	6
210	11	708 1979 BIOCHEMICAL PHARMACOLOGY 28(2):231-238 DICKINS M; ELCOMBE CR; MOLONEY SJ; NETTER KJ; BRIDGES JW FURTHER-STUDIES ON THE DISSOCIATION OF THE ISOSAFROLE METABOLITE-CYTOCHROME-P-450 COMPLEX	50	6
211	4	732 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(15):7238-7246 SWANSON RA; DUS KM SPECIFIC COVALENT LABELING OF CYTOCHROME P-450CAM WITH 1-(4- AZIDOPHENYL)IMIDAZOLE, AN INHIBITOR-DERIVED PHOTOAFFINITY PROBE FOR P-450 HEME-PROTEINS	28	6
212	9	755 1979 PROSTAGLANDINS 17(4):587-597 GREINER JW; KRAMER RE; COLBY HD INTERACTION OF PROSTAGLANDINS WITH ADRENAL MICROSOMAL CYTOCHROME-P-450 IN THE GUINEA-PIG	13	6
213	4	761 1979 TOXICOLOGY AND APPLIED PHARMACOLOGY 49(3):437-450 ELCOMBE CR; LECH JJ INDUCTION AND CHARACTERIZATION OF HEMOPROTEIN(S) P-450 AND MONOOXYGENATION IN RAINBOW-TROUT (SALMO-GAIRDNERI)	150	6
214	6	792 1980 CHEMICO-BIOLOGICAL INTERACTIONS 32(1-2):101-110 DELAFORGE M; IOANNIDES C; PARKE DV INHIBITION OF CYTOCHROME P-448 MIXED-FUNCTION OXIDASE ACTIVITY FOLLOWING ADMINISTRATION OF 9-HYDROXYELLIPTICINE TO RATS	31	6
215	3	875 1982 BIOCHEMICAL JOURNAL 203(1):161-168 GIBSON GG; ORTON TC; TAMBURINI PP CYTOCHROME-P-450 INDUCTION BY CLOFIBRATE - PURIFICATION AND PROPERTIES OF A HEPATIC CYTOCHROME-P-450 RELATIVELY SPECIFIC FOR THE 12-HYDROXYLATION AND 11-HYDROXYLATION OF DODECANOIC ACID (LAURIC-ACID)	242	6
216	1	910 1982 GASTROENTEROLOGY 82(1):84-88 KNODELL RG; HOLTZMAN JL; CRANKSHAW DL; STEELE NM; STANLEY LN DRUG-METABOLISM BY RAT AND HUMAN HEPATIC MICROSOMES IN RESPONSE TO INTERACTION WITH H2-RECEPTOR ANTAGONISTS	156	6
217	1	989 1983 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 19(1):1-10 GADHER P; MERCER EI; BALDWIN BC; WIGGINS TE A COMPARISON OF THE POTENCY OF SOME FUNGICIDES AS INHIBITORS OF STEROL 14-DEMETHYLATION	98	6
218	7	1017 1984 EUROPEAN JOURNAL OF BIOCHEMISTRY 139(2):235-246 TAMBURINI PP; MASSON HA; BAINS SK; MAKOWSKI RJ; MORRIS B; GIBSON GG MULTIPLE FORMS OF HEPATIC CYTOCHROME-P-450 - PURIFICATION, CHARACTERIZATION AND COMPARISON OF A NOVEL CLOFIBRATE-INDUCED ISOZYME WITH OTHER MAJOR FORMS OF CYTOCHROME-P-450	204	6
219	9	1047 1984 XENOBIOTICA 14(1-2):119-137 IOANNIDES C; LUM PY; PARKE DV CYTOCHROME-P-448 AND THE ACTIVATION OF TOXIC-CHEMICALS AND CARCINOGENS	106	6
220	6	1072 1985 DRUG METABOLISM AND DISPOSITION 13(2):156-162 MEREDITH CG; MALDONADO AL; SPEEG KV THE EFFECT OF KETOCONAZOLE ON HEPATIC OXIDATIVE DRUG-METABOLISM IN THE RAT INVIVO AND INVITRO	104	6
221	16	1156 1987 DRUG METABOLISM REVIEWS 18(1):55-81 MURRAY M MECHANISMS OF THE INHIBITION OF CYTOCHROME-P-450-MEDIATED DRUG OXIDATION BY THERAPEUTIC AGENTS	72	6
222	1	1329 1993 BIOCHEMISTRY 32(38):9875-9880 MCMILLAN K; MASTERS BSS OPTICAL-DIFFERENCE SPECTROPHOTOMETRY AS A PROBE OF RAT-BRAIN NITRIC-OXIDE SYNTHASE HEME-SUBSTRATE INTERACTION	122	6
223	1	39 1969 BIOCHEMICAL PHARMACOLOGY 18(8):1991-& TERRIERE LC; CHAN TM ENHANCEMENT OF RAT LIVER MICROSOMAL OXIDASES BY MAGNESIUM AND A HEAT-STABLE FACTOR FROM SOLUBLE FRACTION	24	5
224	3	43 1969 BIOCHEMISTRY 8(7):2975-& WILSON LD; OLDHAM SB; HARDING BW STUDIES ON ADRENAL CORTICAL CYTOCHROME P-450 .2. EFFECTS OF INHIBITORS OF 11BETA HYDROXYLATION ON ITS OPTICAL AND MAGNETIC PROPERTIES	24	5
225	1	77 1970 BIOCHEMICAL PHARMACOLOGY 19(3):895-& BECKING GC; MORRISON AB HEPATIC DRUG METABOLISM IN ZINC-DEFICIENT RATS	52	5
226	4	103 1970 JAPANESE JOURNAL OF PHARMACOLOGY 20(4):546-& KATO R; ONODA KI; TAKANAKA A SPECIES DIFFERENCE IN DRUG METABOLISM BY LIVER MICROSOMES IN ALLOXAN DIABETIC OR FASTED ANIMALS .1. ACTIVITY OF DRUG- METABOLIZING ENZYMES AND ELECTRON TRANSPORT SYSTEM	64	5
227	9	155 1971 BIOCHEMICAL PHARMACOLOGY 20(11):3125-& HANSEN AR; FOUTS JR COMPARISON OF EFFECTS OF BENZPYRENE ADMINISTRATION ON SOME HEPATIC MICROSOMAL MIXED-FUNCITION OXIDASES OF RATS AND MICE	25	5
228	3	180 1971 MOLECULAR PHARMACOLOGY 7(3):280-& MITANI F; ALVARES AP; SASSA S; KAPPAS A PREPARATION AND PROPERTIES OF A SOLUBILIZED FORM OF CYTOCHROME P-450 FROM CHICK EMBRYO LIVER MICROSOMES	29	5
229	2	187 1971 YAKUGAKU ZASSHI 91(1):142-& KAMATAKI T; FUKAZAWA H; KITAGAWA H STUDIES ON HEXOBARBITAL DIFFERENCE SPECTRUM WITH MICROSOMES FROM 3-METHYLCHOLANTHRENE TREATED RATS	5	5
230	4	223 1972 BIOKHIMIYA 37(3):548-& RAIKHMAN LM; ROZANTSE.EG; SHAPIRO AB; ANNAEV B MECHANISM OF FORMATION OF ENZYME - SUBSTRATE COMPLEXES IN MICROSOMAL HYDROXYLATING SYSTEM	10	5
231	3	243 1972 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 20(3):553-& SELL JL; POONACHA KB; DAVISON KL DECREASED ANILINE HYDROXYLASE-ACTIVITY IN JAPANESE-QUAIL DUE TO DIETARY DDT	9	5
232	7	263 1972 PATHOLOGIA EUROPAEA 7(1):43-& DENK H CHEMICAL STRUCTURE OF ENDOPLASMIC-RETICULUM AND FUNCTION OF MICROSOMAL BIOTRANSFORMATION SYSTEM OF LIVER-CELL OF RATS IN EXPERIMENTAL CHOLESTASE	15	5
233	3	266 1972 PHARMACOLOGICAL RESEARCH COMMUNICATIONS 4(3):185-& CASTRO JA; CASTRO CRD; FERREYRA EC; FENOS OMD; DIAZGOME.MI; DACOSTA N EFFECT OF CYSTAMINE ON MIXED-FUNCTION OXYGENASE SYSTEM FROM RAT-LIVER MICROSOMES AND ITS PREVENTIVE EFFECT ON DESTRUCTION OF CYTOCHROME-P-450 BY CARBON-TETRACHLORIDE	18	5
234	12	355 1974 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 160(1):230-245 HRYCAY EG; OBRIEN PJ MICROSOMAL ELECTRON-TRANSPORT .2. REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE-CYTOCHROME-B5 REDUCTASE AND CYTOCHROME-P-450 AS ELECTRON CARRIERS IN MICROSOMAL NADH-PEROXIDASE ACTIVITY	93	5
235	3	356 1974 ARCHIVES OF TOXICOLOGY 32(2):69-81 SCHMOLDT A; BENTHE HF; FRUHLING R INDUCTION OF RAT-LIVER ENZYMES BY POLYCHLORINATED BIPHENYLS (PCBS) IN DEPENDENCE ON DOSE AND CHLORINE CONTENT	31	5
236	4	384 1974 EUROPEAN JOURNAL OF BIOCHEMISTRY 46(2):351-360 MOLDEUS P; GRUNDIN R; VADI H; ORRENIUS S STUDY OF DRUG-METABOLISM LINKED TO CYTOCHROME-P-450 IN ISOLATED RAT-LIVER CELLS	109	5
237	3	397 1974 LIFE SCIENCES 15(8):1433-1442 SUGIURA M; IWASAKI K; NOGUCHI H; KATO R EVIDENCE FOR INVOLVEMENT OF CYTOCHROME-P-450 IN TIARAMIDE N- OXIDE REDUCTION	54	5
238	4	441 1975 BIOCHEMICAL SOCIETY TRANSACTIONS 3(6):967-970 ELCOMBE CR; BRIDGES J; NIMMOSMITH RH; WERRINGLOER J CUMENE HYDROPEROXIDE-MEDIATED FORMATION OF INHIBITED COMPLEXES OF METHYLENEDIOXYPHENYL COMPOUNDS WITH CYTOCHROME-P-450	24	5
239	2	465 1975 FEBS LETTERS 52(1):77-80 MATSUBARA T; TOCHINO Y INHIBITORY ACTION OF CYANIDE ON ANILINE HYDROXYLASE SYSTEM	19	5
240	14	473 1975 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 23(2):177-183 KULKARNI AP; MAILMAN RB; HODGSON E CYTOCHROME-P-450 OPTICAL DIFFERENCE SPECTRA OF INSECTICIDES - COMPARATIVE STUDY	26	5
241	9	496 1975 XENOBIOTICA 5(5):261-277 BURKE MD; BRIDGES JW; PARKE DV EFFECTS OF NONIONIC DETERGENT TWEEN 80 ON HEPATIC MICROSOMAL HYDROXYLATION	17	5
242	10	497 1975 XENOBIOTICA 5(6):357-376 BURKE MD; BRIDGES JW BIPHENYL HYDROXYLATIONS AND SPECTRALLY APPARENT INTERACTIONS WITH LIVER-MICROSOMES FROM HAMSTERS PRETREATED WITH PHENOBARBITONE AND 3-METHYLCHOLANTHRENE	38	5
243	1	514 1976 BIOCHEMICAL PHARMACOLOGY 25(4):477-481 KOUROUNAKIS P; SZABO S; SELYE H EFFECT OF FLUOROSTEROIDS ON DRUG RESPONSE AND METABOLISM	14	5
244	2	515 1976 BIOCHEMICAL PHARMACOLOGY 25(7):779-784 IVANETICH KM; BRADSHAW JJ; MARSH JA; KAMINSKY LS INTERACTION OF HEPATIC MICROSOMAL CYTOCHROME-P-450 WITH FLUROXENE (2,2,2-TRIFLUOROETHYL VINYL ETHER) INVITRO	28	5
245	31	750 1979 PHARMACOLOGY & THERAPEUTICS 7(2):203-244 SNYDER R; REMMER H CLASSES OF HEPATIC MICROSOMAL MIXED-FUNCTION OXIDASE INDUCERS	80	5
246	5	799 1980 FEBS LETTERS 115(1):31-34 LYAKHOVICH VV; POLYAKOVA NE; POPOVA VI; EREMENKO SI; OLKIN SE; WEINER LM AFFINITY MODIFICATION OF CYTOCHROME-P450 BY IODINE-CONTAINING STABLE IMINOXYL RADICAL	8	5
