#	Cited nodes	Nodes / Authors	GCS	LCS
1101	4	1101 1986 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 246(1):19-32 WHITE RE; MCCARTHY MB ACTIVE-SITE MECHANICS OF LIVER MICROSOMAL CYTOCHROME-P-450	32	2
1102	4	1102 1986 BIOCHEMICAL PHARMACOLOGY 35(8):1391-1394 PENG R; ZHU XY; YANG CS INDUCTION OF RAT-LIVER MICROSOMAL CYTOCHROME-P-450 BY MUSCONE (3-METHYLCYCLOPENTADECANONE)	4	0
1103	3	1103 1986 BIOCHEMICAL PHARMACOLOGY 35(11):1867-1878 LAVRIJSEN K; VANHOUDT J; THIJS D; MEULDERMANS W; HEYKANTS J INDUCTION POTENTIAL OF ANTIFUNGALS CONTAINING AN IMIDAZOLE OR TRIAZOLE MOIETY - MICONAZOLE AND KETOCONAZOLE, BUT NOT ITRACONAZOLE ARE ABLE TO INDUCE HEPATIC DRUG-METABOLIZING- ENZYMES OF MALE-RATS AT HIGH-DOSES	59	0
1104	13	1104 1986 BIOCHEMICAL PHARMACOLOGY 35(12):1971-1979 MURRAY M; LACEY E; FARRELL GC NEW HETEROCYCLIC MODIFIERS OF OXIDATIVE DRUG-METABOLISM .1. "6- SUBSTITUTED-2-AMINOBENZOTHIAZOLES	1	0
1105	7	1105 1986 BIOCHEMICAL PHARMACOLOGY 35(13):2149-2155 MURRAY M; FARRELL GC MECHANISTIC ASPECTS OF THE INHIBITION OF MICROSOMAL DRUG OXIDATION BY PRIMAQUINE	8	1
1106	8	1106 1986 BIOCHEMICAL PHARMACOLOGY 35(13):2157-2161 WINZOR DJ; IOANNONI B; REILLY PEB THE NATURE OF MICROSOMAL MONOOXYGENASE INHIBITION BY CIMETIDINE	19	4
1107	2	1107 1986 BIOCHEMICAL PHARMACOLOGY 35(15):2630-2632 WILLIAMS MT; SIMONET L EFFECTS OF GRISEOFULVIN ON ENZYMES ASSOCIATED WITH PHASE-I AND PHASE-II OF DRUG-METABOLISM	5	0
1108	2	1108 1986 BIOCHEMICAL PHARMACOLOGY 35(22):3941-3947 MASUDA Y; YASOSHIMA M; NAKAYAMA N EARLY, SELECTIVE AND REVERSIBLE SUPPRESSION OF CYTOCHROME P- 450-DEPENDENT MONOOXYGENASE OF LIVER-MICROSOMES FOLLOWING THE ADMINISTRATION OF LOW-DOSES OF CARBON-DISULFIDE IN MICE	13	1
1109	11	1109 1986 BIOCHEMICAL PHARMACOLOGY 35(24):4443-4448 BACKES WL; TURNER JL; HEIMANN TG; CANADY WJ ASSOCIATION OF HYDROPHOBIC SUBSTANCES WITH HEMIN - CHARACTERIZATION OF THE REVERSE TYPE-I BINDING SPECTRUM AND ITS RELATIONSHIP TO CYTOCHROME-P-450	5	3
1110	4	1110 1986 BIOCHEMISTRY 25(17):4804-4809 TAKAZAWA RS; STROBEL HW CYTOCHROME-P-450 MEDIATED REDUCTIVE DEHALOGENATION OF THE PERHALOGENATED AROMATIC COMPOUND HEXACHLOROBENZENE	9	0
1111	3	1111 1986 BIOCHIMICA ET BIOPHYSICA ACTA 876(2):220-225 MINOTTI G; BORRELLO S; PALOMBINI G; GALEOTTI T CYTOCHROME-P-450 DEFICIENCY AND RESISTANCE TO TRANS-BUTYL HYDROPEROXIDE OF HEPATOMA MICROSOMAL LIPID-PEROXIDATION	16	1
1112	2	1112 1986 CANCER RESEARCH 46(3):1224-1232 OCHS H; DUSTERBERG B; GUNZEL P; SCHULTEHERMANN R EFFECT OF TUMOR PROMOTING CONTRACEPTIVE STEROIDS ON GROWTH AND DRUG-METABOLIZING-ENZYMES IN RAT-LIVER	48	1
1113	2	1113 1986 CHEMICAL & PHARMACEUTICAL BULLETIN 34(10):4287-4293 IMAI K; AIMOTO T; SATO M; WATANABE K; KIMURA R; MURATA T EFFECTS OF SODIUM METALLOCHLOROPHYLLINS ON THE ACTIVITY AND COMPONENTS OF THE MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM IN RAT-LIVER	14	0
1114	9	1114 1986 CHEMICO-BIOLOGICAL INTERACTIONS 58(2):185-198 GIBSON GG; TAMBURINI PP CHEMICAL MODIFICATION OF THE HISTIDINE-RESIDUES OF PURIFIED HEPATIC CYTOCHROME-P-450 - INFLUENCE ON SUBSTRATE BINDING AND THE HEMOPROTEIN SPIN STATE	5	0
1115	5	1115 1986 CHEMICO-BIOLOGICAL INTERACTIONS 58(3):289-299 LEWIS DFV; TAMBURINI PP; GIBSON GG THE INTERACTION OF A HOMOLOGOUS SERIES OF HYDROCARBONS WITH HEPATIC CYTOCHROME-P-450 - MOLECULAR ORBITAL-DERIVED ELECTRONIC AND STRUCTURAL PARAMETERS INFLUENCING THE HEMOPROTEIN SPIN STATE	16	0
1116	4	1116 1986 CHEMICO-BIOLOGICAL INTERACTIONS 59(2):157-171 TESTAI E; VITTOZZI L BIOCHEMICAL-ALTERATIONS ELICITED IN RAT-LIVER MICROSOMES BY OXIDATION AND REDUCTION PRODUCTS OF CHLOROFORM METABOLISM	32	3
1117	3	1117 1986 CHEMICO-BIOLOGICAL INTERACTIONS 59(2):219-230 HEINE HS; STOSKOPF MK; THOMPSON DC; CHA YN ENHANCEMENT OF EPOXIDE HYDROLASE ACTIVITY IN HEPATIC MICROSOMES OF MICE GIVEN HETEROCYCLIC-COMPOUNDS	3	0
1118	29	1118 1986 CRC CRITICAL REVIEWS IN BIOCHEMISTRY 20(2):139-200 WEINER LM MAGNETIC-RESONANCE STUDY OF THE STRUCTURE AND FUNCTIONS OF CYTOCHROME-P450	21	3
1119	4	1119 1986 DRUG INTELLIGENCE & CLINICAL PHARMACY 20(5):342-348 NAZARIO M THE HEPATIC AND RENAL MECHANISMS OF DRUG-INTERACTIONS WITH CIMETIDINE	23	0
1120	1	1120 1986 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 11(4):269-273 KOUROUNAKIS P; REKKA E EFFECT OF BENZOPYRONE DERIVATIVES ON DRUG ACTIVITY AND METABOLISM	3	2
1121	5	1121 1986 FEBS LETTERS 209(2):305-310 BORRELLO S; GALEOTTI T; PALOMBINI G; MINOTTI G RESTORATION OF HYDROPEROXIDE-DEPENDENT LIPID-PEROXIDATION BY 3- METHYLCHOLANTHRENE INDUCTION OF CYTOCHROME-P-448 IN HEPATOMA MICROSOMES	1	0
1122	1	1122 1986 INDIAN JOURNAL OF MEDICAL RESEARCH 83():538-545 NYANDIEKA HS METABOLIC EFFECT OF AFLATOXIN-B1 ON THE ACTIVITY OF DRUG- METABOLIZING-ENZYMES AND PLASMA-LEVEL OF MARKER ENZYMES OF LIVER DISORDER IN RELATION TO NUTRITIONAL STRESS	0	0
1123	3	1123 1986 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 12(8):1383-1387 LEE FYF; WORKMAN P INTERACTION OF NITROIMIDAZOLE SENSITIZERS WITH DRUG- METABOLIZING ENZYMES-SPECTRAL AND KINETIC-STUDIES	6	0
1124	3	1124 1986 JAPANESE JOURNAL OF PHARMACOLOGY 41(3):363-371 OKUNO H; HAZAMA H; MURASE T; SHIOZAKI Y; SAMESHIMA Y DRUG-METABOLIZING ACTIVITY IN RATS WITH CHRONIC LIVER-INJURY INDUCED BY CARBON-TETRACHLORIDE - RELATIONSHIP WITH THE CONTENT OF HYDROXYPROLINE IN THE LIVER	3	0
1125	3	1125 1986 JOURNAL OF APPLIED TOXICOLOGY 6(6):413-418 FERNANDEZ G; VILLARRUEL MC; DEFERREYRA EC; DEFENOS OM; CASTRO JA IMIPRAMINE PREVENTION OF CARBON TETRACHLORIDE-INDUCED LIVER NECROSIS AT LATE STATES OF THE INTOXICATION PROCESS	9	1
1126	2	1126 1986 JOURNAL OF BIOLOGICAL CHEMISTRY 261(8):3790-3799 KAWATA S; TRZASKOS JM; GAYLOR JL AFFINITY-CHROMATOGRAPHY OF MICROSOMAL-ENZYMES ON IMMOBILIZED DETERGENT-SOLUBILIZED CYTOCHROME-B5	17	2
1127	3	1127 1986 JOURNAL OF BIOLOGICAL CHEMISTRY 261(35):6689-6697 SONG BJ; GELBOIN HV; PARK SS; YANG CS; GONZALEZ FJ COMPLEMENTARY-DNA AND PROTEIN SEQUENCES OF ETHANOL-INDUCIBLE RAT AND HUMAN CYTOCHROME-P-450S - TRANSCRIPTIONAL AND POSTTRANSCRIPTIONAL REGULATION OF THE RAT ENZYME	407	0
1128	1	1128 1986 JOURNAL OF NUTRITION 116(4):682-688 HASHMI RS; SIDDIQUI AM; KACHOLE MS; PAWAR SS ALTERATIONS IN HEPATIC-MICROSOMAL MIXED-FUNCTION OXIDASE SYSTEM DURING DIFFERENT LEVELS OF FOOD RESTRICTION IN ADULT MALE AND FEMALE RATS	21	1
1129	1	1129 1986 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 19(1):111-125 CLEMENT RP; ZWICKER GM; CHIN TY; FREUDENTHAL RI 1-(8-METHOXY-4,8-DIMETHYLNONYL)-4-(1-METHYLETHYL)BENZENE (MV- 678) - A REVERSIBLE INDUCER OF RAT HEPATIC-MICROSOMAL DRUG- METABOLISM	0	0
1130	4	1130 1986 MICROBIOLOGICAL REVIEWS 50(3):244-258 KAPPELI O CYTOCHROMES-P-450 OF YEASTS	53	0
1131	3	1131 1986 STEROIDS 48(1-2):85-92 BRESKVAR K THE PROPERTIES OF CYTOCHROME-P-450 INDUCED IN THE RAT SMALL- INTESTINE BY ESTRADIOL	3	0
1132	5	1132 1986 STEROIDS 48(3-4):133-196 HALL PF CYTOCHROMES-P-450 AND THE REGULATION OF STEROID-SYNTHESIS	11	0
1133	3	1133 1986 TOXICOLOGY 40(3):327-339 KNIGHTS KM; CASSIDY MR; DREW R BENOXAPROFEN INDUCED TOXICITY IN ISOLATED RAT HEPATOCYTES	5	0
1134	4	1134 1986 TOXICOLOGY AND APPLIED PHARMACOLOGY 82(2):272-280 PATHIRATNE A; PUYEAR RL; BRAMMER JD A COMPARATIVE-STUDY OF THE EFFECTS OF BENZENE, TOLUENE, AND XYLENES ON THEIR INVITRO METABOLISM AND DRUG-METABOLIZING- ENZYMES IN RAT-LIVER	43	0
1135	1	1135 1986 TOXICOLOGY AND APPLIED PHARMACOLOGY 83(2):287-293 VILLARRUEL MC; FERNANDEZ G; DEFERREYRA EC; DEFENOS OM; CASTRO JA LATE PREVENTIVE EFFECTS OF TRIFLUOPERAZINE ON CARBON TETRACHLORIDE-INDUCED HEPATIC-NECROSIS	19	2
1136	10	1136 1986 UKRAINSKII BIOKHIMICHESKII ZHURNAL 58(2):104-116 GOLOVENKO NY; GALKIN BN CYTOCHROME-P-450-DEPENDENT PATHWAY FOR OXIDATION OF ARACHIDONIC-ACID AND ITS METABOLITES	1	1
1137	2	1137 1986 VETERINARY RESEARCH COMMUNICATIONS 10(4):317-324 FARGETTON X; GALTIER P; DELATOUR P SULFOXIDATION OF ALBENDAZOLE BY A CYTOCHROME P450-INDEPENDENT MONOOXYGENASE FROM RAT-LIVER MICROSOMES	32	0
1138	3	1138 1986 XENOBIOTICA 16(2):167-175 RUMYANTSEVA GV; SUSHKOV DG; WEINER LM MICROSOMAL OXIDATION OF 2-DIMETHYLAMINO-3-CHLORO-1,4- NAPHTHOQUINONE - THE POSSIBILITY OF SUBSTRATE ACTIVATION BY CYTOCHROME-P-450	6	2
1139	1	1139 1987 ACS SYMPOSIUM SERIES 355():340-352 KATAGI T; MIKAMI N; MATSUDA T; MIYAMOTO J APPLICATION OF MOLECULAR-ORBITAL CALCULATIONS TO ESTIMATE THE ACTIVE CONFORMATION OF AZOLE COMPOUNDS	1	0
1140	17	1140 1987 ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY 60():35-87 BLACK SD; COON MJ P-450 CYTOCHROMES - STRUCTURE AND FUNCTION	162	3
1141	4	1141 1987 ARCHIVES OF TOXICOLOGY 60(1-3):1-4 GREIM H EXPOSURE, TOXIC EFFECTS, AND PREVENTION - CONTRIBUTIONS OF TOXICOLOGY TO RISK ASSESSMENT AND HEALTH REGULATION - LAUDATIO TO REMMER,HERBERT	0	0
1142	3	1142 1987 BIOCHEMICAL PHARMACOLOGY 36(6):823-829 PESONEN M; ANDERSSON T SUBCELLULAR-LOCALIZATION AND PROPERTIES OF CYTOCHROME-P-450 AND UDP GLUCURONOSYLTRANSFERASE IN THE RAINBOW-TROUT KIDNEY	24	0
1143	4	1143 1987 BIOCHEMICAL PHARMACOLOGY 36(6):897-906 KNIGHTS KM; GOURLAY GK; COUSINS MJ CHANGES IN RAT HEPATIC-MICROSOMAL MIXED-FUNCTION OXIDASE ACTIVITY FOLLOWING EXPOSURE TO HALOTHANE UNDER VARIOUS OXYGEN CONCENTRATIONS	7	0
1144	4	1144 1987 BIOCHEMICAL PHARMACOLOGY 36(8):1349-1355 LEE FYF; WORKMAN P; CHEESEMAN KH MISONIDAZOLE AND BENZNIDAZOLE INHIBIT HYDROXYLATION OF CCNU BY MOUSE-LIVER MICROSOMAL CYTOCHROME-P-450 INVITRO	4	0
1145	2	1145 1987 BIOCHEMICAL PHARMACOLOGY 36(10):1741-1747 BEDNAR MM; KRAEMER R; ABRAHAM NG; MULLANE KM ARACHIDONIC-ACID MONOOXYGENASE AND LIPOXYGENASE ACTIVITIES IN POLYMORPHONUCLEAR LEUKOCYTES	19	0
1146	2	1146 1987 BIOCHEMICAL PHARMACOLOGY 36(15):2481-2487 JAYYOSI Z; TOTIS M; SOUHAILI H; GOULONGINET C; LIVERTOUX MH; BATT AM; SIEST G INDUCTION OF HEPATIC CYTOCHROME-P-450C-DEPENDENT MONOOXYGENASE ACTIVITIES BY DANTROLENE IN RAT	5	0
1147	3	1147 1987 BIOCHEMICAL PHARMACOLOGY 36(18):2921-2926 RAUCY J; FERNANDES P; BLACK M; YANG SL; KOOP DR IDENTIFICATION OF A HUMAN-LIVER CYTOCHROME-P-450 EXHIBITING CATALYTIC AND IMMUNOCHEMICAL SIMILARITIES TO CYTOCHROME-P-450- 3A OF RABBIT LIVER	38	1
1148	4	1148 1987 BIOCHEMISTRY-MOSCOW 52(6):898-902 AKHEM AA; SLEPNEVA LM; POPOVA EM; LIS LG; LAKHVICH FA; KISELEV PA KINETICS OF THE OXIDATION OF 15-ALPHA-METHYL-8-AZA-16-OXAGONA- 1,3,5(10),13-TETRAEN-17-ONE BY CYTOCHROME-P-450 OF RAT-LIVER MICROSOMES	0	0
1149	4	1149 1987 BIOCHEMISTRY-MOSCOW 52(11):1638-1646 SUSHKOV DG; RUMYANTSEVA GV; VAINER LM REDUCTION OF THE SUBSTRATE AND ACTIVATION OF OXYGEN IN THE MICROSOMAL METABOLISM OF QUINONES	0	0
