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Author(s): Koopman WJH (Koopman, Werner J. H.); Nijtmans LGJ (Nijtmans, Leo G. J.); Dieteren CEJ (Dieteren, Cindy E. J.); Roestenberg P (Roestenberg, Peggy); Valsecchi F (Valsecchi, Federica); Smeitink JAM (Smeitink, Jan A. M.); Willems PHGM (Willems, Peter H. G. M.)
Title: Mammalian Mitochondrial Complex I: Biogenesis, Regulation, and Reactive Oxygen Species Generation
Source: ANTIOXIDANTS & REDOX SIGNALING 12 (12): 1431-1470
Date: 2010 JUN
Document Type: Journal : Review
DOI: 10.1089/ars.2009.2743
Language: English
Comment:
Address: Radboud Univ Nijmegen, Med Ctr, Nijmegen Ctr Mol Life Sci, Dept Biochem, NL-6500 HB Nijmegen, Netherlands.
Radboud Univ Nijmegen, Med Ctr, Nijmegen Ctr Mol Life Sci, Microscop Imaging Ctr, NL-6500 HB Nijmegen, Netherlands. Radboud Univ Nijmegen, Med Ctr, Nijmegen Ctr Mitochondrial Disorders, Dept Pediat, NL-6500 HB Nijmegen, Netherlands. Reprint: Koopman, WJH, Radboud Univ Nijmegen, Med Ctr, Nijmegen Ctr Mol Life
Sci, Dept Biochem, 286 Biochem,POB 9101, NL-6500 HB Nijmegen, Netherlands. E-mail: w.koopman@ncmls.ru.nl
Author Keywords:
KeyWords Plus: NADH-UBIQUINONE OXIDOREDUCTASE; ELECTRON-TRANSPORT-CHAIN; BOVINE HEART-
MITOCHONDRIA; OXIDATIVE-PHOSPHORYLATION SYSTEM; RESPIRATORY-CHAIN;
CELL-DEATH; SUPEROXIDE-PRODUCTION; ENDOPLASMIC-RETICULUM; HYDROGEN-
PEROXIDE; ESCHERICHIA-COLI
Abstract: Virtually every mammalian cell contains mitochondria. These double-membrane organelles continuously change shape and position and contain the complete metabolic machinery for the oxidative conversion of pyruvate, fatty acids, and amino acids into ATP. Mitochondria are crucially involved in cellular Ca2+ and redox homeostasis and apoptosis induction. Maintenance of mitochondrial function and integrity requires an inside-negative potential difference across the mitochondrial inner membrane. This potential is sustained by the electron-transport chain (ETC). NADH: ubiquinone oxidoreductase or complex I (CI), the first and largest protein complex of the ETC, couples the oxidation of NADH to the reduction of ubiquinone. During this process, electrons can escape from CI and react with ambient oxygen to produce superoxide and derived reactive oxygen species (ROS). Depending on the balance between their production and removal by antioxidant systems, ROS may function as signaling molecules or induce damage to a variety of biomolecules or both. The latter ultimately leads to a loss of mitochondrial and cellular function and integrity. In this review, we discuss (a) the role of CI in mitochondrial functioning; (b) the composition, structure, and biogenesis of CI; (c) regulation of CI function; (d) the role of CI in ROS generation; and (e) adaptive responses to CI deficiency. Antioxid. Redox Signal. 12, 1431-1470.