247	12	832 1981 BIOCHEMICAL PHARMACOLOGY 30(6):595-600 MORGAN ET; DEVINE M; SKETT P CHANGES IN THE RAT HEPATIC MIXED-FUNCTION OXIDASE SYSTEM ASSOCIATED WITH CHRONIC ETHANOL VAPOR INHALATION	56	5
248	20	864 1981 PHARMACOLOGY & THERAPEUTICS 12(1):133-158 BACKES WL; CANADY WJ METHODS FOR THE EVALUATION OF HYDROPHOBIC SUBSTRATE BINDING TO CYTOCHROME-P-450	18	5
249	7	920 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(8):4063-4070 BACKES WL; HOGABOOM M; CANADY WJ THE TRUE HYDROPHOBICITY OF MICROSOMAL CYTOCHROME-P-450 IN THE RAT - SIZE DEPENDENCE OF THE FREE-ENERGY OF BINDING OF A SERIES OF HYDROCARBON SUBSTRATES FROM THE AQUEOUS PHASE TO THE ENZYME AND TO THE MEMBRANE AS DERIVED FROM SPECTRAL BINDING DATA	28	5
250	7	964 1983 CHEMICO-BIOLOGICAL INTERACTIONS 43(3):341-351 MURRAY M; RYAN AJ THE BINDING TO OXIDIZED CYTOCHROMES P-450 AND INHIBITION OF MIXED-FUNCTION OXIDASES BY ARYL-SUBSTITUTED BENZIMIDAZOLES AND RELATED-COMPOUNDS	20	5
251	5	1029 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259(3):1655-1660 YOSHIDA Y; AOYAMA Y YEAST CYTOCHROME-P-450 CATALYZING LANOSTEROL 14-ALPHA- DEMETHYLATION .1. PURIFICATION AND SPECTRAL PROPERTIES	130	5
252	2	1198 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(33):17672-17677 JOHNSON EF; SCHWAB GE; VICKERY LE POSITIVE EFFECTORS OF THE BINDING OF AN ACTIVE SITE-DIRECTED AMINO STEROID TO RABBIT CYTOCHROME-P-450-3C	50	5
253	1	24 1968 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 259(3):221-& LANGE G HYDROXYLASE ACTIVITY AND HEMOPROTEIN CONTENT OF MICROSOMES FROM RABBIT LIVER	8	4
254	4	58 1969 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 170(2):347-& STRIPP B; GREENE FE; GILLETTE JR DISULFIRAM IMPAIRMENT OF DRUG METABOLISM BY RAT LIVER MICROSOMES	94	4
255	2	66 1969 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 263(2):281-& KORANSKY W; MAGOUR S; NOACK G; HERMANN RS INFLUENCE OF INDUCING AGENTS ON DRUG-OXIDISING AND OTHER REDOX ENZYMES IN LIVER	21	4
256	1	69 1969 SCIENCE 163(3873):1297-& SIH CJ ENZYMATIC MECHANISM OF STEROID HYDROXYLATION	46	4
257	3	85 1970 BIOCHEMICAL PHARMACOLOGY 19(8):2461-& CASTRO JA; GREENE FE; GIGON P; SASAME H; GILLETTE JR EFFECT OF ADRENALECTOMY AND CORTISONE ADMINISTRATION ON COMPONENTS OF LIVER MICROSOMAL MIXED FUNCTION OXYGENASE SYSTEM OF MALE RATS WHICH CATALYZES ETHYLMORPHINE METABOLISM	55	4
258	2	86 1970 BIOCHEMICAL PHARMACOLOGY 19(9):2639-& BECKING GC; MORRISON AB ROLE OF DIETARY MAGNESIUM IN METABOLISM OF DRUGS BY NADPH- DEPENDENT RAT LIVER MICROSOMAL ENZYMES	22	4
259	4	88 1970 BIOCHIMICA ET BIOPHYSICA ACTA 208(1):116-& KATO R; TAKAHASH.A; OMORI Y EFFECTS OF THYROXINE AND THYROIDECTOMY ON HYDROXYLATION OF TESTOSTERONE BY LIVER MICROSOMES FROM MALE AND FEMALE RATS	36	4
260	3	89 1970 BIOCHIMICA ET BIOPHYSICA ACTA 218(2):320-& VANLIER JE; SMITH LL STEROL METABOLISM .15. REARRANGEMENT OF CHOLESTEROL 20ALPHA- HYDROPEROXIDE BY BOVINE ADRENAL CORTEX MITOCHONDRIAL CYTOCHROME-P-450 PREPARATIONS	21	4
261	3	101 1970 JAPANESE JOURNAL OF PHARMACOLOGY 20(1):157-& KATO R; ONODA K; TAKAYANA.M SPECIES AND SEX DIFFERENCES IN SUBSTRATE-INDUCED SPECTRAL CHANGE OF P-450 IN RELATION TO ACTIVITY OF DRUG OXIDATION IN LIVER MICROSOMES	12	4
262	5	107 1970 JOURNAL OF BIOCHEMISTRY 68(5):613-& KATO R; TAKANAKA A; TAKAHASH.A EFFECT OF THYROID HORMONE ON SUBSTRATE INTERACTION WITH P-450 IN OXIDATION OF DRUGS BY LIVER MICROSOMES	41	4
263	3	166 1971 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 352(8):1048-& REINER O; UEHLEKE H CARBON TETRACHLORIDE INTERACTION WITH REDUCED MICROSOMAL CYTOCHROME P-450 AND HAEM	29	4
264	7	197 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 153(2):502-507 ANDERS MW EFFECT OF PHENOBARBITAL AND 3-METHYLCHOLANTHRENE ADMINISTRATION ON IN-VITRO ENHANCEMENT OF MICROSOMAL AROMATIC HYDROXYLATION	18	4
265	9	198 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 153(2):543-553 LEVIN W; LU AYH; RYAN D; WEST S; KUNTZMAN R; CONNEY AH PARTIAL-PURIFICATION AND PROPERTIES OF CYTOCHROMES P-450 AND P- 448 FROM RAT-LIVER MICROSOMES	67	4
266	3	208 1972 BIOCHEMICAL PHARMACOLOGY 21(15):2053-& JUCHAU MR; SYMMS KG ANILINE HYDROXYLATION IN HUMAN PLACENTA - MECHANISTIC ASPECTS	52	4
267	1	225 1972 CANCER CHEMOTHERAPY REPORTS PART 1 56(5):603-610 ALLEN LM; CREAVEN PJ IN-VITRO ACTIVATION OF ISOPHOSPHAMIDE (NSC-109724), A NEW OXAZAPHOSPHORINE, BY RAT-LIVER MICROSOMES	59	4
268	2	229 1972 CHEMICO-BIOLOGICAL INTERACTIONS 5(3):201-& KUPFER D; JANSSON I; ORRENIUS S SPECTRAL INTERACTIONS OF MARIHUANA CONSTITUENTS (CANNABINOIDS) WITH RAT-LIVER MICROSOMAL MONOOXYGENASE SYSTEM	24	4
269	2	238 1972 GASTROENTEROLOGY 63(5):837-& GREIM H; TRULZSCH D; SCHAFFNE.F; DRESSLER K; CZYGAN P; POPPER H; ROBOZ J; HUTTERER F MECHANISM OF CHOLESTASIS .5. BILE-ACIDS IN NORMAL RAT LIVERS AND IN THOSE AFTER BILE-DUCT LIGATION	170	4
270	7	286 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 158(2):544-555 GRUNDIN R; JAKOBSSO.S; CINTI DL INDUCTION OF MICROSOMAL ARYL HYDROCARBON (3,4- BENZO(ALPHA)PYRENE) HYDROXYLASE AND CYTOCHROME P-450K IN RAT- KIDNEY CORTEX .1. CHARACTERISTICS OF HYDROXYLASE SYSTEM	42	4
271	8	296 1973 BIOCHEMICAL PHARMACOLOGY 22(14):1717-1728 WILSON JT GROWTH-HORMONE MODULATION OF LIVER DRUG METABOLIC ENZYME- ACTIVITY IN RAT .1. EFFECT OF HORMONE ON CONTENT AND RATE OF REDUCTION OF MICROSOMAL CYTOCHROME-P-450	31	4
272	3	299 1973 BIOCHEMICAL PHARMACOLOGY 22(23):2989-2996 SCHMIDT HL; MOLLER MR; WEBER N SUBSTITUENT EFFECTS ON MICROSOMAL DEALKYLATION OF AROMATIC N- ALKYL, O-ALKYL AND S-ALKYL COMPOUNDS	14	4
273	2	305 1973 BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 9(1):4-9 RAO HRG; ANDERS MW INHIBITION OF MICROSOMAL DRUG-METABOLISM BY ANTICHOLINESTERASE INSECTICIDES	13	4
274	1	312 1973 CHEMICO-BIOLOGICAL INTERACTIONS 6(4):249-257 BUNYAN PJ; PAGE JMJ PESTICIDE-INDUCED CHANGES IN HEPATIC MICROSOMAL ENZYME-SYSTEMS - SOME EFFECTS OF 1,1-DI(PARA-CHLOROPHENYL)-2,2- DICHLOROETHYLENE (DDE) AND 1,1-DI(PARA-CHLOROPHENYL)-2- CHLOROETHYLENE (DDMU) IN RAT AND JAPANESE-QUAIL	28	4
275	4	319 1973 DRUG METABOLISM REVIEWS 2(1):1-32 GRAM TE COMPARATIVE ASPECTS OF MIXED-FUNCTION OXIDATION BY LUNG AND LIVER OF RABBITS	62	4
276	9	330 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(20):7263-7271 CHENG SC; HARDING BW SUBSTRATE-INDUCED DIFFERENCE SPECTRAL, ELECTRON-PARAMAGNETIC RESONANCE, AND ENZYMATIC PROPERTIES OF CHOLESTEROL-DEPLETED MITOCHONDRIAL CYTOCHROME-P-450 OF BOVINE ADRENAL-CORTEX	38	4
277	6	341 1973 PHARMACOLOGY 9(3):129-137 FELLER DR; LUBAWY WC INTERACTIONS OF HEXOBARBITAL ENANTIOMERS WITH RAT-LIVER MICROSOMES	15	4
278	7	348 1973 TOXICOLOGY AND APPLIED PHARMACOLOGY 26(3):398-406 GONASUN LM; WITMER C; KOCSIS JJ; SNYDER R BENZENE METABOLISM IN MOUSE LIVER-MICROSOMES	92	4
279	8	363 1974 BIOCHEMICAL PHARMACOLOGY 23(10):1467-1477 PATEL JM; PAWAR SS RIBOFLAVIN AND DRUG-METABOLISM IN ADULT MALE AND FEMALE RATS	38	4
280	15	364 1974 BIOCHEMICAL PHARMACOLOGY 23(12):1721-1731 HAYES JR; CAMPBELL TC EFFECT OF PROTEIN-DEFICIENCY ON INDUCIBILITY OF HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM .3. EFFECT OF 3- METHYLCHOLANTHRENE INDUCTION ON ACTIVITY AND BINDING KINETICS	38	4
281	3	378 1974 DRUG METABOLISM AND DISPOSITION 2(2):194-201 SYMMS KG; JUCHAU MR ANILINE HYDROXYLASE AND NITROREDUCTASE ACTIVITIES OF PARTIALLY PURIFIED CYTOCHROMES P-450 AND P-420, AND CYTOCHROME-B5 SOLUBILIZED FROM RABBIT HEPATIC MICROSOMES	31	4