1150	1	1150 1987 CANCER RESEARCH 47(16):4271-4277 KENSLER TW; EGNER PA; DOLAN PM; GROOPMAN JD; ROEBUCK BD MECHANISM OF PROTECTION AGAINST AFLATOXIN TUMORIGENICITY IN RATS FED 5-(2-PYRAZINYL)-4-METHYL-1,2-DITHIOL-3-THIONE (OLTIPRAZ) AND RELATED 1,2-DITHIOL-3-THIONES AND 1,2-DITHIOL-3- ONES	184	1
1151	5	1151 1987 CARCINOGENESIS 8(7):881-887 ROSSI M; MARKOVITZ S; CALLAHAN T DEFINING THE ACTIVE-SITE OF CYTOCHROME-P-450 - THE CRYSTAL AND MOLECULAR-STRUCTURE OF AN INHIBITOR, SKF-525A	11	0
1152	4	1152 1987 CARCINOGENESIS 8(12):1775-1779 MALAVEILLE C; BRUN G; PARK SS; GELBOIN HV; BARTSCH H A MONOCLONAL-ANTIBODY AGAINST CYTOCHROME-P-450 ENHANCES MUTAGEN ACTIVATION OF N-NITROSODIMETHYLAMINE BY MOUSE-LIVER S9 - STUDIES ON THE MODE OF ACTION	9	0
1153	2	1153 1987 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 88(2):619-624 VERDINA A; DEANGELIS G; FUNARI E; TESTAI E; VITTOZZI L XENOBIOTIC-METABOLIZING ENZYME-SYSTEMS IN TEST FISH .2. THE ETHYLMORPHINE N-DEMETHYLASE ACTIVITY OF GUPPY (POECILIA- RETICULATA) LIVER	7	0
1154	5	1154 1987 DRUG METABOLISM AND DISPOSITION 15(4):571-578 RUSH WR; SMITH SA; MULVEY JH; GRAHAM DJM; CHAPLIN MD INHIBITION AND INDUCTION OF HEPATIC DRUG-METABOLISM IN RATS AND MICE BY NAFIMIDONE AND ITS MAJOR METABOLITE NAFIMIDONE ALCOHOL	9	0
1155	2	1155 1987 DRUG METABOLISM AND DISPOSITION 15(5):676-681 SHOAF SE; SCHWARK WS; GUARD CL; BABISH JG THE DEVELOPMENT OF HEPATIC DRUG-METABOLIZING ENZYME-ACTIVITY IN THE NEONATAL CALF AND ITS EFFECT ON DRUG DISPOSITION	20	1
1156	16	1156 1987 DRUG METABOLISM REVIEWS 18(1):55-81 MURRAY M MECHANISMS OF THE INHIBITION OF CYTOCHROME-P-450-MEDIATED DRUG OXIDATION BY THERAPEUTIC AGENTS	72	6
1157	3	1157 1987 DRUG-NUTRIENT INTERACTIONS 5(3):181-189 ANDREWS SL; EVERS WD EFFECT OF NICOTINAMIDE ON DRUG-METABOLIZING-ENZYMES IN THE NEONATAL RAT	0	0
1158	2	1158 1987 FARMAKOLOGIYA I TOKSIKOLOGIYA 50(5):60-64 GREK OR; SHARAPOV VI PREVENTION OF ISCHEMIC LESIONS OF THE LIVER MONOOXYGENASE SYSTEM BY LIDOCAINE AND ALPHA-TOCOPHEROL	0	0
1159	6	1159 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262(2):801-810 HARDWICK JP; SONG BJ; HUBERMAN E; GONZALEZ FJ ISOLATION, COMPLEMENTARY-DNA SEQUENCE, AND REGULATION OF RAT HEPATIC LAURIC ACID OMEGA-HYDROXYLASE (CYTOCHROME-P-450LA- OMEGA) - IDENTIFICATION OF A NEW CYTOCHROME-P-450 GENE FAMILY	304	1
1160	3	1160 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262(29):14319-14326 FAVREAU LV; MALCHOFF DM; MOLE JE; SCHENKMAN JB RESPONSES TO INSULIN BY 2 FORMS OF RAT HEPATIC-MICROSOMAL CYTOCHROME-P-450 THAT UNDERGO MAJOR (RLM6) AND MINOR (RLM5B) ELEVATIONS IN DIABETES	76	3
1161	1	1161 1987 JOURNAL OF PESTICIDE SCIENCE 12(4):627-633 KATAGI T; MIKAMI N; MATSUDA T; MIYAMOTO J STRUCTURAL STUDIES OF THE PLANT-GROWTH REGULATOR UNICONAZOLE (ES PURE) AND COMPUTER-AIDED ANALYSIS OF ITS INTERACTION WITH CYTOCHROME-P-450	4	0
1162	5	1162 1987 JOURNAL OF PHARMACOBIO-DYNAMICS 10(7):287-295 MORITA K; KONISHI H; ONO T; SHIMAKAWA H A COMPARISON OF THE INHIBITORY EFFECTS OF ROXATIDINE ACETATE HYDROCHLORIDE AND CIMETIDINE ON CYTOCHROME-P-450-MEDIATED DRUG- METABOLISM IN MOUSE HEPATIC MICROSOMES AND IN MAN INVIVO	14	4
1163	2	1163 1987 JOURNAL OF PHARMACY AND PHARMACOLOGY 39(2):84-89 SEAGO A; GORROD JW THE INVITRO METABOLISM OF [C-14] PENTOBARBITAL AND [C-14] PHENOBARBITONE BY HAMSTER LIVER-MICROSOMES	3	0
1164	1	1164 1987 LIFE SCIENCES 41(9):1141-1148 WILLIAMS MT; LEONARD D; SIMONET L EFFECTS OF PREGNENOLONE-16-ALPHA-CARBONITRILE ON DRUG- METABOLIZING-ENZYMES IN HYPOPHYSECTOMIZED FEMALE RATS	6	0
1165	4	1165 1987 MOLECULAR PHARMACOLOGY 31(1):117-121 MURRAY M; ZALUZNY L; DANNAN GA; GUENGERICH FP; FARRELL GC ALTERED REGULATION OF CYTOCHROME-P-450 ENZYMES IN CHOLINE- DEFICIENT CIRRHOTIC MALE-RAT LIVER - IMPAIRED REGULATION AND ACTIVITY OF THE MALE-SPECIFIC ANDROST-4-ENE-3,17-DIONE 16- ALPHA-HYDROXYLASE, CYTOCHROME-P-450UT-A, IN HEPATIC CIRRHOSIS	29	1
1166	2	1166 1987 MUTATION RESEARCH 180(1):11-20 ZIELENSKA M; GUTTENPLAN JB EFFECTS OF UV REPAIR, ERROR-PRONE REPAIR AND CRITICAL SITE OF MUTATION ON MUTAGENESIS INDUCED BY N-NITROSAMINES	13	2
1167	7	1167 1987 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 336(4):453-458 SCHULZ M; SCHMOLDT A INTERACTIONS OF THE HISTAMINE H-2-RECEPTOR ANTAGONIST ETINTIDINE WITH RAT-LIVER CYTOCHROME-P-450 - A COMPARISON WITH CIMETIDINE	3	0
1168	2	1168 1987 PHARMAZIE 42(10):677-680 HADJIPETROUKOUROUNAKIS L; YIANGOU M; KOUROUNAKIS P EFFECT OF AGE ON THE INDUCTION OF INVITRO DRUG-METABOLISM BY PREGNENOLONE-16-ALPHA-CARBONITRILE (PCN) - EFFECT OF AGE AND PCN ON IMMUNE-RESPONSES	1	0
1169	2	1169 1987 PLANTA MEDICA (2):135-140 CHOUDHURY BR; HAQUE SJ; PODDAR MK INVIVO AND INVITRO EFFECTS OF KALMEGH (ANDROGRAPHIS-PANICULATA) EXTRACT AND ANDROGRAPHOLIDE ON HEPATIC-MICROSOMAL DRUG- METABOLIZING-ENZYMES	2	0
1170	1	1170 1987 TOXICOLOGY AND APPLIED PHARMACOLOGY 89(1):19-28 MORGOTT DA; NOLAN RJ NONLINEAR KINETICS OF INHALED PROPYLENE-GLYCOL MONOMETHYL ETHER IN FISCHER 344 RATS FOLLOWING SINGLE AND REPEATED EXPOSURES	7	0
1171	4	1171 1987 XENOBIOTICA 17(1):1-9 VANDESTRAAT R; DEVRIES J; DEBOER HJR; VROMANS RM; VERMEULEN NPE RELATIONSHIP BETWEEN PARACETAMOL BINDING TO AND ITS OXIDATION BY 2 CYTOCHROMES-P-450 ISOZYMES - A PROTON NUCLEAR-MAGNETIC- RESONANCE AND SPECTROPHOTOMETRIC STUDY	27	3
1172	6	1172 1987 XENOBIOTICA 17(1):45-57 LAVRIJSEN K; VANHOUDT J; THIJS D; MEULDERMANS W; HEYKANTS J INTERACTION OF MICONAZOLE, KETOCONAZOLE AND ITRACONAZOLE WITH RAT-LIVER MICROSOMES	40	3
1173	3	1173 1987 XENOBIOTICA 17(2):223-228 BERNACCHI AS; DECASTRO CR; DETORANZO EGD; DEFERREYRA EC; DEFENOS OM; CASTRO JA EFFECTS OF CARBON-TETRACHLORIDE ON THE LIVER OF CHICKENS - EARLY BIOCHEMICAL AND ULTRASTRUCTURAL ALTERATIONS IN THE ABSENCE OF DETECTABLE LIPID-PEROXIDATION	6	0
1174	7	1174 1987 XENOBIOTICA 17(7):793-805 KAO LR; WILKINSON CF INHIBITION OF CYTOCHROME-P-450C-MEDIATED BENZO[A]PYRENE HYDROXYLASE AND ETHOXYRESORUFIN O-DEETHYLASE BY DIHYDROSAFROLE	5	0
1175	2	1175 1987 XENOBIOTICA 17(9):1095-1102 MACLEOD JN; SORENSEN MP; SHAPIRO BH STRAIN INDEPENDENT ELEVATION OF HEPATIC MONOOXYGENASE ENZYMES IN FEMALE MICE	20	0
1176	1	1176 1988 BIOCHEMICAL PHARMACOLOGY 37(5):849-854 BANHEGYI G; GARZO T; MESZAROS G; FARAGO A; ANTONI F; MANDL J CYCLIC AMP-DEPENDENT PHOSPHORYLATION IN THE CONTROL OF BIOTRANSFORMATION IN THE LIVER	17	1
1177	1	1177 1988 BIOCHEMICAL PHARMACOLOGY 37(10):1947-1953 FABRE G; CREVATPISANO P; DRAGNA S; COVO J; BARRA Y; CANO JP INVOLVEMENT OF THE MACROLIDE ANTIBIOTIC INDUCIBLE CYTOCHROME-P- 450 LM3C IN THE METABOLISM OF MIDAZOLAM BY MICROSOMAL FRACTIONS PREPARED FROM RABBIT LIVER	41	1
1178	2	1178 1988 BIOCHEMICAL PHARMACOLOGY 37(10):1971-1979 BEYELER S; TESTA B; PERRISSOUD D FLAVONOIDS AS INHIBITORS OF RAT-LIVER MONOOXYGENASE ACTIVITIES	45	0
1179	1	1179 1988 BIOCHEMICAL PHARMACOLOGY 37(15):3049-3053 WANG RW; MIWA GT; ARGENBRIGHT LS; LU AYH INVITRO STUDIES ON THE INTERACTION OF FAMOTIDINE WITH LIVER MICROSOMAL CYTOCHROME-P-450	7	0
1180	4	1180 1988 BIOCHEMICAL PHARMACOLOGY 37(18):3505-3509 FAVREAU LV; SCHENKMAN JB CYTOCHROME-P-450 ALTERATIONS IN THE BB/WOR SPONTANEOUSLY DIABETIC RAT	10	1
1181	1	1181 1988 BIOCHEMICAL PHARMACOLOGY 37(19):3709-3715 NEMERY B; ALDRIDGE WN STUDIES ON THE METABOLISM OF THE PNEUMOTOXIN O,S,S-TRIMETHYL PHOSPHORODITHIOATE .1. LUNG AND LIVER-MICROSOMES	8	0
1182	1	1182 1988 BIOCHEMICAL PHARMACOLOGY 37(19):3781-3785 COJOCEL C; KRAMER W; MAYER D DEPLETION OF CYTOCHROME-P-450 AND ALTERATIONS IN ACTIVITIES OF DRUG-METABOLIZING ENZYMES INDUCED BY CEPHALORIDINE IN THE RAT- KIDNEY CORTEX	5	0
1183	2	1183 1988 BIOCHEMICAL PHARMACOLOGY 37(21):4157-4162 BANHEGYI G; GARZO T; ANTONI F; MANDL J ACCUMULATION OF PHENOLS AND CATECHOLS IN ISOLATED MOUSE HEPATOCYTES IN STARVATION OR AFTER PRETREATMENT WITH ACETONE	10	2
1184	7	1184 1988 BIOCHEMISTRY 27(4):1147-1153 NARASIMHULU S QUENCHING OF TRYPTOPHANYL FLUORESCENCE OF BOVINE ADRENAL P- 450C-21 AND INHIBITION OF SUBSTRATE BINDING BY ACRYLAMIDE	10	1
1185	4	1185 1988 CANCER RESEARCH 48(9):2462-2468 SCHULTEHERMANN R; OCHS H; BURSCH W; PARZEFALL W QUANTITATIVE STRUCTURE-ACTIVITY STUDIES ON EFFECTS OF 16 DIFFERENT STEROIDS ON GROWTH AND MONOOXYGENASES OF RAT-LIVER	42	0
1186	3	1186 1988 COORDINATION CHEMISTRY REVIEWS 86():245-271 BACCI M STATIC AND DYNAMIC EFFECTS IN SPIN EQUILIBRIUM SYSTEMS	40	0
1187	2	1187 1988 DRUG AND CHEMICAL TOXICOLOGY 11(4):387-403 FIORUCCI L; MONTI A; TESTAI E; ADE P; VITTOZZI L INVITRO EFFECTS OF POLYHALOGENATED HYDROCARBONS ON LIVER- MITOCHONDRIA RESPIRATION AND MICROSOMAL CYTOCHROME-P-450	3	0
1188	4	1188 1988 DRUG METABOLISM AND DISPOSITION 16(1):9-14 LESHER GA; BEIERSCHMITT WP L-ALPHA-ACETYLMETHADOL ADMINISTRATION TO LACTATING RAT DAMS - EFFECT ON HEPATIC ANILINE HYDROXYLASE AND ETHYLMORPHINE N- DEMETHYLASE ACTIVITIES IN RAT PUPS	0	0
1189	3	1189 1988 DRUG METABOLISM AND DISPOSITION 16(1):156-161 NARIMATSU S; MATSUBARA K; SHIMONISHI T; WATANABE K; YAMAMOTO I; YOSHIMURA H ENZYMATIC OXIDATION OF 7-HYDROXYLATED DELTA-8- TETRAHYDROCANNABINOL TO 7-OXO-DELTA-8-TETRAHYDROCANNABINOL BY HEPATIC MICROSOMES OF THE GUINEA-PIG	11	0
1190	1	1190 1988 DRUG METABOLISM AND DISPOSITION 16(4):557-562 SABOURIN PJ; TYNES RE; PHILPOT RM; WINQUIST S; DAHL AR DISTRIBUTION OF MICROSOMAL MONOOXYGENASES IN THE RABBIT RESPIRATORY-TRACT	31	1
1191	3	1191 1988 DRUG METABOLISM AND DISPOSITION 16(6):823-828 KYEREMATEN GA; OWENS GF; CHATTOPADHYAY B; DEBETHIZY JD; VESELL ES SEXUAL DIMORPHISM OF NICOTINE METABOLISM AND DISTRIBUTION IN THE RAT - STUDIES INVIVO AND INVITRO	33	0
1192	1	1192 1988 EKSPERIMENTALNAYA ONKOLOGIYA 10(5):52-55 OBLAPENKO NG; PRIHODKO AZ; FONSTEIN LM; CHERNOV VA STUDIES ON THE BIOTRANSFORMATION PROCESSES OF CERTAIN ANTITUMOUR DRUGS BY MEANS OF THE AMES TEST	0	0
1193	5	1193 1988 EUROPEAN JOURNAL OF BIOCHEMISTRY 172(2):315-324 SUMIMOTO H; TAKESHIGE K; MINAKAMI S CHARACTERIZATION OF HUMAN NEUTROPHIL LEUKOTRIENE-B4 OMEGA- HYDROXYLASE AS A SYSTEM INVOLVING A UNIQUE CYTOCHROME-P-450 AND NADPH CYTOCHROME-P-450 REDUCTASE	48	1
1194	1	1194 1988 INDIAN JOURNAL OF MEDICAL RESEARCH 88():51-56 DATTA UK; MAITY CR HEPATIC FUNCTIONS OF ALBINO-RATS DURING LACTATION	1	0
1195	3	1195 1988 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 36(2):344-349 KATAGI T STRUCTURAL STUDIES OF THE VINYLTRIAZOLE FUNGICIDE DINICONAZOLE (ER PURE) RELATED TO ITS BINDING TO CYTOCHROME-P-450	5	0
1196	1	1196 1988 JOURNAL OF APPLIED TOXICOLOGY 8(3):201-209 SCHLEGELMILCH R; KRUG A; WOLF HU MUTAGENIC ACTIVITY OF ACETONITRILE AND FUMARONITRILE IN 3 SHORT-TERM ASSAYS WITH SPECIAL REFERENCE TO AUTOINDUCTION	2	0