Cited References: ACINPEREZ R, 2004, MOL CELL, V13, P805 ACINPEREZ R, 2008, MOL CELL, V32, P529, DOI 10.1016/j.molcel.2008.10.021 ACINPEREZ R, 2009, CELL METAB, V9, P265, DOI 10.1016/j.cmet.2009.01.012 ADAMVIZI V, 2005, ANTIOXID REDOX SIGN, V7, P1140 ADAMVIZI V, 2006, TRENDS PHARMACOL SCI, V27, P639, DOI 10.1016/j.tips.2006.10.005 AHN BH, 2008, P NATL ACAD SCI USA, V105, P14447, DOI 10.1073/pnas.0803790105 ARRINGTON DD, 2006, AM J PHYSIOL-CELL PH, V291, PC1159, DOI 10.1152/ajpcell.00207.2006 BARRIENTOS A, 1999, J BIOL CHEM, V274, P16188 BAUTISTA J, 2000, BIOCHEM BIOPH RES CO, V275, P890 BECKER T, 2008, BBA-BIOENERGETICS, V1777, P557 BENARD G, 2006, AM J PHYSIOL-CELL PH, V291, PC1172, DOI 10.1152/ajpcell.00195.2006 BENARD G, 2007, J CELL SCI, V120, P838, DOI 10.1242/jcs.03381 BENARD G, 2008, ANTIOXID REDOX SIGN, V10, P1313, DOI 10.1089/ars.2007.2000 BENARD G, 2008, INT J BIOCHEM CELL B, V40, P1543, DOI 10.1016/j.biocel.2007.11.023 BENIT P, 2008, PLOS ONE, V3, ARE3208 BERNARDI P, 2007, NOVART FDN SYMP, V287, P157 BERRIDGE MJ, 2003, NAT REV MOL CELL BIO, V4, P517, DOI 10.1038/nrm1155 BERRISFORD JM, 2008, BIOCHEMISTRY-US, V47, P10262, DOI 10.1021/bi801160u BIANCHI C, 2004, J BIOL CHEM, V279, P36562, DOI 10.1074/jbc.M405135200 BIASUTTO L, 2008, BIOORG MED CHEM LETT, V18, P5594, DOI 10.1016/j.bmcl.2008.08.100 BIENERT GP, 2007, J BIOL CHEM, V282, P1183, DOI 10.1074/jbc.M603761200 BIHLMAIER K, 2008, ANN NY ACAD SCI, V1147, P293, DOI 10.1196/annals.1427.005 BLINOVA K, 2008, BIOCHEMISTRY-US, V47, P9636, DOI 10.1021/bi800307y BOEKEMA EJ, 2007, J BIOL CHEM, V282, P1, DOI 10.1074/jbc.R600031200 BOLENDER N, 2008, EMBO REP, V9, P42, DOI 10.1038/sj.embor.7401126 BORLAND MK, 2008, MOL NEURODEGENER, V5, P3 BORTOLAMI S, 2008, J BIOENERG BIOMEMBR, V40, P9, DOI 10.1007/s10863-008-9126-1 BOSSIS G, 2006, CELL DIV, V1, AR13 BOVERIS A, 2006, BBA-BIOENERGETICS, V1757, P535, DOI 10.1016/j.bbabio.2006.02.010 BRANDT U, 2006, ANNU REV BIOCHEM, V75, P69 BROOKES PS, 2004, AM J PHYSIOL-CELL PH, V287, P817 BROUGH D, 2005, BIOCHEM J 2, V392, P291, DOI 10.1042/BJ20050738 BUETTNER GR, 2006, FREE RADICAL BIO MED, V41, P1338, DOI 10.1016/j.freeradbiomed.2006.07.015 BUSCH KB, 2006, MOL MEMBR BIOL, V23, P509, DOI 10.1080/09687860600877292 CAMELLOALMARAZ C, 2006, AM J PHYSIOL-CELL PH, V291, PC1082, DOI 10.1152/ajpcell.00217.2006 CARLUCCI A, 2008, TRENDS CELL BIOL, V18, P604, DOI 10.1016/j.tcb.2008.09.006 CARRERAS MC, 2007, AM J PHYSIOL-CELL PH, V292, PC1569, DOI 10.1152/ajpcell.00248.2006 CARROLL J, 2005, MOL CELL PROTEOMICS, V4, P693, DOI 10.1074/mcp.M500014-MCP200 CARROLL J, 2006, J BIOL CHEM, V281, P32724, DOI 10.1074/jbc.M607135200 CASSEREAU J, 2008, NEUROGENETICS, V10, P145 CASTROGAGO M, 2008, BRAIN DEV, V31, P322 CHAN SHH, 2009, HYPERTENSION, V53, P217, DOI 10.1161/HYPERTENSIONAHA.108.116905 CHANCE B, 1955, NATURE, V176, P250 CHEN C, 2004, J BIOL CHEM, V279, P31761, DOI 