282	6	390 1974 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 22(3):360-366 HODGSON E; TATE LG; KULKARNI AP; PLAPP FW MICROSOMAL CYTOCHROME-P-450 - CHARACTERIZATION AND POSSIBLE ROLE IN INSECTICIDE RESISTANCE IN MUSCA-DOMESTICA	38	4
283	3	399 1974 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 285(4):355-366 SCHULTEHERMANN R; LEBERL C; LANDGRAF H; KORANSKY W LIVER GROWTH AND MIXED-FUNCTION OXIDASE ACTIVITY - DOSE- DEPENDENT STIMULATORY AND INHIBITORY EFFECTS OF ALPHA- HEXACHLOROCYCLOHEXANE	26	4
284	7	444 1975 BIOCHIMICA ET BIOPHYSICA ACTA 410(1):32-44 CINTI DL; OZOLS J BINDING OF HOMOGENEOUS CYTOCHROME-B5 TO RAT-LIVER MICROSOMES - EFFECT ON N-DEMETHYLATION REACTIONS	23	4
285	2	448 1975 CHEMICAL & PHARMACEUTICAL BULLETIN 23(4):817-823 ARIYOSHI T; IDEGUCHI K; ISHIZUKA Y; IWASAKI K; ARAKAKI M RELATIONSHIP BETWEEN CHEMICAL-STRUCTURE AND ACTIVITY .1. EFFECTS OF NUMBER OF CHLORINE ATOMS IN CHLORINATED BENZENES ON COMPONENTS OF DRUG-METABOLIZING SYSTEM AND HEPATIC CONSTITUENTS	36	4
286	4	449 1975 CHEMICAL & PHARMACEUTICAL BULLETIN 23(4):824-830 ARIYOSHI T; IDEGUCHI K; IWASAKI K; ARAKAKI M RELATIONSHIP BETWEEN CHEMICAL-STRUCTURE AND ACTIVITY .2. INFLUENCES OF ISOMERS IN DICHLOROBENZENE, TRICHLOROBENZENE, AND TETRACHLOROBENZENE ON ACTIVITIES OF DRUG-METABOLIZING-ENZYMES	39	4
287	12	477 1975 JOURNAL OF BIOCHEMISTRY 78(4):785-794 YOSHIDA Y; KUMAOKA H STUDIES ON MICROSOMAL ELECTRON-TRANSPORT SYSTEM OF ANAEROBICALLY GROWN YEAST .3. SPECTRAL CHARACTERIZATION OF CYTOCHROME-P-450	23	4
288	5	494 1975 TOXICOLOGY AND APPLIED PHARMACOLOGY 34(1):102-114 DIAZGOMEZ MI; CASTRO CRD; DACOSTA N; FENOS OMD; FERREYRA ECD; CASTRO JA SPECIES-DIFFERENCES IN CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY - ROLE OF CCL4 ACTIVATION AND OF LIPID PEROXIDATION	41	4
289	14	510 1976 BIOCHEMICAL JOURNAL 160(1):75-83 TSYRLOV IB; GROMOVA OA; LYAKHOVICH VV MECHANISM OF INHIBITION BY CARBONYL CYANIDE META- CHLOROPHENYLHYDRAZONE AND SODIUM DEOXYCHOLATE OF CYTOCHROME P- 450-CATALYZED HEPATIC MICROSOMAL DRUG-METABOLISM	9	4
290	8	585 1977 BIOCHEMICAL PHARMACOLOGY 26(2):137-141 POWIS G; LYON L; MCKILLOP D NADH SYNERGISM OF MICROSOMAL ANILINE METABOLISM IN PRESENCE OF ENHANCING AGENTS	18	4
291	4	596 1977 BIOCHEMICAL PHARMACOLOGY 26(22):2117-2120 YIH TD; VANROSSUM JM KS-VALUES OF SOME HOMOLOGOUS SERIES OF BARBITURATES AND RELATIONSHIP WITH LIPOPHILICITY AND METABOLIC-CLEARANCE	35	4
292	1	597 1977 BIOCHEMICAL PHARMACOLOGY 26(22):2169-2173 LESCA P; LECOINTE P; PAOLETTI C; MANSUY D HYDROXYLATION OF ANTI-TUMOR AGENT, ELLIPTICINE, BY LIVER- MICROSOMES FROM DIFFERENTLY PRETREATED RATS	50	4
293	11	641 1978 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 185(1):251-261 JANSSON I; SCHENKMAN JB INFLUENCES OF SUBSTRATES OF DIFFERENT MICROSOMAL ELECTRON- TRANSFER PATHWAYS ON OXIDATION-REDUCTION KINETICS OF MICROSOMAL CYTOCHROME-B5	23	4
294	7	646 1978 BIOCHEMICAL PHARMACOLOGY 27(5):627-633 VANDENBERG AP; NOORDHOEK J; SAVENIJECHAPEL EM; KOOPMANKOOL E DEVELOPMENT OF SEX-DIFFERENCES IN DEMETHYLATION OF ETHYLMORPHINE AND IN ITS INTERACTION WITH COMPONENTS OF HEPATIC MICROSOMAL CYTOCHROME P450 SYSTEM IN MICE	22	4
295	2	649 1978 BIOCHEMICAL PHARMACOLOGY 27(7):1098-1101 ANDERS MW INHIBITION AND ENHANCEMENT OF MICROSOMAL DRUG-METABOLISM BY DIETHYL MALEATE	96	4
296	4	664 1978 EUROPEAN JOURNAL OF BIOCHEMISTRY 88(1):37-47 FEYEREISEN R; DURST F ECDYSTERONE BIOSYNTHESIS - MICROSOMAL CYTOCHROME-P-450-LINKED ECDYSONE 20-MONOOXYGENASE FROM TISSUES OF AFRICAN MIGRATORY LOCUST	91	4
297	25	687 1978 PHARMACOLOGY & THERAPEUTICS PART A-CHEMOTHERAPY TOXICOLOGY AND METABOLIC INHIBITORS 2(4):727-749 CINTI DL AGENTS ACTIVATING LIVER MICROSOMAL MIXED-FUNCTION OXIDASE SYSTEM	39	4
298	14	705 1979 BIOCHEMICAL PHARMACOLOGY 28(1):31-36 VANDENBERG AP; NOORDHOEK J; KOOPMANKOOL E RELATION BETWEEN SEX-DEPENDENCY OF TYPE-I BINDING OF ETHYLMORPHINE AND 1-BUTANOL-INDUCED SPECTRAL CHANGE IN MOUSE- LIVER MICROSOMES	5	4
299	2	714 1979 BIOCHEMICAL PHARMACOLOGY 28(12):1917-1921 CHA YN; BUEDING E EFFECT OF 2(3)-TERT-BUTYL-4-HYDROXYANISOLE ADMINISTRATION ON THE ACTIVITIES OF SEVERAL HEPATIC MICROSOMAL AND CYTOPLASMIC ENZYMES IN MICE	130	4
300	8	726 1979 DRUG METABOLISM REVIEWS 10(2):153-185 COOPER DY; SCHLEYER H; LEVIN SS; EISENHARDT RH; NOVACK BG; ROSENTHAL O A RE-EVALUATION OF THE ROLE OF CYTOCHROME-P-450 AS THE TERMINAL OXIDASE IN HEPATIC-MICROSOMAL MIXED-FUNCTION OXIDASE CATALYZED- REACTIONS	33	4

#	Cited nodes	Nodes / Authors	GCS	LCS
301	14	857 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256(14):7213-7227 BACKES WL; CANADY WJ THE INTERACTION OF HEPATIC CYTOCHROME-P-450 WITH ORGANIC- SOLVENTS - THE EFFECT OF ORGANIC-SOLVENTS ON APPARENT SPECTRAL BINDING CONSTANTS FOR HYDROCARBON SUBSTRATES	20	4
302	13	882 1982 BIOCHEMICAL PHARMACOLOGY 31(7):1315-1320 DICKINS M; BRIDGES JW THE RELATIONSHIP BETWEEN THE BINDING OF 2-NORMAL- ALKYLBENZIMIDAZOLES TO RAT HEPATIC-MICROSOMAL CYTOCHROME-P-450 AND THE INHIBITION OF MONOOXYGENATION	39	4
303	6	909 1982 FEBS LETTERS 150(1):219-222 ZIEGLER M; BLANCK J; RUCKPAUL K SPIN EQUILIBRIUM RELAXATION KINETICS OF CYTOCHROME-P450 LM2	14	4
304	8	926 1982 JOURNAL OF MEDICINAL CHEMISTRY 25(6):622-626 LITTLE PJ; RYAN AJ INHIBITORS OF HEPATIC MIXED-FUNCTION OXIDASES .4. EFFECTS OF BENZIMIDAZOLE AND RELATED-COMPOUNDS ON ARYL-HYDROCARBON HYDROXYLASE-ACTIVITY FROM PHENOBARBITONE AND 3- METHYLCHOLANTHRENE INDUCED RATS	23	4
305	3	934 1982 XENOBIOTICA 12(1):9-17 RENDIC S; ALEBICKOLBAH T; KAJFEZ F; RUF HH INTERACTION OF RANITIDINE WITH LIVER-MICROSOMES	65	4
306	8	1106 1986 BIOCHEMICAL PHARMACOLOGY 35(13):2157-2161 WINZOR DJ; IOANNONI B; REILLY PEB THE NATURE OF MICROSOMAL MONOOXYGENASE INHIBITION BY CIMETIDINE	19	4
307	5	1162 1987 JOURNAL OF PHARMACOBIO-DYNAMICS 10(7):287-295 MORITA K; KONISHI H; ONO T; SHIMAKAWA H A COMPARISON OF THE INHIBITORY EFFECTS OF ROXATIDINE ACETATE HYDROCHLORIDE AND CIMETIDINE ON CYTOCHROME-P-450-MEDIATED DRUG- METABOLISM IN MOUSE HEPATIC MICROSOMES AND IN MAN INVIVO	14	4
308	6	1199 1988 JOURNAL OF PHARMACOBIO-DYNAMICS 11(2):106-114 MORITA K; ONO T; SHIMAKAWA H INHIBITORY EFFECTS OF KETOCONAZOLE AND MICONAZOLE ON CYTOCHROME-P-450-MEDIATED OXIDATIVE-METABOLISM OF TESTOSTERONE AND XENOBIOTICS IN MOUSE HEPATIC MICROSOMES - COMPARATIVE-STUDY WITH CIMETIDINE	18	4
309	6	1274 1990 XENOBIOTICA 20(9):967-978 VROMANS RM; VANDESTRAAT R; GROENEVELD M; VERMEULEN NPE ONE-ELECTRON REDUCTION OF MITOMYCIN-C BY RAT-LIVER - ROLE OF CYTOCHROME-P-450 AND NADPH-CYTOCHROME-P-450 REDUCTASE	16	4
310	1	1281 1991 BIOCHEMICAL PHARMACOLOGY 42(3):702-704 HADASOVA E; SIEGMUND W; FRANKE G; SCHNEIDER T; BEYRICH A; BLEYER H; HUBNER G DRUG OXIDATION AND N-ACETYLATION IN RATS PRETREATED WITH SUBTOXIC DOSES OF STREPTOLYSIN-O	10	4
311	3	1320 1992 HEPATOLOGY 15(2):276-281 LEE SM; CLEMENS MG EFFECT OF ALPHA-TOCOPHEROL ON HEPATIC MIXED-FUNCTION OXIDASES IN HEPATIC ISCHEMIA REPERFUSION	23	4
312	1	1368 1995 FUNDAMENTAL AND APPLIED TOXICOLOGY 26(2):282-292 CHU I; VILLENEUVE DC; YAGMINAS A; LECAVALIER P; HAKANSSON H; AHLBORG UG; VALLI VE; KENNEDY SW; BERGMAN A; SEEGAL RF; FEELEY M TOXICITY OF PCB-77 (3,3',4,4'-TETRACHLOROBIPHENYL) AND PCB-118 (2,3',4,4',5-PENTACHLOROBIPHENYL) IN THE RAT FOLLOWING SUBCHRONIC DIETARY EXPOSURE	28	4
313	1	25 1968 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 261(2):152-& UEHLEKE H; GREIM H STIMULATION OF DRUG OXIDATION IN KIDNEY MICROSOMES BY PHENOBARBITAL	17	3
314	2	38 1969 BIOCHEMICAL PHARMACOLOGY 18(6):1501-& HLAVICA P; KIESE M N-OXYGENATION OF N-ALKYL- AND N,N-DIALKYLANILINES BY RABBIT LIVER MICROSOMES	37	3