1197	3	1197 1988 JOURNAL OF BIOCHEMICAL TOXICOLOGY 3():131-145 DUTTON DR; MCMILLEN SK; PARKINSON A PURIFICATION OF RAT-LIVER MICROSOMAL CYTOCHROME-P-450B WITHOUT THE USE OF NONIONIC DETERGENT	13	1
1198	2	1198 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(33):17672-17677 JOHNSON EF; SCHWAB GE; VICKERY LE POSITIVE EFFECTORS OF THE BINDING OF AN ACTIVE SITE-DIRECTED AMINO STEROID TO RABBIT CYTOCHROME-P-450-3C	50	5
1199	6	1199 1988 JOURNAL OF PHARMACOBIO-DYNAMICS 11(2):106-114 MORITA K; ONO T; SHIMAKAWA H INHIBITORY EFFECTS OF KETOCONAZOLE AND MICONAZOLE ON CYTOCHROME-P-450-MEDIATED OXIDATIVE-METABOLISM OF TESTOSTERONE AND XENOBIOTICS IN MOUSE HEPATIC MICROSOMES - COMPARATIVE-STUDY WITH CIMETIDINE	18	4
1200	6	1200 1988 JOURNAL OF PHARMACOBIO-DYNAMICS 11(7):519-525 MORITA K; ONO T; SHIMAKAWA H EFFECTS OF OZAGREL (OKY-046), A THROMBOXANE SYNTHASE INHIBITOR, ON OXIDATIVE DRUG-METABOLIZING-ENZYMES IN MOUSE HEPATIC MICROSOMES	5	1

#	Cited nodes	Nodes / Authors	GCS	LCS
1201	3	1201 1988 JOURNAL OF PHARMACY AND PHARMACOLOGY 40(1):17-21 SALMONA M; CONTI I; TESTA R; FRACASSO C; CACCIA S INTERACTION OF THE ANTICONVULSANTS, DENZIMOL AND NAFIMIDONE, WITH LIVER CYTOCHROME-P450 IN THE RAT	4	0
1202	2	1202 1988 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 23(2):183-192 MARTINO PE; GOMEZ MID; TAMAYO D; LOPEZ AJ; CASTRO JA STUDIES ON THE MECHANISM OF THE ACUTE AND CARCINOGENIC EFFECTS OF N-NITROSODIMETHYLAMINE ON MINK LIVER	7	0
1203	1	1203 1988 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 24(2):217-227 RIDLEY WP; WARREN J; NAIR RS EFFECT OF TETRACHLOROPHTHALIC ANHYDRIDE ON HEPATIC-MICROSOMAL METABOLISM IN RATS AND MICE	0	0
1204	2	1204 1988 MOLECULAR BIOLOGY 22(4):800-804 SLYNKO NM; LEONOVA IN; PAK EV; SLEPNEVA IA; WEINER LM STUDY OF ACTIVE-SITE STRUCTURE OF MEMBRANE-BOUND CYTOCHROME- P450 USING 1-NAPHTHOXYALKANTHIOLS	1	0
1205	2	1205 1988 MUTATION RESEARCH 202(1):269-276 ZIELENSKA M; GUTTENPLAN JB MUTAGENIC ACTIVITY AND SPECIFICITY OF N-NITROSOMETHYLANILINE AND N-NITROSODIPHENYLAMINE IN SALMONELLA	16	1
1206	4	1206 1988 TOXICOLOGY AND APPLIED PHARMACOLOGY 94(1):1-10 ERICKSON DA; GOODRICH MS; LECH JJ THE EFFECT OF PIPERONYL BUTOXIDE ON HEPATIC CYTOCHROME-P-450- DEPENDENT MONOOXYGENASE ACTIVITIES IN RAINBOW-TROUT (SALMO- GAIRDNERI)	21	0
1207	3	1207 1988 TOXICOLOGY LETTERS 42(2):109-115 GOVINDWAR SP; KACHOLE MS; PAWAR SS EFFECT OF CAFFEINE ON THE HEPATIC-MICROSOMAL MIXED-FUNCTION OXIDASE SYSTEM DURING PHENOBARBITAL AND BENZO(A)PYRENE TREATMENT IN RATS	2	1
1208	1	1208 1988 VESTNIK AKADEMII MEDITSINSKIKH NAUK SSSR (1):24-33 ADRIANOV NV; UVAROV VY REGULATION OF ENZYME-SYSTEMS THAT OXIDIZE FOREIGN COMPOUNDS	0	0
1209	3	1209 1988 XENOBIOTICA 18(5):485-490 ZYCHLINSKI L; RASKAEMERY P; MONTGOMERY MR ARTIFACTS IN THE DETERMINATION OF MICROSOMAL XENOBIOTIC N- DEMETHYLATION IN THE PRESENCE OF ASCORBIC-ACID TRIS BUFFER AND NASH REAGENT	2	0
1210	5	1210 1988 XENOBIOTICA 18(7):785-796 TWEEDIE DJ; PROUGH RA; BURKE MD EFFECTS OF INDUCTION ON THE METABOLISM AND CYTOCHROME-P-450 BINDING OF HARMAN AND OTHER BETA-CARBOLINES	4	0
1211	7	1211 1988 XENOBIOTICA 18(9):1005-1014 GELDERBLOM WCA; SWART P; KRAMER PS INVESTIGATIONS ON THE SPECTRAL INTERACTIONS OF FUSARIN-C WITH RAT-LIVER MICROSOMAL CYTOCHROME-P-450	0	0
1212	3	1212 1988 XENOBIOTICA 18(9):1039-1048 KUREBAYASHI H; TANAKA A; YAMAHA T; TATAHASHI A OXIDATIVE DEAMINATION OF ALICYCLIC PRIMARY AMINES BY LIVER- MICROSOMES FROM RATS AND RABBITS	0	0
1213	3	1213 1988 XENOBIOTICA 18(10):1109-1118 HODEK P; JANSCAK P; ANZENBACHER P; BURKHARD J; JANKU J; VODICKA L METABOLISM OF DIAMANTANE BY RAT-LIVER MICROSOMAL CYTOCHROMES-P- 450	21	3
1214	1	1214 1988 XENOBIOTICA 18(12):1457-1464 TAKANO T; MIYAZAKI Y; ARAKI R INTERACTION OF 1,1,1-TRICHLOROETHANE WITH THE MIXED-FUNCTION OXIDATION SYSTEM IN RAT-LIVER MICROSOMES	6	1
1215	2	1215 1988 ZEITSCHRIFT FUR GASTROENTEROLOGIE 26(3):188-190 SEITZ HK; SIMANOWSKI UA; SIMON B; KOMMERELL B EFFECT OF OMEPRAZOLE ON ETHANOL OXIDATION AND ANILINE HYDROXYLATION IN RAT HEPATIC MICROSOMES	5	0
1216	1	1216 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 269(1):264-271 NAGI MN; LAGUNA JC; COOK L; CINTI DL DISRUPTION OF RAT HEPATIC-MICROSOMAL ELECTRON-TRANSPORT CHAINS BY THE SELENIUM-CONTAINING ANTI-INFLAMMATORY AGENT EBSELEN	18	0
1217	2	1217 1989 ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH 39-2(11):1399-1402 TANI E; REKKA E; ICONOMIDIS G; KOUROUNAKIS PN MODIFICATION OF DRUG METABOLIC PROCESSES BY COMPOUNDS WHICH INTERVENE WITH THE FUNCTION OF CYTOCHROME-P-450 AS A MONO- OXYGENASE AND AS AN OXIDASE	8	0
1218	3	1218 1989 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 158(2):480-484 FRIEDMAN FK; ROBINSON RC; RIFKIND J AGE-RELATED-CHANGES IN THE IRON SPIN STATE OF TESTOSTERONE- BINDING RAT-LIVER MICROSOMAL CYTOCHROMES-P-450	1	0
1219	4	1219 1989 BIOCHEMICAL PHARMACOLOGY 38(8):1364-1368 MAYER RT; NETTER KJ; HEUBEL F; BUCHHEISTER A; BURKE MD FLUOROMETRIC ASSAY OF HEPATIC-MICROSOMAL MONOOXYGENASES BY USE OF 7-METHOXYQUINOLINE	5	2
1220	4	1220 1989 BIOCHEMICAL PHARMACOLOGY 38(16):2639-2644 MORRIS CQ; TUCKER GT; CREWE HK; HARLOW JR; WOODS HF; LENNARD MS HISTAMINE INHIBITION OF MIXED-FUNCTION OXIDASE ACTIVITY IN RAT AND HUMAN-LIVER MICROSOMES AND IN THE ISOLATED PERFUSED RAT- LIVER	6	0
1221	6	1221 1989 BIOCHEMICAL PHARMACOLOGY 38(18):3037-3043 HLAVICA P; KUNZEL U; ACHTERT G SOME PROPERTIES OF AN INHIBITORY CYTOCHROME-P-450 METABOLIC- INTERMEDIATE COMPLEX EXISTING IN A SPIN-STATE EQUILIBRIUM	1	0
1222	1	1222 1989 BIOCHEMICAL PHARMACOLOGY 38(22):3913-3923 CHAPMAN DE; HOLBROOK DJ; CHANEY SG; HALL IH; LEE KH INVITRO INHIBITION OF MOUSE HEPATIC MIXED-FUNCTION OXIDASE ENZYMES BY HELENALIN AND ALANTOLACTONE	8	1
1223	5	1223 1989 BIOCHEMICAL PHARMACOLOGY 38(23):4217-4223 WOLFF T; WANDERS H; GUENGERICH FP ORGANIC-SOLVENTS AS MODIFIERS OF ALDRIN EPOXIDASE IN RECONSTITUTED MONOOXYGENASE SYSTEMS AND IN MICROSOMES	5	0
1224	1	1224 1989 BIOCHEMISTRY-MOSCOW 54(4):536-541 DOVGII AI; ADRIANOV NV INVESTIGATION OF THE TURNOVER RATE OF MOUSE-LIVER MICROSOME PROTEINS	0	0
1225	4	1225 1989 BIOORGANICHESKAYA KHIMIYA 15(8):1044-1055 WOLDMAN YY; GULYAEVA LF; WEINER LM; LYAKHOVICH VV INTERACTION OF CYTOCHROME-P-450 WITH SUBSTRATES BY MEANS OF UV AND H-1-NMR SPECTRA	1	1
1226	2	1226 1989 CANCER LETTERS 47(3):211-216 RICHER N; MARION M; DENIZEAU F INHIBITION OF BINDING OF 2-ACETYLAMINOFLUORENE TO DNA BY BUTYLATED HYDROXYTOLUENE AND BUTYLATED HYDROXYANISOLE INVITRO	3	0
1227	6	1227 1989 CHEMICAL & PHARMACEUTICAL BULLETIN 37(12):3351-3354 MORITA K; YAMAKAWA M; MINOUCHI T; HAYASHI Y; HOSHINO N; KONISHI H; ONO T; SHIMAKAWA H OZAGREL HYDROCHLORIDE MONOHYDRATE, A THROMBOXANE SYNTHASE INHIBITOR, AND ITS METABOLITES AS INHIBITORS OF HEPATIC- MICROSOMAL DRUG-METABOLISM	2	1
1228	4	1228 1989 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 92(2):329-339 JEWELL CSE; WINSTON GW CHARACTERIZATION OF THE MICROSOMAL MIXED-FUNCTION OXYGENASE SYSTEM OF THE HEPATOPANCREAS AND GREEN GLAND OF THE RED SWAMP CRAYFISH, PROCAMBARUS-CLARKII	25	1
1229	7	1229 1989 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 92(1):109-115 ISCAN MY; BUYUKBINGOL E; ISCAN M; SAHIN F; SAFAK C EFFECTS OF 2-ARYLBENZIMIDAZOLES ON RAT HEPATIC-MICROSOMAL MONOOXYGENASE SYSTEM	5	0
1230	3	1230 1989 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 93(2):355-357 MORENO JJ; CASTELLOTE MC; QUERALT J EFFECTS INVITRO OF COPPER AND ZINC ON HEPATIC CYTOCHROME-P-450 ACTIVITIES	6	0
1231	7	1231 1989 EXPERIMENTAL AND MOLECULAR PATHOLOGY 50(2):253-269 DEFERREYRA EC; VILLARRUEL MC; FERNANDEZ G; DEFENOS OM; BERNACCHI AS; DECASTRO CR; CASTRO JA FURTHER-STUDIES ON THE MECHANISM OF THE LATE PROTECTIVE EFFECTS OF PHENYLMETHYLSULFONYL FLUORIDE ON CARBON TETRACHLORIDE- INDUCED LIVER NECROSIS	4	0
1232	2	1232 1989 GASTROENTEROLOGY 97(2):446-456 SEITZ HK; MEYDANI M; FERSCHKE I; SIMANOWSKI UA; BOESCHE J; BOGUSZ M; HOEPKER WW; BLUMBERG JB; RUSSELL RM EFFECT OF AGING ON INVIVO AND INVITRO ETHANOL-METABOLISM AND ITS TOXICITY IN F344-RATS	13	0
1233	2	1233 1989 JAPANESE JOURNAL OF PHARMACOLOGY 49(2):285-291 MOOCHHALA SM; LEE EJD; HU GTM; KOH OS; BECKET G EFFECTS OF BROMOCRIPTINE ON HEPATIC CYTOCHROME-P-450 MONOOXYGENASE SYSTEM	1	0
1234	2	1234 1989 JOURNAL OF MEDICINAL CHEMISTRY 32(10):2231-2239 VANWAUWE JP; JANSSEN PAJ IS THERE A CASE FOR P-450 INHIBITORS IN CANCER-TREATMENT	79	0
1235	7	1235 1989 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 33(1):33-39 KUHNVELTEN N; MEYER I; STAIB W SPECIFICITY OF STEROID BINDING TO TESTICULAR MICROSOMAL CYTOCHROME-P-450 - RELATION OF STEROID STRUCTURE TO TYPE-I SPECTRAL RESPONSES AFTER CORRECTION FOR HYDROPHOBIC ASSOCIATION WITH THE MEMBRANE	12	3
1236	1	1236 1989 MARINE ENVIRONMENTAL RESEARCH 27(1):51-65 WATANABE S; SHIMADA T; NAKAMURA S; NISHIYAMA N; YAMASHITA N; TANABE S; TATSUKAWA R SPECIFIC PROFILE OF LIVER MICROSOMAL CYTOCHROME-P-450 IN DOLPHIN AND WHALES	67	0
1237	5	1237 1989 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 35(2):107-118 JOHNSTON G; COLLETT G; WALKER C; DAWSON A; BOYD I; OSBORN D ENHANCEMENT OF MALATHION TOXICITY TO THE HYBRID RED-LEGGED PARTRIDGE FOLLOWING EXPOSURE TO PROCHLORAZ	24	0
1238	5	1238 1989 PHARMACOLOGICAL RESEARCH 21(5):549-560 FACINO RM; CARINI M; GENCHI C; TOFANETTI O; CASCIARRI I PARTICIPATION OF LIPID-PEROXIDATION IN THE LOSS OF HEPATIC DRUG-METABOLIZING ACTIVITIES IN EXPERIMENTAL FASCIOLIASIS IN THE RAT	14	1
1239	1	1239 1989 PHARMACOLOGY 38(2):129-136 BUCHHOLZ J; STROTHER A; FRASER IM EFFECT OF GLUCOSE-ADMINISTRATION ON VARIOUS RAT HEPATIC CONSTITUENTS AND ON THE SPECTRAL BINDING OF HEXOBARBITAL AND METHADONE TO RAT HEPATIC CYTOCHROME P450	8	0
1240	3	1240 1989 XENOBIOTICA 19(3):255-267 SNEGAROFF J; BACH J EFFECTS OF THE FUNGICIDE PROCHLORAZ ON XENOBIOTIC METABOLISM IN RAINBOW-TROUT - INHIBITION INVITRO AND TIME COURSE OF INDUCTION INVIVO	17	0
1241	5	1241 1989 XENOBIOTICA 19(10):1181-1200 JEWELL CSE; CUMMINGS LE; RONIS MJJ; WINSTON GW THE HEPATIC-MICROSOMAL MIXED-FUNCTION OXYGENASE (MFO) SYSTEM OF ALLIGATOR-MISSISSIPPIENSIS - INDUCTION BY 3-METHYLCHOLANTHRENE (MC)	25	0
1242	1	1242 1989 XENOBIOTICA 19(11):1319-1326 HAHNEMANN B; LEGRUM W; KOSS G; NETTER KJ INTERACTIONS OF HETEROCYCLIC MAILLARD PRODUCTS WITH THE HEPATIC-MICROSOMAL MONOOXYGENASE SYSTEM	0	0
1243	2	1243 1990 ADVANCES IN PROSTAGLANDIN THROMBOXANE AND LEUKOTRIENE RESEARCH 20():95-101 ULLRICH V; HECKER M A CONCEPT FOR THE MECHANISM OF PROSTACYCLIN AND THROMBOXANE-A2 BIOSYNTHESIS	7	0