10.1074/jbc.M401353200 CHEN CL, 2007, BIOCHEMISTRY-US, V46, P5754, DOI 10.1021/bi602580c CHEN YQ, 2007, J CELL SCI, V120, P4155, DOI 10.1242/jcs.011163 CHICCO AJ, 2007, AM J PHYSIOL-CELL PH, V292, PC33, DOI 10.1152/ajpcell.00243.2006 CHINTA SJ, 2006, FREE RADICAL BIO MED, V41, P1442, DOI 10.1016/j.freeradbiomed.2006.08.002 CHOI WS, 2008, P NATL ACAD SCI USA, V105, P15136, DOI 10.1073/pnas.0807581105 CHOKSI KB, 2004, BBA-MOL BASIS DIS, V1688, P95, DOI 10.1016/j.bbadis.2003.11.007 CHOKSI KB, 2008, FREE RADICAL BIO MED, V44, P1795, DOI 10.1016/j.freeradbiomed.2008.01.032 CLEMENTI E, 1998, P NATL ACAD SCI USA, V95, P7631 COCCO T, 2009, NEUROBIOL AGING, V30, P622, DOI 10.1016/j.neurobiolaging.2007.08.002 COCHEME HM, 2008, J BIOL CHEM, V283, P1786, DOI 10.1074/jbc.M708597200 COOPER HM, 2009, PLOS ONE, V4, ARE4986 COSTA ADT, 2008, AM J PHYSIOL-HEART C, V295, PH874, DOI 10.1152/ajpheart.01189.2007 DALLEDONNE I, 2009, TRENDS BIOCHEM SCI, V34, P85, DOI 10.1016/j.tibs.2008.11.002 DAUTREAUX B, 2007, NAT REV MOL CELL BIO, V8, P813, DOI 10.1038/nrm2256 DEBRITO OM, 2008, ANTIOXID REDOX SIGN, V10, P621, DOI 10.1089/ars.2007.1934 DEBRITO OM, 2008, NATURE, V456, P605, DOI 10.1038/nature07534 DERASMO D, 2008, CELL SIGNAL, V20, P989 DETKE S, 2008, ACTA TROP, V105, P16, DOI 10.1016/j.actatropica.2007.08.008 DETMER SA, 2007, NAT REV MOL CELL BIO, V8, P870, DOI 10.1038/nrm2275 DEVI L, 2008, J BIOL CHEM, V283, P9089, DOI 10.1074/jbcM710012200 DIETEREN CEJ, 2008, J BIOL CHEM, V283, P34753, DOI 10.1074/jbc.M807323200 DIMAURO S, 2009, BBA-MOL BASIS DIS, V1792, P1159, DOI 10.1016/j.bbadis.2008.10.015 DIMMER KS, 2006, PHYSIOLOGY, V21, P233, DOI 10.1152/physiol.00010.2006 DISTELMAIER F, 2008, CYTOM PART A A, V73, P129, DOI 10.1002/cyto.a.20503 DISTELMAIER F, 2009, BRAIN 4, V132, P833, DOI 10.1093/brain/awp058 DISTELMAIER F, 2009, J MOL MED-JMM, V87, P515, DOI 10.1007/s00109-009-0452-5 DISTLER AM, 2008, PROTEOMICS, V8, P4066, DOI 10.1002/pmic.200800102 DLASKOVA A, 2008, INT J BIOCHEM CELL B, V40, P2098, DOI 10.1016/j.bioce1.2008.02.007 DOUGHAN AK, 2007, ANTIOXID REDOX SIGN, V9, P1825, DOI 10.1089/ars.2007.1693 DROGE W, 2002, PHYSIOL REV, V82, P47 DROGE W, 2007, AGING CELL, V6, P361, DOI 10.1111/j.1474-9726.2007.00294.x DUDKINA NV, 2005, P NATL ACAD SCI USA, V102, P3225, DOI 10.1073/pnas.0408870102 DUDKINA NV, 2008, J BIOENERG BIOMEMBR, V40, P419, DOI 10.1007/s10863-008-9167-5 DUNNING CJR, 2007, EMBO J, V26, P3227, DOI 10.1038/sj.emboj.7601748 ECHTAY KS, 2007, FREE RADICAL BIO MED, V43, P1351, DOI 10.1016/j.freeradbiomed.2007.08.011 ENDLICHER R, 2009, PHYSIOL RES, V58, P658 ERUSALIMSKY JD, 2007, ARTERIOSCL THROM VAS, V27, P2524, DOI 10.1161/ATVBAHA.107.151167 ESTERHAZY D, 2008, BIOCHEMISTRY-US, V47, P3964, DOI 10.1021/bi702243b FATO R, 2008, BIOCHIM BIOPHYS ACTA, V1787, P384 FATO R, 2008, NEUROCHEM RES, V33, P2487, DOI 10.1007/s11064-008-9747-0 FEARNLEY IM, 2001, J BIOL CHEM, V276, P38345 