315	1	57 1969 JOURNAL OF MEDICINAL CHEMISTRY 12(2):207-& MCMAHON RE; MILLS J; CULP HW; GIBSON WR; MILLER WM; MARSHALL FJ DEMETHYLATION STUDIES .6. INHIBITION OF HEPATIC MICROSOMAL OXYGENATION BY 2,4-DICHLORO(6-PHENYLPHENOXY)ETHYLAMINE AND RELATED COMPOUNDS	32	3
316	4	91 1970 CANCER RESEARCH 30(9):2346-& KATO R; TAKAHASH.A DECREASED HYDROXYLATION OF STEROID HORMONES BY LIVER MICROSOMES FROM RATS BEARING WALKER CARCINOSARCOMA-256	26	3
317	7	114 1970 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 174(2):211-& KATO R; TAKASHI A; OHSHIMA T; HOSOYA E EFFECT OF MORPHINE ADMINISTRATION ON HYDROXLYLATION OF STEROID HORMONES BY RAT LIVER MICROSOMES	31	3
318	3	136 1971 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 42(1):1-& RUBIN E; GANG H; LIEBER CS INTERACTION OF ETHANOL AND PYRAZOLE WITH HEPATIC MICROSOMES	53	3
319	1	140 1971 BIOCHEMICAL JOURNAL 123(5):815-& SLATER TF; SAWYER BC STIMULATORY EFFECTS OF CARBON TETRACHLORIDE ON PEROXIDATIVE REACTIONS IN RAT LIVER FRACTIONS IN-VITRO - INTERACTION SITES IN ENDOPLASMIC RETICULUM	84	3
320	2	148 1971 BIOCHEMICAL PHARMACOLOGY 20(7):1371-& GRAM TE; SCHROEDE.DH; DAVIS DC; REAGAN RL; GUARINO AM ENZYMIC AND BIOCHEMICAL COMPOSITION OF SMOOTH AND ROUGH MICROSOMAL MEMBRANES FROM MONKEY, GUINEA-PIG AND MOUSE LIVER	19	3
321	1	149 1971 BIOCHEMICAL PHARMACOLOGY 20(7):1569-& HANSEN LG; HODGSON E BIOCHEMICAL CHARACTERISTICS OF INSECT MICROSOMES - N- DEMETHYLATION AND O-DEMETHYLATION	82	3
322	1	200 1972 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 47(2):315-& CASTRO JA; CASTRO CRD; DACOSTA N; FERREYRA EC; FENOS OMD; DIAZGOME.MI CARBON-TETRACHLORIDE EFFECT ON RAT-LIVER AND ADRENALS RELATED TO THEIR MIXED-FUNCTION OXYGENASE CONTENT	36	3
323	4	201 1972 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 47(3):611-& KUPFER D; LEVIN E MONOOXYGENASE DRUG-METABOLIZING ACTIVITY IN CACL2-AGGREGATED HEPATIC MICROSOMES FROM RAT-LIVER	65	3
324	6	216 1972 BIOCHEMISTRY 11(6):955-& ROTH JA; NEAL RA SPECTRAL STUDIES OF BINDING OF O,O-DIETHYL PARA NITROPHENYLPHOSPHOROTHIONATE (PARATHION) TO CYTOCHROME-P-450	7	3
325	6	228 1972 CHEMICO-BIOLOGICAL INTERACTIONS 4(6):399-& PHILPOT RM; HODGSON E DIFFERENCES IN CYTOCHROME P-450S FROM RESISTANT AND SUSCEPTIBLE HOUSE-FLIES	15	3
326	2	239 1972 INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS 9(3):277-278 PATEL JM; PAWAR SS ACTIVITIES OF PHENOBARBITAL INDUCED LIVER MICROSOMAL ENZYMES IN RATS FED PROTEIN-FREE AND FAT-FREE DIETS	9	3
327	4	250 1972 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 182(2):320-& SOYKA LF; LONG RJ IN-VITRO INHIBITION OF DRUG-METABOLISM BY METABOLITES OF PROGESTERONE	40	3
328	2	264 1972 PEDIATRIC CLINICS OF NORTH AMERICA 19(1):37-& RANE A; SJOQVIST F DRUG-METABOLISM IN HUMAN FETUS AND NEWBORN INFANT	41	3
329	2	282 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):406-419 MASON JI; ESTABROO.RW; PURVIS JL TESTICULAR CYTOCHROME-P-450 AND IRON-SULFUR PROTEIN AS RELATED TO STEROID METABOLISM	57	3
330	5	297 1973 BIOCHEMICAL PHARMACOLOGY 22(19):2357-2364 PELKONEN O DRUG-METABOLISM AND DRUG-INDUCED SPECTRAL INTERACTIONS IN HUMAN FETAL LIVER-MICROSOMES	21	3
331	9	313 1973 CHEMICO-BIOLOGICAL INTERACTIONS 7(4):205-222 HOOK GER; BEND JR; FOUTS JR EFFECT OF SOME BIPHENYL SOLUBILIZING AND SUSPENDING AGENTS ON BIPHENYL 4-HYDROXYLASE OF RABBIT LIVER-MICROSOMES	13	3
332	3	323 1973 INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS 10(1):73-75 PATEL JM; PAWAR SS EFFECT OF RIBOFLAVIN DEFICIENCY ON LIVER MICROSOMAL ENZYME- SYSTEM AND LIPID PEROXIDATION IN MALE RATS	10	3
333	2	344 1973 RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY 5(3):635-645 GURTOO HL; DAVE C INTERACTION OF AFLATOXIN-B1 METABOLITE WITH RAT-LIVER RNA	24	3
334	2	370 1974 BIOCHEMICAL PHARMACOLOGY 23(24):3377-& BOOBIS AR; POWIS G EFFECTS OF CATECHOLAMINES UPON METABOLISM OF FOREIGN COMPOUNDS AND UPON DISTRIBUTION OF PERFUSATE IN ISOLATED LIVER OF RAT	15	3
335	8	377 1974 DRUG METABOLISM AND DISPOSITION 2(1):87-96 SOLIMAN MRI; JOHNSON HD; WADE AE INTERACTIONS OF INDUCERS, INHIBITORS, AND SUBSTRATES OF DRUG- METABOLIZING-ENZYMES WITH RAT-LIVER CYTOCHROME-P-450	23	3
336	5	394 1974 JOURNAL OF PEDIATRICS 85(4):534-542 ARANDA JV; MACLEOD SM; RENTON KW; EADE NR HEPATIC MICROSOMAL DRUG OXIDATION AND ELECTRON-TRANSPORT IN NEWBORN-INFANTS	64	3
337	4	398 1974 MOLECULAR PHARMACOLOGY 10(5):776-789 GURTOO HL; CAMPBELL TC METABOLISM OF AFLATOXIN-B1 AND ITS METABOLISM-DEPENDENT AND INDEPENDENT BINDING TO RAT HEPATIC MICROSOMES	48	3
338	6	404 1974 RADIATION RESEARCH 58(1):101-110 YUKAWA O; NAKAZAWA T DAMAGES IN MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM AFTER PARTIAL X-IRRADIATION OF RAT-LIVER	16	3
339	5	414 1975 ACTA BIOLOGICA ET MEDICA GERMANICA 34(8):1333-1337 MULLER D; LUBBE H; KLINGER W NADPH-DEPENDENT CYTOCHROME-P-450 REDUCTION IN LIVER-MICROSOMES OF RATS OF DIFFERENT AGES WITH AND WITHOUT PHENOBARBITAL PRETREATMENT	10	3
340	5	428 1975 BIOCHEMICAL PHARMACOLOGY 24(3):369-378 LIU SJ; RAMSEY RK; FALLON HJ EFFECTS OF ETHANOL ON HEPATIC MICROSOMAL DRUG-METABOLIZING- ENZYMES IN RAT	56	3
341	1	463 1975 EUROPEAN JOURNAL OF BIOCHEMISTRY 55(2):333-341 RICH PR; BENDALL DS CYTOCHROME COMPONENTS OF PLANT MICROSOMES	72	3
342	3	467 1975 FEBS LETTERS 60(2):294-299 GRASDALEN H; BACKSTROM D; ERIKSSON LEG; EHRENBERG A; MOLDEUS P; VONBAHR C; ORRENIUS S HETEROGENEITY OF CYTOCHROME-P-450 IN RAT-LIVER MICROSOMES - SELECTIVE INTERACTION OF METYRAPONE AND SKF 525-A WITH DIFFERENT FRACTIONS OF MICROSOMAL CYTOCHROME-P-450	22	3
343	7	519 1976 BIOCHEMICAL PHARMACOLOGY 25(19):2187-2195 BURKE MD; PROUGH RA SOME CHARACTERISTICS OF HAMSTER LIVER AND LUNG MICROSOMAL ARYL- HYDROCARBON (BIPHENYL AND BENZO(A)PYRENE) HYDROXYLATION REACTIONS	40	3
344	4	529 1976 CHEMICO-BIOLOGICAL INTERACTIONS 12(1):1-12 NAGATA C; FUJITA H; IMAMURA A MOLECULAR-ORBITAL STUDY ON INTERACTION BETWEEN CYTOCHROME-P-450 AND ITS SUBSTRATES	12	3
345	1	551 1976 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 198(3):709-715 GREINER JW; KRAMER RE; JARRELL J; COLBY HD MECHANISM OF ACTION OF SPIRONOLACTONE ON ADRENOCORTICAL FUNCTION IN GUINEA-PIGS	36	3
346	2	563 1976 TOXICOLOGY AND APPLIED PHARMACOLOGY 35(3):491-499 DREW R; PRIESTLY BG MICROSOMAL DRUG-METABOLISM DURING ALPHA-NAPHTHYLISOTHIOCYANATE- INDUCED CHOLESTASIS	28	3
347	7	575 1977 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 178(1):151-157 KITADA M; KAMATAKI T; KITAGAWA H NADH-SYNERGISM OF NADPH-DEPENDENT O-DEALKYLATION OF TYPE-2 COMPOUNDS, PARA-ANISIDINE AND PARA-PHENETIDINE, IN RAT-LIVER MICROSOMES	10	3
348	4	598 1977 BIOCHEMISTRY 16(4):593-600 UZGIRIS VI; GRAVES PE; SALHANICK HA LIGAND MODIFICATION OF CORPUS-LUTEUM MITOCHONDRIAL CYTOCHROME- P-450 SPECTRA AND CHOLESTEROL MONO-OXYGENATION - ASSAY OF ENZYME-SPECIFIC INHIBITORS	41	3
349	7	616 1977 GASTROENTEROLOGY 72(6):1232-1239 GUZELIAN PS; BISSELL DM; MEYER UA DRUG-METABOLISM IN ADULT RAT HEPATOCYTES IN PRIMARY MONOLAYER- CULTURE	207	3
350	2	628 1977 LIFE SCIENCES 20(6):991-997 MEHENDALE HM; TAKANAKA A; DESAIAH D; HO IK KEPONE INDUCTION OF HEPATIC MIXED-FUNCTION OXIDASES IN MALE RAT	49	3
351	3	630 1977 MOLECULAR PHARMACOLOGY 13(1):15-30 NOVAK RF; KAPETANOVIC IM; MIEYAL JJ NUCLEAR MAGNETIC-RESONANCE STUDIES OF SUBSTRATE-HEMOPROTEIN COMPLEXES IN SOLUTION .1. INTERACTION OF XYLIDINE WITH MYOGLOBIN, HEMOGLOBIN, AND CYTOCHROME P450	22	3
352	6	632 1977 MOLECULAR PHARMACOLOGY 13(6):1092-1104 IBA MM; SOYKA LF; SCHULMAN MP CHARACTERISTICS OF LIVER MICROSOMAL DRUG-METABOLIZING ENZYME- SYSTEM OF NEWBORN RATS	37	3