1244	5	1244 1990 ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH 40-1(4):490-498 FACINO RM; CARINI M; GENCHI C; TOFANETTI O; CASCIARRI I; BEDOSCHI D ANTIHEPATOTOXIC PROPERTIES OF URIDINE-DIPHOSPHOGLUCOSE IN LIVER FLUKE INFECTION - EXPERIMENTAL FASCIOLIASIS IN THE RAT	5	0
1245	1	1245 1990 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 167(3):1271-1278 CHASSEROTGOLAZ S; RIBEIRO V; GENOT G; LECHNER MC; BECK G THE STEROID ANTAGONIST RU38486 IS METABOLIZED BY THE LIVER MICROSOMAL-P450 MONO-OXYGENASES	9	0
1246	1	1246 1990 BIOCHEMICAL PHARMACOLOGY 39(1):229-230 HALLIDAY SE; SKETT P INTERFERENCE BY META-VANADATE IN THE ASSAY FOR FORMALDEHYDE AND 4-AMINOPHENOL	5	0
1247	6	1247 1990 BIOCHEMICAL PHARMACOLOGY 40(7):1645-1655 MAYER RT; NETTER KJ; HEUBEL F; HAHNEMANN B; BUCHHEISTER A; MAYER GK; BURKE MD 7-ALKOXYQUINOLINES - NEW FLUORESCENT SUBSTRATES FOR CYTOCHROME- P450 MONOOXYGENASES	28	2
1248	1	1248 1990 BIOCHEMISTRY INTERNATIONAL 22(5):895-902 SHAHI GS; MOOCHHALA SM; DAS NP; SUNAMOTO J; TAJIMA K THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) INDUCES CHANGES IN THE HEME SPIN STATE OF MICROSOMAL CYTOCHROME-P-450	2	0
1249	2	1249 1990 BIOCHIMICA ET BIOPHYSICA ACTA 1038(1):130-135 LANGE R; PERIN F; LARROQUE C; ZAJDELA F ISOLATION AND PARTIAL CHARACTERIZATION OF A CYTOCHROME-P-450 ISOENZYME (CYTOCHROME-P-450TU) FROM MOUSE-LIVER TUMORS	21	0
1250	1	1250 1990 BIOLOGY OF THE NEONATE 57(6):367-374 OSUIDE G; WAMBEBE C; IKEDIOBI CO; KWANASHIE HO DOSE-RELATED AND OTHER EFFECTS OF MATERNAL CIMETIDINE PRETREATMENT DURING LACTATION ON DRUG-METABOLISM IN MOUSE DAMS AND PUPS	1	0
1251	1	1251 1990 BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE 109(6):724-727 KHUDOLEI VV; MIZGIREV IV; MAIOROVA IG ENZYMATIC IMPRINTING IN ADULT ANIMALS	0	0
1252	7	1252 1990 CANCER CHEMOTHERAPY AND PHARMACOLOGY 25(4):227-235 STOLZENBACH JC; LARSON RE BCNU-INDUCED QUANTITATIVE AND QUALITATIVE CHANGES IN HEPATIC CYTOCHROME-P-450 CAN BE CORRELATED WITH CHOLESTASIS	4	0
1253	1	1253 1990 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 96(1):217-222 GAULE C; VEGA P; SANCHEZ E; DELVILLAR E DRUG-METABOLISM IN OCTODON-DEGUS - LOW INDUCTIVE EFFECT OF PHENOBARBITAL	1	0
1254	2	1254 1990 ENDOCRINOLOGY 126(6):3101-3106 AOYAMA T; KORZEKWA K; NAGATA K; GILLETTE J; GELBOIN HV; GONZALEZ FJ ESTRADIOL METABOLISM BY COMPLEMENTARY DEOXYRIBONUCLEIC ACID- EXPRESSED HUMAN CYTOCHROME-P450S	107	1
1255	5	1255 1990 EUROPEAN JOURNAL OF BIOCHEMISTRY 188(1):187-194 BONFILS C; COMBALBERT J; PINEAU T; ANGEVIN J; LARROQUE C; DERANCOURT J; CAPONY JP; MAUREL P ONTOGENY OF RABBIT LIVER CYTOCHROME-P450 - EVIDENCE FOR A CYTOCHROME-P450-IIE (3A)-RELATED FORM PREVAILING DURING THE POSTNATAL-PERIOD	24	0
1256	1	1256 1990 EUROPEAN JOURNAL OF BIOCHEMISTRY 194(3):889-896 RENAUD JP; CULLIN C; POMPON D; BEAUNE P; MANSUY D EXPRESSION OF HUMAN LIVER CYTOCHROME-P450 IIIA4 IN YEAST - A FUNCTIONAL-MODEL FOR THE HEPATIC ENZYME	79	2
1257	1	1257 1990 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 25(8):701-704 KOUROUNAKIS PN; REKKA E STRUCTURAL CONSIDERATIONS OF THE 16-CYANO AND RELATED PREGNENOLONES ON THEIR DRUG METABOLIC INDUCING ACTIVITY	2	1
1258	4	1258 1990 EXPERIMENTAL AND MOLECULAR PATHOLOGY 52(3):330-339 TEKWANI BL; TRIPATHI LM; MUKERJEE S; GUPTA S; PANDEY VC; KATIYAR JC; GHATAK S; SHUKLA OP HEPATIC-MICROSOMAL CYTOCHROME-P450 SYSTEM DURING EXPERIMENTAL HOOKWORM INFECTION	2	0
1259	2	1259 1990 EXPERIMENTAL PATHOLOGY 39(3-4):187-194 MULLER D INFLUENCE OF XENOBIOTICS ON DRUG-METABOLISM AND ITS SENSITIVE DETECTION	13	2
1260	1	1260 1990 FEBS LETTERS 270(1-2):177-180 MYASOEDOVA KN; BERNDT P IMMOBILIZED CYTOCHROME-P-450LM2 - DISSOCIATION AND REASSOCIATION OF OLIGOMERS	9	0
1261	1	1261 1990 INDIAN JOURNAL OF MEDICAL RESEARCH SECTION B-BIOMEDICAL RESEARCH OTHER THAN INFECTIOUS DISEASES 92():332-336 NYANDIEKA HS; WAKHIS J; KILONZO MM ASSOCIATION OF REDUCTION OF AFB1-INDUCED LIVER-TUMORS BY ANTIOXIDANTS WITH INCREASED ACTIVITY OF MICROSOMAL-ENZYMES	5	0
1262	1	1262 1990 INDIAN JOURNAL OF MEDICAL RESEARCH SECTION B-BIOMEDICAL RESEARCH OTHER THAN INFECTIOUS DISEASES 92():374-377 BHATTACHARYYA A; SAHU JK; MAJUMDAR G; MAITY CR BIOCHEMICAL-STUDIES OF LIVER AND LIVER-MICROSOMES IN ENVENOMATED RATS	0	0
1263	2	1263 1990 JOURNAL OF PHARMACY AND PHARMACOLOGY 42(1):58-59 DALVI RR; TERSE PS INDUCTION OF HEPATIC-MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM BY LEVAMISOLE IN MALE-MICE	9	1
1264	4	1264 1990 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 35(3-4):465-471 MURRAY M; MEHTA I STRUCTURE-ACTIVITY-RELATIONSHIPS IN THE INVITRO MODULATION OF RAT HEPATIC-MICROSOMAL ANDROST-4-ENE-3,17-DIONE HYDROXYLASE- ACTIVITIES BY DERIVATIVES OF 5-ALPHA-ANDROSTANE AND 5-BETA- ANDROSTANE	0	0
1265	10	1265 1990 PHARMACOLOGICAL REVIEWS 42(2):85-101 MURRAY M; REIDY GF SELECTIVITY IN THE INHIBITION OF MAMMALIAN CYTOCHROMES-P-450 BY CHEMICAL-AGENTS	254	7
1266	6	1266 1990 PHARMACOLOGY 40(6):301-311 FUJINO T; WEST D; PARK SS; GELBOIN HV STUDIES ON THE MECHANISM OF MONOCLONAL-ANTIBODY INHIBITION OF ENZYME-ACTIVITY OF PHENOBARBITAL-INDUCED CYTOCHROME-P-450	10	1
1267	25	1267 1990 PHARMACOLOGY & THERAPEUTICS 45(2):153-239 RYAN DE; LEVIN W PURIFICATION AND CHARACTERIZATION OF HEPATIC-MICROSOMAL CYTOCHROME-P-450	358	7
1268	2	1268 1990 PHARMACOLOGY & TOXICOLOGY 66(3):231-233 DALVI RR; MUTINGA ML COMPARATIVE-STUDIES OF THE EFFECTS ON LIVER AND LIVER MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM BY THE FUNGICIDES CAPTAN, CAPTAFOL AND FOLPET IN RATS	6	0
1269	1	1269 1990 TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY 29(2):121-126 SONI MG; NOMIYAMA H; NOMIYAMA K CHRONIC INHALATION EFFECTS OF TRICHLOROETHYLENE ON HEPATIC- MICROSOMAL MIXED-FUNCTION OXIDASE SYSTEM IN RATS	1	0
1270	1	1270 1990 TOXICOLOGY AND APPLIED PHARMACOLOGY 105(2):333-339 FLOREANI M; CARPENEDO F INHIBITION OF RAT-LIVER MONOOXYGENASE ACTIVITIES BY 2-METHYL- 1,4-NAPHTHOQUINONE (MENADIONE)	5	0
1271	2	1271 1990 VOPROSY MEDITSINSKOI KHIMII 36(2):14-18 SHARAPOV VI; GREK OR; ZYKOV AA EFFECT OF ALPHA-TOCOPHEROL AND LIDOCAINE ON STRUCTURE- FUNCTIONAL ALTERATIONS IN LIVER-TISSUE ENDOPLASMIC-RETICULUM MEMBRANES AFTER INDUCTION WITH PHENOBARBITAL DURING POSTISCHEMIC PERIOD	0	0
1272	1	1272 1990 XENOBIOTICA 20(6):591-600 STEFEK M; RANSOM RW; DISTEFANO EW; CHO AK THE ALPHA-CARBON OXIDATION OF SOME PHENCYCLIDINE ANALOGS BY RAT-TISSUE AND ITS PHARMACOLOGICAL IMPLICATIONS	3	0
1273	8	1273 1990 XENOBIOTICA 20(7):711-726 COTTRELL S; HARTMAN GC; LEWIS DFV; PARKE DV STUDIES ON THE CYTOCHROME-P-450 OF AVOCADO (PERSA-AMERICANA) MESOCARP MICROSOMAL FRACTION	6	0
1274	6	1274 1990 XENOBIOTICA 20(9):967-978 VROMANS RM; VANDESTRAAT R; GROENEVELD M; VERMEULEN NPE ONE-ELECTRON REDUCTION OF MITOMYCIN-C BY RAT-LIVER - ROLE OF CYTOCHROME-P-450 AND NADPH-CYTOCHROME-P-450 REDUCTASE	16	4
1275	2	1275 1991 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 31():339-369 MCGIFF JC CYTOCHROME-P-450 METABOLISM OF ARACHIDONIC-ACID	227	0
1276	3	1276 1991 ARCHIV DER PHARMAZIE 324(3):161-164 KOUROUNAKIS PN; REKKA E INDUCTION OF DRUG-METABOLISM CAN BE A HOMEOSTATIC RESPONSE	2	0
1277	2	1277 1991 BIOCHEMICAL PHARMACOLOGY 41(2):229-235 CHAPMAN DE; HOLBROOK DJ; CHANEY SG; HALL IH; LEE KH INVIVO AND INVITRO EFFECTS OF HELENALIN ON MOUSE HEPATIC- MICROSOMAL CYTOCHROME-P450	1	0
1278	4	1278 1991 BIOCHEMICAL PHARMACOLOGY 41(3):411-417 MCKILLOP D; PICKUP KJ DIFFERENT INHIBITION AND INDUCTION PROFILES OF HEPATIC DRUG- METABOLISM IN RATS AND DOGS BY 2 STRUCTURALLY RELATED PYRIDYL DIAZINONE CARDIOTONIC AGENTS	1	0
1279	1	1279 1991 BIOCHEMICAL PHARMACOLOGY 41(9):1325-1330 VINCENT SH; WANG RW; KARANAM BV; KLIMKO M; ALVARO R; CHIU SHL EFFECTS OF THE IMMUNOSUPPRESSANT-FK-506 AND ITS ANALOG-FK-520 ON HEPATIC AND RENAL CYTOCHROME-P450 MIXED-FUNCTION OXIDASE	10	0
1280	8	1280 1991 BIOCHEMICAL PHARMACOLOGY 42(1):97-101 OMATA Y; FRIEDMAN FK A FLUORESCENCE STUDY OF THE INTERACTIONS OF BENZO[A]PYRENE, CYTOCHROME-P450C AND NADPH CYTOCHROME-P450 REDUCTASE	7	2
1281	1	1281 1991 BIOCHEMICAL PHARMACOLOGY 42(3):702-704 HADASOVA E; SIEGMUND W; FRANKE G; SCHNEIDER T; BEYRICH A; BLEYER H; HUBNER G DRUG OXIDATION AND N-ACETYLATION IN RATS PRETREATED WITH SUBTOXIC DOSES OF STREPTOLYSIN-O	10	4
1282	6	1282 1991 BIOCHEMISTRY 30(38):9319-9327 NARASIMHULU S INHIBITION OF SUBSTRATE BINDING TO THE ADRENAL CYTOCHROME- P450C-21 BY ACRYLAMIDE AND ITS IMPLICATIONS FOR SOLVENT ACCESSIBILITY OF THE BINDING-SITE IN THE MICROSOMES	5	1
1283	2	1283 1991 BIOCHEMISTRY 30(50):11646-11653 SAMOKYSZYN VM; DEMONTELLANO PRO TOPOLOGY OF THE CHLOROPEROXIDASE ACTIVE-SITE - REGIOSPECIFICITY OF HEME MODIFICATION BY PHENYLHYDRAZINE AND SODIUM-AZIDE	21	0
1284	3	1284 1991 BIOCHIMICA ET BIOPHYSICA ACTA 1092(3):284-290 KALAPOS MP; GARZO T; ANTONI F; MANDL J EFFECT OF METHYLGLYOXAL ON GLUCOSE FORMATION, DRUG OXIDATION AND GLUTATHIONE CONTENT IN ISOLATED MURINE HEPATOCYTES	17	3
1285	3	1285 1991 CHEMICO-BIOLOGICAL INTERACTIONS 77(1):81-96 SCHEPER T; APPEL KE; SCHUNACK W; SOMOGYI A; HILDEBRANDT AG METABOLIC DENITROSATION OF N-NITROSO-N-METHYLANILINE - DETECTION OF AMINE-METABOLITES	12	0
1286	9	1286 1991 EUROPEAN JOURNAL OF BIOCHEMISTRY 197(2):381-390 KUHNVELTEN WN THERMODYNAMICS AND MODULATION OF PROGESTERONE MICROCOMPARTMENTATION AND HYDROPHOBIC INTERACTION WITH CYTOCHROME-P450XVII BASED ON QUANTIFICATION OF LOCAL LIGAND CONCENTRATIONS IN A COMPLEX MULTICOMPONENT SYSTEM	11	0
1287	3	1287 1991 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 16(1):1-7 IKEDIOBI CO; KWANASHIE HO; OSUIDE G; WAMBEBE C EFFECTS OF CIMETIDINE ON DRUG-METABOLISM IN RAT PUPS	0	0
1288	4	1288 1991 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 16(1):9-13 KOUROUNAKIS PN; REKKA E; DEMOPOULOS VJ; RETSAS S EFFECT OF THE POSITION OF THE CYANO-GROUP OF CYANOPREGNENOLONES ON THEIR DRUG METABOLIC INDUCING ACTIVITY	0	0
1289	3	1289 1991 JOURNAL OF ORGANIC CHEMISTRY 56(3):1260-1266 TUCK SF; ROBINSON CH; SILVERTON JV ASSESSMENT OF THE ACTIVE-SITE REQUIREMENTS OF LANOSTEROL 14- ALPHA-DEMETHYLASE - EVALUATION OF NOVEL SUBSTRATE-ANALOGS AS COMPETITIVE INHIBITORS	10	0
1290	2	1290 1991 KHIMIKO-FARMATSEVTICHESKII ZHURNAL 25(11):4-7 SHIPULINA NV; KOVALEV IY THE NATURAL IMMUNOSTIMULANT TAFTSIN AS A SUBSTRATE AND REGULATOR OF CYTOCHROME-P-450 FUNCTION	0	0
1291	4	1291 1991 LIPIDS 26(8):584-597 MERCER EI STEROL BIOSYNTHESIS INHIBITORS - THEIR CURRENT STATUS AND MODES OF ACTION	45	0
1292	1	1292 1991 MOLECULAR & GENERAL GENETICS 227(2):238-244 HARDER PA; OKEEFE DP; ROMESSER JA; LETO KJ; OMER CA ISOLATION AND CHARACTERIZATION OF STREPTOMYCES-GRISEOLUS DELETION MUTANTS AFFECTED IN CYTOCHROME-P-450-MEDIATED HERBICIDE METABOLISM	9	0