FENDEL U, 2008, BBA-BIOENERGETICS, V1777, P660, DOI 10.1016/j.bbabio.2008.04.033 FINEL M, 1992, BIOCHEMISTRY-US, V31, P11425 FORMAN HJ, 2008, ARCH BIOCHEM BIOPHYS, V477, P183, DOI 10.1016/j.abb.2008.06.011 FREZZA C, 2009, SEMIN CANCER BIOL, V19, P4, DOI 10.1016/j.semcancer.2008.11.008 FRIEDRICH T, 1997, J THEOR BIOL, V187, P529 FRIEDRICH T, 2004, BBA-BIOENERGETICS, V1608, P1, DOI 10.1016/j.bbabio.2003.10.002 FRUHWIRTH GO, 2007, BBA-MOL BASIS DIS, V1772, P718, DOI 10.1016/j.bbadis.2007.04.009 GALKIN A, 2005, J BIOL CHEM, V280, P30129, DOI 10.1074/jbc.M504709200 GALKIN A, 2007, J BIOL CHEM, V282, P37448, DOI 10.1074/jbc.M707543200 GALKIN A, 2008, J BIOL CHEM, V283, P20907, DOI 10.1074/jbc.M803190200 GARLID KD, 2003, BBA-BIOENERGETICS, V1606, P23, DOI 10.1016/S0005-2728(03)00108-7 GENOVA ML, 2003, ITAL J BIOCHEM, V52, P58 GENOVA ML, 2008, BBA-BIOENERGETICS, V1777, P740, DOI 10.1016/j.bbabio.2008.04.007 GIORGIO M, 2007, NAT REV MOL CELL BIO, V8, P722 GIULIVI C, 2007, NOVART FDN SYMP, V287, P92 GONZALVEZ F, 2008, J CELL BIOL, V183, P681, DOI 10.1083/jcb.200803129 GOSTIMSKAYA IS, 2007, FEBS LETT, V581, P5803, DOI 10.1016/j.febslet.2007.11.048 GRIGORIEFF N, 1999, CURR OPIN STRUC BIOL, V9, P476 GRIMA R, 2008, ESSAYS BIOCHEM, V45, P41 GRIMSRUD PA, 2008, J BIOL CHEM, V283, P21837, DOI 10.1074/jbc.R700019200 GRIVENNIKOVA VG, 2006, BBA-BIOENERGETICS, V1757, P553, DOI 10.1016/j.bbabio.2006.03.013 GRIVERMIKOVA VG, 2007, BIOCHEMISTRY-US, V46, P10971, DOI 10.1021/bi7009822 GUENEBAUT V, 1997, J MOL BIOL, V265, P409 GUERREROCASTILLO S, 2009, BBA-BIOENERGETICS, V1787, P75, DOI 10.1016/j.bbabio.2008.10.008 GUILLERY O, 2008, NEUROMUSCULAR DISORD, V18, P319, DOI 10.1016/j.nmd.2007.12.008 GYULKHANDANYAN AV, 2004, J NEUROCHEM, V90, P405, DOI 10.1111/j.1471-4159.2004.02489.x HALL LML, 2008, FUTURE LIPIDOL, V3, P411, DOI 10.2217/17460875.3.4.411 HAN D, 2003, J BIOL CHEM, V278, P5557, DOI 10.1074/jbc.M210269200 HAN ES, 2008, PHYSIOL GENOMICS, V34, P112, DOI 10.1152/physiolgenomics.00239.2007 HANDSCHIN C, 2006, ENDOCR REV, V27, P728 HINCHLIFFE P, 2005, SCIENCE, V309, P771, DOI 10.1126/science.1113988 HIRST J, 2008, BIOCHEM SOC T 5, V36, P976, DOI 10.1042/BST0360976 HOOL LC, 2007, ANTIOXID REDOX SIGN, V9, P409, DOI 10.1089/ars.2006.1446 HOPPINS S, 2007, ANNU REV BIOCHEM, V76, P751, DOI 10.1146/annurev.biochem.76.071905.090048 HORBINSKI C, 2005, FREE RADICAL BIO MED, V38, P2, DOI 10.1016/j.freeradbiomed.2004.09.030 HORVATH R, 2008, NEUROTHERAPEUTICS, V5, P558 HOUTKOOPER RH, 2008, CELL MOL LIFE SCI, V65, P2493, DOI 10.1007/s00018-008-8030-5 HU Y, 2009, J BIOL CHEM, V284, P547, DOI 10.1074/jbc.M808518200 HUANG G, 2007, CELL DEATH DIFFER, V14, P327, DOI 10.1038/sj.cdd.4402004 HUANG GC, 2004, MOL CELL BIOL, V24, P8447, DOI 10.1128/MCB.24.19.8447-8456.2004 HURD TR, 2005, ANTIOXID REDOX SIGN, V7, P999 HURD TR, 2005, BIOCHEM SOC T 6, V33, P1390 HURD TR, 2007, J BIOL CHEM, V282, P22040, DOI 