353	2	672 1978 JOURNAL OF BIOCHEMISTRY 83(4):1019-1027 FUKUSHIMA D; KIM YH; IYANAGI T; OAE S ENZYMATIC OXIDATION OF DISULFIDES AND THIOLSULFINATES BY BOTH RABBIT LIVER-MICROSOMES AND A RECONSTITUTED SYSTEM WITH PURIFIED CYTOCHROME-P-450	26	3
354	7	731 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(13):5641-5646 WOOD AW GENETIC-REGULATION OF COUMARIN HYDROXYLASE-ACTIVITY IN MICE - BIOCHEMICAL CHARACTERIZATION OF THE ENZYME FROM 2 INBRED STRAINS AND THEIR F1-HYBRID	52	3
355	13	749 1979 PHARMACOLOGY & THERAPEUTICS 6(3):551-577 DENK H EFFECT OF DETERGENTS ON THE MIXED-FUNCTION OXIDASE AND OTHER MICROSOMAL-ENZYMES	17	3
356	11	812 1980 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 214(1):80-86 HINES RN; PROUGH RA THE CHARACTERIZATION OF A INHIBITORY COMPLEX FORMED WITH CYTOCHROME-P-450 AND A METABOLITE OF 1,1-DISUBSTITUTED HYDRAZINES	40	3
357	3	863 1981 PHARMACOLOGICAL RESEARCH COMMUNICATIONS 13(9):819-828 BELANGER PM; ATITSEGBEASSOR A THE INHIBITORY EFFECT OF MONOAMINE-OXIDASE INHIBITORS ON HEPATIC MICROSOMAL-ENZYME SYSTEMS OF RAT-LIVER	16	3
358	3	879 1982 BIOCHEMICAL PHARMACOLOGY 31(6):907-913 LILIENBLUM W; WALLI AK; BOCK KW DIFFERENTIAL INDUCTION OF RAT-LIVER MICROSOMAL UDP- GLUCURONOSYLTRANSFERASE ACTIVITIES BY VARIOUS INDUCING AGENTS	187	3
359	8	901 1982 CHEMICO-BIOLOGICAL INTERACTIONS 42(3):279-289 DELAFORGE M; IOANNIDES C; PARKE DV SELECTIVE-INHIBITION OF THE SAFROLE-INDUCED MIXED-FUNCTION OXIDASE ACTIVITIES BY 9-HYDROXYELLIPTICINE	10	3
360	3	908 1982 FARMACO-EDIZIONE SCIENTIFICA 37(3):184-191 FACINO RM; CARINI M LOSS OF SUBSTRATE BINDING-CAPACITY OF THE HEPATIC-MICROSOMAL CYTOCHROME-P-450 IN FASCIOLA-HEPATICA INFECTED-RATS - TOXICOLOGICAL IMPLICATIONS	1	3
361	6	914 1982 JAPANESE JOURNAL OF PHARMACOLOGY 32(1):9-21 MATSUBARA T; YOSHIHARA E; IWATA T; TOCHINO Y; HACHINO Y BIOTRANSFORMATION OF COUMARIN DERIVATIVES .1. 7-ALKOXYCOUMARIN ORTHO-DEALKYLASE IN LIVER-MICROSOMES	28	3
362	4	921 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(8):4404-4411 JONEN HG; WERRINGLOER J; PROUGH RA; ESTABROOK RW THE REACTION OF PHENYLHYDRAZINE WITH MICROSOMAL CYTOCHROME-P- 450 - CATALYSIS OF HEME MODIFICATION	80	3
363	4	923 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(10):5496-5502 SONO M; DAWSON JH FORMATION OF LOW-SPIN COMPLEXES OF FERRIC CYTOCHROME P-450-CAM WITH ANIONIC LIGANDS - SPIN STATE AND LIGAND AFFINITY COMPARISON TO MYOGLOBIN	72	3
364	4	938 1982 XENOBIOTICA 12(8):517-526 GERVASI PG; CITTI L; TURCHI G; BELLUCCI G; BERTI G; MASTRORILLI E; TORTELLO MP THE METABOLISM OF 1,3-CYCLOHEXADIENE BY LIVER MICROSOMAL MONO- OXYGENASE	13	3
365	2	959 1983 BIOCHIMICA ET BIOPHYSICA ACTA 756(2):191-195 GOVINDWAR SP; KACHOLE MS; PAWAR SS PARTIAL INHIBITION OF HEPATIC-MICROSOMAL AMINOPYRINE N- DEMETHYLASE BY CAFFEINE IN PARTIALLY PURIFIED CYTOCHROME-P-450	10	3
366	2	1001 1984 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 118(3):916-922 TANIGUCHI H; IMAI Y; SATO R SUBSTRATE BINDING-SITE OF MICROSOMAL CYTOCHROME-P-450 DIRECTLY FACES MEMBRANE-LIPIDS	24	3
367	2	1004 1984 BIOCHEMICAL PHARMACOLOGY 33(4):687-689 MURRAY M; FARRELL GC DIFFERENT EFFECTS OF CARBON-TETRACHLORIDE TOXICITY AND CIRRHOSIS ON SUBSTRATE BINDING TO RAT HEPATIC-MICROSOMAL CYTOCHROME-P-450	18	3
368	1	1005 1984 BIOCHEMICAL PHARMACOLOGY 33(9):1451-1457 BULLEID NJ; CRAFT JA EFFECTS OF METYRAPONE AND NORHARMANE ON MICROSOMAL MONO- OXYGENASE AND EPOXIDE HYDROLASE ACTIVITIES	22	3
369	3	1078 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260(7):4007-4015 TAMBURINI PP; WHITE RE; SCHENKMAN JB CHEMICAL CHARACTERIZATION OF PROTEIN-PROTEIN INTERACTIONS BETWEEN CYTOCHROME-P-450 AND CYTOCHROME-B5	100	3
370	4	1081 1985 MOLECULAR PHARMACOLOGY 27(4):471-479 MORGAN ET; MACGEOCH C; GUSTAFSSON JA SEXUAL-DIFFERENTIATION OF CYTOCHROME-P-450 IN RAT-LIVER - EVIDENCE FOR A CONSTITUTIVE ISOZYME AS THE MALE-SPECIFIC 16- ALPHA-HYDROXYLASE	83	3
371	8	1092 1985 XENOBIOTICA 15(4):351-362 MARCUS CB; MURRAY M; WILKINSON CF SPECTRAL AND INHIBITORY INTERACTIONS OF METHYLENEDIOXYPHENYL AND RELATED-COMPOUNDS WITH PURIFIED ISOZYMES OF CYTOCHROME-P- 450	24	3
372	11	1109 1986 BIOCHEMICAL PHARMACOLOGY 35(24):4443-4448 BACKES WL; TURNER JL; HEIMANN TG; CANADY WJ ASSOCIATION OF HYDROPHOBIC SUBSTANCES WITH HEMIN - CHARACTERIZATION OF THE REVERSE TYPE-I BINDING SPECTRUM AND ITS RELATIONSHIP TO CYTOCHROME-P-450	5	3
373	4	1116 1986 CHEMICO-BIOLOGICAL INTERACTIONS 59(2):157-171 TESTAI E; VITTOZZI L BIOCHEMICAL-ALTERATIONS ELICITED IN RAT-LIVER MICROSOMES BY OXIDATION AND REDUCTION PRODUCTS OF CHLOROFORM METABOLISM	32	3
374	29	1118 1986 CRC CRITICAL REVIEWS IN BIOCHEMISTRY 20(2):139-200 WEINER LM MAGNETIC-RESONANCE STUDY OF THE STRUCTURE AND FUNCTIONS OF CYTOCHROME-P450	21	3
375	17	1140 1987 ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY 60():35-87 BLACK SD; COON MJ P-450 CYTOCHROMES - STRUCTURE AND FUNCTION	162	3
376	3	1160 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262(29):14319-14326 FAVREAU LV; MALCHOFF DM; MOLE JE; SCHENKMAN JB RESPONSES TO INSULIN BY 2 FORMS OF RAT HEPATIC-MICROSOMAL CYTOCHROME-P-450 THAT UNDERGO MAJOR (RLM6) AND MINOR (RLM5B) ELEVATIONS IN DIABETES	76	3
377	4	1171 1987 XENOBIOTICA 17(1):1-9 VANDESTRAAT R; DEVRIES J; DEBOER HJR; VROMANS RM; VERMEULEN NPE RELATIONSHIP BETWEEN PARACETAMOL BINDING TO AND ITS OXIDATION BY 2 CYTOCHROMES-P-450 ISOZYMES - A PROTON NUCLEAR-MAGNETIC- RESONANCE AND SPECTROPHOTOMETRIC STUDY	27	3
378	6	1172 1987 XENOBIOTICA 17(1):45-57 LAVRIJSEN K; VANHOUDT J; THIJS D; MEULDERMANS W; HEYKANTS J INTERACTION OF MICONAZOLE, KETOCONAZOLE AND ITRACONAZOLE WITH RAT-LIVER MICROSOMES	40	3
379	3	1213 1988 XENOBIOTICA 18(10):1109-1118 HODEK P; JANSCAK P; ANZENBACHER P; BURKHARD J; JANKU J; VODICKA L METABOLISM OF DIAMANTANE BY RAT-LIVER MICROSOMAL CYTOCHROMES-P- 450	21	3
380	7	1235 1989 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 33(1):33-39 KUHNVELTEN N; MEYER I; STAIB W SPECIFICITY OF STEROID BINDING TO TESTICULAR MICROSOMAL CYTOCHROME-P-450 - RELATION OF STEROID STRUCTURE TO TYPE-I SPECTRAL RESPONSES AFTER CORRECTION FOR HYDROPHOBIC ASSOCIATION WITH THE MEMBRANE	12	3
381	3	1284 1991 BIOCHIMICA ET BIOPHYSICA ACTA 1092(3):284-290 KALAPOS MP; GARZO T; ANTONI F; MANDL J EFFECT OF METHYLGLYOXAL ON GLUCOSE FORMATION, DRUG OXIDATION AND GLUTATHIONE CONTENT IN ISOLATED MURINE HEPATOCYTES	17	3
382	3	1308 1992 BIOCHEMICAL PHARMACOLOGY 43(2):343-352 GOEPTAR AR; TEKOPPELE JM; VANMAANEN JMS; ZOETEMELK CEM; VERMEULEN NPE ONE-ELECTRON REDUCTIVE BIOACTIVATION OF 2,3,5,6- TETRAMETHYLBENZOQUINONE BY CYTOCHROME-P450	22	3
383	2	1353 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(42):26083-26091 FREY C; NARAYANAN K; MCMILLAN K; SPACK L; GROSS SS; MASTERS BS; GRIFFITH OW L-THIOCITRULLINE - A STEREOSPECIFIC, HEME-BINDING INHIBITOR OF NITRIC-OXIDE SYNTHASES	70	3
384	3	1370 1995 IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 17(2):283-300 HADASOVA E; SIEGMUND W; WALTER R; SCHEUCH E; FRANKE G EFFECTS OF STREPTOLYSIN-O, PICIBANIL (OK-432) AND INTERFERON ALPHA-2A ON CYTOCHROME P-450-DEPENDENT MONOOXYGENASES AND ARYLAMINE N-ACETYLTRANSFERASE IN RAT-LIVER	8	3
385	3	1449 2000 BIOCHEMISTRY 39(20):5929-5939 Hosea NA; Miller GP; Guengerich FP Elucidation of distinct ligand binding sites for cytochrome P450 3A4	53	3
386	1	1457 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 393(2):255-261 Hanna IH; Kim MS; Guengerich FP Heterologous expression of cytochrome P450 2D6 mutants, electron transfer, and catalysis of bufuralol hydroxylation: The role of aspartate 301 in structural integrity	13	3