1293	3	1293 1991 MOLECULAR PHARMACOLOGY 39(3):275-280 RAUCY JL; LASKER JM; KRANER JC; SALAZAR DE; LIEBER CS; CORCORAN GB INDUCTION OF CYTOCHROME-P450IIE1 IN THE OBESE OVERFED RAT	59	0
1294	1	1294 1991 MUTATION RESEARCH 261(1):29-39 MCGREGOR DB; EDWARDS I; WOLF CR; FORRESTER LM; CASPARY WJ ENDOGENOUS XENOBIOTIC ENZYME LEVELS IN MAMMALIAN-CELLS	21	0
1295	2	1295 1991 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 41(2):207-219 RUDER FJ; GUYER W; BENSON JA; KAYSER H THE THIOUREA INSECTICIDE ACARICIDE DIAFENTHIURON HAS A NOVEL MODE OF ACTION - INHIBITION OF MITOCHONDRIAL RESPIRATION BY ITS CARBODIIMIDE PRODUCT	14	1
1296	6	1296 1991 PHARMAZIE 46(4):241-246 HOFFMANN P; PANKOW D THE IMPORTANCE OF THE MICROSOMAL ETHANOL OXIDIZING SYSTEM FOR THE METABOLISM OF DRUG AND POLLUTANTS	3	0
1297	2	1297 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(20):9141-9145 LARSON JR; COON MJ; PORTER TD PURIFICATION AND PROPERTIES OF A SHORTENED FORM OF CYTOCHROME- P-450 2E1 - DELETION OF THE NH2-TERMINAL MEMBRANE-INSERTION SIGNAL PEPTIDE DOES NOT ALTER THE CATALYTIC ACTIVITIES	45	0
1298	1	1298 1991 RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY 72(3):371-374 ISHIKAWA M; OZAKI M; TAKAYANAGI Y; SASAKI K DOXAPRAM INHIBITS THE INVITRO OXIDATION OF HEXOBARBITAL	2	0
1299	4	1299 1991 TOXICOLOGY LETTERS 58(2):181-191 KALAPOS MP; SCHAFF Z; GARZO T; ANTONI F; MANDL J ACCUMULATION OF PHENOLS IN ISOLATED HEPATOCYTES AFTER PRETREATMENT WITH METHYLGLYOXAL	12	2
1300	1	1300 1991 XENOBIOTICA 21(1):65-73 KRETZ O; CREPPY EE; DIRHEIMER G DISPOSITION OF THE TOXIC PROTEIN, BOLESATINE, IN RATS - ITS RESISTANCE TO PROTEOLYTIC-ENZYMES	13	0

#	Cited nodes	Nodes / Authors	GCS	LCS
1301	1	1301 1991 XENOBIOTICA 21(2):141-145 LIPPI A; GERVASI PG; BELLUCCI G; MARIONI F; LUZZANI F; VENTURA P EFFECT OF A TERPENOID, (-)-6-HYDROXY-4-(1-HYDROXY-1- METHYLETHYL)-1-CYCLOHEXENE-1-ETHANOL, ON DRUG-METABOLIZING- ENZYMES AND GLUTATHIONE CONTENT IN RAT-LIVER AND LUNG	0	0
1302	7	1302 1991 XENOBIOTICA 21(5):669-678 ANTIGNAC E; KOCH B; DELAFORGE M; NARBONNE JF INVITRO EFFECTS OF AN IMIDAZOLE ANTIFUNGAL, PROCHLORAZ, ON SPECTRAL AND CATALYTIC PROPERTIES OF MICROSOMAL CYTOCHROMES-P- 450	1	0
1303	6	1303 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 292(1):287-294 GOLLY I; HLAVICA P CHEMICAL MODIFICATION OF LYSINE RESIDUES IN CYTOCHROME-P450LM2 (P450IIB4) - INFLUENCE ON HEME LIGANDING OF ARYLAMINES	8	0
1304	1	1304 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 293(1):187-194 KOCHS G; WERCKREICHHART D; GRISEBACH H FURTHER CHARACTERIZATION OF CYTOCHROME-P450 INVOLVED IN PHYTOALEXIN SYNTHESIS IN SOYBEAN - CYTOCHROME-P450 CINNAMATE 4- HYDROXYLASE AND 3,9-DIHYDROXYPTEROCARPAN 6A-HYDROXYLASE	22	0
1305	1	1305 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 294(2):454-460 VINCENT SH; KARANAM BV; PAINTER SK; CHIU SHL INVITRO METABOLISM OF FK-506 IN RAT, RABBIT, AND HUMAN LIVER- MICROSOMES - IDENTIFICATION OF A MAJOR METABOLITE AND OF CYTOCHROME P450-3A AS THE MAJOR ENZYMES RESPONSIBLE FOR ITS METABOLISM	76	1
1306	2	1306 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 297(1):123-131 SALMON F; TATON M; BENVENISTE P; RAHIER A PLANT STEROL BIOSYNTHESIS - NOVEL POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450-DEPENDENT OBTUSIFOLIOL 14-ALPHA- METHYL DEMETHYLASE	18	1
1307	11	1307 1992 BIOCHEMICAL JOURNAL 284():483-490 VERMEIR M; BOENS N; HEIRWEGH KPM INTERACTION OF 7-N-ALKOXYCOUMARINS WITH CYTOCHROME-P-450(2) AND THEIR PARTITIONING INTO LIPOSOMAL MEMBRANES - ASSESSMENT OF METHODS FOR DETERMINATION OF MEMBRANE PARTITION-COEFFICIENTS	5	0
1308	3	1308 1992 BIOCHEMICAL PHARMACOLOGY 43(2):343-352 GOEPTAR AR; TEKOPPELE JM; VANMAANEN JMS; ZOETEMELK CEM; VERMEULEN NPE ONE-ELECTRON REDUCTIVE BIOACTIVATION OF 2,3,5,6- TETRAMETHYLBENZOQUINONE BY CYTOCHROME-P450	22	3
1309	1	1309 1992 BIOCHEMICAL PHARMACOLOGY 43(9):1907-1910 NAKURA H; ITOH S; KUSANO H; ISHIZONE H; IMAOKA S; FUNAE Y; YOKOI T; KAMATAKI T DECREASE IN THE CONTENT OF CYTOCHROME P450IIE BY FASTING IN LIVER-MICROSOMES OF HOUSE MUSK SHREW (SUNCUS-MURINUS)	11	2
1310	5	1310 1992 BIOCHEMICAL PHARMACOLOGY 44(2):251-259 WALTON MI; WOLF CR; WORKMAN P THE ROLE OF CYTOCHROME-P450 AND CYTOCHROME-P450 REDUCTASE IN THE REDUCTIVE BIOACTIVATION OF THE NOVEL BENZOTRIAZINE DI-N- OXIDE HYPOXIC CYTOTOXIN 3-AMINO-1,2,4-BENZOTRIAZINE-1,4-DIOXIDE (SR-4233, WIN-59075) BY MOUSE-LIVER	53	0
1311	1	1311 1992 BIOCHEMICAL PHARMACOLOGY 44(10):2021-2027 GHOSH SK; PODDAR MK EFFECT OF DELTA-9-TETRAHYDROCANNABINOL AND THEOPHYLLINE ON HEPATIC-MICROSOMAL DRUG-METABOLIZING-ENZYMES	3	1
1312	3	1312 1992 BIOCHEMISTRY 31(31):7155-7159 TSOKOS DC; OMATA Y; ROBINSON RC; KRUTZSCH HC; GELBOIN HV; FRIEDMAN FK A PROTEOLYTICALLY SENSITIVE REGION COMMON TO SEVERAL RAT-LIVER CYTOCHROMES-P450 - EFFECT OF CLEAVAGE ON SUBSTRATE BINDING	11	0
1313	9	1313 1992 BIOCHEMISTRY 31(37):8862-8867 OMATA Y; FRIEDMAN FK CYTOCHROME-P450 BENZPHETAMINE INTERACTIONS IN THE ENDOPLASMIC- RETICULUM - STUDIES USING A MONOCLONAL-ANTIBODY TO P450B	3	0
1314	2	1314 1992 CARCINOGENESIS 13(1):95-100 KENSLER TW; GROOPMAN JD; EATON DL; CURPHEY TJ; ROEBUCK BD POTENT INHIBITION OF AFLATOXIN-INDUCED HEPATIC TUMORIGENESIS BY THE MONOFUNCTIONAL ENZYME INDUCER 1,2-DITHIOLE-3-THIONE	60	0
1315	6	1315 1992 CHEMICAL & PHARMACEUTICAL BULLETIN 40(5):1247-1251 MORITA K; KONISHI H; SHIMAKAWA H FLUCONAZOLE - A POTENT INHIBITOR OF CYTOCHROME-P-450-DEPENDENT DRUG-METABOLISM IN MICE AND HUMANS INVIVO - COMPARATIVE-STUDY WITH KETOCONAZOLE	25	0
1316	3	1316 1992 CHEMICO-BIOLOGICAL INTERACTIONS 81(3):271-289 LAURIAULT VV; KHAN S; OBRIEN PJ HEPATOCYTE CYTOTOXICITY INDUCED BY VARIOUS HEPATOTOXINS MEDIATED BY CYTOCHROME P-450IIE1 - PROTECTION WITH DIETHYLDITHIOCARBAMATE ADMINISTRATION	31	1
1317	7	1317 1992 CHEMICO-BIOLOGICAL INTERACTIONS 83(3):249-269 GOEPTAR AR; TEKOPPELE JM; NEVE EPA; VERMEULEN NPE REDUCTASE AND OXIDASE ACTIVITY OF RAT-LIVER CYTOCHROME-P450 WITH 2,3,5,6-TETRAMETHYLBENZOQUINONE AS SUBSTRATE	9	2
1318	3	1318 1992 DRUG METABOLISM AND DISPOSITION 20(1):108-112 VAZ ADN; COON MJ; PEEGEL H; MENON KMJ SUBSTITUTED PYRIDINES - NONSTEROIDAL INHIBITORS OF HUMAN PLACENTAL AROMATASE CYTOCHROME-P-450	9	0
1319	2	1319 1992 EUROPEAN JOURNAL OF BIOCHEMISTRY 210(3):741-746 VOZNESENSKY AI; SCHENKMAN JB INHIBITION OF CYTOCHROME-P450 REDUCTASE BY POLYOLS HAS AN ELECTROSTATIC NATURE	18	1
1320	3	1320 1992 HEPATOLOGY 15(2):276-281 LEE SM; CLEMENS MG EFFECT OF ALPHA-TOCOPHEROL ON HEPATIC MIXED-FUNCTION OXIDASES IN HEPATIC ISCHEMIA REPERFUSION	23	4
1321	1	1321 1992 INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS 29(6):516-518 PATIL SS; MAKHIJA SJ; PAWAR SS PURIFICATION OF ERYTHROCYTE CYTOCHROME-P-450 FROM GOAT AND CHICK	3	0
1322	2	1322 1992 REVISTA MEDICA DE CHILE 120(5):539-544 CARRASCO M; GAULE C; VEGA P; DELVILLAR E INVITRO AND INVIVO INHIBITION OF CYTOCHROME-P50 BY H2 ANTAGONISTS IN RAT-LIVER	1	0
1323	3	1323 1992 TOXICOLOGY AND APPLIED PHARMACOLOGY 114(2):197-203 TESTAL E; GEMMA S; VITTOZZI L BIOACTIVATION OF CHLOROFORM IN HEPATIC MICROSOMES FROM RODENT STRAINS SUSCEPTIBLE OR RESISTANT TO CHCL3 CARCINOGENICITY	21	0
1324	1	1324 1992 TOXICOLOGY LETTERS 60(3):299-305 DALVI RR ALTERATIONS IN HEPATIC PHASE-I AND PHASE-II BIOTRANSFORMATION ENZYMES BY GARLIC OIL IN RATS	22	0
1325	1	1325 1992 TOXICOLOGY LETTERS 61(2-3):125-139 ELTOM SE; BABISH JG; FERGUSON DC THE INTERACTION OF L-TRIIODOTHYRONINE AND 2,3,7,8- TETRACHLORODIBENZO-PARA-DIOXIN ON AH-RECEPTOR-MEDIATED HEPATIC PHASE-I AND PHASE-II ENZYMES AND IODOTHYRONINE 5'-DEIODINASE IN THYROIDECTOMIZED RATS	10	0
1326	5	1326 1993 ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH 43-2(10):1076-1078 SIEGMUND W; WOLFLE G; FRANKE G; AMON I EFFECTS OF NOCLOPROST ON SOME MONOOXYGENASES OF RAT AND HUMAN LIVER	0	0
1327	4	1327 1993 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 193(1):40-46 WOLDMAN YY; WEINER LM; LYAKHOVICH VV DIFFERENT STRUCTURE OF THE COMPLEXES OF 2 CYTOCHROME-P-450 ISOZYMES WITH ACETANILIDE BY H-1-NMR RELAXATION AND SPECTROPHOTOMETRY	2	0
1328	2	1328 1993 BIOCHEMICAL PHARMACOLOGY 45(8):1725-1728 GHOSH SK; PODDAR MK DELTA-9-TETRAHYDROCANNABINOL INHIBITS THE BINDING OF THEOPHYLLINE TO MAMMALIAN NEURONAL AND NONNEURONAL MEMBRANES	2	0
1329	1	1329 1993 BIOCHEMISTRY 32(38):9875-9880 MCMILLAN K; MASTERS BSS OPTICAL-DIFFERENCE SPECTROPHOTOMETRY AS A PROBE OF RAT-BRAIN NITRIC-OXIDE SYNTHASE HEME-SUBSTRATE INTERACTION	122	6
1330	4	1330 1993 BIOCHIMICA ET BIOPHYSICA ACTA 1158(1):83-90 HLAVICA P; KUNZELMULAS U METABOLIC N-OXIDE FORMATION BY RABBIT-LIVER MICROSOMAL CYTOCHROME-P-4502B4 - INVOLVEMENT OF SUPEROXIDE IN THE NADPH- DEPENDENT N-OXYGENATION OF N,N-DIMETHYLANILINE	7	0
1331	2	1331 1993 BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 50(6):817-822 TERSE PS; SAWANT SG; DALVI RR BENOMYL TOXICITY IN CHICKENS	0	0
1332	3	1332 1993 CARCINOGENESIS 14(5):1013-1019 GUTTENPLAN JB EFFECTS OF CYTOSOL ON MUTAGENESIS INDUCED BY N- NITROSODIMETHYLAMINE, N-NITROSOMETHYLUREA AND ALPHA-ACETOXY-N- NITROSODIMETHYLAMINE IN DIFFERENT STRAINS OF SALMONELLA - EVIDENCE FOR DIFFERENT ULTIMATE MUTAGENS FROM N- NITROSODIMETHYLMINE	7	0
1333	1	1333 1993 EAST AFRICAN MEDICAL JOURNAL 70(3):151-153 NYANDIEKA HS; WAKHISI J THE IMPACT OF VITAMINS A,C,E, AND SELENIUM COMPOUND ON PREVENTION OF LIVER-CANCER IN RATS	2	0
1334	18	1334 1993 ENDOCRINE RESEARCH 19(4):223-258 NARASIMHULU S ON THE MODEL CONTROVERSY FOR SUBSTRATE-INDUCED SPIN-STATE TRANSITION IN CYTOCHROME-P450 - (A NEW PERSPECTIVE)	1	0
1335	2	1335 1993 EUROPEAN JOURNAL OF BIOCHEMISTRY 218(2):355-361 PEYRONNEAU MA; RENAUD JP; JAOUEN M; URBAN P; CULLIN C; POMPON D; MANSUY D EXPRESSION IN YEAST OF 3 ALLELIC CDNAS CODING FOR HUMAN LIVER P-450 3A4 - DIFFERENT STABILITIES, BINDING-PROPERTIES AND CATALYTIC ACTIVITIES OF THE YEAST-PRODUCED ENZYMES	13	0
1336	2	1336 1993 FUNDAMENTAL & CLINICAL PHARMACOLOGY 7(2):69-75 SEREE EJ; PISANO PJ; PLACIDI M; RAHMANI R; BARRA YA IDENTIFICATION OF THE HUMAN AND ANIMAL HEPATIC CYTOCHROMES-P450 INVOLVED IN CLONAZEPAM METABOLISM	20	1
1337	2	1337 1993 JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 16(1):106-109 GALTIER P; KADDOURI M; EECKHOUTTE C COMPARED N-DEMETHYLATION OF VETERINARY DRUGS BY MICROSOMES FROM NORMAL AND FLUKE-INFECTED SHEEP LIVERS	4	0
1338	4	1338 1993 JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 16(2):152-163 ELTOM SE; BABISH JG; SCHWARK WS THE POSTNATAL-DEVELOPMENT OF DRUG-METABOLIZING-ENZYMES IN HEPATIC, PULMONARY AND RENAL TISSUES OF THE GOAT	8	1