10.1074/jbc.M703591200 HURD TR, 2008, J BIOL CHEM, V283, P24801, DOI 10.1074/jbc.M803432200 HUTTEMANN M, 2007, BBA-MOL CELL RES, V1773, P1701 JACOBS KM, 2008, INT J BIOL SCI, V4, P291 JEYARAJU DV, 2008, BIOCHIM BIOPHYS ACTA, V1787, P1363 JEZEK P, 2005, INT J BIOCHEM CELL B, V37, P2478, DOI 10.1016/j.biocel.2005.05.013 JHA N, 2000, J BIOL CHEM, V275, P26096 JOHNSONCADWELL LI, 2007, J NEUROCHEM, V101, P1619, DOI 10.1111/j.1471-4159.2007.04516.x KAASIK A, 2007, AM J PHYSIOL-CELL PH, V292, PC157, DOI 10.1152/ajpcell.00272.2006 KAMINSKI M, 2007, MOL CELL BIOL, V27, P3625, DOI 10.1128/MCB.02295-06 KARP CM, 2007, ONCOGENE, V26, P1780, DOI 10.1038/sj.onc.1209980 KLINGENBERG M, 2008, BBA-BIOMEMBRANES, V1778, P1978, DOI 10.1016/j.bbamem.2008.04.011 KOENE S, 2009, J INTERN MED, V265, P193, DOI 10.1111/j.1365-2796.2008.02058.x KOOPMAN WJ, 2004, OXIDATIVE PHOSPHORYL, P130 KOOPMAN WJH, 2005, AM J PHYSIOL-CELL PH, V288, PC1440, DOI 10.1152/ajpcell.00607.2004 KOOPMAN WJH, 2005, AM J PHYSIOL-CELL PH, V289, PC881, DOI 10.1152/ajpcell.00104.2005 KOOPMAN WJH, 2007, AM J PHYSIOL-CELL PH, V293, PC22, DOI 10.1152/ajpcell.00194.2006 KOOPMAN WJH, 2007, BBA-BIOENERGETICS, V1767, P940, DOI 10.1016/j.bbabio.2007.03.013 KOOPMAN WJH, 2008, AM J PHYSIOL-CELL PH, V294, PC1124, DOI 10.1152/ajpcell.00079.2008 KOOPMAN WJH, 2008, BBA-BIOENERGETICS, V1777, P853, DOI 10.1016/j.bbabio.2008.03.028 KOOPMAN WJH, 2008, METHODS, V46, P304, DOI 10.1016/j.ymeth.2008.09.018 KORSHUNOV S, 2006, J BACTERIOL, V188, P6326, DOI 10.1128/JB.00554-06 KORZENIEWSKI B, 2007, BIOPHYS CHEM, V129, P93, DOI 10.1016/j.bpc.2007.05.013 KOWALCZYK JE, 2008, POSTEPY BIOCHEM, V54, P209 KRIEGER E, 2002, PROTEINS, V47, P393 KUSSMAUL L, 2006, P NATL ACAD SCI USA, V103, P7607, DOI 10.1109/pnas.0510977103 KWONG JQ, 2007, J CELL BIOL, V179, P1163, DOI 10.1083/jcb.200704059 LAMBERT AJ, 2008, FEBS LETT, V582, P1711, DOI 10.1016/j.febslet.2008.04.030 LAZAROU M, 2007, MOL CELL BIOL, V27, P4228, DOI 10.1128/MCB.00074-07 LAZAROU M, 2009, BBA-MOL CELL RES, V1793, P78, DOI 10.1016/j.bbamcr.2008.04.015 LEE CF, 2005, ANN NY ACAD SCI, V1042, P246, DOI 10.1196/annals.1338.027 LEMMAGRAY P, 2008, ANAL BIOCHEM, V382, P116, DOI 10.1016/j.ab.2008.07.029 LENAZ G, 2006, ITAL J BIOCHEM, V55, P232 LENAZ G, 2007, AM J PHYSIOL-CELL PH, V292, PC1221, DOI 10.1152/ajpcell.00263.2006 LENN T, 2008, MOL MICROBIOL, V70, P1397, DOI 10.1111/j.1365-2958.2008.06486.x LI NY, 2003, J BIOL CHEM, V278, P8516, DOI 10.1074/jbc.M210432200 LI YF, 2007, J BIOL CHEM, V282, P17557, DOI 10.1074/jbc.M701056200 LOMBARD DB, 2007, MOL CELL BIOL, V27, P8807, DOI 10.1128/MCB.01636-07 LU H, 2008, MOL BIOL CELL, V19, P1893, DOI 10.1091/mbc.E07-07-0683 MAAS MFPM, 2009, J MOL BIOL, V387, P259, DOI 10.1016/j.jmb.2008.12.025 MAILLOUX RJ, 2007, PLOS ONE, V2, ARE690 MALHOTRA JD, 2007, ANTIOXID REDOX SIGN, V9, P2277, DOI 10.1089/ars.2007.1782 MALKA F, 2005, EMBO