387	3	1460 2001 BIOCHEMISTRY 40(47):14215-14223 Miller GP; Hanna IH; Nishimura Y; Guengerich FP Oxidation of phenethylamine derivatives by cytochrome P450 2D6: The issue of substrate protonation in binding and catalysis	9	3
388	1	32 1969 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 134(2):308-& WITTKOP JA; PROUGH RA; REED DJ OXIDATIVE DEMETHYLATION OF N-METHYLHYDRAZINES BY RAT LIVER MICROSOMES	42	2
389	2	53 1969 JAPANESE JOURNAL OF PHARMACOLOGY 19(1):171-& KATO R; TAKANAKA A EFFECT OF PHENOBARBITAL AND METHYLCHOLANTHRENE TREATMENT ON DRUG-INDUCED DIFFERENCE SPECTRUM OF LIVER MICROSOMES	12	2
390	1	65 1969 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 262(3):375-& NETTER KJ ON HYDROXYLATION OF NAPHTHALENE BY LIVER MICROSOMES	3	2
391	1	70 1969 SCIENCE 165(3900):1371-& SHOEMAN DW; WHITE JG; MANNERIN.GJ CYTOCHROME P-420 - TUBULAR AGGREGATES FROM HEPATIC MICROSOMES	19	2
392	3	73 1970 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 40(4):858-& LIEBER CS; RUBIN E; DECARLI LM HEPATIC MICROSOMAL ETHANOL OXIDIZING SYSTEM (MEOS) - DIFFERENTIATION FROM ALCOHOL DEHYDROGENASE AND NADPH OXIDASE	51	2
393	2	75 1970 BIOCHEMICAL PHARMACOLOGY 19(1):27-& KAHL GF; NETTER KJ EFFECT OF METYRAPONE ON CELLULAR RESPIRATION AND MICROSOMAL DRUG OXIDATION	10	2
394	2	109 1970 JOURNAL OF BIOLOGICAL CHEMISTRY 245(16):4187-& HILTON J; SARTOREL.AC INDUCTION BY PHENOBARBITAL OF MICROSOMAL MIXED OXIDASE ENZYMES IN REGENERATING RAT LIVER	62	2
395	2	126 1971 ACTA PHARMACOLOGICA ET TOXICOLOGICA 29(2-3):284-& PELKONEN O; VORNE M; JOUPPILA P; KARKI NT METABOLISM OF CHLORPROMAZINE AND PARA NITROBENZOIC ACID IN LIVER, INTESTINE AND KIDNEY OF HUMAN FOETUS	60	2
396	2	157 1971 BIOCHIMICA ET BIOPHYSICA ACTA 252(2):348-& WILSON BJ; RAMSTAD E; JANSSON I; ORRENIUS S CONVERSION OF AGROCLAVINE BY MAMMALIAN CYTOCHROME P-450	8	2
397	3	160 1971 CHEMICAL & PHARMACEUTICAL BULLETIN 19(8):1749-& KAMATAKI T; KITADA M; KITAGAWA H SUBSTRATE INDUCED DIFFERENCE SPECTRUM OF MICROSOMAL P-450 IN HUMAN LIVER	3	2
398	3	168 1971 JOURNAL OF BIOCHEMISTRY 70(4):557-& ANDO N; HORIE S STUDIES ON P-450 .8. EFFECTS OF STEROIDS ON REACTION WITH OXYGEN AND RATE OF REDUCTION OF PARTIALLY PURIFIED P-450 FROM ADRENOCORTICAL MITOCHONDRIA	14	2
399	3	174 1971 LIFE SCIENCES PT-2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY 10(16):901-& LEWIS AM; BRYAN GT CYTOCHROME P450 AND STEROID 21-HYDROXYLATION IN MICROSOMES FROM HUMAN ADRENAL CORTEX	11	2
400	4	185 1971 PHARMACOLOGY 6(1):56-& STRIPP B; GREENE FE; GILLETTE JR EXTINCTION COEFFICIENTS FOR CYTOCHROME P-450 IN HEPATIC MICROSOMES FROM MALE AND FEMALE RATS	13	2

#	Cited nodes	Nodes / Authors	GCS	LCS
401	2	204 1972 BIOCHEMICAL JOURNAL 130(2):P70-& BURKE MD; BRIDGES JW INFLUENCE OF TWEEN 80 ON METABOLISM OF BIPHENYL MICROSOMAL OXYGENASES	5	2
402	6	207 1972 BIOCHEMICAL PHARMACOLOGY 21(11):1585-& BECKING GC INFLUENCE OF DIETARY IRON LEVELS ON HEPATIC DRUG-METABOLISM IN- VIVO AND IN-VITRO IN RAT	45	2
403	6	212 1972 BIOCHEMICAL PHARMACOLOGY 21(19):2652-& SOLIMAN MRI; WADE AE EFFECT OF PUROMYCIN ON BINDING AND ON METABOLISM IN-VITRO OF SUBSTRATES BY RAT-LIVER MICROSOMES	3	2
404	2	245 1972 JOURNAL OF BIOCHEMISTRY 71(5):915-& YOSHIDA Y; KUMAOKA H INTERCONVERSION OF HIGH-SPIN AND LOW-SPIN STATES OF CYTOCHROME P-450 SOLUBILIZED FROM YEAST MICROSOMES	18	2
405	1	252 1972 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 183(1):218-& GANG H; RUBIN E; LIEBER CS ANILINE HYDROXYLASE MICROASSAY SUITABLE FOR NEEDLE BIOPSY SPECIMENS - EFFECTS OF PHOSPHATE AND PYROPHOSPHATE ON ANILINE HYDROXYLATION	19	2
406	2	261 1972 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 272(3):277-& BREYER U PERAZINE, CHLORPROMAZINE AND IMIPRAMINE AS INDUCERS OF MICROSOMAL DRUG-METABOLISM	43	2
407	7	285 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 157(1):148-159 NEBERT DW; CONSIDIN.N; OWENS IS GENETIC EXPRESSION OF ARYL HYDROCARBON HYDROXYLASE INDUCTION .6. CONTROL OF OTHER AROMATIC HYDROCARBON-INDUCIBLE MONO- OXYGENASE ACTIVITIES AT OR NEAR SAME GENETIC LOCUS	72	2
408	3	295 1973 BIOCHEMICAL PHARMACOLOGY 22(12):1463-1476 MOFFITT AE; MURPHY SD EFFECT OF EXCESS AND DEFICIENT COPPER INTAKE ON RAT-LIVER MICROSOMAL ENZYME-ACTIVITY	43	2
409	10	309 1973 CHEMICAL & PHARMACEUTICAL BULLETIN 21(1):102-106 KAMATAKI T; SHIMOKAW.M; KITAGAWA H FURTHER STUDIES ON P-450 DIFFERENCE SPECTRA INDUCED BY VARIOUS COMPOUNDS IN LIVER-MICROSOMES FROM 3-METHYLCHOLANTHRENE TREATED RATS	8	2
410	6	314 1973 CLINICAL PHARMACOLOGY & THERAPEUTICS 14(4):666-672 RANE A; SJOQVIST F; ORRENIUS S DRUGS AND FETAL METABOLISM	53	2
411	4	318 1973 DRUG METABOLISM AND DISPOSITION 1(4):642-644 ANDERS MW; COOPER MJ; TAKEMORI AE KINETICS OF MICROSOMAL METABOLISM AND BINDING OF ENANTIOMERICALLY RELATED SUBSTRATES	7	2
412	6	327 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(1):9-14 WILSON LD; HARDING BW OXIDATION OF 20 ALPHA-HYDROXYCHOLESTEROL BY ADRENAL-CORTEX MITOCHONDRIA	17	2
413	7	331 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(24):8574-8584 MOLDEUS PW; CHA YN; CINTI DL; SCHENKMAN JB HEPATIC ORGANELLE INTERACTION .3. MITOCHONDRIAL MODIFICATION OF MICROSOMAL DRUG-METABOLISM	29	2
414	4	332 1973 JOURNAL OF NUTRITION 103(6):811-820 ANTHONY LE EFFECTS OF PROTEIN-CALORIE MALNUTRITION ON DRUG-METABOLISM IN RAT-LIVER MICROSOMES	31	2
415	2	343 1973 RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY 5(2):319-332 ROSS WE; SIMRELL C; OPPELT WW SEX-DEPENDENT EFFECTS OF CYCLIC-AMP ON HEPATIC MIXED-FUNCTION OXIDASE SYSTEM	19	2
416	3	349 1973 XENOBIOTICA 3(1):37-48 RANE A; BERGGREN M; YAFFE S; ERICSSON JL OXIDATIVE DRUG-METABOLISM IN PERINATAL RABBIT LIVER AND PLACENTA - BIOCHEMICAL AND MORPHOLOGIC STUDY	32	2
417	2	350 1973 XENOBIOTICA 3(6):357-366 JOSE PJ; SLATER TF STIMULATION OF LIPID PEROXIDATION PRODUCED BY DIMETHYLNITROSAMINE IN RAT-LIVER MICROSOMES IN-VITRO - EFFECTS OF PROMETHAZINE AND INHIBITORS OF DRUG-METABOLISM, AND A COMPARISON WITH PREVIOUS STUDIES USING CARBON-TETRACHLORIDE	14	2
418	2	351 1974 ACTA PHARMACOLOGICA ET TOXICOLOGICA 35(3):169-179 BORG KO; EKLUND B; SKANBERG I; WALLBORG M METABOLISM OF ALPRENOLOL IN LIVER-MICROSOMES, PERFUSED LIVER AND CONSCIOUS RAT	17	2
419	12	352 1974 ADVANCES IN CHEMISTRY SERIES (2):14-38 HODGSON E; KULKARNI AP INTERACTIONS OF PESTICIDES WITH CYTOCHROME-P-450	0	2
420	2	358 1974 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 57(2):426-433 MAY HE; BOOSE R; REED DJ HYDROXYLATION OF CARCINOSTATIC 1-(2-CHLOROETHYL)-3-CYCLOHEXYL- 1-NITROSOUREA (CCNU) BY RAT-LIVER MICROSOMES	71	2
421	3	369 1974 BIOCHEMICAL PHARMACOLOGY 23(22):3191-3197 JONSSON JA HYDROXYLATION OF AMPHETAMINE TO PARAHYDROXYAMPHETAMINE BY RAT- LIVER MICROSOMES	35	2
422	2	405 1974 RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY 9(1):107-118 GURTOO HL; DAHMS R NATURE OF BINDING OF AFLATOXIN-B2A TO RAT HEPATIC MICROSOMES	18	2
423	2	426 1975 BIOCHEMICAL PHARMACOLOGY 24(12):227-233 JUCHAU MR; ZACHARIAH PK COMPARATIVE STUDIES ON OXIDATION AND REDUCTION OF DRUG SUBSTRATES IN HUMAN PLACENTAL VERSUS RAT HEPATIC MICROSOMES	29	2
424	8	433 1975 BIOCHEMICAL PHARMACOLOGY 24(19):1771-1776 POWIS G; BOOBIS AR EFFECT OF WASHING HEPATIC MICROSOMAL FRACTION IN SUCROSE SOLUTIONS AND IN SUCROSE SOLUTION CONTAINING EDTA UPON METABOLISM OF FOREIGN COMPOUNDS	30	2
425	3	436 1975 BIOCHEMICAL SOCIETY TRANSACTIONS 3(1):183-185 LAKE BG; MINSKI MJ; PHILLIPS JC; HEADING CE; GANGOLLI SD; LLOYD AG COMPARATIVE STUDIES ON HEPATIC DIMETHYLNITROSAMINE DEMETHYLASE AND SOME XENOBIOTIC-METABOLIZING ENZYMES IN RAT	19	2