1339	6	1339 1993 PROGRESS IN LIPID RESEARCH 32(4):357-416 MERCER EI INHIBITORS OF STEROL BIOSYNTHESIS AND THEIR APPLICATIONS	45	0
1340	1	1340 1993 RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY 80(3):375-378 TANI E; KOUROUNAKIS PN ACTION OF OXATOMIDE ON THE HEPATIC-MICROSOMAL ENZYME-SYSTEM - EFFECT OF THE MONOOXYGENASE AND PEROXIDASE-ACTIVITY OF P-450 ON DRUG N-DEMETHYLATIONS	0	0
1341	13	1341 1993 XENOBIOTICA 23(3):227-239 IBA MM; GANDER JE; MANNERING GJ LIPID PEROXIDATION-CYTOCHROME P450 INTERACTIONS - USE OF LINOLEIC-ACID HYDROPEROXIDE IN THE CHARACTERIZATION OF THE SPIN-STATE OF MEMBRANE-BOUND P450	3	0
1342	2	1342 1994 AQUATIC TOXICOLOGY 28(1-2):107-126 FENT K; BUCHELI TD INHIBITION OF HEPATIC-MICROSOMAL MONOOXYGENASE SYSTEM BY ORGANOTINS IN-VITRO IN FRESH-WATER FISH	42	1
1343	4	1343 1994 BIOCHEMICAL PHARMACOLOGY 47(5):893-903 HAASCH ML; GRAF WK; QUARDOKUS EM; MAYER RT; LECH JJ USE OF 7-ALKOXYPHENOXAZONES, 7-ALKOXYCOUMARINS AND 7- ALKOXYQUINOLINES AS FLUORESCENT SUBSTRATES FOR RAINBOW-TROUT HEPATIC MICROSOMES AFTER TREATMENT WITH VARIOUS INDUCERS	16	1
1344	1	1344 1994 BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1192(2):234-240 KOMINAMI S; HARADA D; TAKEMORI S REGULATION MECHANISM OF THE CATALYTIC ACTIVITY OF BOVINE ADRENAL CYTOCHROME P-450(11-BETA)	9	1
1345	2	1345 1994 BIOORGANIC CHEMISTRY 22(3):253-267 HODEK P; STROBEL HW SYNTHESIS AND CHARACTERIZATION OF AZIDOBENZPHETAMINE ANALOGS OF THE CYTOCHROME-P450 SUBSTRATE BENZPHETAMINE	5	1
1346	3	1346 1994 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 107(3):399-404 ARINC E; SEN A IN-VIVO EFFECTS OF THE ANESTHETIC, BENZOCAINE, ON LIVER MICROSOMAL CYTOCHROME-P450 AND MIXED-FUNCTION OXIDASE ACTIVITIES OF GILTHEAD SEABREAM (SPARUS-AURATA)	2	0
1347	4	1347 1994 DRUG METABOLISM AND DISPOSITION 22(1):180-182 FAUX SP; COMBES RD INTERACTION OF CIMETIDINE WITH OXIDIZED AND PREREDUCED MICROSOMAL CYTOCHROME-P-450	3	0
1348	3	1348 1994 EUROPEAN JOURNAL OF BIOCHEMISTRY 222(3):843-850 URBAN P; WERCKREICHHART D; TEUTSCH HG; DURST F; REGNIER S; KAZMAIER M; POMPON D CHARACTERIZATION OF RECOMBINANT PLANT CINNAMATE 4-HYDROXYLASE PRODUCED IN YEAST - KINETIC AND SPECTRAL PROPERTIES OF THE MAJOR PLANT P450 OF THE PHENYLPROPANOID PATHWAY	61	0
1349	1	1349 1994 FOOD AND CHEMICAL TOXICOLOGY 32(4):357-363 LAKE BG; EVANS JG; LEWIS DFV; PRICE RJ STUDIES ON THE ACUTE EFFECTS OF COUMARIN AND SOME COUMARIN DERIVATIVES IN THE RAT	18	0
1350	2	1350 1994 HEPATOLOGY 20(5):1271-1280 YAMADA M; NISHIGAMI T; NAKASHO K; NISHIMOTO Y; MIYAJI H RELATIONSHIP BETWEEN SIGMA-LIKE SITE AND PROGESTERONE-BINDING SITE OF ADULT MALE-RAT LIVER-MICROSOMES	22	0
1351	2	1351 1994 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 26(9):1069-1079 KALAPOS MP; MANDL J; BANHEGYI G; ANTONI F; GARZO T NET GLUCOSE-PRODUCTION FROM ACETONE IN ISOLATED MURINE HEPATOCYTES - THE EFFECT OF DIFFERENT PRETREATMENTS OF MICE	6	1
1352	1	1352 1994 JOURNAL OF BIOCHEMICAL TOXICOLOGY 9(6):297-304 POON R; CHU I; LECAVALIER P; BERGMAN A; VILLENEUVE DC URINARY ASCORBIC-ACID - HPLC DETERMINATION AND APPLICATION AS A NONINVASIVE BIOMARKER OF HEPATIC RESPONSE	20	8
1353	2	1353 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(42):26083-26091 FREY C; NARAYANAN K; MCMILLAN K; SPACK L; GROSS SS; MASTERS BS; GRIFFITH OW L-THIOCITRULLINE - A STEREOSPECIFIC, HEME-BINDING INHIBITOR OF NITRIC-OXIDE SYNTHASES	70	3
1354	2	1354 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(43):26669-26676 GARVEY EP; OPLINGER JA; TANOURY GJ; SHERMAN PA; FOWLER M; MARSHALL S; HARMON MF; PAITH JE; FURFINE ES POTENT AND SELECTIVE-INHIBITION OF HUMAN NITRIC-OXIDE SYNTHASES - INHIBITION BY NON-AMINO ACID ISOTHIOUREAS	184	1
1355	1	1355 1994 JOURNAL OF LIPID RESEARCH 35(3):361-372 OKUDA KI LIVER MITOCHONDRIAL P450 INVOLVED IN CHOLESTEROL CATABOLISM AND VITAMIN-D ACTIVATION	30	1
1356	6	1356 1994 JOURNAL OF PHARMACY AND PHARMACOLOGY 46(5):360-365 VALOTI M; COSTANZO M; SGARAGLI GP; PEREZ V; FERNANDEZALVAREZ E; UNZETA M INTERACTIONS OF MONOAMINE-OXIDASE INHIBITORS, N-ACETYLENIC ANALOGS OF TRYPTAMINE, WITH RAT-LIVER MICROSOMAL CYTOCHROME- P450	0	0
1357	2	1357 1994 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 49(3):183-190 VALLES SM; YU SJ; KOEHLER PG DETOXIFYING ENZYMES IN ADULTS AND NYMPHS OF THE GERMAN- COCKROACH - EVIDENCE FOR DIFFERENT MICROSOMAL MONOOXYGENASE SYSTEMS	13	0
1358	2	1358 1995 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 316(1):275-284 JANSSON I; MOLE JE; SCHENKMAN JB THE ISOLATION AND COMPARISON OF MULTIPLE FORMS OF CYP2B FROM UNTREATED AND PHENOBARBITAL-TREATED RABBIT LIVER-MICROSOMES	7	1
1359	3	1359 1995 ARCHIVES OF PHARMACAL RESEARCH 18(3):189-194 PARK MJ; CHO TS; LEE SM THE ROLE OF OXYGEN-FREE RADICALS AND PHOSPHOLIPASE A(2) IN ISCHEMIA-REPERFUSION INJURY TO THE LIVER	0	0
1360	1	1360 1995 ARCHIVES OF TOXICOLOGY 69(9):655-658 UENO S; SUSA N; FURUKAWA Y; SUGIYAMA M ROLE OF CYTOCHROME-P450 IN HEPATOTOXICITY INDUCED BY DIBUTYLTIN AND TRIBUTYLTIN COMPOUNDS IN MICE	9	1
1361	4	1361 1995 BIOCHEMICAL PHARMACOLOGY 49(11):1657-1663 WEI XX; LOI CM; SCHMUCKER DL; VESTAL RE CHARACTERIZATION OF THE INDEPENDENT AND COMBINED EFFECTS OF 2 INHIBITORS ON OXIDATIVE DRUG-METABOLISM IN RAT-LIVER MICROSOMES	4	1
1362	3	1362 1995 CHEMICO-BIOLOGICAL INTERACTIONS 94(3):197-213 LAAKSONEN M; KALISTEKORHONEN E; KARENLAMPI S; HANNINEN O P450 ENZYME CYP2B CATALYZES THE DETOXIFICATION OF DIISOPROPYL FLUOROPHOSPHATE	2	0
1363	5	1363 1995 CHEMICO-BIOLOGICAL INTERACTIONS 97(2):149-168 GOEPTAR AR; TEKOPPELE JM; GLATT HR; GROOT EJ; SEIDEL A; BARRENSCHEEN M; WOLFEL C; DOEHMER J; VERMEULEN NPE THE CYTOTOXICITY OF MITOMYCIN-C AND ADRIAMYCIN IN GENETICALLY- ENGINEERED V79 CELL-LINES AND FRESHLY ISOLATED RAT HEPATOCYTES	6	0
1364	1	1364 1995 CHIRALITY 7(5):376-380 PEPPER C; SMITH HJ; NICHOLLS PJ; BARRELL KJ; AHMADI M ENANTIOSELECTIVITY OF AROMATASE INHIBITORS - SUBSTITUTED 3-(4- AMINOPHENYL)PYRROLIDINE-2,5-DIONES	1	0
1365	16	1365 1995 CRITICAL REVIEWS IN TOXICOLOGY 25(1):25-65 GOEPTAR AR; SCHEERENS H; VERMEULEN NPE OXYGEN AND XENOBIOTIC REDUCTASE ACTIVITIES OF CYTOCHROME-P450	93	1
1366	2	1366 1995 EUROPEAN JOURNAL OF BIOCHEMISTRY 232(1):247-256 DELORME C; PIFFETEAU A; VIGER A; MARQUET A INHIBITION OF BOVINE CYTOCHROME P-450(11-BETA) BY 18- UNSATURATED PROGESTERONE DERIVATIVES	7	0
1367	3	1367 1995 EUROPEAN JOURNAL OF PHARMACOLOGY 294(1):41-46 Lee SM; Kim KH Rebamipide ameliorates hepatic dysfunction induced by ischemia reperfusion in rats	8	0
1368	1	1368 1995 FUNDAMENTAL AND APPLIED TOXICOLOGY 26(2):282-292 CHU I; VILLENEUVE DC; YAGMINAS A; LECAVALIER P; HAKANSSON H; AHLBORG UG; VALLI VE; KENNEDY SW; BERGMAN A; SEEGAL RF; FEELEY M TOXICITY OF PCB-77 (3,3',4,4'-TETRACHLOROBIPHENYL) AND PCB-118 (2,3',4,4',5-PENTACHLOROBIPHENYL) IN THE RAT FOLLOWING SUBCHRONIC DIETARY EXPOSURE	28	4
1369	2	1369 1995 GENERAL PHYSIOLOGY AND BIOPHYSICS 14(3):225-239 HODEK P; BURKHARD J; JANKU J PROBING THE CYTOCHROME-P-450 2B1 ACTIVE-SITE WITH DIAMANTOID COMPOUNDS	7	2
1370	3	1370 1995 IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 17(2):283-300 HADASOVA E; SIEGMUND W; WALTER R; SCHEUCH E; FRANKE G EFFECTS OF STREPTOLYSIN-O, PICIBANIL (OK-432) AND INTERFERON ALPHA-2A ON CYTOCHROME P-450-DEPENDENT MONOOXYGENASES AND ARYLAMINE N-ACETYLTRANSFERASE IN RAT-LIVER	8	3
1371	2	1371 1995 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 53(1-6):103-110 PAPADOPOULOS V; BROWN AS ROLE OF THE PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR AND THE POLYPEPTIDE DIAZEPAM-BINDING INHIBITOR IN STEROIDOGENESIS	46	0
1372	1	1372 1995 TOXICOLOGY AND APPLIED PHARMACOLOGY 135(2):165-171 Ueno S; Susa N; Furukawa Y; Sugiyama M Formation of paramagnetic chromium in liver of mice treated with dichromate (VI)	7	0
1373	2	1373 1995 TOXICOLOGY AND INDUSTRIAL HEALTH 11(3):343-361 POON R; CHU I; BJARNASON S; VINCENT R; POTVIN M; MILLER RB; VALLI VE SHORT-TERM INHALATION TOXICITY OF METHANOL, GASOLINE, AND METHANOL/GASOLINE IN THE RAT	4	0
1374	2	1374 1995 VETERINARY AND HUMAN TOXICOLOGY 37(4):340-342 KODAM KM; GOVINDWAR SP EFFECT OF SULFAMETHAZINE ON MIXED-FUNCTION OXIDASE IN CHICKENS	2	2
1375	1	1375 1996 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 40(8):1875-1880 Mizuki Y; Fujiwara I; Yamaguchi T; Sekine Y Structure-related inhibitory effect of antimicrobial enoxacin and derivatives on theophylline metabolism by rat liver microsomes	2	0
1376	4	1376 1996 BIOCHEMISTRY 35(18):5883-5892 Sennequier N; Stuehr DJ Analysis of substrate-induced electronic, catalytic, and structural changes in inducible NO synthase	46	1
1377	2	1377 1996 BIOCHEMISTRY 35(51):16735-16745 Gorren ACF; List BM; Schrammel A; Pitters E; Hemmens B; Werner ER; Schmidt K; Mayer B Tetrahydrobiopterin-free neuronal nitric oxide synthase: Evidence for two identical highly anticooperative pteridine binding sites	86	1
1378	1	1378 1996 EUROPEAN JOURNAL OF BIOCHEMISTRY 239(2):403-409 Munro AW; Daff S; Coggins JR; Lindsay JG; Chapman SK Probing electron transfer in flavocytochrome P-450 BM3 and its component domains	25	0
1379	5	1379 1996 EXPERIENTIA 52(8):827-830 Kalapos MP; Riba P; Garzo T; Mandl J Glucose formation from methylglyoxal in hepatocytes from streptozotocin-induced diabetic mice: The effect of insulin	3	0
1380	4	1380 1996 IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 18(4):571-586 Walter R; Siegmund W; Scheuch E Effects of interferon-gamma and streptolysin O on hepatic procainamide N-acetyltransferase and various microsomal cytochrome P450-dependent monooxygenases in rats	6	0
1381	2	1381 1996 JOURNAL OF APPLIED TOXICOLOGY 16(2):121-128 Chu I; Villeneuve DC; Yagminas A; Lecavalier P; Poon R; Feeley M; Kennedy SW; Seegal RF; Hakansson H; Ahlborg UG; Valli VE; Bergman A Toxicity of 2,2',4,4',5,5'-hexachlorobiphenyl in rats: Effects following 90-day oral exposure	12	2
1382	5	1382 1996 JOURNAL OF APPLIED TOXICOLOGY 16(4):331-337 Rahman M; Fujii K; Kawamoto M; Yuge O Contrasting effect of isoflurane on drug metabolism: Decreased type I and increased type II substrate metabolism in guinea pig liver microsomes	2	0
1383	1	1383 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 276(1):258-264 Kraner JC; Morgan ET; Poet TS; Born SL; Burnett VL; Halpert JR Suppression of rat hepatic microsomal cytochromes P450 by cyclophosphamide is correlated with plasma thyroid hormone levels and displays differential strain sensitivity	6	0
1384	1	1384 1996 JOURNAL OF SUBMICROSCOPIC CYTOLOGY AND PATHOLOGY 28(1):27-32 Gilroy C; Singh A; Chu I; Villeneuve DC Toxicity of PCB 156 in the rat liver: An ultrastructural and biochemical study	2	0