REP, V6, P853, DOI 10.1038/sj.embor.7400488 MANNELLA CA, 2008, ANN NY ACAD SCI, V1147, P171, DOI 10.1196/annals.1427.020 MARGUET D, 2006, EMBO J, V25, P3446 MARQUES I, 2007, EUKARYOT CELL, V6, P2391, DOI 10.1128/EC.00149-07 MARTINVALET D, 2008, CELL, V133, P681, DOI 10.1016/j.cell.2008.03.032 MATSUZAKI S, 2007, BIOCHEMISTRY-US, V46, P1350, DOI 10.1021/bi0617916 MCKENZIE M, 2006, J MOL BIOL, V361, P462, DOI 10.1016/j.jmb.2006.06.057 MEEUSEN S, 2004, SCIENCE, V305, P1747, DOI 10.1126/science.1100612 MINAI L, 2008, MOL GENET METAB, V94, P120, DOI 10.1016/j.ymgme.2007.12.007 MOKRANJAC D, 2008, BBA-BIOENERGETICS, V1777, P758, DOI 10.1016/j.bbabio.2008.04.009 MORGNER N, 2008, BBA-BIOENERGETICS, V1777, P1384, DOI 10.1016/j.bbabio.2008.08.001 MORTIBOYS H, 2008, ANN NEUROL, V64, P555, DOI 10.1002/ana.21492 MULLER FL, 2008, BIOCHEM J 2, V409, P491, DOI 10.1042/BJ20071162 MUNOZ J, 2008, PROTEOMICS, V8, P1898, DOI 10.1002/pmic.200701085 MURAI M, 2007, BIOCHEMISTRY-US, V46, P6409, DOI 10.1021/bi7003697 MURAI M, 2009, BIOCHEMISTRY-US, V48, P688, DOI 10.1021/bi8019977 MURPHY MP, 2007, ANNU REV PHARMACOL, V47, P629, DOI 10.1146/annurev.pharmtox.47.120505.105110 MURPHY MP, 2009, BIOCHEM J 1, V417, P1, DOI 10.1042/BJ20081386 MURRAY J, 2003, J BIOL CHEM, V278, P37223, DOI 10.1074/jbc.M305694200 NAITHANI S, 2003, MOL BIOL CELL, V14, P324, DOI 10.1091/mbc.E02-08-0490 NG CF, 2007, FREE RADICAL RES, V41, P1201, DOI 10.1080/10715760701625075 NICHOLLS DG, 2002, BIOENERGETICS, V3 NUBEL E, 2009, PROTEOMICS, V9, P2408, DOI 10.1002/pmic.200800632 OGILVIE I, 2005, J CLIN INVEST, V115, P2784, DOI 10.1172/JCI26020 OKUN JG, 1999, J BIOL CHEM, V274, P2625 OLICHON A, 2006, BBA-MOL CELL RES, V1763, P500, DOI 10.1016/j.bbamcr.2006.04.03 OROURKE B, 2007, ANNU REV PHYSIOL, V69, P19, DOI 10.1146/annurev.physiol.69.031905.163804 OTT M, 2007, CELL DEATH DIFFER, V14, P1243, DOI 10.1038/sj.cdd.4402135 OWUSUANSAH E, 2008, NAT GENET, V40, P356, DOI 10.1038/ng.2007.50 PAGLIARINI DJ, 2008, CELL, V134, P112, DOI 10.1016/j.cell.2008.06.016 PALMIERI F, 2008, BBA-BIOENERGETICS, V1777, P564, DOI 10.1016/j.bbabio.2008.03.008 PALMISANO G, 2007, PROTEOMICS, V7, P1575, DOI 10.1002/pmic.200600801 PAPA S, 1996, BBA-BIOENERGETICS, V1276, P87 PAPA S, 2008, BBA-BIOENERGETICS, V1777, P719, DOI 10.1016/j.bbabio.2008.04.005 PAPA S, 2009, BBA-BIOENERGETICS, V1787, P502, DOI 10.1016/j.bbabio.2008.12.018 PARADIES G, 2002, GENE, V286, P135 PATHAK RU, 2008, BBA-BIOENERGETICS, V1777, P777, DOI 10.1016/j.bbabio.2008.05.443 PELLO R, 2008, HUM MOL GENET, V17, P4001, DOI 10.1093/hmg/ddn303 PETERSEN DR, 2004, FREE RADICAL BIO MED, V37, P937, DOI 10.1016/j.freeradbiomed.2004.06.012 PETROSILLO G, 2009, FREE RADICAL BIO MED, V46, P88, DOI 10.1016/j.freeradbiomed.2008.09.031 PFANNER N, 2004, NAT STRUCT MOL BIOL, V11, P1044, DOI 10.1038/nsmb852 PINTON P, 2008, ONCOGENE, V27, P6407, DOI 10.1038/onc.2008.308 PIZZO P, 2007, TRENDS CELL