426	4	446 1975 CANCER RESEARCH 35(2):382-389 GURTOO HL; DAVE CV INVITRO METABOLIC CONVERSION OF AFLATOXINS AND BENZO(A)PYRENE TO NUCLEIC ACID-BINDING METABOLITES	89	2
427	6	447 1975 CANCER RESEARCH 35(8):2083-2091 VADI H; MOLDEUS P; CAPDEVILA J; ORRENIUS S METABOLISM OF BENZO(ALPHA-)PYRENE IN ISOLATED RAT-LIVER CELLS	63	2
428	6	451 1975 CHEMICO-BIOLOGICAL INTERACTIONS 10(1):57-70 BROWN JE; KUPFER D INTERACTIONS OF HEME WITH HEPATIC MICROSOMAL MONOOXYGENASE EFFECT ON BENZPYRENE HYDROXYLATION	28	2
429	3	457 1975 DOKLADY AKADEMII NAUK SSSR 223(1):237-240 TSYRLOV IB; ZAKHAROVA NE; LYAKHOVICH VV ROLE OF PRIMARY METABOLISM OF INDUCTOR IN MECHANISM OF 3- METHYLCHOLANETRENE AND PHENOBARBITAL ACTION	6	2
430	5	459 1975 DRUG METABOLISM AND DISPOSITION 3(2):104-112 KUBIC VL; ANDERS MW METABOLISM OF DIHALOMETHANES TO CARBON-MONOXIDE .2. INVITRO STUDIES	83	2
431	2	479 1975 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 41(1):7-12 NELSON EB; BRYAN GT STEROID HYDROXYLATIONS BY HUMAN ADRENAL-CORTEX MICROSOMES	23	2
432	2	482 1975 LIFE SCIENCES 17(10):1599-1606 LAKE BG; MINSKI MJ; PHILLIPS JC; GANGOLLI SD; LLOYD AG INVESTIGATIONS INTO HEPATIC-METABOLISM OF DIMETHYLNITROSAMINE IN RAT	11	2
433	1	493 1975 TOXICOLOGY AND APPLIED PHARMACOLOGY 33(1):94-105 ECOBICHON DJ; COMEAU AM ISOMERICALLY PURE CHLOROBIPHENYL CONGENERS AND HEPATIC FUNCTION IN RAT - INFLUENCE OF POSITION AND DEGREE OF CHLORINATION	43	2
434	3	501 1976 ACTA BIOLOGICA ET MEDICA GERMANICA 35(5):K19-K25 MISSELWITZ R; JANIG GR; REIN H; BUDER E; ZIRWER D; RUCKPAUL K DIFFERENTIATION BETWEEN TYPE-1 AND TYPE-2 SUBSTRATE BINDING TO CYTOCHROME-P-450 BY VARIATION OF TEMPERATURE	14	2
435	10	502 1976 ACTA BIOLOGICA ET MEDICA GERMANICA 35(5):627-633 MULLER D; KLINGER W BINDING OF HEXOBARBITAL AND ANILINE TO CYTOCHROME-P-450 OF LIVER-MICROSOMES FROM CONTROL AND PHENOBARBITAL-TREATED RATS OF DIFFERENT AGES	5	2
436	3	506 1976 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 72(1):216-222 GURTOO HL; PARKER NB ORGAN SPECIFICITY OF SEX DEPENDENT REGULATION OF ARYL- HYDROCARBON HYDROXYLASE (AHH) IN RAT	21	2
437	2	512 1976 BIOCHEMICAL PHARMACOLOGY 25(3):329-335 KHANNA JM; KALANT H; YEE Y; CHUNG S; SIEMENS AJ EFFECT OF CHRONIC ETHANOL TREATMENT ON METABOLISM OF DRUGS INVITRO AND INVIVO	64	2
438	2	520 1976 BIOCHEMICAL PHARMACOLOGY 25(19):2197-2201 POWIS G; GRANT L EFFECT OF INHIBITORS OF ALCOHOL METABOLISM UPON CHANGES IN HEPATIC MICROSOMAL METABOLISM OF FOREIGN COMPOUNDS PRODUCED BY ACUTE ADMINISTRATION OF SOME ALCOHOLS TO RAT	25	2
439	5	536 1976 DRUG METABOLISM AND DISPOSITION 4(3):208-214 CHHABRA RS; FOUTS JR BIOCHEMICAL PROPERTIES OF SOME MICROSOMAL XENOBIOTIC- METABOLIZING ENZYMES IN RABBIT SMALL-INTESTINE	26	2
440	5	537 1976 DRUG METABOLISM AND DISPOSITION 4(5):451-459 TREDGER JM; CHHABRA RS PRESERVATION OF VARIOUS MICROSOMAL DRUG-METABOLIZING COMPONENTS IN TISSUE PREPARATIONS FROM LIVERS, LUNGS, AND SMALL-INTESTINES OF RODENTS	27	2
441	4	542 1976 INSECT BIOCHEMISTRY 6(6):615-620 BRATTSTEN LB; WILKINSON CF; ROOT MM MICROSOMAL HYDROXYLATION OF ANILINE IN SOUTHERN ARMYWORM, SPODOPTERA-ERIDANIA	17	2
442	7	545 1976 JOURNAL OF BIOCHEMISTRY 79(5):1077-1087 MIYAKE Y; TAKAYAMA N SPECTRAL INTERMEDIATES DURING REDUCTION OF HEPATIC MICROSOMAL CYTOCHROME-P-450	2	2
443	3	550 1976 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 196(2):501-509 LAUTERBURG BH; BIRCHER J EXPIRATORY MEASUREMENT OF MAXIMAL AMINOPYRINE DEMETHYLATION INVIVO - EFFECT OF PHENOBARBITAL, PARTIAL-HEPATECTOMY, PORTACAVAL-SHUNT AND BILE-DUCT LIGATION IN RAT	168	2
444	2	557 1976 MUTATION RESEARCH 35(3):415-422 GUTTENPLAN JB; HUTTERER F; GARRO AJ EFFECTS OF CYTOCHROME P-448 AND P-450 INDUCERS ON MICROSOMAL DIMETHYLNITROSAMINE DEMETHYLASE ACTIVITY AND CAPACITY OF ISOLATED MICROSOMES TO ACTIVATE DIMETHYLNITROSAMINE TO A MUTAGEN	51	2
445	15	567 1976 XENOBIOTICA 6(6):363-375 COX PJ; KING LJ; PARKE DV BINDING OF TRICHLOROFLUOROMETHANE AND OTHER HALOALKANES TO CYTOCHROME-P-450 UNDER AEROBIC AND ANAEROBIC CONDITIONS	22	2
446	2	568 1976 XENOBIOTICA 6(11):679-689 HLAVICA P; KEHL M COMPARATIVE STUDIES ON N-OXIDATION OF ANILINE AND N,N- DIMETHYLANILINE BY RABBIT LIVER-MICROSOMES	15	2
447	8	586 1977 BIOCHEMICAL PHARMACOLOGY 26(6):489-495 SUGIURA M; IWASAKI K; KATO R REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE-DEPENDENT REDUCTION OF TERTIARY AMINE N-OXIDE BY LIVER MICROSOMAL CYTOCHROME-P-450	27	2
448	6	606 1977 CHEMICO-BIOLOGICAL INTERACTIONS 19(2):185-195 VANDENBERG AP; NOORDHOEK J; SAVENIJECHAPEL EM; KOOPMANKOOL E SEX-DEPENDENT AND STRAIN-DEPENDENT HEPATIC MICROSOMAL ETHYLMORPHINE N-DEMETHYLATION IN MICE - ROLES OF TYPE-I BINDING AND NADPH-CYTOCHROME P-450 REDUCTASE	11	2
449	5	619 1977 JAPANESE JOURNAL OF PHARMACOLOGY 27(5):601-608 KITADA M; CHIBA K; KAMATAKI T; KITAGAWA H INHIBITION BY CYANIDE OF DRUG OXIDATIONS IN RAT-LIVER MICROSOMES	22	2
450	8	620 1977 JAPANESE JOURNAL OF PHARMACOLOGY 27(5):701-708 MATSUBARA T; TOUCHI A HEPATIC AMINOPYRINE N-DEMETHYLASE SYSTEM - EFFECT OF CYANIDE ON MICROSOMAL N-DEMETHYLASE ACTIVITY	8	2
451	6	627 1977 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 8(6):669-675 HODGSON E; JUCHAU MR LIGAND-BINDING TO HUMAN PLACENTAL CYTOCHROME-P-450 - INTERACTION OF STEROIDS AND HEME-BINDING LIGANDS	21	2
452	6	631 1977 MOLECULAR PHARMACOLOGY 13(1):60-69 MONTGOMERY MR; CINTI DL PYRIDINE NUCLEOTIDE-DEPENDENT ELECTRON-TRANSPORT IN KIDNEY CORTEX MICROSOMES - INTERACTION WITH DESATURASE AND OTHER MICROSOMAL MIXED-FUNCTION OXIDASES	19	2
453	1	688 1978 PHARMAZIE 33(6):308-309 RUCKPAUL K 20 YEARS INVESTIGATIONS ON CYTOCHROME-P-450	6	2
454	3	695 1978 TOXICOLOGY AND APPLIED PHARMACOLOGY 44(1):171-180 MEHENDALE HM; TAKANAKA A; DESAIAH D; HO IK EFFECT OF PREEXPOSURE TO KEPONE ON HEPATIC MIXED-FUNCTION OXIDASES IN FEMALE RAT	22	2
455	5	698 1978 TOXICOLOGY AND APPLIED PHARMACOLOGY 46(2):315-321 FERNANDEZ G; VILLARRUEL MC; CASTRO JA MECHANISM OF DRUG-METABOLIZING-ENZYMES INDUCTION BY 2- DIETHYLAMINOETHYL-2-2-DIPHENYLVALERATE-HCL (SKF525A)	18	2
456	7	702 1979 ACTA BIOLOGICA ET MEDICA GERMANICA 38(2-3):483-494 SIPAL Z; ANZENBACHER P; PUTZ Z; CHLUMSKY J; KRIVANOVA O INTERACTION OF CYTOCHROME-P-450 WITH HYDROCARBONS	10	2
457	2	715 1979 BIOCHEMICAL PHARMACOLOGY 28(13):1993-2000 KAMATAKI T; SUGIURA M; YAMAZOE Y; KATO R PURIFICATION AND PROPERTIES OF CYTOCHROME-P-450 AND NADPH- CYTOCHROME-C (P-450) REDUCTASE FROM HUMAN-LIVER MICROSOMES	41	2
458	5	721 1979 CHEMICO-BIOLOGICAL INTERACTIONS 28(1):17-33 APPEL KE; RUF HH; MAHR B; SCHWARZ M; RICKART R; KUNZ W BINDING OF NITROSAMINES TO CYTOCHROME-P-450 OF LIVER-MICROSOMES	50	2
459	6	738 1979 LIFE SCIENCES 25(12):1085-1089 ANDERS MW; GANDER JE ACETONE ENHANCEMENT OF CUMENE HYDROPEROXIDE SUPPORTED MICROSOMAL ANILINE HYDROXYLATION	10	2
460	2	768 1980 AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 29(2):234-238 CHA YN; BYRAM JE; HEINE HS; BUEDING E EFFECT OF SCHISTOSOMA-MANSONI INFECTION ON HEPATIC DRUG- METABOLIZING CAPACITY OF ATHYMIC NUDE-MICE	17	2
461	4	790 1980 CHEMICO-BIOLOGICAL INTERACTIONS 31(3):279-286 SCHULTEHERMANN R; PARZEFALL W ADAPTIVE RESPONSES OF RAT-LIVER TO THE GESTAGEN AND ANTI- ANDROGEN CYPROTERONE-ACETATE AND OTHER INDUCERS .1. INDUCTION OF DRUG-METABOLIZING-ENZYMES	23	2
462	3	803 1980 INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 37(6):621-631 YUKAWA O; NAKAZAWA T RADIATION-INDUCED LIPID-PEROXIDATION AND MEMBRANE-BOUND ENZYMES IN LIVER-MICROSOMES	57	2