1385	3	1385 1996 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 49(3):301-318 Chu I; Villeneuve DC; Yagminas A; Lecavalier P; Poon R; Hakansson H; Ahlborg UG; Valli VE; Kennedy SW; Bergman A; Seegal RF; Feeley M Toxicity of 2,4,4'-trichlorobiphenyl in rats following 90-day dietary exposure	10	1
1386	2	1386 1996 MEDICAL SCIENCE RESEARCH 24(4):257-259 Watanabe M; Nakura H; Tateishi T; Tanaka H; Kumai T; Kobayashi S Reduced hepatic drug-metabolising enzyme activities in spontaneously hyperlipidaemic rat as an animal model of hypercholesterolaemia	7	0
1387	5	1387 1996 PHARMAZIE 51(7):493-497 Scheuch E; Walter R; Hadasova E; Amon I; Siegmund W Influence of H-2-receptor- and proton pump inhibitors on some functions of the oxydative and conjugative drug metabolism	3	0
1388	4	1388 1996 PHARMAZIE 51(7):498-500 Walter R; Hadasova E; Scheuch E; Siegmund W Effects of streptolysin O, polyriboinosinic-polyribocytidylic acid and combinations with cyclophosphamide on the hepatic arylamine N-acetyltransferase and cytochrome P450-dependent monooxygenases in rats	3	0
1389	1	1389 1996 TOXICOLOGY 109(2-3):129-146 Poon R; Chu I; Davis H; Yagminas AP; Valli VE Systemic toxicity of a bitumen upgrading product in the rat following subchronic dermal exposure	0	0
1390	1	1390 1996 TOXICOLOGY AND APPLIED PHARMACOLOGY 141(2):507-519 Badger DA; Sauer JM; Hoglen NC; Jolley CS; Sipes IG The role of inflammatory cells and cytochrome P450 in the potentiation of CCl4-induced liver injury by a single dose of retinol	22	2
1391	1	1391 1996 TOXICOLOGY IN VITRO 10(5):577-584 Voskoboinik I; Drew R; Ahokas JT Effect of peroxisome proliferator nafenopin on the cytotoxicity of dihaloalkanes in isolated rat hepatocytes	0	0
1392	3	1392 1996 TOXICOLOGY LETTERS 87(1):25-30 Kodam KM; Adav SS; Govindwar SP Effect of sulfamethazine on phenobarbital and benzo[a]pyrene induced hepatic microsomal mixed function oxidase system in rats	1	1
1393	1	1393 1996 ULTRASTRUCTURAL PATHOLOGY 20(3):275-284 Singh A; Chu I; Villeneuve DC Subchronic toxicity of 2,4,4'-trichlorobiphenyl in the rat liver: An ultrastructural and biochemical study	7	0
1394	1	1394 1996 VOPROSY MEDITSINSKOI KHIMII 42(2):119-124 Lashneva NV; Karge E; Knells U; Klinger V; Splinter FK; Tutelan VA In vitro study of selen influence on the formation of active oxygen species and lipid peroxidation in rat liver microsomes	3	0
1395	3	1395 1996 XENOBIOTICA 26(6):647-666 Bessems JGM; teKoppele JM; VanDijk PA; VanStee LLP; Commandeur JNM; Vermeulen NPE Rat liver microsomal cytochrome P450-dependent oxidation of 3,5-disubstituted analogues of paracetamol	5	0
1396	5	1396 1997 ARCHIV DER PHARMAZIE 330(5):135-140 Gernhardt S; Karge E; Schonecker B; Klinger W Influence of various estrogens on biotransformation: Affinity to cytochrome P-450, structure activity relationships, and scavenger function	1	0
1397	3	1397 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 347(2):181-192 Savas U; Carstens CP; Jefcoate CR Biological oxidations and P450 reactions - Recombinant mouse CYP1B1 expressed in Escherichia coli exhibits selective binding by polycyclic hydrocarbons and metabolism which parallels C3H10T1/2 cell microsomes, but differs from human recombinant CYP1B1	28	1
1398	1	1398 1997 BIOCHEMICAL JOURNAL 328():349-352 Pfeiffer S; Gorren ACF; Pitters E; Schmidt K; Werner ER; Mayer B Allosteric modulation of rat brain nitric oxide synthase by the pterin-site enzyme inhibitor 4-aminotetrahydrobiopterin	32	0
1399	4	1399 1997 BIOCHEMISTRY 36(8):2203-2210 Stresser DM; Kupfer D Catalytic characteristics of CYP3A4: Requirement for a phenolic function in ortho hydroxylation of estradiol and mono-O- demethylated methoxychlor	16	0
1400	1	1400 1997 BIOCHEMISTRY 36(39):11707-11716 Kent UM; Hanna IH; Szklarz GD; Vaz ADN; Halpert JR; Bend JR; Hollenberg PF Significance of glycine 478 in the metabolism of N-benzyl-1- aminobenzotriazole to reactive intermediates by cytochrome P450 2B1	15	0

#	Cited nodes	Nodes / Authors	GCS	LCS
1401	2	1401 1997 BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL 41(2):293-301 Nakura H; Itoh S; Kusano H; Ishizone H; Kamataki T Opposite effects of isoniazid and fasting on the expression of CYP2E1 protein and mRNA in house musk shrew (Suncus murinus)	1	0
1402	2	1402 1997 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1339(2):268-276 Shimizu Y; Kusunose E; Kikuta Y; Arakawa T; Ichihara K; Kusunose M Purification and characterization of two new cytochrome P-450 related to CYP2C subfamily from rabbit small intestine microsomes	3	0
1403	4	1403 1997 BIOLOGIA 52(6):731-740 Hodek P; Burkhard J; Janku J 3-Azidiamantane, a photolabile substrate analogue designed for photoaffinity labelling of phenobarbital-inducible cytochrome P-450	0	0
1404	2	1404 1997 CHEMOSPHERE 34(1):1-12 Poon R; Lecavalier P; Bergman A; Yagminas A; Chu I; Valli VE Effects of tris(4-chlorophenyl)methanol on the rat following short-term oral exposure	14	1
1405	3	1405 1997 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 118(2):185-189 Adav SS; Govindwar SP Effects of aflatoxin B1 on liver microsomal enzymes in different strains of chickens	3	1
1406	2	1406 1997 CRITICAL REVIEWS IN TOXICOLOGY 27(3):273-297 Das M; Khanna SK Clinicoepidemiological, toxicological, and safety evaluation studies on argemone oil	20	0
1407	1	1407 1997 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 22(2):165-171 Klinger W; Oelschlager H; Karge E; Rothley D Interaction of chlormezanone with rat liver microsomes and its degradation	5	2
1408	1	1408 1997 FOOD AND CHEMICAL TOXICOLOGY 35(2):225-239 Poon R; Lecavalier P; Mueller R; Valli VE; Procter BG; Chu I Subchronic oral toxicity of Di-n-octyl phthalate and di(2- ethylhexyl) phthalate in the rat	36	0
1409	2	1409 1997 FREE RADICAL BIOLOGY AND MEDICINE 23(7):963-971 Pahan K; Smith BT; Singh AK; Singh I Cytochrome P-450 2E1 in rat liver peroxisomes: Downregulation by ischemia/reperfusion-induced oxidative stress	8	0
1410	2	1410 1997 HUMAN & EXPERIMENTAL TOXICOLOGY 16(5):262-266 Stott I; Murthy A; Robinson A; Thomas NW; Fry JR Low-dose diethyldithiocarbamate attenuates the hepatotoxicity of 1,3-dichloro-2-propanol and selectively inhibits CYP2E1 activity in the rat	6	0
1411	2	1411 1997 JOURNAL OF CLEAN TECHNOLOGY ENVIRONMENTAL TOXICOLOGY AND OCCUPATIONAL MEDICINE 6(3):299-317 Poon R; Chu I; Bjarnason S; Vincent R; Potvin M; Miller RB; Valli VE Short-term inhalation toxicity of methanol, gasoline, and methanol/gasoline in the rat	0	0
1412	2	1412 1997 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 50(1):53-65 Poon R; Davis HD; Lecavalier P; Liteplo R; Yagminas A; Chu I; Bihun C Effects of benzothiophene on male rats following short-term oral exposure	2	0
1413	4	1413 1997 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 51(3):265-277 Lecavalier P; Chu I; Yagminas A; Villeneuve DC; Poon R; Feeley M; Hakansson H; Ahlborg UG; Valli VE; Bergman A; Seegal RF; Kennedy SW Subchronic toxicity of 2,2',3,3',4,4'-hexachlorobiphenyl in rats	5	0
1414	2	1414 1997 NATURE BIOTECHNOLOGY 15(8):784-788 Parikh A; Gillam EMJ; Guengerich FP Drug metabolism by Escherichia coli expressing human cytochromes P450	83	2
1415	2	1415 1997 PHARMACOLOGICAL RESEARCH 35(5):477-480 Watanabe M; Tanaka M; Tateishi T; Nakura H; Kumai T; Kobayashi S Effects of the estrous cycle and the gender difference on hepatic drug-metabolising enzyme activities	7	0
1416	2	1416 1997 PHARMACOLOGICAL RESEARCH 36(3):249-254 Ceppa L; Dacasto M; Carletti M; Montesissa C; Nebbia C 'In vitro' interactions of monensin with hepatic xenobiotic metabolizing enzymes	4	0
1417	2	1417 1997 STEROIDS 62(1):117-123 Peterson JA; Sevrioukova I; Truan G; GrahamLorence SE P450BM-3: A tale of two domains - Or is it three?	5	0
1418	2	1418 1997 TOXICOLOGY 121(2):143-153 Badger DA; Kuester RK; Sauer JM; Sipes IG Gadolinium chloride reduces cytochrome p450: Relevance to chemical-induced hepatotoxicity	23	1
1419	4	1419 1997 VETERINARY AND HUMAN TOXICOLOGY 39(3):141-146 Kodam KM; Govindwar SP In vivo and in vitro effect of sulfamethazine on hepatic mixed function oxidases in rats	0	0
1420	1	1420 1997 VETERINARY RESEARCH COMMUNICATIONS 21(5):317-323 Deoras DP; YoungCurtis P; Dalvi RR; Tippett FE Effect of gossypol on hepatic and serum gamma- glutamyltransferase activity in rats	0	0
1421	4	1421 1998 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 349(1):95-104 Cvrk T; Strobel HW Photoaffinity labeling of cytochrome P4501A1 with azidocumene: Identification of cumene hydroperoxide binding region	11	0
1422	5	1422 1998 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 353(2):365-373 Hosea NA; Guengerich FP Oxidation of nonionic detergents by cytochrome P450 enzymes	12	0
1423	1	1423 1998 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 248(3):767-772 Nakano K; Sagami I; Daff S; Shimizu T Chiral recognition at the heme active site of nitric oxide synthase is markedly enhanced by L-arginine and 5,6,7,8- tetrahydrobiopterin	2	0
1424	3	1424 1998 BIOCHEMISTRY 37(45):15825-15834 Wengenack NL; Todorovic S; Yu L; Rusnak F Evidence for differential binding of isoniazid by Mycobacterium tuberculosis KatG and the isoniazid-resistant mutant KatG(S315T)	20	0
1425	6	1425 1998 DRUG METABOLISM REVIEWS 30(4):739-786 Lewis DFV; Pratt JM The P450 catalytic cycle and oxygenation mechanism	22	0
1426	1	1426 1998 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 50(4-6):323-329 Oelschlager H; Rothley D; Klinger W; Karge E; Vogelsang H Chromatographic resolution of ciprofibrate and interaction of the racemate and both enantiomers with rat liver microsomes in vitro	0	0
1427	1	1427 1998 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 50(4-6):501-506 Lupp A; Kerst S; Karge E; Quack G; Klinger W Investigation on possible antioxidative properties of the NMDA- receptor antagonists ketamine, memantine, and amantadine in comparison to nicanartine in vitro	2	0
1428	6	1428 1998 FISH PHYSIOLOGY AND BIOCHEMISTRY 18(1):97-106 Moutou KA; Burke MD; Houlihan DF Hepatic P450 monooxygenase response in rainbow trout (Oncorhynchus mykiss (Walbaum)) administered aquaculture antibiotics	1	0
1429	6	1429 1998 JOURNAL OF APPLIED TOXICOLOGY 18(4):285-292 Chu I; Poon R; Yagminas A; Lecavalier P; Hakansson H; Valli VE; Kennedy SW; Bergman A; Seegal RF; Feeley M Subchronic toxicity of PCB 105 (2,3,3 ',4,4 '- entachlorobiphenyl) in rats	8	0