BIOL, V17, P511 PLETJUSHKINA OY, 2006, BBA-BIOENERGETICS, V1757, P518, DOI 10.1016/j.bbabio.2006.03.018 POCSFALVI G, 2007, MOL CELL PROTEOMICS, V6, P231, DOI 10.1074/mcp.M600268-MCP200 POHL T, 2008, BIOCHEM SOC T 5, V36, P971, DOI 10.1042/BST0360971 PORCELLI AM, 2009, J BIOL CHEM, V284, P2045, DOI 10.1074/jbc.M807321200 POTLA R, 2006, MOL CELL BIOL, V26, P8562, DOI 10.1128/MCB.00497-06 RADERMACHER M, 2006, J STRUCT BIOL, V154, P269, DOI 10.1016/j.jsb.2006.02.011 REDMOND RW, 2006, PHOTOCHEM PHOTOBIOL, V82, P1176 REEVES MB, 2007, SCIENCE, V316, P1345, DOI 10.1126/science.1142984 REMACLE C, 2008, MOL GENET GENOMICS, V280, P93, DOI 10.1007/s00438-008-0350-5 RICCI JE, 2004, CELL, V117, P773 ROSSI AE, 2009, EXERC SPORT SCI REV, V37, P29 ROSSIGNOL R, 2003, BIOCHEM J 3, V370, P751, DOI 10.1042/BJ20021594 SAADA A, 2008, AM J HUM GENET, V82, P32, DOI 10.1016/j.ajhg.2007.08.003 SAADA A, 2009, AM J HUM GENET, V84, P718, DOI 10.1016/j.ajhg.2009.04.020 SABLINA AA, 2005, NAT MED, V11, P1306, DOI 10.1038/nm1320 SANTIAGO APSA, 2008, BIOCHIMIE, V90, P1566, DOI 10.1016/j.biochi.2008.06.013 SAOTOME M, 2008, P NATL ACAD SCI USA, V105, P20728, DOI 10.1073/pnas.0808953105 SARAN M, 1994, CHEM-BIOL INTERACT, V90, P35 SAUVE AA, 2006, ANNU REV BIOCHEM, V75, P435, DOI 10.1146/annurev.biochem.74.082803.133500 SAUVE AA, 2009, CURR PHARM DESIGN, V15, P45 SAZANOV LA, 2000, BIOCHEMISTRY-US, V39, P7229 SAZANOV LA, 2000, J MOL BIOL, V302, P455 SAZANOV LA, 2006, SCIENCE, V311, P1430, DOI 10.1126/science.1123809 SAZANOV LA, 2007, BIOCHEMISTRY-US, V46, P2275, DOI 10.1021/bi602508x SCARPULLA RC, 2002, BBA-GENE STRUCT EXPR, V1576, P1 SCARPULLA RC, 2006, J CELL BIOCHEM, V97, P673, DOI 10.1002/jcb.20743 SCARPULLA RC, 2008, PHYSIOL REV, V88, P611, DOI 10.1152/physrev.00025.2007 SCHAFER FQ, 2001, FREE RADICAL BIO MED, V30, P1191 SCHAGGER H, 2002, BBA-BIOENERGETICS, V1555, P154 SCHAGGER H, 2004, J BIOL CHEM, V279, P36349, DOI 10.1074/jbc.M404033200 SCHEFFLER IE, 1999, MITOCHONDRIA SCHILLING B, 2005, FEBS LETT, V579, P2485, DOI 10.1016/j.febslet.2005.03.061 SCHLAME M, 2000, PROG LIPID RES, V39, P257 SCHLICKER C, 2008, J MOL BIOL, V382, P790, DOI 10.1016/j.jmb.2008.07.048 SCHWER B, 2006, P NATL ACAD SCI USA, V103, P10224, DOI 10.1073/pnas.0603968103 SHARPLEY MS, 2006, BIOCHEMISTRY-US, V45, P241, DOI 10.1021/bi051809x SHERER TB, 2001, BRAIN RES, V891, P94 SHERER TB, 2007, J NEUROCHEM, V100, P1469, DOI 10.1111/j.1471-4159.2006.04333.x SMEITINK J, 2001, J BIOENERG BIOMEMBR, V33, P259 SMEITINK J, 2001, NAT REV GENET, V2, P342 SMITH RAJ, 2008, ANN NY ACAD SCI, V1147, P105, DOI 10.1196/annals.1427.003 SOLAINI G, 2007, BIOSCIENCE REP, V27, P11 STARKOV AA, 2008, ANN NY ACAD SCI, V1147, P37, DOI 10.1196/annals.1427.015 STOJANOVSKI D, 2008, BBA-MOL CELL RES, V1783, P610 SUGIANA C, 2008, AM J HUM GENET, V83, P468, DOI 10.1016/j.ajhg.2008.09.009 SUTHAMMARAK W, 2009, J BIOL CHEM, V284, P6425, DOI 