463	5	807 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(20):9685-9692 KOOP DR; HOLLENBERG PF KINETICS OF THE HYDROPEROXIDE-DEPENDENT DEALKYLATION REACTIONS CATALYZED BY RABBIT LIVER MICROSOMAL CYTOCHROME-P-450	29	2
464	1	818 1980 PEDIATRIC RESEARCH 14(8):939-942 SONAWANE BR; YAFFE SJ GRAM-NEGATIVE ENDOTOXIN ADMINISTRATION DECREASES HEPATIC DRUG- METABOLIZING-ENZYMES DURING DEVELOPMENT IN RATS	8	2
465	8	823 1980 RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY 29(3):561-571 WEINER M THE KINETICS OF INHIBITION OF HEPATIC DRUG-METABOLISM BY PROSTAGLANDINS IN RABBITS	12	2
466	3	827 1980 XENOBIOTICA 10(6):435-445 ELOVAARA E; COLLAN Y; PFAFFLI P; VAINIO H THE COMBINED TOXICITY OF TECHNICAL GRADE XYLENE AND ETHANOL IN THE RAT	32	2
467	10	831 1981 BIOCHEMICAL PHARMACOLOGY 30(1):19-24 BAST A; NOORDHOEK J PRODUCT INHIBITION DURING THE HEPATIC-MICROSOMAL N- DEMETHYLATION OF AMINOPYRINE IN THE RAT	17	2
468	3	844 1981 CANCER RESEARCH 41(1):120-124 GARRO AJ; SEITZ HK; LIEBER CS ENHANCEMENT OF DIMETHYLNITROSAMINE METABOLISM AND ACTIVATION TO A MUTAGEN FOLLOWING CHRONIC ETHANOL-CONSUMPTION	167	2
469	11	846 1981 CHEMICO-BIOLOGICAL INTERACTIONS 37(1-2):181-190 HACHINO Y; MATSUBARA T; HAGIHARA B PH-DEPENDENT INTERACTION OF MICROSOMAL CYTOCHROME-P-450 WITH SUBSTRATES .1. EFFECT OF PH UPON THE INTERACTION OF EXOGENOUS SUBSTRATES WITH MEMBRANE-BOUND CYTOCHROME-P-450	4	2
470	8	852 1981 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 362(8):1091-1099 MULLERENOCH D; SATO N; THOMAS H O-DEMETHYLATION OF SCOPARONE AND STUDIES ON THE SCOPARONE- INDUCED SPECTRAL CHANGE OF CYTOCHROME-P-450 IN RAT-LIVER MICROSOMES	17	2
471	2	866 1981 RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY 33(1):81-93 DREW R; ROWELL J; GRYGIEL JJ CIMETIDINE - A SPECIFIC INHIBITOR OF HEPATIC ARYL-HYDROCARBON HYDROXYLASE (AHH) IN THE RAT	24	2
472	9	878 1982 BIOCHEMICAL PHARMACOLOGY 31(3):311-317 BIDLACK WR; LOWERY GL MULTIPLE-DRUG METABOLISM - PARA-NITROANISOLE REVERSAL OF ACETONE ENHANCED ANILINE HYDROXYLATION	15	2
473	3	883 1982 BIOCHEMICAL PHARMACOLOGY 31(7):1393-1400 JORDAN RA; SCHENKMAN JB RELATIONSHIP BETWEEN MALONDIALDEHYDE PRODUCTION AND ARACHIDONATE CONSUMPTION DURING NADPH-SUPPORTED MICROSOMAL LIPID-PEROXIDATION	55	2
474	8	884 1982 BIOCHEMICAL PHARMACOLOGY 31(9):1795-1798 LITTLE PJ; RYAN AJ INHIBITORS OF HEPATIC MIXED-FUNCTION OXIDASES .5. INHIBITION OF AMINOPYRINE N-DEMETHYLATION AND ENHANCEMENT OF ANILINE HYDROXYLATION BY BENZOXAZOLE DERIVATIVES	4	2
475	4	886 1982 BIOCHEMICAL PHARMACOLOGY 31(11):1993-1998 POPOVA VI; LEONOVA IN; WEINER LM; SALGANIK RI INTERACTION OF THE SUBSTRATE-ANALOG OF CYTOCHROME-P-450 AND MIXED-FUNCTION OXIDASES	8	2
476	6	889 1982 BIOCHEMICAL PHARMACOLOGY 31(17):2745-2753 BAST A; NOORDHOEK J SPECTRAL INTERACTION OF ORPHENADRINE AND ITS METABOLITES WITH OXIDIZED AND REDUCED HEPATIC-MICROSOMAL CYTOCHROME-P-450 IN THE RAT	36	2
477	7	890 1982 BIOCHEMICAL PHARMACOLOGY 31(18):3002-3005 MURRAY M; RYAN AJ INHIBITION AND ENHANCEMENT OF MIXED-FUNCTION OXIDASES BY NITROGEN-HETEROCYCLES	20	2
478	2	898 1982 CANCER RESEARCH 42(7):2609-2615 CHA YN; HEINE HS COMPARATIVE EFFECTS OF DIETARY ADMINISTRATION OF 2(3)-TERT- BUTYL-4-HYDROXYANISOLE AND 3,5-DI-TERT-BUTYL-4-HYDROXYTOLUENE ON SEVERAL HEPATIC ENZYME-ACTIVITIES IN MICE AND RATS	135	2
479	17	904 1982 CRC CRITICAL REVIEWS IN BIOCHEMISTRY 12(1):39-101 HLAVICA P BIOLOGICAL OXIDATION OF NITROGEN IN ORGANIC-COMPOUNDS AND DISPOSITION OF N-OXIDIZED PRODUCTS	47	2
480	16	928 1982 PHARMACOLOGY & THERAPEUTICS 16(3):377-429 KLINGER W BIOTRANSFORMATION OF DRUGS AND OTHER XENOBIOTICS DURING POSTNATAL-DEVELOPMENT	58	2
481	1	952 1983 BIOCHEMICAL PHARMACOLOGY 32(20):3005-3009 EMEROLE GO; THABREW MI CHANGES IN SOME RAT HEPATIC-MICROSOMAL COMPONENTS INDUCED BY PROLONGED ADMINISTRATION OF CHLOROQUINE	23	2
482	5	955 1983 BIOCHEMICAL PHARMACOLOGY 32(24):3823-3829 ROSENBERG DW; DRUMMOND GS DIRECT INVITRO EFFECTS OF BIS(TRI-N-BUTYLTIN)OXIDE ON HEPATIC CYTOCHROME-P-450	22	2
483	2	956 1983 BIOCHEMICAL SOCIETY TRANSACTIONS 11(6):663-665 MERCER EI INHIBITION OF STEROL 14-ALPHA-DEMETHYLASE ENZYMES	13	2
484	6	979 1983 JAPANESE JOURNAL OF PHARMACOLOGY 33(5):1065-1075 MATSUBARA T; OTSUBO S; YOSHIHARA E LIVER MICROSOMAL CYTOCHROME-P-450-DEPENDENT O-DEALKYLATION REACTION IN VARIOUS ANIMALS	17	2
485	4	990 1983 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 19(1):44-52 RIVIERE JL PROCHLORAZ, A POTENT INDUCER OF THE MICROSOMAL CYTOCHROME-P-450 SYSTEM	31	2
486	14	996 1983 XENOBIOTICA 13(12):707-714 MURRAY M; RYAN AJ THE INTERACTION OF ARYLALKYLBENZIMIDAZOLES AND RELATED- COMPOUNDS WITH MICROSOMAL OXIDATION	17	2
487	2	1003 1984 BIOCHEMICAL PHARMACOLOGY 33(1):115-123 MELTZER NM; STANG P; STERNSON LA; WADE AE INFLUENCE OF TAMOXIFEN AND ITS N-DESMETHYL AND 4-HYDROXY METABOLITES ON RAT-LIVER MICROSOMAL-ENZYMES	35	2
488	2	1025 1984 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 365(7):773-779 KUHNVELTEN N; BUNSE T; SCHURER N; STAIB W DIRECT EFFECT OF ANDROGENS ON PROGESTERONE BINDING AND METABOLISM IN RAT TESTIS MICROSOMES	7	2
489	1	1052 1985 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 238(2):588-595 BORRELLO S; MINOTTI G; PALOMBINI G; GRATTAGLIANO A; GALEOTTI T SUPEROXIDE-DEPENDENT LIPID-PEROXIDATION AND VITAMIN-E CONTENT OF MICROSOMES FROM HEPATOMAS WITH DIFFERENT GROWTH-RATES	27	2
490	8	1062 1985 BIOCHEMISTRY 24(19):5115-5123 MARCUS CB; TURNER CR; JEFCOATE CR BINDING OF BENZO[A]PYRENE BY PURIFIED CYTOCHROME-P-450C	9	2
491	3	1085 1985 TOXICOLOGY AND APPLIED PHARMACOLOGY 77(2):315-324 MEREDITH CG; SPEEG KV; SCHENKER S NIZATIDINE, A NEW HISTAMINE H-2-RECEPTOR ANTAGONIST, AND HEPATIC OXIDATIVE DRUG-METABOLISM IN THE RAT - A COMPARISON WITH STRUCTURALLY RELATED-COMPOUNDS	17	2
492	7	1089 1985 VITAMINS AND HORMONES-ADVANCES IN RESEARCH AND APPLICATIONS 42():315-368 HALL PF ROLE OF CYTOCHROMES-P-450 IN THE BIOSYNTHESIS OF STEROID- HORMONES	41	2
493	4	1101 1986 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 246(1):19-32 WHITE RE; MCCARTHY MB ACTIVE-SITE MECHANICS OF LIVER MICROSOMAL CYTOCHROME-P-450	32	2
494	1	1120 1986 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 11(4):269-273 KOUROUNAKIS P; REKKA E EFFECT OF BENZOPYRONE DERIVATIVES ON DRUG ACTIVITY AND METABOLISM	3	2
495	2	1126 1986 JOURNAL OF BIOLOGICAL CHEMISTRY 261(8):3790-3799 KAWATA S; TRZASKOS JM; GAYLOR JL AFFINITY-CHROMATOGRAPHY OF MICROSOMAL-ENZYMES ON IMMOBILIZED DETERGENT-SOLUBILIZED CYTOCHROME-B5	17	2
496	1	1135 1986 TOXICOLOGY AND APPLIED PHARMACOLOGY 83(2):287-293 VILLARRUEL MC; FERNANDEZ G; DEFERREYRA EC; DEFENOS OM; CASTRO JA LATE PREVENTIVE EFFECTS OF TRIFLUOPERAZINE ON CARBON TETRACHLORIDE-INDUCED HEPATIC-NECROSIS	19	2
497	3	1138 1986 XENOBIOTICA 16(2):167-175 RUMYANTSEVA GV; SUSHKOV DG; WEINER LM MICROSOMAL OXIDATION OF 2-DIMETHYLAMINO-3-CHLORO-1,4- NAPHTHOQUINONE - THE POSSIBILITY OF SUBSTRATE ACTIVATION BY CYTOCHROME-P-450	6	2
498	2	1166 1987 MUTATION RESEARCH 180(1):11-20 ZIELENSKA M; GUTTENPLAN JB EFFECTS OF UV REPAIR, ERROR-PRONE REPAIR AND CRITICAL SITE OF MUTATION ON MUTAGENESIS INDUCED BY N-NITROSAMINES	13	2
499	2	1183 1988 BIOCHEMICAL PHARMACOLOGY 37(21):4157-4162 BANHEGYI G; GARZO T; ANTONI F; MANDL J ACCUMULATION OF PHENOLS AND CATECHOLS IN ISOLATED MOUSE HEPATOCYTES IN STARVATION OR AFTER PRETREATMENT WITH ACETONE	10	2
500	4	1219 1989 BIOCHEMICAL PHARMACOLOGY 38(8):1364-1368 MAYER RT; NETTER KJ; HEUBEL F; BUCHHEISTER A; BURKE MD FLUOROMETRIC ASSAY OF HEPATIC-MICROSOMAL MONOOXYGENASES BY USE OF 7-METHOXYQUINOLINE	5	2

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