1430	4	1430 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(15):8882-8889 Babu BR; Griffith OW N-5-(1-imino-5-butenyl)-L-ornithine - A neuronal isoform selective mechanism-based inactivator of nitric oxide synthase	37	0
1431	4	1431 1998 MEDICAL SCIENCE RESEARCH 26(10):691-693 Ahmed RS; Pawar SS Effect of inducers on the hepatic microsomal mixed function oxidase system of female rats during food restriction	1	0
1432	3	1432 1998 SOUTH AFRICAN JOURNAL OF SCIENCE 94(6):303-304 Farombi EO; Emerole GO Interference of common antimalarial drugs with some hepatic microsomal components and drug metabolism: potential implications for toxicity	5	0
1433	3	1433 1999 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 263(2):392-397 Osada M; Ogura Y; Yasui H; Sakurai H Involvement of singlet oxygen in cytochrome P450-dependent substrate oxidations	4	0
1434	2	1434 1999 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 266(3):690-698 Omura T Forty years of cytochrome P450	29	0
1435	3	1435 1999 BIOCHEMICAL PHARMACOLOGY 58(10):1547-1555 Lee SM; Cho TS; Kim DJ; Cha YN Protective effect of ethanol against acetaminophen-induced hepatotoxicity in mice - Role of NADH : quinone reductase	2	0
1436	4	1436 1999 BIOCHEMISTRY 38(48):15853-15862 Sono M; Ledbetter AP; McMillan K; Roman LJ; Shea TM; Masters BSS; Dawson JH Essential thiol requirement to restore pterin- or substrate- binding capability and to regenerate native enzyme-type high- spin heme spectra in the Escherichia coli-expressed tetrahydrobiopterin-free oxygenase domain of neuronal nitric oxide synthase	8	0
1437	1	1437 1999 CANCER LETTERS 138(1-2):73-79 Tateishi T; Nakura H; Asoh M; Watanabe M; Tanaka M; Kumai T; Kobayashi S Multiple cytochrome P-450 subfamilies are co-induced with P- glycoprotein by both phenothiazine and 2-acetylaminofluorene in rats	9	0
1438	2	1438 1999 CHEMICO-BIOLOGICAL INTERACTIONS 117(3):257-268 Tateishi T; Asoh M; Nakura H; Watanabe M; Tanaka M; Kumai T; Kobayashi S Carbamazepine induces multiple cytochrome P450 subfamilies in rats	7	0
1439	1	1439 1999 DRUG METABOLISM REVIEWS 31(2):317-331 Estabrook RW Discovering the functions of cytochrome P450 in drug metabolism: The role of Alfred Hildebrandt	0	0
1440	2	1440 1999 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 24(1):63-68 Klinger W; Oelschlager H; Rothley D; Karge E; Seeling A Interaction of chlormezanone enantiomers with rat liver microsomes	1	0
1441	4	1441 1999 INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 75(9):1189-1199 Yukawa O; Nakajima T; Yukawa M; Ozawa T; Yamada T Induction of radical scavenging ability and protection against radiation-induced damage to microsomal membranes following low- dose irradiation	7	0
1442	1	1442 1999 JOURNAL OF HEPATOLOGY 31(2):263-270 Tanaka M; Nakura H; Tateishi T; Watanabe M; Nakaya S; Kumai T; Kobayashi S Ursodeoxycholic acid prevents hepatic cytochrome P450 isozyme reduction in rats with deoxycholic acid-induced liver injury	4	0
1443	6	1443 1999 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A 56(6):433-447 Nebbia C; Ceppa L; Dacasto M; Carletti M Triphenyltin acetate-mediated in vitro inactivation of rat liver cytochrome P-450	6	0
1444	2	1444 1999 MEDICAL SCIENCE RESEARCH 27(9):617-620 Kalapos MP Influence of acetone on the hepatotoxicity of methylglyoxal	1	0
1445	3	1445 1999 TOXICOLOGICAL SCIENCES 52(1):130-139 Inder RE; Bray BJ; Sipes IG; Rosengren RJ Role of cytochrome P4502E1 in retinol's attenuation of carbon tetrachloride-induced hepatotoxicity in the Swiss Webster mouse	3	0
1446	4	1446 1999 VETERINARY AND HUMAN TOXICOLOGY 41(4):210-212 Govindwar SP; Adav SS Effects of aflatoxin B-1 on the hepatic microsomal mixed function oxidase system during phenobarbital and benzo(a)pyrene treatment in chickens	0	0
1447	1	1447 1999 WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY 15(2):259-263 Salokhe MD; Govindwar SP Effect of carbon source on the biotransformation enzymes in Serratia marcescens	0	0
1448	4	1448 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 276(2):762-766 LeLean JE; Moon N; Dunham WR; Coon MJ EPR spectrometry of cytochrome P4502B4: Effects of mutations and substrate binding	3	0
1449	3	1449 2000 BIOCHEMISTRY 39(20):5929-5939 Hosea NA; Miller GP; Guengerich FP Elucidation of distinct ligand binding sites for cytochrome P450 3A4	53	3
1450	1	1450 2000 BIOTECHNOLOGY LETTERS 22(1):3-8 Engler KH; Kelly SL; Coker RD; Evans IH Toxin-binding properties of cytochrome P450 in Saccharomyces cerevisiae and Kluyveromyces marxianus	1	0
1451	4	1451 2000 COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS 65(1):122-132 Borek-Dohalska L; Hodek P; Stiborova M New selective inhibitors of cytochrome P4502B4 and an activator of cytochrome P450 3A6 in rabbit liver microsomes	3	0
1452	2	1452 2000 JOURNAL OF APPLIED TOXICOLOGY 20(6):455-461 Poon R; Nadeau B; Chu I Biochemical effects of chloral hydrate on male rats following 7-day drinking water exposure	2	0
1453	1	1453 2000 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 35(2):227-233 Satake N; Imanishi M; Keto Y; Yamada H; Ishikawa M; Shibata S Genistein potentiates the relaxation induced by beta(1)- and beta(2)-adrenoceptor activation in rat aortic rings	3	0
1454	2	1454 2000 LIFE SCIENCES 66(22):2193-2212 Fontaine F; de Sousa G; Burcham PC; Duchene P; Rahmani R Role of cytochrome P450 3A in the metabolism of mefloquine in human and animal hepatocytes	2	0
1455	3	1455 2000 SHOCK 13(4):279-284 Lee SM; Park MJ; Cho TS; Clemens MG Hepatic injury and lipid peroxidation during ischemia and reperfusion	8	2
1456	2	1456 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 385(2):290-300 Cvrk T; Strobel HW Role of LYS271 and LYS279 residues in the interaction of cytochrome P4501A1 with NADPH-cytochrome P450 reductase	4	0
1457	1	1457 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 393(2):255-261 Hanna IH; Kim MS; Guengerich FP Heterologous expression of cytochrome P450 2D6 mutants, electron transfer, and catalysis of bufuralol hydroxylation: The role of aspartate 301 in structural integrity	13	3
1458	3	1458 2001 BIOCHEMISTRY 40(16):5018-5031 Guryev OL; Gilep AA; Usanov SA; Estabrook RW Interaction of apo-cytochrome b(5) with cytochromes P4503A4 and P45017A: Relevance of heme transfer reactions	12	0
1459	4	1459 2001 BIOCHEMISTRY 40(24):7262-7272 Miller GP; Guengerich FP Binding and oxidation of alkyl 4-nitrophenyl ethers by rabbit cytochrome P450 1A2: Evidence for two binding sites	9	1
1460	3	1460 2001 BIOCHEMISTRY 40(47):14215-14223 Miller GP; Hanna IH; Nishimura Y; Guengerich FP Oxidation of phenethylamine derivatives by cytochrome P450 2D6: The issue of substrate protonation in binding and catalysis	9	3
1461	3	1461 2001 BIOLOGICAL CHEMISTRY 382(11):1541-1549 Winter J; Eckerskorn C; Waditschatka R; Kayser H A microsomal ecdysone-binding cytochrome P450 from the insect Locusta migratoria purified by sequential use of type-II and type-I ligands	1	0
1462	5	1462 2001 CHEMICO-BIOLOGICAL INTERACTIONS 138(1):85-106 Boek-Dohalska L; Hodek P; Sulc M; Stiborova M alpha-naphthoflavone acts as activator and reversible or irreversible inhibitor of rabbit microsomal CYP3A6	1	0
1463	3	1463 2001 CONTRACEPTION 64(4):261-269 Ghosh R; Kamboj VP; Singh MM Interaction with anti-implantation and estrogen antagonistic activities of dl-ormeloxifene, a selective estrogen receptor modulator, by tetracycline in female Sprague-Dawley rats	0	0
1464	9	1464 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(18):4817-4832 Hlavica P; Lewis DFV Allosteric phenomena in cytochrome P450-catalyzed monooxygenations	2	0
1465	3	1465 2001 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 26(1-2):31-35 Klinger W; Karge E; Demme U; Kretzschmar M Interactions of melatonin with the liver microsomal cytochrome P450 system of rats and humans in vitro and effects on the P450 system and the antioxidative status in rat liver after acute treatment	0	0
1466	2	1466 2001 JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 24(4):299-302 Hunter RP; Short CR; Dees AA Interaction of cimetidine with equine hemoglobin	0	0
1467	3	1467 2001 PEST MANAGEMENT SCIENCE 57(10):975-980 Kayser H; Eilinger P Metabolism of diafenthiuron by microsomal oxidation: procide activation and inactivation as mechanisms contributing to selectivity	0	0
1468	2	1468 2001 XENOBIOTICA 31(4):223-237 Sakuma T; Honma R; Maguchi S; Tamaki H; Nemoto N Different expression of hepatic and renal cytochrome P450s between the streptozotocin-induced diabetic mouse and rat	4	0
1469	4	1469 2002 BIOCHEMISTRY 41(36):11025-11034 Guengerich FP; Miller GP; Hanna IH; Martin MV; Leger S; Black C; Chauret N; Silva JM; Trimble LA; Yergey JA; Nicoll-Griffith DA Diversity in the oxidation of substrates by cytochrome P450 2D6: Lack of an obligatory role of aspartate 301 - Substrate electrostatic bonding	8	2
1470	4	1470 2002 JOURNAL OF HEPATOLOGY 36(1):72-77 Seo MY; Lee SM Protective effect of low dose of ascorbic acid on hepatobiliary function in hepatic ischemia/reperfusion in rats	2	0
1471	1	1471 2002 TOXICOLOGY LETTERS 128(1-3):129-144 Klinger W; Lupp A; Karge E; Baumbach H; Eichhorn F; Feix A; Fuldner F; Gernhardt S; Knels L; Kost B; Mertens G; Werner F; Oettel M; Romer W; Schwarz S; Elger W; Schneider B Estradiol, testosterone,, dehydroepiandrosterone and androstenedione: novel derivatives and enantiomers. Interactions with rat liver microsomal cytochrome P450 and antioxidant/radical scavenger activities in vitro	2	0
1472	2	1472 2003 ARCHIVES OF PHARMACAL RESEARCH 26(1):47-52 Lee WY; Lee SM The roles of Kupffer cells in hepatocellular dysfunction after femur fracture trauma in rats	0	0
1473	4	1473 2003 BIOCHEMISTRY 42(5):1245-1253 Guengerich FP; Hanna IH; Martin MV; Gillam EMJ Role of glutamic acid 216 in cytochrome P450 2D6 substrate binding and catalysis	0	0
1474	3	1474 2003 CHEMICAL RESEARCH IN TOXICOLOGY 16(4):450-459 Hutzler JM; Walker GS; Wienkers LC Inhibition of cytochrome P450 2D6: Structure-activity studies using a series of quinidine and quinine analogues	0	0
1475	2	1475 2003 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 523():173-182 Guengerich FP; Chun YJ; Kim D; Gillam EMJ; Shimada T Cytochrome P4501B1: a target for inhibition in anticarcinogenesis strategies	1	0
1476	2	1476 2003 XENOBIOTICA 33(6):603-613 Ueng YF; Kuo YH; Peng HC; Chen TL; Jan WC; Guengerich FP; Lin YL Diterpene quinone tanshinone IIA selectively inhibits mouse and human cytochrome P4501A2	0	0

Page 3:  1  2  3
Generated by: HistCite(Vlad). Version: 2003.05.01