10.1074/jbc.M805733200 SWERDLOW RH, 2007, ANTIOXID REDOX SIGN, V9, P1591, DOI 10.1089/ars.2007.1676 SZABO C, 2007, NAT REV DRUG DISCOV, V6, P662, DOI 10.1038/nrd2222 SZETO HH, 2008, ANN NY ACAD SCI, V1147, P112, DOI 10.1196/annals.1427.013 TANG TD, 2009, J BIOL CHEM, V284, P5414, DOI 10.1074/jbc.M807797200 TOCILESCU MA, 2007, J BIOL CHEM, V282, P29514, DOI 10.1074/jbc.M704519200 TRETTER L, 2007, J NEUROCHEM, V103, P1864 TRETTER L, 2007, NEUROCHEM RES, V32, P569, DOI 10.1007/s11064-006-9130-y TYYNISMAA H, 2009, EMBO REP, V10, P137, DOI 10.1038/embor.2008.242 UGALDE C, 2004, HUM MOL GENET, V13, P2461, DOI 10.1093/hmg/ddh262 UGALDE C, 2004, HUM MOL GENET, V13, P659, DOI 10.1093/hmg/ddh071 VALKO M, 2007, INT J BIOCHEM CELL B, V39, P44, DOI 10.1016/j.biocel.2006.07.001 VALSECCHI F, 2009, BBA-MOL BASIS DIS, V1792, P1130, DOI 10.1016/j.bbadis.2009.01.001 VEAL EA, 2007, MOL CELL, V26, P1, DOI 10.1016/j.molcel.2007.03.016 VERKAART S, 2007, BBA-MOL BASIS DIS, V1772, P1041, DOI 10.1016/j.bbadis.2007.05.004 VERKAART S, 2007, BBA-MOL BASIS DIS, V1772, P373, DOI 10.1016/j.bbadis.2006.12.009 VISCH HJ, 2004, J BIOL CHEM, V279, P40328, DOI 10.1074/jbc.M408068200 VISCH HJ, 2006, AM J PHYSIOL-CELL PH, V291, PC308, DOI 10.1152/ajpcell.00561.2005 VISCH HJ, 2006, BBA-MOL BASIS DIS, V1762, P115, DOI 10.1016/j.bbadis.2005.09.001 VOGEL RO, 2007, BBA-BIOENERGETICS, V1767, P1215, DOI 10.1016/j.bbabio.2007.07.008 VOGEL RO, 2007, GENE DEV, V21, P615, DOI 10.1101/gad.408407 VOGEL RO, 2007, J BIOL CHEM, V282, P7582, DOI 10.1074/jbc.M609410200 VONCK J, 2009, BBA-MOL CELL RES, V1793, P117, DOI 10.1016/j.bbamcr.2008.05.019 WALSH CT, 2006, POSTTRANSLATIONAL MO WANG W, 2008, CELL, V134, P279, DOI 10.1016/j.cell.2008.06.017 WANG XN, 2009, CELL, V136, P163, DOI 10.1016/j.cell.2008.11.046 WEGRZYN J, 2009, SCIENCE, V323, P793, DOI 10.1126/science.1164551 WEGRZYN P, 2009, BMC CELL BIOL, V10, AR23 WILLEMS PHGM, 2008, CELL CALCIUM, V44, P123, DOI 10.1016/j.ceca.2008.01.002 WILLEMS PHGM, 2009, INT J BIOCHEM CELL B, V41, P1773, DOI 10.1016/j.biocel.2009.01.012 WINTERBOURN CC, 2008, NAT CHEM BIOL, V4, P278, DOI 10.1038/nchembio.85 WITTIG I, 2006, BBA-BIOENERGETICS, V1757, P1066, DOI 10.1016/j.bbabio.2006.05.006 WITTIG I, 2009, BBA-BIOENERGETICS, V1787, P672, DOI 10.1016/j.bbabio.2008.12.016 WONG CM, 2008, CIRC RES, V102, P310, DOI 10.1161/CIRCRESAHA.107.159814 XIAO CC, 2003, GENE DEV, V17, P2933 YADAVA N, 2008, INT J BIOCHEM CELL B, V40, P447 YI MQ, 2004, J CELL BIOL, V167, P661, DOI 10.1083/jcb.200406038 YING WH, 2008, ANTIOXID REDOX SIGN, V10, P179, DOI 10.1089/ars.2007.1672 ZHANG L, 2008, J AM SOC MASS SPECTR, V19, P1875, DOI 10.1016/j.jasms.2008.08.004 ZHANG XM, 2008, BMC CELL BIOL, V9, AR8 ZICK M, 2008, BIOCHIM BIOPHYS ACTA, V1793, P5 ZICKERMANN V, 2008, J BIOENERG BIOMEMBR, V40, P475, DOI 10.1007/s10863-008-9171-9 ZIMA AV, 2006, CARDIOVASC RES, V71, P310, DOI 10.1016/j.cardiores.2006.02.019 |